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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CEBPB

Z-value: 4.25

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Transcription factors associated with CEBPB

Gene Symbol	Gene ID	Gene Info
CEBPB Ensembl NCBI GeneCards UniProt	ENSG00000172216.4	CEBPB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
CEBPB	chr20_48839570_48839721	32269	0.171967	0.84	5.0e-03	Click!
CEBPB	chr20_48836591_48836742	29290	0.177704	0.83	6.1e-03	Click!
CEBPB	chr20_48813539_48813690	6238	0.215810	0.81	7.9e-03	Click!
CEBPB	chr20_48890629_48890780	83328	0.081885	0.80	9.1e-03	Click!
CEBPB	chr20_48894188_48894339	86887	0.077614	0.79	1.1e-02	Click!

Activity of the CEBPB motif across conditions

Conditions sorted by the z-value of the CEBPB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_79005676_79005950	1.33	RP11-328K22.1		67886	0.12
chr1_92981375_92981732	1.31	GFI1	growth factor independent 1 transcription repressor	29120	0.22
chr3_137854767_137854935	1.26	A4GNT	alpha-1,4-N-acetylglucosaminyltransferase	3622	0.23
chrX_124430487_124430638	1.18	ENSG00000263886	.	8937	0.33
chr2_145138985_145139136	1.15	ZEB2	zinc finger E-box binding homeobox 2	48533	0.16
chr14_62086933_62087144	1.12	RP11-47I22.3	Uncharacterized protein	27100	0.2
chr2_75105185_75105336	1.04	HK2	hexokinase 2	42963	0.16
chr18_62086493_62086644	1.03	ENSG00000252818	.	130174	0.06
chr1_120929990_120930393	1.02	RP11-439A17.9		4557	0.18
chr12_66634245_66634457	0.99	ENSG00000266539	.	4949	0.18
chr9_125059861_125060215	0.98	ENSG00000264227	.	1604	0.3
chr6_6689312_6689469	0.95	LY86-AS1	LY86 antisense RNA 1	66386	0.13
chr1_10209396_10209547	0.95	ENSG00000201746	.	13855	0.17
chr1_53172748_53172915	0.95	ENSG00000239640	.	7240	0.15
chr12_29359171_29359322	0.93	FAR2	fatty acyl CoA reductase 2	17352	0.25
chr1_149759808_149759959	0.92	RP11-196G18.3		4693	0.09
chr2_228316015_228316264	0.91	ENSG00000266382	.	20709	0.18
chr2_208497932_208498495	0.91	METTL21A	methyltransferase like 21A	7562	0.19
chr1_158809280_158809431	0.91	MNDA	myeloid cell nuclear differentiation antigen	6336	0.21
chr19_43095842_43095993	0.90	CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	3165	0.26
chr2_43242041_43242192	0.90	ENSG00000207087	.	76516	0.11
chr4_38787451_38787728	0.90	TLR10	toll-like receptor 10	2979	0.22
chr17_72015639_72015790	0.88	RPL38	ribosomal protein L38	184007	0.03
chr2_57827769_57827920	0.88	ENSG00000212168	.	56174	0.18
chr3_31921623_31921774	0.87	OSBPL10	oxysterol binding protein-like 10	50101	0.16
chr2_7934741_7934909	0.87	ENSG00000221255	.	217853	0.02
chr10_81031239_81031413	0.87	ZMIZ1	zinc finger, MIZ-type containing 1	34649	0.19
chr9_88150913_88151201	0.87	AGTPBP1	ATP/GTP binding protein 1	145144	0.05
chr9_139806886_139807037	0.87	TRAF2	TNF receptor-associated factor 2	22974	0.06
chr19_823809_824065	0.86	LPPR3	hsa-mir-3187	1970	0.15
chr12_93515085_93515276	0.86	RP11-511B23.2		17687	0.2
chr4_15452943_15453218	0.86	CC2D2A	coiled-coil and C2 domain containing 2A	18409	0.16
chr20_23384481_23384632	0.86	NAPB	N-ethylmaleimide-sensitive factor attachment protein, beta	17542	0.1
chr14_75805696_75805973	0.85	FOS	FBJ murine osteosarcoma viral oncogene homolog	58938	0.09
chr20_20760824_20761172	0.84	ENSG00000264361	.	41624	0.19
chr8_28128426_28128577	0.84	PNOC	prepronociceptin	46002	0.13
chr20_44124475_44124626	0.83	RP3-461P17.9		8297	0.1
chr7_43498313_43498464	0.82	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	20864	0.22
chr2_120142991_120143276	0.82	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	17880	0.17
chr12_77142719_77142870	0.82	ZDHHC17	zinc finger, DHHC-type containing 17	14574	0.28
chr2_16812112_16812318	0.82	FAM49A	family with sequence similarity 49, member A	7871	0.32
chr2_192301147_192301752	0.81	MYO1B	myosin IB	25658	0.23
chr7_101498442_101498914	0.80	CTA-339C12.1		30669	0.18
chr9_97411720_97412079	0.80	FBP1	fructose-1,6-bisphosphatase 1	9368	0.23
chr21_15734345_15734716	0.80	HSPA13	heat shock protein 70kDa family, member 13	20928	0.24
chr1_197584008_197584159	0.80	DENND1B	DENN/MADD domain containing 1B	31733	0.21
chr1_153205323_153205520	0.80	PRR9	proline rich 9	15361	0.12
chr8_117457681_117457897	0.79	ENSG00000264815	.	158201	0.04
chr4_16533988_16534258	0.79	LDB2	LIM domain binding 2	63375	0.15
chr2_231323239_231323510	0.79	SP100	SP100 nuclear antigen	3776	0.28
chr1_211725187_211725382	0.79	SLC30A1	solute carrier family 30 (zinc transporter), member 1	26800	0.16
chr6_143645223_143645507	0.79	AL031320.1		114210	0.05
chr6_34240411_34240573	0.78	C6orf1	chromosome 6 open reading frame 1	23245	0.18
chr13_24218141_24218400	0.78	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	64751	0.12
chr1_244088089_244088421	0.78	AKT3	v-akt murine thymoma viral oncogene homolog 3	73874	0.11
chr9_139518377_139518866	0.77	ENSG00000252440	.	21654	0.09
chr4_96133826_96133977	0.77	BMPR1B	bone morphogenetic protein receptor, type IB	108395	0.08
chr10_82392995_82393146	0.76	SH2D4B	SH2 domain containing 4B	92495	0.08
chr3_114199378_114199529	0.76	ZBTB20	zinc finger and BTB domain containing 20	25789	0.23
chr6_124311673_124311824	0.76	RP11-374A22.1		167363	0.04
chr15_39705935_39706159	0.76	RP11-624L4.1		6863	0.3
chr8_135791564_135791765	0.76	ENSG00000207582	.	21186	0.21
chr8_8947011_8947181	0.76	ENSG00000239078	.	17070	0.15
chr15_90363455_90363606	0.76	ANPEP	alanyl (membrane) aminopeptidase	4897	0.14
chr14_56559878_56560064	0.76	ENSG00000221254	.	17773	0.19
chr2_60509602_60509838	0.75	ENSG00000200807	.	102020	0.08
chr11_73990200_73990857	0.75	ENSG00000206913	.	26931	0.14
chr9_94191030_94191181	0.75	NFIL3	nuclear factor, interleukin 3 regulated	4961	0.32
chr12_121763812_121763977	0.75	ANAPC5	anaphase promoting complex subunit 5	5300	0.22
chr17_28671646_28672042	0.75	ENSG00000207132	.	222	0.9
chr2_135187524_135187675	0.75	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	175769	0.03
chr8_8269357_8269508	0.74	SGK223	Tyrosine-protein kinase SgK223	25424	0.23
chr5_173367380_173367531	0.74	CPEB4	cytoplasmic polyadenylation element binding protein 4	47374	0.14
chr2_28032943_28033274	0.74	AC110084.1		23922	0.14
chr20_1062560_1062711	0.74	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	31271	0.18
chr20_19051967_19052205	0.74	ENSG00000264669	.	54343	0.15
chr19_6077071_6077284	0.74	CTC-232P5.3		9213	0.15
chr3_112091324_112091475	0.74	CD200	CD200 molecule	39374	0.18
chr13_28947990_28948191	0.74	FLT1	fms-related tyrosine kinase 1	27664	0.23
chr3_151038109_151038260	0.73	GPR87	G protein-coupled receptor 87	3444	0.21
chr12_4351047_4351203	0.73	CCND2	cyclin D2	31813	0.15
chr8_103907135_103907297	0.73	KB-1507C5.3		3112	0.22
chr10_125797103_125797288	0.73	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	9046	0.28
chr20_61303299_61303450	0.73	SLCO4A1	solute carrier organic anion transporter family, member 4A1	4209	0.14
chr6_170200363_170200514	0.73	RP1-266L20.9		29929	0.14
chr6_108514436_108514587	0.73	NR2E1	nuclear receptor subfamily 2, group E, member 1	24544	0.14
chr8_1843255_1843406	0.73	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	12508	0.24
chr18_61536702_61536853	0.72	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	2149	0.32
chr4_140046343_140046494	0.72	ELF2	E74-like factor 2 (ets domain transcription factor)	14188	0.16
chr16_58439523_58439674	0.72	GINS3	GINS complex subunit 3 (Psf3 homolog)	13300	0.13
chr4_74695065_74695238	0.72	CXCL6	chemokine (C-X-C motif) ligand 6	7063	0.17
chr5_145321914_145322065	0.72	SH3RF2	SH3 domain containing ring finger 2	4549	0.3
chr1_184758212_184758610	0.72	FAM129A	family with sequence similarity 129, member A	16708	0.19
chr14_75896920_75897204	0.71	JDP2	Jun dimerization protein 2	1775	0.33
chrX_147731034_147731185	0.71	AFF2	AF4/FMR2 family, member 2	69506	0.12
chr21_44809888_44810039	0.71	SIK1	salt-inducible kinase 1	37045	0.2
chr2_200604102_200604338	0.71	FTCDNL1	formiminotransferase cyclodeaminase N-terminal like	111376	0.07
chr8_117049336_117049537	0.71	ENSG00000199450	.	14432	0.29
chr5_17258380_17258531	0.71	ENSG00000252908	.	17735	0.19
chr3_182914292_182914491	0.70	LAMP3	lysosomal-associated membrane protein 3	32764	0.16
chr8_130501717_130501868	0.70	ENSG00000263763	.	5404	0.12
chr2_88360249_88360400	0.70	KRCC1	lysine-rich coiled-coil 1	5076	0.16
chr12_100527439_100527590	0.70	UHRF1BP1L	UHRF1 binding protein 1-like	9111	0.13
chr16_84409_84560	0.70	WASIR2	WASH and IL9R antisense RNA 2	11574	0.1
chr14_75754368_75754722	0.70	FOS	FBJ murine osteosarcoma viral oncogene homolog	7649	0.17
chr6_13295083_13295234	0.70	RP1-257A7.4		660	0.71
chr8_82061657_82061808	0.70	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	37429	0.2
chr17_2967826_2967977	0.69	OR1D5	olfactory receptor, family 1, subfamily D, member 5	1000	0.55
chr16_4853901_4854120	0.69	ROGDI	rogdi homolog (Drosophila)	1059	0.35
chr2_42891265_42891416	0.69	ENSG00000194270	.	26239	0.19
chr6_13467628_13468092	0.69	AL583828.1		18555	0.15
chr1_158781291_158781442	0.69	MNDA	myeloid cell nuclear differentiation antigen	19741	0.15
chr3_171852887_171853593	0.69	FNDC3B	fibronectin type III domain containing 3B	8476	0.29
chr7_127591875_127592026	0.69	SND1	staphylococcal nuclease and tudor domain containing 1	63985	0.12
chr3_3760202_3760353	0.69	ENSG00000223036	.	72137	0.12
chr6_36819266_36819870	0.69	CPNE5	copine V	11790	0.17
chr19_11116853_11117004	0.69	ENSG00000266352	.	5456	0.15
chr13_72430784_72430935	0.68	DACH1	dachshund homolog 1 (Drosophila)	10048	0.32
chr11_33895453_33895604	0.68	LMO2	LIM domain only 2 (rhombotin-like 1)	4166	0.23
chr1_185406296_185406447	0.68	ENSG00000252407	.	2995	0.36
chr7_28232792_28233167	0.68	JAZF1	JAZF zinc finger 1	12617	0.21
chr6_135515125_135515276	0.68	MYB-AS1	MYB antisense RNA 1	1933	0.32
chr18_60128145_60128323	0.68	ZCCHC2	zinc finger, CCHC domain containing 2	62006	0.12
chr22_24912227_24912606	0.68	AP000355.2		60	0.96
chr19_15755274_15755425	0.68	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	3230	0.23
chr6_158136852_158137003	0.68	SNX9	sorting nexin 9	107369	0.06
chr12_111039864_111040015	0.68	TCTN1	tectonic family member 1	11893	0.14
chr7_75585911_75586062	0.68	POR	P450 (cytochrome) oxidoreductase	2592	0.24
chr17_58471547_58471698	0.67	C17orf64	chromosome 17 open reading frame 64	1832	0.31
chr5_90437701_90437987	0.67	ENSG00000199643	.	128700	0.06
chrX_109279568_109279992	0.67	ENSG00000208013	.	18777	0.2
chr12_57894344_57894640	0.67	MARS	methionyl-tRNA synthetase	351	0.7
chr1_220967302_220967453	0.67	MARC1	mitochondrial amidoxime reducing component 1	2544	0.28
chr6_37940843_37941265	0.67	ZFAND3	zinc finger, AN1-type domain 3	43319	0.17
chr5_17234622_17234773	0.67	ENSG00000252908	.	6023	0.2
chrX_124543204_124543355	0.67	ENSG00000263886	.	121654	0.07
chr6_135516042_135516227	0.66	MYB-AS1	MYB antisense RNA 1	999	0.54
chr6_1911781_1912040	0.66	GMDS	GDP-mannose 4,6-dehydratase	264315	0.02
chr20_8456876_8457048	0.66	ENSG00000221201	.	132865	0.05
chr11_111340139_111340290	0.66	RP11-794P6.2	Uncharacterized protein	18150	0.1
chr21_38623377_38623560	0.66	DSCR3	Down syndrome critical region gene 3	16155	0.15
chr11_62574089_62574497	0.66	NXF1	nuclear RNA export factor 1	519	0.44
chr3_190327477_190327782	0.66	IL1RAP	interleukin 1 receptor accessory protein	5468	0.27
chr5_64248816_64248967	0.66	ENSG00000207439	.	170305	0.03
chr3_126247845_126247996	0.66	CHST13	carbohydrate (chondroitin 4) sulfotransferase 13	4794	0.16
chr15_91794688_91794839	0.66	SV2B	synaptic vesicle glycoprotein 2B	25663	0.24
chr8_74242566_74242717	0.66	RP11-434I12.2		14797	0.2
chr7_129338898_129339049	0.66	NRF1	nuclear respiratory factor 1	41782	0.13
chr8_61764995_61765146	0.65	RP11-33I11.2		42905	0.2
chr12_8608653_8608804	0.65	CLEC6A	C-type lectin domain family 6, member A	206	0.93
chr12_121867599_121867750	0.65	RNF34	ring finger protein 34, E3 ubiquitin protein ligase	20396	0.19
chr8_130968055_130968326	0.65	FAM49B	family with sequence similarity 49, member B	15028	0.2
chr20_3979711_3979862	0.65	RNF24	ring finger protein 24	16250	0.2
chr12_10285079_10285362	0.65	CLEC7A	C-type lectin domain family 7, member A	2364	0.21
chr21_45231884_45232124	0.65	AP001053.11		444	0.8
chr10_79315415_79315652	0.65	ENSG00000199592	.	31274	0.22
chr22_49098532_49098735	0.65	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	9574	0.28
chr13_53607499_53607650	0.65	OLFM4	olfactomedin 4	4680	0.34
chr2_204514643_204514794	0.65	CD28	CD28 molecule	56480	0.14
chr2_179590162_179590313	0.65	RP11-171I2.1		2053	0.28
chr1_182097721_182097872	0.64	ZNF648	zinc finger protein 648	66949	0.14
chr3_37965337_37965488	0.64	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	40658	0.12
chr22_37428904_37429055	0.64	MPST	mercaptopyruvate sulfurtransferase	9901	0.1
chr11_64114767_64114921	0.64	CCDC88B	coiled-coil domain containing 88B	1459	0.2
chr12_89728661_89728921	0.64	DUSP6	dual specificity phosphatase 6	16157	0.24
chrX_43752171_43752322	0.64	MAOB	monoamine oxidase B	10553	0.26
chr15_78300256_78300524	0.64	TBC1D2B	TBC1 domain family, member 2B	6364	0.14
chr17_58008197_58008348	0.64	RP11-178C3.1	Uncharacterized protein	9997	0.14
chr5_76155625_76155844	0.64	S100Z	S100 calcium binding protein Z	9810	0.17
chr4_12125618_12125813	0.64	ENSG00000266669	.	110650	0.08
chr2_176328710_176328962	0.64	ENSG00000221347	.	133735	0.05
chr3_37534685_37535118	0.64	ITGA9	integrin, alpha 9	41291	0.16
chr12_99012989_99013140	0.63	ENSG00000221625	.	13412	0.13
chr2_64447057_64447208	0.63	AC074289.1		7863	0.27
chr6_54082051_54082202	0.63	TINAG	tubulointerstitial nephritis antigen	90638	0.08
chr16_72909394_72909957	0.63	ENSG00000251868	.	53784	0.12
chr18_54111294_54111678	0.63	TXNL1	thioredoxin-like 1	170236	0.04
chr9_96541250_96541401	0.63	ENSG00000265347	.	40314	0.19
chr15_101375103_101375254	0.63	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	42741	0.16
chr18_434239_434644	0.63	RP11-720L2.2		10025	0.23
chr1_244052129_244052280	0.63	AKT3	v-akt murine thymoma viral oncogene homolog 3	37823	0.19
chr17_48259137_48259288	0.62	SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	13329	0.1
chr3_73025795_73025946	0.62	PPP4R2	protein phosphatase 4, regulatory subunit 2	20066	0.17
chr2_42552305_42552456	0.62	EML4	echinoderm microtubule associated protein like 4	23987	0.2
chr3_156305584_156305735	0.62	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	32686	0.18
chr3_151607143_151607294	0.62	SUCNR1	succinate receptor 1	15787	0.22
chr2_60594695_60594846	0.62	ENSG00000200807	.	16970	0.22
chr10_115967791_115967942	0.62	TDRD1	tudor domain containing 1	28517	0.14
chr10_28794304_28794638	0.62	WAC-AS1	WAC antisense RNA 1 (head to head)	26812	0.17
chr11_75602351_75602502	0.62	UVRAG	UV radiation resistance associated	12978	0.14
chr13_77207997_77208148	0.62	KCTD12	potassium channel tetramerization domain containing 12	252453	0.02
chr3_149167518_149167699	0.62	TM4SF4	transmembrane 4 L six family member 4	24153	0.18
chr5_171196803_171197257	0.61	ENSG00000264303	.	504	0.79
chr10_16784736_16784887	0.61	RP11-197M22.2		5565	0.3
chr10_101126561_101126712	0.61	CNNM1	cyclin M1	36948	0.18
chr2_106527446_106527597	0.61	AC009505.2		53888	0.15
chr17_14576158_14576427	0.61	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	371892	0.01
chr8_74399353_74399504	0.61	STAU2	staufen double-stranded RNA binding protein 2	95637	0.08
chr9_129183170_129183321	0.61	ENSG00000252985	.	5927	0.21
chr1_76689269_76689420	0.61	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	148940	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.2	0.5	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101)
0.1	0.5	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.6	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.5	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.5	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.3	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.1	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	1.7	GO:0050832	defense response to fungus(GO:0050832)
0.1	0.6	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.5	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0001820	serotonin secretion(GO:0001820)
0.1	0.4	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.5	GO:0045116	protein neddylation(GO:0045116)
0.1	0.3	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1	0.3	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.1	0.3	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.3	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.3	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.3	GO:0045924	regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.1	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.1	GO:0019530	taurine metabolic process(GO:0019530)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.1	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.2	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1	0.6	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	0.1	GO:0001878	response to yeast(GO:0001878)
0.1	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.2	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.1	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.1	0.2	GO:0034405	response to fluid shear stress(GO:0034405)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.2	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.4	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.3	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.5	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.0	0.2	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.4	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.2	GO:0045217	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0052308	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.2	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.2	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.5	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.3	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.2	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0008614	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.2	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.3	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0006837	serotonin transport(GO:0006837)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.2	GO:1902622	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.2	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.5	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.2	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.1	GO:0090494	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.4	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.5	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:1902931	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) negative regulation of alcohol biosynthetic process(GO:1902931)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0072124	glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.2	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.0	GO:0042537	benzene-containing compound metabolic process(GO:0042537)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.9	GO:0007623	circadian rhythm(GO:0007623)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0052803	histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0	0.2	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0	0.6	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0042116	macrophage activation(GO:0042116)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0046133	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0019935	cyclic-nucleotide-mediated signaling(GO:0019935)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.1	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0003097	renal water transport(GO:0003097)
0.0	0.0	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.0	0.1	GO:0042436	tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.3	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.0	0.1	GO:1902099	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.1	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.4	GO:1901799	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.0	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.3	GO:0043297	apical junction assembly(GO:0043297)
0.0	0.0	GO:1904478	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.1	GO:0033047	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) regulation of mitotic sister chromatid segregation(GO:0033047) metaphase/anaphase transition of cell cycle(GO:0044784) mitotic sister chromatid separation(GO:0051306)
0.0	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.2	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.3	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.0	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.2	GO:0019400	alditol metabolic process(GO:0019400)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.0	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.1	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.3	GO:0042552	myelination(GO:0042552)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.1	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.2	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.6	GO:0030315	T-tubule(GO:0030315)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.3	GO:0005682	U5 snRNP(GO:0005682)
0.1	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.4	GO:0043205	fibril(GO:0043205)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.4	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.3	GO:0045178	basal part of cell(GO:0045178)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0005902	microvillus(GO:0005902)
0.0	0.0	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.5	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.5	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.4	GO:0036064	ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.2	0.5	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.5	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.1	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.3	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.5	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.4	GO:0043559	insulin binding(GO:0043559)
0.1	0.7	GO:0019864	IgG binding(GO:0019864)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.2	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	0.5	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.3	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.5	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	0.3	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.2	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.7	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	0.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.4	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	1.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.6	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.3	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.3	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.6	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.8	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.4	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.2	GO:0015295	solute:proton symporter activity(GO:0015295)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.9	GO:0019825	oxygen binding(GO:0019825)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.3	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0050308	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	0.0	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.4	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	1.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.3	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.0	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.7	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.0	ST ADRENERGIC	Adrenergic Pathway
0.0	0.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	2.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	1.6	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.0	0.2	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions