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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development

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Results for Tfap2b

Z-value: 1.40

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Transcription factors associated with Tfap2b

Gene Symbol	Gene ID	Gene Info
Tfap2b Ensembl NCBI MGI UniProt	ENSMUSG00000025927.7	transcription factor AP-2 beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_19215607_19218714	Tfap2b	3281	0.253782	0.49	8.3e-05	Click!
chr1_19220175_19220369	Tfap2b	6393	0.208006	0.45	3.6e-04	Click!
chr1_19221721_19222092	Tfap2b	8027	0.200189	0.44	4.3e-04	Click!
chr1_19211267_19211418	Tfap2b	712	0.695958	0.44	4.8e-04	Click!
chr1_19213854_19215338	Tfap2b	717	0.693033	0.42	7.9e-04	Click!

Activity of the Tfap2b motif across conditions

Conditions sorted by the z-value of the Tfap2b motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_12016565_12017148	12.84	Gm18854	predicted gene, 18854	8595	0.06
chr6_3139665_3140541	11.14	Vmn1r261	vomeronasal 1 receptor 261	4451	0.18
chr7_12015381_12015902	10.76	Gm18854	predicted gene, 18854	9810	0.06
chr4_3177527_3177893	10.74	Vmn1r2	vomeronasal 1 receptor 2	5627	0.18
chr4_3178062_3178308	10.12	Vmn1r2	vomeronasal 1 receptor 2	6102	0.18
chr6_3134749_3135336	9.15	Vmn1r261	vomeronasal 1 receptor 261	9512	0.15
chr4_3174860_3175282	7.58	Vmn1r2	vomeronasal 1 receptor 2	2988	0.23
chr6_3133407_3133761	6.23	Vmn1r261	vomeronasal 1 receptor 261	10970	0.15
chr4_3165069_3165416	6.00	Vmn1r2	vomeronasal 1 receptor 2	2078	0.28
chr4_3175732_3175907	5.80	Vmn1r2	vomeronasal 1 receptor 2	3736	0.2
chr18_3114228_3114696	5.14	Vmn1r238	vomeronasal 1 receptor, 238	8950	0.15
chr4_3180418_3180743	5.06	Vmn1r3	vomeronasal 1 receptor 3	4778	0.19
chr6_3133766_3134164	4.89	Vmn1r261	vomeronasal 1 receptor 261	10589	0.15
chr18_3120117_3120268	4.48	Vmn1r238	vomeronasal 1 receptor, 238	3220	0.2
chr18_20622092_20622498	4.41	Gm16090	predicted gene 16090	42965	0.11
chr7_12017388_12017543	4.27	Gm18854	predicted gene, 18854	7986	0.07
chr4_3176014_3176165	4.21	Vmn1r2	vomeronasal 1 receptor 2	4006	0.2
chr6_3133084_3133397	4.02	Vmn1r261	vomeronasal 1 receptor 261	11314	0.15
chr4_3178658_3179000	3.97	Vmn1r3	vomeronasal 1 receptor 3	6529	0.17
chr18_20616785_20616936	3.86	Gm16090	predicted gene 16090	48400	0.1
chr12_67219520_67219941	3.84	Mdga2	MAM domain containing glycosylphosphatidylinositol anchor 2	1312	0.58
chr4_3180151_3180369	3.64	Vmn1r3	vomeronasal 1 receptor 3	5098	0.18
chr15_85674019_85674170	3.16	Lncppara	long noncoding RNA near Ppara	20478	0.13
chr18_3113271_3113666	3.08	Gm50073	predicted gene, 50073	8072	0.15
chr11_80478619_80479391	3.01	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	1949	0.32
chr4_3176287_3176438	2.93	Vmn1r2	vomeronasal 1 receptor 2	4279	0.19
chr18_20617577_20617842	2.71	Gm16090	predicted gene 16090	47551	0.1
chr6_3139267_3139418	2.55	Vmn1r261	vomeronasal 1 receptor 261	5212	0.17
chr10_18470218_18471289	2.54	Nhsl1	NHS-like 1	772	0.72
chr11_44619132_44619686	2.40	Ebf1	early B cell factor 1	1230	0.4
chr18_43391758_43391959	2.37	Dpysl3	dihydropyrimidinase-like 3	1519	0.46
chr7_12014240_12014526	2.33	Vmn1r-ps60	vomeronasal 1 receptor, pseudogene 60	9317	0.06
chr4_152339671_152339875	2.31	Chd5	chromodomain helicase DNA binding protein 5	886	0.45
chr6_3137884_3138147	2.21	Vmn1r261	vomeronasal 1 receptor 261	6539	0.16
chr11_61453075_61454398	2.16	Rnf112	ring finger protein 112	183	0.92
chr8_125897868_125898882	2.16	Pcnx2	pecanex homolog 2	58	0.88
chr2_172040251_172043672	2.14	Cbln4	cerebellin 4 precursor protein	1505	0.35
chr9_91378153_91379783	2.11	Zic4	zinc finger protein of the cerebellum 4	326	0.81
chr11_96271391_96272011	2.10	Hoxb9	homeobox B9	178	0.86
chr3_108153841_108154889	2.05	Gpr61	G protein-coupled receptor 61	517	0.6
chr5_30712882_30713845	1.96	Dpysl5	dihydropyrimidinase-like 5	1462	0.33
chr10_127529755_127530351	1.91	Nxph4	neurexophilin 4	4506	0.11
chr18_20625506_20625801	1.84	Gm16090	predicted gene 16090	39607	0.12
chr4_3177295_3177446	1.82	Vmn1r2	vomeronasal 1 receptor 2	5287	0.18
chr19_45230983_45235468	1.79	Lbx1	ladybird homeobox 1	2587	0.27
chr5_103209022_103210413	1.79	Mapk10	mitogen-activated protein kinase 10	705	0.75
chr7_79535310_79536820	1.78	Gm35040	predicted gene, 35040	22	0.95
chr11_66522535_66522832	1.76	Shisa6	shisa family member 6	3112	0.34
chr4_42951254_42951979	1.74	Dnajb5	DnaJ heat shock protein family (Hsp40) member B5	1176	0.34
chr19_14591939_14592995	1.74	Tle4	transducin-like enhancer of split 4	3072	0.36
chr11_74589375_74590721	1.73	Rap1gap2	RAP1 GTPase activating protein 2	76	0.97
chr7_12017618_12017901	1.73	Gm18854	predicted gene, 18854	7692	0.07
chr11_96279294_96280222	1.68	Hoxb8	homeobox B8	2147	0.12
chr2_74682710_74683184	1.67	Gm28309	predicted gene 28309	499	0.38
chr7_16855672_16855950	1.66	Prkd2	protein kinase D2	7102	0.09
chr9_91369028_91370469	1.62	Zic4	zinc finger protein of the cerebellum 4	250	0.86
chr17_47877478_47879368	1.62	Foxp4	forkhead box P4	530	0.7
chr13_40287233_40288041	1.60	Ofcc1	orofacial cleft 1 candidate 1	374	0.92
chr1_128303840_128304009	1.59	Lct	lactase	11660	0.16
chr1_135579927_135581701	1.57	Gm4793	predicted gene 4793	3959	0.2
chr2_109693096_109694906	1.56	Bdnf	brain derived neurotrophic factor	408	0.85
chr7_49911362_49912424	1.55	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	193	0.96
chr2_35662845_35663372	1.54	Dab2ip	disabled 2 interacting protein	1489	0.47
chr5_47984794_47986445	1.52	Slit2	slit guidance ligand 2	625	0.68
chr9_45430098_45431532	1.51	4833428L15Rik	RIKEN cDNA 4833428L15 gene	417	0.52
chr5_122048053_122048751	1.50	Gm15637	predicted gene 15637	20	0.9
chr15_76007638_76007789	1.50	Fam83h	family with sequence similarity 83, member H	1785	0.15
chr6_114132286_114132783	1.49	Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	1115	0.52
chr2_158610228_158611991	1.46	Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	342	0.44
chr1_62704948_62705819	1.44	Nrp2	neuropilin 2	1681	0.35
chr8_84944349_84946109	1.44	Rtbdn	retbindin	1762	0.13
chr11_106019908_106020882	1.41	Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	6622	0.1
chr18_3120324_3120523	1.39	Vmn1r238	vomeronasal 1 receptor, 238	2989	0.21
chr5_22746211_22746970	1.39	A930003O13Rik	RIKEN cDNA A930003O13 gene	297	0.65
chr18_20616572_20616723	1.38	Gm16090	predicted gene 16090	48613	0.1
chr8_121118797_121121438	1.35	Foxc2	forkhead box C2	3946	0.14
chrX_58028680_58029480	1.35	Zic3	zinc finger protein of the cerebellum 3	1563	0.48
chr13_94876260_94878233	1.34	Otp	orthopedia homeobox	1644	0.4
chr16_59409330_59409716	1.33	Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	2191	0.25
chr4_3179243_3179395	1.32	Vmn1r3	vomeronasal 1 receptor 3	6039	0.18
chr7_62420525_62420893	1.30	Mkrn3	makorin, ring finger protein, 3	570	0.69
chr11_78379058_78379209	1.30	Foxn1	forkhead box N1	7425	0.1
chr8_119991948_119993164	1.27	Crispld2	cysteine-rich secretory protein LCCL domain containing 2	48	0.97
chr7_12014066_12014217	1.27	Vmn1r-ps60	vomeronasal 1 receptor, pseudogene 60	9075	0.06
chr1_34536184_34537716	1.26	Cfc1	cripto, FRL-1, cryptic family 1	1302	0.22
chr13_71958597_71960663	1.23	Irx1	Iroquois homeobox 1	197	0.95
chr1_50928853_50929386	1.23	Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	1600	0.44
chr8_17533479_17533688	1.22	Csmd1	CUB and Sushi multiple domains 1	1698	0.56
chr6_55678280_55679200	1.22	Neurod6	neurogenic differentiation 6	2523	0.32
chr8_36110499_36110743	1.20	Prag1	PEAK1 related kinase activating pseudokinase 1	15760	0.17
chr11_21995570_21998947	1.18	Otx1	orthodenticle homeobox 1	4357	0.28
chr2_33639069_33641423	1.17	Lmx1b	LIM homeobox transcription factor 1 beta	234	0.85
chr6_3141742_3141936	1.16	Vmn1r261	vomeronasal 1 receptor 261	2715	0.22
chr19_12491052_12491203	1.16	Dtx4	deltex 4, E3 ubiquitin ligase	10327	0.1
chr4_120746715_120747787	1.14	Kcnq4	potassium voltage-gated channel, subfamily Q, member 4	3	0.96
chr6_52215744_52216574	1.14	Hoxa7	homeobox A7	1293	0.15
chr1_63273297_63274259	1.14	Gm24513	predicted gene, 24513	415	0.41
chr9_122595045_122595971	1.13	9530059O14Rik	RIKEN cDNA 9530059O14 gene	23006	0.13
chr1_34582116_34582629	1.13	1700101I19Rik	RIKEN cDNA 1700101I19 gene	2661	0.13
chr13_55483242_55484428	1.12	Dbn1	drebrin 1	134	0.9
chrX_36195589_36196935	1.12	Zcchc12	zinc finger, CCHC domain containing 12	276	0.9
chr2_31340092_31340284	1.11	Hmcn2	hemicentin 2	25773	0.19
chr14_122474810_122475253	1.11	2610035F20Rik	RIKEN cDNA 2610035F20 gene	168	0.73
chr2_57111288_57112991	1.11	Nr4a2	nuclear receptor subfamily 4, group A, member 2	933	0.6
chr13_36729599_36730738	1.11	Nrn1	neuritin 1	500	0.75
chr17_70521708_70522843	1.10	Dlgap1	DLG associated protein 1	113	0.98
chr4_45825879_45827166	1.09	Igfbpl1	insulin-like growth factor binding protein-like 1	401	0.81
chr14_64586889_64588168	1.09	Mir124a-1hg	Mir124-1 host gene (non-protein coding)	197	0.92
chr18_20628118_20628269	1.08	Gm16090	predicted gene 16090	37067	0.12
chr10_34299043_34301066	1.08	Tspyl4	TSPY-like 4	798	0.4
chr8_123961603_123961778	1.08	Gm45890	predicted gene 45890	9167	0.1
chr8_62953964_62954144	1.06	Spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3	2129	0.35
chr2_84882407_84884134	1.06	Rtn4rl2	reticulon 4 receptor-like 2	3206	0.17
chr9_8900980_8902109	1.05	Pgr	progesterone receptor	1076	0.65
chr6_52245764_52247193	1.05	Hoxa11os	homeobox A11, opposite strand	257	0.65
chr6_114130915_114132167	1.05	Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	122	0.97
chr1_87153907_87155134	1.03	Ecel1	endothelin converting enzyme-like 1	507	0.63
chr12_44331532_44331907	1.02	Nrcam	neuronal cell adhesion molecule	2469	0.27
chr5_113492294_113493538	1.01	Wscd2	WSC domain containing 2	2164	0.36
chr12_56669617_56669768	1.01	Gm18339	predicted gene, 18339	2721	0.2
chr10_77677226_77678457	1.01	Gm48160	predicted gene, 48160	3246	0.08
chr5_144545163_144547007	1.00	Nptx2	neuronal pentraxin 2	183	0.96
chr11_107793364_107794626	1.00	Gm11650	predicted gene 11650	129	0.87
chr6_3138626_3138777	1.00	Vmn1r261	vomeronasal 1 receptor 261	5853	0.16
chr7_135410284_135411329	1.00	Foxi2	forkhead box I2	439	0.84
chr7_16946370_16947636	0.99	Pnmal2	PNMA-like 2	2321	0.14
chr15_102199240_102199509	0.99	Zfp740	zinc finger protein 740	3875	0.12
chr10_81020701_81020852	0.98	Gm16099	predicted gene 16099	4035	0.1
chr16_38047786_38048466	0.98	Gsk3b	glycogen synthase kinase 3 beta	40875	0.15
chr10_81481482_81482676	0.98	Celf5	CUGBP, Elav-like family member 5	593	0.47
chr10_84632245_84632396	0.98	Polr3b	polymerase (RNA) III (DNA directed) polypeptide B	5814	0.16
chr11_98327227_98329144	0.97	Neurod2	neurogenic differentiation 2	1463	0.23
chr10_107271797_107272933	0.97	Lin7a	lin-7 homolog A (C. elegans)	29	0.98
chr17_45546681_45547495	0.97	Tmem151b	transmembrane protein 151B	2589	0.14
chr16_21209865_21210937	0.97	Ephb3	Eph receptor B3	123	0.96
chr11_60140654_60141006	0.96	Rai1	retinoic acid induced 1	571	0.7
chr5_116571356_116571960	0.96	Gm42854	predicted gene 42854	1837	0.33
chr12_29536509_29537451	0.95	Myt1l	myelin transcription factor 1-like	1758	0.36
chr6_112945034_112945954	0.94	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	1260	0.31
chr13_70840476_70842094	0.94	Adamts16	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16	490	0.63
chr3_88206822_88208169	0.93	Gm3764	predicted gene 3764	183	0.86
chr4_3176853_3177004	0.93	Vmn1r2	vomeronasal 1 receptor 2	4845	0.19
chr19_60146143_60147364	0.92	E330013P04Rik	RIKEN cDNA E330013P04 gene	2049	0.34
chr14_14345697_14346878	0.92	Il3ra	interleukin 3 receptor, alpha chain	12	0.94
chr1_172019783_172020083	0.91	Vangl2	VANGL planar cell polarity 2	6778	0.14
chr10_32889495_32890861	0.90	Nkain2	Na+/K+ transporting ATPase interacting 2	283	0.94
chr7_140921494_140921663	0.90	Nlrp6	NLR family, pyrin domain containing 6	507	0.53
chr8_117261523_117261917	0.90	Cmip	c-Maf inducing protein	4603	0.29
chr2_79047843_79048374	0.89	Gm14469	predicted gene 14469	9374	0.22
chr18_23038815_23040349	0.89	Nol4	nucleolar protein 4	496	0.88
chr6_93911298_93911653	0.88	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	1029	0.62
chr3_107516925_107518261	0.88	Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	156	0.95
chr2_168741115_168741891	0.88	Atp9a	ATPase, class II, type 9A	297	0.9
chr4_152315082_152316464	0.88	Rnf207	ring finger protein 207	192	0.9
chr17_43157421_43159105	0.87	E130008D07Rik	RIKEN cDNA E130008D07 gene	3	0.99
chr13_53468029_53468614	0.86	Msx2	msh homeobox 2	4753	0.22
chr7_137320313_137320714	0.86	Ebf3	early B cell factor 3	6068	0.2
chr2_146834060_146838027	0.86	Gm14114	predicted gene 14114	3689	0.27
chr7_46396141_46398423	0.86	Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	366	0.84
chr15_74516560_74519631	0.85	Adgrb1	adhesion G protein-coupled receptor B1	1264	0.47
chr11_78324277_78325061	0.85	Aldoc	aldolase C, fructose-bisphosphate	343	0.73
chr3_116251586_116252641	0.84	Gpr88	G-protein coupled receptor 88	976	0.56
chr19_26977814_26977965	0.84	Gm50121	predicted gene, 50121	48092	0.16
chr8_121648291_121648878	0.84	Zcchc14	zinc finger, CCHC domain containing 14	4317	0.14
chr6_52167312_52169129	0.84	Hoxaas2	Hoxa cluster antisense RNA 2	290	0.7
chr18_20620618_20620769	0.84	Gm16090	predicted gene 16090	44567	0.11
chr9_63139436_63140636	0.83	Gm25064	predicted gene, 25064	6753	0.18
chr11_44626786_44627224	0.83	Ebf1	early B cell factor 1	5244	0.18
chr2_59562878_59563170	0.82	Gm13552	predicted gene 13552	1660	0.44
chr7_112954380_112955414	0.82	Rassf10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10	935	0.58
chr1_138837882_138838896	0.82	Lhx9	LIM homeobox protein 9	4040	0.18
chr6_42323611_42324574	0.82	Fam131b	family with sequence similarity 131, member B	500	0.63
chr1_9298603_9300104	0.82	Sntg1	syntrophin, gamma 1	71	0.97
chr13_49052160_49052311	0.82	Wnk2	WNK lysine deficient protein kinase 2	8648	0.25
chr3_88192448_88192599	0.81	AW047730	expressed sequence AW047730	8100	0.08
chr4_107806247_107806480	0.81	Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	3495	0.13
chr16_38902338_38903630	0.81	Igsf11	immunoglobulin superfamily, member 11	476	0.81
chr1_131523488_131524457	0.81	Srgap2	SLIT-ROBO Rho GTPase activating protein 2	3375	0.18
chr4_110282527_110283235	0.80	Elavl4	ELAV like RNA binding protein 4	3735	0.36
chr9_41581166_41581549	0.80	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	4	0.85
chr12_95691954_95693678	0.79	Flrt2	fibronectin leucine rich transmembrane protein 2	590	0.73
chr2_24468213_24468491	0.79	Pax8	paired box 8	6745	0.14
chr19_5684246_5684716	0.79	Pcnx3	pecanex homolog 3	188	0.83
chr11_96354030_96355123	0.79	Hoxb3os	homeobox B3 and homeobox B2, opposite strand	115	0.91
chr4_143349521_143350697	0.79	Lrrc38	leucine rich repeat containing 38	352	0.83
chrX_60892404_60893251	0.78	Sox3	SRY (sex determining region Y)-box 3	603	0.52
chr2_28514501_28514925	0.78	Ralgds	ral guanine nucleotide dissociation stimulator	1387	0.27
chr10_128644549_128644700	0.78	Ikzf4	IKAROS family zinc finger 4	24	0.92
chr10_96460605_96460885	0.78	Gm8601	predicted gene 8601	15734	0.19
chr10_86491670_86492273	0.78	Syn3	synapsin III	74	0.96
chrX_101302912_101303071	0.77	Nlgn3	neuroligin 3	2517	0.16
chr10_118758948_118759153	0.77	Gm47425	predicted gene, 47425	39622	0.12
chr11_80481116_80481835	0.76	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	4419	0.21
chr2_109677166_109678631	0.76	Bdnf	brain derived neurotrophic factor	866	0.48
chr7_57509014_57510202	0.76	Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	237	0.95
chr8_93812106_93812875	0.76	Gnao1	guanine nucleotide binding protein, alpha O	1177	0.35
chr17_93198991_93201483	0.75	Adcyap1	adenylate cyclase activating polypeptide 1	302	0.89
chr10_82223005_82223164	0.75	Zfp938	zinc finger protein 938	18189	0.13
chr15_102997539_102998176	0.74	Hoxc6	homeobox C6	400	0.68
chr14_52313293_52314443	0.74	Sall2	spalt like transcription factor 2	2455	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.5	0.5	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.4	1.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.4	1.7	GO:0007412	axon target recognition(GO:0007412)
0.4	1.1	GO:0021586	pons maturation(GO:0021586)
0.4	1.1	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	1.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.3	0.9	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.3	1.5	GO:0036233	glycine import(GO:0036233)
0.3	1.5	GO:0015816	glycine transport(GO:0015816)
0.3	1.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	0.9	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.3	1.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.3	0.8	GO:0045218	zonula adherens maintenance(GO:0045218)
0.3	0.8	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.3	0.8	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2	0.7	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2	1.2	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2	1.0	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.2	0.7	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.2	0.7	GO:0015888	thiamine transport(GO:0015888)
0.2	0.9	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2	0.9	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	0.8	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.2	0.6	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.2	0.4	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2	1.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	0.6	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	0.8	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2	0.4	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.2	0.5	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2	0.5	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.2	0.5	GO:0001661	conditioned taste aversion(GO:0001661)
0.2	0.6	GO:0046959	habituation(GO:0046959)
0.2	0.8	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2	0.8	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.2	0.8	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.2	0.5	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2	0.8	GO:0070842	aggresome assembly(GO:0070842)
0.2	0.5	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.2	0.6	GO:0030035	microspike assembly(GO:0030035)
0.2	0.9	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.4	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.4	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.4	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.8	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.4	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	1.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.4	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.5	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	0.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.5	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.1	0.4	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.1	0.4	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.2	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.5	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.2	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.1	0.3	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	0.3	GO:0032439	endosome localization(GO:0032439)
0.1	0.3	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.4	GO:1902534	single-organism membrane invagination(GO:1902534)
0.1	0.2	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.1	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	0.5	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.3	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	0.2	GO:0072069	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.1	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.6	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	1.0	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.1	0.2	GO:0051795	positive regulation of catagen(GO:0051795)
0.1	0.2	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.1	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.1	0.5	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.5	GO:0072044	collecting duct development(GO:0072044)
0.1	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.1	1.6	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.1	0.5	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1	0.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.2	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1	0.3	GO:0009414	response to water deprivation(GO:0009414)
0.1	0.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.7	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	0.2	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	0.2	GO:0072143	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	0.2	GO:0021557	oculomotor nerve development(GO:0021557) trochlear nerve development(GO:0021558)
0.1	0.4	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.2	GO:0072318	clathrin coat disassembly(GO:0072318)
0.1	0.2	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	1.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.1	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	0.2	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.1	0.3	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.4	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.2	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1	0.3	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.2	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1	0.4	GO:0021854	hypothalamus development(GO:0021854)
0.1	0.1	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698)
0.1	0.2	GO:0036166	phenotypic switching(GO:0036166)
0.1	0.3	GO:0010288	response to lead ion(GO:0010288)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1	0.6	GO:0051764	actin crosslink formation(GO:0051764)
0.1	1.0	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1	1.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.8	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.1	0.1	GO:0060847	endothelial cell fate specification(GO:0060847)
0.1	0.5	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.3	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.3	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.3	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.1	0.5	GO:0021860	pyramidal neuron development(GO:0021860)
0.1	0.1	GO:0048880	sensory system development(GO:0048880)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.5	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.4	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1	0.2	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:0051593	response to folic acid(GO:0051593)
0.1	0.2	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.2	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.1	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.3	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.1	0.2	GO:0060460	left lung morphogenesis(GO:0060460)
0.1	0.1	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.1	0.2	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.1	0.2	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.1	0.8	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1	0.2	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1	0.4	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.2	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.5	GO:0070255	regulation of mucus secretion(GO:0070255)
0.0	0.0	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.9	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.1	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.6	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0060601	lateral sprouting from an epithelium(GO:0060601)
0.0	0.2	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.0	0.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.3	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.0	0.2	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	3.8	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.2	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.5	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.0	0.9	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.4	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.3	GO:0043586	tongue development(GO:0043586)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.0	0.1	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.2	GO:0060346	bone trabecula formation(GO:0060346)
0.0	0.3	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.6	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.3	GO:0042640	anagen(GO:0042640)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.0	1.2	GO:0045687	positive regulation of glial cell differentiation(GO:0045687)
0.0	0.1	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.4	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.4	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.2	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.3	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.2	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.7	GO:0001964	startle response(GO:0001964)
0.0	0.2	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.4	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.6	GO:0003016	respiratory system process(GO:0003016)
0.0	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.4	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0098597	vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.8	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.2	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.1	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.2	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.1	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.9	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.1	GO:0086064	cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.2	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.0	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.0	GO:0033239	negative regulation of cellular amine metabolic process(GO:0033239)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199) chemorepulsion of axon(GO:0061643)
0.0	0.0	GO:0061526	acetylcholine secretion(GO:0061526)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.6	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.3	GO:1902307	positive regulation of sodium ion transmembrane transport(GO:1902307)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.0	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.0	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.0	GO:2000449	regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.2	GO:0036065	fucosylation(GO:0036065)
0.0	0.2	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.0	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.0	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.0	0.0	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.3	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.8	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.4	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	0.2	GO:0003352	regulation of cilium movement(GO:0003352)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.5	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	1.9	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0060379	cardiac muscle cell myoblast differentiation(GO:0060379)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.0	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.2	GO:0090103	cochlea morphogenesis(GO:0090103)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0048339	paraxial mesoderm development(GO:0048339)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0061430	bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0006582	melanin metabolic process(GO:0006582)
0.0	0.2	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.0	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.0	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.3	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.8	GO:0008306	associative learning(GO:0008306)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.0	GO:0050975	sensory perception of touch(GO:0050975)
0.0	0.1	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:2000727	positive regulation of cardiac muscle cell differentiation(GO:2000727)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.0	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.0	0.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.2	GO:0009452	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process through glucose-1-phosphate(GO:0061622) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:1904659	glucose transmembrane transport(GO:1904659)
0.0	0.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.0	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	1.7	GO:0045665	negative regulation of neuron differentiation(GO:0045665)
0.0	1.2	GO:0098792	xenophagy(GO:0098792)
0.0	0.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.0	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.0	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:0090656	t-circle formation(GO:0090656)
0.0	0.0	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.0	GO:1903059	regulation of protein lipidation(GO:1903059)
0.0	0.1	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.0	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0048665	neuron fate specification(GO:0048665)
0.0	0.1	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.0	0.0	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.0	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.0	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.0	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.0	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.0	0.0	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.0	0.0	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0043307	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.0	GO:0002254	kinin cascade(GO:0002254)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.0	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.0	0.1	GO:0032196	transposition(GO:0032196)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.2	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.0	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.0	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0003190	atrioventricular valve formation(GO:0003190)
0.0	0.2	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.0	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.0	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.0	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.0	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.1	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.0	0.2	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0018214	protein carboxylation(GO:0018214)
0.0	0.7	GO:0007269	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0	0.0	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3	1.3	GO:0044308	axonal spine(GO:0044308)
0.2	1.0	GO:0044316	cone cell pedicle(GO:0044316)
0.2	0.5	GO:0097454	Schwann cell microvillus(GO:0097454)
0.2	0.7	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.2	0.7	GO:0044393	microspike(GO:0044393)
0.2	0.3	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2	1.8	GO:0030061	mitochondrial crista(GO:0030061)
0.2	0.5	GO:0005914	spot adherens junction(GO:0005914)
0.1	0.6	GO:0033269	internode region of axon(GO:0033269)
0.1	0.8	GO:0005915	zonula adherens(GO:0005915)
0.1	0.6	GO:0005638	lamin filament(GO:0005638)
0.1	0.5	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.5	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	1.4	GO:0032279	asymmetric synapse(GO:0032279)
0.1	0.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	2.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.8	GO:0043194	axon initial segment(GO:0043194)
0.1	2.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	0.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.3	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	1.3	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.3	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	1.3	GO:0030057	desmosome(GO:0030057)
0.1	0.2	GO:0070552	BRISC complex(GO:0070552)
0.1	0.2	GO:0055087	Ski complex(GO:0055087)
0.1	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.1	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.5	GO:0032433	filopodium tip(GO:0032433)
0.0	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.6	GO:0033391	chromatoid body(GO:0033391)
0.0	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.4	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.2	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.3	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.4	GO:0061702	inflammasome complex(GO:0061702)
0.0	1.3	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	4.8	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.0	5.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	1.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.0	GO:0072534	perineuronal net(GO:0072534)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	1.1	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	2.2	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.4	GO:0008305	integrin complex(GO:0008305)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	4.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.6	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	1.4	GO:0043679	axon terminus(GO:0043679)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.0	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.5	GO:0005776	autophagosome(GO:0005776)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.3	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4	1.5	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.3	1.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.3	1.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	0.9	GO:0097016	L27 domain binding(GO:0097016)
0.3	1.7	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.7	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2	0.9	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	1.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	1.6	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.2	0.8	GO:0005042	netrin receptor activity(GO:0005042)
0.2	1.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.1	1.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.6	GO:0035326	enhancer binding(GO:0035326)
0.1	0.7	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.9	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.5	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	0.6	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.8	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.5	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	1.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	0.8	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.7	GO:0018650	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	0.8	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.1	1.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.5	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	0.9	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	1.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0038100	nodal binding(GO:0038100)
0.1	0.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	1.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	1.1	GO:0032183	SUMO binding(GO:0032183)
0.1	0.7	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.8	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.7	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	1.0	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.3	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.1	0.2	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.1	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	0.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.7	GO:0031005	filamin binding(GO:0031005)
0.1	0.6	GO:0046977	TAP binding(GO:0046977)
0.1	0.4	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.2	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	1.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.6	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.5	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.2	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0002134	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.4	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.3	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	1.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.5	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.3	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.7	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.4	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.2	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.2	GO:0034951	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.5	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	1.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.0	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.4	GO:0043236	laminin binding(GO:0043236)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	1.2	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.4	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	1.7	GO:0005550	pheromone binding(GO:0005550)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.4	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	15.4	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	1.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.0	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	1.0	GO:0019838	growth factor binding(GO:0019838)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0018575	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.0	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	0.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	1.8	PID REELIN PATHWAY	Reelin signaling pathway
0.1	1.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	2.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	1.1	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	3.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	3.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.4	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	2.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	1.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.0	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	1.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.0	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions

Results for Tfap2b

Z-value: 1.40

Motif logo

Transcription factors associated with Tfap2b

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tfap2b motif across conditions

Conditions sorted by the z-value of the Tfap2b motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: