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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Tbx4

Z-value: 0.22

Motif logo

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Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
Tbx4
ENSMUSG00000000094.6 T-box 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_85894577_85895744Tbx416050.3589530.612.3e-07Click!
chr11_85894276_85894531Tbx423620.2689910.504.0e-05Click!
chr11_85888239_85889268Tbx413100.4133540.462.1e-04Click!
chr11_85889787_85891444Tbx45520.7456850.435.2e-04Click!
chr11_85892296_85892447Tbx423080.2704500.436.5e-04Click!

Activity of the Tbx4 motif across conditions

Conditions sorted by the z-value of the Tbx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_163395773_163396078 0.29 Jph2
 junctophilin 2
 2024
 0.24
chr2_163396102_163396417 0.27 Jph2
 junctophilin 2
 1690
 0.28
chr3_30546274_30547260 0.25 Mecom
 MDS1 and EVI1 complex locus
 1241
 0.35
chr9_119962629_119963694 0.25 Ttc21a
 tetratricopeptide repeat domain 21A
 1543
 0.24
chr1_34116331_34116653 0.25 Mir6896
 microRNA 6896
 867
 0.57
chr3_19646421_19646748 0.22 Trim55
 tripartite motif-containing 55
 2076
 0.26
chr9_99709458_99709950 0.21 Cldn18
 claudin 18
 305
 0.84
chr1_51291546_51292409 0.20 Cavin2
 caveolae associated 2
 2851
 0.27
chr13_63241575_63242090 0.20 Aopep
 aminopeptidase O
 1724
 0.2
chr16_44015370_44016774 0.20 Gramd1c
 GRAM domain containing 1C
 364
 0.83
chr12_103336858_103338251 0.20 Gm15523
 predicted gene 15523
 648
 0.43
chr8_57324709_57326732 0.19 Hand2os1
 Hand2, opposite strand 1
 1487
 0.3
chr16_36989294_36990265 0.19 Fbxo40
 F-box protein 40
 688
 0.6
chr8_25027794_25028434 0.19 Gm16933
 predicted gene, 16933
 8938
 0.12
chr2_91120847_91121416 0.19 Mybpc3
 myosin binding protein C, cardiac
 2987
 0.16
chr3_155054087_155054557 0.19 Tnni3k
 TNNI3 interacting kinase
 1028
 0.55
chr11_74526613_74527288 0.18 Rap1gap2
 RAP1 GTPase activating protein 2
 4199
 0.25
chr17_81737002_81738450 0.18 Slc8a1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 651
 0.81
chr8_61901105_61901625 0.17 Palld
 palladin, cytoskeletal associated protein
 1304
 0.42
chr9_44069968_44070511 0.17 Usp2
 ubiquitin specific peptidase 2
 796
 0.33
chr11_95841518_95842457 0.16 Abi3
 ABI gene family, member 3
 111
 0.73
chr8_27261786_27261937 0.16 Eif4ebp1
 eukaryotic translation initiation factor 4E binding protein 1
 1532
 0.26
chr1_98132044_98132246 0.16 1810006J02Rik
 RIKEN cDNA 1810006J02 gene
 678
 0.7
chr2_26585065_26586013 0.16 Egfl7
 EGF-like domain 7
 1091
 0.24
chr11_99042414_99042858 0.15 Igfbp4
 insulin-like growth factor binding protein 4
 450
 0.73
chr13_46423537_46423785 0.15 Rbm24
 RNA binding motif protein 24
 1839
 0.41
chr9_45934543_45935100 0.15 Tagln
 transgelin
 753
 0.43
chr6_112728907_112729181 0.15 Rad18
 RAD18 E3 ubiquitin protein ligase
 32358
 0.16
chr6_4005591_4005747 0.14 Gng11
 guanine nucleotide binding protein (G protein), gamma 11
 1765
 0.31
chr16_95703800_95705386 0.14 Ets2
 E26 avian leukemia oncogene 2, 3' domain
 1746
 0.39
chr2_92140355_92141595 0.14 Phf21a
 PHD finger protein 21A
 43131
 0.11
chr15_3580312_3581004 0.14 Ghr
 growth hormone receptor
 1184
 0.57
chr2_32318746_32319267 0.14 Mir199b
 microRNA 199b
 546
 0.42
chr18_35120289_35121263 0.14 Ctnna1
 catenin (cadherin associated protein), alpha 1
 1334
 0.45
chr3_138067510_138069146 0.13 Gm5105
 predicted gene 5105
 940
 0.46
chr9_123480978_123481680 0.13 Limd1
 LIM domains containing 1
 719
 0.66
chr5_134745620_134746234 0.13 Gm30003
 predicted gene, 30003
 1115
 0.35
chr5_147723576_147724353 0.13 Flt1
 FMS-like tyrosine kinase 1
 2024
 0.35
chr12_84643018_84643308 0.13 Vrtn
 vertebrae development associated
 267
 0.89
chr7_140954618_140955957 0.13 Gm45717
 predicted gene 45717
 650
 0.32
chr15_12010211_12011091 0.13 Sub1
 SUB1 homolog, transcriptional regulator
 13668
 0.16
chr2_145787122_145787273 0.13 Rin2
 Ras and Rab interactor 2
 1035
 0.61
chr1_153329741_153330128 0.13 Lamc1
 laminin, gamma 1
 2852
 0.24
chr13_23913630_23913830 0.12 Slc17a4
 solute carrier family 17 (sodium phosphate), member 4
 1238
 0.27
chr8_57340613_57341952 0.12 5033428I22Rik
 RIKEN cDNA 5033428I22 gene
 482
 0.73
chr19_53557067_53557881 0.12 Gm50394
 predicted gene, 50394
 27819
 0.11
chr16_87553258_87554074 0.12 Map3k7cl
 Map3k7 C-terminal like
 336
 0.84
chr2_35627849_35628114 0.12 Dab2ip
 disabled 2 interacting protein
 5821
 0.24
chr10_22813360_22814229 0.12 Gm10824
 predicted gene 10824
 1955
 0.28
chr5_75152837_75154692 0.12 Gm42802
 predicted gene 42802
 111
 0.58
chr10_7831857_7832952 0.12 Zc3h12d
 zinc finger CCCH type containing 12D
 66
 0.95
chr10_120900758_120900909 0.12 Gm4473
 predicted gene 4473
 1676
 0.25
chr14_62798730_62799095 0.12 Gm18146
 predicted gene, 18146
 19215
 0.12
chr8_104101710_104103631 0.12 Cdh5
 cadherin 5
 1045
 0.43
chr11_54962647_54963034 0.12 Tnip1
 TNFAIP3 interacting protein 1
 69
 0.97
chr10_127749619_127751660 0.12 Gpr182
 G protein-coupled receptor 182
 1093
 0.28
chr7_130576739_130577783 0.12 Tacc2
 transforming, acidic coiled-coil containing protein 2
 177
 0.94
chr3_60504423_60505028 0.12 Mbnl1
 muscleblind like splicing factor 1
 3447
 0.29
chr2_181241290_181242534 0.11 Helz2
 helicase with zinc finger 2, transcriptional coactivator
 51
 0.95
chr14_26439572_26439816 0.11 Slmap
 sarcolemma associated protein
 473
 0.78
chr14_101510884_101511350 0.11 Tbc1d4
 TBC1 domain family, member 4
 3791
 0.3
chr12_82122852_82123243 0.11 n-R5s62
 nuclear encoded rRNA 5S 62
 27421
 0.18
chr1_74748322_74749490 0.11 Prkag3
 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
 2
 0.96
chr15_101411658_101413570 0.11 Krt7
 keratin 7
 165
 0.64
chr4_141302549_141302700 0.11 Epha2
 Eph receptor A2
 217
 0.88
chr9_44087058_44087369 0.11 Usp2
 ubiquitin specific peptidase 2
 23
 0.93
chr13_41345830_41346374 0.11 Nedd9
 neural precursor cell expressed, developmentally down-regulated gene 9
 13145
 0.14
chr5_32990256_32991187 0.11 Gm43693
 predicted gene 43693
 6151
 0.16
chr13_102036243_102036435 0.11 Gm38133
 predicted gene, 38133
 79696
 0.1
chr12_117200442_117200898 0.11 Gm10421
 predicted gene 10421
 49019
 0.16
chr8_41040672_41042201 0.11 Mtus1
 mitochondrial tumor suppressor 1
 430
 0.76
chr15_98605967_98606147 0.11 Adcy6
 adenylate cyclase 6
 1231
 0.27
chr14_49244860_49245366 0.11 ccdc198
 coiled-coil domain containing 198
 284
 0.89
chr7_16892200_16892882 0.11 Gng8
 guanine nucleotide binding protein (G protein), gamma 8
 220
 0.83
chr9_55283384_55284127 0.11 Nrg4
 neuregulin 4
 130
 0.96
chr14_49794107_49794296 0.11 Gm22989
 predicted gene, 22989
 5917
 0.14
chr6_115984719_115988278 0.11 Plxnd1
 plexin D1
 8507
 0.15
chr16_58685640_58686063 0.11 Cpox
 coproporphyrinogen oxidase
 7995
 0.13
chr8_33916300_33917561 0.11 Rbpms
 RNA binding protein gene with multiple splicing
 12346
 0.17
chr19_56120628_56120882 0.11 Gm31912
 predicted gene, 31912
 14445
 0.24
chr6_51173127_51174365 0.10 Mir148a
 microRNA 148a
 96164
 0.07
chr2_144676648_144676927 0.10 Dtd1
 D-tyrosyl-tRNA deacylase 1
 1311
 0.47
chr11_63834406_63834560 0.10 Hmgb1-ps3
 high mobility group box 1, pseudogene 3
 12335
 0.21
chr3_116127845_116129091 0.10 Gm43109
 predicted gene 43109
 17
 0.88
chrX_159945522_159946439 0.10 Sh3kbp1
 SH3-domain kinase binding protein 1
 2962
 0.3
chr13_46424277_46424435 0.10 Rbm24
 RNA binding motif protein 24
 2534
 0.34
chr2_27079055_27080577 0.10 Adamtsl2
 ADAMTS-like 2
 437
 0.73
chr5_123318053_123318557 0.10 Gm15857
 predicted gene 15857
 7981
 0.1
chr3_50816196_50816734 0.10 Gm24503
 predicted gene, 24503
 22250
 0.21
chr3_49753928_49755610 0.10 Pcdh18
 protocadherin 18
 695
 0.72
chr5_137349923_137351747 0.10 Ephb4
 Eph receptor B4
 322
 0.77
chr10_18432775_18433290 0.10 Nhsl1
 NHS-like 1
 25357
 0.21
chr7_19011655_19012657 0.10 Irf2bp1
 interferon regulatory factor 2 binding protein 1
 8112
 0.07
chr13_21996613_21997784 0.10 Prss16
 protease, serine 16 (thymus)
 8024
 0.06
chr1_61850467_61850728 0.10 Pard3bos1
 par-3 family cell polarity regulator beta, opposite strand 1
 865
 0.67
chr3_131156467_131156618 0.10 Gm42449
 predicted gene 42449
 19757
 0.17
chr3_142474143_142474633 0.10 Gbp5
 guanylate binding protein 5
 19590
 0.18
chr10_62843668_62844437 0.10 Gm48353
 predicted gene, 48353
 15942
 0.11
chr3_94372701_94373986 0.10 Rorc
 RAR-related orphan receptor gamma
 549
 0.5
chr2_21034615_21035123 0.10 Gm13376
 predicted gene 13376
 62230
 0.1
chr5_101239366_101239752 0.10 Cycs-ps2
 cytochrome c, pseudogene 2
 66019
 0.13
chr9_32146234_32146589 0.10 Arhgap32
 Rho GTPase activating protein 32
 16841
 0.17
chr8_54571415_54571982 0.10 Asb5
 ankyrin repeat and SOCs box-containing 5
 272
 0.9
chr7_44478079_44478838 0.10 5430431A17Rik
 RIKEN cDNA 5430431A17 gene
 4920
 0.07
chr3_89832920_89834058 0.10 She
 src homology 2 domain-containing transforming protein E
 2119
 0.21
chr12_12904321_12905106 0.10 4930519A11Rik
 RIKEN cDNA 4930519A11 gene
 163
 0.93
chr2_166412306_166412566 0.10 Gm14268
 predicted gene 14268
 14249
 0.21
chr3_98280396_98280830 0.10 Hmgcs2
 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
 178
 0.93
chr6_124925245_124926316 0.10 Mlf2
 myeloid leukemia factor 2
 5606
 0.08
chr8_84021064_84022448 0.10 Palm3
 paralemmin 3
 285
 0.75
chr18_53466213_53466522 0.09 Prdm6
 PR domain containing 6
 1851
 0.45
chr4_117391533_117392402 0.09 Rnf220
 ring finger protein 220
 16510
 0.16
chr2_120268555_120268972 0.09 Pla2g4d
 phospholipase A2, group IVD
 20434
 0.13
chr13_113100448_113100599 0.09 Gzma
 granzyme A
 448
 0.7
chrX_152768117_152768457 0.09 Shroom2
 shroom family member 2
 1174
 0.51
chr13_51646613_51647088 0.09 Gm22806
 predicted gene, 22806
 1349
 0.33
chr19_6447935_6448212 0.09 Nrxn2
 neurexin II
 1775
 0.22
chr17_86754057_86754608 0.09 Epas1
 endothelial PAS domain protein 1
 632
 0.71
chr5_100214874_100215472 0.09 2310034O05Rik
 RIKEN cDNA 2310034O05 gene
 4465
 0.21
chr10_76798931_76799264 0.09 Pcbp3
 poly(rC) binding protein 3
 1233
 0.5
chr17_69120419_69121537 0.09 Epb41l3
 erythrocyte membrane protein band 4.1 like 3
 6022
 0.31
chr8_3568500_3569092 0.09 Rps23rg1
 ribosomal protein S23, retrogene 1
 798
 0.43
chr1_189782721_189783385 0.09 Ptpn14
 protein tyrosine phosphatase, non-receptor type 14
 3583
 0.24
chr8_92265739_92266030 0.09 Gm45334
 predicted gene 45334
 32759
 0.16
chr5_128464543_128464766 0.09 Gm42500
 predicted gene 42500
 15750
 0.15
chr3_98245804_98245958 0.09 Gm42821
 predicted gene 42821
 2718
 0.21
chr5_140890731_140891173 0.09 Card11
 caspase recruitment domain family, member 11
 8747
 0.24
chr1_97975537_97975875 0.09 Pam
 peptidylglycine alpha-amidating monooxygenase
 1362
 0.45
chr3_115712293_115713025 0.09 S1pr1
 sphingosine-1-phosphate receptor 1
 2413
 0.28
chr12_31270509_31272027 0.09 Lamb1
 laminin B1
 5388
 0.14
chr1_74303501_74304573 0.09 Tmbim1
 transmembrane BAX inhibitor motif containing 1
 83
 0.93
chr10_116750858_116751292 0.09 4930579P08Rik
 RIKEN cDNA 4930579P08 gene
 21822
 0.16
chr5_119742473_119742643 0.09 Tbx3os2
 T-box 3, opposite strand 2
 51340
 0.1
chr3_53165376_53165642 0.09 Gm43803
 predicted gene 43803
 52098
 0.09
chr4_133084556_133086193 0.09 Ahdc1
 AT hook, DNA binding motif, containing 1
 19125
 0.17
chr5_29467659_29468760 0.09 Mnx1
 motor neuron and pancreas homeobox 1
 10261
 0.16
chr7_100657972_100658903 0.09 Plekhb1
 pleckstrin homology domain containing, family B (evectins) member 1
 15
 0.96
chr11_78378001_78378152 0.09 Foxn1
 forkhead box N1
 8482
 0.09
chr9_44087472_44088439 0.09 Usp2
 ubiquitin specific peptidase 2
 765
 0.37
chr11_103096614_103097909 0.09 Plcd3
 phospholipase C, delta 3
 4330
 0.13
chr15_59030318_59030922 0.09 Mtss1
 MTSS I-BAR domain containing 1
 9976
 0.21
chr18_16436164_16436577 0.09 Gm7665
 predicted pseudogene 7665
 161426
 0.04
chr18_69118550_69118756 0.09 Gm23536
 predicted gene, 23536
 55467
 0.12
chr4_115088735_115089677 0.09 Pdzk1ip1
 PDZK1 interacting protein 1
 163
 0.94
chr5_101703476_101703804 0.09 9430085M18Rik
 RIKEN cDNA 9430085M18 gene
 54
 0.87
chr5_100844231_100844692 0.09 Gpat3
 glycerol-3-phosphate acyltransferase 3
 1252
 0.27
chr8_57335156_57335307 0.09 Gm34030
 predicted gene, 34030
 646
 0.6
chr10_115817324_115818606 0.09 Tspan8
 tetraspanin 8
 681
 0.78
chr7_102106752_102107605 0.09 Art5
 ADP-ribosyltransferase 5
 2311
 0.16
chr7_19295472_19296203 0.09 Rtn2
 reticulon 2 (Z-band associated protein)
 4768
 0.08
chr8_70493071_70496051 0.09 Crlf1
 cytokine receptor-like factor 1
 1200
 0.25
chr5_120476252_120476535 0.09 Sds
 serine dehydratase
 133
 0.92
chr11_114478869_114479221 0.08 4932435O22Rik
 RIKEN cDNA 4932435O22 gene
 30185
 0.2
chr3_82141940_82142375 0.08 Gucy1a1
 guanylate cyclase 1, soluble, alpha 1
 2916
 0.3
chr2_32608081_32609404 0.08 St6galnac6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 25
 0.94
chr15_103383151_103383913 0.08 Gm37322
 predicted gene, 37322
 5461
 0.13
chr9_68234867_68235111 0.08 Gm28195
 predicted gene 28195
 40
 0.98
chr2_156717216_156718150 0.08 Dlgap4
 DLG associated protein 4
 2889
 0.18
chr16_91917498_91918270 0.08 Gm25245
 predicted gene, 25245
 3531
 0.14
chr6_34355142_34355293 0.08 Akr1b8
 aldo-keto reductase family 1, member B8
 898
 0.49
chr8_126587716_126588216 0.08 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 6020
 0.24
chr2_91125839_91126091 0.08 Mybpc3
 myosin binding protein C, cardiac
 7821
 0.12
chrX_48400504_48400994 0.08 Bcorl1
 BCL6 co-repressor-like 1
 31481
 0.15
chr11_18873955_18876215 0.08 8430419K02Rik
 RIKEN cDNA 8430419K02 gene
 776
 0.61
chr2_35623965_35624326 0.08 Dab2ip
 disabled 2 interacting protein
 1985
 0.37
chr18_68058494_68058645 0.08 Gm41764
 predicted gene, 41764
 59805
 0.12
chr6_140888560_140888983 0.08 Gm30524
 predicted gene, 30524
 66838
 0.11
chr5_96920446_96920776 0.08 Gm8013
 predicted gene 8013
 661
 0.48
chr7_25613317_25613468 0.08 Erich4
 glutamate rich 4
 2500
 0.13
chr8_122285085_122285236 0.08 Zfpm1
 zinc finger protein, multitype 1
 3019
 0.21
chr10_13092588_13092795 0.08 Plagl1
 pleiomorphic adenoma gene-like 1
 1678
 0.4
chr5_103829138_103829289 0.08 Aff1
 AF4/FMR2 family, member 1
 44854
 0.11
chr6_113690658_113691420 0.08 Irak2
 interleukin-1 receptor-associated kinase 2
 294
 0.72
chr16_34056924_34057075 0.08 Kalrn
 kalirin, RhoGEF kinase
 38988
 0.16
chr9_111119102_111119253 0.08 Lrrfip2
 leucine rich repeat (in FLII) interacting protein 2
 252
 0.9
chr17_56134469_56135201 0.08 Sema6b
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 992
 0.33
chr17_78676930_78677295 0.08 Strn
 striatin, calmodulin binding protein
 7240
 0.21
chr6_129183729_129184848 0.08 Clec2d
 C-type lectin domain family 2, member d
 3673
 0.14
chr4_19576297_19576523 0.08 Rmdn1
 regulator of microtubule dynamics 1
 1203
 0.48
chr15_31396603_31396758 0.08 Gm49300
 predicted gene, 49300
 28318
 0.11
chr15_57793060_57793483 0.08 9330154K18Rik
 RIKEN cDNA 9330154K18 gene
 54605
 0.12
chr6_52965535_52965952 0.08 Gm26215
 predicted gene, 26215
 44789
 0.14
chr10_118839718_118840226 0.08 Gm47434
 predicted gene, 47434
 4866
 0.15
chr1_133418145_133418838 0.08 Sox13
 SRY (sex determining region Y)-box 13
 5886
 0.2
chr8_69023381_69023534 0.08 Gm15716
 predicted gene 15716
 21297
 0.15
chr2_158142922_158143689 0.08 Tgm2
 transglutaminase 2, C polypeptide
 3061
 0.21
chr7_4515813_4516413 0.08 Tnnt1
 troponin T1, skeletal, slow
 109
 0.91
chr2_77169306_77170885 0.08 Ccdc141
 coiled-coil domain containing 141
 481
 0.83
chr3_30360581_30360732 0.08 Gm38362
 predicted gene, 38362
 86271
 0.07
chr1_34105041_34105192 0.08 Mir6896
 microRNA 6896
 12243
 0.17
chr12_83770139_83771096 0.08 Papln
 papilin, proteoglycan-like sulfated glycoprotein
 6955
 0.12
chr14_69053224_69053475 0.08 Gm41192
 predicted gene, 41192
 23697
 0.16
chr14_20929965_20930649 0.08 Vcl
 vinculin
 909
 0.62
chr12_111416717_111418003 0.08 Exoc3l4
 exocyst complex component 3-like 4
 70
 0.96
chr16_85546798_85547372 0.08 Cyyr1
 cysteine and tyrosine-rich protein 1
 3332
 0.28
chr17_72937316_72937687 0.08 Lbh
 limb-bud and heart
 16313
 0.22
chr11_80508926_80509274 0.08 C030013C21Rik
 RIKEN cDNA C030013C21 gene
 6
 0.98
chr19_32322600_32322981 0.08 Sgms1
 sphingomyelin synthase 1
 439
 0.87
chr13_69460904_69461114 0.08 Gm48676
 predicted gene, 48676
 52991
 0.09
chr7_19163884_19165719 0.08 Gipr
 gastric inhibitory polypeptide receptor
 293
 0.77

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.2 GO:0086064 cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0031034 myosin filament assembly(GO:0031034)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.0 GO:0002339 B cell selection(GO:0002339)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.0 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.0 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.1 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0042731 PH domain binding(GO:0042731)
0.0 0.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling