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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Sox5_Sry

Z-value: 0.25

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Transcription factors associated with Sox5_Sry

Gene Symbol	Gene ID	Gene Info
Sox5 Ensembl NCBI MGI UniProt	ENSMUSG00000041540.10	SRY (sex determining region Y)-box 5
Sry Ensembl NCBI MGI UniProt	ENSMUSG00000069036.3	sex determining region of Chr Y

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_144180728_144181748	Sox5	22819	0.269213	0.65	2.2e-08	Click!
chr6_143832506_143833713	Sox5	113979	0.064402	-0.59	6.2e-07	Click!
chr6_144782118_144782709	Sox5	436	0.833242	0.37	3.6e-03	Click!
chr6_144115538_144115689	Sox5	88444	0.089482	-0.36	4.2e-03	Click!
chr6_144264338_144264733	Sox5	54967	0.168418	0.36	4.3e-03	Click!

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_120022870_120023448	0.16	Xirp1	xin actin-binding repeat containing 1	439	0.69
chr2_57698269_57698925	0.12	Gm25388	predicted gene, 25388	44775	0.15
chr8_102783050_102783452	0.12	Gm45258	predicted gene 45258	2209	0.27
chr13_115100230_115100381	0.12	Gm49395	predicted gene, 49395	1319	0.28
chr13_115100442_115100733	0.11	Gm49395	predicted gene, 49395	1037	0.33
chr7_68579903_68580131	0.11	Gm44887	predicted gene 44887	18837	0.2
chr3_52272538_52272708	0.11	Gm20402	predicted gene 20402	3188	0.17
chr10_13322562_13322713	0.11	Phactr2	phosphatase and actin regulator 2	1652	0.48
chr9_32697004_32697902	0.10	Ets1	E26 avian leukemia oncogene 1, 5' domain	1069	0.51
chrX_96456094_96457321	0.10	Heph	hephaestin	279	0.62
chr5_57723598_57724600	0.10	Gm42635	predicted gene 42635	294	0.83
chr10_24594191_24594469	0.10	Gm15270	predicted gene 15270	572	0.62
chr10_34485029_34485207	0.10	Frk	fyn-related kinase	1586	0.46
chr14_63945494_63946032	0.09	Sox7	SRY (sex determining region Y)-box 7	2090	0.29
chr10_125725497_125725755	0.09	Gm9102	predicted gene 9102	213095	0.02
chr18_10786308_10786708	0.09	Mir133a-1hg	Mir133a-1, Mir1b and Mir1a-2 host gene	625	0.41
chr17_48430197_48430460	0.09	Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	2290	0.18
chr2_84422956_84423235	0.09	Calcrl	calcitonin receptor-like	2171	0.3
chr3_54757529_54757680	0.09	Smad9	SMAD family member 9	2022	0.25
chr11_116108498_116109194	0.09	Trim47	tripartite motif-containing 47	727	0.48
chr6_29436481_29437108	0.09	Flnc	filamin C, gamma	3518	0.13
chr13_40729030_40729381	0.09	Tfap2a	transcription factor AP-2, alpha	198	0.87
chr1_81593421_81594539	0.09	Gm6198	predicted gene 6198	36497	0.2
chr19_36734732_36735279	0.09	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	1648	0.41
chr18_40257309_40257704	0.09	Kctd16	potassium channel tetramerisation domain containing 16	483	0.67
chr9_35424199_35424417	0.09	Cdon	cell adhesion molecule-related/down-regulated by oncogenes	720	0.64
chr3_123165344_123165495	0.09	Gm43287	predicted gene 43287	947	0.49
chr15_53342031_53342311	0.09	Ext1	exostosin glycosyltransferase 1	3488	0.33
chr3_138198375_138198616	0.08	4930579F01Rik	RIKEN cDNA 4930579F01 gene	11782	0.13
chr13_73261804_73262144	0.08	Irx4	Iroquois homeobox 4	1477	0.36
chr7_37213357_37213873	0.08	Gm28075	predicted gene 28075	73074	0.09
chr9_67045040_67045992	0.08	Tpm1	tropomyosin 1, alpha	1554	0.38
chr12_40198308_40199492	0.08	Gm17056	predicted gene 17056	244	0.64
chr1_134801821_134802618	0.08	Gm37949	predicted gene, 37949	234	0.87
chr8_87570056_87570373	0.08	4933402J07Rik	RIKEN cDNA 4933402J07 gene	6361	0.22
chr17_63451168_63451380	0.08	Fbxl17	F-box and leucine-rich repeat protein 17	437	0.88
chr13_110397628_110399698	0.08	Plk2	polo like kinase 2	866	0.68
chr2_14823792_14824714	0.08	Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	161	0.94
chr10_27615824_27617033	0.08	Lama2	laminin, alpha 2	368	0.8
chr8_48221738_48222471	0.08	Gm32842	predicted gene, 32842	48881	0.15
chr14_28517363_28517567	0.08	Wnt5a	wingless-type MMTV integration site family, member 5A	6014	0.22
chr1_192852982_192853436	0.08	Sertad4	SERTA domain containing 4	1462	0.26
chr10_44454467_44455437	0.08	Prdm1	PR domain containing 1, with ZNF domain	2258	0.31
chr2_114051146_114052179	0.08	Actc1	actin, alpha, cardiac muscle 1	1225	0.4
chr17_26841784_26842428	0.08	Nkx2-5	NK2 homeobox 5	541	0.65
chr14_79107094_79107330	0.08	Gm30970	predicted gene, 30970	811	0.51
chr16_91930196_91930347	0.08	D430001F17Rik	RIKEN cDNA D430001F17 gene	966	0.3
chr15_102252882_102253053	0.08	Rarg	retinoic acid receptor, gamma	327	0.77
chr2_127729042_127730365	0.08	Mall	mal, T cell differentiation protein-like	229	0.9
chr5_139422893_139423950	0.08	Gper1	G protein-coupled estrogen receptor 1	141	0.93
chr14_65326240_65326874	0.08	Gm48433	predicted gene, 48433	226	0.92
chr16_43503039_43503193	0.07	Zbtb20	zinc finger and BTB domain containing 20	498	0.85
chr12_70828137_70828628	0.07	Frmd6	FERM domain containing 6	2693	0.24
chr4_143300007_143300403	0.07	Pdpn	podoplanin	641	0.68
chr4_136142605_136142974	0.07	Id3	inhibitor of DNA binding 3	708	0.58
chr15_97004514_97004856	0.07	Slc38a4	solute carrier family 38, member 4	15266	0.26
chr17_76484714_76484865	0.07	Gm50028	predicted gene, 50028	145594	0.05
chr5_134988019_134988170	0.07	Cldn3	claudin 3	1880	0.15
chr14_120279572_120279920	0.07	Mbnl2	muscleblind like splicing factor 2	4016	0.31
chr1_187996852_187997015	0.07	Esrrg	estrogen-related receptor gamma	894	0.66
chr3_34691662_34692725	0.07	Gm43206	predicted gene 43206	9560	0.13
chr17_12768117_12768491	0.07	Igf2r	insulin-like growth factor 2 receptor	1360	0.31
chr1_185481839_185482593	0.07	5033404E19Rik	RIKEN cDNA 5033404E19 gene	5078	0.16
chr15_102259293_102259444	0.07	Rarg	retinoic acid receptor, gamma	1851	0.17
chr3_8594088_8594846	0.07	Gm18822	predicted gene, 18822	22037	0.15
chr17_87142136_87142409	0.07	Socs5	suppressor of cytokine signaling 5	34414	0.12
chr6_146190446_146190623	0.07	Itpr2	inositol 1,4,5-triphosphate receptor 2	6426	0.28
chr16_56479571_56479912	0.07	Abi3bp	ABI gene family, member 3 (NESH) binding protein	1841	0.47
chr2_68782317_68783265	0.07	Gm13612	predicted gene 13612	48226	0.11
chr9_40717623_40717874	0.07	Gm16095	predicted gene 16095	2238	0.17
chr3_38015645_38016389	0.07	Gm22899	predicted gene, 22899	20782	0.16
chr16_45842068_45842739	0.07	Phldb2	pleckstrin homology like domain, family B, member 2	1831	0.39
chr18_43391464_43391742	0.07	Dpysl3	dihydropyrimidinase-like 3	1774	0.41
chr10_23177086_23177436	0.07	Eya4	EYA transcriptional coactivator and phosphatase 4	8305	0.24
chr5_3488483_3488698	0.07	Gm17590	predicted gene, 17590	7717	0.13
chr12_73043399_73043995	0.07	Six1	sine oculis-related homeobox 1	882	0.62
chr18_23497982_23498622	0.07	Dtna	dystrobrevin alpha	1467	0.56
chrX_43427105_43427755	0.06	Tenm1	teneurin transmembrane protein 1	1573	0.42
chr5_53564312_53564803	0.06	Rbpj	recombination signal binding protein for immunoglobulin kappa J region	8723	0.2
chr1_162216561_162216955	0.06	Dnm3os	dynamin 3, opposite strand	865	0.43
chr16_4755196_4755446	0.06	Hmox2	heme oxygenase 2	1524	0.27
chr6_94183402_94184029	0.06	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	99310	0.08
chr6_18547797_18548305	0.06	Cttnbp2	cortactin binding protein 2	33208	0.19
chr7_89406807_89407562	0.06	Fzd4	frizzled class receptor 4	2829	0.19
chr10_38970342_38970493	0.06	Lama4	laminin, alpha 4	4745	0.27
chr10_5309229_5309911	0.06	Gm23573	predicted gene, 23573	47603	0.16
chr2_85056145_85056296	0.06	Tnks1bp1	tankyrase 1 binding protein 1	1939	0.22
chr12_119945587_119946924	0.06	Tmem196	transmembrane protein 196	155	0.95
chr11_50381300_50381698	0.06	Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	1448	0.31
chr11_106714520_106715257	0.06	Pecam1	platelet/endothelial cell adhesion molecule 1	58	0.97
chr8_25520662_25521310	0.06	Fgfr1	fibroblast growth factor receptor 1	1149	0.37
chr1_140182332_140182724	0.06	Cfh	complement component factor h	752	0.73
chr1_150992792_150993732	0.06	Hmcn1	hemicentin 1	173	0.95
chr5_41556543_41557296	0.06	Rab28	RAB28, member RAS oncogene family	70583	0.12
chr16_29540875_29541725	0.06	Atp13a4	ATPase type 13A4	183	0.96
chr19_32107415_32107757	0.06	Asah2	N-acylsphingosine amidohydrolase 2	563	0.82
chr3_79683507_79683658	0.06	Gm26984	predicted gene, 26984	6706	0.16
chr1_119348849_119349000	0.06	Gm29455	predicted gene 29455	19682	0.17
chr11_25356867_25358335	0.06	4933427E13Rik	RIKEN cDNA 4933427E13 gene	27644	0.22
chr5_32140229_32140654	0.06	Fosl2	fos-like antigen 2	4268	0.18
chr18_32818058_32818628	0.06	Tslp	thymic stromal lymphopoietin	1483	0.34
chr2_73351761_73352316	0.06	Gm13703	predicted gene 13703	5230	0.13
chr10_4374632_4374850	0.06	Zbtb2	zinc finger and BTB domain containing 2	866	0.52
chr5_43776922_43777113	0.06	Fbxl5	F-box and leucine-rich repeat protein 5	3417	0.14
chr5_75155621_75156099	0.06	Pdgfra	platelet derived growth factor receptor, alpha polypeptide	39	0.89
chr17_10316482_10317094	0.06	Qk	quaking	2573	0.33
chr19_3685416_3685683	0.06	Lrp5	low density lipoprotein receptor-related protein 5	1007	0.4
chr7_41979147_41979298	0.06	Vmn2r-ps57	vomeronasal 2, receptor, pseudogene 57	1706	0.36
chr18_43841982_43842133	0.06	Gm41715	predicted gene, 41715	1961	0.3
chr8_6907811_6908058	0.06	Gm44909	predicted gene 44909	76956	0.11
chr1_61055351_61055642	0.06	Rpl17-ps1	ribosomal protein L17, pseudogene 1	20178	0.17
chr2_167239298_167240893	0.06	Ptgis	prostaglandin I2 (prostacyclin) synthase	494	0.75
chr2_115512707_115513160	0.06	3110099E03Rik	RIKEN cDNA 3110099E03 gene	726	0.75
chr3_99233643_99234868	0.06	Tbx15	T-box 15	6126	0.15
chr1_62647919_62648262	0.06	Gm11600	predicted gene 11600	9698	0.18
chr13_93612831_93613054	0.06	Gm15622	predicted gene 15622	12440	0.16
chr5_3432895_3433605	0.06	Cdk6	cyclin-dependent kinase 6	37699	0.12
chr3_30006216_30006441	0.06	Mecom	MDS1 and EVI1 complex locus	5111	0.22
chr2_61494282_61494507	0.06	Gm22338	predicted gene, 22338	1628	0.51
chr19_24251735_24252236	0.06	Fxn	frataxin	26186	0.14
chr19_58859577_58860158	0.06	Hspa12a	heat shock protein 12A	771	0.65
chr5_134742346_134742912	0.05	Gm30003	predicted gene, 30003	4413	0.17
chr3_53525847_53526208	0.05	Frem2	Fras1 related extracellular matrix protein 2	3007	0.18
chr13_38145014_38146012	0.05	Dsp	desmoplakin	5781	0.18
chr6_116651389_116652299	0.05	Depp1	DEPP1 autophagy regulator	1148	0.32
chr2_33218844_33219764	0.05	Angptl2	angiopoietin-like 2	3187	0.21
chr4_34328044_34328577	0.05	Gm12751	predicted gene 12751	25733	0.18
chr9_24766942_24767354	0.05	Tbx20	T-box 20	2532	0.28
chr3_137343040_137343246	0.05	Emcn	endomucin	1969	0.42
chr2_76982792_76983214	0.05	Ttn	titin	456	0.86
chr10_44452907_44453510	0.05	Prdm1	PR domain containing 1, with ZNF domain	4002	0.23
chr6_15405115_15405989	0.05	Gm25470	predicted gene, 25470	571	0.83
chr15_91709273_91710162	0.05	Lrrk2	leucine-rich repeat kinase 2	29231	0.19
chr12_95691954_95693678	0.05	Flrt2	fibronectin leucine rich transmembrane protein 2	590	0.73
chr3_154269822_154270217	0.05	Slc44a5	solute carrier family 44, member 5	12545	0.18
chr17_12763317_12763493	0.05	Igf2r	insulin-like growth factor 2 receptor	6259	0.13
chr9_116173153_116173304	0.05	Tgfbr2	transforming growth factor, beta receptor II	2037	0.31
chrX_114476657_114476851	0.05	Klhl4	kelch-like 4	2150	0.37
chr10_21924319_21924470	0.05	Sgk1	serum/glucocorticoid regulated kinase 1	4076	0.23
chr2_62572999_62574382	0.05	Fap	fibroblast activation protein	130	0.97
chr6_147086429_147087322	0.05	Mansc4	MANSC domain containing 4	126	0.95
chr13_53283065_53283604	0.05	Ror2	receptor tyrosine kinase-like orphan receptor 2	2215	0.39
chr10_11250316_11250467	0.05	4930432B10Rik	RIKEN cDNA 4930432B10 gene	30607	0.12
chr1_58930482_58930757	0.05	Trak2	trafficking protein, kinesin binding 2	8922	0.16
chr4_32430676_32431345	0.05	Bach2	BTB and CNC homology, basic leucine zipper transcription factor 2	13575	0.26
chr16_20099317_20099468	0.05	Klhl24	kelch-like 24	1800	0.36
chr1_14308374_14310407	0.05	Eya1	EYA transcriptional coactivator and phosphatase 1	446	0.88
chr9_35423074_35423780	0.05	Cdon	cell adhesion molecule-related/down-regulated by oncogenes	161	0.95
chr14_90028075_90028226	0.05	Gm48941	predicted gene, 48941	57742	0.15
chr5_43776669_43776821	0.05	Fbxl5	F-box and leucine-rich repeat protein 5	3145	0.15
chr1_163358065_163358620	0.05	Gm24940	predicted gene, 24940	43941	0.11
chr10_85183402_85183765	0.05	Cry1	cryptochrome 1 (photolyase-like)	1481	0.42
chr10_103021254_103021450	0.05	Alx1	ALX homeobox 1	1222	0.49
chr3_89688580_89688818	0.05	Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	26181	0.13
chr2_6873585_6874006	0.05	Celf2	CUGBP, Elav-like family member 2	1198	0.49
chr10_53377941_53378236	0.05	Gm47641	predicted gene, 47641	1364	0.29
chr7_27168286_27168475	0.05	Egln2	egl-9 family hypoxia-inducible factor 2	1578	0.16
chr5_92899677_92900334	0.05	Shroom3	shroom family member 3	2012	0.38
chr3_149844857_149845745	0.05	Gm31121	predicted gene, 31121	184905	0.03
chr2_172934875_172936042	0.05	Bmp7	bone morphogenetic protein 7	4634	0.21
chr5_13628238_13629170	0.05	Gm43718	predicted gene 43718	10889	0.19
chr16_25802021_25802276	0.05	Trp63	transformation related protein 63	232	0.96
chr10_7182673_7182942	0.05	Cnksr3	Cnksr family member 3	29430	0.23
chr9_87724164_87724694	0.05	D030062O11Rik	RIKEN cDNA D030062O11 gene	4856	0.19
chr14_61043748_61044093	0.05	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	2549	0.3
chr13_59073511_59074258	0.05	Gm34245	predicted gene, 34245	4412	0.21
chr1_82284367_82285219	0.05	Irs1	insulin receptor substrate 1	6623	0.2
chr5_17642536_17642831	0.05	Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	51519	0.17
chr8_108241119_108241834	0.05	Zfhx3	zinc finger homeobox 3	246917	0.02
chr17_10310558_10310848	0.05	Qk	quaking	8658	0.24
chr6_118478476_118479294	0.05	Zfp9	zinc finger protein 9	435	0.79
chr5_131524957_131525108	0.05	Auts2	autism susceptibility candidate 2	9365	0.2
chr2_30864765_30865574	0.05	Prrx2	paired related homeobox 2	14150	0.12
chr9_63754826_63756126	0.05	Smad3	SMAD family member 3	2518	0.33
chr10_81363483_81364417	0.05	4930404N11Rik	RIKEN cDNA 4930404N11 gene	904	0.26
chr3_50443042_50444382	0.05	Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	98	0.98
chr14_64834470_64835221	0.05	Gm20111	predicted gene, 20111	4255	0.18
chr8_46502513_46502977	0.05	Acsl1	acyl-CoA synthetase long-chain family member 1	9913	0.16
chr2_70934994_70935182	0.05	Mettl8	methyltransferase like 8	38300	0.15
chr3_144714823_144715024	0.05	Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	5187	0.15
chr4_32302507_32304025	0.05	Bach2it1	BTB and CNC homology 2, intronic transcript 1	51505	0.14
chr2_174858675_174858999	0.05	Gm14616	predicted gene 14616	2548	0.24
chr2_44271339_44271725	0.05	Gm22867	predicted gene, 22867	157403	0.04
chr3_147999482_147999853	0.05	Gm43574	predicted gene 43574	130577	0.06
chr6_71629954_71630268	0.05	Kdm3a	lysine (K)-specific demethylase 3A	2575	0.2
chr18_6513819_6514449	0.05	Epc1	enhancer of polycomb homolog 1	1974	0.29
chrX_103185752_103186844	0.05	Nap1l2	nucleosome assembly protein 1-like 2	342	0.83
chr4_88935794_88936347	0.05	Gm49890	predicted gene, 49890	2451	0.18
chr16_42189565_42189855	0.05	Gm49737	predicted gene, 49737	4793	0.23
chr5_139128762_139129722	0.05	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	517	0.75
chr4_84671699_84671986	0.05	Bnc2	basonuclin 2	3154	0.3
chr12_108837523_108838185	0.05	Slc25a47	solute carrier family 25, member 47	790	0.33
chr18_47370463_47370942	0.05	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	1832	0.37
chr10_8761475_8762950	0.05	Sash1	SAM and SH3 domain containing 1	262	0.93
chr9_66806165_66806354	0.05	Ppp1r2-ps4	protein phosphatase 1, regulatory (inhibitor) subunit 2, pseudogene 4	321	0.8
chr5_66524169_66524487	0.05	Gm43343	predicted gene 43343	1784	0.29
chr3_127525390_127525541	0.05	Gm43354	predicted gene 43354	12565	0.07
chr2_105616227_105616777	0.05	Paupar	Pax6 upstream antisense RNA	44841	0.11
chr18_10707052_10707203	0.05	4930563E18Rik	RIKEN cDNA 4930563E18 gene	267	0.57
chr19_59941623_59942210	0.05	Rab11fip2	RAB11 family interacting protein 2 (class I)	1084	0.46

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	GO:0003166	bundle of His development(GO:0003166)
0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	GO:0030578	PML body organization(GO:0030578)
0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	GO:0033058	directional locomotion(GO:0033058)
0.1	GO:0072275	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	GO:0021603	cranial nerve formation(GO:0021603)
0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	GO:0090427	activation of meiosis(GO:0090427)
0.0	GO:1902896	terminal web assembly(GO:1902896)
0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	GO:0071438	invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	GO:0031433	telethonin binding(GO:0031433)
0.1	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	GO:0004096	catalase activity(GO:0004096)
0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	GO:0017040	ceramidase activity(GO:0017040)
0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	GO:0031005	filamin binding(GO:0031005)
0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation

Results for Sox5_Sry

Z-value: 0.25

Motif logo

Transcription factors associated with Sox5_Sry

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: