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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for BACH2

Z-value: 0.74

Motif logo

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
BACH2
ENSG00000112182.10 BTB domain and CNC homolog 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_90981476_90981674BACH2248860.218364-0.901.0e-03Click!
chr6_90981736_90981993BACH2245970.218974-0.891.3e-03Click!
chr6_90982113_90982279BACH2242650.219669-0.862.6e-03Click!
chr6_90984432_90984583BACH2219540.224353-0.835.1e-03Click!
chr6_90951264_90951456BACH2551010.146848-0.826.5e-03Click!

Activity of the BACH2 motif across conditions

Conditions sorted by the z-value of the BACH2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_18539696_18539847 0.49 XXbac-B476C20.9
20792
 0.13
chr2_231481752_231482027 0.42 ENSG00000199791
 .
 30053
 0.17
chr1_232845212_232845363 0.42 ENSG00000238382
 .
 9337
 0.28
chr2_128155940_128156196 0.39 MAP3K2
 mitogen-activated protein kinase kinase kinase 2
 10027
 0.16
chr2_110316196_110316465 0.38 AC011753.5
46945
 0.13
chr4_8192745_8193409 0.38 SH3TC1
 SH3 domain and tetratricopeptide repeats 1
 8014
 0.22
chr15_52393088_52393274 0.36 CTD-2184D3.5
461
 0.77
chr2_43303091_43303242 0.35 ENSG00000207087
 .
 15466
 0.28
chr19_39224351_39224502 0.35 CAPN12
 calpain 12
 1619
 0.22
chr12_66089171_66089322 0.34 HMGA2
 high mobility group AT-hook 2
 128665
 0.05
chr12_6388900_6389082 0.34 PLEKHG6
 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
 30611
 0.12
chr8_145993953_145994104 0.34 ZNF34
 zinc finger protein 34
 11639
 0.11
chr2_26235492_26235765 0.33 AC013449.1
 Uncharacterized protein
 15853
 0.16
chr8_102038362_102038931 0.33 ENSG00000252736
 .
 63375
 0.1
chr4_144276820_144277057 0.33 ENSG00000265623
 .
 12325
 0.2
chr2_225544034_225544185 0.33 CUL3
 cullin 3
 93999
 0.09
chr17_40561664_40561962 0.33 ENSG00000221020
 .
 10786
 0.11
chr1_244437634_244437902 0.32 C1orf100
 chromosome 1 open reading frame 100
 78169
 0.1
chr6_41680801_41681561 0.32 RP11-298J23.5
6953
 0.13
chr12_56120404_56120555 0.32 CD63
 CD63 molecule
 364
 0.7
chr4_10097090_10097875 0.31 ENSG00000264931
 .
 17166
 0.14
chr11_58395317_58395468 0.30 CNTF
 ciliary neurotrophic factor
 5246
 0.17
chr3_112500584_112500735 0.30 ENSG00000242770
 .
 20666
 0.22
chr17_48128276_48128773 0.29 ITGA3
 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
 4815
 0.16
chr19_16175455_16175640 0.29 TPM4
 tropomyosin 4
 2284
 0.28
chr15_74688962_74689487 0.28 CYP11A1
 cytochrome P450, family 11, subfamily A, polypeptide 1
 29143
 0.11
chr17_75118639_75118790 0.28 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 5241
 0.22
chr13_114524672_114524969 0.27 GAS6-AS1
 GAS6 antisense RNA 1
 6217
 0.22
chr1_31229795_31230155 0.27 LAPTM5
 lysosomal protein transmembrane 5
 692
 0.65
chr14_59827605_59828209 0.27 ENSG00000252869
 .
 38834
 0.18
chr3_119854481_119854726 0.27 ENSG00000244139
 .
 13847
 0.18
chr14_62052476_62052660 0.27 RP11-47I22.3
 Uncharacterized protein
 15254
 0.21
chr15_74281262_74281725 0.27 STOML1
 stomatin (EPB72)-like 1
 2682
 0.22
chr5_168521975_168522126 0.26 CTB-174D11.1
64607
 0.13
chr13_33836245_33836396 0.26 ENSG00000236581
 .
 9196
 0.23
chr1_1240872_1241150 0.26 ACAP3
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
 2258
 0.11
chr14_59895317_59895579 0.26 ENSG00000252869
 .
 28707
 0.16
chr9_124044825_124044976 0.26 RP11-477J21.6
108
 0.95
chr1_10519294_10519577 0.26 RP5-1113E3.3
823
 0.46
chr16_70780334_70780534 0.26 RP11-394B2.6
526
 0.69
chr5_148865258_148865409 0.25 CSNK1A1
 casein kinase 1, alpha 1
 27387
 0.14
chr8_41655772_41655923 0.25 ANK1
 ankyrin 1, erythrocytic
 707
 0.67
chr9_130326042_130326221 0.25 FAM129B
 family with sequence similarity 129, member B
 5236
 0.19
chr17_29907812_29907963 0.25 ENSG00000199187
 .
 5457
 0.13
chr5_14038564_14038715 0.25 DNAH5
 dynein, axonemal, heavy chain 5
 93987
 0.09
chr1_10961180_10961385 0.25 C1orf127
 chromosome 1 open reading frame 127
 46645
 0.12
chr5_65107256_65107407 0.25 NLN
 neurolysin (metallopeptidase M3 family)
 23141
 0.22
chr1_10891158_10891309 0.25 CASZ1
 castor zinc finger 1
 34526
 0.18
chr9_127457900_127458051 0.24 ENSG00000207737
 .
 1986
 0.26
chr1_59491106_59491398 0.24 JUN
 jun proto-oncogene
 241467
 0.02
chr6_10633412_10633876 0.24 GCNT6
 glucosaminyl (N-acetyl) transferase 6
 349
 0.86
chr8_101774241_101774392 0.24 ENSG00000202001
 .
 6893
 0.17
chr1_202557788_202557939 0.23 RP11-569A11.1
15533
 0.2
chr15_79621555_79621707 0.23 ENSG00000266543
 .
 9441
 0.2
chr21_43084452_43084603 0.23 LINC00112
 long intergenic non-protein coding RNA 112
 52069
 0.12
chr22_37669382_37669767 0.23 CYTH4
 cytohesin 4
 8494
 0.16
chr11_65259042_65259542 0.23 SCYL1
 SCY1-like 1 (S. cerevisiae)
 33256
 0.08
chr7_137457647_137457798 0.23 DGKI
 diacylglycerol kinase, iota
 73560
 0.12
chr6_100731277_100731428 0.23 RP1-121G13.2
143642
 0.05
chr6_43090954_43091105 0.23 PTK7
 protein tyrosine kinase 7
 7300
 0.13
chr22_27288381_27288532 0.23 ENSG00000200443
 .
 143394
 0.05
chr5_149401334_149401630 0.23 ENSG00000238369
 .
 7533
 0.14
chr13_109567579_109568598 0.23 MYO16
 myosin XVI
 29571
 0.26
chr1_95163966_95164117 0.23 ENSG00000263526
 .
 47415
 0.17
chr1_214731522_214731884 0.22 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 7137
 0.28
chr8_143757384_143757535 0.22 PSCA
 prostate stem cell antigen
 4415
 0.13
chr9_132007671_132007822 0.22 ENSG00000220992
 .
 14750
 0.17
chr22_47330919_47331070 0.22 ENSG00000221672
 .
 87191
 0.09
chr18_46463843_46464371 0.22 SMAD7
 SMAD family member 7
 10768
 0.25
chr2_153271980_153272131 0.22 FMNL2
 formin-like 2
 80304
 0.11
chr15_40577810_40578209 0.22 ANKRD63
 ankyrin repeat domain 63
 3222
 0.12
chr1_154701622_154701930 0.22 ADAR
 adenosine deaminase, RNA-specific
 101302
 0.05
chr4_148698718_148698869 0.22 ENSG00000264274
 .
 4953
 0.21
chr3_48603652_48603803 0.22 UCN2
 urocortin 2
 2521
 0.14
chr5_52105602_52106304 0.21 CTD-2288O8.1
22093
 0.18
chr7_24826656_24826935 0.21 DFNA5
 deafness, autosomal dominant 5
 17551
 0.26
chr17_2786695_2787071 0.21 CTD-3060P21.1
82306
 0.07
chr2_238410967_238411392 0.21 MLPH
 melanophilin
 15260
 0.18
chr11_9010825_9011174 0.21 NRIP3
 nuclear receptor interacting protein 3
 3696
 0.14
chr2_60743198_60743767 0.21 AC009970.1
20661
 0.21
chr1_27325551_27325702 0.21 TRNP1
 TMF1-regulated nuclear protein 1
 4816
 0.17
chr17_28111866_28112121 0.21 ENSG00000252657
 .
 7356
 0.17
chr5_153003729_153003880 0.21 ENSG00000242976
 .
 131138
 0.05
chr19_49071957_49072108 0.21 SULT2B1
 sulfotransferase family, cytosolic, 2B, member 1
 6765
 0.11
chr21_33836630_33836895 0.21 EVA1C
 eva-1 homolog C (C. elegans)
 36120
 0.13
chr21_38936455_38936763 0.21 AP001421.1
 Uncharacterized protein
 47869
 0.16
chr21_38711029_38711180 0.21 AP001437.1
27130
 0.16
chr6_107009204_107009507 0.21 AIM1
 absent in melanoma 1
 20326
 0.18
chr16_57841238_57841389 0.21 CTD-2600O9.1
 uncharacterized protein LOC388282
 3236
 0.18
chr20_3824293_3824586 0.21 MAVS
 mitochondrial antiviral signaling protein
 3048
 0.18
chr2_169429731_169430128 0.21 ENSG00000265694
 .
 9524
 0.23
chr5_176040795_176040946 0.21 GPRIN1
 G protein regulated inducer of neurite outgrowth 1
 3736
 0.14
chr5_106767835_106767986 0.21 EFNA5
 ephrin-A5
 238418
 0.02
chr5_159609192_159609343 0.21 FABP6
 fatty acid binding protein 6, ileal
 5107
 0.2
chr6_158902774_158902925 0.20 ENSG00000243373
 .
 44020
 0.14
chr11_130903385_130903536 0.20 ENSG00000242673
 .
 29136
 0.23
chr14_75355002_75355210 0.20 DLST
 dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
 6447
 0.15
chr5_123932447_123932800 0.20 RP11-436H11.2
131901
 0.05
chr20_52407741_52407914 0.20 ENSG00000238468
 .
 122530
 0.05
chr16_10678700_10678851 0.20 EMP2
 epithelial membrane protein 2
 4220
 0.21
chr5_14268148_14268359 0.20 TRIO
 trio Rho guanine nucleotide exchange factor
 22833
 0.28
chr19_13163011_13163312 0.20 AC007787.2
19027
 0.09
chr15_36720781_36720932 0.20 C15orf41
 chromosome 15 open reading frame 41
 150956
 0.05
chr3_11642284_11642435 0.20 VGLL4
 vestigial like 4 (Drosophila)
 3696
 0.24
chr12_132356722_132356873 0.20 ULK1
 unc-51 like autophagy activating kinase 1
 22399
 0.14
chr15_71881190_71881341 0.20 THSD4
 thrombospondin, type I, domain containing 4
 41690
 0.19
chr16_11295567_11296301 0.20 RMI2
 RecQ mediated genome instability 2
 47572
 0.08
chr3_71651118_71651323 0.20 FOXP1
 forkhead box P1
 18080
 0.2
chr5_135347184_135347335 0.20 TGFBI
 transforming growth factor, beta-induced, 68kDa
 17325
 0.2
chr6_56526637_56526788 0.20 DST
 dystonin
 18918
 0.28
chr12_24893513_24893767 0.19 ENSG00000240481
 .
 33918
 0.21
chr12_124997368_124997619 0.19 NCOR2
 nuclear receptor corepressor 2
 5347
 0.33
chr15_99664062_99664434 0.19 RP11-6O2.4
7763
 0.14
chr10_29273394_29273655 0.19 ENSG00000199402
 .
 110088
 0.07
chr14_103603313_103603536 0.19 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 4339
 0.2
chr11_104005552_104005703 0.19 PDGFD
 platelet derived growth factor D
 29208
 0.23
chr7_55260410_55260561 0.19 EGFR-AS1
 EGFR antisense RNA 1
 3858
 0.34
chr16_14404359_14404586 0.19 ENSG00000199130
 .
 1330
 0.44
chr5_72969116_72969415 0.19 ARHGEF28
 Rho guanine nucleotide exchange factor (GEF) 28
 11392
 0.24
chr10_70982539_70983066 0.19 HKDC1
 hexokinase domain containing 1
 2743
 0.22
chr2_110859211_110859419 0.19 MALL
 mal, T-cell differentiation protein-like
 14284
 0.15
chr9_84174156_84174449 0.19 TLE1
 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
 54135
 0.17
chr5_148513977_148514128 0.19 ABLIM3
 actin binding LIM protein family, member 3
 6994
 0.18
chr17_47533894_47534339 0.19 NGFR
 nerve growth factor receptor
 38539
 0.1
chr18_21978734_21978885 0.19 OSBPL1A
 oxysterol binding protein-like 1A
 986
 0.48
chr1_155223556_155224415 0.19 FAM189B
 family with sequence similarity 189, member B
 714
 0.38
chr18_10035524_10035675 0.19 ENSG00000263630
 .
 30405
 0.21
chr15_67467838_67468111 0.19 SMAD3
 SMAD family member 3
 9105
 0.22
chr19_4794956_4795151 0.19 AC005523.2
514
 0.66
chr16_88298714_88299235 0.19 ZNF469
 zinc finger protein 469
 194905
 0.02
chr20_34673805_34674098 0.19 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
 5475
 0.21
chr9_127023759_127023910 0.19 NEK6
 NIMA-related kinase 6
 82
 0.83
chr7_91476158_91476309 0.19 MTERF
 mitochondrial transcription termination factor
 33744
 0.22
chr19_16174815_16174966 0.19 TPM4
 tropomyosin 4
 2941
 0.24
chr18_59658543_59658754 0.18 RNF152
 ring finger protein 152
 97184
 0.08
chr12_68958912_68959888 0.18 RAP1B
 RAP1B, member of RAS oncogene family
 45219
 0.16
chr2_29850371_29850522 0.18 ENSG00000242699
 .
 53743
 0.16
chr22_41961672_41961960 0.18 CSDC2
 cold shock domain containing C2, RNA binding
 5049
 0.14
chr1_200746157_200746308 0.18 CAMSAP2
 calmodulin regulated spectrin-associated protein family, member 2
 37325
 0.18
chr18_55758646_55758797 0.18 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 44263
 0.17
chr9_113515310_113515461 0.18 MUSK
 muscle, skeletal, receptor tyrosine kinase
 22242
 0.25
chr5_141742469_141742735 0.18 AC005592.2
9494
 0.25
chr7_155088256_155088792 0.18 INSIG1
 insulin induced gene 1
 962
 0.62
chr15_52369332_52369483 0.18 CTD-2184D3.5
23313
 0.13
chr22_47226754_47226905 0.18 ENSG00000221672
 .
 16974
 0.22
chr12_112741045_112741373 0.18 ENSG00000201428
 .
 36328
 0.15
chr11_93470751_93471427 0.18 ENSG00000210825
 .
 2687
 0.08
chr2_43152306_43152732 0.18 HAAO
 3-hydroxyanthranilate 3,4-dioxygenase
 132787
 0.05
chr4_148752956_148753135 0.18 ENSG00000240014
 .
 22968
 0.19
chr19_18681741_18681892 0.18 UBA52
 ubiquitin A-52 residue ribosomal protein fusion product 1
 724
 0.4
chr19_49071674_49071825 0.18 SULT2B1
 sulfotransferase family, cytosolic, 2B, member 1
 7048
 0.11
chr1_114665539_114665690 0.18 SYT6
 synaptotagmin VI
 29448
 0.22
chr19_38794620_38794771 0.18 C19orf33
 chromosome 19 open reading frame 33
 106
 0.92
chr17_42622509_42622660 0.18 FZD2
 frizzled family receptor 2
 12341
 0.18
chr9_16204302_16204453 0.18 C9orf92
 chromosome 9 open reading frame 92
 11520
 0.31
chr9_135506787_135506938 0.18 DDX31
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
 32025
 0.15
chr10_6261359_6261510 0.18 PFKFB3
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
 1933
 0.3
chr1_26610395_26611734 0.18 SH3BGRL3
 SH3 domain binding glutamic acid-rich protein like 3
 4451
 0.13
chr6_130023402_130023553 0.18 ARHGAP18
 Rho GTPase activating protein 18
 7893
 0.27
chr2_39869646_39869797 0.18 TMEM178A
 transmembrane protein 178A
 23338
 0.24
chr9_97682173_97682324 0.18 RP11-54O15.3
14980
 0.17
chr2_25570321_25570568 0.17 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 4985
 0.24
chr18_74452398_74452589 0.17 ENSG00000252097
 .
 60237
 0.13
chr18_8122134_8122285 0.17 PTPRM
 protein tyrosine phosphatase, receptor type, M
 8640
 0.24
chr19_576051_576313 0.17 BSG
 basigin (Ok blood group)
 961
 0.34
chr2_235586595_235586746 0.17 ARL4C
 ADP-ribosylation factor-like 4C
 180973
 0.03
chr16_9141478_9141964 0.17 C16orf72
 chromosome 16 open reading frame 72
 43784
 0.12
chr22_46402793_46403252 0.17 WNT7B
 wingless-type MMTV integration site family, member 7B
 30013
 0.1
chr20_25290765_25291165 0.17 ABHD12
 abhydrolase domain containing 12
 831
 0.64
chr5_10555649_10555800 0.17 ANKRD33B
 ankyrin repeat domain 33B
 8856
 0.2
chr8_37373070_37373278 0.17 RP11-150O12.6
1365
 0.56
chr8_71125713_71126274 0.17 NCOA2
 nuclear receptor coactivator 2
 31617
 0.21
chr15_59460757_59460908 0.17 ENSG00000253030
 .
 2629
 0.17
chr5_109201537_109201688 0.17 AC011366.3
 Uncharacterized protein
 17271
 0.29
chr18_9743354_9743731 0.17 RAB31
 RAB31, member RAS oncogene family
 35380
 0.17
chr2_20696028_20696179 0.17 ENSG00000200829
 .
 15498
 0.21
chr4_53791904_53792055 0.17 RP11-752D24.2
19837
 0.23
chr4_48175111_48175594 0.17 ENSG00000202014
 .
 19901
 0.18
chr11_69069206_69069429 0.17 MYEOV
 myeloma overexpressed
 7692
 0.29
chr17_78801730_78801881 0.17 RP11-28G8.1
22373
 0.2
chr1_17525565_17525716 0.17 PADI1
 peptidyl arginine deiminase, type I
 5981
 0.19
chr2_206599303_206599570 0.17 AC007362.3
29241
 0.21
chr16_4994791_4994942 0.17 ENSG00000200980
 .
 7026
 0.15
chr1_41568152_41568303 0.17 SCMH1
 sex comb on midleg homolog 1 (Drosophila)
 57378
 0.13
chr5_14165682_14165833 0.17 TRIO
 trio Rho guanine nucleotide exchange factor
 18150
 0.3
chr2_20696298_20696449 0.17 ENSG00000200829
 .
 15768
 0.21
chr22_44756801_44756952 0.17 RP1-32I10.10
 Uncharacterized protein
 4555
 0.29
chr17_60780537_60780688 0.17 RP11-156L14.1
2955
 0.22
chr12_52074390_52074541 0.17 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
 5742
 0.28
chr1_222060065_222060216 0.17 ENSG00000200033
 .
 49361
 0.18
chr2_47420449_47420733 0.17 CALM2
 calmodulin 2 (phosphorylase kinase, delta)
 16851
 0.2
chr8_22779071_22779222 0.17 PEBP4
 phosphatidylethanolamine-binding protein 4
 6275
 0.16
chr12_117039449_117039758 0.17 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 25947
 0.23
chr20_19601854_19602005 0.16 ENSG00000216017
 .
 31098
 0.2
chr16_4368044_4368195 0.16 GLIS2
 GLIS family zinc finger 2
 3357
 0.17
chr7_35635806_35635957 0.16 HERPUD2
 HERPUD family member 2
 98295
 0.08
chr4_102077826_102078189 0.16 ENSG00000221265
 .
 173564
 0.03
chr5_14268406_14268609 0.16 TRIO
 trio Rho guanine nucleotide exchange factor
 22579
 0.28
chr12_77425511_77425662 0.16 E2F7
 E2F transcription factor 7
 18940
 0.27
chr3_196001577_196001860 0.16 PCYT1A
 phosphate cytidylyltransferase 1, choline, alpha
 4306
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.2 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0090594 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.1 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.0 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism