Project
ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tbx4

Z-value: 0.22

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Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
Tbx4
ENSMUSG00000000094.6 Tbx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Tbx4chr11_85894577_8589574416050.3589530.612.3e-07Click!
Tbx4chr11_85894276_8589453123620.2689910.504.0e-05Click!
Tbx4chr11_85888239_8588926813100.4133540.462.1e-04Click!
Tbx4chr11_85889787_858914445520.7456850.435.2e-04Click!
Tbx4chr11_85892296_8589244723080.2704500.436.5e-04Click!

Activity of the Tbx4 motif across conditions

Conditions sorted by the z-value of the Tbx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_163395773_163396078 0.29 Jph2
 junctophilin 2
 2024
 0.24
chr2_163396102_163396417 0.27 Jph2
 junctophilin 2
 1690
 0.28
chr3_30546274_30547260 0.25 Mecom
 MDS1 and EVI1 complex locus
 1241
 0.35
chr9_119962629_119963694 0.25 Ttc21a
 tetratricopeptide repeat domain 21A
 1543
 0.24
chr1_34116331_34116653 0.25 Mir6896
 microRNA 6896
 867
 0.57
chr3_19646421_19646748 0.22 Trim55
 tripartite motif-containing 55
 2076
 0.26
chr9_99709458_99709950 0.21 Cldn18
 claudin 18
 305
 0.84
chr1_51291546_51292409 0.20 Cavin2
 caveolae associated 2
 2851
 0.27
chr13_63241575_63242090 0.20 Aopep
 aminopeptidase O
 1724
 0.2
chr16_44015370_44016774 0.20 Gramd1c
 GRAM domain containing 1C
 364
 0.83
chr12_103336858_103338251 0.20 Gm15523
 predicted gene 15523
 648
 0.43
chr8_57324709_57326732 0.19 Hand2os1
 Hand2, opposite strand 1
 1487
 0.3
chr16_36989294_36990265 0.19 Fbxo40
 F-box protein 40
 688
 0.6
chr8_25027794_25028434 0.19 Gm16933
 predicted gene, 16933
 8938
 0.12
chr2_91120847_91121416 0.19 Mybpc3
 myosin binding protein C, cardiac
 2987
 0.16
chr3_155054087_155054557 0.19 Tnni3k
 TNNI3 interacting kinase
 1028
 0.55
chr11_74526613_74527288 0.18 Rap1gap2
 RAP1 GTPase activating protein 2
 4199
 0.25
chr17_81737002_81738450 0.18 Slc8a1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 651
 0.81
chr8_61901105_61901625 0.17 Palld
 palladin, cytoskeletal associated protein
 1304
 0.42
chr9_44069968_44070511 0.17 Usp2
 ubiquitin specific peptidase 2
 796
 0.33
chr11_95841518_95842457 0.16 Abi3
 ABI gene family, member 3
 111
 0.73
chr8_27261786_27261937 0.16 Eif4ebp1
 eukaryotic translation initiation factor 4E binding protein 1
 1532
 0.26
chr1_98132044_98132246 0.16 1810006J02Rik
 RIKEN cDNA 1810006J02 gene
 678
 0.7
chr2_26585065_26586013 0.16 Egfl7
 EGF-like domain 7
 1091
 0.24
chr11_99042414_99042858 0.15 Igfbp4
 insulin-like growth factor binding protein 4
 450
 0.73
chr13_46423537_46423785 0.15 Rbm24
 RNA binding motif protein 24
 1839
 0.41
chr9_45934543_45935100 0.15 Tagln
 transgelin
 753
 0.43
chr6_112728907_112729181 0.15 Rad18
 RAD18 E3 ubiquitin protein ligase
 32358
 0.16
chr6_4005591_4005747 0.14 Gng11
 guanine nucleotide binding protein (G protein), gamma 11
 1765
 0.31
chr16_95703800_95705386 0.14 Ets2
 E26 avian leukemia oncogene 2, 3' domain
 1746
 0.39
chr2_92140355_92141595 0.14 Phf21a
 PHD finger protein 21A
 43131
 0.11
chr15_3580312_3581004 0.14 Ghr
 growth hormone receptor
 1184
 0.57
chr2_32318746_32319267 0.14 Mir199b
 microRNA 199b
 546
 0.42
chr18_35120289_35121263 0.14 Ctnna1
 catenin (cadherin associated protein), alpha 1
 1334
 0.45
chr3_138067510_138069146 0.13 Gm5105
 predicted gene 5105
 940
 0.46
chr9_123480978_123481680 0.13 Limd1
 LIM domains containing 1
 719
 0.66
chr5_134745620_134746234 0.13 Gm30003
 predicted gene, 30003
 1115
 0.35
chr5_147723576_147724353 0.13 Flt1
 FMS-like tyrosine kinase 1
 2024
 0.35
chr12_84643018_84643308 0.13 Vrtn
 vertebrae development associated
 267
 0.89
chr7_140954618_140955957 0.13 Gm45717
 predicted gene 45717
 650
 0.32
chr15_12010211_12011091 0.13 Sub1
 SUB1 homolog, transcriptional regulator
 13668
 0.16
chr2_145787122_145787273 0.13 Rin2
 Ras and Rab interactor 2
 1035
 0.61
chr1_153329741_153330128 0.13 Lamc1
 laminin, gamma 1
 2852
 0.24
chr13_23913630_23913830 0.12 Slc17a4
 solute carrier family 17 (sodium phosphate), member 4
 1238
 0.27
chr8_57340613_57341952 0.12 5033428I22Rik
 RIKEN cDNA 5033428I22 gene
 482
 0.73
chr19_53557067_53557881 0.12 Gm50394
 predicted gene, 50394
 27819
 0.11
chr16_87553258_87554074 0.12 Map3k7cl
 Map3k7 C-terminal like
 336
 0.84
chr2_35627849_35628114 0.12 Dab2ip
 disabled 2 interacting protein
 5821
 0.24
chr10_22813360_22814229 0.12 Gm10824
 predicted gene 10824
 1955
 0.28
chr5_75152837_75154692 0.12 Gm42802
 predicted gene 42802
 111
 0.58
chr10_7831857_7832952 0.12 Zc3h12d
 zinc finger CCCH type containing 12D
 66
 0.95
chr10_120900758_120900909 0.12 Gm4473
 predicted gene 4473
 1676
 0.25
chr14_62798730_62799095 0.12 Gm18146
 predicted gene, 18146
 19215
 0.12
chr8_104101710_104103631 0.12 Cdh5
 cadherin 5
 1045
 0.43
chr11_54962647_54963034 0.12 Tnip1
 TNFAIP3 interacting protein 1
 69
 0.97
chr10_127749619_127751660 0.12 Gpr182
 G protein-coupled receptor 182
 1093
 0.28
chr7_130576739_130577783 0.12 Tacc2
 transforming, acidic coiled-coil containing protein 2
 177
 0.94
chr3_60504423_60505028 0.12 Mbnl1
 muscleblind like splicing factor 1
 3447
 0.29
chr2_181241290_181242534 0.11 Helz2
 helicase with zinc finger 2, transcriptional coactivator
 51
 0.95
chr14_26439572_26439816 0.11 Slmap
 sarcolemma associated protein
 473
 0.78
chr14_101510884_101511350 0.11 Tbc1d4
 TBC1 domain family, member 4
 3791
 0.3
chr12_82122852_82123243 0.11 n-R5s62
 nuclear encoded rRNA 5S 62
 27421
 0.18
chr1_74748322_74749490 0.11 Prkag3
 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
 2
 0.96
chr15_101411658_101413570 0.11 Krt7
 keratin 7
 165
 0.64
chr4_141302549_141302700 0.11 Epha2
 Eph receptor A2
 217
 0.88
chr9_44087058_44087369 0.11 Usp2
 ubiquitin specific peptidase 2
 23
 0.93
chr13_41345830_41346374 0.11 Nedd9
 neural precursor cell expressed, developmentally down-regulated gene 9
 13145
 0.14
chr5_32990256_32991187 0.11 Gm43693
 predicted gene 43693
 6151
 0.16
chr13_102036243_102036435 0.11 Gm38133
 predicted gene, 38133
 79696
 0.1
chr12_117200442_117200898 0.11 Gm10421
 predicted gene 10421
 49019
 0.16
chr8_41040672_41042201 0.11 Mtus1
 mitochondrial tumor suppressor 1
 430
 0.76
chr15_98605967_98606147 0.11 Adcy6
 adenylate cyclase 6
 1231
 0.27
chr14_49244860_49245366 0.11 ccdc198
 coiled-coil domain containing 198
 284
 0.89
chr7_16892200_16892882 0.11 Gng8
 guanine nucleotide binding protein (G protein), gamma 8
 220
 0.83
chr9_55283384_55284127 0.11 Nrg4
 neuregulin 4
 130
 0.96
chr14_49794107_49794296 0.11 Gm22989
 predicted gene, 22989
 5917
 0.14
chr6_115984719_115988278 0.11 Plxnd1
 plexin D1
 8507
 0.15
chr16_58685640_58686063 0.11 Cpox
 coproporphyrinogen oxidase
 7995
 0.13
chr8_33916300_33917561 0.11 Rbpms
 RNA binding protein gene with multiple splicing
 12346
 0.17
chr19_56120628_56120882 0.11 Gm31912
 predicted gene, 31912
 14445
 0.24
chr6_51173127_51174365 0.10 Mir148a
 microRNA 148a
 96164
 0.07
chr2_144676648_144676927 0.10 Dtd1
 D-tyrosyl-tRNA deacylase 1
 1311
 0.47
chr11_63834406_63834560 0.10 Hmgb1-ps3
 high mobility group box 1, pseudogene 3
 12335
 0.21
chr3_116127845_116129091 0.10 Gm43109
 predicted gene 43109
 17
 0.88
chrX_159945522_159946439 0.10 Sh3kbp1
 SH3-domain kinase binding protein 1
 2962
 0.3
chr13_46424277_46424435 0.10 Rbm24
 RNA binding motif protein 24
 2534
 0.34
chr2_27079055_27080577 0.10 Adamtsl2
 ADAMTS-like 2
 437
 0.73
chr5_123318053_123318557 0.10 Gm15857
 predicted gene 15857
 7981
 0.1
chr3_50816196_50816734 0.10 Gm24503
 predicted gene, 24503
 22250
 0.21
chr3_49753928_49755610 0.10 Pcdh18
 protocadherin 18
 695
 0.72
chr5_137349923_137351747 0.10 Ephb4
 Eph receptor B4
 322
 0.77
chr10_18432775_18433290 0.10 Nhsl1
 NHS-like 1
 25357
 0.21
chr7_19011655_19012657 0.10 Irf2bp1
 interferon regulatory factor 2 binding protein 1
 8112
 0.07
chr13_21996613_21997784 0.10 Prss16
 protease, serine 16 (thymus)
 8024
 0.06
chr1_61850467_61850728 0.10 Pard3bos1
 par-3 family cell polarity regulator beta, opposite strand 1
 865
 0.67
chr3_131156467_131156618 0.10 Gm42449
 predicted gene 42449
 19757
 0.17
chr3_142474143_142474633 0.10 Gbp5
 guanylate binding protein 5
 19590
 0.18
chr10_62843668_62844437 0.10 Gm48353
 predicted gene, 48353
 15942
 0.11
chr3_94372701_94373986 0.10 Rorc
 RAR-related orphan receptor gamma
 549
 0.5
chr2_21034615_21035123 0.10 Gm13376
 predicted gene 13376
 62230
 0.1
chr5_101239366_101239752 0.10 Cycs-ps2
 cytochrome c, pseudogene 2
 66019
 0.13
chr9_32146234_32146589 0.10 Arhgap32
 Rho GTPase activating protein 32
 16841
 0.17
chr8_54571415_54571982 0.10 Asb5
 ankyrin repeat and SOCs box-containing 5
 272
 0.9
chr7_44478079_44478838 0.10 5430431A17Rik
 RIKEN cDNA 5430431A17 gene
 4920
 0.07
chr3_89832920_89834058 0.10 She
 src homology 2 domain-containing transforming protein E
 2119
 0.21
chr12_12904321_12905106 0.10 4930519A11Rik
 RIKEN cDNA 4930519A11 gene
 163
 0.93
chr2_166412306_166412566 0.10 Gm14268
 predicted gene 14268
 14249
 0.21
chr3_98280396_98280830 0.10 Hmgcs2
 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
 178
 0.93
chr6_124925245_124926316 0.10 Mlf2
 myeloid leukemia factor 2
 5606
 0.08
chr8_84021064_84022448 0.10 Palm3
 paralemmin 3
 285
 0.75
chr18_53466213_53466522 0.09 Prdm6
 PR domain containing 6
 1851
 0.45
chr4_117391533_117392402 0.09 Rnf220
 ring finger protein 220
 16510
 0.16
chr2_120268555_120268972 0.09 Pla2g4d
 phospholipase A2, group IVD
 20434
 0.13
chr13_113100448_113100599 0.09 Gzma
 granzyme A
 448
 0.7
chrX_152768117_152768457 0.09 Shroom2
 shroom family member 2
 1174
 0.51
chr13_51646613_51647088 0.09 Gm22806
 predicted gene, 22806
 1349
 0.33
chr19_6447935_6448212 0.09 Nrxn2
 neurexin II
 1775
 0.22
chr17_86754057_86754608 0.09 Epas1
 endothelial PAS domain protein 1
 632
 0.71
chr5_100214874_100215472 0.09 2310034O05Rik
 RIKEN cDNA 2310034O05 gene
 4465
 0.21
chr10_76798931_76799264 0.09 Pcbp3
 poly(rC) binding protein 3
 1233
 0.5
chr17_69120419_69121537 0.09 Epb41l3
 erythrocyte membrane protein band 4.1 like 3
 6022
 0.31
chr8_3568500_3569092 0.09 Rps23rg1
 ribosomal protein S23, retrogene 1
 798
 0.43
chr1_189782721_189783385 0.09 Ptpn14
 protein tyrosine phosphatase, non-receptor type 14
 3583
 0.24
chr8_92265739_92266030 0.09 Gm45334
 predicted gene 45334
 32759
 0.16
chr5_128464543_128464766 0.09 Gm42500
 predicted gene 42500
 15750
 0.15
chr3_98245804_98245958 0.09 Gm42821
 predicted gene 42821
 2718
 0.21
chr5_140890731_140891173 0.09 Card11
 caspase recruitment domain family, member 11
 8747
 0.24
chr1_97975537_97975875 0.09 Pam
 peptidylglycine alpha-amidating monooxygenase
 1362
 0.45
chr3_115712293_115713025 0.09 S1pr1
 sphingosine-1-phosphate receptor 1
 2413
 0.28
chr12_31270509_31272027 0.09 Lamb1
 laminin B1
 5388
 0.14
chr1_74303501_74304573 0.09 Tmbim1
 transmembrane BAX inhibitor motif containing 1
 83
 0.93
chr10_116750858_116751292 0.09 4930579P08Rik
 RIKEN cDNA 4930579P08 gene
 21822
 0.16
chr5_119742473_119742643 0.09 Tbx3os2
 T-box 3, opposite strand 2
 51340
 0.1
chr3_53165376_53165642 0.09 Gm43803
 predicted gene 43803
 52098
 0.09
chr4_133084556_133086193 0.09 Ahdc1
 AT hook, DNA binding motif, containing 1
 19125
 0.17
chr5_29467659_29468760 0.09 Mnx1
 motor neuron and pancreas homeobox 1
 10261
 0.16
chr7_100657972_100658903 0.09 Plekhb1
 pleckstrin homology domain containing, family B (evectins) member 1
 15
 0.96
chr11_78378001_78378152 0.09 Foxn1
 forkhead box N1
 8482
 0.09
chr9_44087472_44088439 0.09 Usp2
 ubiquitin specific peptidase 2
 765
 0.37
chr11_103096614_103097909 0.09 Plcd3
 phospholipase C, delta 3
 4330
 0.13
chr15_59030318_59030922 0.09 Mtss1
 MTSS I-BAR domain containing 1
 9976
 0.21
chr18_16436164_16436577 0.09 Gm7665
 predicted pseudogene 7665
 161426
 0.04
chr18_69118550_69118756 0.09 Gm23536
 predicted gene, 23536
 55467
 0.12
chr4_115088735_115089677 0.09 Pdzk1ip1
 PDZK1 interacting protein 1
 163
 0.94
chr5_101703476_101703804 0.09 9430085M18Rik
 RIKEN cDNA 9430085M18 gene
 54
 0.87
chr5_100844231_100844692 0.09 Gpat3
 glycerol-3-phosphate acyltransferase 3
 1252
 0.27
chr8_57335156_57335307 0.09 Gm34030
 predicted gene, 34030
 646
 0.6
chr10_115817324_115818606 0.09 Tspan8
 tetraspanin 8
 681
 0.78
chr7_102106752_102107605 0.09 Art5
 ADP-ribosyltransferase 5
 2311
 0.16
chr7_19295472_19296203 0.09 Rtn2
 reticulon 2 (Z-band associated protein)
 4768
 0.08
chr8_70493071_70496051 0.09 Crlf1
 cytokine receptor-like factor 1
 1200
 0.25
chr5_120476252_120476535 0.09 Sds
 serine dehydratase
 133
 0.92
chr11_114478869_114479221 0.08 4932435O22Rik
 RIKEN cDNA 4932435O22 gene
 30185
 0.2
chr3_82141940_82142375 0.08 Gucy1a1
 guanylate cyclase 1, soluble, alpha 1
 2916
 0.3
chr2_32608081_32609404 0.08 St6galnac6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 25
 0.94
chr15_103383151_103383913 0.08 Gm37322
 predicted gene, 37322
 5461
 0.13
chr9_68234867_68235111 0.08 Gm28195
 predicted gene 28195
 40
 0.98
chr2_156717216_156718150 0.08 Dlgap4
 DLG associated protein 4
 2889
 0.18
chr16_91917498_91918270 0.08 Gm25245
 predicted gene, 25245
 3531
 0.14
chr6_34355142_34355293 0.08 Akr1b8
 aldo-keto reductase family 1, member B8
 898
 0.49
chr8_126587716_126588216 0.08 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 6020
 0.24
chr2_91125839_91126091 0.08 Mybpc3
 myosin binding protein C, cardiac
 7821
 0.12
chrX_48400504_48400994 0.08 Bcorl1
 BCL6 co-repressor-like 1
 31481
 0.15
chr11_18873955_18876215 0.08 8430419K02Rik
 RIKEN cDNA 8430419K02 gene
 776
 0.61
chr2_35623965_35624326 0.08 Dab2ip
 disabled 2 interacting protein
 1985
 0.37
chr18_68058494_68058645 0.08 Gm41764
 predicted gene, 41764
 59805
 0.12
chr6_140888560_140888983 0.08 Gm30524
 predicted gene, 30524
 66838
 0.11
chr5_96920446_96920776 0.08 Gm8013
 predicted gene 8013
 661
 0.48
chr7_25613317_25613468 0.08 Erich4
 glutamate rich 4
 2500
 0.13
chr8_122285085_122285236 0.08 Zfpm1
 zinc finger protein, multitype 1
 3019
 0.21
chr10_13092588_13092795 0.08 Plagl1
 pleiomorphic adenoma gene-like 1
 1678
 0.4
chr5_103829138_103829289 0.08 Aff1
 AF4/FMR2 family, member 1
 44854
 0.11
chr6_113690658_113691420 0.08 Irak2
 interleukin-1 receptor-associated kinase 2
 294
 0.72
chr16_34056924_34057075 0.08 Kalrn
 kalirin, RhoGEF kinase
 38988
 0.16
chr9_111119102_111119253 0.08 Lrrfip2
 leucine rich repeat (in FLII) interacting protein 2
 252
 0.9
chr17_56134469_56135201 0.08 Sema6b
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 992
 0.33
chr17_78676930_78677295 0.08 Strn
 striatin, calmodulin binding protein
 7240
 0.21
chr6_129183729_129184848 0.08 Clec2d
 C-type lectin domain family 2, member d
 3673
 0.14
chr4_19576297_19576523 0.08 Rmdn1
 regulator of microtubule dynamics 1
 1203
 0.48
chr15_31396603_31396758 0.08 Gm49300
 predicted gene, 49300
 28318
 0.11
chr15_57793060_57793483 0.08 9330154K18Rik
 RIKEN cDNA 9330154K18 gene
 54605
 0.12
chr6_52965535_52965952 0.08 Gm26215
 predicted gene, 26215
 44789
 0.14
chr10_118839718_118840226 0.08 Gm47434
 predicted gene, 47434
 4866
 0.15
chr1_133418145_133418838 0.08 Sox13
 SRY (sex determining region Y)-box 13
 5886
 0.2
chr8_69023381_69023534 0.08 Gm15716
 predicted gene 15716
 21297
 0.15
chr2_158142922_158143689 0.08 Tgm2
 transglutaminase 2, C polypeptide
 3061
 0.21
chr7_4515813_4516413 0.08 Tnnt1
 troponin T1, skeletal, slow
 109
 0.91
chr2_77169306_77170885 0.08 Ccdc141
 coiled-coil domain containing 141
 481
 0.83
chr3_30360581_30360732 0.08 Gm38362
 predicted gene, 38362
 86271
 0.07
chr1_34105041_34105192 0.08 Mir6896
 microRNA 6896
 12243
 0.17
chr12_83770139_83771096 0.08 Papln
 papilin, proteoglycan-like sulfated glycoprotein
 6955
 0.12
chr14_69053224_69053475 0.08 Gm41192
 predicted gene, 41192
 23697
 0.16
chr14_20929965_20930649 0.08 Vcl
 vinculin
 909
 0.62
chr12_111416717_111418003 0.08 Exoc3l4
 exocyst complex component 3-like 4
 70
 0.96
chr16_85546798_85547372 0.08 Cyyr1
 cysteine and tyrosine-rich protein 1
 3332
 0.28
chr17_72937316_72937687 0.08 Lbh
 limb-bud and heart
 16313
 0.22
chr11_80508926_80509274 0.08 C030013C21Rik
 RIKEN cDNA C030013C21 gene
 6
 0.98
chr19_32322600_32322981 0.08 Sgms1
 sphingomyelin synthase 1
 439
 0.87
chr13_69460904_69461114 0.08 Gm48676
 predicted gene, 48676
 52991
 0.09
chr7_19163884_19165719 0.08 Gipr
 gastric inhibitory polypeptide receptor
 293
 0.77

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.2 GO:0086064 cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0031034 myosin filament assembly(GO:0031034)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.0 GO:0002339 B cell selection(GO:0002339)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.0 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.0 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.1 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0042731 PH domain binding(GO:0042731)
0.0 0.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling