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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BATF3

Z-value: 0.27

Motif logo

Transcription factors associated with BATF3

Gene Symbol	Gene ID	Gene Info
BATF3 Ensembl NCBI GeneCards UniProt	ENSG00000123685.4	BATF3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
BATF3	chr1_212911456_212911607	38204	0.119129	0.82	7.1e-03	Click!
BATF3	chr1_212884026_212884300	10836	0.168773	0.55	1.3e-01	Click!
BATF3	chr1_212894826_212895572	21872	0.151734	-0.50	1.7e-01	Click!
BATF3	chr1_212874351_212874643	1170	0.452951	-0.43	2.5e-01	Click!
BATF3	chr1_212901261_212901450	28028	0.140262	0.38	3.1e-01	Click!

Activity of the BATF3 motif across conditions

Conditions sorted by the z-value of the BATF3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_156696862_156697210	0.23	CYFIP2	cytoplasmic FMR1 interacting protein 2	674	0.62
chr2_144280347_144280652	0.22	AC096558.1		42141	0.16
chr4_170581231_170581398	0.16	CLCN3	chloride channel, voltage-sensitive 3	101	0.98
chr9_6915729_6915880	0.16	KDM4C	lysine (K)-specific demethylase 4C	9697	0.24
chr5_177900691_177901194	0.15	CTB-26E19.1		30847	0.19
chr21_18983750_18984027	0.14	BTG3	BTG family, member 3	1274	0.5
chr17_1305657_1305808	0.14	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	2060	0.29
chr6_158306516_158306953	0.13	RP3-403L10.3		7084	0.18
chr13_30747324_30747475	0.13	ENSG00000266816	.	33437	0.22
chr4_185069136_185069287	0.13	ENPP6	ectonucleotide pyrophosphatase/phosphodiesterase 6	69903	0.11
chr3_45911190_45911341	0.13	CCR9	chemokine (C-C motif) receptor 9	16731	0.15
chr1_186798987_186799161	0.13	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	952	0.72
chrX_129318276_129318427	0.12	RAB33A	RAB33A, member RAS oncogene family	12728	0.19
chr3_16843338_16843591	0.12	PLCL2	phospholipase C-like 2	82988	0.1
chr3_46935271_46935422	0.12	AC109583.1	Uncharacterized protein	5175	0.16
chr6_135518184_135518665	0.10	MYB-AS1	MYB antisense RNA 1	1291	0.44
chr10_8284374_8284525	0.10	GATA3	GATA binding protein 3	187680	0.03
chr9_100395113_100395272	0.10	TSTD2	thiosulfate sulfurtransferase (rhodanese)-like domain containing 2	665	0.42
chr3_134092582_134092733	0.09	AMOTL2	angiomotin like 2	18	0.98
chr11_59279292_59279443	0.09	OR4D9	olfactory receptor, family 4, subfamily D, member 9	3019	0.16
chr7_100464718_100465052	0.09	TRIP6	thyroid hormone receptor interactor 6	125	0.92
chr14_100112045_100112211	0.09	HHIPL1	HHIP-like 1	648	0.71
chrX_19770106_19770364	0.09	SH3KBP1	SH3-domain kinase binding protein 1	4414	0.34
chr3_32451109_32451284	0.09	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	17665	0.23
chr2_111740835_111740986	0.09	ACOXL	acyl-CoA oxidase-like	3865	0.35
chr5_64331605_64331756	0.08	ENSG00000207439	.	87516	0.1
chr17_62032388_62032539	0.08	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	17815	0.11
chr1_198904060_198904298	0.08	ENSG00000207759	.	75897	0.11
chr20_25007310_25007600	0.07	ACSS1	acyl-CoA synthetase short-chain family member 1	5853	0.21
chr13_111227788_111227989	0.07	RAB20	RAB20, member RAS oncogene family	13808	0.2
chr10_82181789_82181952	0.07	FAM213A	family with sequence similarity 213, member A	2116	0.32
chr3_62304486_62304637	0.07	ENSG00000241472	.	6	0.57
chr2_219926016_219926467	0.06	IHH	indian hedgehog	1052	0.34
chr8_6114669_6114820	0.06	RP11-115C21.2		149319	0.04
chr13_33646591_33646742	0.06	ENSG00000221677	.	31177	0.19
chr6_156968465_156968883	0.06	ARID1B	AT rich interactive domain 1B (SWI1-like)	130389	0.05
chr11_45831767_45831918	0.06	SLC35C1	solute carrier family 35 (GDP-fucose transporter), member C1	5142	0.18
chr1_94366888_94367039	0.06	GCLM	glutamate-cysteine ligase, modifier subunit	8003	0.19
chr10_133747286_133747437	0.06	PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	594	0.81
chr19_50861782_50862295	0.06	NAPSA	napsin A aspartic peptidase	6844	0.09
chr21_46001951_46002102	0.06	KRTAP10-5	keratin associated protein 10-5	1545	0.17
chr15_98224143_98224294	0.06	LINC00923	long intergenic non-protein coding RNA 923	193562	0.03
chr4_77212822_77212973	0.06	FAM47E-STBD1	FAM47E-STBD1 readthrough	14282	0.17
chr15_81582433_81582671	0.06	IL16	interleukin 16	6702	0.22
chr8_82100250_82100582	0.06	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	76113	0.1
chr11_60880202_60880378	0.06	CD5	CD5 molecule	10309	0.18
chr14_92346455_92346606	0.05	FBLN5	fibulin 5	2144	0.33
chr20_46369136_46369287	0.05	SULF2	sulfatase 2	45022	0.15
chr2_68612447_68612608	0.05	AC015969.3		19811	0.16
chr6_82569584_82569847	0.05	ENSG00000206886	.	95974	0.08
chr19_15579754_15579917	0.05	RASAL3	RAS protein activator like 3	4453	0.14
chr12_56731704_56731855	0.05	IL23A	interleukin 23, alpha subunit p19	884	0.33
chr19_2775823_2776196	0.05	SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	5230	0.12
chr5_176569109_176569306	0.05	NSD1	nuclear receptor binding SET domain protein 1	7102	0.21
chr5_75748396_75748547	0.05	IQGAP2	IQ motif containing GTPase activating protein 2	48222	0.17
chr21_34707233_34707384	0.05	IFNAR1	interferon (alpha, beta and omega) receptor 1	10030	0.18
chr21_46898650_46899022	0.05	COL18A1	collagen, type XVIII, alpha 1	11353	0.2
chr5_59437071_59437222	0.04	PDE4D	phosphodiesterase 4D, cAMP-specific	44279	0.19
chr6_16569798_16569949	0.04	ENSG00000265642	.	141119	0.05
chrX_109249032_109249228	0.04	TMEM164	transmembrane protein 164	2787	0.34
chr6_16749772_16749987	0.04	RP1-151F17.1		11490	0.24
chr12_3857937_3858128	0.04	EFCAB4B	EF-hand calcium binding domain 4B	4231	0.27
chr1_32810829_32811029	0.04	TSSK3	testis-specific serine kinase 3	8126	0.12
chr10_48289621_48289908	0.04	ANXA8	annexin A8	34411	0.11
chrX_135724373_135724536	0.04	ENSG00000233093	.	2628	0.24
chr2_51452608_51452759	0.04	NRXN1	neurexin 1	193009	0.03
chr17_79328867_79329074	0.04	TMEM105	transmembrane protein 105	24496	0.11
chr6_73904661_73904812	0.04	KHDC1P1	KH homology domain containing 1 pseudogene 1	15067	0.15
chr17_65505786_65506259	0.04	CTD-2653B5.1		14575	0.17
chr20_56967400_56967551	0.04	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	3106	0.31
chr10_103608236_103608387	0.03	KCNIP2	Kv channel interacting protein 2	4634	0.19
chr9_92110830_92111100	0.03	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1382	0.41
chr5_61612133_61612284	0.03	KIF2A	kinesin heavy chain member 2A	4568	0.3
chr22_30662165_30662316	0.03	OSM	oncostatin M	433	0.7
chr3_101555850_101556001	0.03	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	9088	0.19
chr2_217641332_217641483	0.03	ENSG00000222832	.	16916	0.18
chr2_198575264_198575450	0.03	MARS2	methionyl-tRNA synthetase 2, mitochondrial	5270	0.2
chr14_58605715_58605866	0.03	C14orf37	chromosome 14 open reading frame 37	13141	0.19
chr13_52209380_52209601	0.03	ENSG00000242893	.	41139	0.12
chr17_75531537_75531688	0.03	SEPT9	septin 9	53617	0.12
chr11_77785895_77786046	0.03	NDUFC2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	4895	0.12
chr6_36076165_36076316	0.03	MAPK13	mitogen-activated protein kinase 13	21858	0.16
chr22_39745336_39745494	0.03	SYNGR1	synaptogyrin 1	515	0.69
chr3_193461847_193462134	0.03	ENSG00000243991	.	3480	0.32
chr16_50742452_50742934	0.03	NOD2	nucleotide-binding oligomerization domain containing 2	3412	0.14
chr11_12695755_12695947	0.03	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	118	0.98
chr11_77524472_77524623	0.03	RSF1	remodeling and spacing factor 1	7205	0.15
chr8_30762092_30762243	0.03	TEX15	testis expressed 15	55559	0.14
chr17_76749954_76750222	0.03	CYTH1	cytohesin 1	17116	0.18
chr8_27222091_27222616	0.03	PTK2B	protein tyrosine kinase 2 beta	15815	0.21
chr7_138393128_138393279	0.03	SVOPL	SVOP-like	7106	0.24
chr15_48469683_48470033	0.03	MYEF2	myelin expression factor 2	692	0.6
chr9_124091436_124091643	0.03	GSN	gelsolin	2679	0.21
chrX_56791597_56791859	0.03	ENSG00000204272	.	36036	0.23
chr13_97876107_97876342	0.02	MBNL2	muscleblind-like splicing regulator 2	1615	0.53
chr7_132350846_132351136	0.02	AC009365.3		17438	0.2
chr20_61808362_61808898	0.02	ENSG00000207598	.	1222	0.4
chr8_74792715_74792866	0.02	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	1645	0.41
chr10_73520995_73521418	0.02	C10orf54	chromosome 10 open reading frame 54	3819	0.23
chr5_87963475_87963729	0.02	ENSG00000245526	.	845	0.63
chr1_40860718_40861074	0.02	SMAP2	small ArfGAP2	1611	0.36
chr17_62141355_62141640	0.02	ICAM2	intercellular adhesion molecule 2	43503	0.11
chr13_113664073_113664237	0.02	RP11-120K24.5		170	0.9
chr13_41139475_41139713	0.02	AL133318.1	Uncharacterized protein	28271	0.22
chr10_50452094_50452371	0.02	C10orf71-AS1	C10orf71 antisense RNA 1	54593	0.1
chr7_8297929_8298080	0.02	ICA1	islet cell autoantigen 1, 69kDa	3678	0.21
chr3_38079216_38079504	0.02	DLEC1	deleted in lung and esophageal cancer 1	1336	0.35
chr5_158176936_158177087	0.02	CTD-2363C16.1		233003	0.02
chr21_44184193_44184344	0.02	AP001627.1		22400	0.2
chr6_2111445_2111677	0.02	GMDS	GDP-mannose 4,6-dehydratase	64664	0.15
chr13_107862893_107863044	0.02	ENSG00000221316	.	89587	0.09
chr4_2284128_2284303	0.02	ZFYVE28	zinc finger, FYVE domain containing 28	5227	0.14
chr1_205779229_205779380	0.02	SLC41A1	solute carrier family 41 (magnesium transporter), member 1	3000	0.23
chrX_135848042_135848429	0.02	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1267	0.45
chr17_62972703_62972949	0.02	AMZ2P1	archaelysin family metallopeptidase 2 pseudogene 1	3191	0.2
chr19_14117646_14117797	0.02	RFX1	regulatory factor X, 1 (influences HLA class II expression)	624	0.56
chr7_74837064_74837215	0.02	AC004878.2		18173	0.13
chr17_63048049_63048280	0.02	RP11-583F2.5		137	0.96
chr10_126672174_126672466	0.02	CTBP2	C-terminal binding protein 2	22262	0.16
chr18_3277346_3277526	0.02	MYL12B	myosin, light chain 12B, regulatory	14482	0.16
chr12_133022629_133022780	0.02	MUC8	mucin 8	28022	0.17
chr9_245521_245672	0.02	RP11-59O6.3		27406	0.15
chr1_9790555_9790706	0.02	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	12503	0.17
chr8_10697366_10697517	0.02	PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	55	0.51
chr15_65576232_65576450	0.02	ENSG00000206903	.	1588	0.26
chr14_76010271_76010422	0.02	BATF	basic leucine zipper transcription factor, ATF-like	21443	0.15
chr19_5687992_5688143	0.02	RPL36	ribosomal protein L36	2140	0.17
chr22_24555252_24555403	0.02	CABIN1	calcineurin binding protein 1	3521	0.21
chr2_144075020_144075171	0.02	RP11-190J23.1		145354	0.04
chr7_38309731_38309882	0.02	STARD3NL	STARD3 N-terminal like	91809	0.09
chr2_228312998_228313149	0.01	ENSG00000266382	.	23775	0.17
chr21_27457592_27457743	0.01	APP	amyloid beta (A4) precursor protein	4710	0.29
chr14_22457517_22457668	0.01	ENSG00000238634	.	153295	0.04
chr19_45625479_45625630	0.01	AC005757.6		14681	0.09
chr22_45664092_45664243	0.01	UPK3A	uroplakin 3A	16696	0.16
chr7_76266405_76266556	0.01	POMZP3	POM121 and ZP3 fusion	9922	0.22
chr17_2516877_2517028	0.01	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	19912	0.14
chr1_244396134_244396285	0.01	C1orf100	chromosome 1 open reading frame 100	119728	0.05
chr20_62580456_62580607	0.01	UCKL1	uridine-cytidine kinase 1-like 1	1948	0.13
chr7_75081723_75081874	0.01	POM121C	POM121 transmembrane nucleoporin C	9805	0.13
chr1_167193026_167193202	0.01	POU2F1	POU class 2 homeobox 1	2971	0.23
chr11_66059435_66059843	0.01	TMEM151A	transmembrane protein 151A	298	0.71
chr1_22380057_22380208	0.01	CDC42	cell division cycle 42	342	0.82
chr6_32164359_32164510	0.01	NOTCH4	notch 4	921	0.28
chr9_80362813_80362964	0.01	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	75027	0.11
chr11_12071055_12071206	0.01	DKK3	dickkopf WNT signaling pathway inhibitor 3	39814	0.17
chr16_90021030_90021181	0.01	DEF8	differentially expressed in FDCP 8 homolog (mouse)	525	0.64
chr7_50535965_50536168	0.01	FIGNL1	fidgetin-like 1	17978	0.2
chr3_140693787_140693938	0.01	RP11-231L11.3		2276	0.36
chr22_32805402_32805689	0.01	RTCB	RNA 2',3'-cyclic phosphate and 5'-OH ligase	2679	0.22
chr3_107646211_107646473	0.01	BBX	bobby sox homolog (Drosophila)	128904	0.06
chr17_5365759_5365910	0.01	DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33	6234	0.12
chr19_11074648_11074881	0.01	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	2767	0.19
chr17_75425276_75425533	0.01	SEPT9	septin 9	2366	0.24
chr1_47060894_47061171	0.01	MKNK1	MAP kinase interacting serine/threonine kinase 1	301	0.87
chr6_37891842_37892090	0.01	ZFAND3	zinc finger, AN1-type domain 3	5769	0.23
chr5_139930646_139930797	0.01	SRA1	steroid receptor RNA activator 1	8	0.94
chr2_37062565_37062716	0.01	AC007382.1	Uncharacterized protein	5890	0.23
chr14_25103522_25103673	0.01	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	124	0.96
chr10_112016537_112016688	0.01	MXI1	MAX interactor 1, dimerization protein	29175	0.18
chr1_151445359_151445526	0.01	POGZ	pogo transposable element with ZNF domain	13501	0.11
chr22_29191548_29191699	0.01	XBP1	X-box binding protein 1	4498	0.15
chr8_134501895_134502046	0.01	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	27	0.99
chr19_19538149_19538407	0.01	GATAD2A	GATA zinc finger domain containing 2A	47	0.96
chr5_130870514_130870903	0.01	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	1982	0.48
chr16_17091340_17091491	0.01	CTD-2576D5.4		136946	0.05
chr17_66242892_66243078	0.01	AMZ2	archaelysin family metallopeptidase 2	730	0.5
chr22_44207665_44207833	0.01	EFCAB6	EF-hand calcium binding domain 6	321	0.69
chr19_16205574_16205925	0.01	TPM4	tropomyosin 4	1367	0.36
chr5_102729544_102729916	0.01	C5orf30	chromosome 5 open reading frame 30	134605	0.05
chr22_46025392_46025543	0.01	ENSG00000251985	.	4955	0.22
chr3_32445320_32445471	0.01	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	11864	0.25
chrX_39169100_39169251	0.00	ENSG00000207122	.	228637	0.02
chr9_79218995_79219152	0.00	ENSG00000241781	.	32342	0.18
chr10_34411268_34411541	0.00	ENSG00000199200	.	79598	0.12
chr1_32389459_32389792	0.00	PTP4A2	protein tyrosine phosphatase type IVA, member 2	4541	0.2
chr7_43641940_43642091	0.00	STK17A	serine/threonine kinase 17a	19351	0.17
chr11_118755028_118755179	0.00	CXCR5	chemokine (C-X-C motif) receptor 5	628	0.54
chr5_68660810_68660961	0.00	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	1763	0.28
chr16_2178397_2178612	0.00	ENSG00000200059	.	3348	0.07
chr22_40768850_40769001	0.00	SGSM3	small G protein signaling modulator 3	2290	0.25
chr2_152220395_152220546	0.00	ENSG00000264684	.	4378	0.19
chr8_74889988_74890139	0.00	TMEM70	transmembrane protein 70	1619	0.27
chr9_83990440_83990591	0.00	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	237922	0.02
chr3_158288758_158289050	0.00	MLF1	myeloid leukemia factor 1	48	0.5
chr15_33122968_33123119	0.00	FMN1	formin 1	57412	0.12
chr6_30118578_30118729	0.00	TRIM10	tripartite motif containing 10	10058	0.1
chr2_235383990_235384141	0.00	ARL4C	ADP-ribosylation factor-like 4C	21179	0.29
chr20_42575036_42575187	0.00	TOX2	TOX high mobility group box family member 2	766	0.73
chr2_28114153_28114304	0.00	RBKS	ribokinase	263	0.74
chr2_43036312_43036514	0.00	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	16681	0.23
chr12_27939071_27939324	0.00	RP11-860B13.1		5197	0.13
chr3_115231996_115232281	0.00	GAP43	growth associated protein 43	110033	0.07

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)