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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for CPEB1

Z-value: 1.30

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Transcription factors associated with CPEB1

Gene Symbol Gene ID Gene Info
ENSG00000214575.5 cytoplasmic polyadenylation element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_83315771_83316117CPEB1700.8981150.901.0e-03Click!
chr15_83239391_83239542CPEB110430.414979-0.618.0e-02Click!
chr15_83240171_83240322CPEB12630.876035-0.531.4e-01Click!
chr15_83235277_83235428CPEB151570.136551-0.501.7e-01Click!
chr15_83241226_83241377CPEB14730.732689-0.442.3e-01Click!

Activity of the CPEB1 motif across conditions

Conditions sorted by the z-value of the CPEB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_99721349_99721548 0.31 AL109767.1

7837
0.22
chr17_37948646_37948906 0.29 IKZF3
IKAROS family zinc finger 3 (Aiolos)
14298
0.14
chr17_47896409_47896901 0.28 RP11-304F15.3

26617
0.12
chr10_22962552_22962703 0.28 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
40410
0.2
chr10_43843752_43843981 0.27 ENSG00000221468
.
6632
0.19
chr2_143888983_143889411 0.25 ARHGAP15
Rho GTPase activating protein 15
2314
0.39
chr20_56195788_56195967 0.24 ZBP1
Z-DNA binding protein 1
245
0.94
chr8_2166897_2167149 0.24 MYOM2
myomesin 2
173839
0.03
chr18_43808452_43808604 0.23 C18orf25
chromosome 18 open reading frame 25
54528
0.13
chr9_115066997_115067151 0.23 PTBP3
polypyrimidine tract binding protein 3
28049
0.14
chr17_33859475_33859650 0.23 SLFN12L
schlafen family member 12-like
5318
0.12
chr14_92435696_92435980 0.23 FBLN5
fibulin 5
21507
0.18
chr17_37934637_37934793 0.23 IKZF3
IKAROS family zinc finger 3 (Aiolos)
237
0.9
chr3_114749732_114749883 0.23 ZBTB20
zinc finger and BTB domain containing 20
40415
0.23
chr3_18597997_18598194 0.23 ENSG00000228956
.
29431
0.24
chr3_197595834_197596031 0.23 LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
2846
0.23
chr10_32749220_32749452 0.22 CCDC7
coiled-coil domain containing 7
8787
0.22
chr1_59144710_59144861 0.22 MYSM1
Myb-like, SWIRM and MPN domains 1
20979
0.2
chrX_78517963_78518114 0.22 GPR174
G protein-coupled receptor 174
91569
0.09
chr22_20919404_20919765 0.22 MED15
mediator complex subunit 15
14007
0.14
chr9_95733021_95733387 0.21 FGD3
FYVE, RhoGEF and PH domain containing 3
3560
0.27
chr14_35400951_35401102 0.21 ENSG00000199980
.
1723
0.34
chr11_108108099_108108300 0.21 ENSG00000206967
.
7868
0.16
chrX_53712364_53712515 0.21 HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
1234
0.59
chr3_151957728_151957952 0.21 MBNL1
muscleblind-like splicing regulator 1
27989
0.2
chr1_193428730_193429035 0.21 ENSG00000252241
.
272192
0.01
chr22_29195216_29195505 0.20 XBP1
X-box binding protein 1
761
0.48
chr6_89626872_89627052 0.20 RNGTT
RNA guanylyltransferase and 5'-phosphatase
46318
0.15
chr17_62140117_62140268 0.20 ICAM2
intercellular adhesion molecule 2
42198
0.11
chr14_99720519_99720759 0.20 AL109767.1

8646
0.22
chr2_12849849_12850137 0.20 TRIB2
tribbles pseudokinase 2
7022
0.27
chr2_238978929_238979080 0.20 SCLY
selenocysteine lyase
899
0.56
chr11_60767130_60767281 0.20 CD6
CD6 molecule
8801
0.13
chr2_202059112_202059539 0.19 CASP10
caspase 10, apoptosis-related cysteine peptidase
11407
0.15
chr6_36077167_36077664 0.19 MAPK13
mitogen-activated protein kinase 13
20683
0.16
chr11_5246485_5246763 0.19 ENSG00000221031
.
755
0.38
chr1_62188467_62188709 0.19 TM2D1
TM2 domain containing 1
2217
0.35
chr5_178978355_178978506 0.19 RUFY1
RUN and FYVE domain containing 1
591
0.74
chr16_9048805_9048966 0.19 USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
1352
0.47
chr4_40189463_40189614 0.18 RHOH
ras homolog family member H
3135
0.27
chr2_24272218_24272506 0.18 C2orf44
chromosome 2 open reading frame 44
83
0.67
chr14_99691163_99691558 0.18 AL109767.1

37925
0.16
chr2_106545238_106545692 0.18 AC009505.2

71832
0.11
chr14_99726600_99726784 0.18 AL109767.1

2593
0.31
chr2_177080_177288 0.17 AC079779.7

20385
0.21
chr1_203259066_203259291 0.17 BTG2
BTG family, member 2
15486
0.16
chr12_96755738_96755889 0.17 CDK17
cyclin-dependent kinase 17
26805
0.18
chr17_8147401_8147552 0.17 PFAS
phosphoribosylformylglycinamidine synthase
3460
0.11
chr1_101395582_101395733 0.17 SLC30A7
solute carrier family 30 (zinc transporter), member 7
31727
0.12
chr12_66684119_66684270 0.17 ENSG00000222744
.
2269
0.26
chr4_143635559_143635710 0.17 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
131809
0.06
chr14_61817217_61817623 0.17 PRKCH
protein kinase C, eta
2811
0.3
chr14_21697616_21697899 0.17 HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
1824
0.32
chr17_46670095_46670275 0.17 HOXB-AS3
HOXB cluster antisense RNA 3
503
0.48
chr12_42722388_42722539 0.16 PPHLN1
periphilin 1
2483
0.22
chr18_60970002_60970404 0.16 RP11-28F1.2

11112
0.18
chr3_60090466_60090753 0.16 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
133026
0.06
chr8_66769940_66770103 0.16 PDE7A
phosphodiesterase 7A
15834
0.27
chr7_8173692_8173968 0.16 AC006042.6

20175
0.19
chr18_67626079_67626351 0.16 CD226
CD226 molecule
1803
0.48
chr20_57734207_57734542 0.16 ZNF831
zinc finger protein 831
31701
0.19
chr3_133210635_133210930 0.16 BFSP2-AS1
BFSP2 antisense RNA 1
36162
0.16
chr5_56031061_56031244 0.16 MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
80249
0.09
chr18_3259945_3260096 0.16 RP13-270P17.1

1800
0.26
chr17_37925720_37925871 0.16 IKZF3
IKAROS family zinc finger 3 (Aiolos)
8683
0.13
chr3_33843113_33843264 0.16 PDCD6IP
programmed cell death 6 interacting protein
3073
0.38
chr7_12252889_12253205 0.16 TMEM106B
transmembrane protein 106B
2098
0.48
chr15_26078408_26078559 0.16 ENSG00000199214
.
15353
0.17
chr17_48965132_48965283 0.16 TOB1
transducer of ERBB2, 1
19868
0.15
chr14_99665484_99665650 0.16 AL162151.4

40814
0.17
chr2_204596528_204596679 0.16 CD28
CD28 molecule
25187
0.19
chr7_135347931_135348131 0.16 C7orf73
chromosome 7 open reading frame 73
762
0.59
chr16_67097233_67097384 0.16 CBFB
core-binding factor, beta subunit
33453
0.09
chr1_101396601_101396752 0.16 SLC30A7
solute carrier family 30 (zinc transporter), member 7
30708
0.13
chr2_38056365_38056516 0.16 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
90829
0.08
chr12_25536580_25536731 0.16 ENSG00000201439
.
20707
0.24
chr17_26206098_26206388 0.16 LYRM9
LYR motif containing 9
4080
0.19
chr5_54391771_54392054 0.16 GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
6564
0.16
chr3_33038134_33038326 0.16 CCR4
chemokine (C-C motif) receptor 4
45164
0.15
chr16_12006362_12006679 0.16 GSPT1
G1 to S phase transition 1
2540
0.15
chr14_98637494_98637668 0.16 ENSG00000222066
.
160506
0.04
chr6_112006099_112006376 0.16 FYN
FYN oncogene related to SRC, FGR, YES
35028
0.16
chr5_55391166_55391317 0.16 ANKRD55
ankyrin repeat domain 55
21537
0.16
chr5_148733548_148733699 0.16 GRPEL2-AS1
GRPEL2 atnisense RNA 1
3582
0.14
chr3_46411260_46411477 0.16 CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
265
0.9
chr1_8212069_8212240 0.15 ENSG00000200975
.
54503
0.13
chr13_40763533_40763684 0.15 ENSG00000207458
.
37356
0.23
chr17_71208357_71208949 0.15 COG1
component of oligomeric golgi complex 1
6355
0.15
chr2_204812325_204812548 0.15 ICOS
inducible T-cell co-stimulator
10933
0.28
chr6_111495332_111495527 0.15 SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
1531
0.44
chr12_9807704_9808028 0.15 RP11-705C15.2

1587
0.25
chr10_120458675_120458868 0.15 CACUL1
CDK2-associated, cullin domain 1
55987
0.12
chr4_143621409_143621560 0.15 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
139662
0.05
chr13_100194616_100194885 0.15 ENSG00000212197
.
6100
0.2
chr2_152144415_152144634 0.15 NMI
N-myc (and STAT) interactor
1884
0.36
chr6_151735099_151735250 0.15 ZBTB2
zinc finger and BTB domain containing 2
22491
0.13
chr22_22117730_22117960 0.15 YPEL1
yippee-like 1 (Drosophila)
27722
0.11
chr2_44796225_44796376 0.15 CAMKMT
calmodulin-lysine N-methyltransferase
196419
0.03
chr12_22484745_22484973 0.15 ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
2238
0.44
chr14_38546372_38546618 0.15 CTD-2058B24.2

13868
0.25
chr7_130596773_130597211 0.15 ENSG00000226380
.
34694
0.19
chr6_139485972_139486167 0.15 HECA
headcase homolog (Drosophila)
29820
0.2
chr2_10815541_10815692 0.15 NOL10
nucleolar protein 10
3800
0.22
chr6_502144_502346 0.15 RP1-20B11.2

21926
0.26
chr2_158746528_158746679 0.15 UPP2
uridine phosphorylase 2
13389
0.16
chr2_95741879_95742163 0.15 AC103563.9

23100
0.15
chr1_167458272_167458474 0.15 CD247
CD247 molecule
29402
0.16
chr22_40296066_40296492 0.15 GRAP2
GRB2-related adaptor protein 2
807
0.6
chrX_12972541_12972692 0.15 TMSB4X
thymosin beta 4, X-linked
20611
0.19
chr12_45269447_45269715 0.15 NELL2
NEL-like 2 (chicken)
14
0.98
chr4_82414160_82414311 0.15 RASGEF1B
RasGEF domain family, member 1B
21166
0.28
chr2_102186414_102186691 0.15 RFX8
RFX family member 8, lacking RFX DNA binding domain
95387
0.08
chr14_98665522_98665718 0.15 ENSG00000222066
.
132467
0.05
chr8_126940986_126941137 0.15 ENSG00000206695
.
27866
0.26
chrX_70763186_70763395 0.15 OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
6426
0.2
chr3_56912022_56912345 0.15 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
38316
0.18
chr11_133798697_133798899 0.15 IGSF9B
immunoglobulin superfamily, member 9B
17389
0.18
chr10_11252064_11252436 0.15 RP3-323N1.2

38911
0.17
chr6_143862532_143862683 0.15 PHACTR2
phosphatase and actin regulator 2
4625
0.18
chr17_33171161_33171312 0.15 CCT6B
chaperonin containing TCP1, subunit 6B (zeta 2)
117185
0.05
chr5_172425652_172425803 0.15 ATP6V0E1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
14893
0.14
chr2_7052046_7052272 0.14 RNF144A
ring finger protein 144A
5364
0.19
chr1_77774898_77775049 0.14 AK5
adenylate kinase 5
26209
0.18
chr1_111326257_111326605 0.14 ENSG00000199710
.
19303
0.2
chr11_117916276_117916450 0.14 ENSG00000272075
.
21589
0.14
chr1_184813678_184813906 0.14 ENSG00000252222
.
23169
0.2
chr11_35351604_35352020 0.14 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
28737
0.17
chr5_156953479_156953635 0.14 ADAM19
ADAM metallopeptidase domain 19
23727
0.15
chr5_39190224_39190381 0.14 FYB
FYN binding protein
12827
0.27
chr11_108084515_108084666 0.14 ATM
ataxia telangiectasia mutated
8621
0.16
chr3_151929579_151929730 0.14 MBNL1
muscleblind-like splicing regulator 1
56175
0.14
chr21_16893074_16893225 0.14 ENSG00000212564
.
93453
0.09
chr14_22621058_22621209 0.14 ENSG00000238634
.
10246
0.28
chr3_101832900_101833053 0.14 ZPLD1
zona pellucida-like domain containing 1
14888
0.29
chr13_42041149_42041395 0.14 RGCC
regulator of cell cycle
9577
0.16
chr1_121311422_121311588 0.14 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
375568
0.01
chr6_110882269_110882528 0.14 CDK19
cyclin-dependent kinase 19
82123
0.08
chr14_64329252_64329512 0.14 SYNE2
spectrin repeat containing, nuclear envelope 2
9650
0.22
chr3_195250896_195251062 0.14 ENSG00000252620
.
960
0.52
chr4_40236655_40236806 0.14 RHOH
ras homolog family member H
34766
0.17
chr1_93420237_93420388 0.14 FAM69A
family with sequence similarity 69, member A
6745
0.13
chr16_53530038_53530189 0.14 AKTIP
AKT interacting protein
4128
0.23
chr1_43500743_43500945 0.14 ENSG00000252803
.
11536
0.19
chr4_148972762_148973133 0.14 RP11-76G10.1

94675
0.09
chr5_14704726_14704885 0.14 FAM105B
family with sequence similarity 105, member B
23146
0.19
chr6_35649971_35650157 0.14 FKBP5
FK506 binding protein 5
6628
0.14
chr3_16356399_16356550 0.14 RP11-415F23.2

528
0.76
chr2_205836626_205836826 0.14 PARD3B
par-3 family cell polarity regulator beta
426003
0.01
chr17_37946299_37946450 0.14 IKZF3
IKAROS family zinc finger 3 (Aiolos)
11896
0.14
chr14_21136496_21136717 0.14 ENSG00000199461
.
10964
0.09
chr22_40730411_40730669 0.14 ADSL
adenylosuccinate lyase
11967
0.19
chr10_124175104_124175255 0.14 ENSG00000265442
.
1302
0.43
chr6_130505643_130505870 0.14 SAMD3
sterile alpha motif domain containing 3
29758
0.2
chr15_57857934_57858132 0.14 GCOM1
GRINL1A complex locus 1
26073
0.17
chr19_1057848_1057999 0.14 ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
990
0.32
chr14_102294369_102294541 0.14 CTD-2017C7.1

11413
0.15
chr3_15578936_15579113 0.14 COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
15766
0.14
chr7_129545877_129546028 0.14 UBE2H
ubiquitin-conjugating enzyme E2H
45215
0.1
chr13_27296341_27296492 0.14 GPR12
G protein-coupled receptor 12
38011
0.2
chr7_142504543_142504845 0.14 PRSS3P2
protease, serine, 3 pseudogene 2
23563
0.15
chr18_13297039_13297305 0.14 LDLRAD4
low density lipoprotein receptor class A domain containing 4
19070
0.18
chr1_153234965_153235116 0.14 LOR
loricrin
2864
0.19
chr6_110515654_110515805 0.14 CDC40
cell division cycle 40
14105
0.22
chr6_36932436_36932655 0.14 PI16
peptidase inhibitor 16
10336
0.17
chr4_143621654_143621881 0.14 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
139945
0.05
chr14_90105259_90105410 0.14 RP11-944C7.1
Protein LOC100506792
7424
0.15
chr12_45608916_45609133 0.14 ANO6
anoctamin 6
779
0.77
chr6_26358903_26359054 0.14 ENSG00000252399
.
5714
0.1
chr6_139492633_139492784 0.14 HECA
headcase homolog (Drosophila)
36459
0.17
chr14_106630342_106630519 0.14 IGHV1-17
immunoglobulin heavy variable 1-17 (pseudogene)
1019
0.19
chr17_46508666_46508817 0.14 SKAP1
src kinase associated phosphoprotein 1
1160
0.41
chr16_28998091_28998242 0.14 LAT
linker for activation of T cells
633
0.49
chr1_24839011_24839397 0.14 RCAN3
RCAN family member 3
1606
0.35
chr6_108109631_108109782 0.14 SCML4
sex comb on midleg-like 4 (Drosophila)
16251
0.26
chr16_67538677_67538891 0.14 FAM65A
family with sequence similarity 65, member A
13537
0.09
chr10_63809503_63809654 0.14 ARID5B
AT rich interactive domain 5B (MRF1-like)
608
0.82
chr10_90590706_90591168 0.14 ANKRD22
ankyrin repeat domain 22
20638
0.15
chr15_40743963_40744180 0.14 RP11-64K12.9

2767
0.14
chr10_14605059_14605230 0.14 FAM107B
family with sequence similarity 107, member B
6965
0.26
chr1_90077786_90078098 0.14 RP11-413E1.4

17342
0.16
chr5_80849712_80849863 0.14 SSBP2
single-stranded DNA binding protein 2
40251
0.21
chr4_110496140_110496528 0.13 CCDC109B
coiled-coil domain containing 109B
14188
0.22
chr10_6635069_6635386 0.13 PRKCQ
protein kinase C, theta
12964
0.3
chr2_95690474_95690625 0.13 MAL
mal, T-cell differentiation protein
880
0.49
chr15_75725504_75725655 0.13 SIN3A
SIN3 transcription regulator family member A
18347
0.15
chr8_101728028_101728286 0.13 PABPC1
poly(A) binding protein, cytoplasmic 1
1961
0.25
chr8_29389067_29389218 0.13 RP4-676L2.1

178455
0.03
chr17_76710387_76710538 0.13 CYTH1
cytohesin 1
2645
0.28
chr10_52380207_52380358 0.13 SGMS1
sphingomyelin synthase 1
3461
0.21
chr19_11085110_11085263 0.13 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
9642
0.13
chr1_7811961_7812165 0.13 CAMTA1
calmodulin binding transcription activator 1
7042
0.17
chr21_43827327_43827478 0.13 UBASH3A
ubiquitin associated and SH3 domain containing A
3376
0.17
chr20_52216616_52216767 0.13 ZNF217
zinc finger protein 217
6313
0.21
chr2_12641093_12641393 0.13 ENSG00000207183
.
89616
0.1
chr14_98606379_98606534 0.13 C14orf64
chromosome 14 open reading frame 64
161995
0.04
chr9_74375544_74375695 0.13 TMEM2
transmembrane protein 2
7683
0.3
chr5_54399188_54399417 0.13 GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
826
0.55
chr5_118574777_118574928 0.13 ENSG00000266587
.
18280
0.18
chr5_49931517_49931668 0.13 PARP8
poly (ADP-ribose) polymerase family, member 8
30141
0.26
chr1_100856626_100856777 0.13 ENSG00000216067
.
12370
0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CPEB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.2 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.1 0.2 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.1 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.2 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0002363 alpha-beta T cell lineage commitment(GO:0002363)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.2 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 1.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0033083 regulation of immature T cell proliferation(GO:0033083) regulation of immature T cell proliferation in thymus(GO:0033084)
0.0 0.0 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.0 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0002704 negative regulation of leukocyte mediated immunity(GO:0002704)
0.0 0.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.0 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.0 GO:0051299 centrosome separation(GO:0051299)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152) anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.6 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle