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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for BBX

Z-value: 2.09

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Transcription factors associated with BBX

Gene Symbol	Gene ID	Gene Info
BBX Ensembl NCBI GeneCards UniProt	ENSG00000114439.14	BBX high mobility group box domain containing

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_107516918_107517069	BBX	445	0.909528	-0.87	2.1e-03	Click!
chr3_107531680_107531831	BBX	14317	0.308123	-0.77	1.5e-02	Click!
chr3_107279086_107279237	BBX	34912	0.237505	0.75	2.0e-02	Click!
chr3_107516294_107516590	BBX	996	0.718673	-0.73	2.6e-02	Click!
chr3_107296202_107296353	BBX	21883	0.282651	0.72	3.0e-02	Click!

Activity of the BBX motif across conditions

Conditions sorted by the z-value of the BBX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_110570725_110571085	0.88	CAMK4	calcium/calmodulin-dependent protein kinase IV	11121	0.22
chr17_66343606_66343891	0.87	ARSG	arylsulfatase G	56089	0.1
chr7_8166102_8166400	0.85	AC006042.6		12596	0.21
chr21_19148494_19148866	0.83	AL109761.5		17125	0.22
chr3_101240562_101240818	0.69	SENP7	SUMO1/sentrin specific peptidase 7	8605	0.16
chrX_152608723_152608874	0.68	ZNF275	zinc finger protein 275	858	0.57
chr7_76984255_76984448	0.64	GSAP	gamma-secretase activating protein	24667	0.21
chr2_158274337_158274948	0.63	CYTIP	cytohesin 1 interacting protein	21284	0.2
chr15_22474307_22474699	0.63	IGHV4OR15-8	immunoglobulin heavy variable 4/OR15-8 (non-functional)	1150	0.36
chrX_19762386_19762616	0.62	SH3KBP1	SH3-domain kinase binding protein 1	2028	0.47
chr7_106509634_106509916	0.62	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	3851	0.32
chr1_28217565_28217790	0.62	RPA2	replication protein A2, 32kDa	5919	0.13
chr1_160684089_160684457	0.61	CD48	CD48 molecule	2632	0.23
chr1_169672251_169672700	0.61	SELL	selectin L	8364	0.2
chr10_65033826_65034075	0.60	JMJD1C	jumonji domain containing 1C	4968	0.31
chr8_48511093_48511421	0.60	SPIDR	scaffolding protein involved in DNA repair	60969	0.12
chr2_114666842_114667060	0.57	ACTR3	ARP3 actin-related protein 3 homolog (yeast)	18776	0.21
chr5_156616881_156617104	0.57	ITK	IL2-inducible T-cell kinase	9155	0.13
chr1_28525614_28525786	0.57	AL353354.2		1370	0.23
chr10_120832612_120832844	0.56	EIF3A	eukaryotic translation initiation factor 3, subunit A	7303	0.13
chr11_35147581_35147732	0.56	AL356215.1		2559	0.25
chr9_98649500_98649877	0.56	ERCC6L2	excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2	11705	0.19
chr12_68843231_68843501	0.55	MDM1	Mdm1 nuclear protein homolog (mouse)	117205	0.06
chr12_42739005_42739156	0.55	PPHLN1	periphilin 1	1474	0.31
chr3_71768005_71768373	0.55	EIF4E3	eukaryotic translation initiation factor 4E family member 3	6337	0.24
chr3_151916440_151916649	0.54	MBNL1	muscleblind-like splicing regulator 1	69285	0.11
chr7_3134184_3134615	0.54	CARD11	caspase recruitment domain family, member 11	50820	0.14
chr19_6814065_6814233	0.53	VAV1	vav 1 guanine nucleotide exchange factor	30020	0.12
chr4_153385916_153386290	0.53	ENSG00000264678	.	24465	0.2
chr15_87159734_87160062	0.53	RP11-182L7.1		14469	0.3
chr6_143211483_143211634	0.53	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	53374	0.15
chr6_166827899_166828050	0.52	RP1-168L15.5		31297	0.14
chr6_24937638_24937929	0.52	FAM65B	family with sequence similarity 65, member B	1595	0.45
chr14_72020524_72020893	0.52	SIPA1L1	signal-induced proliferation-associated 1 like 1	24666	0.25
chr18_56381121_56381430	0.52	RP11-126O1.4		36429	0.12
chr5_156623615_156623766	0.51	ITK	IL2-inducible T-cell kinase	15853	0.12
chr4_109031937_109032201	0.51	LEF1	lymphoid enhancer-binding factor 1	55388	0.13
chr8_129618278_129618429	0.51	ENSG00000221351	.	213687	0.02
chr5_67575496_67575886	0.51	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	377	0.92
chr11_108067830_108068158	0.51	ATM	ataxia telangiectasia mutated	25217	0.14
chr20_43603773_43603967	0.51	STK4	serine/threonine kinase 4	8703	0.15
chr7_55538938_55539284	0.50	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	44659	0.17
chr21_14917426_14917595	0.50	POTED	POTE ankyrin domain family, member D	64988	0.11
chr8_116679060_116679211	0.50	TRPS1	trichorhinophalangeal syndrome I	1073	0.69
chr16_11879926_11880367	0.49	ZC3H7A	zinc finger CCCH-type containing 7A	3256	0.2
chr20_49543994_49544145	0.49	ADNP	activity-dependent neuroprotector homeobox	1284	0.34
chr1_169668847_169669156	0.49	SELL	selectin L	11838	0.19
chr3_56848664_56848815	0.49	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	12744	0.28
chr17_14102455_14103001	0.49	AC005224.2		11077	0.2
chr7_50250289_50250673	0.48	AC020743.2		68062	0.11
chr6_36085891_36086042	0.48	MAPK13	mitogen-activated protein kinase 13	12132	0.17
chr12_9770182_9770386	0.48	ENSG00000212345	.	6540	0.14
chr8_67571163_67571314	0.47	ENSG00000201365	.	5534	0.15
chr14_98656916_98657071	0.47	ENSG00000222066	.	141094	0.05
chr18_77747820_77747971	0.47	TXNL4A	thioredoxin-like 4A	642	0.71
chr4_84134177_84134460	0.47	COQ2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	71600	0.1
chr15_45009098_45009249	0.47	B2M	beta-2-microglobulin	5458	0.16
chr3_113952777_113952998	0.47	ZNF80	zinc finger protein 80	3538	0.21
chr7_50411027_50411610	0.47	IKZF1	IKAROS family zinc finger 1 (Ikaros)	44073	0.17
chr4_78727930_78728100	0.47	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	12202	0.26
chr6_35566907_35567293	0.46	ENSG00000212579	.	52495	0.1
chr17_78637163_78637475	0.46	RPTOR	regulatory associated protein of MTOR, complex 1	118051	0.05
chr1_112048866_112049017	0.46	ADORA3	adenosine A3 receptor	2559	0.18
chr5_10644341_10644555	0.46	ANKRD33B-AS1	ANKRD33B antisense RNA 1	16111	0.23
chr1_198624932_198625124	0.45	RP11-553K8.5		11162	0.23
chr2_175489840_175490226	0.45	WIPF1	WAS/WASL interacting protein family, member 1	9274	0.21
chr15_38854255_38854406	0.45	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	1850	0.35
chr14_55900173_55900517	0.45	TBPL2	TATA box binding protein like 2	6989	0.23
chr2_173084767_173084918	0.45	ENSG00000238572	.	63994	0.12
chr7_36817273_36817729	0.45	AOAH	acyloxyacyl hydrolase (neutrophil)	53347	0.14
chr12_90096202_90096439	0.45	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	6288	0.22
chr1_198589922_198590135	0.45	PTPRC	protein tyrosine phosphatase, receptor type, C	17773	0.23
chr19_42705324_42705478	0.44	ENSG00000265122	.	8171	0.09
chr3_56627315_56627668	0.44	CCDC66	coiled-coil domain containing 66	34711	0.2
chr12_46621820_46621981	0.44	SLC38A1	solute carrier family 38, member 1	39584	0.21
chrX_55748187_55748459	0.44	RRAGB	Ras-related GTP binding B	4005	0.3
chr9_20740624_20740775	0.44	ENSG00000207609	.	24595	0.17
chr5_122760226_122760377	0.44	CEP120	centrosomal protein 120kDa	1015	0.66
chr2_42533183_42533346	0.44	EML4	echinoderm microtubule associated protein like 4	4871	0.28
chr20_35583518_35583882	0.44	SAMHD1	SAM domain and HD domain 1	3454	0.28
chr18_46558522_46558673	0.44	RP11-15F12.1		8524	0.2
chr2_74216204_74216476	0.44	DGUOK-AS1	DGUOK antisense RNA 1	7772	0.16
chr18_14613147_14613333	0.44	POTEC	POTE ankyrin domain family, member C	70095	0.11
chr12_69555624_69555775	0.43	ENSG00000252547	.	44267	0.16
chr5_35835098_35835339	0.43	CTD-2113L7.1		8098	0.2
chr7_8022696_8022847	0.43	AC006042.7		13237	0.18
chr14_61800103_61800254	0.43	PRKCH	protein kinase C, eta	6547	0.21
chr9_111605811_111605962	0.43	ACTL7B	actin-like 7B	13353	0.2
chr3_141222680_141222888	0.43	RASA2	RAS p21 protein activator 2	16893	0.2
chr12_46364802_46364953	0.42	SCAF11	SR-related CTD-associated factor 11	19471	0.26
chr10_22931039_22931318	0.42	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	50536	0.17
chr1_169674701_169674897	0.42	SELL	selectin L	6040	0.21
chr15_61101412_61101594	0.42	RP11-554D20.1		44564	0.17
chr5_169718481_169718670	0.42	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	6656	0.24
chr13_108918512_108918812	0.42	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	3315	0.27
chr7_38335017_38335168	0.42	STARD3NL	STARD3 N-terminal like	117095	0.06
chr10_90721521_90721738	0.42	ACTA2	actin, alpha 2, smooth muscle, aorta	9099	0.15
chr17_65459455_65459718	0.42	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	5932	0.15
chr3_40506059_40506320	0.42	RPL14	ribosomal protein L14	7344	0.15
chr4_38484324_38484475	0.42	RP11-617D20.1		141797	0.04
chr15_57329097_57329248	0.42	ENSG00000222586	.	70577	0.12
chr12_46611039_46611249	0.42	SLC38A1	solute carrier family 38, member 1	50340	0.18
chr2_160579118_160579420	0.42	MARCH7	membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase	10251	0.25
chr7_130675648_130675832	0.41	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	6872	0.27
chr10_26772022_26772210	0.41	ENSG00000199733	.	26402	0.22
chr17_38018991_38019172	0.41	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1298	0.36
chr21_48062534_48062685	0.41	PRMT2	protein arginine methyltransferase 2	1646	0.44
chr4_81503275_81503427	0.41	C4orf22	chromosome 4 open reading frame 22	246428	0.02
chr2_144116700_144116851	0.41	AC096558.1		121575	0.06
chr10_14576882_14577033	0.41	FAM107B	family with sequence similarity 107, member B	2248	0.38
chr9_132757208_132757359	0.41	FNBP1	formin binding protein 1	137	0.97
chrX_131871644_131871795	0.40	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	29063	0.23
chrX_123146711_123147006	0.40	STAG2	stromal antigen 2	49838	0.15
chr4_84271786_84272009	0.40	HPSE	heparanase	15591	0.23
chr5_66452974_66453257	0.40	MAST4	microtubule associated serine/threonine kinase family member 4	14853	0.25
chr1_10367885_10368145	0.40	ENSG00000264501	.	1492	0.35
chr8_19331372_19331680	0.40	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	127850	0.06
chr11_118178245_118178503	0.40	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	2760	0.18
chr10_12238940_12239179	0.40	CDC123	cell division cycle 123	828	0.39
chr1_150064532_150064735	0.40	VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)	24748	0.14
chr1_19990632_19990980	0.40	HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	974	0.53
chr2_120679416_120679567	0.40	ENSG00000238368	.	4597	0.25
chr4_122102125_122102631	0.40	ENSG00000252183	.	11680	0.22
chr2_233178045_233178196	0.40	DIS3L2	DIS3 mitotic control homolog (S. cerevisiae)-like 2	20533	0.17
chr20_34316014_34316165	0.40	RBM39	RNA binding motif protein 39	1177	0.34
chr8_42009241_42009403	0.40	RP11-589C21.5		959	0.41
chr6_158779170_158779472	0.40	RP11-732M18.2		40272	0.15
chr7_50370236_50370512	0.39	IKZF1	IKAROS family zinc finger 1 (Ikaros)	3129	0.36
chr20_5572612_5572900	0.39	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	16602	0.24
chr2_144004181_144004578	0.39	RP11-190J23.1		74638	0.12
chr14_90427057_90427257	0.39	TDP1	tyrosyl-DNA phosphodiesterase 1	2292	0.33
chr10_115625589_115625781	0.39	NHLRC2	NHL repeat containing 2	11265	0.17
chr10_28835021_28835418	0.39	WAC	WW domain containing adaptor with coiled-coil	12167	0.2
chr6_106099067_106099218	0.39	PREP	prolyl endopeptidase	248183	0.02
chr16_77229238_77229389	0.39	SYCE1L	synaptonemal complex central element protein 1-like	3981	0.21
chr8_129063151_129063374	0.39	ENSG00000221176	.	1864	0.37
chrX_149860118_149860300	0.39	MTMR1	myotubularin related protein 1	1226	0.6
chr8_41999804_41999957	0.39	RP11-589C21.5		10401	0.17
chr4_68425690_68425841	0.39	STAP1	signal transducing adaptor family member 1	1319	0.49
chrX_135053925_135054076	0.39	MMGT1	membrane magnesium transporter 1	2106	0.31
chr8_10189818_10189969	0.39	MSRA	methionine sulfoxide reductase A	30848	0.21
chr18_77173067_77173218	0.39	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	12750	0.24
chr12_15109847_15109998	0.39	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	4278	0.19
chr6_52151332_52151486	0.39	MCM3	minichromosome maintenance complex component 3	1774	0.39
chr3_18820139_18820372	0.39	ENSG00000228956	.	33019	0.25
chr1_36885062_36885213	0.39	ENSG00000201448	.	958	0.42
chr11_60873950_60874231	0.39	CD5	CD5 molecule	4109	0.21
chr15_60267965_60268474	0.39	FOXB1	forkhead box B1	28202	0.25
chr8_19558054_19558332	0.39	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	17921	0.28
chr11_14099941_14100092	0.38	ENSG00000212365	.	56516	0.16
chr11_128169809_128169960	0.38	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	205405	0.03
chr17_14098435_14098657	0.38	AC005224.2		15259	0.19
chr5_156652592_156652883	0.38	CTB-4E7.1		1347	0.34
chr11_35220930_35221081	0.38	CD44	CD44 molecule (Indian blood group)	1625	0.33
chr6_44969408_44969559	0.38	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	46236	0.2
chr13_26449514_26449665	0.38	AL138815.2	Uncharacterized protein	3090	0.27
chr3_16329108_16329574	0.38	OXNAD1	oxidoreductase NAD-binding domain containing 1	18593	0.15
chr5_118654684_118654873	0.38	ENSG00000243333	.	12452	0.19
chr1_14058081_14058259	0.38	PRDM2	PR domain containing 2, with ZNF domain	17728	0.21
chr6_90813480_90813638	0.38	ENSG00000222078	.	102334	0.07
chr10_22933738_22933949	0.38	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	53201	0.16
chr21_36417555_36417706	0.38	RUNX1	runt-related transcription factor 1	3832	0.38
chr12_68025335_68025706	0.38	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	16598	0.25
chrX_134518932_134519216	0.38	ZNF449	zinc finger protein 449	40353	0.13
chr2_7018212_7018651	0.38	RSAD2	radical S-adenosyl methionine domain containing 2	494	0.78
chr15_44958213_44958403	0.38	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	2375	0.21
chr13_99876727_99876878	0.38	ENSG00000201793	.	18840	0.17
chr1_111208863_111209034	0.38	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	8707	0.18
chr8_22389811_22389962	0.38	RP11-582J16.4		13032	0.11
chr1_169672704_169673057	0.38	SELL	selectin L	7959	0.2
chr6_167470073_167470306	0.38	CCR6	chemokine (C-C motif) receptor 6	55106	0.09
chr10_111840656_111840849	0.37	ADD3	adducin 3 (gamma)	73030	0.1
chr17_33857619_33857982	0.37	SLFN12L	schlafen family member 12-like	7080	0.12
chr1_101706352_101706538	0.37	RP4-575N6.5		2269	0.24
chr12_39725210_39725597	0.37	KIF21A	kinesin family member 21A	726	0.8
chr1_9717829_9718205	0.37	C1orf200	chromosome 1 open reading frame 200	3373	0.21
chr10_6597209_6597469	0.37	PRKCQ	protein kinase C, theta	24862	0.26
chr5_66512764_66513039	0.37	CD180	CD180 molecule	20274	0.26
chr8_128505801_128505952	0.37	CASC8	cancer susceptibility candidate 8 (non-protein coding)	11492	0.29
chr6_130544442_130544610	0.37	SAMD3	sterile alpha motif domain containing 3	427	0.9
chr2_28845314_28845495	0.37	PLB1	phospholipase B1	8049	0.21
chr1_180397322_180397473	0.37	ENSG00000265435	.	10128	0.24
chr4_154730657_154731010	0.37	SFRP2	secreted frizzled-related protein 2	20561	0.19
chrX_78618581_78618732	0.37	ITM2A	integral membrane protein 2A	4200	0.37
chr3_176825153_176825340	0.37	ENSG00000201343	.	13342	0.21
chr8_131017510_131017704	0.37	ENSG00000253043	.	760	0.61
chr6_16483008_16483237	0.37	ENSG00000265642	.	54368	0.17
chr6_144676059_144676210	0.37	UTRN	utrophin	10897	0.25
chr6_112069480_112069631	0.36	FYN	FYN oncogene related to SRC, FGR, YES	10762	0.26
chr3_111265770_111265929	0.36	CD96	CD96 molecule	4852	0.28
chr5_96267886_96268086	0.36	LNPEP	leucyl/cystinyl aminopeptidase	3182	0.23
chr15_44852872_44853058	0.36	RP11-151N17.1		2938	0.2
chr4_83282407_83282629	0.36	HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	1726	0.36
chr1_100917053_100917204	0.36	RP5-837M10.4		34425	0.17
chr19_19726701_19727139	0.36	PBX4	pre-B-cell leukemia homeobox 4	2805	0.16
chr1_52888786_52889059	0.36	ZCCHC11	zinc finger, CCHC domain containing 11	7831	0.14
chr2_103007589_103007741	0.36	IL18RAP	interleukin 18 receptor accessory protein	27484	0.12
chr9_74291840_74291991	0.36	TMEM2	transmembrane protein 2	27933	0.26
chr1_192484853_192485075	0.36	ENSG00000221145	.	24614	0.2
chr10_11223388_11223701	0.36	RP3-323N1.2		10205	0.22

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.7	GO:0010459	negative regulation of heart rate(GO:0010459)
0.2	0.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.8	GO:0002517	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.2	0.5	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.4	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.4	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.9	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.4	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.5	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.8	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.3	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.3	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.5	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.3	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.2	GO:0051497	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	1.0	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	4.8	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.1	0.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	0.5	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.1	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.3	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1	0.3	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.2	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.2	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.2	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.1	0.1	GO:0002507	tolerance induction(GO:0002507)
0.1	0.9	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.2	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.2	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1	0.3	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.1	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.2	GO:0042267	natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.1	0.1	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.5	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.1	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.1	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.5	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.2	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.4	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.5	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0033079	immature T cell proliferation(GO:0033079) immature T cell proliferation in thymus(GO:0033080) regulation of immature T cell proliferation(GO:0033083) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.2	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0045916	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.4	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0034776	response to histamine(GO:0034776)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.4	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0036260	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.3	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.5	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.2	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0032109	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0042428	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.8	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.3	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0042094	interleukin-2 biosynthetic process(GO:0042094)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.2	GO:0042992	negative regulation of transcription factor import into nucleus(GO:0042992)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.3	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.6	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:2000257	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0	0.3	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.4	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.0	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.3	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.4	GO:0048255	RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0	0.0	GO:0045117	azole transport(GO:0045117)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.4	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.1	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.0	0.3	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.0	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.3	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.1	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.2	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.7	GO:0006885	regulation of pH(GO:0006885)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.2	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.6	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.2	GO:0045010	actin nucleation(GO:0045010)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0051095	regulation of helicase activity(GO:0051095)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:0043011	myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0	0.0	GO:2000401	T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.0	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0015872	dopamine transport(GO:0015872)
0.0	0.0	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.4	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.5	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.2	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.0	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0031065	regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0	0.0	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.3	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.3	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.1	GO:0032392	DNA geometric change(GO:0032392)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	1.3	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0001840	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0032727	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.7	GO:1902403	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.4	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.1	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.2	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.2	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.3	GO:0007260	tyrosine phosphorylation of STAT protein(GO:0007260)
0.0	0.0	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0032722	positive regulation of chemokine production(GO:0032722)
0.0	0.2	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:1903831	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) response to ammonium ion(GO:0060359) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.0	GO:0051132	natural killer cell proliferation(GO:0001787) NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.2	GO:0071554	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0070234	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.0	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.5	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0043266	regulation of potassium ion transport(GO:0043266)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.2	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.6	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.3	GO:0007270	neuron-neuron synaptic transmission(GO:0007270)
0.0	0.0	GO:0048937	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.0	0.1	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.2	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	2.1	GO:0008380	RNA splicing(GO:0008380)
0.0	0.2	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.5	GO:0031424	keratinization(GO:0031424)
0.0	0.0	GO:0002429	immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.1	GO:2000117	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.0	GO:0032418	lysosome localization(GO:0032418)
0.0	0.0	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.5	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.2	GO:0000805	X chromosome(GO:0000805) Barr body(GO:0001740)
0.1	2.0	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	1.0	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	1.0	GO:0001772	immunological synapse(GO:0001772)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.3	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.2	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.1	0.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.4	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.4	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.6	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.5	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	1.0	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	2.4	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.8	GO:0055037	recycling endosome(GO:0055037)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.6	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.0	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.6	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.3	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0016604	nuclear body(GO:0016604)
0.0	0.5	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	0.6	GO:0033691	sialic acid binding(GO:0033691)
0.2	0.9	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.4	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	1.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	0.7	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.4	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	1.7	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.4	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1	0.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0004802	transketolase activity(GO:0004802)
0.1	0.7	GO:0051018	protein kinase A binding(GO:0051018)
0.1	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.1	GO:0001846	opsonin binding(GO:0001846)
0.1	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.5	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	1.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	2.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.0	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.4	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	1.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	1.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.5	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	1.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	1.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.3	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.6	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.1	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.9	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.5	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.6	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.3	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.3	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.2	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.0	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	1.0	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	4.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	1.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	2.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.8	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	1.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	3.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	2.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.3	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.8	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.0	0.2	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.5	REACTOME DEFENSINS	Genes involved in Defensins
0.0	1.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI

Results for BBX

Z-value: 2.09

Motif logo

Transcription factors associated with BBX

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the BBX motif across conditions

Conditions sorted by the z-value of the BBX motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: