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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for BHLHE40

Z-value: 1.28

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Transcription factors associated with BHLHE40

Gene Symbol	Gene ID	Gene Info
BHLHE40 Ensembl NCBI GeneCards UniProt	ENSG00000134107.4	BHLHE40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
BHLHE40	chr3_4991634_4991797	29086	0.162405	-0.53	1.4e-01	Click!
BHLHE40	chr3_5020639_5020790	87	0.941773	0.51	1.6e-01	Click!
BHLHE40	chr3_4994783_4994934	25943	0.169522	-0.49	1.8e-01	Click!
BHLHE40	chr3_5019096_5019422	1542	0.374689	0.41	2.7e-01	Click!
BHLHE40	chr3_5018310_5018816	2238	0.297469	0.37	3.3e-01	Click!

Activity of the BHLHE40 motif across conditions

Conditions sorted by the z-value of the BHLHE40 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_157548637_157548975	2.10	ARID1B	AT rich interactive domain 1B (SWI1-like)	78761	0.11
chr6_157548368_157548619	1.30	ARID1B	AT rich interactive domain 1B (SWI1-like)	78448	0.11
chr6_150401228_150401379	0.68	ULBP3	UL16 binding protein 3	11072	0.18
chr11_95393873_95394024	0.49	FAM76B	family with sequence similarity 76, member B	126021	0.05
chr4_40303302_40303674	0.45	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	33858	0.17
chr1_209944656_209944807	0.44	TRAF3IP3	TRAF3 interacting protein 3	2771	0.19
chr7_2070925_2071076	0.44	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	48648	0.17
chr9_92138368_92138605	0.42	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	25441	0.19
chr11_118178245_118178503	0.42	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	2760	0.18
chr2_106604937_106605088	0.42	C2orf40	chromosome 2 open reading frame 40	74738	0.11
chr15_93579130_93579323	0.42	CHD2	chromodomain helicase DNA binding protein 2	27130	0.2
chr20_57973693_57973970	0.42	ENSG00000263903	.	52296	0.16
chr1_42271419_42271644	0.41	ENSG00000264896	.	46719	0.18
chr2_149284716_149284924	0.40	MBD5	methyl-CpG binding domain protein 5	58526	0.15
chr1_2950991_2951142	0.40	ACTRT2	actin-related protein T2	13020	0.19
chr9_92105986_92106169	0.40	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	6270	0.24
chr3_46416627_46416863	0.40	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	2584	0.23
chr6_71360263_71360634	0.39	SMAP1	small ArfGAP 1	17031	0.26
chr3_128032806_128032957	0.39	ENSG00000221067	.	48127	0.15
chr7_150639030_150639181	0.38	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	13889	0.15
chr2_169290603_169290754	0.38	ENSG00000239230	.	7037	0.21
chr12_58153080_58153231	0.38	MARCH9	membrane-associated ring finger (C3HC4) 9	1885	0.12
chr12_25432795_25432959	0.38	KRAS	Kirsten rat sarcoma viral oncogene homolog	29007	0.18
chr20_50720819_50720982	0.37	ZFP64	ZFP64 zinc finger protein	489	0.89
chr1_241839762_241839978	0.37	WDR64	WD repeat domain 64	7012	0.22
chr1_235377409_235377560	0.37	ARID4B	AT rich interactive domain 4B (RBP1-like)	253	0.92
chr7_1085411_1085702	0.37	GPR146	G protein-coupled receptor 146	1344	0.26
chr14_100540531_100540793	0.36	CTD-2376I20.1		553	0.71
chr7_139924008_139924237	0.36	ENSG00000199971	.	14651	0.16
chr11_748009_748200	0.35	TALDO1	transaldolase 1	676	0.44
chr15_44958521_44958824	0.35	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	2011	0.24
chr13_43563311_43563462	0.35	EPSTI1	epithelial stromal interaction 1 (breast)	1981	0.43
chr2_113943965_113944116	0.35	PSD4	pleckstrin and Sec7 domain containing 4	9817	0.14
chr9_123641457_123641690	0.35	PHF19	PHD finger protein 19	1967	0.31
chr16_89850957_89851182	0.34	FANCA	Fanconi anemia, complementation group A	31974	0.1
chr3_18416180_18416331	0.34	RP11-158G18.1		34872	0.19
chr10_63810330_63810481	0.34	ARID5B	AT rich interactive domain 5B (MRF1-like)	1435	0.54
chr15_65075233_65075384	0.34	RBPMS2	RNA binding protein with multiple splicing 2	7522	0.14
chr15_32635679_32635830	0.34	ENSG00000221444	.	49919	0.09
chr1_101742974_101743225	0.34	RP4-575N6.5		34385	0.14
chr19_16486076_16486459	0.34	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	13503	0.14
chr7_50426987_50427896	0.33	IKZF1	IKAROS family zinc finger 1 (Ikaros)	60196	0.13
chr5_131347971_131348122	0.33	ACSL6	acyl-CoA synthetase long-chain family member 6	176	0.88
chr6_36487605_36487756	0.33	ENSG00000239964	.	2288	0.23
chr1_194025907_194026313	0.33	ENSG00000252241	.	325036	0.01
chrX_128889315_128889636	0.33	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	16477	0.19
chr9_4605304_4605466	0.33	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	33050	0.16
chr16_57041025_57041193	0.33	NLRC5	NLR family, CARD domain containing 5	2711	0.2
chr1_209944824_209944985	0.33	TRAF3IP3	TRAF3 interacting protein 3	2944	0.19
chr17_38076794_38077078	0.32	GSDMB	gasdermin B	2033	0.21
chr12_2799901_2800122	0.32	CACNA1C-AS1	CACNA1C antisense RNA 1	273	0.91
chr3_33101505_33101658	0.32	GLB1	galactosidase, beta 1	36703	0.13
chr12_92726454_92726695	0.32	RP11-693J15.4		88733	0.08
chr1_12149159_12149332	0.32	ENSG00000201135	.	11204	0.15
chr17_2699183_2699336	0.32	RAP1GAP2	RAP1 GTPase activating protein 2	473	0.8
chr14_25162667_25162947	0.32	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	59334	0.11
chr17_18858474_18858633	0.32	AC090286.4		1091	0.36
chr16_57634856_57635007	0.31	GPR56	G protein-coupled receptor 56	9633	0.15
chr22_50754075_50754226	0.31	XX-C283C717.1		1090	0.31
chr5_157940155_157940453	0.31	CTD-2363C16.1		469710	0.01
chr9_135382524_135382903	0.31	BARHL1	BarH-like homeobox 1	74859	0.09
chr11_64821935_64822086	0.31	NAALADL1	N-acetylated alpha-linked acidic dipeptidase-like 1	3983	0.08
chr5_171543346_171543497	0.31	ENSG00000266671	.	35441	0.16
chr1_112045793_112046152	0.31	ADORA3	adenosine A3 receptor	138	0.93
chr7_132121999_132122205	0.31	AC011625.1		85009	0.1
chr2_10815541_10815692	0.31	NOL10	nucleolar protein 10	3800	0.22
chr7_158991213_158991434	0.31	VIPR2	vasoactive intestinal peptide receptor 2	53674	0.18
chr12_131796444_131796595	0.31	ENSG00000212251	.	12223	0.23
chr3_187692256_187692598	0.31	LPP	LIM domain containing preferred translocation partner in lipoma	178645	0.03
chr10_11309961_11310112	0.30	CELF2-AS1	CELF2 antisense RNA 1	51811	0.15
chr5_98267544_98267695	0.30	ENSG00000200351	.	4832	0.23
chr3_45906834_45907101	0.30	CCR9	chemokine (C-C motif) receptor 9	21029	0.15
chr2_198143456_198143859	0.30	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	23586	0.16
chr20_62859464_62859615	0.30	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	27555	0.17
chr5_1313612_1313923	0.30	ENSG00000263670	.	4275	0.2
chr1_20013079_20013230	0.30	HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	21374	0.16
chr11_114053249_114053976	0.30	NNMT	nicotinamide N-methyltransferase	74941	0.09
chr11_96024786_96024937	0.30	ENSG00000266192	.	49741	0.14
chr17_73239171_73239322	0.30	GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	4084	0.11
chr11_113955241_113955493	0.30	ENSG00000221112	.	2284	0.34
chr18_21509698_21509962	0.30	LAMA3	laminin, alpha 3	1627	0.41
chr14_98899836_98899987	0.30	ENSG00000241757	.	81910	0.11
chr2_128399438_128399670	0.30	LIMS2	LIM and senescent cell antigen-like domains 2	152	0.94
chr15_61135667_61135839	0.29	RP11-554D20.1		78814	0.11
chr17_76745970_76746190	0.29	CYTH1	cytohesin 1	13108	0.19
chr6_137710654_137710959	0.29	OLIG3	oligodendrocyte transcription factor 3	104725	0.07
chr1_227949174_227949396	0.29	SNAP47	synaptosomal-associated protein, 47kDa	13521	0.16
chr8_100024823_100024974	0.29	VPS13B	vacuolar protein sorting 13 homolog B (yeast)	596	0.74
chr1_160645057_160645403	0.29	RP11-404F10.2		1918	0.29
chr21_44252788_44252947	0.29	WDR4	WD repeat domain 4	46774	0.13
chr5_133376557_133376708	0.29	VDAC1	voltage-dependent anion channel 1	35808	0.17
chr19_42027703_42027944	0.29	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	28063	0.13
chr2_106404052_106404457	0.29	NCK2	NCK adaptor protein 2	28761	0.23
chr14_100537205_100537447	0.28	CTD-2376I20.1		3889	0.18
chr12_133349779_133349930	0.28	ANKLE2	ankyrin repeat and LEM domain containing 2	11380	0.15
chr2_662119_662318	0.28	TMEM18	transmembrane protein 18	13557	0.2
chr8_27226083_27226368	0.28	PTK2B	protein tyrosine kinase 2 beta	11943	0.22
chr1_229228666_229228817	0.28	RP5-1061H20.5		134568	0.04
chr9_140165488_140165705	0.28	TOR4A	torsin family 4, member A	6605	0.07
chr10_126849895_126850046	0.28	CTBP2	C-terminal binding protein 2	340	0.93
chrX_46471596_46471846	0.28	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	38502	0.17
chr1_54815665_54815816	0.28	SSBP3	single stranded DNA binding protein 3	55437	0.11
chr13_114906998_114907153	0.28	RASA3	RAS p21 protein activator 3	8989	0.22
chr8_66854346_66854497	0.27	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	79374	0.1
chr17_78637163_78637475	0.27	RPTOR	regulatory associated protein of MTOR, complex 1	118051	0.05
chr1_1107776_1107927	0.27	TTLL10	tubulin tyrosine ligase-like family, member 10	1432	0.2
chr17_71826931_71827082	0.27	SDK2	sidekick cell adhesion molecule 2	186778	0.03
chr14_22409773_22409924	0.27	ENSG00000222776	.	161063	0.03
chr15_64151124_64151275	0.27	ENSG00000199156	.	12019	0.21
chr16_27206515_27206666	0.27	KDM8	lysine (K)-specific demethylase 8	8217	0.19
chr4_89202595_89202746	0.27	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent, 1K	2372	0.23
chr21_46496959_46497110	0.27	ADARB1	adenosine deaminase, RNA-specific, B1	2519	0.22
chr20_47430608_47430759	0.27	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	13737	0.26
chr14_61827530_61827767	0.27	PRKCH	protein kinase C, eta	144	0.97
chr6_167524624_167524999	0.27	CCR6	chemokine (C-C motif) receptor 6	484	0.81
chr13_99849164_99849315	0.27	UBAC2	UBA domain containing 2	3789	0.23
chr16_85933118_85933269	0.27	IRF8	interferon regulatory factor 8	424	0.87
chr14_105532821_105533069	0.27	GPR132	G protein-coupled receptor 132	1163	0.49
chr7_2750642_2751031	0.27	AMZ1	archaelysin family metallopeptidase 1	23000	0.18
chr2_3243298_3243449	0.27	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	61863	0.13
chr5_56122812_56123396	0.27	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	11703	0.17
chr9_92450655_92450815	0.27	GADD45G	growth arrest and DNA-damage-inducible, gamma	230782	0.02
chr10_22969605_22969760	0.27	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	33355	0.22
chr8_125685655_125685918	0.27	MTSS1	metastasis suppressor 1	54071	0.13
chr21_32929274_32929425	0.27	TIAM1	T-cell lymphoma invasion and metastasis 1	1941	0.32
chr10_8087441_8087780	0.27	GATA3	GATA binding protein 3	9046	0.32
chr12_112545861_112546012	0.26	NAA25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	611	0.66
chr1_182599288_182599608	0.26	RGS16	regulator of G-protein signaling 16	25905	0.17
chr6_157548074_157548363	0.26	ARID1B	AT rich interactive domain 1B (SWI1-like)	78173	0.11
chr19_15624982_15625133	0.26	CYP4F22	cytochrome P450, family 4, subfamily F, polypeptide 22	5753	0.16
chr17_43307469_43307750	0.26	CTD-2020K17.1		8020	0.1
chr3_128518442_128518718	0.26	RAB7A	RAB7A, member RAS oncogene family	4378	0.21
chr2_106371801_106372035	0.26	NCK2	NCK adaptor protein 2	9730	0.3
chr1_157693341_157693492	0.26	FCRL3	Fc receptor-like 3	22769	0.17
chr3_171826118_171826452	0.26	FNDC3B	fibronectin type III domain containing 3B	18479	0.26
chr20_62362374_62362787	0.26	LIME1	Lck interacting transmembrane adaptor 1	5055	0.09
chr21_45502719_45503242	0.26	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	24191	0.15
chr16_68389761_68390217	0.26	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	14919	0.11
chr4_2816087_2816379	0.26	SH3BP2	SH3-domain binding protein 2	2202	0.32
chr3_186760165_186760316	0.26	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	1291	0.54
chr1_226039631_226039809	0.26	RP11-285F7.2		5497	0.14
chr12_133014236_133014611	0.26	MUC8	mucin 8	36303	0.16
chr20_57735532_57735874	0.26	ZNF831	zinc finger protein 831	30372	0.2
chr1_42269178_42269372	0.26	ENSG00000264896	.	44463	0.19
chr6_167460456_167460849	0.26	FGFR1OP	FGFR1 oncogene partner	47756	0.1
chr8_144910846_144910997	0.26	PUF60	poly-U binding splicing factor 60KDa	275	0.81
chr7_152039023_152039174	0.26	ENSG00000253088	.	60767	0.12
chr16_17440476_17440787	0.26	XYLT1	xylosyltransferase I	124107	0.06
chr15_76574850_76575217	0.26	ETFA	electron-transfer-flavoprotein, alpha polypeptide	9799	0.23
chr20_60867419_60867570	0.25	ADRM1	adhesion regulating molecule 1	10567	0.12
chr18_21551706_21552127	0.25	TTC39C	tetratricopeptide repeat domain 39C	20821	0.16
chr10_126414122_126414344	0.25	FAM53B	family with sequence similarity 53, member B	17306	0.16
chr21_43834242_43834420	0.25	ENSG00000252619	.	3371	0.17
chr22_37641156_37641409	0.25	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	794	0.57
chr13_100039907_100040178	0.25	ENSG00000207719	.	31657	0.16
chr1_78354309_78354460	0.25	NEXN	nexilin (F actin binding protein)	37	0.95
chr3_187719085_187719236	0.25	LPP	LIM domain containing preferred translocation partner in lipoma	151912	0.04
chr11_76376085_76376254	0.25	LRRC32	leucine rich repeat containing 32	4875	0.2
chr1_101711671_101711822	0.25	RP4-575N6.5		3032	0.21
chr1_77884409_77884560	0.25	ENSG00000251767	.	1526	0.44
chr13_110222272_110222771	0.25	LINC00676	long intergenic non-protein coding RNA 676	158108	0.04
chr7_31064429_31064580	0.25	ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	27572	0.21
chr2_64553101_64553267	0.25	ENSG00000264297	.	14709	0.25
chr13_114909698_114910252	0.25	RASA3	RAS p21 protein activator 3	11889	0.21
chr1_200980853_200981004	0.25	KIF21B	kinesin family member 21B	11608	0.18
chr3_38036912_38037201	0.25	VILL	villin-like	1412	0.32
chr6_20206050_20206262	0.25	RP11-239H6.2		6162	0.24
chr11_2489014_2489234	0.25	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	6007	0.18
chr10_13932808_13933126	0.25	FRMD4A	FERM domain containing 4A	32055	0.2
chr14_100610702_100610964	0.25	DEGS2	delta(4)-desaturase, sphingolipid 2	15099	0.12
chr22_26690400_26690699	0.25	SEZ6L	seizure related 6 homolog (mouse)-like	2332	0.34
chr7_92666364_92666515	0.25	ENSG00000266794	.	65826	0.11
chr3_9992673_9992875	0.25	PRRT3	proline-rich transmembrane protein 3	1300	0.22
chr15_34695379_34695530	0.25	GOLGA8A	golgin A8 family, member A	4434	0.16
chr11_14076377_14076528	0.25	ENSG00000212365	.	80080	0.11
chr4_100739674_100739989	0.25	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	1828	0.43
chr2_219233652_219233882	0.24	ENSG00000225062	.	1209	0.27
chr16_50318201_50318668	0.24	ADCY7	adenylate cyclase 7	3388	0.25
chr18_21547738_21547925	0.24	LAMA3	laminin, alpha 3	17974	0.17
chr7_2138652_2138817	0.24	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	8609	0.28
chr10_102107561_102107838	0.24	SCD	stearoyl-CoA desaturase (delta-9-desaturase)	818	0.47
chr15_53075384_53075631	0.24	ONECUT1	one cut homeobox 1	2127	0.43
chr1_167618740_167619238	0.24	RP3-455J7.4		19078	0.18
chr1_19400551_19400797	0.24	UBR4	ubiquitin protein ligase E3 component n-recognin 4	8060	0.2
chr6_159462884_159463035	0.24	TAGAP	T-cell activation RhoGTPase activating protein	3091	0.25
chr1_36172716_36172867	0.24	ENSG00000239859	.	916	0.53
chrX_120693101_120693333	0.24	ENSG00000265456	.	188391	0.03
chr16_27244955_27245106	0.24	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	631	0.7
chr3_59430359_59430723	0.24	C3orf67	chromosome 3 open reading frame 67	394731	0.01
chr12_9148612_9148857	0.24	RP11-259O18.4		428	0.8
chr19_30166083_30166320	0.24	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	8420	0.23
chr3_28294093_28294244	0.24	CMC1	C-x(9)-C motif containing 1	1051	0.66
chr15_34841604_34841755	0.24	GOLGA8B	golgin A8 family, member B	13468	0.17
chr9_96357787_96357938	0.24	PHF2	PHD finger protein 2	18953	0.19
chr13_99214255_99214406	0.24	STK24	serine/threonine kinase 24	14787	0.2
chr8_11309548_11309973	0.24	FAM167A	family with sequence similarity 167, member A	6882	0.16
chr15_81299308_81299459	0.24	C15orf26	chromosome 15 open reading frame 26	9	0.97
chr8_61694776_61694927	0.24	RP11-33I11.2		27314	0.22
chr12_53593792_53594465	0.23	ITGB7	integrin, beta 7	99	0.94
chr3_71187126_71187427	0.23	FOXP1	forkhead box P1	7288	0.32

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.5	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.4	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.3	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.2	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0007132	meiotic metaphase I(GO:0007132) metaphase(GO:0051323)
0.1	0.3	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.6	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.3	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.2	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0070100	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.0	GO:0001562	response to protozoan(GO:0001562)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.0	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.5	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.4	GO:0031670	cellular response to nutrient(GO:0031670)
0.0	0.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0052255	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.4	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.0	GO:0044266	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.0	GO:0051580	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.1	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.5	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.2	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.2	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.2	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.0	GO:2000318	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0048536	spleen development(GO:0048536)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.0	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.3	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.4	GO:0019079	viral genome replication(GO:0019079)
0.0	0.1	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.1	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.3	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.0	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.2	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.0	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.0	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.0	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0071600	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0	0.0	GO:0072124	cellular response to heparin(GO:0071504) glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124) metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239) regulation of glomerulus development(GO:0090192)
0.0	0.0	GO:0046636	negative regulation of alpha-beta T cell activation(GO:0046636)
0.0	0.0	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.7	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.2	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.3	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0032142	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.2	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.5	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
1.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	1.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.4	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins