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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ALX1_ARX

Z-value: 0.90

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Transcription factors associated with ALX1_ARX

Gene Symbol	Gene ID	Gene Info
ALX1 Ensembl NCBI GeneCards UniProt	ENSG00000180318.3	ALX homeobox 1
ARX Ensembl NCBI GeneCards UniProt	ENSG00000004848.6	aristaless related homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_85799990_85800141	ALX1	126180	0.059739	-0.47	2.0e-01	Click!
chr12_85856935_85857086	ALX1	183125	0.031216	0.39	3.0e-01	Click!
chr12_85673428_85673579	ALX1	382	0.924685	-0.32	4.1e-01	Click!
chr12_85667489_85667640	ALX1	6321	0.326447	-0.31	4.2e-01	Click!
chr12_85667282_85667433	ALX1	6528	0.324781	-0.28	4.6e-01	Click!
chrX_25024484_25024635	ARX	9506	0.273047	-0.74	2.3e-02	Click!
chrX_25038619_25038839	ARX	4664	0.296008	0.72	3.0e-02	Click!
chrX_25023685_25023935	ARX	10255	0.271076	-0.68	4.2e-02	Click!
chrX_25041076_25041227	ARX	7086	0.271067	0.67	4.8e-02	Click!
chrX_25035659_25036118	ARX	1823	0.453673	0.64	6.6e-02	Click!

Activity of the ALX1_ARX motif across conditions

Conditions sorted by the z-value of the ALX1_ARX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_146046169_146046320	0.70	ENSG00000238713	.	24557	0.16
chr12_94166165_94166316	0.70	RP11-887P2.5		34641	0.16
chr20_35573807_35573970	0.68	SAMHD1	SAM domain and HD domain 1	6223	0.23
chr2_172067040_172067353	0.67	TLK1	tousled-like kinase 1	20628	0.24
chr10_97723999_97724150	0.67	CC2D2B	coiled-coil and C2 domain containing 2B	9712	0.17
chr17_46530677_46530986	0.63	SKAP1	src kinase associated phosphoprotein 1	23250	0.11
chr6_16437826_16437977	0.63	ENSG00000265642	.	9147	0.31
chrX_135818033_135818184	0.60	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	31394	0.15
chr10_33443500_33443690	0.60	NRP1	neuropilin 1	30988	0.18
chr20_43600993_43601244	0.59	STK4	serine/threonine kinase 4	5951	0.16
chr6_149829598_149829769	0.59	ENSG00000252244	.	8409	0.14
chr1_185646684_185647143	0.58	ENSG00000201596	.	43599	0.15
chr3_94093717_94093868	0.57	ENSG00000253062	.	276382	0.01
chr14_61872843_61873172	0.57	PRKCH	protein kinase C, eta	15595	0.24
chr11_46653734_46653885	0.54	HARBI1	harbinger transposase derived 1	14350	0.14
chr3_98291649_98291800	0.53	CPOX	coproporphyrinogen oxidase	20843	0.14
chr6_53206539_53206690	0.53	ELOVL5	ELOVL fatty acid elongase 5	6973	0.22
chr8_59977677_59977828	0.52	RP11-25K19.1		53847	0.13
chr4_78000086_78000237	0.50	CCNI	cyclin I	3003	0.3
chr3_170983485_170983636	0.50	TNIK	TRAF2 and NCK interacting kinase	40060	0.2
chr1_65475101_65475369	0.50	ENSG00000212257	.	13522	0.19
chr15_75414732_75414883	0.49	ENSG00000252722	.	800	0.61
chr7_50462451_50462702	0.49	ENSG00000200815	.	40502	0.17
chr3_53788532_53788827	0.49	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit	5572	0.22
chrX_41553097_41553277	0.49	GPR34	G protein-coupled receptor 34	4928	0.2
chr11_118573475_118573626	0.48	ENSG00000207462	.	499	0.68
chr5_72795152_72795340	0.47	BTF3	basic transcription factor 3	911	0.58
chr12_106979257_106979408	0.47	RFX4	regulatory factor X, 4 (influences HLA class II expression)	173	0.97
chr7_21482045_21482196	0.46	SP4	Sp4 transcription factor	14459	0.18
chr10_17548800_17549076	0.46	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	52609	0.13
chr14_70096957_70097157	0.45	KIAA0247	KIAA0247	18744	0.22
chr5_79519389_79519540	0.45	ENSG00000239159	.	15944	0.19
chr1_185643113_185643264	0.45	ENSG00000201596	.	39874	0.16
chrX_153389909_153390065	0.45	OPN1LW	opsin 1 (cone pigments), long-wave-sensitive	19711	0.12
chr9_33075698_33075952	0.44	SMU1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	832	0.59
chr22_31667328_31667479	0.44	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	20978	0.09
chr7_37329474_37329753	0.44	ELMO1	engulfment and cell motility 1	52754	0.14
chrX_15779492_15779655	0.44	CA5B	carbonic anhydrase VB, mitochondrial	11480	0.18
chr15_41956228_41956379	0.44	MGA	MGA, MAX dimerization protein	3693	0.22
chr3_157824510_157824697	0.43	SHOX2	short stature homeobox 2	311	0.83
chr1_66648150_66648486	0.43	PDE4B	phosphodiesterase 4B, cAMP-specific	30245	0.23
chr9_123961014_123961178	0.43	RAB14	RAB14, member RAS oncogene family	3051	0.2
chr12_94600310_94600885	0.43	RP11-74K11.2		20777	0.19
chr21_45440771_45440922	0.43	TRAPPC10	trafficking protein particle complex 10	8646	0.18
chr1_169547776_169547927	0.42	F5	coagulation factor V (proaccelerin, labile factor)	7868	0.22
chr1_114393077_114393228	0.42	AP4B1-AS1	AP4B1 antisense RNA 1	6105	0.14
chr4_148973362_148973513	0.42	RP11-76G10.1		94185	0.09
chr17_64310479_64310630	0.42	PRKCA	protein kinase C, alpha	11610	0.2
chr4_109029927_109030290	0.42	LEF1	lymphoid enhancer-binding factor 1	57349	0.12
chr1_209957444_209957681	0.42	C1orf74	chromosome 1 open reading frame 74	342	0.82
chr3_120163660_120163960	0.41	FSTL1	follistatin-like 1	6028	0.28
chr4_39035740_39035891	0.41	TMEM156	transmembrane protein 156	1273	0.48
chr3_197339250_197339401	0.41	AC024560.3		15394	0.19
chr10_60426464_60426615	0.40	BICC1	bicaudal C homolog 1 (Drosophila)	126756	0.06
chr4_96138306_96138502	0.40	BMPR1B	bone morphogenetic protein receptor, type IB	112898	0.07
chr3_18470958_18471238	0.40	SATB1	SATB homeobox 1	4237	0.24
chr10_8102007_8102158	0.40	GATA3	GATA binding protein 3	5313	0.35
chr3_187717065_187717289	0.40	LPP	LIM domain containing preferred translocation partner in lipoma	153895	0.04
chr13_28729339_28729490	0.40	PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	16244	0.18
chr1_225654690_225654867	0.40	RP11-496N12.6		1733	0.4
chr1_19933625_19933816	0.40	MINOS1-NBL1	MINOS1-NBL1 readthrough	10159	0.13
chr1_211526157_211526486	0.39	TRAF5	TNF receptor-associated factor 5	6615	0.27
chr22_45614758_45614909	0.39	KIAA0930	KIAA0930	5453	0.18
chr2_24953254_24953405	0.39	ENSG00000206732	.	54151	0.11
chr10_17274804_17274955	0.39	RP11-124N14.3		1953	0.24
chr9_96227227_96227603	0.39	FAM120AOS	family with sequence similarity 120A opposite strand	11541	0.14
chr17_28066618_28066769	0.39	RP11-82O19.1		21428	0.14
chr2_225897343_225897494	0.38	DOCK10	dedicator of cytokinesis 10	9741	0.26
chr13_41339497_41339648	0.38	MRPS31	mitochondrial ribosomal protein S31	5737	0.19
chr12_92691247_92691679	0.38	RP11-693J15.4		123844	0.05
chr15_45029426_45029577	0.38	TRIM69	tripartite motif containing 69	737	0.62
chr12_52645458_52645609	0.38	KRT86	keratin 86	2449	0.15
chr1_25969522_25969744	0.38	RP1-187B23.1		15969	0.18
chr2_203395606_203395757	0.38	FAM117B	family with sequence similarity 117, member B	104220	0.06
chr6_35638568_35638782	0.38	ENSG00000265527	.	6109	0.15
chrX_1699864_1700015	0.37	AKAP17A	A kinase (PRKA) anchor protein 17A	10547	0.21
chrX_41117068_41117219	0.37	RP5-1172N10.4		24257	0.17
chr6_144713753_144713904	0.37	UTRN	utrophin	48591	0.17
chr16_53578586_53578737	0.37	AKTIP	AKT interacting protein	40338	0.16
chrY_1649865_1650016	0.37	NA	NA	> 10⁶	NA
chr13_47243748_47243899	0.37	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	10148	0.29
chr6_2893026_2893177	0.37	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	10413	0.18
chr9_123694906_123695182	0.37	TRAF1	TNF receptor-associated factor 1	3593	0.27
chr1_100863756_100864116	0.37	ENSG00000216067	.	19605	0.19
chr20_32828478_32828629	0.37	ASIP	agouti signaling protein	19618	0.16
chr4_183839462_183839895	0.36	DCTD	dCMP deaminase	589	0.83
chr5_130730727_130730878	0.36	CDC42SE2	CDC42 small effector 2	9503	0.3
chr6_143189800_143189951	0.36	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	31691	0.22
chr3_15380688_15380839	0.36	ENSG00000201162	.	493	0.72
chr10_111776073_111776241	0.36	ADD3	adducin 3 (gamma)	8435	0.21
chr2_231517982_231518133	0.36	CAB39	calcium binding protein 39	59503	0.11
chr2_205812915_205813103	0.36	PARD3B	par-3 family cell polarity regulator beta	402286	0.01
chr4_42685625_42685776	0.36	RP11-109E24.2		26187	0.21
chr6_170892964_170893222	0.36	PDCD2	programmed cell death 2	221	0.94
chr15_49598726_49598877	0.36	GALK2	galactokinase 2	13078	0.23
chr7_158989345_158989650	0.36	VIPR2	vasoactive intestinal peptide receptor 2	51848	0.18
chr1_25656039_25656190	0.35	TMEM50A	transmembrane protein 50A	8294	0.13
chr11_114044267_114044465	0.35	NNMT	nicotinamide N-methyltransferase	84187	0.08
chr7_115666493_115666644	0.35	TFEC	transcription factor EC	4227	0.35
chr13_74806232_74806383	0.35	ENSG00000206617	.	57044	0.16
chr5_107008434_107008585	0.35	EFNA5	ephrin-A5	1913	0.47
chr22_40926921_40927072	0.35	MKL1	megakaryoblastic leukemia (translocation) 1	2819	0.22
chr15_62336780_62336931	0.34	VPS13C	vacuolar protein sorting 13 homolog C (S. cerevisiae)	15792	0.18
chr11_75535033_75535184	0.34	RP11-535A19.2		8657	0.1
chr4_114647853_114648004	0.34	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	34296	0.24
chr12_51765317_51765530	0.34	GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	11924	0.15
chr14_61876766_61876917	0.34	PRKCH	protein kinase C, eta	19429	0.23
chr5_110570725_110571085	0.34	CAMK4	calcium/calmodulin-dependent protein kinase IV	11121	0.22
chr4_15644909_15645060	0.34	FBXL5	F-box and leucine-rich repeat protein 5	1288	0.49
chr6_41039160_41039461	0.34	OARD1	O-acyl-ADP-ribose deacylase 1	269	0.83
chr13_24842364_24842558	0.34	SPATA13	spermatogenesis associated 13	2365	0.26
chr1_151761608_151761759	0.34	TDRKH	tudor and KH domain containing	1223	0.2
chr4_67058513_67058664	0.33	ENSG00000221563	.	83954	0.11
chr2_201724504_201724705	0.33	CLK1	CDC-like kinase 1	1715	0.18
chr8_129604479_129604630	0.33	ENSG00000221351	.	227486	0.02
chr2_68470770_68470921	0.33	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	7435	0.14
chrX_1699314_1699465	0.33	AKAP17A	A kinase (PRKA) anchor protein 17A	11097	0.2
chr3_59997046_59997753	0.33	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	39816	0.23
chr9_6002561_6002712	0.33	KIAA2026	KIAA2026	5151	0.19
chr12_6257414_6257620	0.33	VWF	von Willebrand factor	23676	0.17
chr6_52151518_52151818	0.33	MCM3	minichromosome maintenance complex component 3	2033	0.36
chr17_14054887_14055038	0.33	ENSG00000252305	.	25486	0.19
chr5_80584060_80584211	0.33	CKMT2-AS1	CKMT2 antisense RNA 1	13169	0.2
chrX_77578325_77578530	0.33	CYSLTR1	cysteinyl leukotriene receptor 1	4553	0.35
chr5_109191395_109191546	0.33	AC011366.3	Uncharacterized protein	27413	0.25
chr13_74560551_74560702	0.33	KLF12	Kruppel-like factor 12	8560	0.33
chr8_8702814_8703117	0.33	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	48190	0.14
chr6_112348738_112349139	0.33	WISP3	WNT1 inducible signaling pathway protein 3	26337	0.19
chr10_103561287_103561527	0.33	MGEA5	meningioma expressed antigen 5 (hyaluronidase)	16216	0.13
chr14_75304708_75304859	0.33	RP11-316E14.6		5944	0.16
chr15_63446100_63446251	0.33	RPS27L	ribosomal protein S27-like	2798	0.26
chr1_33813799_33814177	0.33	PHC2	polyhomeotic homolog 2 (Drosophila)	1498	0.26
chrX_123478016_123478167	0.33	SH2D1A	SH2 domain containing 1A	2103	0.47
chr6_149415552_149415836	0.33	RP11-162J8.3		61985	0.12
chr22_31922063_31922214	0.33	SFI1	Sfi1 homolog, spindle assembly associated (yeast)	2593	0.24
chr3_56759034_56759351	0.33	FAM208A	family with sequence similarity 208, member A	41927	0.17
chr19_14104811_14104962	0.32	RFX1	regulatory factor X, 1 (influences HLA class II expression)	12188	0.1
chr3_125073758_125073909	0.32	ZNF148	zinc finger protein 148	2291	0.32
chr10_17717786_17717937	0.32	ENSG00000251959	.	3326	0.21
chr4_110483501_110483678	0.32	CCDC109B	coiled-coil domain containing 109B	1443	0.48
chr3_16959852_16960003	0.32	PLCL2	phospholipase C-like 2	14655	0.22
chr4_123142440_123142597	0.32	KIAA1109	KIAA1109	1894	0.48
chr1_101548668_101549086	0.32	RP11-421L21.3		10661	0.19
chr2_26058549_26058700	0.32	ASXL2	additional sex combs like 2 (Drosophila)	42711	0.17
chr4_54924725_54924876	0.32	AC110792.1	HCG2027126; Uncharacterized protein	2413	0.26
chr4_90213174_90213336	0.32	GPRIN3	GPRIN family member 3	15906	0.29
chr9_18429431_18429582	0.32	ADAMTSL1	ADAMTS-like 1	44386	0.2
chr11_116796998_116797221	0.32	SIK3	SIK family kinase 3	30651	0.13
chr2_42410408_42410655	0.32	AC083949.1		13090	0.22
chr3_52315744_52316277	0.32	WDR82	WD repeat domain 82	3351	0.11
chr6_90545610_90545797	0.32	ENSG00000199630	.	5345	0.17
chr10_31149530_31149681	0.32	ZNF438	zinc finger protein 438	2990	0.33
chr1_154444184_154444335	0.32	RP11-350G8.9		8229	0.12
chr2_66749975_66750126	0.32	MEIS1	Meis homeobox 1	13991	0.25
chr5_31972932_31973083	0.32	ENSG00000266243	.	36742	0.17
chr19_35697571_35697754	0.32	FAM187B	family with sequence similarity 187, member B	21970	0.09
chr3_151915054_151915675	0.32	MBNL1	muscleblind-like splicing regulator 1	70465	0.11
chr12_47756713_47756864	0.32	ENSG00000264906	.	1264	0.51
chr17_33593624_33593920	0.31	SLFN5	schlafen family member 5	23664	0.14
chr7_125200492_125200777	0.31	ENSG00000221418	.	479649	0.01
chr21_19162310_19162577	0.31	AL109761.5		3362	0.29
chr4_26918585_26918736	0.31	STIM2	stromal interaction molecule 2	55579	0.15
chr5_14831740_14832005	0.31	ENSG00000264792	.	5751	0.26
chr6_149698924_149699075	0.31	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	7955	0.2
chr11_121318869_121319068	0.31	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	3944	0.27
chr6_143186229_143186520	0.31	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	28190	0.23
chr3_71543419_71543780	0.31	ENSG00000221264	.	47641	0.15
chr10_17703046_17703197	0.31	STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	16857	0.14
chr2_190459215_190459366	0.31	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	10806	0.22
chrY_1649313_1649464	0.31	NA	NA	> 10⁶	NA
chr4_36257679_36258065	0.31	RP11-431M7.3		268	0.93
chr3_32943774_32943925	0.31	CCR4	chemokine (C-C motif) receptor 4	49217	0.15
chr15_91142697_91142929	0.31	CTD-3065B20.2		3134	0.2
chr16_50370578_50370742	0.31	ENSG00000238544	.	15543	0.16
chr15_56533645_56533860	0.31	RFX7	regulatory factor X, 7	1712	0.35
chr11_71742340_71742491	0.31	NUMA1	nuclear mitotic apparatus protein 1	8456	0.1
chr10_4015624_4015927	0.31	KLF6	Kruppel-like factor 6	188302	0.03
chr1_32965903_32966087	0.31	ZBTB8B	zinc finger and BTB domain containing 8B	35325	0.12
chr8_42587750_42588047	0.31	RP11-412B14.1		10809	0.18
chr10_112751573_112751724	0.31	ENSG00000221214	.	2964	0.26
chr14_98871416_98871598	0.31	ENSG00000241757	.	53506	0.16
chr4_185627591_185627742	0.31	CENPU	centromere protein U	26902	0.16
chr2_68385602_68386003	0.31	PNO1	partner of NOB1 homolog (S. cerevisiae)	826	0.45
chr4_99561301_99561452	0.30	TSPAN5	tetraspanin 5	17410	0.22
chr1_65530504_65530655	0.30	ENSG00000199135	.	6388	0.2
chrX_78414738_78414977	0.30	GPR174	G protein-coupled receptor 174	11612	0.31
chr1_193447704_193447855	0.30	ENSG00000252241	.	253295	0.02
chr4_41884592_41884743	0.30	TMEM33	transmembrane protein 33	52470	0.14
chr15_100064853_100065269	0.30	AC015660.1	HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein	26483	0.19
chr16_3183094_3183251	0.30	RP11-473M20.14		822	0.34
chr10_5845619_5845770	0.30	GDI2	GDP dissociation inhibitor 2	9656	0.2
chr14_21567299_21567458	0.30	ZNF219	zinc finger protein 219	205	0.57
chr1_192574625_192574776	0.30	RGS1	regulator of G-protein signaling 1	29797	0.17
chr3_88112020_88112171	0.30	RP11-159G9.5	Uncharacterized protein	3671	0.23
chr6_154561193_154561344	0.30	IPCEF1	interaction protein for cytohesin exchange factors 1	6722	0.33
chr11_14722661_14722840	0.30	PDE3B	phosphodiesterase 3B, cGMP-inhibited	57373	0.14
chr14_92264713_92264864	0.30	TC2N	tandem C2 domains, nuclear	554	0.77
chr2_237276397_237276583	0.30	RP11-785G17.1		287	0.92
chr14_99721349_99721548	0.30	AL109767.1		7837	0.22
chr10_32625748_32625899	0.30	RP11-135A24.4		9604	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.4	GO:0035987	endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.1	GO:2000696	nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.1	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.4	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.3	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.1	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.5	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	1.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.2	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.2	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.3	GO:0050856	regulation of T cell receptor signaling pathway(GO:0050856)
0.0	0.2	GO:2000351	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.3	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.5	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.5	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.2	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0010759	regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	1.4	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0090197	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.2	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.0	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.2	GO:0032653	regulation of interleukin-10 production(GO:0032653)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.4	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0034776	response to histamine(GO:0034776)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.2	GO:0035637	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0042711	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0033083	regulation of immature T cell proliferation(GO:0033083)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.3	GO:0046134	pyrimidine nucleoside biosynthetic process(GO:0046134)
0.0	0.0	GO:0071548	response to dexamethasone(GO:0071548)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976) activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.5	GO:0022616	DNA strand elongation(GO:0022616)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0072273	metanephric nephron morphogenesis(GO:0072273)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.1	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.2	GO:1905037	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0070092	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.2	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.2	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.2	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:1901070	GMP biosynthetic process(GO:0006177) guanosine-containing compound biosynthetic process(GO:1901070)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.2	GO:0033014	tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.1	GO:0052646	alditol phosphate metabolic process(GO:0052646)
0.0	0.0	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.0	GO:0009220	pyrimidine ribonucleotide biosynthetic process(GO:0009220)
0.0	0.1	GO:0042991	regulation of transcription factor import into nucleus(GO:0042990) transcription factor import into nucleus(GO:0042991)
0.0	0.3	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
0.0	0.1	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.0	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0048895	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.0	GO:0031033	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.4	GO:0032155	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.4	GO:0009295	nucleoid(GO:0009295)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0000791	euchromatin(GO:0000791)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.4	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	1.1	GO:0016607	nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.4	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	1.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.5	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	1.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.0	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.4	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.4	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.0	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.5	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.0	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.0	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.3	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0015605	organophosphate ester transmembrane transporter activity(GO:0015605)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.6	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.9	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.8	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.6	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.0	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.0	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Results for ALX1_ARX

Z-value: 0.90

Motif logo

Transcription factors associated with ALX1_ARX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ALX1_ARX motif across conditions

Conditions sorted by the z-value of the ALX1_ARX motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: