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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ALX1_ARX

Z-value: 0.90

Motif logo

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ENSG00000180318.3 ALX1
ENSG00000004848.6 ARX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ALX1chr12_85799990_858001411261800.059739-0.472.0e-01Click!
ALX1chr12_85856935_858570861831250.0312160.393.0e-01Click!
ALX1chr12_85673428_856735793820.924685-0.324.1e-01Click!
ALX1chr12_85667489_8566764063210.326447-0.314.2e-01Click!
ALX1chr12_85667282_8566743365280.324781-0.284.6e-01Click!
ARXchrX_25024484_2502463595060.273047-0.742.3e-02Click!
ARXchrX_25038619_2503883946640.2960080.723.0e-02Click!
ARXchrX_25023685_25023935102550.271076-0.684.2e-02Click!
ARXchrX_25041076_2504122770860.2710670.674.8e-02Click!
ARXchrX_25035659_2503611818230.4536730.646.6e-02Click!

Activity of the ALX1_ARX motif across conditions

Conditions sorted by the z-value of the ALX1_ARX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_146046169_146046320 0.70 ENSG00000238713
.
24557
0.16
chr12_94166165_94166316 0.70 RP11-887P2.5

34641
0.16
chr20_35573807_35573970 0.68 SAMHD1
SAM domain and HD domain 1
6223
0.23
chr2_172067040_172067353 0.67 TLK1
tousled-like kinase 1
20628
0.24
chr10_97723999_97724150 0.67 CC2D2B
coiled-coil and C2 domain containing 2B
9712
0.17
chr17_46530677_46530986 0.63 SKAP1
src kinase associated phosphoprotein 1
23250
0.11
chr6_16437826_16437977 0.63 ENSG00000265642
.
9147
0.31
chrX_135818033_135818184 0.60 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
31394
0.15
chr10_33443500_33443690 0.60 NRP1
neuropilin 1
30988
0.18
chr20_43600993_43601244 0.59 STK4
serine/threonine kinase 4
5951
0.16
chr6_149829598_149829769 0.59 ENSG00000252244
.
8409
0.14
chr1_185646684_185647143 0.58 ENSG00000201596
.
43599
0.15
chr3_94093717_94093868 0.57 ENSG00000253062
.
276382
0.01
chr14_61872843_61873172 0.57 PRKCH
protein kinase C, eta
15595
0.24
chr11_46653734_46653885 0.54 HARBI1
harbinger transposase derived 1
14350
0.14
chr3_98291649_98291800 0.53 CPOX
coproporphyrinogen oxidase
20843
0.14
chr6_53206539_53206690 0.53 ELOVL5
ELOVL fatty acid elongase 5
6973
0.22
chr8_59977677_59977828 0.52 RP11-25K19.1

53847
0.13
chr4_78000086_78000237 0.50 CCNI
cyclin I
3003
0.3
chr3_170983485_170983636 0.50 TNIK
TRAF2 and NCK interacting kinase
40060
0.2
chr1_65475101_65475369 0.50 ENSG00000212257
.
13522
0.19
chr15_75414732_75414883 0.49 ENSG00000252722
.
800
0.61
chr7_50462451_50462702 0.49 ENSG00000200815
.
40502
0.17
chr3_53788532_53788827 0.49 CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
5572
0.22
chrX_41553097_41553277 0.49 GPR34
G protein-coupled receptor 34
4928
0.2
chr11_118573475_118573626 0.48 ENSG00000207462
.
499
0.68
chr5_72795152_72795340 0.47 BTF3
basic transcription factor 3
911
0.58
chr12_106979257_106979408 0.47 RFX4
regulatory factor X, 4 (influences HLA class II expression)
173
0.97
chr7_21482045_21482196 0.46 SP4
Sp4 transcription factor
14459
0.18
chr10_17548800_17549076 0.46 ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
52609
0.13
chr14_70096957_70097157 0.45 KIAA0247
KIAA0247
18744
0.22
chr5_79519389_79519540 0.45 ENSG00000239159
.
15944
0.19
chr1_185643113_185643264 0.45 ENSG00000201596
.
39874
0.16
chrX_153389909_153390065 0.45 OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
19711
0.12
chr9_33075698_33075952 0.44 SMU1
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
832
0.59
chr22_31667328_31667479 0.44 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
20978
0.09
chr7_37329474_37329753 0.44 ELMO1
engulfment and cell motility 1
52754
0.14
chrX_15779492_15779655 0.44 CA5B
carbonic anhydrase VB, mitochondrial
11480
0.18
chr15_41956228_41956379 0.44 MGA
MGA, MAX dimerization protein
3693
0.22
chr3_157824510_157824697 0.43 SHOX2
short stature homeobox 2
311
0.83
chr1_66648150_66648486 0.43 PDE4B
phosphodiesterase 4B, cAMP-specific
30245
0.23
chr9_123961014_123961178 0.43 RAB14
RAB14, member RAS oncogene family
3051
0.2
chr12_94600310_94600885 0.43 RP11-74K11.2

20777
0.19
chr21_45440771_45440922 0.43 TRAPPC10
trafficking protein particle complex 10
8646
0.18
chr1_169547776_169547927 0.42 F5
coagulation factor V (proaccelerin, labile factor)
7868
0.22
chr1_114393077_114393228 0.42 AP4B1-AS1
AP4B1 antisense RNA 1
6105
0.14
chr4_148973362_148973513 0.42 RP11-76G10.1

94185
0.09
chr17_64310479_64310630 0.42 PRKCA
protein kinase C, alpha
11610
0.2
chr4_109029927_109030290 0.42 LEF1
lymphoid enhancer-binding factor 1
57349
0.12
chr1_209957444_209957681 0.42 C1orf74
chromosome 1 open reading frame 74
342
0.82
chr3_120163660_120163960 0.41 FSTL1
follistatin-like 1
6028
0.28
chr4_39035740_39035891 0.41 TMEM156
transmembrane protein 156
1273
0.48
chr3_197339250_197339401 0.41 AC024560.3

15394
0.19
chr10_60426464_60426615 0.40 BICC1
bicaudal C homolog 1 (Drosophila)
126756
0.06
chr4_96138306_96138502 0.40 BMPR1B
bone morphogenetic protein receptor, type IB
112898
0.07
chr3_18470958_18471238 0.40 SATB1
SATB homeobox 1
4237
0.24
chr10_8102007_8102158 0.40 GATA3
GATA binding protein 3
5313
0.35
chr3_187717065_187717289 0.40 LPP
LIM domain containing preferred translocation partner in lipoma
153895
0.04
chr13_28729339_28729490 0.40 PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
16244
0.18
chr1_225654690_225654867 0.40 RP11-496N12.6

1733
0.4
chr1_19933625_19933816 0.40 MINOS1-NBL1
MINOS1-NBL1 readthrough
10159
0.13
chr1_211526157_211526486 0.39 TRAF5
TNF receptor-associated factor 5
6615
0.27
chr22_45614758_45614909 0.39 KIAA0930
KIAA0930
5453
0.18
chr2_24953254_24953405 0.39 ENSG00000206732
.
54151
0.11
chr10_17274804_17274955 0.39 RP11-124N14.3

1953
0.24
chr9_96227227_96227603 0.39 FAM120AOS
family with sequence similarity 120A opposite strand
11541
0.14
chr17_28066618_28066769 0.39 RP11-82O19.1

21428
0.14
chr2_225897343_225897494 0.38 DOCK10
dedicator of cytokinesis 10
9741
0.26
chr13_41339497_41339648 0.38 MRPS31
mitochondrial ribosomal protein S31
5737
0.19
chr12_92691247_92691679 0.38 RP11-693J15.4

123844
0.05
chr15_45029426_45029577 0.38 TRIM69
tripartite motif containing 69
737
0.62
chr12_52645458_52645609 0.38 KRT86
keratin 86
2449
0.15
chr1_25969522_25969744 0.38 RP1-187B23.1

15969
0.18
chr2_203395606_203395757 0.38 FAM117B
family with sequence similarity 117, member B
104220
0.06
chr6_35638568_35638782 0.38 ENSG00000265527
.
6109
0.15
chrX_1699864_1700015 0.37 AKAP17A
A kinase (PRKA) anchor protein 17A
10547
0.21
chrX_41117068_41117219 0.37 RP5-1172N10.4

24257
0.17
chr6_144713753_144713904 0.37 UTRN
utrophin
48591
0.17
chr16_53578586_53578737 0.37 AKTIP
AKT interacting protein
40338
0.16
chrY_1649865_1650016 0.37 NA
NA
> 106
NA
chr13_47243748_47243899 0.37 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
10148
0.29
chr6_2893026_2893177 0.37 SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
10413
0.18
chr9_123694906_123695182 0.37 TRAF1
TNF receptor-associated factor 1
3593
0.27
chr1_100863756_100864116 0.37 ENSG00000216067
.
19605
0.19
chr20_32828478_32828629 0.37 ASIP
agouti signaling protein
19618
0.16
chr4_183839462_183839895 0.36 DCTD
dCMP deaminase
589
0.83
chr5_130730727_130730878 0.36 CDC42SE2
CDC42 small effector 2
9503
0.3
chr6_143189800_143189951 0.36 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
31691
0.22
chr3_15380688_15380839 0.36 ENSG00000201162
.
493
0.72
chr10_111776073_111776241 0.36 ADD3
adducin 3 (gamma)
8435
0.21
chr2_231517982_231518133 0.36 CAB39
calcium binding protein 39
59503
0.11
chr2_205812915_205813103 0.36 PARD3B
par-3 family cell polarity regulator beta
402286
0.01
chr4_42685625_42685776 0.36 RP11-109E24.2

26187
0.21
chr6_170892964_170893222 0.36 PDCD2
programmed cell death 2
221
0.94
chr15_49598726_49598877 0.36 GALK2
galactokinase 2
13078
0.23
chr7_158989345_158989650 0.36 VIPR2
vasoactive intestinal peptide receptor 2
51848
0.18
chr1_25656039_25656190 0.35 TMEM50A
transmembrane protein 50A
8294
0.13
chr11_114044267_114044465 0.35 NNMT
nicotinamide N-methyltransferase
84187
0.08
chr7_115666493_115666644 0.35 TFEC
transcription factor EC
4227
0.35
chr13_74806232_74806383 0.35 ENSG00000206617
.
57044
0.16
chr5_107008434_107008585 0.35 EFNA5
ephrin-A5
1913
0.47
chr22_40926921_40927072 0.35 MKL1
megakaryoblastic leukemia (translocation) 1
2819
0.22
chr15_62336780_62336931 0.34 VPS13C
vacuolar protein sorting 13 homolog C (S. cerevisiae)
15792
0.18
chr11_75535033_75535184 0.34 RP11-535A19.2

8657
0.1
chr4_114647853_114648004 0.34 CAMK2D
calcium/calmodulin-dependent protein kinase II delta
34296
0.24
chr12_51765317_51765530 0.34 GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
11924
0.15
chr14_61876766_61876917 0.34 PRKCH
protein kinase C, eta
19429
0.23
chr5_110570725_110571085 0.34 CAMK4
calcium/calmodulin-dependent protein kinase IV
11121
0.22
chr4_15644909_15645060 0.34 FBXL5
F-box and leucine-rich repeat protein 5
1288
0.49
chr6_41039160_41039461 0.34 OARD1
O-acyl-ADP-ribose deacylase 1
269
0.83
chr13_24842364_24842558 0.34 SPATA13
spermatogenesis associated 13
2365
0.26
chr1_151761608_151761759 0.34 TDRKH
tudor and KH domain containing
1223
0.2
chr4_67058513_67058664 0.33 ENSG00000221563
.
83954
0.11
chr2_201724504_201724705 0.33 CLK1
CDC-like kinase 1
1715
0.18
chr8_129604479_129604630 0.33 ENSG00000221351
.
227486
0.02
chr2_68470770_68470921 0.33 PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
7435
0.14
chrX_1699314_1699465 0.33 AKAP17A
A kinase (PRKA) anchor protein 17A
11097
0.2
chr3_59997046_59997753 0.33 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
39816
0.23
chr9_6002561_6002712 0.33 KIAA2026
KIAA2026
5151
0.19
chr12_6257414_6257620 0.33 VWF
von Willebrand factor
23676
0.17
chr6_52151518_52151818 0.33 MCM3
minichromosome maintenance complex component 3
2033
0.36
chr17_14054887_14055038 0.33 ENSG00000252305
.
25486
0.19
chr5_80584060_80584211 0.33 CKMT2-AS1
CKMT2 antisense RNA 1
13169
0.2
chrX_77578325_77578530 0.33 CYSLTR1
cysteinyl leukotriene receptor 1
4553
0.35
chr5_109191395_109191546 0.33 AC011366.3
Uncharacterized protein
27413
0.25
chr13_74560551_74560702 0.33 KLF12
Kruppel-like factor 12
8560
0.33
chr8_8702814_8703117 0.33 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
48190
0.14
chr6_112348738_112349139 0.33 WISP3
WNT1 inducible signaling pathway protein 3
26337
0.19
chr10_103561287_103561527 0.33 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
16216
0.13
chr14_75304708_75304859 0.33 RP11-316E14.6

5944
0.16
chr15_63446100_63446251 0.33 RPS27L
ribosomal protein S27-like
2798
0.26
chr1_33813799_33814177 0.33 PHC2
polyhomeotic homolog 2 (Drosophila)
1498
0.26
chrX_123478016_123478167 0.33 SH2D1A
SH2 domain containing 1A
2103
0.47
chr6_149415552_149415836 0.33 RP11-162J8.3

61985
0.12
chr22_31922063_31922214 0.33 SFI1
Sfi1 homolog, spindle assembly associated (yeast)
2593
0.24
chr3_56759034_56759351 0.33 FAM208A
family with sequence similarity 208, member A
41927
0.17
chr19_14104811_14104962 0.32 RFX1
regulatory factor X, 1 (influences HLA class II expression)
12188
0.1
chr3_125073758_125073909 0.32 ZNF148
zinc finger protein 148
2291
0.32
chr10_17717786_17717937 0.32 ENSG00000251959
.
3326
0.21
chr4_110483501_110483678 0.32 CCDC109B
coiled-coil domain containing 109B
1443
0.48
chr3_16959852_16960003 0.32 PLCL2
phospholipase C-like 2
14655
0.22
chr4_123142440_123142597 0.32 KIAA1109
KIAA1109
1894
0.48
chr1_101548668_101549086 0.32 RP11-421L21.3

10661
0.19
chr2_26058549_26058700 0.32 ASXL2
additional sex combs like 2 (Drosophila)
42711
0.17
chr4_54924725_54924876 0.32 AC110792.1
HCG2027126; Uncharacterized protein
2413
0.26
chr4_90213174_90213336 0.32 GPRIN3
GPRIN family member 3
15906
0.29
chr9_18429431_18429582 0.32 ADAMTSL1
ADAMTS-like 1
44386
0.2
chr11_116796998_116797221 0.32 SIK3
SIK family kinase 3
30651
0.13
chr2_42410408_42410655 0.32 AC083949.1

13090
0.22
chr3_52315744_52316277 0.32 WDR82
WD repeat domain 82
3351
0.11
chr6_90545610_90545797 0.32 ENSG00000199630
.
5345
0.17
chr10_31149530_31149681 0.32 ZNF438
zinc finger protein 438
2990
0.33
chr1_154444184_154444335 0.32 RP11-350G8.9

8229
0.12
chr2_66749975_66750126 0.32 MEIS1
Meis homeobox 1
13991
0.25
chr5_31972932_31973083 0.32 ENSG00000266243
.
36742
0.17
chr19_35697571_35697754 0.32 FAM187B
family with sequence similarity 187, member B
21970
0.09
chr3_151915054_151915675 0.32 MBNL1
muscleblind-like splicing regulator 1
70465
0.11
chr12_47756713_47756864 0.32 ENSG00000264906
.
1264
0.51
chr17_33593624_33593920 0.31 SLFN5
schlafen family member 5
23664
0.14
chr7_125200492_125200777 0.31 ENSG00000221418
.
479649
0.01
chr21_19162310_19162577 0.31 AL109761.5

3362
0.29
chr4_26918585_26918736 0.31 STIM2
stromal interaction molecule 2
55579
0.15
chr5_14831740_14832005 0.31 ENSG00000264792
.
5751
0.26
chr6_149698924_149699075 0.31 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
7955
0.2
chr11_121318869_121319068 0.31 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
3944
0.27
chr6_143186229_143186520 0.31 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
28190
0.23
chr3_71543419_71543780 0.31 ENSG00000221264
.
47641
0.15
chr10_17703046_17703197 0.31 STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
16857
0.14
chr2_190459215_190459366 0.31 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
10806
0.22
chrY_1649313_1649464 0.31 NA
NA
> 106
NA
chr4_36257679_36258065 0.31 RP11-431M7.3

268
0.93
chr3_32943774_32943925 0.31 CCR4
chemokine (C-C motif) receptor 4
49217
0.15
chr15_91142697_91142929 0.31 CTD-3065B20.2

3134
0.2
chr16_50370578_50370742 0.31 ENSG00000238544
.
15543
0.16
chr15_56533645_56533860 0.31 RFX7
regulatory factor X, 7
1712
0.35
chr11_71742340_71742491 0.31 NUMA1
nuclear mitotic apparatus protein 1
8456
0.1
chr10_4015624_4015927 0.31 KLF6
Kruppel-like factor 6
188302
0.03
chr1_32965903_32966087 0.31 ZBTB8B
zinc finger and BTB domain containing 8B
35325
0.12
chr8_42587750_42588047 0.31 RP11-412B14.1

10809
0.18
chr10_112751573_112751724 0.31 ENSG00000221214
.
2964
0.26
chr14_98871416_98871598 0.31 ENSG00000241757
.
53506
0.16
chr4_185627591_185627742 0.31 CENPU
centromere protein U
26902
0.16
chr2_68385602_68386003 0.31 PNO1
partner of NOB1 homolog (S. cerevisiae)
826
0.45
chr4_99561301_99561452 0.30 TSPAN5
tetraspanin 5
17410
0.22
chr1_65530504_65530655 0.30 ENSG00000199135
.
6388
0.2
chrX_78414738_78414977 0.30 GPR174
G protein-coupled receptor 174
11612
0.31
chr1_193447704_193447855 0.30 ENSG00000252241
.
253295
0.02
chr4_41884592_41884743 0.30 TMEM33
transmembrane protein 33
52470
0.14
chr15_100064853_100065269 0.30 AC015660.1
HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
26483
0.19
chr16_3183094_3183251 0.30 RP11-473M20.14

822
0.34
chr10_5845619_5845770 0.30 GDI2
GDP dissociation inhibitor 2
9656
0.2
chr14_21567299_21567458 0.30 ZNF219
zinc finger protein 219
205
0.57
chr1_192574625_192574776 0.30 RGS1
regulator of G-protein signaling 1
29797
0.17
chr3_88112020_88112171 0.30 RP11-159G9.5
Uncharacterized protein
3671
0.23
chr6_154561193_154561344 0.30 IPCEF1
interaction protein for cytohesin exchange factors 1
6722
0.33
chr11_14722661_14722840 0.30 PDE3B
phosphodiesterase 3B, cGMP-inhibited
57373
0.14
chr14_92264713_92264864 0.30 TC2N
tandem C2 domains, nuclear
554
0.77
chr2_237276397_237276583 0.30 RP11-785G17.1

287
0.92
chr14_99721349_99721548 0.30 AL109767.1

7837
0.22
chr10_32625748_32625899 0.30 RP11-135A24.4

9604
0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ALX1_ARX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1 0.4 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.1 GO:2000696 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.1 0.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.2 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.3 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.2 GO:2000351 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.3 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.5 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0090197 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.2 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.2 GO:0032653 regulation of interleukin-10 production(GO:0032653)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.0 GO:0034776 response to histamine(GO:0034776)
0.0 0.0 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.2 GO:0035637 transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0033083 regulation of immature T cell proliferation(GO:0033083)
0.0 0.1 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.2 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.3 GO:0046134 pyrimidine nucleoside biosynthetic process(GO:0046134)
0.0 0.0 GO:0071548 response to dexamethasone(GO:0071548)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0042976 activation of Janus kinase activity(GO:0042976) activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.5 GO:0022616 DNA strand elongation(GO:0022616)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0072273 metanephric nephron morphogenesis(GO:0072273)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 0.1 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.0 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:1900181 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0 0.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:1901070 GMP biosynthetic process(GO:0006177) guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0033014 tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.0 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.0 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:0009220 pyrimidine ribonucleotide biosynthetic process(GO:0009220)
0.0 0.1 GO:0042991 regulation of transcription factor import into nucleus(GO:0042990) transcription factor import into nucleus(GO:0042991)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.1 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.0 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0048895 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0031033 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0032155 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0009295 nucleoid(GO:0009295)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.1 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.5 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.0 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.0 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis