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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CEBPE_CEBPD

Z-value: 4.41

Motif logo

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Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
ENSG00000092067.5 CEBPE
ENSG00000221869.4 CEBPD

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
CEBPDchr8_48647056_4864725044950.2074370.703.7e-02Click!
CEBPDchr8_48647408_4864769440970.2138810.571.1e-01Click!
CEBPDchr8_48647742_4864789338310.2191760.511.6e-01Click!
CEBPDchr8_48649354_4864950522190.291953-0.472.0e-01Click!
CEBPDchr8_48649526_4864967720470.308731-0.462.1e-01Click!
CEBPEchr14_23599806_23600030110930.0988220.924.8e-04Click!
CEBPEchr14_23584425_2358457643250.1167110.835.9e-03Click!
CEBPEchr14_23582041_2358226966700.1034020.817.9e-03Click!
CEBPEchr14_23598742_2359889399920.1002310.761.7e-02Click!
CEBPEchr14_23582556_2358277161620.1052570.761.8e-02Click!

Activity of the CEBPE_CEBPD motif across conditions

Conditions sorted by the z-value of the CEBPE_CEBPD motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_124201652_124202095 2.71 ZNF608
zinc finger protein 608
117373
0.06
chr1_234755566_234755985 2.68 IRF2BP2
interferon regulatory factor 2 binding protein 2
10504
0.19
chr12_48163883_48164256 2.49 RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
748
0.49
chr3_159547262_159547668 2.45 ENSG00000264146
.
6981
0.18
chr17_32641049_32641565 2.42 CCL8
chemokine (C-C motif) ligand 8
4748
0.16
chr1_232840317_232840703 2.34 ENSG00000238382
.
4560
0.32
chr2_172380569_172381265 2.27 CYBRD1
cytochrome b reductase 1
1328
0.53
chr2_174889480_174890119 2.07 SP3
Sp3 transcription factor
59369
0.15
chr6_15063091_15063325 2.07 ENSG00000242989
.
49991
0.17
chr6_125204297_125204713 2.06 RNF217
ring finger protein 217
79186
0.11
chr1_27425346_27425645 2.04 SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
55478
0.1
chr4_74570427_74570578 2.03 IL8
interleukin 8
35721
0.18
chr5_135347652_135347946 1.98 TGFBI
transforming growth factor, beta-induced, 68kDa
16785
0.2
chr20_52235971_52236462 1.94 ZNF217
zinc finger protein 217
10785
0.21
chr4_109993736_109993947 1.88 COL25A1
collagen, type XXV, alpha 1
229682
0.02
chr19_18788699_18789106 1.88 CRTC1
CREB regulated transcription coactivator 1
5585
0.15
chr2_69391215_69391505 1.87 ENSG00000251850
.
17775
0.18
chr16_4103086_4103844 1.82 RP11-462G12.4

21452
0.2
chr13_36297154_36297364 1.81 NBEA
neurobeachin
130116
0.05
chr12_6335659_6335810 1.81 ENSG00000202318
.
7887
0.18
chr10_104364228_104364579 1.80 ENSG00000207029
.
13122
0.16
chr6_11207055_11207535 1.80 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
25596
0.18
chr12_57542255_57543089 1.76 RP11-545N8.3

1270
0.29
chr13_80540246_80540397 1.72 SPRY2
sprouty homolog 2 (Drosophila)
373473
0.01
chr8_99248451_99248632 1.72 ENSG00000252558
.
44000
0.14
chr22_46994952_46995187 1.70 GRAMD4
GRAM domain containing 4
21230
0.2
chr4_157819489_157819815 1.68 PDGFC
platelet derived growth factor C
48228
0.15
chr1_15485504_15485655 1.68 TMEM51
transmembrane protein 51
5294
0.23
chr12_8043408_8043946 1.66 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
67
0.95
chr6_152279593_152279852 1.62 ESR1
estrogen receptor 1
77930
0.11
chr2_38405300_38405534 1.61 ENSG00000199603
.
30860
0.19
chr3_98503628_98503782 1.61 ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
13806
0.18
chr11_33981495_33981838 1.61 LMO2
LIM domain only 2 (rhombotin-like 1)
67830
0.1
chr8_126245222_126245373 1.61 ENSG00000242170
.
37549
0.19
chr7_116211652_116211947 1.59 AC006159.4

511
0.78
chr6_127514210_127514472 1.58 RNF146
ring finger protein 146
73414
0.11
chr18_363671_363972 1.58 RP11-720L2.2

60595
0.12
chr8_29682520_29682723 1.57 ENSG00000221003
.
103500
0.07
chr5_172879148_172879299 1.56 ENSG00000199219
.
89980
0.08
chr4_38077270_38077549 1.56 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
29917
0.24
chr5_159525036_159525187 1.54 PWWP2A
PWWP domain containing 2A
21318
0.17
chr18_457195_458136 1.52 RP11-720L2.2

33249
0.16
chr1_56981658_56981809 1.51 PPAP2B
phosphatidic acid phosphatase type 2B
63508
0.14
chr1_55742839_55743088 1.50 ENSG00000265822
.
51649
0.14
chr12_89778302_89778497 1.46 DUSP6
dual specificity phosphatase 6
31351
0.2
chr12_1427689_1428011 1.46 RP5-951N9.2

67149
0.11
chr12_7709559_7709800 1.45 CD163
CD163 molecule
53190
0.12
chr7_47826094_47826276 1.44 C7orf69
chromosome 7 open reading frame 69
8704
0.2
chr5_52319806_52319957 1.43 CTD-2175A23.1

33773
0.16
chr12_65701995_65702560 1.41 MSRB3
methionine sulfoxide reductase B3
18378
0.22
chr20_20761275_20761512 1.41 ENSG00000264361
.
42019
0.19
chr5_14880412_14880563 1.40 ANKH
ANKH inorganic pyrophosphate transport regulator
8600
0.23
chr11_1320455_1320759 1.39 TOLLIP
toll interacting protein
3413
0.18
chr2_196440572_196441282 1.39 SLC39A10
solute carrier family 39 (zinc transporter), member 10
226
0.96
chr14_31698873_31699173 1.39 ENSG00000202402
.
14944
0.14
chr14_69066045_69066553 1.39 CTD-2325P2.4

28863
0.22
chr5_176966509_176966660 1.38 FAM193B
family with sequence similarity 193, member B
232
0.88
chr2_208734859_208735279 1.38 AC083900.1

430
0.86
chr5_124299459_124299610 1.38 ZNF608
zinc finger protein 608
215034
0.02
chr8_96705142_96705479 1.37 ENSG00000223297
.
14167
0.29
chr5_171372243_171372394 1.37 FBXW11
F-box and WD repeat domain containing 11
32442
0.21
chr16_53809610_53810340 1.36 FTO
fat mass and obesity associated
71881
0.11
chr9_35526012_35526444 1.36 RUSC2
RUN and SH3 domain containing 2
12401
0.15
chr2_216765021_216765281 1.36 ENSG00000212055
.
21509
0.25
chr2_44335269_44335421 1.35 ENSG00000252599
.
46689
0.13
chr15_67094989_67095410 1.34 SMAD6
SMAD family member 6
91164
0.08
chr15_58540473_58540733 1.34 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
30859
0.22
chr15_51495837_51496055 1.34 CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
11475
0.2
chr3_66515065_66515261 1.33 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
36193
0.22
chr12_52348599_52348975 1.32 ACVR1B
activin A receptor, type IB
1623
0.31
chr10_71199738_71200040 1.32 TSPAN15
tetraspanin 15
11340
0.19
chr18_74277839_74277990 1.31 LINC00908
long intergenic non-protein coding RNA 908
37040
0.17
chr12_89555329_89555814 1.31 ENSG00000238302
.
120491
0.06
chr9_118758612_118758908 1.29 PAPPA
pregnancy-associated plasma protein A, pappalysin 1
157323
0.04
chr7_17409818_17409969 1.29 ENSG00000199473
.
3057
0.35
chr13_21643652_21643881 1.27 LATS2
large tumor suppressor kinase 2
8080
0.16
chr3_14160303_14160454 1.27 CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
5980
0.17
chr2_207858756_207859041 1.27 CPO
carboxypeptidase O
54620
0.14
chr5_14209039_14209227 1.26 TRIO
trio Rho guanine nucleotide exchange factor
25226
0.28
chr8_120627584_120627769 1.26 ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
22428
0.24
chr11_116855446_116855862 1.26 SIK3
SIK family kinase 3
27894
0.13
chr15_82421155_82421422 1.25 RP11-597K23.2
Uncharacterized protein
40256
0.14
chr5_142541616_142541862 1.24 ARHGAP26-IT1
ARHGAP26 intronic transcript 1 (non-protein coding)
30326
0.21
chr4_114867775_114867926 1.24 RP11-26P13.2

3438
0.33
chr14_33029435_33029586 1.24 AKAP6
A kinase (PRKA) anchor protein 6
65232
0.14
chr2_204416743_204416894 1.24 RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
16685
0.27
chr3_45451587_45451756 1.22 LARS2
leucyl-tRNA synthetase 2, mitochondrial
21560
0.23
chr6_20573217_20573464 1.22 CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
26768
0.21
chr7_101467071_101467370 1.21 CTA-339C12.1

789
0.68
chr8_22859230_22859412 1.21 PEBP4
phosphatidylethanolamine-binding protein 4
1808
0.22
chr2_216484884_216485080 1.21 AC012462.1

184006
0.03
chr7_157197600_157197914 1.20 DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
65242
0.11
chr2_146440332_146440602 1.20 ENSG00000253036
.
347829
0.01
chr9_124134798_124134949 1.19 STOM
stomatin
2342
0.23
chr8_127910617_127910864 1.18 ENSG00000212451
.
226973
0.02
chr12_32268115_32268884 1.16 RP11-843B15.2

8037
0.23
chr15_52390595_52390746 1.16 CTD-2184D3.5

2050
0.26
chr18_9779671_9779877 1.16 ENSG00000242651
.
50850
0.12
chr3_135218391_135218542 1.15 ENSG00000253004
.
300156
0.01
chr8_128755662_128755813 1.15 MYC
v-myc avian myelocytomatosis viral oncogene homolog
7260
0.28
chr7_157194160_157194456 1.15 DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
61793
0.12
chr7_80477310_80477461 1.15 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
71114
0.13
chr18_18744847_18745057 1.14 ENSG00000251886
.
44485
0.15
chr18_43381353_43381623 1.14 SIGLEC15
sialic acid binding Ig-like lectin 15
23989
0.18
chr10_95196634_95196984 1.14 MYOF
myoferlin
45142
0.14
chr5_115374031_115374427 1.13 ENSG00000220996
.
4729
0.15
chr11_2000243_2000455 1.13 MRPL23-AS1
MRPL23 antisense RNA 1
10801
0.13
chr8_126323786_126323944 1.12 RP11-550A5.2

39793
0.16
chr21_15957589_15957802 1.12 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
1972
0.34
chr17_25867570_25867824 1.11 KSR1
kinase suppressor of ras 1
42250
0.14
chr8_119073040_119073274 1.10 EXT1
exostosin glycosyltransferase 1
49496
0.2
chr5_36373610_36373761 1.10 RANBP3L
RAN binding protein 3-like
71469
0.11
chr1_206165257_206165565 1.09 FAM72A
family with sequence similarity 72, member A
26500
0.15
chr2_103104222_103104645 1.09 SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
14671
0.18
chr2_129492797_129493141 1.09 ENSG00000238379
.
290197
0.01
chr4_38602938_38603142 1.09 RP11-617D20.1

23156
0.2
chr7_115671683_115671834 1.09 TFEC
transcription factor EC
891
0.74
chr9_79206598_79206788 1.08 ENSG00000241781
.
19962
0.22
chr16_69213504_69213973 1.08 ENSG00000207083
.
4058
0.14
chr12_27242184_27242645 1.08 C12orf71
chromosome 12 open reading frame 71
6967
0.23
chr12_106683073_106683224 1.07 ENSG00000238609
.
6381
0.18
chr8_105429764_105429988 1.07 ENSG00000222158
.
7711
0.18
chr12_110783040_110783191 1.07 ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
891
0.57
chr1_202827568_202827814 1.06 RP11-480I12.5

536
0.68
chr4_143738912_143739452 1.06 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
28261
0.27
chr2_28940215_28940366 1.06 AC097724.3

18685
0.15
chr7_106059873_106060161 1.05 CTB-111H14.1

85268
0.09
chr17_60772153_60772304 1.05 RP11-156L14.1

4377
0.18
chr3_99827675_99827826 1.05 FILIP1L
filamin A interacting protein 1-like
5607
0.21
chr2_41945950_41946101 1.04 ENSG00000252281
.
15492
0.27
chr3_4753831_4754047 1.03 ENSG00000239126
.
166447
0.03
chr1_203037933_203038268 1.03 PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
15226
0.12
chr17_25816336_25816487 1.03 KSR1
kinase suppressor of ras 1
17375
0.19
chr4_62138914_62139065 1.03 LPHN3
latrophilin 3
71129
0.14
chr9_38046646_38046797 1.03 SHB
Src homology 2 domain containing adaptor protein B
22487
0.23
chr11_12088585_12089097 1.03 MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
26702
0.22
chr21_40386888_40387293 1.03 ENSG00000272015
.
120381
0.05
chr2_99422021_99422172 1.03 ENSG00000201070
.
23223
0.18
chrX_24073482_24074722 1.02 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
1014
0.57
chr5_108065156_108065307 1.02 FER
fer (fps/fes related) tyrosine kinase
18292
0.28
chr2_188418233_188418384 1.02 AC007319.1

568
0.57
chr1_192874230_192874411 1.01 ENSG00000223075
.
29205
0.2
chr20_2967189_2967462 1.00 GNRH2
gonadotropin-releasing hormone 2
56943
0.08
chr11_130153287_130153576 1.00 ZBTB44
zinc finger and BTB domain containing 44
21647
0.2
chr1_16212220_16212786 0.99 SPEN
spen family transcriptional repressor
9432
0.15
chr8_26465978_26466617 0.99 DPYSL2
dihydropyrimidinase-like 2
30376
0.22
chr5_119594026_119594293 0.99 ENSG00000251975
.
79189
0.12
chr7_77425841_77426956 0.99 TMEM60
transmembrane protein 60
1499
0.34
chr1_8107712_8107948 0.98 ERRFI1
ERBB receptor feedback inhibitor 1
21462
0.2
chr12_62642816_62642967 0.98 FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
9713
0.21
chr1_41326111_41326598 0.98 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
1664
0.31
chr20_10944386_10944681 0.98 RP11-103J8.1

22790
0.25
chr8_25045009_25045650 0.97 DOCK5
dedicator of cytokinesis 5
2949
0.31
chr2_29289311_29289462 0.97 C2orf71
chromosome 2 open reading frame 71
7741
0.15
chr13_75989940_75990220 0.97 TBC1D4-AS1
TBC1D4 antisense RNA 1
38650
0.18
chr15_50187660_50187811 0.97 ATP8B4
ATPase, class I, type 8B, member 4
12555
0.22
chr2_219671233_219671384 0.97 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
671
0.62
chr8_122176471_122176664 0.96 ENSG00000221644
.
22565
0.27
chr14_21153240_21153447 0.96 RNASE4
ribonuclease, RNase A family, 4
525
0.38
chr12_50965671_50966306 0.95 ENSG00000207136
.
61068
0.1
chr1_48027881_48028032 0.95 ENSG00000221447
.
58893
0.12
chr13_47207440_47207736 0.95 LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
46383
0.18
chr2_16514373_16514524 0.94 ENSG00000251704
.
133977
0.05
chr5_112030956_112031107 0.94 APC
adenomatous polyposis coli
12164
0.26
chr1_57955256_57955407 0.94 DAB1
Dab, reelin signal transducer, homolog 1 (Drosophila)
65602
0.15
chr2_152945747_152946000 0.94 AC079790.2

8969
0.23
chr20_61469350_61469501 0.94 COL9A3
collagen, type IX, alpha 3
20262
0.11
chr2_113597075_113597265 0.94 IL1B
interleukin 1, beta
2690
0.24
chr21_30609945_30610281 0.93 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
43645
0.11
chr8_116685532_116685824 0.93 TRPS1
trichorhinophalangeal syndrome I
3968
0.38
chr3_171528829_171529427 0.93 PLD1
phospholipase D1, phosphatidylcholine-specific
844
0.52
chrX_71796506_71796773 0.93 HDAC8
histone deacetylase 8
3686
0.31
chr12_66289441_66289878 0.93 RP11-366L20.2
Uncharacterized protein
13712
0.17
chr3_124500151_124500305 0.93 ITGB5-AS1
ITGB5 antisense RNA 1
226
0.93
chr6_74276834_74277097 0.93 RP11-505P4.7

43401
0.1
chr17_62843312_62843537 0.93 PLEKHM1P
pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
10181
0.12
chr4_158924332_158924650 0.92 FAM198B
family with sequence similarity 198, member B
156342
0.04
chr10_72746069_72746220 0.92 PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
97603
0.07
chr12_11899426_11899590 0.92 ETV6
ets variant 6
5927
0.32
chr1_65663976_65664276 0.92 AK4
adenylate kinase 4
50240
0.13
chr1_42627613_42628057 0.92 GUCA2A
guanylate cyclase activator 2A (guanylin)
2554
0.29
chr2_32118260_32118422 0.92 ENSG00000221326
.
26677
0.18
chr12_121158667_121159015 0.91 ENSG00000265455
.
2155
0.16
chr7_20434869_20435036 0.91 ENSG00000200753
.
17998
0.23
chr8_124194465_124194779 0.91 FAM83A
family with sequence similarity 83, member A
130
0.77
chr12_123166281_123166585 0.91 HCAR2
hydroxycarboxylic acid receptor 2
21457
0.14
chr2_187752008_187752159 0.91 ZSWIM2
zinc finger, SWIM-type containing 2
38186
0.21
chr3_150864378_150864529 0.91 ENSG00000199994
.
41433
0.13
chr6_33588468_33588675 0.91 ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
429
0.78
chr12_32527225_32527490 0.91 ENSG00000207176
.
21724
0.19
chr12_70748301_70748911 0.91 KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
11450
0.21
chr15_64509004_64509155 0.90 PPIB
peptidylprolyl isomerase B (cyclophilin B)
53675
0.1
chr5_163391136_163391287 0.90 ENSG00000251998
.
168040
0.04
chr5_95460533_95460684 0.90 ENSG00000207578
.
45766
0.17
chr21_35917342_35917640 0.90 RCAN1
regulator of calcineurin 1
14986
0.2
chr14_31697937_31698088 0.90 ENSG00000202402
.
15955
0.14
chr4_15081864_15082159 0.90 ENSG00000199420
.
13707
0.24
chr10_114501840_114502050 0.90 RP11-25C19.3

64367
0.12
chr2_28939565_28939734 0.89 AC097724.3

19326
0.15
chr3_25593600_25593751 0.89 ENSG00000272166
.
3422
0.31

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 0.8 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 0.6 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.2 0.8 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.2 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.5 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.2 0.5 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 0.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.5 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.6 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.2 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.3 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.1 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.4 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 0.3 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.4 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.1 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.6 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.1 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.7 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.3 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.3 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.1 GO:0015840 urea transport(GO:0015840)
0.1 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.2 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.1 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.3 GO:0051135 regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.8 GO:0035329 hippo signaling(GO:0035329)
0.1 0.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.5 GO:0010042 response to manganese ion(GO:0010042)
0.1 0.2 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.1 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 1.4 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.1 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.1 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.1 GO:0032026 response to magnesium ion(GO:0032026)
0.1 0.2 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.2 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.5 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.4 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.3 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.5 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.6 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.1 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0035930 obsolete regulation of natriuresis(GO:0003078) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.2 GO:0060004 reflex(GO:0060004)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:1903727 positive regulation of phospholipid metabolic process(GO:1903727)
0.0 0.3 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.3 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.2 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.3 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.3 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0036315 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:1902622 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0 0.0 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.3 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.3 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.0 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.0 GO:0032914 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.0 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.7 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.3 GO:0006101 citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.0 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0048538 thymus development(GO:0048538)
0.0 0.0 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:1903726 regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
0.0 0.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0033004 negative regulation of mast cell activation(GO:0033004) negative regulation of action potential(GO:0045759)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.0 GO:0006949 syncytium formation(GO:0006949)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.0 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0048821 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0032309 icosanoid secretion(GO:0032309)
0.0 0.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.3 GO:0051318 G1 phase(GO:0051318)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.0 GO:0032892 positive regulation of organic acid transport(GO:0032892)
0.0 0.3 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.0 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.4 GO:0006821 chloride transport(GO:0006821)
0.0 0.0 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0051593 response to folic acid(GO:0051593)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0015844 monoamine transport(GO:0015844)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.0 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0000718 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 1.0 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:2001235 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.5 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0051955 regulation of amino acid transport(GO:0051955)
0.0 0.2 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.2 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 0.5 GO:0045298 tubulin complex(GO:0045298)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0001527 microfibril(GO:0001527)
0.1 0.3 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1 0.4 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.5 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0043205 fibril(GO:0043205)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.2 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.1 1.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.5 GO:0030315 T-tubule(GO:0030315)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 1.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.0 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.0 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.7 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0030426 growth cone(GO:0030426)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 3.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.0 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 1.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.9 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 1.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.2 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.1 0.4 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.3 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.5 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.4 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.1 0.3 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.8 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.2 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0046790 virion binding(GO:0046790)
0.1 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 2.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0015368 calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0033265 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 1.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0043176 amine binding(GO:0043176)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.3 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME APOPTOSIS Genes involved in Apoptosis
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling