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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for BRCA1

Z-value: 1.85

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Transcription factors associated with BRCA1

Gene Symbol	Gene ID	Gene Info
BRCA1 Ensembl NCBI GeneCards UniProt	ENSG00000012048.15	BRCA1 DNA repair associated

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_41236556_41236707	BRCA1	7210	0.132889	-0.54	1.4e-01	Click!
chr17_41277762_41278065	BRCA1	413	0.781317	0.46	2.1e-01	Click!
chr17_41275995_41276146	BRCA1	62	0.962344	-0.38	3.1e-01	Click!
chr17_41276282_41276723	BRCA1	370	0.812669	-0.31	4.1e-01	Click!
chr17_41246246_41246397	BRCA1	1562	0.295366	-0.26	4.9e-01	Click!

Activity of the BRCA1 motif across conditions

Conditions sorted by the z-value of the BRCA1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_48031354_48031544	0.73	AC103828.1		5958	0.23
chr2_136813885_136814194	0.61	AC093391.2		44004	0.15
chr10_26769081_26769327	0.60	ENSG00000199733	.	29314	0.21
chr3_71434119_71434715	0.59	FOXP1	forkhead box P1	80506	0.1
chr17_76753532_76753758	0.59	CYTH1	cytohesin 1	20673	0.17
chr16_89831627_89831849	0.56	FANCA	Fanconi anemia, complementation group A	20268	0.11
chr11_117821389_117821783	0.54	TMPRSS13	transmembrane protease, serine 13	21412	0.15
chr1_120436878_120437115	0.53	ADAM30	ADAM metallopeptidase domain 30	2122	0.34
chr2_232410956_232411379	0.53	NMUR1	neuromedin U receptor 1	15961	0.14
chr16_27458426_27458577	0.51	IL21R-AS1	IL21R antisense RNA 1	6213	0.2
chr4_153143340_153143491	0.47	ENSG00000266244	.	6205	0.26
chr9_92151633_92152777	0.46	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	39160	0.16
chr7_139312464_139312655	0.46	CLEC2L	C-type lectin domain family 2, member L	103731	0.06
chr2_42342113_42342387	0.46	EML4	echinoderm microtubule associated protein like 4	54240	0.12
chr17_76117719_76118274	0.45	TMC6	transmembrane channel-like 6	833	0.48
chr19_54374478_54374854	0.45	MYADM	myeloid-associated differentiation marker	1647	0.15
chr10_126374521_126374754	0.44	FAM53B-AS1	FAM53B antisense RNA 1	17557	0.2
chr1_154438581_154439022	0.44	RP11-350G8.9		13687	0.12
chr13_46747571_46748374	0.44	ENSG00000240767	.	4089	0.19
chr1_25323926_25324151	0.43	ENSG00000264371	.	25956	0.17
chr4_81064367_81064674	0.43	PRDM8	PR domain containing 8	40919	0.16
chr22_40798855_40799170	0.43	SGSM3	small G protein signaling modulator 3	5305	0.17
chr2_242804112_242804263	0.42	PDCD1	programmed cell death 1	3127	0.15
chr17_47825562_47826034	0.42	FAM117A	family with sequence similarity 117, member A	15695	0.14
chr15_78336776_78336956	0.42	ENSG00000221476	.	5993	0.15
chr16_50726638_50726789	0.42	NOD2	nucleotide-binding oligomerization domain containing 2	824	0.49
chr10_44475712_44476330	0.42	ENSG00000238957	.	53967	0.17
chr6_149449848_149450071	0.40	ENSG00000263481	.	47971	0.15
chrX_135851684_135852073	0.40	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1092	0.49
chr6_138249911_138250062	0.40	RP11-356I2.4		60616	0.13
chr21_15899707_15900071	0.40	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	18773	0.23
chr17_14103084_14103297	0.39	AC005224.2		10615	0.2
chr8_82053234_82053464	0.39	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	29046	0.23
chr3_195277399_195277835	0.38	AC091633.3		4198	0.18
chr10_112618995_112619585	0.38	PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	12275	0.14
chr9_129232305_129232865	0.38	ENSG00000252985	.	43413	0.14
chr1_8488032_8488525	0.38	RP5-1115A15.1		2580	0.27
chr19_41332938_41333153	0.38	EGLN2	egl-9 family hypoxia-inducible factor 2	19897	0.11
chr7_105896584_105896735	0.38	NAMPT	nicotinamide phosphoribosyltransferase	28708	0.18
chr9_130624750_130625121	0.38	ENSG00000263979	.	6839	0.08
chr18_43268528_43268819	0.38	SLC14A2	solute carrier family 14 (urea transporter), member 2	22566	0.17
chr4_89875013_89875192	0.37	FAM13A	family with sequence similarity 13, member A	75949	0.11
chr1_9716017_9716306	0.37	C1orf200	chromosome 1 open reading frame 200	1517	0.35
chr17_14104233_14104499	0.37	AC005224.2		9439	0.2
chrX_147391899_147392419	0.37	AC002368.4		189976	0.03
chr1_92195446_92195656	0.36	ENSG00000239794	.	100080	0.08
chr11_35067072_35067223	0.36	PDHX	pyruvate dehydrogenase complex, component X	67816	0.09
chr22_40731956_40732213	0.36	ADSL	adenylosuccinate lyase	10423	0.19
chr8_37731564_37731977	0.36	RAB11FIP1	RAB11 family interacting protein 1 (class I)	3865	0.18
chrX_101185777_101185963	0.35	ZMAT1	zinc finger, matrin-type 1	867	0.63
chr14_38551462_38551750	0.35	CTD-2058B24.2		8757	0.27
chr17_72740189_72740398	0.35	ENSG00000264624	.	4459	0.11
chr9_77771490_77771711	0.35	ENSG00000200041	.	24937	0.18
chr1_203673251_203673440	0.35	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	19680	0.17
chrX_13099709_13099860	0.34	FAM9C	family with sequence similarity 9, member C	36983	0.2
chr11_64539683_64539961	0.34	SF1	splicing factor 1	3279	0.15
chr20_25022537_25022783	0.34	ACSS1	acyl-CoA synthetase short-chain family member 1	9321	0.2
chr16_89850957_89851182	0.34	FANCA	Fanconi anemia, complementation group A	31974	0.1
chr7_98979536_98979688	0.34	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	7259	0.12
chr1_26634086_26634237	0.34	UBXN11	UBX domain protein 11	681	0.56
chr2_68978274_68978498	0.34	ARHGAP25	Rho GTPase activating protein 25	16372	0.23
chr1_26529372_26529523	0.34	RP11-231P20.2		6785	0.11
chr5_156675901_156676151	0.34	ENSG00000222086	.	13717	0.13
chr2_137079682_137079833	0.34	ENSG00000251976	.	68145	0.13
chr17_63022313_63022486	0.34	RP11-583F2.5		25628	0.14
chr14_93036433_93036584	0.34	RIN3	Ras and Rab interactor 3	56360	0.15
chr1_100857149_100857300	0.34	ENSG00000216067	.	12893	0.2
chr8_22407957_22408202	0.34	SORBS3	sorbin and SH3 domain containing 3	1129	0.34
chr1_32723117_32723278	0.33	LCK	lymphocyte-specific protein tyrosine kinase	6322	0.09
chr22_48486520_48486723	0.33	ENSG00000266508	.	183555	0.03
chr4_129783038_129783517	0.33	JADE1	jade family PHD finger 1	30689	0.24
chr5_49712966_49713136	0.33	EMB	embigin	11510	0.32
chr8_27228698_27228876	0.33	PTK2B	protein tyrosine kinase 2 beta	9381	0.23
chr13_32616590_32616779	0.33	FRY-AS1	FRY antisense RNA 1	10908	0.22
chr1_66810588_66810754	0.33	PDE4B	phosphodiesterase 4B, cAMP-specific	9394	0.31
chr9_132656652_132657013	0.33	FNBP1	formin binding protein 1	24757	0.14
chr21_32553088_32553598	0.33	TIAM1	T-cell lymphoma invasion and metastasis 1	50804	0.17
chr19_13993263_13993689	0.33	NANOS3	nanos homolog 3 (Drosophila)	5413	0.09
chr5_158631981_158632133	0.33	RNF145	ring finger protein 145	2585	0.25
chr16_89826511_89826662	0.33	FANCA	Fanconi anemia, complementation group A	15116	0.12
chr1_160592657_160592947	0.33	SLAMF1	signaling lymphocytic activation molecule family member 1	24009	0.13
chr19_40467088_40467239	0.33	PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	9749	0.15
chr4_122059678_122059966	0.33	TNIP3	TNFAIP3 interacting protein 3	3232	0.3
chr3_13456823_13457198	0.33	NUP210	nucleoporin 210kDa	4799	0.27
chr16_85970246_85970549	0.33	IRF8	interferon regulatory factor 8	22478	0.22
chr19_33651116_33651486	0.33	ENSG00000264355	.	16677	0.12
chr17_8801323_8801785	0.33	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	13270	0.21
chr4_20701189_20701398	0.33	PACRGL	PARK2 co-regulated-like	743	0.77
chr3_50312095_50312246	0.33	LSMEM2	leucine-rich single-pass membrane protein 2	4288	0.09
chr17_78755506_78755665	0.33	RP11-28G8.1		23847	0.21
chr1_2078854_2079005	0.32	RP5-892K4.1		2211	0.21
chr11_48064508_48064761	0.32	AC103828.1		27227	0.18
chr1_66811583_66811734	0.32	PDE4B	phosphodiesterase 4B, cAMP-specific	8407	0.31
chr16_89505998_89506258	0.32	ENSG00000252887	.	3598	0.16
chr14_51253681_51254112	0.32	NIN	ninein (GSK3B interacting protein)	20383	0.15
chr18_811408_811581	0.32	YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	745	0.61
chr1_112176333_112176744	0.32	RAP1A	RAP1A, member of RAS oncogene family	13769	0.17
chr2_145339342_145339694	0.32	ZEB2	zinc finger E-box binding homeobox 2	60897	0.14
chr11_48041048_48041486	0.32	AC103828.1		3860	0.26
chr10_31040172_31040377	0.32	SVILP1	supervillin pseudogene 1	55424	0.14
chr7_77351466_77351617	0.32	RSBN1L	round spermatid basic protein 1-like	25073	0.21
chr8_128189680_128189831	0.32	POU5F1B	POU class 5 homeobox 1B	236780	0.02
chr12_1777807_1778135	0.32	ENSG00000266043	.	8425	0.19
chr17_47816177_47816540	0.32	FAM117A	family with sequence similarity 117, member A	14469	0.14
chr13_41145097_41145267	0.31	AL133318.1	Uncharacterized protein	33859	0.2
chr7_37024417_37024850	0.31	ELMO1	engulfment and cell motility 1	32	0.98
chrX_131347819_131347970	0.31	RAP2C-AS1	RAP2C antisense RNA 1	3281	0.27
chr18_74808853_74809004	0.31	MBP	myelin basic protein	8289	0.3
chr4_1211290_1211520	0.31	CTBP1	C-terminal binding protein 1	3155	0.18
chr12_3838064_3838293	0.31	ENSG00000222338	.	2685	0.33
chr1_108439584_108439849	0.31	VAV3-AS1	VAV3 antisense RNA 1	67349	0.11
chr8_126948244_126948556	0.31	ENSG00000206695	.	35205	0.24
chr2_235397973_235398130	0.31	ARL4C	ADP-ribosylation factor-like 4C	7193	0.34
chr7_37483297_37483448	0.31	ELMO1	engulfment and cell motility 1	5181	0.21
chr22_38438083_38438604	0.31	RP5-1039K5.16		8108	0.11
chr1_12404837_12405275	0.31	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	64868	0.11
chr12_32121700_32121855	0.31	KIAA1551	KIAA1551	6354	0.25
chrX_77038763_77038914	0.31	ATRX	alpha thalassemia/mental retardation syndrome X-linked	2864	0.32
chr3_53069303_53069506	0.31	SFMBT1	Scm-like with four mbt domains 1	9877	0.18
chr13_112041909_112042060	0.31	TEX29	testis expressed 29	68969	0.13
chr8_103117650_103117985	0.31	NCALD	neurocalcin delta	18361	0.2
chr11_78646556_78646707	0.31	TENM4	teneurin transmembrane protein 4	31700	0.2
chr1_209924360_209924511	0.30	TRAF3IP3	TRAF3 interacting protein 3	4942	0.16
chr17_37968472_37968629	0.30	IKZF3	IKAROS family zinc finger 3 (Aiolos)	34072	0.11
chr11_102319067_102319257	0.30	TMEM123	transmembrane protein 123	1021	0.49
chr11_34107866_34108017	0.30	NAT10	N-acetyltransferase 10 (GCN5-related)	19208	0.21
chr6_35016042_35016193	0.30	TCP11	t-complex 11, testis-specific	72705	0.1
chr3_32500825_32501088	0.30	CMTM6	CKLF-like MARVEL transmembrane domain containing 6	43944	0.14
chr2_3245519_3245788	0.30	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	59583	0.14
chr3_15319690_15320104	0.30	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	2345	0.23
chr10_115856335_115856784	0.30	ENSG00000253066	.	14614	0.19
chr20_57733456_57733718	0.30	ZNF831	zinc finger protein 831	32488	0.19
chr17_37252182_37252943	0.30	PLXDC1	plexin domain containing 1	11178	0.15
chr20_35258679_35258929	0.30	SLA2	Src-like-adaptor 2	15480	0.12
chr14_23030448_23030634	0.30	AE000662.93		4585	0.12
chr18_2969219_2969604	0.30	RP11-737O24.1		2395	0.24
chr7_50424313_50424464	0.30	IKZF1	IKAROS family zinc finger 1 (Ikaros)	57143	0.13
chr4_89881833_89881984	0.30	FAM13A	family with sequence similarity 13, member A	69143	0.12
chr6_5439844_5440017	0.30	RP1-232P20.1		18336	0.23
chr3_196370193_196370344	0.30	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	3622	0.16
chr1_92929305_92929569	0.30	GFI1	growth factor independent 1 transcription repressor	20074	0.23
chr16_78694346_78694497	0.30	RP11-264L1.3		126150	0.06
chr7_50353474_50353683	0.29	IKZF1	IKAROS family zinc finger 1 (Ikaros)	5260	0.32
chr17_42634506_42634717	0.29	FZD2	frizzled family receptor 2	314	0.89
chr5_75696951_75697217	0.29	IQGAP2	IQ motif containing GTPase activating protein 2	1990	0.45
chr16_68504541_68504803	0.29	ENSG00000199263	.	3895	0.19
chr14_90079697_90079956	0.29	FOXN3	forkhead box N3	5648	0.15
chr5_58448519_58448803	0.29	RP11-266N13.2		113073	0.07
chr5_175299080_175299718	0.29	CPLX2	complexin 2	414	0.87
chr1_110091795_110092043	0.29	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	686	0.5
chr7_76982518_76982669	0.29	GSAP	gamma-secretase activating protein	22909	0.22
chr11_36439029_36439247	0.29	RP11-219O3.2		8534	0.19
chr13_114833656_114834155	0.29	RASA3	RAS p21 protein activator 3	9533	0.25
chr5_53966243_53966648	0.29	SNX18	sorting nexin 18	152852	0.04
chr11_48057502_48058059	0.29	AC103828.1		20373	0.19
chr16_17087285_17087647	0.29	CTD-2576D5.4		140895	0.05
chr9_140622682_140622833	0.29	EHMT1	euchromatic histone-lysine N-methyltransferase 1	109303	0.05
chr17_56059241_56059441	0.29	VEZF1	vascular endothelial zinc finger 1	884	0.53
chr10_11223388_11223701	0.29	RP3-323N1.2		10205	0.22
chr18_11577383_11577660	0.29	NPIPB1P	nuclear pore complex interacting protein family, member B1, pseudogene	61939	0.14
chr5_176722952_176723252	0.29	RAB24	RAB24, member RAS oncogene family	7605	0.12
chr2_235392806_235393340	0.29	ARL4C	ADP-ribosylation factor-like 4C	12171	0.32
chr5_118608046_118608253	0.29	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	3700	0.23
chr2_12874585_12874736	0.29	ENSG00000264370	.	2833	0.34
chr1_160611400_160611728	0.29	SLAMF1	signaling lymphocytic activation molecule family member 1	5247	0.18
chr1_231747664_231747892	0.29	LINC00582	long intergenic non-protein coding RNA 582	58	0.98
chr19_3813652_3814105	0.29	MATK	megakaryocyte-associated tyrosine kinase	11751	0.11
chr14_105527301_105527518	0.29	GPR132	G protein-coupled receptor 132	3590	0.23
chr20_4793040_4793193	0.29	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	2653	0.29
chr11_95988623_95988872	0.29	ENSG00000266192	.	85855	0.09
chr16_85936515_85936777	0.29	IRF8	interferon regulatory factor 8	202	0.96
chr12_59707032_59707183	0.29	ENSG00000212599	.	55825	0.16
chr9_129234332_129234749	0.29	ENSG00000252985	.	45368	0.13
chr9_140534173_140534417	0.28	EHMT1	euchromatic histone-lysine N-methyltransferase 1	20841	0.12
chr1_207482314_207482508	0.28	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	12442	0.26
chr4_110612128_110612317	0.28	AC004067.5		938	0.57
chr5_55909103_55909387	0.28	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	7186	0.27
chr13_77622814_77623020	0.28	FBXL3	F-box and leucine-rich repeat protein 3	21587	0.15
chr13_114814477_114814986	0.28	RASA3	RAS p21 protein activator 3	28707	0.21
chr20_43997117_43997579	0.28	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)	5254	0.12
chr15_91967474_91967944	0.28	SV2B	synaptic vesicle glycoprotein 2B	198609	0.03
chr20_1657731_1657882	0.28	ENSG00000242348	.	10800	0.16
chr2_204586119_204586359	0.28	CD28	CD28 molecule	14823	0.22
chr2_235205909_235206126	0.28	ARL4C	ADP-ribosylation factor-like 4C	199227	0.03
chr3_69106261_69106412	0.28	TMF1	TATA element modulatory factor 1	4852	0.15
chr13_41063588_41063739	0.28	AL133318.1	Uncharacterized protein	47660	0.17
chr12_67678878_67679038	0.28	CAND1	cullin-associated and neddylation-dissociated 1	13794	0.32
chr2_84767316_84767481	0.28	DNAH6	dynein, axonemal, heavy chain 6	22455	0.25
chr9_123543481_123543767	0.28	FBXW2	F-box and WD repeat domain containing 2	12031	0.19
chr19_23455102_23455253	0.28	ZNF724P	zinc finger protein 724, pseudogene	21985	0.21
chr2_143910130_143910379	0.28	RP11-190J23.1		19487	0.22
chr9_93626852_93627053	0.28	SYK	spleen tyrosine kinase	37182	0.24
chr16_10959727_10960011	0.28	CIITA	class II, major histocompatibility complex, transactivator	11186	0.16
chr3_111031672_111031823	0.28	CD96	CD96 molecule	20181	0.27
chr3_141271384_141271598	0.28	RASA2-IT1	RASA2 intronic transcript 1 (non-protein coding)	27516	0.21
chr15_78395422_78395756	0.28	SH2D7	SH2 domain containing 7	10662	0.13
chr6_41150907_41151141	0.28	TREML2	triggering receptor expressed on myeloid cells-like 2	17908	0.11
chr11_118746463_118746614	0.28	CXCR5	chemokine (C-X-C motif) receptor 5	7937	0.1
chr14_89707669_89707837	0.28	FOXN3	forkhead box N3	60665	0.13
chr13_74453727_74453878	0.28	KLF12	Kruppel-like factor 12	115384	0.07

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BRCA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	GO:0002448	mast cell mediated immunity(GO:0002448)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.6	GO:0001820	serotonin secretion(GO:0001820)
0.1	0.3	GO:0060242	contact inhibition(GO:0060242)
0.1	0.8	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.3	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.3	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.2	GO:0048541	Peyer's patch development(GO:0048541)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.7	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.2	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.6	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.3	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.2	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.1	GO:0002886	regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.1	0.2	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.4	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1	0.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1	0.2	GO:0051665	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.7	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	0.3	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.2	GO:0007343	egg activation(GO:0007343)
0.1	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.2	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.2	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.9	GO:0045576	mast cell activation(GO:0045576)
0.1	0.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.4	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.3	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.5	GO:0044116	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.2	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.3	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.5	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.0	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.2	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.3	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	1.9	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.5	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.2	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.2	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.0	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0031060	regulation of histone methylation(GO:0031060)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.4	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.3	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.7	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.2	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0033700	phospholipid efflux(GO:0033700)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.3	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0032607	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0070293	renal absorption(GO:0070293)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.2	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.0	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.0	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.3	GO:0044036	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.0	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0060214	endocardium formation(GO:0060214)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:1903076	regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of plasma membrane organization(GO:1903729) regulation of protein localization to cell periphery(GO:1904375)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.3	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:1902743	regulation of lamellipodium organization(GO:1902743)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.0	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.1	GO:0060119	inner ear receptor cell development(GO:0060119)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0030147	obsolete natriuresis(GO:0030147)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.4	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:1902808	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0032239	regulation of nucleobase-containing compound transport(GO:0032239)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.0	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.0	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0019062	virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.0	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.0	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.0	GO:0000239	pachytene(GO:0000239)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0032418	lysosome localization(GO:0032418)
0.0	0.2	GO:0019400	alditol metabolic process(GO:0019400)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:1903427	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of reactive oxygen species biosynthetic process(GO:1903427) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0	0.0	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.3	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.0	0.1	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.0	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.1	GO:0030818	negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.0	GO:2001257	regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0	0.0	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.1	GO:0098534	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.0	GO:0051154	negative regulation of striated muscle cell differentiation(GO:0051154)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.9	GO:0001772	immunological synapse(GO:0001772)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.2	GO:0033011	perinuclear theca(GO:0033011)
0.1	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.5	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.8	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.8	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0031672	A band(GO:0031672)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0070938	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.3	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0060198	clathrin-sculpted vesicle(GO:0060198)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.9	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.3	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.7	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	1.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.3	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.5	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.9	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	1.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.3	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.4	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.4	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:0043141	5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.4	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	1.0	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.0	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0016160	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0035004	1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.7	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.2	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.2	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.2	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0051184	cofactor transporter activity(GO:0051184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	3.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.4	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.0	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.5	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	1.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.9	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)

Results for BRCA1

Z-value: 1.85

Motif logo

Transcription factors associated with BRCA1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the BRCA1 motif across conditions

Conditions sorted by the z-value of the BRCA1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of BRCA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: