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ENCODE: H3K4me3 ChIP-Seq of different mouse tissues during embryonic development
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Results for Zbtb49

Z-value: 0.67

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Transcription factors associated with Zbtb49

Gene Symbol Gene ID Gene Info
Zbtb49
ENSMUSG00000029127.9 zinc finger and BTB domain containing 49

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_38219951_38220398Zbtb492390.5513650.094.8e-01Click!
chr5_38218735_38218938Zbtb4915770.269187-0.047.7e-01Click!

Activity of the Zbtb49 motif across conditions

Conditions sorted by the z-value of the Zbtb49 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_115908055_115909691 2.28 Cit
 citron
 1403
 0.37
chr12_61525659_61526870 2.11 Lrfn5
 leucine rich repeat and fibronectin type III domain containing 5
 2316
 0.3
chr9_96728847_96729194 2.06 Zbtb38
 zinc finger and BTB domain containing 38
 16
 0.97
chr3_4798346_4798833 1.82 1110015O18Rik
 RIKEN cDNA 1110015O18 gene
 119
 0.97
chr8_84769068_84769679 1.69 Nfix
 nuclear factor I/X
 4023
 0.13
chr7_140154045_140155011 1.56 Sprn
 shadow of prion protein
 349
 0.75
chr2_181155937_181157234 1.51 Eef1a2
 eukaryotic translation elongation factor 1 alpha 2
 429
 0.73
chr9_40268795_40270233 1.32 Scn3b
 sodium channel, voltage-gated, type III, beta
 81
 0.96
chr7_126822762_126823312 1.28 Fam57b
 family with sequence similarity 57, member B
 266
 0.74
chr5_5264770_5266186 1.18 Cdk14
 cyclin-dependent kinase 14
 169
 0.96
chr2_92399780_92399931 1.16 Mapk8ip1
 mitogen-activated protein kinase 8 interacting protein 1
 1408
 0.25
chr13_8207058_8207829 1.14 Adarb2
 adenosine deaminase, RNA-specific, B2
 4521
 0.2
chr4_24429901_24430719 1.13 Gm27243
 predicted gene 27243
 580
 0.79
chrX_103184741_103184892 1.08 Nap1l2
 nucleosome assembly protein 1-like 2
 1824
 0.25
chr16_43510268_43510725 1.06 Zbtb20
 zinc finger and BTB domain containing 20
 188
 0.96
chr1_32172319_32173236 1.04 Khdrbs2
 KH domain containing, RNA binding, signal transduction associated 2
 29
 0.99
chr1_164454554_164455430 0.99 Atp1b1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 1215
 0.39
chr7_139833633_139836105 0.99 Adgra1
 adhesion G protein-coupled receptor A1
 93
 0.96
chr10_127165174_127166341 0.92 B4galnt1
 beta-1,4-N-acetyl-galactosaminyl transferase 1
 74
 0.93
chr9_113792658_113793898 0.91 Clasp2
 CLIP associating protein 2
 48
 0.98
chr19_39812576_39812727 0.87 Cyp2c40
 cytochrome P450, family 2, subfamily c, polypeptide 40
 93
 0.98
chr15_76519928_76521866 0.87 Scrt1
 scratch family zinc finger 1
 1005
 0.28
chr1_83407298_83408547 0.87 Sphkap
 SPHK1 interactor, AKAP domain containing
 217
 0.94
chr18_61910602_61911795 0.84 Ablim3
 actin binding LIM protein family, member 3
 625
 0.73
chr1_132199896_132201879 0.82 Lemd1
 LEM domain containing 1
 76
 0.95
chr8_95703051_95704038 0.80 Ndrg4
 N-myc downstream regulated gene 4
 474
 0.68
chr13_69736281_69736725 0.80 Ube2ql1
 ubiquitin-conjugating enzyme E2Q family-like 1
 3386
 0.16
chr5_120428678_120429275 0.80 Lhx5
 LIM homeobox protein 5
 2723
 0.18
chr4_122955098_122956090 0.80 Mfsd2a
 major facilitator superfamily domain containing 2A
 4396
 0.16
chr18_25747291_25747951 0.78 Celf4
 CUGBP, Elav-like family member 4
 5071
 0.25
chr12_36153893_36154044 0.76 Bzw2
 basic leucine zipper and W2 domains 2
 2659
 0.17
chr5_112576144_112577196 0.76 Sez6l
 seizure related 6 homolog like
 198
 0.92
chr8_4492894_4494304 0.75 Cers4
 ceramide synthase 4
 23
 0.97
chr10_104819342_104819493 0.75 Gm25522
 predicted gene, 25522
 45891
 0.17
chr5_70379643_70379794 0.68 Gm26072
 predicted gene, 26072
 171229
 0.03
chr9_21037316_21038046 0.68 Gm26592
 predicted gene, 26592
 101
 0.9
chr8_120492701_120493230 0.68 Gse1
 genetic suppressor element 1, coiled-coil protein
 4518
 0.17
chr5_27261637_27262396 0.67 Dpp6
 dipeptidylpeptidase 6
 41
 0.98
chrX_136666183_136667703 0.66 Tceal3
 transcription elongation factor A (SII)-like 3
 332
 0.84
chr12_80769848_80770025 0.65 Ccdc177
 coiled-coil domain containing 177
 9249
 0.12
chr17_24643558_24645911 0.65 Slc9a3r2
 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
 223
 0.82
chr5_137553079_137554278 0.65 Actl6b
 actin-like 6B
 121
 0.89
chr5_24607000_24607197 0.64 Smarcd3
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
 5086
 0.11
chr15_76721855_76722516 0.63 Lrrc24
 leucine rich repeat containing 24
 12
 0.92
chr15_74565280_74565930 0.61 Adgrb1
 adhesion G protein-coupled receptor B1
 1704
 0.27
chr11_96305580_96306179 0.61 Hoxb5os
 homeobox B5 and homeobox B6, opposite strand
 798
 0.33
chr7_25607189_25607340 0.60 Gm4607
 predicted gene 4607
 5938
 0.09
chr2_106699616_106699779 0.60 Mpped2
 metallophosphoesterase domain containing 2
 3843
 0.29
chr2_115898028_115898179 0.59 Meis2
 Meis homeobox 2
 25141
 0.25
chr4_127015642_127016128 0.59 Sfpq
 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
 5439
 0.13
chr11_73281234_73281630 0.58 Trpv3
 transient receptor potential cation channel, subfamily V, member 3
 14044
 0.1
chr10_18470218_18471289 0.57 Nhsl1
 NHS-like 1
 772
 0.72
chr3_60489739_60489921 0.57 Mbnl1
 muscleblind like splicing factor 1
 11105
 0.24
chr18_64340633_64341751 0.56 Onecut2
 one cut domain, family member 2
 1172
 0.45
chr1_119525279_119525430 0.56 Tmem185b
 transmembrane protein 185B
 806
 0.38
chr11_109653199_109653966 0.56 Prkar1a
 protein kinase, cAMP dependent regulatory, type I, alpha
 2661
 0.23
chr1_109982396_109983459 0.55 Cdh7
 cadherin 7, type 2
 54
 0.99
chr15_103011882_103012844 0.55 Hoxc5
 homeobox C5
 1452
 0.19
chr14_96517868_96518996 0.55 Klhl1
 kelch-like 1
 670
 0.78
chr1_87184698_87185439 0.55 Prss56
 protease, serine 56
 1755
 0.2
chr5_115475784_115476389 0.54 Sirt4
 sirtuin 4
 3852
 0.1
chr4_119539113_119539523 0.53 Frg2f1
 FSHD region gene 2 family member 1
 188
 0.65
chr6_137252157_137253458 0.52 Ptpro
 protein tyrosine phosphatase, receptor type, O
 342
 0.92
chr15_34495344_34495864 0.51 Pop1
 processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
 281
 0.54
chr6_28924063_28924220 0.51 Snd1
 staphylococcal nuclease and tudor domain containing 1
 44098
 0.13
chr19_5691875_5693863 0.51 Map3k11
 mitogen-activated protein kinase kinase kinase 11
 26
 0.92
chr9_54286058_54287026 0.50 Gldn
 gliomedin
 56
 0.97
chr2_30358021_30359257 0.50 Sh3glb2
 SH3-domain GRB2-like endophilin B2
 601
 0.55
chr10_107890113_107890543 0.50 Otogl
 otogelin-like
 21806
 0.24
chr9_50856443_50856925 0.49 Ppp2r1b
 protein phosphatase 2, regulatory subunit A, beta
 240
 0.91
chr11_76396066_76396459 0.48 Nxn
 nucleoredoxin
 2806
 0.25
chr18_69384485_69384729 0.47 Tcf4
 transcription factor 4
 31290
 0.22
chr5_81021302_81022876 0.47 Adgrl3
 adhesion G protein-coupled receptor L3
 279
 0.95
chr11_105364219_105365174 0.46 Gm11638
 predicted gene 11638
 1444
 0.39
chr9_45432313_45432910 0.46 4833428L15Rik
 RIKEN cDNA 4833428L15 gene
 881
 0.47
chr4_148130089_148131325 0.46 Draxin
 dorsal inhibitory axon guidance protein
 9
 0.72
chr3_87959939_87961181 0.46 Gm3745
 predicted gene 3745
 7626
 0.09
chr11_23124548_23125169 0.45 1700061J23Rik
 RIKEN cDNA 1700061J23 gene
 27282
 0.14
chr4_134400063_134400411 0.45 Pafah2
 platelet-activating factor acetylhydrolase 2
 2675
 0.18
chr3_98941003_98941978 0.45 5730437C11Rik
 RIKEN cDNA 5730437C11 gene
 234
 0.92
chr17_44082773_44083036 0.45 Enpp5
 ectonucleotide pyrophosphatase/phosphodiesterase 5
 4025
 0.24
chr15_57975359_57975957 0.45 Fam83a
 family with sequence similarity 83, member A
 9761
 0.16
chr7_16131445_16132800 0.44 Slc8a2
 solute carrier family 8 (sodium/calcium exchanger), member 2
 1774
 0.23
chr9_118227365_118228117 0.44 Gm17399
 predicted gene, 17399
 77510
 0.09
chr2_154570084_154570341 0.43 E2f1
 E2F transcription factor 1
 320
 0.81
chr17_13682256_13683548 0.43 Gm16046
 predicted gene 16046
 585
 0.68
chr13_99512095_99512261 0.42 Map1b
 microtubule-associated protein 1B
 4340
 0.18
chr15_94197097_94197248 0.42 Adamts20
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
 207086
 0.02
chr4_82344703_82345124 0.42 n-R5s188
 nuclear encoded rRNA 5S 188
 94497
 0.08
chr7_141122888_141123988 0.41 Ptdss2
 phosphatidylserine synthase 2
 1056
 0.29
chr4_141052695_141054311 0.41 Crocc
 ciliary rootlet coiled-coil, rootletin
 158
 0.92
chr10_12940976_12941914 0.41 B230208H11Rik
 RIKEN cDNA B230208H11 gene
 18355
 0.17
chr2_154359544_154359723 0.41 Cdk5rap1
 CDK5 regulatory subunit associated protein 1
 5289
 0.19
chr18_47648563_47648791 0.41 Gm5236
 predicted gene 5236
 81090
 0.08
chr6_119328752_119331284 0.41 Lrtm2
 leucine-rich repeats and transmembrane domains 2
 739
 0.43
chr10_108365083_108365548 0.40 Gm23105
 predicted gene, 23105
 1650
 0.39
chr9_120305155_120305306 0.40 Myrip
 myosin VIIA and Rab interacting protein
 1294
 0.38
chr10_84060694_84061226 0.40 Gm37908
 predicted gene, 37908
 798
 0.64
chr13_102811110_102811952 0.40 Mast4
 microtubule associated serine/threonine kinase family member 4
 10610
 0.23
chr19_10041589_10042653 0.40 Fads3
 fatty acid desaturase 3
 389
 0.78
chr5_77460063_77460528 0.40 1700017L05Rik
 RIKEN cDNA 1700017L05 gene
 5193
 0.17
chr18_73863569_73864469 0.39 Mro
 maestro
 347
 0.9
chr5_125532320_125533519 0.39 Tmem132b
 transmembrane protein 132B
 532
 0.76
chr13_94025180_94025378 0.38 Cycs-ps3
 cytochrome c, pseudogene 3
 28564
 0.14
chr9_40453562_40453959 0.38 Gramd1b
 GRAM domain containing 1B
 1910
 0.3
chr4_101508533_101509308 0.38 Dnajc6
 DnaJ heat shock protein family (Hsp40) member C6
 890
 0.64
chr11_119913855_119915054 0.38 Chmp6
 charged multivesicular body protein 6
 439
 0.76
chr2_118862035_118862506 0.38 Ivd
 isovaleryl coenzyme A dehydrogenase
 242
 0.89
chr1_91398918_91399115 0.38 Ilkap
 integrin-linked kinase-associated serine/threonine phosphatase 2C
 201
 0.89
chr16_91646595_91646873 0.37 Gart
 phosphoribosylglycinamide formyltransferase
 178
 0.84
chr12_24657601_24657860 0.37 Klf11
 Kruppel-like factor 11
 5576
 0.16
chr7_42592149_42592824 0.37 Zfp977
 zinc finger protein 977
 61
 0.96
chr12_112722274_112723056 0.37 Cep170b
 centrosomal protein 170B
 471
 0.67
chr7_46099780_46100565 0.37 Kcnj11
 potassium inwardly rectifying channel, subfamily J, member 11
 65
 0.95
chr13_43284609_43284796 0.37 Gfod1
 glucose-fructose oxidoreductase domain containing 1
 18703
 0.2
chrX_8205722_8206558 0.36 Porcn
 porcupine O-acyltransferase
 351
 0.79
chr9_21130674_21131701 0.36 Tyk2
 tyrosine kinase 2
 1
 0.95
chr16_33847136_33847287 0.36 Itgb5
 integrin beta 5
 17534
 0.16
chr6_135526679_135526846 0.36 Gm25136
 predicted gene, 25136
 57430
 0.13
chr7_4993272_4994998 0.36 Zfp579
 zinc finger protein 579
 1205
 0.21
chr5_3151730_3152673 0.35 Gm8715
 predicted gene 8715
 28424
 0.13
chr5_143009425_143009646 0.35 Rnf216
 ring finger protein 216
 7239
 0.16
chr14_64126114_64126329 0.35 9630015K15Rik
 RIKEN cDNA 9630015K15 gene
 9907
 0.13
chr17_74316487_74316684 0.35 Dpy30
 dpy-30, histone methyltransferase complex regulatory subunit
 122
 0.94
chr1_38835637_38836715 0.34 Lonrf2
 LON peptidase N-terminal domain and ring finger 2
 198
 0.94
chr17_6489757_6490685 0.34 Tmem181b-ps
 transmembrane protein 181B, pseudogene
 23199
 0.14
chr9_98428203_98428354 0.34 Rbp1
 retinol binding protein 1, cellular
 5317
 0.23
chr15_63780688_63780839 0.34 Gm46499
 predicted gene, 46499
 20602
 0.1
chr7_142757390_142757797 0.33 Gm7290
 predicted pseudogene 7290
 259
 0.9
chr7_70929709_70930345 0.33 Gm34783
 predicted gene, 34783
 17207
 0.23
chr2_137163627_137163778 0.33 Gm28214
 predicted gene 28214
 35281
 0.19
chr14_34569383_34570378 0.33 Ldb3
 LIM domain binding 3
 7114
 0.13
chr13_94680868_94681019 0.33 Gm32305
 predicted gene, 32305
 19413
 0.14
chrX_9199674_9200884 0.33 Lancl3
 LanC lantibiotic synthetase component C-like 3 (bacterial)
 377
 0.83
chr5_35448122_35448615 0.33 Gm43377
 predicted gene 43377
 52270
 0.09
chr11_72962601_72963125 0.33 Atp2a3
 ATPase, Ca++ transporting, ubiquitous
 1573
 0.28
chr12_79191005_79191867 0.32 Rdh11
 retinol dehydrogenase 11
 357
 0.78
chrX_161719845_161720465 0.32 Rai2
 retinoic acid induced 2
 2528
 0.41
chr11_79340125_79340687 0.32 Nf1
 neurofibromin 1
 519
 0.76
chr14_33444094_33444245 0.32 Mapk8
 mitogen-activated protein kinase 8
 2973
 0.2
chr7_111054563_111054714 0.31 Ctr9
 CTR9 homolog, Paf1/RNA polymerase II complex component
 848
 0.54
chr17_25809082_25810175 0.31 Fbxl16
 F-box and leucine-rich repeat protein 16
 543
 0.42
chr19_4126003_4127028 0.31 Tmem134
 transmembrane protein 134
 486
 0.4
chr17_6320795_6321910 0.31 AC183097.1
 transmembrane protein 181 (TMEM181) pseudogene
 384
 0.76
chr11_97812280_97813382 0.31 Lasp1
 LIM and SH3 protein 1
 2417
 0.14
chr17_24208374_24209710 0.31 BC028777
 cDNA sequence BC028777
 181
 0.66
chr17_6256598_6257723 0.31 Tmem181a
 transmembrane protein 181A
 210
 0.91
chr3_142559923_142560770 0.31 Gbp3
 guanylate binding protein 3
 65
 0.96
chr12_75701139_75702422 0.30 Wdr89
 WD repeat domain 89
 32243
 0.16
chr5_38598055_38598428 0.30 4930421P07Rik
 RIKEN cDNA 4930421P07 gene
 23210
 0.16
chr1_186555744_186555937 0.29 A730004F24Rik
 RIKEN cDNA A730004F24 gene
 2632
 0.36
chr3_8684903_8685755 0.29 Gm23670
 predicted gene, 23670
 5852
 0.16
chr11_116030567_116031392 0.29 Unk
 unkempt family zinc finger
 656
 0.53
chr4_28812623_28812910 0.29 Epha7
 Eph receptor A7
 365
 0.88
chr7_73654506_73654727 0.28 Gm26176
 predicted gene, 26176
 8527
 0.09
chr2_28840464_28841222 0.28 Ddx31
 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
 384
 0.54
chr16_52450441_52451342 0.28 Alcam
 activated leukocyte cell adhesion molecule
 1574
 0.55
chr17_29883165_29884481 0.28 Mdga1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 3659
 0.2
chr3_58987083_58987709 0.28 Rpl13-ps6
 ribosomal protein L13, pseudogene 6
 226
 0.9
chr7_126702563_126704731 0.28 Coro1a
 coronin, actin binding protein 1A
 473
 0.55
chr2_127070718_127071288 0.28 Blvra
 biliverdin reductase A
 310
 0.87
chr3_94954464_94954835 0.28 Rfx5
 regulatory factor X, 5 (influences HLA class II expression)
 114
 0.92
chr10_61080083_61080288 0.28 Pcbd1
 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
 9146
 0.13
chr2_70126636_70126952 0.27 Myo3b
 myosin IIIB
 30496
 0.2
chr15_102203042_102203419 0.27 Zfp740
 zinc finger protein 740
 19
 0.69
chr1_87467212_87467595 0.27 Snorc
 secondary ossification center associated regulator of chondrocyte maturation
 2868
 0.18
chr2_58565057_58565662 0.26 Acvr1
 activin A receptor, type 1
 1467
 0.38
chr6_72598511_72599213 0.26 Retsat
 retinol saturase (all trans retinol 13,14 reductase)
 234
 0.65
chr3_51234712_51234887 0.26 Gm38357
 predicted gene, 38357
 2882
 0.19
chr3_127705323_127706456 0.26 1500005C15Rik
 RIKEN cDNA 1500005C15 gene
 11138
 0.11
chr8_25976746_25977095 0.26 Hgsnat
 heparan-alpha-glucosaminide N-acetyltransferase
 167
 0.93
chr12_58212274_58214477 0.26 Sstr1
 somatostatin receptor 1
 1571
 0.52
chr12_105456394_105456761 0.26 D430019H16Rik
 RIKEN cDNA D430019H16 gene
 2721
 0.25
chr11_79590775_79591929 0.26 Rab11fip4
 RAB11 family interacting protein 4 (class II)
 140
 0.93
chr19_4282321_4283738 0.25 Ankrd13d
 ankyrin repeat domain 13 family, member D
 4
 0.94
chr5_138760327_138760734 0.25 Fam20c
 family with sequence similarity 20, member C
 5443
 0.2
chr11_72441409_72442226 0.25 Mybbp1a
 MYB binding protein (P160) 1a
 440
 0.75
chr2_25355573_25356319 0.25 Dpp7
 dipeptidylpeptidase 7
 112
 0.9
chr19_10769714_10769865 0.25 A430093F15Rik
 RIKEN cDNA A430093F15 gene
 12126
 0.12
chr3_106684672_106685318 0.25 Lrif1
 ligand dependent nuclear receptor interacting factor 1
 3
 0.98
chr7_123025258_123025409 0.25 Gm45846
 predicted gene 45846
 6041
 0.14
chr3_66292264_66292972 0.24 Veph1
 ventricular zone expressed PH domain-containing 1
 4130
 0.27
chrX_101532846_101533913 0.24 Taf1
 TATA-box binding protein associated factor 1
 620
 0.69
chr12_106080982_106081684 0.24 Gm46378
 predicted gene, 46378
 3037
 0.25
chr6_67037798_67037949 0.24 Gadd45a
 growth arrest and DNA-damage-inducible 45 alpha
 416
 0.69
chr17_24892273_24893815 0.24 Eme2
 essential meiotic structure-specific endonuclease subunit 2
 1141
 0.23
chr2_25400245_25401217 0.24 Npdc1
 neural proliferation, differentiation and control 1
 262
 0.77
chr17_79230829_79231720 0.24 Gm5230
 predicted gene 5230
 26775
 0.21
chr19_15193718_15194239 0.24 Gm5513
 predicted pseudogene 5513
 233212
 0.02
chr17_24736672_24737401 0.24 Msrb1
 methionine sulfoxide reductase B1
 354
 0.65
chr9_83834063_83834549 0.24 Ttk
 Ttk protein kinase
 383
 0.87
chr19_34192022_34193121 0.23 Stambpl1
 STAM binding protein like 1
 251
 0.92
chr9_107553913_107554411 0.23 Rassf1
 Ras association (RalGDS/AF-6) domain family member 1
 421
 0.54
chr2_118558327_118558555 0.23 Bmf
 BCL2 modifying factor
 8754
 0.16
chr10_95291310_95291461 0.23 Gm48880
 predicted gene, 48880
 23468
 0.13
chr15_77894951_77895251 0.23 Txn2
 thioredoxin 2
 20599
 0.13
chr17_86964856_86965294 0.23 Rhoq
 ras homolog family member Q
 1783
 0.25
chr4_130519685_130520343 0.23 Nkain1
 Na+/K+ transporting ATPase interacting 1
 37974
 0.17
chr6_59208973_59209748 0.23 Tigd2
 tigger transposable element derived 2
 490
 0.83
chr16_65819058_65819209 0.23 Vgll3
 vestigial like family member 3
 3504
 0.29

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 1.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.9 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0006551 leucine metabolic process(GO:0006551)
0.1 0.4 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.2 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.1 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.4 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.2 GO:2000847 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0046959 habituation(GO:0046959)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0099515 actin filament-based transport(GO:0099515)
0.1 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 1.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 0.6 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:1990035 calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.0 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.3 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.0 0.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.0 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 2.0 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.1 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0097466 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.0 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.0 0.0 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 0.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.0 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors