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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for BHLHE40

Z-value: 1.28

Motif logo

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Transcription factors associated with BHLHE40

Gene Symbol Gene ID Gene Info
BHLHE40
ENSG00000134107.4 basic helix-loop-helix family member e40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_4991634_4991797BHLHE40290860.162405-0.531.4e-01Click!
chr3_5020639_5020790BHLHE40870.9417730.511.6e-01Click!
chr3_4994783_4994934BHLHE40259430.169522-0.491.8e-01Click!
chr3_5019096_5019422BHLHE4015420.3746890.412.7e-01Click!
chr3_5018310_5018816BHLHE4022380.2974690.373.3e-01Click!

Activity of the BHLHE40 motif across conditions

Conditions sorted by the z-value of the BHLHE40 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_157548637_157548975 2.10 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 78761
 0.11
chr6_157548368_157548619 1.30 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 78448
 0.11
chr6_150401228_150401379 0.68 ULBP3
 UL16 binding protein 3
 11072
 0.18
chr11_95393873_95394024 0.49 FAM76B
 family with sequence similarity 76, member B
 126021
 0.05
chr4_40303302_40303674 0.45 CHRNA9
 cholinergic receptor, nicotinic, alpha 9 (neuronal)
 33858
 0.17
chr1_209944656_209944807 0.44 TRAF3IP3
 TRAF3 interacting protein 3
 2771
 0.19
chr7_2070925_2071076 0.44 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 48648
 0.17
chr9_92138368_92138605 0.42 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 25441
 0.19
chr11_118178245_118178503 0.42 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
 2760
 0.18
chr2_106604937_106605088 0.42 C2orf40
 chromosome 2 open reading frame 40
 74738
 0.11
chr15_93579130_93579323 0.42 CHD2
 chromodomain helicase DNA binding protein 2
 27130
 0.2
chr20_57973693_57973970 0.42 ENSG00000263903
 .
 52296
 0.16
chr1_42271419_42271644 0.41 ENSG00000264896
 .
 46719
 0.18
chr2_149284716_149284924 0.40 MBD5
 methyl-CpG binding domain protein 5
 58526
 0.15
chr1_2950991_2951142 0.40 ACTRT2
 actin-related protein T2
 13020
 0.19
chr9_92105986_92106169 0.40 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 6270
 0.24
chr3_46416627_46416863 0.40 CCR5
 chemokine (C-C motif) receptor 5 (gene/pseudogene)
 2584
 0.23
chr6_71360263_71360634 0.39 SMAP1
 small ArfGAP 1
 17031
 0.26
chr3_128032806_128032957 0.39 ENSG00000221067
 .
 48127
 0.15
chr7_150639030_150639181 0.38 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 13889
 0.15
chr2_169290603_169290754 0.38 ENSG00000239230
 .
 7037
 0.21
chr12_58153080_58153231 0.38 MARCH9
 membrane-associated ring finger (C3HC4) 9
 1885
 0.12
chr12_25432795_25432959 0.38 KRAS
 Kirsten rat sarcoma viral oncogene homolog
 29007
 0.18
chr20_50720819_50720982 0.37 ZFP64
 ZFP64 zinc finger protein
 489
 0.89
chr1_241839762_241839978 0.37 WDR64
 WD repeat domain 64
 7012
 0.22
chr1_235377409_235377560 0.37 ARID4B
 AT rich interactive domain 4B (RBP1-like)
 253
 0.92
chr7_1085411_1085702 0.37 GPR146
 G protein-coupled receptor 146
 1344
 0.26
chr14_100540531_100540793 0.36 CTD-2376I20.1
553
 0.71
chr7_139924008_139924237 0.36 ENSG00000199971
 .
 14651
 0.16
chr11_748009_748200 0.35 TALDO1
 transaldolase 1
 676
 0.44
chr15_44958521_44958824 0.35 PATL2
 protein associated with topoisomerase II homolog 2 (yeast)
 2011
 0.24
chr13_43563311_43563462 0.35 EPSTI1
 epithelial stromal interaction 1 (breast)
 1981
 0.43
chr2_113943965_113944116 0.35 PSD4
 pleckstrin and Sec7 domain containing 4
 9817
 0.14
chr9_123641457_123641690 0.35 PHF19
 PHD finger protein 19
 1967
 0.31
chr16_89850957_89851182 0.34 FANCA
 Fanconi anemia, complementation group A
 31974
 0.1
chr3_18416180_18416331 0.34 RP11-158G18.1
34872
 0.19
chr10_63810330_63810481 0.34 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 1435
 0.54
chr15_65075233_65075384 0.34 RBPMS2
 RNA binding protein with multiple splicing 2
 7522
 0.14
chr15_32635679_32635830 0.34 ENSG00000221444
 .
 49919
 0.09
chr1_101742974_101743225 0.34 RP4-575N6.5
34385
 0.14
chr19_16486076_16486459 0.34 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 13503
 0.14
chr7_50426987_50427896 0.33 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 60196
 0.13
chr5_131347971_131348122 0.33 ACSL6
 acyl-CoA synthetase long-chain family member 6
 176
 0.88
chr6_36487605_36487756 0.33 ENSG00000239964
 .
 2288
 0.23
chr1_194025907_194026313 0.33 ENSG00000252241
 .
 325036
 0.01
chrX_128889315_128889636 0.33 XPNPEP2
 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
 16477
 0.19
chr9_4605304_4605466 0.33 SLC1A1
 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
 33050
 0.16
chr16_57041025_57041193 0.33 NLRC5
 NLR family, CARD domain containing 5
 2711
 0.2
chr1_209944824_209944985 0.33 TRAF3IP3
 TRAF3 interacting protein 3
 2944
 0.19
chr17_38076794_38077078 0.32 GSDMB
 gasdermin B
 2033
 0.21
chr12_2799901_2800122 0.32 CACNA1C-AS1
 CACNA1C antisense RNA 1
 273
 0.91
chr3_33101505_33101658 0.32 GLB1
 galactosidase, beta 1
 36703
 0.13
chr12_92726454_92726695 0.32 RP11-693J15.4
88733
 0.08
chr1_12149159_12149332 0.32 ENSG00000201135
 .
 11204
 0.15
chr17_2699183_2699336 0.32 RAP1GAP2
 RAP1 GTPase activating protein 2
 473
 0.8
chr14_25162667_25162947 0.32 GZMB
 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
 59334
 0.11
chr17_18858474_18858633 0.32 AC090286.4
1091
 0.36
chr16_57634856_57635007 0.31 GPR56
 G protein-coupled receptor 56
 9633
 0.15
chr22_50754075_50754226 0.31 XX-C283C717.1
1090
 0.31
chr5_157940155_157940453 0.31 CTD-2363C16.1
469710
 0.01
chr9_135382524_135382903 0.31 BARHL1
 BarH-like homeobox 1
 74859
 0.09
chr11_64821935_64822086 0.31 NAALADL1
 N-acetylated alpha-linked acidic dipeptidase-like 1
 3983
 0.08
chr5_171543346_171543497 0.31 ENSG00000266671
 .
 35441
 0.16
chr1_112045793_112046152 0.31 ADORA3
 adenosine A3 receptor
 138
 0.93
chr7_132121999_132122205 0.31 AC011625.1
85009
 0.1
chr2_10815541_10815692 0.31 NOL10
 nucleolar protein 10
 3800
 0.22
chr7_158991213_158991434 0.31 VIPR2
 vasoactive intestinal peptide receptor 2
 53674
 0.18
chr12_131796444_131796595 0.31 ENSG00000212251
 .
 12223
 0.23
chr3_187692256_187692598 0.31 LPP
 LIM domain containing preferred translocation partner in lipoma
 178645
 0.03
chr10_11309961_11310112 0.30 CELF2-AS1
 CELF2 antisense RNA 1
 51811
 0.15
chr5_98267544_98267695 0.30 ENSG00000200351
 .
 4832
 0.23
chr3_45906834_45907101 0.30 CCR9
 chemokine (C-C motif) receptor 9
 21029
 0.15
chr2_198143456_198143859 0.30 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 23586
 0.16
chr20_62859464_62859615 0.30 PCMTD2
 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
 27555
 0.17
chr5_1313612_1313923 0.30 ENSG00000263670
 .
 4275
 0.2
chr1_20013079_20013230 0.30 HTR6
 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
 21374
 0.16
chr11_114053249_114053976 0.30 NNMT
 nicotinamide N-methyltransferase
 74941
 0.09
chr11_96024786_96024937 0.30 ENSG00000266192
 .
 49741
 0.14
chr17_73239171_73239322 0.30 GGA3
 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
 4084
 0.11
chr11_113955241_113955493 0.30 ENSG00000221112
 .
 2284
 0.34
chr18_21509698_21509962 0.30 LAMA3
 laminin, alpha 3
 1627
 0.41
chr14_98899836_98899987 0.30 ENSG00000241757
 .
 81910
 0.11
chr2_128399438_128399670 0.30 LIMS2
 LIM and senescent cell antigen-like domains 2
 152
 0.94
chr15_61135667_61135839 0.29 RP11-554D20.1
78814
 0.11
chr17_76745970_76746190 0.29 CYTH1
 cytohesin 1
 13108
 0.19
chr6_137710654_137710959 0.29 OLIG3
 oligodendrocyte transcription factor 3
 104725
 0.07
chr1_227949174_227949396 0.29 SNAP47
 synaptosomal-associated protein, 47kDa
 13521
 0.16
chr8_100024823_100024974 0.29 VPS13B
 vacuolar protein sorting 13 homolog B (yeast)
 596
 0.74
chr1_160645057_160645403 0.29 RP11-404F10.2
1918
 0.29
chr21_44252788_44252947 0.29 WDR4
 WD repeat domain 4
 46774
 0.13
chr5_133376557_133376708 0.29 VDAC1
 voltage-dependent anion channel 1
 35808
 0.17
chr19_42027703_42027944 0.29 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 28063
 0.13
chr2_106404052_106404457 0.29 NCK2
 NCK adaptor protein 2
 28761
 0.23
chr14_100537205_100537447 0.28 CTD-2376I20.1
3889
 0.18
chr12_133349779_133349930 0.28 ANKLE2
 ankyrin repeat and LEM domain containing 2
 11380
 0.15
chr2_662119_662318 0.28 TMEM18
 transmembrane protein 18
 13557
 0.2
chr8_27226083_27226368 0.28 PTK2B
 protein tyrosine kinase 2 beta
 11943
 0.22
chr1_229228666_229228817 0.28 RP5-1061H20.5
134568
 0.04
chr9_140165488_140165705 0.28 TOR4A
 torsin family 4, member A
 6605
 0.07
chr10_126849895_126850046 0.28 CTBP2
 C-terminal binding protein 2
 340
 0.93
chrX_46471596_46471846 0.28 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 38502
 0.17
chr1_54815665_54815816 0.28 SSBP3
 single stranded DNA binding protein 3
 55437
 0.11
chr13_114906998_114907153 0.28 RASA3
 RAS p21 protein activator 3
 8989
 0.22
chr8_66854346_66854497 0.27 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 79374
 0.1
chr17_78637163_78637475 0.27 RPTOR
 regulatory associated protein of MTOR, complex 1
 118051
 0.05
chr1_1107776_1107927 0.27 TTLL10
 tubulin tyrosine ligase-like family, member 10
 1432
 0.2
chr17_71826931_71827082 0.27 SDK2
 sidekick cell adhesion molecule 2
 186778
 0.03
chr14_22409773_22409924 0.27 ENSG00000222776
 .
 161063
 0.03
chr15_64151124_64151275 0.27 ENSG00000199156
 .
 12019
 0.21
chr16_27206515_27206666 0.27 KDM8
 lysine (K)-specific demethylase 8
 8217
 0.19
chr4_89202595_89202746 0.27 PPM1K
 protein phosphatase, Mg2+/Mn2+ dependent, 1K
 2372
 0.23
chr21_46496959_46497110 0.27 ADARB1
 adenosine deaminase, RNA-specific, B1
 2519
 0.22
chr20_47430608_47430759 0.27 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 13737
 0.26
chr14_61827530_61827767 0.27 PRKCH
 protein kinase C, eta
 144
 0.97
chr6_167524624_167524999 0.27 CCR6
 chemokine (C-C motif) receptor 6
 484
 0.81
chr13_99849164_99849315 0.27 UBAC2
 UBA domain containing 2
 3789
 0.23
chr16_85933118_85933269 0.27 IRF8
 interferon regulatory factor 8
 424
 0.87
chr14_105532821_105533069 0.27 GPR132
 G protein-coupled receptor 132
 1163
 0.49
chr7_2750642_2751031 0.27 AMZ1
 archaelysin family metallopeptidase 1
 23000
 0.18
chr2_3243298_3243449 0.27 TSSC1-IT1
 TSSC1 intronic transcript 1 (non-protein coding)
 61863
 0.13
chr5_56122812_56123396 0.27 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
 11703
 0.17
chr9_92450655_92450815 0.27 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 230782
 0.02
chr10_22969605_22969760 0.27 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 33355
 0.22
chr8_125685655_125685918 0.27 MTSS1
 metastasis suppressor 1
 54071
 0.13
chr21_32929274_32929425 0.27 TIAM1
 T-cell lymphoma invasion and metastasis 1
 1941
 0.32
chr10_8087441_8087780 0.27 GATA3
 GATA binding protein 3
 9046
 0.32
chr12_112545861_112546012 0.26 NAA25
 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
 611
 0.66
chr1_182599288_182599608 0.26 RGS16
 regulator of G-protein signaling 16
 25905
 0.17
chr6_157548074_157548363 0.26 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 78173
 0.11
chr19_15624982_15625133 0.26 CYP4F22
 cytochrome P450, family 4, subfamily F, polypeptide 22
 5753
 0.16
chr17_43307469_43307750 0.26 CTD-2020K17.1
8020
 0.1
chr3_128518442_128518718 0.26 RAB7A
 RAB7A, member RAS oncogene family
 4378
 0.21
chr2_106371801_106372035 0.26 NCK2
 NCK adaptor protein 2
 9730
 0.3
chr1_157693341_157693492 0.26 FCRL3
 Fc receptor-like 3
 22769
 0.17
chr3_171826118_171826452 0.26 FNDC3B
 fibronectin type III domain containing 3B
 18479
 0.26
chr20_62362374_62362787 0.26 LIME1
 Lck interacting transmembrane adaptor 1
 5055
 0.09
chr21_45502719_45503242 0.26 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 24191
 0.15
chr16_68389761_68390217 0.26 SMPD3
 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
 14919
 0.11
chr4_2816087_2816379 0.26 SH3BP2
 SH3-domain binding protein 2
 2202
 0.32
chr3_186760165_186760316 0.26 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 1291
 0.54
chr1_226039631_226039809 0.26 RP11-285F7.2
5497
 0.14
chr12_133014236_133014611 0.26 MUC8
 mucin 8
 36303
 0.16
chr20_57735532_57735874 0.26 ZNF831
 zinc finger protein 831
 30372
 0.2
chr1_42269178_42269372 0.26 ENSG00000264896
 .
 44463
 0.19
chr6_167460456_167460849 0.26 FGFR1OP
 FGFR1 oncogene partner
 47756
 0.1
chr8_144910846_144910997 0.26 PUF60
 poly-U binding splicing factor 60KDa
 275
 0.81
chr7_152039023_152039174 0.26 ENSG00000253088
 .
 60767
 0.12
chr16_17440476_17440787 0.26 XYLT1
 xylosyltransferase I
 124107
 0.06
chr15_76574850_76575217 0.26 ETFA
 electron-transfer-flavoprotein, alpha polypeptide
 9799
 0.23
chr20_60867419_60867570 0.25 ADRM1
 adhesion regulating molecule 1
 10567
 0.12
chr18_21551706_21552127 0.25 TTC39C
 tetratricopeptide repeat domain 39C
 20821
 0.16
chr10_126414122_126414344 0.25 FAM53B
 family with sequence similarity 53, member B
 17306
 0.16
chr21_43834242_43834420 0.25 ENSG00000252619
 .
 3371
 0.17
chr22_37641156_37641409 0.25 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 794
 0.57
chr13_100039907_100040178 0.25 ENSG00000207719
 .
 31657
 0.16
chr1_78354309_78354460 0.25 NEXN
 nexilin (F actin binding protein)
 37
 0.95
chr3_187719085_187719236 0.25 LPP
 LIM domain containing preferred translocation partner in lipoma
 151912
 0.04
chr11_76376085_76376254 0.25 LRRC32
 leucine rich repeat containing 32
 4875
 0.2
chr1_101711671_101711822 0.25 RP4-575N6.5
3032
 0.21
chr1_77884409_77884560 0.25 ENSG00000251767
 .
 1526
 0.44
chr13_110222272_110222771 0.25 LINC00676
 long intergenic non-protein coding RNA 676
 158108
 0.04
chr7_31064429_31064580 0.25 ADCYAP1R1
 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
 27572
 0.21
chr2_64553101_64553267 0.25 ENSG00000264297
 .
 14709
 0.25
chr13_114909698_114910252 0.25 RASA3
 RAS p21 protein activator 3
 11889
 0.21
chr1_200980853_200981004 0.25 KIF21B
 kinesin family member 21B
 11608
 0.18
chr3_38036912_38037201 0.25 VILL
 villin-like
 1412
 0.32
chr6_20206050_20206262 0.25 RP11-239H6.2
6162
 0.24
chr11_2489014_2489234 0.25 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 6007
 0.18
chr10_13932808_13933126 0.25 FRMD4A
 FERM domain containing 4A
 32055
 0.2
chr14_100610702_100610964 0.25 DEGS2
 delta(4)-desaturase, sphingolipid 2
 15099
 0.12
chr22_26690400_26690699 0.25 SEZ6L
 seizure related 6 homolog (mouse)-like
 2332
 0.34
chr7_92666364_92666515 0.25 ENSG00000266794
 .
 65826
 0.11
chr3_9992673_9992875 0.25 PRRT3
 proline-rich transmembrane protein 3
 1300
 0.22
chr15_34695379_34695530 0.25 GOLGA8A
 golgin A8 family, member A
 4434
 0.16
chr11_14076377_14076528 0.25 ENSG00000212365
 .
 80080
 0.11
chr4_100739674_100739989 0.25 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
 1828
 0.43
chr2_219233652_219233882 0.24 ENSG00000225062
 .
 1209
 0.27
chr16_50318201_50318668 0.24 ADCY7
 adenylate cyclase 7
 3388
 0.25
chr18_21547738_21547925 0.24 LAMA3
 laminin, alpha 3
 17974
 0.17
chr7_2138652_2138817 0.24 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 8609
 0.28
chr10_102107561_102107838 0.24 SCD
 stearoyl-CoA desaturase (delta-9-desaturase)
 818
 0.47
chr15_53075384_53075631 0.24 ONECUT1
 one cut homeobox 1
 2127
 0.43
chr1_167618740_167619238 0.24 RP3-455J7.4
19078
 0.18
chr1_19400551_19400797 0.24 UBR4
 ubiquitin protein ligase E3 component n-recognin 4
 8060
 0.2
chr6_159462884_159463035 0.24 TAGAP
 T-cell activation RhoGTPase activating protein
 3091
 0.25
chr1_36172716_36172867 0.24 ENSG00000239859
 .
 916
 0.53
chrX_120693101_120693333 0.24 ENSG00000265456
 .
 188391
 0.03
chr16_27244955_27245106 0.24 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 631
 0.7
chr3_59430359_59430723 0.24 C3orf67
 chromosome 3 open reading frame 67
 394731
 0.01
chr12_9148612_9148857 0.24 RP11-259O18.4
428
 0.8
chr19_30166083_30166320 0.24 PLEKHF1
 pleckstrin homology domain containing, family F (with FYVE domain) member 1
 8420
 0.23
chr3_28294093_28294244 0.24 CMC1
 C-x(9)-C motif containing 1
 1051
 0.66
chr15_34841604_34841755 0.24 GOLGA8B
 golgin A8 family, member B
 13468
 0.17
chr9_96357787_96357938 0.24 PHF2
 PHD finger protein 2
 18953
 0.19
chr13_99214255_99214406 0.24 STK24
 serine/threonine kinase 24
 14787
 0.2
chr8_11309548_11309973 0.24 FAM167A
 family with sequence similarity 167, member A
 6882
 0.16
chr15_81299308_81299459 0.24 C15orf26
 chromosome 15 open reading frame 26
 9
 0.97
chr8_61694776_61694927 0.24 RP11-33I11.2
27314
 0.22
chr12_53593792_53594465 0.23 ITGB7
 integrin, beta 7
 99
 0.94
chr3_71187126_71187427 0.23 FOXP1
 forkhead box P1
 7288
 0.32

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE40

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.3 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.2 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132) metaphase(GO:0051323)
0.1 0.3 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.1 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.2 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0070100 regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.0 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.4 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0052255 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0044266 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.2 GO:0003407 neural retina development(GO:0003407)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.0 GO:2000318 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:0048536 spleen development(GO:0048536)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.0 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.4 GO:0019079 viral genome replication(GO:0019079)
0.0 0.1 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.3 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0032222 regulation of synaptic transmission, cholinergic(GO:0032222)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.0 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0051806 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.2 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:1903319 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0071600 otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0 0.0 GO:0072124 cellular response to heparin(GO:0071504) glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124) metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239) regulation of glomerulus development(GO:0090192)
0.0 0.0 GO:0046636 negative regulation of alpha-beta T cell activation(GO:0046636)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.0 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0032142 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.5 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.4 REACTOME CELL CYCLE CHECKPOINTS Genes involved in Cell Cycle Checkpoints
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins