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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.41

Motif logo

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol	Gene ID	Gene Info
BHLHE22 Ensembl NCBI GeneCards UniProt	ENSG00000180828.1	basic helix-loop-helix family member e22
BHLHA15 Ensembl NCBI GeneCards UniProt	ENSG00000180535.3	basic helix-loop-helix family member a15
BHLHE23 Ensembl NCBI GeneCards UniProt	ENSG00000125533.4	basic helix-loop-helix family member e23

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_97832727_97832878	BHLHA15	7937	0.215550	0.86	2.9e-03	Click!
chr7_97823901_97824052	BHLHA15	16763	0.198458	-0.78	1.4e-02	Click!
chr7_97833542_97833693	BHLHA15	7122	0.218503	0.71	3.3e-02	Click!
chr7_97841706_97841857	BHLHA15	215	0.943410	0.69	3.9e-02	Click!
chr7_97841199_97841386	BHLHA15	274	0.922153	0.68	4.5e-02	Click!
chr8_65492488_65492639	BHLHE22	251	0.922018	0.75	2.1e-02	Click!
chr8_65491896_65492047	BHLHE22	843	0.627445	0.60	8.5e-02	Click!
chr8_65492231_65492382	BHLHE22	508	0.800335	0.51	1.6e-01	Click!
chr8_65492689_65493120	BHLHE22	90	0.966376	0.37	3.2e-01	Click!
chr8_65493383_65493608	BHLHE22	681	0.557578	0.10	7.9e-01	Click!
chr20_61641366_61641627	BHLHE23	3109	0.240982	0.96	3.6e-05	Click!
chr20_61664968_61665122	BHLHE23	26658	0.152866	0.88	1.6e-03	Click!
chr20_61640655_61640982	BHLHE23	2431	0.275524	0.88	1.7e-03	Click!
chr20_61639034_61639185	BHLHE23	722	0.665435	0.85	4.1e-03	Click!
chr20_61641003_61641255	BHLHE23	2742	0.256967	0.83	5.7e-03	Click!

Activity of the BHLHE22_BHLHA15_BHLHE23 motif across conditions

Conditions sorted by the z-value of the BHLHE22_BHLHA15_BHLHE23 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_9138547_9138816	1.06	ANKRD12	ankyrin repeat domain 12	1120	0.41
chr2_204596118_204596345	1.05	CD28	CD28 molecule	24815	0.19
chr11_118077369_118077529	0.94	AMICA1	adhesion molecule, interacts with CXADR antigen 1	6151	0.15
chr11_122714029_122714331	0.93	CRTAM	cytotoxic and regulatory T cell molecule	4972	0.24
chr5_112714542_112714835	0.89	CTD-2201G3.1		54587	0.13
chr5_39180395_39180675	0.88	FYB	FYN binding protein	22594	0.24
chr12_65580659_65580810	0.87	LEMD3	LEM domain containing 3	17383	0.22
chrX_135716966_135717135	0.87	ENSG00000233093	.	4652	0.19
chr15_89171412_89171610	0.85	AEN	apoptosis enhancing nuclease	6910	0.15
chr4_25180038_25180189	0.85	PI4K2B	phosphatidylinositol 4-kinase type 2 beta	17828	0.21
chr7_2739159_2739434	0.84	AMZ1	archaelysin family metallopeptidase 1	11460	0.21
chr4_122087231_122087498	0.82	TNIP3	TNFAIP3 interacting protein 3	1869	0.39
chr5_130591714_130592070	0.82	CDC42SE2	CDC42 small effector 2	7810	0.29
chr10_14593831_14594082	0.82	FAM107B	family with sequence similarity 107, member B	2272	0.38
chr19_30171015_30171166	0.81	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	13309	0.22
chr11_117817862_117818245	0.80	TMPRSS13	transmembrane protease, serine 13	17879	0.16
chr4_154451016_154451207	0.80	KIAA0922	KIAA0922	25937	0.22
chr2_38922107_38922258	0.80	GALM	galactose mutarotase (aldose 1-epimerase)	13745	0.16
chr17_32295696_32295847	0.79	RP11-17M24.2		7779	0.22
chr22_29218726_29218929	0.79	CTA-292E10.6		4508	0.17
chr12_120453351_120453618	0.79	CCDC64	coiled-coil domain containing 64	25811	0.16
chr14_69239418_69239609	0.79	ZFP36L1	ZFP36 ring finger protein-like 1	18447	0.2
chr2_7051065_7051216	0.78	RNF144A	ring finger protein 144A	6383	0.19
chr21_19154654_19154891	0.78	AL109761.5		11033	0.23
chr1_175180888_175181276	0.78	KIAA0040	KIAA0040	19003	0.24
chr13_52396330_52396557	0.77	RP11-327P2.5		18010	0.18
chr1_90124246_90124415	0.77	LRRC8C	leucine rich repeat containing 8 family, member C	25699	0.15
chr9_101855388_101855572	0.76	TGFBR1	transforming growth factor, beta receptor 1	10840	0.23
chr8_27958288_27958439	0.76	ELP3	elongator acetyltransferase complex subunit 3	7399	0.22
chr5_14812908_14813128	0.76	ENSG00000264792	.	13103	0.24
chr1_169014315_169014663	0.76	ENSG00000252987	.	22013	0.19
chr17_79420586_79420890	0.75	ENSG00000266189	.	2524	0.16
chr2_44216786_44216937	0.75	LRPPRC	leucine-rich pentatricopeptide repeat containing	6254	0.27
chr12_92434816_92435054	0.75	C12orf79	chromosome 12 open reading frame 79	95862	0.08
chr11_73726348_73726623	0.74	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	6005	0.17
chr18_56487657_56487808	0.74	ENSG00000199713	.	1484	0.35
chr2_84880658_84880809	0.74	DNAH6	dynein, axonemal, heavy chain 6	4698	0.32
chr7_150268112_150268308	0.74	GIMAP4	GTPase, IMAP family member 4	3686	0.24
chr3_31549610_31550078	0.74	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	24438	0.26
chr11_128496756_128496907	0.74	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	39378	0.15
chr5_54284202_54284433	0.74	ESM1	endothelial cell-specific molecule 1	2826	0.22
chr16_68403491_68403775	0.73	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	1275	0.35
chr12_46659554_46659740	0.73	SLC38A1	solute carrier family 38, member 1	1837	0.48
chr15_42498763_42498914	0.73	VPS39	vacuolar protein sorting 39 homolog (S. cerevisiae)	1513	0.26
chr5_156731351_156731502	0.72	CYFIP2	cytoplasmic FMR1 interacting protein 2	6619	0.17
chr1_9006386_9006537	0.72	CA6	carbonic anhydrase VI	515	0.76
chr3_150917333_150917570	0.72	GPR171	G protein-coupled receptor 171	3528	0.19
chr4_38511957_38512205	0.71	RP11-617D20.1		114115	0.06
chr4_100429542_100429693	0.70	C4orf17	chromosome 4 open reading frame 17	2544	0.3
chr17_8858889_8859261	0.70	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	9949	0.24
chr4_40216724_40216947	0.69	RHOH	ras homolog family member H	14871	0.21
chr14_101106211_101106459	0.69	CTD-2644I21.1		50672	0.08
chr4_39028874_39029217	0.68	TMEM156	transmembrane protein 156	4996	0.23
chr8_19558054_19558332	0.68	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	17921	0.28
chr2_36468391_36468542	0.68	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	114603	0.07
chr1_101573969_101574120	0.67	ENSG00000252765	.	24665	0.17
chr11_128189476_128189730	0.67	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	185686	0.03
chr11_104787758_104787909	0.67	RP11-693N9.2		7191	0.2
chr15_92403831_92404063	0.67	SLCO3A1	solute carrier organic anion transporter family, member 3A1	6596	0.27
chr2_207025046_207025348	0.67	EEF1B2	eukaryotic translation elongation factor 1 beta 2	866	0.28
chr12_113523386_113523537	0.67	DTX1	deltex homolog 1 (Drosophila)	27966	0.13
chr2_182380538_182380689	0.67	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	58458	0.15
chr10_111783916_111784067	0.67	ADD3	adducin 3 (gamma)	16269	0.2
chr5_52034605_52034756	0.66	ITGA1	integrin, alpha 1	49050	0.14
chrX_15135310_15135461	0.66	ASB9	ankyrin repeat and SOCS box containing 9	137502	0.05
chr15_63448861_63449086	0.66	RPS27L	ribosomal protein S27-like	0	0.98
chr11_81580427_81580763	0.66	ENSG00000264110	.	21283	0.3
chr15_89447421_89447572	0.66	HAPLN3	hyaluronan and proteoglycan link protein 3	8639	0.18
chr1_168500435_168500586	0.66	XCL2	chemokine (C motif) ligand 2	12725	0.24
chr2_182007943_182008229	0.66	UBE2E3	ubiquitin-conjugating enzyme E2E 3	161336	0.04
chr17_11959403_11959554	0.65	ENSG00000252707	.	19524	0.17
chr21_37671483_37671700	0.65	MORC3	MORC family CW-type zinc finger 3	20896	0.14
chr2_20540429_20540580	0.65	PUM2	pumilio RNA-binding family member 2	9878	0.18
chr7_12770799_12771102	0.65	ENSG00000199470	.	30436	0.2
chr1_54842092_54842291	0.65	SSBP3	single stranded DNA binding protein 3	28986	0.18
chr9_92079649_92079925	0.65	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	8919	0.24
chr1_29259178_29259329	0.65	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	18162	0.17
chr14_62164886_62165037	0.64	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	621	0.79
chr6_167469634_167469960	0.64	CCR6	chemokine (C-C motif) receptor 6	55498	0.09
chr17_65450648_65450799	0.64	ENSG00000244610	.	2683	0.2
chr1_211526157_211526486	0.64	TRAF5	TNF receptor-associated factor 5	6615	0.27
chr6_108140441_108140592	0.64	SCML4	sex comb on midleg-like 4 (Drosophila)	5000	0.3
chr10_13828697_13828885	0.64	RP11-353M9.1		57408	0.1
chr5_140977229_140977602	0.63	DIAPH1	diaphanous-related formin 1	10363	0.11
chr1_62246804_62246985	0.63	ENSG00000200575	.	35197	0.16
chr14_65391601_65391789	0.63	CHURC1-FNTB	CHURC1-FNTB readthrough	941	0.31
chr14_91879240_91879633	0.63	CCDC88C	coiled-coil domain containing 88C	4254	0.28
chr1_90218642_90218793	0.63	ENSG00000239176	.	15160	0.2
chr6_131534768_131534919	0.63	AKAP7	A kinase (PRKA) anchor protein 7	12876	0.3
chr7_13950498_13950649	0.63	ETV1	ets variant 1	75493	0.12
chr21_34671594_34671818	0.63	IFNAR1	interferon (alpha, beta and omega) receptor 1	25028	0.13
chr3_107795044_107795195	0.63	CD47	CD47 molecule	14742	0.29
chr17_63178187_63178462	0.62	RGS9	regulator of G-protein signaling 9	44732	0.17
chr5_130587781_130588081	0.62	CDC42SE2	CDC42 small effector 2	11771	0.27
chr1_12219122_12219314	0.61	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	7842	0.16
chr5_39156527_39156873	0.61	FYB	FYN binding protein	46429	0.15
chr5_130623955_130624205	0.61	CDC42SE2	CDC42 small effector 2	24287	0.25
chr11_117685399_117685646	0.61	DSCAML1	Down syndrome cell adhesion molecule like 1	2718	0.19
chr9_77801736_77801887	0.61	ENSG00000200041	.	5274	0.23
chr8_68591514_68591665	0.61	ENSG00000221660	.	32278	0.19
chr1_222472325_222472476	0.61	ENSG00000222399	.	204677	0.02
chr8_101508482_101508638	0.61	KB-1615E4.3		3804	0.22
chr10_8178297_8178448	0.60	GATA3	GATA binding protein 3	81603	0.11
chr10_71380293_71380444	0.60	C10orf35	chromosome 10 open reading frame 35	9646	0.2
chr8_67987425_67987576	0.60	CSPP1	centrosome and spindle pole associated protein 1	8583	0.15
chr7_50436926_50437104	0.60	ENSG00000200815	.	66063	0.11
chr8_128505492_128505643	0.60	CASC8	cancer susceptibility candidate 8 (non-protein coding)	11183	0.29
chr3_186768542_186768811	0.60	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	7145	0.25
chr2_172748432_172748583	0.60	SLC25A12	solute carrier family 25 (aspartate/glutamate carrier), member 12	2226	0.32
chr2_198904603_198904754	0.60	PLCL1	phospholipase C-like 1	43858	0.21
chr9_351038_351189	0.59	DOCK8	dedicator of cytokinesis 8	15116	0.22
chr17_46048804_46049029	0.59	CDK5RAP3	CDK5 regulatory subunit associated protein 3	399	0.71
chr21_34609127_34609397	0.59	IFNAR2	interferon (alpha, beta and omega) receptor 2	6548	0.15
chr3_112678927_112679101	0.59	CD200R1	CD200 receptor 1	14745	0.16
chr12_66708664_66708815	0.59	HELB	helicase (DNA) B	12414	0.17
chr2_36203182_36203333	0.59	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	379812	0.01
chr2_198159587_198159997	0.58	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	7451	0.18
chr7_158987108_158987259	0.58	VIPR2	vasoactive intestinal peptide receptor 2	49534	0.19
chr15_88226016_88226167	0.58	ENSG00000207150	.	208571	0.03
chr5_49931104_49931309	0.58	PARP8	poly (ADP-ribose) polymerase family, member 8	30527	0.26
chrX_49144105_49144462	0.58	PPP1R3F	protein phosphatase 1, regulatory subunit 3F	7044	0.09
chr13_30508561_30508712	0.58	LINC00572	long intergenic non-protein coding RNA 572	7848	0.3
chr7_86782710_86782894	0.58	DMTF1	cyclin D binding myb-like transcription factor 1	855	0.46
chr12_15714705_15714919	0.58	PTPRO	protein tyrosine phosphatase, receptor type, O	15526	0.27
chr21_16056596_16056882	0.57	AF165138.7	Protein LOC388813	25597	0.23
chr1_108383656_108383813	0.57	ENSG00000265536	.	64856	0.13
chr3_56924360_56924511	0.57	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	26064	0.21
chr13_74626995_74627156	0.57	KLF12	Kruppel-like factor 12	57889	0.17
chr2_33197_33348	0.57	FAM110C	family with sequence similarity 110, member C	13113	0.3
chr6_139435628_139435860	0.57	HECA	headcase homolog (Drosophila)	20505	0.23
chr7_76365532_76365683	0.57	ENSG00000221249	.	38636	0.18
chr8_129061178_129061597	0.57	ENSG00000221176	.	11	0.98
chr6_135408458_135409018	0.57	HBS1L	HBS1-like (S. cerevisiae)	15456	0.2
chr6_138028568_138028824	0.57	ENSG00000216097	.	9389	0.27
chr1_92783230_92783381	0.57	GLMN	glomulin, FKBP associated protein	18761	0.18
chr12_4333346_4333506	0.57	CCND2	cyclin D2	49512	0.12
chr17_40609661_40609821	0.56	ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1	1121	0.32
chr12_133078554_133078840	0.56	FBRSL1	fibrosin-like 1	11540	0.2
chr17_70927920_70928132	0.56	SLC39A11	solute carrier family 39, member 11	61046	0.13
chr7_92311846_92312026	0.56	ENSG00000206763	.	19192	0.23
chr8_61706063_61706431	0.56	RP11-33I11.2		15918	0.26
chr10_81308671_81308822	0.56	SFTPA2	surfactant protein A2	10844	0.18
chr2_106710162_106710313	0.56	C2orf40	chromosome 2 open reading frame 40	27981	0.2
chr2_241630055_241630206	0.56	AQP12A	aquaporin 12A	1132	0.41
chr1_171463542_171463693	0.55	ENSG00000239373	.	2067	0.26
chr14_22564266_22564545	0.55	ENSG00000238634	.	46482	0.18
chr4_87970286_87970614	0.55	AFF1	AF4/FMR2 family, member 1	354	0.92
chr10_116304728_116305249	0.55	ABLIM1	actin binding LIM protein 1	18298	0.25
chr1_150997331_150997482	0.55	PRUNE	prune exopolyphosphatase	188	0.86
chr12_52549851_52550322	0.55	KRT80	keratin 80	35698	0.09
chr12_50676604_50676836	0.55	LIMA1	LIM domain and actin binding 1	547	0.7
chr7_29284217_29284368	0.55	AC004593.3		35706	0.16
chr8_129557413_129557564	0.55	ENSG00000221351	.	274552	0.01
chr6_41947626_41947787	0.55	CCND3	cyclin D3	38120	0.1
chr6_154544577_154544728	0.55	IPCEF1	interaction protein for cytohesin exchange factors 1	23338	0.27
chr6_149814086_149814315	0.55	ZC3H12D	zinc finger CCCH-type containing 12D	8003	0.16
chr1_199058768_199058956	0.55	ENSG00000239006	.	107450	0.08
chr9_20555069_20555220	0.55	ENSG00000252324	.	21072	0.2
chr6_170747583_170747755	0.55	RP1-140C12.2		24442	0.21
chr20_39775784_39776022	0.55	RP1-1J6.2		9260	0.2
chr14_32414093_32414244	0.55	RP11-187E13.1	Uncharacterized protein	109	0.98
chr3_107801472_107801678	0.54	CD47	CD47 molecule	8286	0.31
chr15_29278217_29278368	0.54	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2	4330	0.26
chr18_60980260_60980411	0.54	RP11-28F1.2		980	0.53
chr2_95740104_95740281	0.54	AC103563.9		21271	0.15
chr1_221880023_221880330	0.54	DUSP10	dual specificity phosphatase 10	30626	0.25
chr6_149416803_149417130	0.54	RP11-162J8.3		63257	0.12
chr4_57629328_57629479	0.54	ENSG00000240545	.	31405	0.14
chr7_21478139_21478290	0.54	SP4	Sp4 transcription factor	10553	0.19
chr20_20529368_20529556	0.54	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	36218	0.22
chr22_29351533_29351684	0.54	ZNRF3	zinc and ring finger 3	31432	0.14
chr16_68103802_68103968	0.54	ENSG00000221789	.	14098	0.09
chr8_42213683_42213940	0.54	POLB	polymerase (DNA directed), beta	881	0.57
chr4_6677676_6678140	0.53	AC093323.1	Uncharacterized protein	16281	0.14
chr12_779017_779174	0.53	NINJ2	ninjurin 2	6150	0.2
chr18_77131479_77131632	0.53	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	24301	0.18
chrX_106230754_106231110	0.53	MORC4	MORC family CW-type zinc finger 4	5638	0.26
chr16_67586263_67586449	0.53	FAM65A	family with sequence similarity 65, member A	8059	0.09
chr1_65475101_65475369	0.53	ENSG00000212257	.	13522	0.19
chr6_130509298_130509449	0.53	SAMD3	sterile alpha motif domain containing 3	27062	0.21
chr6_112167438_112167589	0.52	FYN	FYN oncogene related to SRC, FGR, YES	305	0.94
chr12_46624022_46624184	0.52	SLC38A1	solute carrier family 38, member 1	37381	0.22
chr2_120692302_120692453	0.52	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	2325	0.34
chr8_66894110_66894261	0.52	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	39610	0.2
chr19_5971655_5971871	0.52	RANBP3	RAN binding protein 3	6327	0.12
chr2_149281634_149282124	0.52	MBD5	methyl-CpG binding domain protein 5	55585	0.16
chr1_235404415_235404676	0.52	ARID4B	AT rich interactive domain 4B (RBP1-like)	27314	0.16
chr7_45077305_45077456	0.52	CCM2	cerebral cavernous malformation 2	10109	0.14
chr1_160634296_160634461	0.52	RP11-404F10.2		6190	0.17
chr20_15877051_15877202	0.52	MACROD2	MACRO domain containing 2	33676	0.25
chr6_158286807_158286958	0.52	RP11-52J3.2		9360	0.17
chr1_200832323_200832474	0.52	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2	7176	0.19
chr8_59929731_59929882	0.52	RP11-328K2.1		24309	0.23
chr3_43062065_43062216	0.52	FAM198A	family with sequence similarity 198, member A	41100	0.14
chr9_112723853_112724004	0.52	AKAP2	A kinase (PRKA) anchor protein 2	86950	0.09
chrX_13106601_13106839	0.51	FAM9C	family with sequence similarity 9, member C	43919	0.18
chr15_61014407_61014558	0.51	ENSG00000212625	.	14486	0.21
chr6_35557441_35557592	0.51	ENSG00000212579	.	62079	0.09
chr8_123652385_123652536	0.51	ENSG00000238901	.	31070	0.23
chr7_87719922_87720201	0.51	ADAM22	ADAM metallopeptidase domain 22	72285	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.3	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.5	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.3	GO:1904019	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.1	0.4	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.2	GO:0014055	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1	0.3	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1	0.3	GO:0060017	parathyroid gland development(GO:0060017)
0.1	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0060009	Sertoli cell development(GO:0060009)
0.1	0.3	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.2	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.2	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.1	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.4	GO:0043248	proteasome assembly(GO:0043248)
0.1	0.4	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.9	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.4	GO:0031529	ruffle organization(GO:0031529)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	1.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.3	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.4	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.2	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0071637	monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.4	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.2	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.4	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.3	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.3	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0030540	female genitalia development(GO:0030540)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.5	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.2	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0072178	nephric duct morphogenesis(GO:0072178) mesonephric duct morphogenesis(GO:0072180)
0.0	0.3	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0032817	regulation of natural killer cell proliferation(GO:0032817)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:0030811	regulation of nucleotide catabolic process(GO:0030811)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.5	GO:0006612	protein targeting to membrane(GO:0006612)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	1.0	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0031935	regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.3	GO:0007530	sex determination(GO:0007530)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0045621	positive regulation of lymphocyte differentiation(GO:0045621)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.7	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.3	GO:0048255	RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0	0.0	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0072170	metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	1.0	GO:0050870	positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	0.2	GO:0048041	cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0	0.0	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.1	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.0	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.1	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0006413	translational initiation(GO:0006413)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.4	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0044252	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0060603	mammary gland duct morphogenesis(GO:0060603)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.0	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.3	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	1.0	GO:0006417	regulation of translation(GO:0006417)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.5	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.5	GO:0030897	HOPS complex(GO:0030897)
0.0	0.3	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.3	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.5	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.5	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.5	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.7	GO:0000502	proteasome complex(GO:0000502)
0.0	1.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:0031970	organelle envelope lumen(GO:0031970)
0.0	0.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.0	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.4	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.5	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.6	GO:0008494	translation activator activity(GO:0008494)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.1	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.2	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.3	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.4	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	1.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	1.0	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.3	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.3	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.0	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.3	GO:0035586	G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) purinergic receptor activity(GO:0035586) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.8	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.8	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	1.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.0	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation

Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.41

Motif logo

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the BHLHE22_BHLHA15_BHLHE23 motif across conditions

Conditions sorted by the z-value of the BHLHE22_BHLHA15_BHLHE23 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: