Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
Navigation
Downloads
Logo

Results for Spdef

Z-value: 0.48

Motif logo

logo of

Transcription factors associated with Spdef

Gene Symbol Gene ID Gene Info
Spdef
ENSMUSG00000024215.7 SAM pointed domain containing ets transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_27726230_27726673Spdef24380.1869960.411.3e-03Click!
chr17_27725174_27725943Spdef33310.1554510.321.2e-02Click!
chr17_27726810_27726998Spdef19850.2187320.283.3e-02Click!
chr17_27728247_27728914Spdef3090.8363500.191.4e-01Click!
chr17_27727948_27728145Spdef8430.4828270.123.5e-01Click!

Activity of the Spdef motif across conditions

Conditions sorted by the z-value of the Spdef motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_122459815_122460898 0.49 Zic5
 zinc finger protein of the cerebellum 5
 335
 0.81
chr19_12488341_12489388 0.46 Dtx4
 deltex 4, E3 ubiquitin ligase
 12590
 0.1
chr7_16404362_16406481 0.46 Gm45508
 predicted gene 45508
 1159
 0.29
chr9_108824114_108825614 0.45 Gm35025
 predicted gene, 35025
 3
 0.87
chr8_45509543_45510137 0.44 Sorbs2
 sorbin and SH3 domain containing 2
 1922
 0.33
chr3_31097203_31098928 0.43 Skil
 SKI-like
 1232
 0.48
chr7_16982884_16983633 0.42 Gm42372
 predicted gene, 42372
 172
 0.9
chr14_122477737_122477888 0.41 Zic2
 zinc finger protein of the cerebellum 2
 288
 0.83
chrX_153501207_153502250 0.37 Ubqln2
 ubiquilin 2
 3501
 0.22
chrX_170676003_170677019 0.36 Asmt
 acetylserotonin O-methyltransferase
 3867
 0.35
chrX_105390628_105392456 0.34 5330434G04Rik
 RIKEN cDNA 5330434G04 gene
 212
 0.93
chr2_6883618_6884699 0.32 Gm13389
 predicted gene 13389
 112
 0.85
chr4_156183474_156184054 0.32 Agrn
 agrin
 2137
 0.17
chr10_92160735_92161461 0.31 Rmst
 rhabdomyosarcoma 2 associated transcript (non-coding RNA)
 1663
 0.4
chr5_120433178_120434996 0.30 Gm27199
 predicted gene 27199
 2320
 0.19
chr13_34127276_34127957 0.30 Tubb2b
 tubulin, beta 2B class IIB
 2738
 0.15
chr13_83715222_83716973 0.30 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 5284
 0.15
chr11_80479429_80480178 0.29 Cdk5r1
 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
 2747
 0.26
chr1_6733530_6734383 0.29 St18
 suppression of tumorigenicity 18
 914
 0.7
chr11_96334278_96335532 0.28 Hoxb3
 homeobox B3
 6040
 0.08
chr4_110284419_110284817 0.28 Elavl4
 ELAV like RNA binding protein 4
 1998
 0.47
chr7_126041945_126042146 0.28 Gm44874
 predicted gene 44874
 22402
 0.17
chr8_89036575_89038609 0.27 Sall1
 spalt like transcription factor 1
 6570
 0.23
chr9_79829898_79830916 0.27 Filip1
 filamin A interacting protein 1
 591
 0.7
chr5_110543976_110545228 0.27 Galnt9
 polypeptide N-acetylgalactosaminyltransferase 9
 247
 0.9
chr4_6445169_6445688 0.27 Nsmaf
 neutral sphingomyelinase (N-SMase) activation associated factor
 899
 0.62
chr10_130279504_130280322 0.26 Neurod4
 neurogenic differentiation 4
 327
 0.87
chr5_73189782_73190392 0.26 Gm42571
 predicted gene 42571
 330
 0.81
chr9_44340460_44342952 0.26 Hmbs
 hydroxymethylbilane synthase
 473
 0.51
chr12_110187430_110189676 0.25 Gm34785
 predicted gene, 34785
 492
 0.73
chr10_79869256_79869624 0.25 Plppr3
 phospholipid phosphatase related 3
 2159
 0.09
chr1_77503797_77505059 0.25 Mir6352
 microRNA 6352
 7660
 0.19
chr13_83740463_83741042 0.25 C130071C03Rik
 RIKEN cDNA C130071C03 gene
 1889
 0.2
chr2_151968839_151969749 0.24 Mir1953
 microRNA 1953
 1677
 0.26
chr5_139543263_139545139 0.24 Uncx
 UNC homeobox
 303
 0.89
chr13_99780787_99781532 0.24 Gm24471
 predicted gene, 24471
 88630
 0.08
chr11_69554884_69555035 0.23 Efnb3
 ephrin B3
 5246
 0.09
chr2_24473566_24475385 0.23 Pax8
 paired box 8
 622
 0.64
chr14_122475443_122476757 0.23 Zic2
 zinc finger protein of the cerebellum 2
 665
 0.44
chr2_74725879_74728683 0.23 Hoxd4
 homeobox D4
 207
 0.67
chr7_70108517_70108933 0.23 Gm35325
 predicted gene, 35325
 98710
 0.07
chr9_108829719_108830312 0.23 Celsr3
 cadherin, EGF LAG seven-pass G-type receptor 3
 1725
 0.18
chr7_133700065_133700317 0.23 Uros
 uroporphyrinogen III synthase
 2111
 0.2
chr4_124660613_124661391 0.23 Gm2164
 predicted gene 2164
 3833
 0.13
chr13_112695809_112696082 0.23 Gm18883
 predicted gene, 18883
 3734
 0.17
chr5_139546076_139547826 0.23 Uncx
 UNC homeobox
 3053
 0.23
chr11_96331807_96334248 0.22 Hoxb3
 homeobox B3
 4965
 0.08
chr2_18044333_18044941 0.22 Skida1
 SKI/DACH domain containing 1
 65
 0.95
chr2_157026864_157027931 0.22 Soga1
 suppressor of glucose, autophagy associated 1
 75
 0.96
chr19_53897189_53897340 0.22 Pdcd4
 programmed cell death 4
 3434
 0.19
chr7_126979881_126980032 0.22 Cdipt
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
 1723
 0.13
chr6_134886811_134888239 0.22 Gpr19
 G protein-coupled receptor 19
 243
 0.87
chr19_45193534_45193685 0.22 Tlx1os
 T cell leukemia, homeobox 1, opposite strand
 34305
 0.12
chr7_73378126_73378277 0.22 A730056A06Rik
 RIKEN cDNA A730056A06 gene
 2427
 0.2
chr1_177446374_177448525 0.22 Zbtb18
 zinc finger and BTB domain containing 18
 1628
 0.31
chr14_77159311_77160431 0.22 Enox1
 ecto-NOX disulfide-thiol exchanger 1
 3091
 0.31
chr3_55782570_55784448 0.22 Nbea
 neurobeachin
 19
 0.96
chr1_132387629_132389330 0.22 Tmcc2
 transmembrane and coiled-coil domains 2
 1839
 0.25
chr2_151966993_151968089 0.22 Mir1953
 microRNA 1953
 76
 0.96
chr14_64588312_64589438 0.22 Mir124a-1hg
 Mir124-1 host gene (non-protein coding)
 341
 0.81
chr10_109832096_109833441 0.22 Nav3
 neuron navigator 3
 453
 0.9
chr9_65555338_65555833 0.22 Plekho2
 pleckstrin homology domain containing, family O member 2
 6579
 0.14
chr6_90781027_90782541 0.21 Iqsec1
 IQ motif and Sec7 domain 1
 188
 0.94
chr14_69269425_69270999 0.21 Gm27222
 predicted gene 27222
 11066
 0.09
chr6_28828230_28829085 0.21 Lrrc4
 leucine rich repeat containing 4
 1688
 0.37
chr2_146549745_146549896 0.21 4933406D12Rik
 RIKEN cDNA 4933406D12 gene
 6889
 0.27
chr1_115684558_115685809 0.21 Cntnap5a
 contactin associated protein-like 5A
 427
 0.58
chr4_154960570_154962200 0.21 Gm20421
 predicted gene 20421
 293
 0.57
chr8_122297355_122297506 0.21 Zfpm1
 zinc finger protein, multitype 1
 9890
 0.15
chr17_25930017_25930168 0.21 Pigq
 phosphatidylinositol glycan anchor biosynthesis, class Q
 916
 0.29
chr10_41070697_41071486 0.21 Gpr6
 G protein-coupled receptor 6
 1194
 0.41
chr1_66389272_66389745 0.21 Map2
 microtubule-associated protein 2
 2497
 0.31
chr13_37845693_37845844 0.21 Rreb1
 ras responsive element binding protein 1
 12166
 0.19
chr4_9269280_9270516 0.21 Clvs1
 clavesin 1
 551
 0.81
chr7_49915184_49916836 0.21 Slc6a5
 solute carrier family 6 (neurotransmitter transporter, glycine), member 5
 4310
 0.29
chr12_117157079_117158175 0.21 Gm10421
 predicted gene 10421
 5976
 0.31
chr15_59040592_59041370 0.21 Mtss1
 MTSS I-BAR domain containing 1
 384
 0.88
chr9_114404489_114404640 0.20 Glb1
 galactosidase, beta 1
 3456
 0.17
chr8_12399326_12400483 0.20 Gm25239
 predicted gene, 25239
 3501
 0.16
chr14_67320401_67320669 0.20 Gm6878
 predicted gene 6878
 5824
 0.18
chr9_91363064_91363717 0.20 Zic1
 zinc finger protein of the cerebellum 1
 336
 0.72
chr6_52160071_52161455 0.20 Hotairm1
 Hoxa transcript antisense RNA, myeloid-specific 1
 2239
 0.09
chr1_42691569_42692627 0.20 Pantr1
 POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1
 995
 0.42
chr3_152100022_152100538 0.20 Gipc2
 GIPC PDZ domain containing family, member 2
 2574
 0.21
chr2_165882235_165884653 0.20 Zmynd8
 zinc finger, MYND-type containing 8
 766
 0.54
chr15_82334694_82334845 0.20 Naga
 N-acetyl galactosaminidase, alpha
 1196
 0.22
chr13_59669031_59669197 0.20 Golm1
 golgi membrane protein 1
 6658
 0.1
chr13_58812962_58813113 0.20 C630044B11Rik
 RIKEN cDNA C630044B11 gene
 884
 0.48
chr2_84386593_84388183 0.20 Calcrl
 calcitonin receptor-like
 12030
 0.2
chr11_101084072_101084686 0.20 Coasy
 Coenzyme A synthase
 484
 0.59
chr16_94092357_94092508 0.20 Sim2
 single-minded family bHLH transcription factor 2
 7501
 0.15
chr8_26844152_26844303 0.20 2310008N11Rik
 RIKEN cDNA 2310008N11 gene
 2228
 0.31
chr11_77947804_77948671 0.19 Sez6
 seizure related gene 6
 3068
 0.17
chr9_73115681_73115832 0.19 Rsl24d1
 ribosomal L24 domain containing 1
 1160
 0.32
chr11_84526864_84527823 0.19 Lhx1os
 LIM homeobox 1, opposite strand
 1659
 0.31
chr14_69493829_69494689 0.19 Gm37094
 predicted gene, 37094
 6131
 0.11
chr6_88803678_88803829 0.19 Gm44001
 predicted gene, 44001
 1510
 0.26
chr4_21685165_21686049 0.19 Prdm13
 PR domain containing 13
 174
 0.95
chr11_78496560_78498132 0.19 Sarm1
 sterile alpha and HEAT/Armadillo motif containing 1
 112
 0.9
chr13_21913780_21914888 0.19 Gm44456
 predicted gene, 44456
 10682
 0.06
chr14_69275580_69276440 0.19 Gm20236
 predicted gene, 20236
 6130
 0.1
chr15_75620417_75621249 0.19 Zfp41
 zinc finger protein 41
 878
 0.44
chr17_32808045_32808304 0.19 Zfp811
 zinc finger protein 811
 1668
 0.15
chr5_5507730_5508026 0.19 Cldn12
 claudin 12
 6571
 0.17
chr2_51144318_51145477 0.19 Rnd3
 Rho family GTPase 3
 4197
 0.29
chrX_13244980_13245286 0.19 2010308F09Rik
 RIKEN cDNA 2010308F09 gene
 2603
 0.17
chr11_77486623_77487566 0.19 Ankrd13b
 ankyrin repeat domain 13b
 2572
 0.17
chr14_118234662_118235031 0.19 Gm4675
 predicted gene 4675
 1386
 0.29
chr4_117148050_117148208 0.18 Gm13015
 predicted gene 13015
 794
 0.3
chr11_117281297_117281448 0.18 Septin9
 septin 9
 15126
 0.17
chr5_120431744_120433119 0.18 Gm27199
 predicted gene 27199
 664
 0.41
chr6_55453986_55454137 0.18 Adcyap1r1
 adenylate cyclase activating polypeptide 1 receptor 1
 1884
 0.37
chr15_75619003_75619950 0.18 Zfp41
 zinc finger protein 41
 2235
 0.18
chr16_23889696_23891150 0.18 Sst
 somatostatin
 535
 0.77
chr16_97292625_97293406 0.18 Bace2
 beta-site APP-cleaving enzyme 2
 63727
 0.12
chr2_68365331_68365864 0.18 Stk39
 serine/threonine kinase 39
 922
 0.69
chr15_25624832_25625841 0.18 Myo10
 myosin X
 2787
 0.25
chr12_111690836_111691593 0.18 Gm36635
 predicted gene, 36635
 11868
 0.09
chr5_138278285_138278436 0.18 Gpc2
 glypican 2 (cerebroglycan)
 123
 0.87
chr1_174175177_174176129 0.18 Spta1
 spectrin alpha, erythrocytic 1
 2877
 0.14
chr7_27735092_27735839 0.18 Zfp60
 zinc finger protein 60
 902
 0.47
chr7_103812275_103812465 0.18 Hbb-bt
 hemoglobin, beta adult t chain
 1626
 0.15
chr7_49911362_49912424 0.17 Slc6a5
 solute carrier family 6 (neurotransmitter transporter, glycine), member 5
 193
 0.96
chr14_54567850_54568001 0.17 Ajuba
 ajuba LIM protein
 4157
 0.1
chr10_81114097_81114248 0.17 Map2k2
 mitogen-activated protein kinase kinase 2
 4440
 0.08
chr13_62885645_62885887 0.17 Fbp1
 fructose bisphosphatase 1
 2361
 0.22
chr10_19356598_19357962 0.17 Olig3
 oligodendrocyte transcription factor 3
 747
 0.72
chr7_119184137_119185474 0.17 Gpr139
 G protein-coupled receptor 139
 202
 0.96
chr7_121313033_121313561 0.17 4930486N12Rik
 RIKEN cDNA 4930486N12 gene
 53902
 0.1
chr5_98182267_98183697 0.17 Prdm8
 PR domain containing 8
 2004
 0.26
chr2_26207113_26207799 0.17 Gm27196
 predicted gene 27196
 754
 0.37
chr1_97540278_97540732 0.17 Gm37171
 predicted gene, 37171
 4943
 0.29
chr4_89691755_89691965 0.17 Dmrta1
 doublesex and mab-3 related transcription factor like family A1
 3662
 0.36
chr9_122595045_122595971 0.17 9530059O14Rik
 RIKEN cDNA 9530059O14 gene
 23006
 0.13
chr7_90886512_90887836 0.17 Gm45159
 predicted gene 45159
 102
 0.88
chr19_15339963_15340957 0.17 Gm24319
 predicted gene, 24319
 339544
 0.01
chrX_8072408_8072977 0.17 Suv39h1
 suppressor of variegation 3-9 1
 1566
 0.17
chr9_65144272_65144925 0.17 Igdcc3
 immunoglobulin superfamily, DCC subclass, member 3
 3386
 0.18
chr9_21557298_21557458 0.17 Carm1
 coactivator-associated arginine methyltransferase 1
 10220
 0.1
chr8_122613231_122613382 0.17 Trappc2l
 trafficking protein particle complex 2-like
 1660
 0.17
chr8_71680412_71681032 0.17 Jak3
 Janus kinase 3
 2387
 0.13
chr7_30331456_30331694 0.16 Gm50483
 predicted gene, 50483
 3223
 0.09
chr2_65563921_65564380 0.16 Scn3a
 sodium channel, voltage-gated, type III, alpha
 3342
 0.29
chr15_100402856_100403333 0.16 Slc11a2
 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
 149
 0.92
chr16_18213980_18215144 0.16 4933432I09Rik
 RIKEN cDNA 4933432I09 gene
 699
 0.36
chr11_120825651_120826165 0.16 Fasn
 fatty acid synthase
 1361
 0.25
chr5_115945354_115946075 0.16 Cit
 citron
 417
 0.82
chr8_121300864_121302289 0.16 Gm26815
 predicted gene, 26815
 55260
 0.11
chr4_129261016_129261208 0.16 C77080
 expressed sequence C77080
 292
 0.75
chr8_104734057_104734499 0.16 Ces2a
 carboxylesterase 2A
 250
 0.83
chr8_105689654_105689805 0.16 Carmil2
 capping protein regulator and myosin 1 linker 2
 1177
 0.25
chr10_81212943_81213094 0.16 Atcay
 ataxia, cerebellar, Cayman type
 258
 0.77
chr5_115362856_115363022 0.16 4930401G09Rik
 RIKEN cDNA 4930401G09 gene
 2816
 0.11
chr15_80674911_80675205 0.16 Fam83f
 family with sequence similarity 83, member F
 3211
 0.17
chr12_29534253_29535510 0.16 Gm20208
 predicted gene, 20208
 10
 0.8
chr12_100998075_100998234 0.16 Gm36756
 predicted gene, 36756
 5182
 0.14
chr7_36704669_36704859 0.16 Gm37452
 predicted gene, 37452
 5410
 0.14
chr11_55600811_55601094 0.16 Glra1
 glycine receptor, alpha 1 subunit
 6781
 0.21
chr13_54838015_54838197 0.16 Gm16250
 predicted gene 16250
 2798
 0.2
chr10_99267189_99269284 0.16 Gm48089
 predicted gene, 48089
 340
 0.78
chr8_123100430_123100798 0.16 Rpl13
 ribosomal protein L13
 1736
 0.17
chr4_119076605_119076792 0.16 Gm12866
 predicted gene 12866
 7587
 0.12
chr10_84457678_84458129 0.16 Gm47962
 predicted gene, 47962
 17077
 0.12
chr13_9114890_9115041 0.16 Larp4b
 La ribonucleoprotein domain family, member 4B
 20983
 0.14
chr11_114793014_114793463 0.16 Btbd17
 BTB (POZ) domain containing 17
 2635
 0.19
chr14_28508967_28511864 0.16 Wnt5a
 wingless-type MMTV integration site family, member 5A
 203
 0.89
chrX_136822812_136823259 0.16 Plp1
 proteolipid protein (myelin) 1
 245
 0.88
chr1_193175099_193175314 0.16 A130010J15Rik
 RIKEN cDNA A130010J15 gene
 1462
 0.25
chr3_108410436_108412210 0.16 Celsr2
 cadherin, EGF LAG seven-pass G-type receptor 2
 4229
 0.11
chr11_54598816_54599372 0.16 Rapgef6
 Rap guanine nucleotide exchange factor (GEF) 6
 2920
 0.29
chr19_53059154_53059713 0.16 1700054A03Rik
 RIKEN cDNA 1700054A03 gene
 16785
 0.15
chrX_53233797_53233998 0.16 Plac1
 placental specific protein 1
 6214
 0.18
chr7_80398560_80398838 0.15 Furin
 furin (paired basic amino acid cleaving enzyme)
 770
 0.47
chr16_20713164_20713474 0.15 Clcn2
 chloride channel, voltage-sensitive 2
 349
 0.71
chr2_65929929_65930575 0.15 Csrnp3
 cysteine-serine-rich nuclear protein 3
 115
 0.97
chr8_65966341_65967718 0.15 Marchf1
 membrane associated ring-CH-type finger 1
 128
 0.97
chr18_68398281_68398432 0.15 Mc2r
 melanocortin 2 receptor
 30964
 0.15
chr17_32334810_32334961 0.15 Akap8l
 A kinase (PRKA) anchor protein 8-like
 405
 0.76
chr12_11880981_11881577 0.15 Tubb2a-ps2
 tubulin, beta 2a, pseudogene 2
 1384
 0.49
chr15_98977285_98979178 0.15 4930578M01Rik
 RIKEN cDNA 4930578M01 gene
 5117
 0.09
chr9_55043837_55044704 0.15 Chrnb4
 cholinergic receptor, nicotinic, beta polypeptide 4
 4509
 0.13
chr4_155886040_155886274 0.15 Ints11
 integrator complex subunit 11
 1622
 0.16
chr5_115953777_115953928 0.15 Cit
 citron
 2762
 0.23
chr16_91685571_91685880 0.15 Donson
 downstream neighbor of SON
 1290
 0.29
chr2_167777077_167778323 0.15 Gm14321
 predicted gene 14321
 164
 0.94
chr7_99368824_99368975 0.15 Gdpd5
 glycerophosphodiester phosphodiesterase domain containing 5
 12515
 0.14
chr10_128504713_128504957 0.15 Myl6b
 myosin, light polypeptide 6B
 6150
 0.07
chr3_17799177_17799545 0.15 Mir124-2hg
 Mir124-2 host gene (non-protein coding)
 3617
 0.21
chr5_136989551_136989702 0.15 Plod3
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
 680
 0.41
chr10_130276309_130276802 0.15 Neurod4
 neurogenic differentiation 4
 3685
 0.2
chr11_69399334_69402458 0.15 Kdm6bos
 KDM1 lysine (K)-specific demethylase 6B, opposite strand
 617
 0.47
chr8_110924044_110924195 0.15 Gm26132
 predicted gene, 26132
 1003
 0.38
chr8_23043503_23044627 0.15 Ank1
 ankyrin 1, erythroid
 8834
 0.18
chr4_46255563_46255724 0.15 Gm12444
 predicted gene 12444
 11753
 0.15
chr1_132317853_132318004 0.15 Nuak2
 NUAK family, SNF1-like kinase, 2
 1763
 0.24
chr11_118906363_118906514 0.15 Rbfox3
 RNA binding protein, fox-1 homolog (C. elegans) 3
 1567
 0.39
chr13_99594358_99594644 0.15 Gm47158
 predicted gene, 47158
 33059
 0.15
chr1_75277211_75278430 0.15 Resp18
 regulated endocrine-specific protein 18
 464
 0.62
chr12_29537800_29538885 0.15 Myt1l
 myelin transcription factor 1-like
 3120
 0.28
chr10_6788358_6789268 0.15 Oprm1
 opioid receptor, mu 1
 4
 0.99

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.2 GO:0072309 mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.1 0.1 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.1 0.2 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.2 GO:0097476 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1 0.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0061205 paramesonephric duct development(GO:0061205)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0000087 mitotic M phase(GO:0000087)
0.0 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.0 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:1901874 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.0 GO:0048880 sensory system development(GO:0048880)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.1 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.0 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
0.0 0.0 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0 0.0 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.0 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.0 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.0 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0009071 serine family amino acid catabolic process(GO:0009071)
0.0 0.0 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.0 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.0 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.0 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:0042402 cellular biogenic amine catabolic process(GO:0042402)
0.0 0.0 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.0 GO:0019230 proprioception(GO:0019230)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.0 GO:0009310 amine catabolic process(GO:0009310)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.0 GO:1990696 USH2 complex(GO:1990696)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix