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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ATF7

Z-value: 0.90

Motif logo

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Transcription factors associated with ATF7

Gene Symbol Gene ID Gene Info
ATF7
ENSG00000170653.14 activating transcription factor 7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_53964156_53964307ATF7305740.1091630.742.2e-02Click!
chr12_53989142_53989293ATF755880.1680890.742.3e-02Click!
chr12_54017496_54017647ATF721840.2267200.742.4e-02Click!
chr12_53969438_53969764ATF7252040.1211450.722.9e-02Click!
chr12_53969924_53970134ATF7247760.1220800.713.2e-02Click!

Activity of the ATF7 motif across conditions

Conditions sorted by the z-value of the ATF7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_141015090_141015375 0.64 RP11-392B6.1
33937
 0.2
chr6_80714655_80715350 0.61 TTK
 TTK protein kinase
 451
 0.88
chr5_14264414_14265476 0.60 TRIO
 trio Rho guanine nucleotide exchange factor
 26141
 0.27
chr1_56981894_56982239 0.59 PPAP2B
 phosphatidic acid phosphatase type 2B
 63175
 0.14
chr12_133022629_133022780 0.57 MUC8
 mucin 8
 28022
 0.17
chr2_8552253_8552511 0.57 AC011747.7
263514
 0.02
chr5_73730230_73730381 0.53 ENSG00000244326
 .
 116494
 0.06
chr15_40636361_40636512 0.53 C15orf52
 chromosome 15 open reading frame 52
 3268
 0.1
chr11_12695755_12695947 0.52 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 118
 0.98
chr6_64516560_64517136 0.52 RP11-59D5__B.2
119
 0.98
chr6_14477462_14477818 0.51 ENSG00000206960
 .
 169126
 0.04
chr17_65505786_65506259 0.51 CTD-2653B5.1
14575
 0.17
chr21_44937001_44937451 0.50 SIK1
 salt-inducible kinase 1
 90218
 0.08
chr16_31141784_31142119 0.50 RP11-388M20.2
803
 0.33
chr12_8043408_8043946 0.47 SLC2A14
 solute carrier family 2 (facilitated glucose transporter), member 14
 67
 0.95
chr6_2449367_2449525 0.47 ENSG00000266252
 .
 39577
 0.21
chr1_181056660_181057120 0.46 IER5
 immediate early response 5
 748
 0.71
chr4_74575921_74576072 0.44 IL8
 interleukin 8
 30227
 0.19
chr5_179453537_179453707 0.44 ENSG00000198995
 .
 11225
 0.19
chr14_75655646_75655840 0.44 TMED10
 transmembrane emp24-like trafficking protein 10 (yeast)
 12409
 0.15
chr7_100782348_100782499 0.44 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 12044
 0.1
chr10_6959147_6959298 0.42 PRKCQ
 protein kinase C, theta
 336959
 0.01
chr1_17630639_17630914 0.42 PADI4
 peptidyl arginine deiminase, type IV
 3914
 0.2
chr9_130912677_130912874 0.41 LCN2
 lipocalin 2
 978
 0.34
chr1_22380057_22380208 0.40 CDC42
 cell division cycle 42
 342
 0.82
chr22_44569121_44569281 0.39 PARVG
 parvin, gamma
 365
 0.92
chr8_62625004_62625155 0.39 ASPH
 aspartate beta-hydroxylase
 2005
 0.33
chr11_65256298_65256486 0.38 AP000769.1
 Uncharacterized protein
 33664
 0.08
chr4_153913148_153913299 0.37 FHDC1
 FH2 domain containing 1
 49088
 0.16
chr8_61896258_61896409 0.36 CLVS1
 clavesin 1
 73384
 0.12
chr17_25773754_25774039 0.36 KSR1
 kinase suppressor of ras 1
 9774
 0.19
chr2_28114153_28114304 0.36 RBKS
 ribokinase
 263
 0.74
chr15_49336349_49337349 0.36 SECISBP2L
 SECIS binding protein 2-like
 1781
 0.28
chr6_18403082_18403233 0.36 ENSG00000238458
 .
 874
 0.65
chr17_55446479_55446630 0.36 ENSG00000263902
 .
 43008
 0.17
chr17_42423914_42424082 0.36 GRN
 granulin
 1325
 0.25
chr3_99721724_99721891 0.36 ENSG00000264897
 .
 38565
 0.19
chr2_108994281_108994432 0.35 SULT1C4
 sulfotransferase family, cytosolic, 1C, member 4
 112
 0.97
chr9_111578900_111579091 0.35 ACTL7B
 actin-like 7B
 40244
 0.16
chr18_10791557_10791762 0.35 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 11
 0.99
chr17_61723267_61723570 0.35 MAP3K3
 mitogen-activated protein kinase kinase kinase 3
 23348
 0.13
chr12_6187508_6187659 0.35 ENSG00000240533
 .
 17553
 0.21
chr10_11628107_11628334 0.34 USP6NL
 USP6 N-terminal like
 12380
 0.23
chr2_197944933_197945147 0.33 ANKRD44
 ankyrin repeat domain 44
 30528
 0.22
chr17_42978313_42978555 0.33 CCDC103
 coiled-coil domain containing 103
 1292
 0.19
chr13_99234265_99234566 0.32 STK24-AS1
 STK24 antisense RNA 1
 4917
 0.23
chr13_97876107_97876342 0.32 MBNL2
 muscleblind-like splicing regulator 2
 1615
 0.53
chr8_48393092_48393308 0.32 SPIDR
 scaffolding protein involved in DNA repair
 40237
 0.18
chr2_8144515_8144736 0.32 ENSG00000221255
 .
 427653
 0.01
chr18_20840672_20840823 0.31 RP11-17J14.2
429
 0.89
chr20_36797041_36797355 0.31 TGM2
 transglutaminase 2
 2218
 0.32
chr8_49838453_49838744 0.31 SNAI2
 snail family zinc finger 2
 4299
 0.35
chr6_53213778_53213929 0.31 ELOVL5
 ELOVL fatty acid elongase 5
 48
 0.98
chr16_70730831_70731276 0.31 VAC14
 Vac14 homolog (S. cerevisiae)
 1557
 0.31
chr5_102729544_102729916 0.31 C5orf30
 chromosome 5 open reading frame 30
 134605
 0.05
chr7_132095239_132095390 0.30 AC011625.1
58221
 0.15
chr10_103143872_103144023 0.30 ENSG00000239091
 .
 12238
 0.16
chr16_73087544_73087838 0.30 ZFHX3
 zinc finger homeobox 3
 5417
 0.25
chr1_113361578_113361925 0.30 FAM19A3
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
 98552
 0.05
chr4_38822000_38822151 0.30 TLR6
 toll-like receptor 6
 9085
 0.16
chr14_73927648_73927878 0.30 ENSG00000251393
 .
 1366
 0.34
chr12_124983629_124983780 0.30 NCOR2
 nuclear receptor corepressor 2
 3906
 0.36
chr17_18528921_18529072 0.30 CCDC144B
 coiled-coil domain containing 144B (pseudogene)
 75
 0.96
chr11_13238293_13238470 0.30 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 59818
 0.15
chr4_159131101_159131306 0.29 TMEM144
 transmembrane protein 144
 143
 0.96
chr18_22820121_22820315 0.29 ZNF521
 zinc finger protein 521
 8724
 0.3
chr15_91040083_91040234 0.29 CRTC3
 CREB regulated transcription coactivator 3
 32999
 0.15
chr3_159571102_159571298 0.29 SCHIP1
 schwannomin interacting protein 1
 472
 0.82
chr4_15721261_15721412 0.29 BST1
 bone marrow stromal cell antigen 1
 4385
 0.23
chr8_74792715_74792866 0.29 UBE2W
 ubiquitin-conjugating enzyme E2W (putative)
 1645
 0.41
chr6_134803152_134803303 0.29 SGK1
 serum/glucocorticoid regulated kinase 1
 163977
 0.04
chr3_105178540_105178691 0.29 ALCAM
 activated leukocyte cell adhesion molecule
 53554
 0.19
chr4_174198585_174198817 0.28 ENSG00000221296
 .
 9390
 0.17
chr3_124500151_124500305 0.28 ITGB5-AS1
 ITGB5 antisense RNA 1
 226
 0.93
chr15_94850174_94850340 0.28 MCTP2
 multiple C2 domains, transmembrane 2
 8762
 0.33
chr2_102423827_102423978 0.28 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 10176
 0.28
chr2_65309092_65309434 0.28 RAB1A
 RAB1A, member RAS oncogene family
 24261
 0.15
chr9_137348457_137348644 0.28 RXRA
 retinoid X receptor, alpha
 50122
 0.15
chr1_11901364_11901515 0.28 NPPA-AS1
 NPPA antisense RNA 1
 365
 0.78
chr3_10215716_10215867 0.27 IRAK2
 interleukin-1 receptor-associated kinase 2
 9242
 0.12
chr1_199147885_199148036 0.27 ENSG00000239006
 .
 18352
 0.3
chr7_6183718_6183869 0.27 USP42
 ubiquitin specific peptidase 42
 27682
 0.11
chr8_66761852_66762003 0.27 PDE7A
 phosphodiesterase 7A
 7740
 0.3
chr17_19206898_19207138 0.27 EPN2-AS1
 EPN2 antisense RNA 1
 2556
 0.18
chr12_108958034_108958185 0.27 ISCU
 iron-sulfur cluster assembly enzyme
 1723
 0.27
chr2_38762873_38763024 0.27 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 34030
 0.18
chrX_18665752_18666019 0.27 RS1
 retinoschisin 1
 24344
 0.19
chr20_45934513_45934664 0.26 ENSG00000265532
 .
 2538
 0.2
chr1_161053172_161053323 0.26 RP11-544M22.8
1008
 0.29
chr16_86817580_86817731 0.26 FOXL1
 forkhead box L1
 205540
 0.02
chr9_139117528_139117679 0.26 QSOX2
 quiescin Q6 sulfhydryl oxidase 2
 880
 0.58
chr10_121580538_121580689 0.26 INPP5F
 inositol polyphosphate-5-phosphatase F
 2385
 0.32
chr10_134826309_134826460 0.25 GPR123
 G protein-coupled receptor 123
 58049
 0.11
chr7_12588835_12588986 0.25 SCIN
 scinderin
 21402
 0.21
chr13_29156883_29157128 0.25 POMP
 proteasome maturation protein
 76236
 0.1
chr9_114288073_114288445 0.25 ZNF483
 zinc finger protein 483
 746
 0.65
chr14_68608308_68608459 0.25 ENSG00000244677
 .
 8242
 0.23
chr16_70456809_70457112 0.25 ST3GAL2
 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
 16031
 0.11
chr1_48709961_48710211 0.24 RP5-1024N4.4
14853
 0.22
chr9_95895847_95895998 0.24 NINJ1
 ninjurin 1
 648
 0.7
chr9_91390340_91390723 0.24 ENSG00000265873
 .
 29711
 0.24
chr7_26726297_26726654 0.24 C7orf71
 chromosome 7 open reading frame 71
 48985
 0.17
chr19_32837185_32838232 0.24 ZNF507
 zinc finger protein 507
 1083
 0.51
chr1_186445670_186446022 0.24 PDC
 phosducin
 15592
 0.19
chr17_7369936_7370087 0.24 CHRNB1
 cholinergic receptor, nicotinic, beta 1 (muscle)
 11098
 0.06
chr5_134726191_134726464 0.24 H2AFY
 H2A histone family, member Y
 8574
 0.16
chr15_43531002_43531179 0.24 ENSG00000202211
 .
 8788
 0.13
chr8_126374976_126375409 0.24 RP11-550A5.2
11534
 0.24
chr12_66429713_66429864 0.24 ENSG00000251857
 .
 30213
 0.17
chr19_996464_996712 0.24 AC004528.1
 Uncharacterized protein
 3013
 0.1
chr8_65490045_65490217 0.23 RP11-21C4.1
311
 0.91
chr1_28099274_28099549 0.23 STX12
 syntaxin 12
 283
 0.78
chr6_11207713_11207934 0.23 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 25068
 0.18
chr10_120291049_120291200 0.23 ENSG00000266281
 .
 14482
 0.25
chr10_35776302_35776593 0.23 GJD4
 gap junction protein, delta 4, 40.1kDa
 117891
 0.05
chr3_37366423_37366574 0.23 ENSG00000222208
 .
 16642
 0.18
chr2_45464381_45464651 0.23 SIX2
 SIX homeobox 2
 227947
 0.02
chr11_70270544_70270893 0.23 CTTN
 cortactin
 4118
 0.18
chr5_172222413_172222569 0.23 ENSG00000206741
 .
 15394
 0.14
chr1_205216416_205216567 0.23 TMCC2
 transmembrane and coiled-coil domain family 2
 743
 0.63
chr7_138914973_138915166 0.22 UBN2
 ubinuclein 2
 33
 0.98
chr15_58653715_58653866 0.22 LIPC
 lipase, hepatic
 48978
 0.15
chr9_135115291_135115736 0.22 ENSG00000221105
 .
 25251
 0.2
chr6_41680623_41680774 0.22 TFEB
 transcription factor EB
 7020
 0.13
chr3_70903414_70903565 0.22 ENSG00000221382
 .
 24454
 0.23
chr19_35849271_35849508 0.22 FFAR3
 free fatty acid receptor 3
 27
 0.95
chr19_8454744_8454908 0.22 RAB11B
 RAB11B, member RAS oncogene family
 39
 0.64
chr20_62580456_62580607 0.22 UCKL1
 uridine-cytidine kinase 1-like 1
 1948
 0.13
chr21_40386888_40387293 0.21 ENSG00000272015
 .
 120381
 0.05
chr19_11402892_11403043 0.21 TSPAN16
 tetraspanin 16
 3857
 0.12
chr5_169918557_169918708 0.21 CTB-147C13.1
5221
 0.24
chr4_139156572_139156855 0.21 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 6790
 0.31
chr4_8263775_8264072 0.21 HTRA3
 HtrA serine peptidase 3
 7569
 0.22
chr3_99679872_99680023 0.21 ENSG00000264897
 .
 3295
 0.35
chr12_54623516_54623843 0.21 ENSG00000265371
 .
 1581
 0.23
chr9_78990142_78990293 0.21 RFK
 riboflavin kinase
 18831
 0.24
chr4_78783004_78783324 0.21 MRPL1
 mitochondrial ribosomal protein L1
 510
 0.86
chr4_157114740_157114891 0.21 ENSG00000221189
 .
 102983
 0.08
chr10_50452094_50452371 0.21 C10orf71-AS1
 C10orf71 antisense RNA 1
 54593
 0.1
chr20_35110278_35110568 0.21 DLGAP4
 discs, large (Drosophila) homolog-associated protein 4
 20273
 0.17
chr12_62861008_62861159 0.21 MON2
 MON2 homolog (S. cerevisiae)
 454
 0.83
chr11_116766141_116766351 0.21 SIK3-IT1
 SIK3 intronic transcript 1 (non-protein coding)
 4809
 0.17
chr8_26465978_26466617 0.20 DPYSL2
 dihydropyrimidinase-like 2
 30376
 0.22
chr6_166879262_166879723 0.20 RPS6KA2-IT1
 RPS6KA2 intronic transcript 1 (non-protein coding)
 621
 0.74
chr4_8430147_8430298 0.20 ACOX3
 acyl-CoA oxidase 3, pristanoyl
 9
 0.98
chr1_152005862_152006666 0.20 S100A11
 S100 calcium binding protein A11
 3247
 0.19
chr12_54656131_54656480 0.20 RP11-968A15.2
94
 0.92
chr18_60770372_60770523 0.20 RP11-299P2.1
48106
 0.16
chr5_148130748_148130917 0.20 ADRB2
 adrenoceptor beta 2, surface
 75324
 0.1
chr5_82771804_82772197 0.20 VCAN
 versican
 4256
 0.33
chr9_124091436_124091643 0.20 GSN
 gelsolin
 2679
 0.21
chr17_34115756_34115930 0.20 MMP28
 matrix metallopeptidase 28
 6868
 0.1
chr5_64331605_64331756 0.20 ENSG00000207439
 .
 87516
 0.1
chr12_124997656_124997821 0.20 NCOR2
 nuclear receptor corepressor 2
 5102
 0.34
chr17_60970180_60970441 0.20 ENSG00000207552
 .
 51266
 0.14
chr1_151254019_151254394 0.20 ZNF687
 zinc finger protein 687
 112
 0.61
chr5_126111660_126112314 0.20 LMNB1
 lamin B1
 853
 0.67
chr6_15463967_15464118 0.20 JARID2
 jumonji, AT rich interactive domain 2
 62953
 0.13
chr13_113664073_113664237 0.20 RP11-120K24.5
170
 0.9
chr6_21925832_21925983 0.20 ENSG00000222515
 .
 159866
 0.04
chr19_18491287_18491451 0.20 GDF15
 growth differentiation factor 15
 1611
 0.2
chr16_58535345_58535501 0.20 NDRG4
 NDRG family member 4
 16
 0.97
chr12_27939071_27939324 0.20 RP11-860B13.1
5197
 0.13
chrY_2576678_2576907 0.20 ENSG00000251841
 .
 75998
 0.11
chr7_993508_993659 0.19 ADAP1
 ArfGAP with dual PH domains 1
 750
 0.56
chr13_72430784_72430935 0.19 DACH1
 dachshund homolog 1 (Drosophila)
 10048
 0.32
chr9_139117754_139118099 0.19 QSOX2
 quiescin Q6 sulfhydryl oxidase 2
 1203
 0.46
chr2_102093131_102093315 0.19 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 2058
 0.43
chr12_94625674_94625825 0.19 PLXNC1
 plexin C1
 22545
 0.17
chr17_53573843_53573994 0.19 ENSG00000200107
 .
 55253
 0.15
chr5_7803203_7803354 0.19 C5orf49
 chromosome 5 open reading frame 49
 47986
 0.13
chrX_110339162_110339436 0.19 PAK3
 p21 protein (Cdc42/Rac)-activated kinase 3
 289
 0.95
chr8_41625601_41625752 0.19 ANK1
 ankyrin 1, erythrocytic
 29464
 0.15
chr1_151508284_151508566 0.19 TUFT1
 tuftelin 1
 4356
 0.12
chr5_177900691_177901194 0.19 CTB-26E19.1
30847
 0.19
chr3_171592714_171592972 0.19 TMEM212-IT1
 TMEM212 intronic transcript 1 (non-protein coding)
 19383
 0.19
chr7_132217204_132217355 0.19 PLXNA4
 plexin A4
 43950
 0.19
chr13_107137040_107137296 0.19 EFNB2
 ephrin-B2
 50294
 0.17
chr1_223724894_223725187 0.19 CAPN8
 calpain 8
 660
 0.81
chr8_101348735_101348886 0.18 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
 378
 0.89
chr13_80444406_80444557 0.18 NDFIP2
 Nedd4 family interacting protein 2
 388893
 0.01
chr6_113075862_113076013 0.18 ENSG00000201386
 .
 216758
 0.02
chr15_52138768_52139605 0.18 TMOD3
 tropomodulin 3 (ubiquitous)
 15849
 0.15
chr17_9273783_9274123 0.18 AC087501.1
81561
 0.08
chr3_32451109_32451284 0.18 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 17665
 0.23
chr12_89511566_89511717 0.18 ENSG00000238302
 .
 164421
 0.04
chr7_5258466_5258734 0.18 WIPI2
 WD repeat domain, phosphoinositide interacting 2
 4700
 0.2
chr7_20341021_20341275 0.18 ITGB8
 integrin, beta 8
 29177
 0.17
chr17_57971307_57971993 0.18 RPS6KB1
 ribosomal protein S6 kinase, 70kDa, polypeptide 1
 1050
 0.37
chr9_111034278_111034617 0.18 ENSG00000222512
 .
 86762
 0.11
chr1_43941761_43941966 0.18 HYI
 hydroxypyruvate isomerase (putative)
 22203
 0.12
chr6_34992306_34992644 0.18 TCP11
 t-complex 11, testis-specific
 96347
 0.07
chr3_30668319_30669005 0.17 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 20569
 0.26
chr3_172345425_172345576 0.17 AC007919.2
 HCG1787166; PRO1163; Uncharacterized protein
 15983
 0.19
chr9_134516940_134517091 0.17 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 15680
 0.22
chr18_33613590_33613806 0.17 RPRD1A
 regulation of nuclear pre-mRNA domain containing 1A
 2885
 0.3
chr2_39721987_39722138 0.17 AC007246.3
19225
 0.22
chr2_233367753_233368028 0.17 ECEL1
 endothelin converting enzyme-like 1
 15352
 0.1
chr9_139810950_139811101 0.17 RP11-229P13.25
21415
 0.06
chr10_44506456_44506924 0.17 ENSG00000238957
 .
 23298
 0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101)
0.0 0.3 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.2 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0072191 positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)