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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ATF7

Z-value: 0.90

Motif logo

Transcription factors associated with ATF7

Gene Symbol	Gene ID	Gene Info
ATF7 Ensembl NCBI GeneCards UniProt	ENSG00000170653.14	ATF7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ATF7	chr12_53964156_53964307	30574	0.109163	0.74	2.2e-02	Click!
ATF7	chr12_53989142_53989293	5588	0.168089	0.74	2.3e-02	Click!
ATF7	chr12_54017496_54017647	2184	0.226720	0.74	2.4e-02	Click!
ATF7	chr12_53969438_53969764	25204	0.121145	0.72	2.9e-02	Click!
ATF7	chr12_53969924_53970134	24776	0.122080	0.71	3.2e-02	Click!

Activity of the ATF7 motif across conditions

Conditions sorted by the z-value of the ATF7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_141015090_141015375	0.64	RP11-392B6.1		33937	0.2
chr6_80714655_80715350	0.61	TTK	TTK protein kinase	451	0.88
chr5_14264414_14265476	0.60	TRIO	trio Rho guanine nucleotide exchange factor	26141	0.27
chr1_56981894_56982239	0.59	PPAP2B	phosphatidic acid phosphatase type 2B	63175	0.14
chr12_133022629_133022780	0.57	MUC8	mucin 8	28022	0.17
chr2_8552253_8552511	0.57	AC011747.7		263514	0.02
chr5_73730230_73730381	0.53	ENSG00000244326	.	116494	0.06
chr15_40636361_40636512	0.53	C15orf52	chromosome 15 open reading frame 52	3268	0.1
chr11_12695755_12695947	0.52	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	118	0.98
chr6_64516560_64517136	0.52	RP11-59D5__B.2		119	0.98
chr6_14477462_14477818	0.51	ENSG00000206960	.	169126	0.04
chr17_65505786_65506259	0.51	CTD-2653B5.1		14575	0.17
chr21_44937001_44937451	0.50	SIK1	salt-inducible kinase 1	90218	0.08
chr16_31141784_31142119	0.50	RP11-388M20.2		803	0.33
chr12_8043408_8043946	0.47	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	67	0.95
chr6_2449367_2449525	0.47	ENSG00000266252	.	39577	0.21
chr1_181056660_181057120	0.46	IER5	immediate early response 5	748	0.71
chr4_74575921_74576072	0.44	IL8	interleukin 8	30227	0.19
chr5_179453537_179453707	0.44	ENSG00000198995	.	11225	0.19
chr14_75655646_75655840	0.44	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	12409	0.15
chr7_100782348_100782499	0.44	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	12044	0.1
chr10_6959147_6959298	0.42	PRKCQ	protein kinase C, theta	336959	0.01
chr1_17630639_17630914	0.42	PADI4	peptidyl arginine deiminase, type IV	3914	0.2
chr9_130912677_130912874	0.41	LCN2	lipocalin 2	978	0.34
chr1_22380057_22380208	0.40	CDC42	cell division cycle 42	342	0.82
chr22_44569121_44569281	0.39	PARVG	parvin, gamma	365	0.92
chr8_62625004_62625155	0.39	ASPH	aspartate beta-hydroxylase	2005	0.33
chr11_65256298_65256486	0.38	AP000769.1	Uncharacterized protein	33664	0.08
chr4_153913148_153913299	0.37	FHDC1	FH2 domain containing 1	49088	0.16
chr8_61896258_61896409	0.36	CLVS1	clavesin 1	73384	0.12
chr17_25773754_25774039	0.36	KSR1	kinase suppressor of ras 1	9774	0.19
chr2_28114153_28114304	0.36	RBKS	ribokinase	263	0.74
chr15_49336349_49337349	0.36	SECISBP2L	SECIS binding protein 2-like	1781	0.28
chr6_18403082_18403233	0.36	ENSG00000238458	.	874	0.65
chr17_55446479_55446630	0.36	ENSG00000263902	.	43008	0.17
chr17_42423914_42424082	0.36	GRN	granulin	1325	0.25
chr3_99721724_99721891	0.36	ENSG00000264897	.	38565	0.19
chr2_108994281_108994432	0.35	SULT1C4	sulfotransferase family, cytosolic, 1C, member 4	112	0.97
chr9_111578900_111579091	0.35	ACTL7B	actin-like 7B	40244	0.16
chr18_10791557_10791762	0.35	PIEZO2	piezo-type mechanosensitive ion channel component 2	11	0.99
chr17_61723267_61723570	0.35	MAP3K3	mitogen-activated protein kinase kinase kinase 3	23348	0.13
chr12_6187508_6187659	0.35	ENSG00000240533	.	17553	0.21
chr10_11628107_11628334	0.34	USP6NL	USP6 N-terminal like	12380	0.23
chr2_197944933_197945147	0.33	ANKRD44	ankyrin repeat domain 44	30528	0.22
chr17_42978313_42978555	0.33	CCDC103	coiled-coil domain containing 103	1292	0.19
chr13_99234265_99234566	0.32	STK24-AS1	STK24 antisense RNA 1	4917	0.23
chr13_97876107_97876342	0.32	MBNL2	muscleblind-like splicing regulator 2	1615	0.53
chr8_48393092_48393308	0.32	SPIDR	scaffolding protein involved in DNA repair	40237	0.18
chr2_8144515_8144736	0.32	ENSG00000221255	.	427653	0.01
chr18_20840672_20840823	0.31	RP11-17J14.2		429	0.89
chr20_36797041_36797355	0.31	TGM2	transglutaminase 2	2218	0.32
chr8_49838453_49838744	0.31	SNAI2	snail family zinc finger 2	4299	0.35
chr6_53213778_53213929	0.31	ELOVL5	ELOVL fatty acid elongase 5	48	0.98
chr16_70730831_70731276	0.31	VAC14	Vac14 homolog (S. cerevisiae)	1557	0.31
chr5_102729544_102729916	0.31	C5orf30	chromosome 5 open reading frame 30	134605	0.05
chr7_132095239_132095390	0.30	AC011625.1		58221	0.15
chr10_103143872_103144023	0.30	ENSG00000239091	.	12238	0.16
chr16_73087544_73087838	0.30	ZFHX3	zinc finger homeobox 3	5417	0.25
chr1_113361578_113361925	0.30	FAM19A3	family with sequence similarity 19 (chemokine (C-C motif)-like), member A3	98552	0.05
chr4_38822000_38822151	0.30	TLR6	toll-like receptor 6	9085	0.16
chr14_73927648_73927878	0.30	ENSG00000251393	.	1366	0.34
chr12_124983629_124983780	0.30	NCOR2	nuclear receptor corepressor 2	3906	0.36
chr17_18528921_18529072	0.30	CCDC144B	coiled-coil domain containing 144B (pseudogene)	75	0.96
chr11_13238293_13238470	0.30	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	59818	0.15
chr4_159131101_159131306	0.29	TMEM144	transmembrane protein 144	143	0.96
chr18_22820121_22820315	0.29	ZNF521	zinc finger protein 521	8724	0.3
chr15_91040083_91040234	0.29	CRTC3	CREB regulated transcription coactivator 3	32999	0.15
chr3_159571102_159571298	0.29	SCHIP1	schwannomin interacting protein 1	472	0.82
chr4_15721261_15721412	0.29	BST1	bone marrow stromal cell antigen 1	4385	0.23
chr8_74792715_74792866	0.29	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	1645	0.41
chr6_134803152_134803303	0.29	SGK1	serum/glucocorticoid regulated kinase 1	163977	0.04
chr3_105178540_105178691	0.29	ALCAM	activated leukocyte cell adhesion molecule	53554	0.19
chr4_174198585_174198817	0.28	ENSG00000221296	.	9390	0.17
chr3_124500151_124500305	0.28	ITGB5-AS1	ITGB5 antisense RNA 1	226	0.93
chr15_94850174_94850340	0.28	MCTP2	multiple C2 domains, transmembrane 2	8762	0.33
chr2_102423827_102423978	0.28	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	10176	0.28
chr2_65309092_65309434	0.28	RAB1A	RAB1A, member RAS oncogene family	24261	0.15
chr9_137348457_137348644	0.28	RXRA	retinoid X receptor, alpha	50122	0.15
chr1_11901364_11901515	0.28	NPPA-AS1	NPPA antisense RNA 1	365	0.78
chr3_10215716_10215867	0.27	IRAK2	interleukin-1 receptor-associated kinase 2	9242	0.12
chr1_199147885_199148036	0.27	ENSG00000239006	.	18352	0.3
chr7_6183718_6183869	0.27	USP42	ubiquitin specific peptidase 42	27682	0.11
chr8_66761852_66762003	0.27	PDE7A	phosphodiesterase 7A	7740	0.3
chr17_19206898_19207138	0.27	EPN2-AS1	EPN2 antisense RNA 1	2556	0.18
chr12_108958034_108958185	0.27	ISCU	iron-sulfur cluster assembly enzyme	1723	0.27
chr2_38762873_38763024	0.27	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	34030	0.18
chrX_18665752_18666019	0.27	RS1	retinoschisin 1	24344	0.19
chr20_45934513_45934664	0.26	ENSG00000265532	.	2538	0.2
chr1_161053172_161053323	0.26	RP11-544M22.8		1008	0.29
chr16_86817580_86817731	0.26	FOXL1	forkhead box L1	205540	0.02
chr9_139117528_139117679	0.26	QSOX2	quiescin Q6 sulfhydryl oxidase 2	880	0.58
chr10_121580538_121580689	0.26	INPP5F	inositol polyphosphate-5-phosphatase F	2385	0.32
chr10_134826309_134826460	0.25	GPR123	G protein-coupled receptor 123	58049	0.11
chr7_12588835_12588986	0.25	SCIN	scinderin	21402	0.21
chr13_29156883_29157128	0.25	POMP	proteasome maturation protein	76236	0.1
chr9_114288073_114288445	0.25	ZNF483	zinc finger protein 483	746	0.65
chr14_68608308_68608459	0.25	ENSG00000244677	.	8242	0.23
chr16_70456809_70457112	0.25	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	16031	0.11
chr1_48709961_48710211	0.24	RP5-1024N4.4		14853	0.22
chr9_95895847_95895998	0.24	NINJ1	ninjurin 1	648	0.7
chr9_91390340_91390723	0.24	ENSG00000265873	.	29711	0.24
chr7_26726297_26726654	0.24	C7orf71	chromosome 7 open reading frame 71	48985	0.17
chr19_32837185_32838232	0.24	ZNF507	zinc finger protein 507	1083	0.51
chr1_186445670_186446022	0.24	PDC	phosducin	15592	0.19
chr17_7369936_7370087	0.24	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)	11098	0.06
chr5_134726191_134726464	0.24	H2AFY	H2A histone family, member Y	8574	0.16
chr15_43531002_43531179	0.24	ENSG00000202211	.	8788	0.13
chr8_126374976_126375409	0.24	RP11-550A5.2		11534	0.24
chr12_66429713_66429864	0.24	ENSG00000251857	.	30213	0.17
chr19_996464_996712	0.24	AC004528.1	Uncharacterized protein	3013	0.1
chr8_65490045_65490217	0.23	RP11-21C4.1		311	0.91
chr1_28099274_28099549	0.23	STX12	syntaxin 12	283	0.78
chr6_11207713_11207934	0.23	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	25068	0.18
chr10_120291049_120291200	0.23	ENSG00000266281	.	14482	0.25
chr10_35776302_35776593	0.23	GJD4	gap junction protein, delta 4, 40.1kDa	117891	0.05
chr3_37366423_37366574	0.23	ENSG00000222208	.	16642	0.18
chr2_45464381_45464651	0.23	SIX2	SIX homeobox 2	227947	0.02
chr11_70270544_70270893	0.23	CTTN	cortactin	4118	0.18
chr5_172222413_172222569	0.23	ENSG00000206741	.	15394	0.14
chr1_205216416_205216567	0.23	TMCC2	transmembrane and coiled-coil domain family 2	743	0.63
chr7_138914973_138915166	0.22	UBN2	ubinuclein 2	33	0.98
chr15_58653715_58653866	0.22	LIPC	lipase, hepatic	48978	0.15
chr9_135115291_135115736	0.22	ENSG00000221105	.	25251	0.2
chr6_41680623_41680774	0.22	TFEB	transcription factor EB	7020	0.13
chr3_70903414_70903565	0.22	ENSG00000221382	.	24454	0.23
chr19_35849271_35849508	0.22	FFAR3	free fatty acid receptor 3	27	0.95
chr19_8454744_8454908	0.22	RAB11B	RAB11B, member RAS oncogene family	39	0.64
chr20_62580456_62580607	0.22	UCKL1	uridine-cytidine kinase 1-like 1	1948	0.13
chr21_40386888_40387293	0.21	ENSG00000272015	.	120381	0.05
chr19_11402892_11403043	0.21	TSPAN16	tetraspanin 16	3857	0.12
chr5_169918557_169918708	0.21	CTB-147C13.1		5221	0.24
chr4_139156572_139156855	0.21	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	6790	0.31
chr4_8263775_8264072	0.21	HTRA3	HtrA serine peptidase 3	7569	0.22
chr3_99679872_99680023	0.21	ENSG00000264897	.	3295	0.35
chr12_54623516_54623843	0.21	ENSG00000265371	.	1581	0.23
chr9_78990142_78990293	0.21	RFK	riboflavin kinase	18831	0.24
chr4_78783004_78783324	0.21	MRPL1	mitochondrial ribosomal protein L1	510	0.86
chr4_157114740_157114891	0.21	ENSG00000221189	.	102983	0.08
chr10_50452094_50452371	0.21	C10orf71-AS1	C10orf71 antisense RNA 1	54593	0.1
chr20_35110278_35110568	0.21	DLGAP4	discs, large (Drosophila) homolog-associated protein 4	20273	0.17
chr12_62861008_62861159	0.21	MON2	MON2 homolog (S. cerevisiae)	454	0.83
chr11_116766141_116766351	0.21	SIK3-IT1	SIK3 intronic transcript 1 (non-protein coding)	4809	0.17
chr8_26465978_26466617	0.20	DPYSL2	dihydropyrimidinase-like 2	30376	0.22
chr6_166879262_166879723	0.20	RPS6KA2-IT1	RPS6KA2 intronic transcript 1 (non-protein coding)	621	0.74
chr4_8430147_8430298	0.20	ACOX3	acyl-CoA oxidase 3, pristanoyl	9	0.98
chr1_152005862_152006666	0.20	S100A11	S100 calcium binding protein A11	3247	0.19
chr12_54656131_54656480	0.20	RP11-968A15.2		94	0.92
chr18_60770372_60770523	0.20	RP11-299P2.1		48106	0.16
chr5_148130748_148130917	0.20	ADRB2	adrenoceptor beta 2, surface	75324	0.1
chr5_82771804_82772197	0.20	VCAN	versican	4256	0.33
chr9_124091436_124091643	0.20	GSN	gelsolin	2679	0.21
chr17_34115756_34115930	0.20	MMP28	matrix metallopeptidase 28	6868	0.1
chr5_64331605_64331756	0.20	ENSG00000207439	.	87516	0.1
chr12_124997656_124997821	0.20	NCOR2	nuclear receptor corepressor 2	5102	0.34
chr17_60970180_60970441	0.20	ENSG00000207552	.	51266	0.14
chr1_151254019_151254394	0.20	ZNF687	zinc finger protein 687	112	0.61
chr5_126111660_126112314	0.20	LMNB1	lamin B1	853	0.67
chr6_15463967_15464118	0.20	JARID2	jumonji, AT rich interactive domain 2	62953	0.13
chr13_113664073_113664237	0.20	RP11-120K24.5		170	0.9
chr6_21925832_21925983	0.20	ENSG00000222515	.	159866	0.04
chr19_18491287_18491451	0.20	GDF15	growth differentiation factor 15	1611	0.2
chr16_58535345_58535501	0.20	NDRG4	NDRG family member 4	16	0.97
chr12_27939071_27939324	0.20	RP11-860B13.1		5197	0.13
chrY_2576678_2576907	0.20	ENSG00000251841	.	75998	0.11
chr7_993508_993659	0.19	ADAP1	ArfGAP with dual PH domains 1	750	0.56
chr13_72430784_72430935	0.19	DACH1	dachshund homolog 1 (Drosophila)	10048	0.32
chr9_139117754_139118099	0.19	QSOX2	quiescin Q6 sulfhydryl oxidase 2	1203	0.46
chr2_102093131_102093315	0.19	RFX8	RFX family member 8, lacking RFX DNA binding domain	2058	0.43
chr12_94625674_94625825	0.19	PLXNC1	plexin C1	22545	0.17
chr17_53573843_53573994	0.19	ENSG00000200107	.	55253	0.15
chr5_7803203_7803354	0.19	C5orf49	chromosome 5 open reading frame 49	47986	0.13
chrX_110339162_110339436	0.19	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	289	0.95
chr8_41625601_41625752	0.19	ANK1	ankyrin 1, erythrocytic	29464	0.15
chr1_151508284_151508566	0.19	TUFT1	tuftelin 1	4356	0.12
chr5_177900691_177901194	0.19	CTB-26E19.1		30847	0.19
chr3_171592714_171592972	0.19	TMEM212-IT1	TMEM212 intronic transcript 1 (non-protein coding)	19383	0.19
chr7_132217204_132217355	0.19	PLXNA4	plexin A4	43950	0.19
chr13_107137040_107137296	0.19	EFNB2	ephrin-B2	50294	0.17
chr1_223724894_223725187	0.19	CAPN8	calpain 8	660	0.81
chr8_101348735_101348886	0.18	RNF19A	ring finger protein 19A, RBR E3 ubiquitin protein ligase	378	0.89
chr13_80444406_80444557	0.18	NDFIP2	Nedd4 family interacting protein 2	388893	0.01
chr6_113075862_113076013	0.18	ENSG00000201386	.	216758	0.02
chr15_52138768_52139605	0.18	TMOD3	tropomodulin 3 (ubiquitous)	15849	0.15
chr17_9273783_9274123	0.18	AC087501.1		81561	0.08
chr3_32451109_32451284	0.18	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	17665	0.23
chr12_89511566_89511717	0.18	ENSG00000238302	.	164421	0.04
chr7_5258466_5258734	0.18	WIPI2	WD repeat domain, phosphoinositide interacting 2	4700	0.2
chr7_20341021_20341275	0.18	ITGB8	integrin, beta 8	29177	0.17
chr17_57971307_57971993	0.18	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	1050	0.37
chr9_111034278_111034617	0.18	ENSG00000222512	.	86762	0.11
chr1_43941761_43941966	0.18	HYI	hydroxypyruvate isomerase (putative)	22203	0.12
chr6_34992306_34992644	0.18	TCP11	t-complex 11, testis-specific	96347	0.07
chr3_30668319_30669005	0.17	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	20569	0.26
chr3_172345425_172345576	0.17	AC007919.2	HCG1787166; PRO1163; Uncharacterized protein	15983	0.19
chr9_134516940_134517091	0.17	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	15680	0.22
chr18_33613590_33613806	0.17	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	2885	0.3
chr2_39721987_39722138	0.17	AC007246.3		19225	0.22
chr2_233367753_233368028	0.17	ECEL1	endothelin converting enzyme-like 1	15352	0.1
chr9_139810950_139811101	0.17	RP11-229P13.25		21415	0.06
chr10_44506456_44506924	0.17	ENSG00000238957	.	23298	0.27

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.2	GO:0018101	protein citrullination(GO:0018101)
0.0	0.3	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.3	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.3	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.4	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0010523	negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.2	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.2	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0072191	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0005638	lamin filament(GO:0005638)
0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.1	GO:0032449	CBM complex(GO:0032449)
0.1	GO:0070552	BRISC complex(GO:0070552)
0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.1	GO:0042827	platelet dense granule(GO:0042827)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.3	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.5	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.3	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)