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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BBX

Z-value: 2.09

Motif logo

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Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
ENSG00000114439.14 BBX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
BBXchr3_107516918_1075170694450.909528-0.872.1e-03Click!
BBXchr3_107531680_107531831143170.308123-0.771.5e-02Click!
BBXchr3_107279086_107279237349120.2375050.752.0e-02Click!
BBXchr3_107516294_1075165909960.718673-0.732.6e-02Click!
BBXchr3_107296202_107296353218830.2826510.723.0e-02Click!

Activity of the BBX motif across conditions

Conditions sorted by the z-value of the BBX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_110570725_110571085 0.88 CAMK4
calcium/calmodulin-dependent protein kinase IV
11121
0.22
chr17_66343606_66343891 0.87 ARSG
arylsulfatase G
56089
0.1
chr7_8166102_8166400 0.85 AC006042.6

12596
0.21
chr21_19148494_19148866 0.83 AL109761.5

17125
0.22
chr3_101240562_101240818 0.69 SENP7
SUMO1/sentrin specific peptidase 7
8605
0.16
chrX_152608723_152608874 0.68 ZNF275
zinc finger protein 275
858
0.57
chr7_76984255_76984448 0.64 GSAP
gamma-secretase activating protein
24667
0.21
chr2_158274337_158274948 0.63 CYTIP
cytohesin 1 interacting protein
21284
0.2
chr15_22474307_22474699 0.63 IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
1150
0.36
chrX_19762386_19762616 0.62 SH3KBP1
SH3-domain kinase binding protein 1
2028
0.47
chr7_106509634_106509916 0.62 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
3851
0.32
chr1_28217565_28217790 0.62 RPA2
replication protein A2, 32kDa
5919
0.13
chr1_160684089_160684457 0.61 CD48
CD48 molecule
2632
0.23
chr1_169672251_169672700 0.61 SELL
selectin L
8364
0.2
chr10_65033826_65034075 0.60 JMJD1C
jumonji domain containing 1C
4968
0.31
chr8_48511093_48511421 0.60 SPIDR
scaffolding protein involved in DNA repair
60969
0.12
chr2_114666842_114667060 0.57 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
18776
0.21
chr5_156616881_156617104 0.57 ITK
IL2-inducible T-cell kinase
9155
0.13
chr1_28525614_28525786 0.57 AL353354.2

1370
0.23
chr10_120832612_120832844 0.56 EIF3A
eukaryotic translation initiation factor 3, subunit A
7303
0.13
chr11_35147581_35147732 0.56 AL356215.1

2559
0.25
chr9_98649500_98649877 0.56 ERCC6L2
excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2
11705
0.19
chr12_68843231_68843501 0.55 MDM1
Mdm1 nuclear protein homolog (mouse)
117205
0.06
chr12_42739005_42739156 0.55 PPHLN1
periphilin 1
1474
0.31
chr3_71768005_71768373 0.55 EIF4E3
eukaryotic translation initiation factor 4E family member 3
6337
0.24
chr3_151916440_151916649 0.54 MBNL1
muscleblind-like splicing regulator 1
69285
0.11
chr7_3134184_3134615 0.54 CARD11
caspase recruitment domain family, member 11
50820
0.14
chr19_6814065_6814233 0.53 VAV1
vav 1 guanine nucleotide exchange factor
30020
0.12
chr4_153385916_153386290 0.53 ENSG00000264678
.
24465
0.2
chr15_87159734_87160062 0.53 RP11-182L7.1

14469
0.3
chr6_143211483_143211634 0.53 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
53374
0.15
chr6_166827899_166828050 0.52 RP1-168L15.5

31297
0.14
chr6_24937638_24937929 0.52 FAM65B
family with sequence similarity 65, member B
1595
0.45
chr14_72020524_72020893 0.52 SIPA1L1
signal-induced proliferation-associated 1 like 1
24666
0.25
chr18_56381121_56381430 0.52 RP11-126O1.4

36429
0.12
chr5_156623615_156623766 0.51 ITK
IL2-inducible T-cell kinase
15853
0.12
chr4_109031937_109032201 0.51 LEF1
lymphoid enhancer-binding factor 1
55388
0.13
chr8_129618278_129618429 0.51 ENSG00000221351
.
213687
0.02
chr5_67575496_67575886 0.51 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
377
0.92
chr11_108067830_108068158 0.51 ATM
ataxia telangiectasia mutated
25217
0.14
chr20_43603773_43603967 0.51 STK4
serine/threonine kinase 4
8703
0.15
chr7_55538938_55539284 0.50 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
44659
0.17
chr21_14917426_14917595 0.50 POTED
POTE ankyrin domain family, member D
64988
0.11
chr8_116679060_116679211 0.50 TRPS1
trichorhinophalangeal syndrome I
1073
0.69
chr16_11879926_11880367 0.49 ZC3H7A
zinc finger CCCH-type containing 7A
3256
0.2
chr20_49543994_49544145 0.49 ADNP
activity-dependent neuroprotector homeobox
1284
0.34
chr1_169668847_169669156 0.49 SELL
selectin L
11838
0.19
chr3_56848664_56848815 0.49 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
12744
0.28
chr17_14102455_14103001 0.49 AC005224.2

11077
0.2
chr7_50250289_50250673 0.48 AC020743.2

68062
0.11
chr6_36085891_36086042 0.48 MAPK13
mitogen-activated protein kinase 13
12132
0.17
chr12_9770182_9770386 0.48 ENSG00000212345
.
6540
0.14
chr8_67571163_67571314 0.47 ENSG00000201365
.
5534
0.15
chr14_98656916_98657071 0.47 ENSG00000222066
.
141094
0.05
chr18_77747820_77747971 0.47 TXNL4A
thioredoxin-like 4A
642
0.71
chr4_84134177_84134460 0.47 COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
71600
0.1
chr15_45009098_45009249 0.47 B2M
beta-2-microglobulin
5458
0.16
chr3_113952777_113952998 0.47 ZNF80
zinc finger protein 80
3538
0.21
chr7_50411027_50411610 0.47 IKZF1
IKAROS family zinc finger 1 (Ikaros)
44073
0.17
chr4_78727930_78728100 0.47 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
12202
0.26
chr6_35566907_35567293 0.46 ENSG00000212579
.
52495
0.1
chr17_78637163_78637475 0.46 RPTOR
regulatory associated protein of MTOR, complex 1
118051
0.05
chr1_112048866_112049017 0.46 ADORA3
adenosine A3 receptor
2559
0.18
chr5_10644341_10644555 0.46 ANKRD33B-AS1
ANKRD33B antisense RNA 1
16111
0.23
chr1_198624932_198625124 0.45 RP11-553K8.5

11162
0.23
chr2_175489840_175490226 0.45 WIPF1
WAS/WASL interacting protein family, member 1
9274
0.21
chr15_38854255_38854406 0.45 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
1850
0.35
chr14_55900173_55900517 0.45 TBPL2
TATA box binding protein like 2
6989
0.23
chr2_173084767_173084918 0.45 ENSG00000238572
.
63994
0.12
chr7_36817273_36817729 0.45 AOAH
acyloxyacyl hydrolase (neutrophil)
53347
0.14
chr12_90096202_90096439 0.45 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
6288
0.22
chr1_198589922_198590135 0.45 PTPRC
protein tyrosine phosphatase, receptor type, C
17773
0.23
chr19_42705324_42705478 0.44 ENSG00000265122
.
8171
0.09
chr3_56627315_56627668 0.44 CCDC66
coiled-coil domain containing 66
34711
0.2
chr12_46621820_46621981 0.44 SLC38A1
solute carrier family 38, member 1
39584
0.21
chrX_55748187_55748459 0.44 RRAGB
Ras-related GTP binding B
4005
0.3
chr9_20740624_20740775 0.44 ENSG00000207609
.
24595
0.17
chr5_122760226_122760377 0.44 CEP120
centrosomal protein 120kDa
1015
0.66
chr2_42533183_42533346 0.44 EML4
echinoderm microtubule associated protein like 4
4871
0.28
chr20_35583518_35583882 0.44 SAMHD1
SAM domain and HD domain 1
3454
0.28
chr18_46558522_46558673 0.44 RP11-15F12.1

8524
0.2
chr2_74216204_74216476 0.44 DGUOK-AS1
DGUOK antisense RNA 1
7772
0.16
chr18_14613147_14613333 0.44 POTEC
POTE ankyrin domain family, member C
70095
0.11
chr12_69555624_69555775 0.43 ENSG00000252547
.
44267
0.16
chr5_35835098_35835339 0.43 CTD-2113L7.1

8098
0.2
chr7_8022696_8022847 0.43 AC006042.7

13237
0.18
chr14_61800103_61800254 0.43 PRKCH
protein kinase C, eta
6547
0.21
chr9_111605811_111605962 0.43 ACTL7B
actin-like 7B
13353
0.2
chr3_141222680_141222888 0.43 RASA2
RAS p21 protein activator 2
16893
0.2
chr12_46364802_46364953 0.42 SCAF11
SR-related CTD-associated factor 11
19471
0.26
chr10_22931039_22931318 0.42 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
50536
0.17
chr1_169674701_169674897 0.42 SELL
selectin L
6040
0.21
chr15_61101412_61101594 0.42 RP11-554D20.1

44564
0.17
chr5_169718481_169718670 0.42 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
6656
0.24
chr13_108918512_108918812 0.42 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
3315
0.27
chr7_38335017_38335168 0.42 STARD3NL
STARD3 N-terminal like
117095
0.06
chr10_90721521_90721738 0.42 ACTA2
actin, alpha 2, smooth muscle, aorta
9099
0.15
chr17_65459455_65459718 0.42 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
5932
0.15
chr3_40506059_40506320 0.42 RPL14
ribosomal protein L14
7344
0.15
chr4_38484324_38484475 0.42 RP11-617D20.1

141797
0.04
chr15_57329097_57329248 0.42 ENSG00000222586
.
70577
0.12
chr12_46611039_46611249 0.42 SLC38A1
solute carrier family 38, member 1
50340
0.18
chr2_160579118_160579420 0.42 MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
10251
0.25
chr7_130675648_130675832 0.41 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
6872
0.27
chr10_26772022_26772210 0.41 ENSG00000199733
.
26402
0.22
chr17_38018991_38019172 0.41 IKZF3
IKAROS family zinc finger 3 (Aiolos)
1298
0.36
chr21_48062534_48062685 0.41 PRMT2
protein arginine methyltransferase 2
1646
0.44
chr4_81503275_81503427 0.41 C4orf22
chromosome 4 open reading frame 22
246428
0.02
chr2_144116700_144116851 0.41 AC096558.1

121575
0.06
chr10_14576882_14577033 0.41 FAM107B
family with sequence similarity 107, member B
2248
0.38
chr9_132757208_132757359 0.41 FNBP1
formin binding protein 1
137
0.97
chrX_131871644_131871795 0.40 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
29063
0.23
chrX_123146711_123147006 0.40 STAG2
stromal antigen 2
49838
0.15
chr4_84271786_84272009 0.40 HPSE
heparanase
15591
0.23
chr5_66452974_66453257 0.40 MAST4
microtubule associated serine/threonine kinase family member 4
14853
0.25
chr1_10367885_10368145 0.40 ENSG00000264501
.
1492
0.35
chr8_19331372_19331680 0.40 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
127850
0.06
chr11_118178245_118178503 0.40 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
2760
0.18
chr10_12238940_12239179 0.40 CDC123
cell division cycle 123
828
0.39
chr1_150064532_150064735 0.40 VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
24748
0.14
chr1_19990632_19990980 0.40 HTR6
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
974
0.53
chr2_120679416_120679567 0.40 ENSG00000238368
.
4597
0.25
chr4_122102125_122102631 0.40 ENSG00000252183
.
11680
0.22
chr2_233178045_233178196 0.40 DIS3L2
DIS3 mitotic control homolog (S. cerevisiae)-like 2
20533
0.17
chr20_34316014_34316165 0.40 RBM39
RNA binding motif protein 39
1177
0.34
chr8_42009241_42009403 0.40 RP11-589C21.5

959
0.41
chr6_158779170_158779472 0.40 RP11-732M18.2

40272
0.15
chr7_50370236_50370512 0.39 IKZF1
IKAROS family zinc finger 1 (Ikaros)
3129
0.36
chr20_5572612_5572900 0.39 GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
16602
0.24
chr2_144004181_144004578 0.39 RP11-190J23.1

74638
0.12
chr14_90427057_90427257 0.39 TDP1
tyrosyl-DNA phosphodiesterase 1
2292
0.33
chr10_115625589_115625781 0.39 NHLRC2
NHL repeat containing 2
11265
0.17
chr10_28835021_28835418 0.39 WAC
WW domain containing adaptor with coiled-coil
12167
0.2
chr6_106099067_106099218 0.39 PREP
prolyl endopeptidase
248183
0.02
chr16_77229238_77229389 0.39 SYCE1L
synaptonemal complex central element protein 1-like
3981
0.21
chr8_129063151_129063374 0.39 ENSG00000221176
.
1864
0.37
chrX_149860118_149860300 0.39 MTMR1
myotubularin related protein 1
1226
0.6
chr8_41999804_41999957 0.39 RP11-589C21.5

10401
0.17
chr4_68425690_68425841 0.39 STAP1
signal transducing adaptor family member 1
1319
0.49
chrX_135053925_135054076 0.39 MMGT1
membrane magnesium transporter 1
2106
0.31
chr8_10189818_10189969 0.39 MSRA
methionine sulfoxide reductase A
30848
0.21
chr18_77173067_77173218 0.39 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
12750
0.24
chr12_15109847_15109998 0.39 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
4278
0.19
chr6_52151332_52151486 0.39 MCM3
minichromosome maintenance complex component 3
1774
0.39
chr3_18820139_18820372 0.39 ENSG00000228956
.
33019
0.25
chr1_36885062_36885213 0.39 ENSG00000201448
.
958
0.42
chr11_60873950_60874231 0.39 CD5
CD5 molecule
4109
0.21
chr15_60267965_60268474 0.39 FOXB1
forkhead box B1
28202
0.25
chr8_19558054_19558332 0.39 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
17921
0.28
chr11_14099941_14100092 0.38 ENSG00000212365
.
56516
0.16
chr11_128169809_128169960 0.38 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
205405
0.03
chr17_14098435_14098657 0.38 AC005224.2

15259
0.19
chr5_156652592_156652883 0.38 CTB-4E7.1

1347
0.34
chr11_35220930_35221081 0.38 CD44
CD44 molecule (Indian blood group)
1625
0.33
chr6_44969408_44969559 0.38 SUPT3H
suppressor of Ty 3 homolog (S. cerevisiae)
46236
0.2
chr13_26449514_26449665 0.38 AL138815.2
Uncharacterized protein
3090
0.27
chr3_16329108_16329574 0.38 OXNAD1
oxidoreductase NAD-binding domain containing 1
18593
0.15
chr5_118654684_118654873 0.38 ENSG00000243333
.
12452
0.19
chr1_14058081_14058259 0.38 PRDM2
PR domain containing 2, with ZNF domain
17728
0.21
chr6_90813480_90813638 0.38 ENSG00000222078
.
102334
0.07
chr10_22933738_22933949 0.38 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
53201
0.16
chr21_36417555_36417706 0.38 RUNX1
runt-related transcription factor 1
3832
0.38
chr12_68025335_68025706 0.38 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
16598
0.25
chrX_134518932_134519216 0.38 ZNF449
zinc finger protein 449
40353
0.13
chr2_7018212_7018651 0.38 RSAD2
radical S-adenosyl methionine domain containing 2
494
0.78
chr15_44958213_44958403 0.38 PATL2
protein associated with topoisomerase II homolog 2 (yeast)
2375
0.21
chr13_99876727_99876878 0.38 ENSG00000201793
.
18840
0.17
chr1_111208863_111209034 0.38 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
8707
0.18
chr8_22389811_22389962 0.38 RP11-582J16.4

13032
0.11
chr1_169672704_169673057 0.38 SELL
selectin L
7959
0.2
chr6_167470073_167470306 0.38 CCR6
chemokine (C-C motif) receptor 6
55106
0.09
chr10_111840656_111840849 0.37 ADD3
adducin 3 (gamma)
73030
0.1
chr17_33857619_33857982 0.37 SLFN12L
schlafen family member 12-like
7080
0.12
chr1_101706352_101706538 0.37 RP4-575N6.5

2269
0.24
chr12_39725210_39725597 0.37 KIF21A
kinesin family member 21A
726
0.8
chr1_9717829_9718205 0.37 C1orf200
chromosome 1 open reading frame 200
3373
0.21
chr10_6597209_6597469 0.37 PRKCQ
protein kinase C, theta
24862
0.26
chr5_66512764_66513039 0.37 CD180
CD180 molecule
20274
0.26
chr8_128505801_128505952 0.37 CASC8
cancer susceptibility candidate 8 (non-protein coding)
11492
0.29
chr6_130544442_130544610 0.37 SAMD3
sterile alpha motif domain containing 3
427
0.9
chr2_28845314_28845495 0.37 PLB1
phospholipase B1
8049
0.21
chr1_180397322_180397473 0.37 ENSG00000265435
.
10128
0.24
chr4_154730657_154731010 0.37 SFRP2
secreted frizzled-related protein 2
20561
0.19
chrX_78618581_78618732 0.37 ITM2A
integral membrane protein 2A
4200
0.37
chr3_176825153_176825340 0.37 ENSG00000201343
.
13342
0.21
chr8_131017510_131017704 0.37 ENSG00000253043
.
760
0.61
chr6_16483008_16483237 0.37 ENSG00000265642
.
54368
0.17
chr6_144676059_144676210 0.37 UTRN
utrophin
10897
0.25
chr6_112069480_112069631 0.36 FYN
FYN oncogene related to SRC, FGR, YES
10762
0.26
chr3_111265770_111265929 0.36 CD96
CD96 molecule
4852
0.28
chr5_96267886_96268086 0.36 LNPEP
leucyl/cystinyl aminopeptidase
3182
0.23
chr15_44852872_44853058 0.36 RP11-151N17.1

2938
0.2
chr4_83282407_83282629 0.36 HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
1726
0.36
chr1_100917053_100917204 0.36 RP5-837M10.4

34425
0.17
chr19_19726701_19727139 0.36 PBX4
pre-B-cell leukemia homeobox 4
2805
0.16
chr1_52888786_52889059 0.36 ZCCHC11
zinc finger, CCHC domain containing 11
7831
0.14
chr2_103007589_103007741 0.36 IL18RAP
interleukin 18 receptor accessory protein
27484
0.12
chr9_74291840_74291991 0.36 TMEM2
transmembrane protein 2
27933
0.26
chr1_192484853_192485075 0.36 ENSG00000221145
.
24614
0.2
chr10_11223388_11223701 0.36 RP3-323N1.2

10205
0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of BBX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.7 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.8 GO:0002517 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.2 0.5 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.4 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.4 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.8 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0051497 negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1 4.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.5 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.3 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.1 GO:0002507 tolerance induction(GO:0002507)
0.1 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.2 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.2 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.1 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0042267 natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.1 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.5 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.2 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.2 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.5 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0033079 immature T cell proliferation(GO:0033079) immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation(GO:0033083) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0045916 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0046719 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0036260 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.3 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.0 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0032109 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0042428 serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.6 GO:0016236 macroautophagy(GO:0016236)
0.0 0.1 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0070897 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.0 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.3 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.0 GO:0045117 azole transport(GO:0045117)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.2 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.7 GO:0006885 regulation of pH(GO:0006885)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0045010 actin nucleation(GO:0045010)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0051095 regulation of helicase activity(GO:0051095)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.0 GO:2000401 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0042921 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.0 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.0 0.1 GO:0015872 dopamine transport(GO:0015872)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.0 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.1 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0031065 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0 0.0 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 1.3 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0001840 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0032727 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.7 GO:1902403 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:1903504 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0007260 tyrosine phosphorylation of STAT protein(GO:0007260)
0.0 0.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:0032722 positive regulation of chemokine production(GO:0032722)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1903831 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) response to ammonium ion(GO:0060359) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0051132 natural killer cell proliferation(GO:0001787) NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0071554 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0070234 positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0043266 regulation of potassium ion transport(GO:0043266)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.0 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0033483 gas homeostasis(GO:0033483)
0.0 0.6 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.3 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.0 GO:0048937 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 0.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.2 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 2.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.0 GO:1901663 quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:2000117 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.2 GO:0000805 X chromosome(GO:0000805) Barr body(GO:0001740)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.6 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.0 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0016604 nuclear body(GO:0016604)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.7 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.1 GO:0001846 opsonin binding(GO:0001846)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.5 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.0 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 1.0 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.0 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.2 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.0 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI