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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for CREB1

Z-value: 0.64

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Transcription factors associated with CREB1

Gene Symbol	Gene ID	Gene Info
CREB1 Ensembl NCBI GeneCards UniProt	ENSG00000118260.10	cAMP responsive element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_208394003_208394154	CREB1	383	0.525119	0.75	1.9e-02	Click!
chr2_208396639_208396800	CREB1	1891	0.318398	0.73	2.6e-02	Click!
chr2_208413656_208413807	CREB1	1254	0.492185	-0.69	3.8e-02	Click!
chr2_208421027_208421178	CREB1	2744	0.288571	-0.67	5.1e-02	Click!
chr2_208411969_208412295	CREB1	2853	0.282219	-0.65	5.6e-02	Click!

Activity of the CREB1 motif across conditions

Conditions sorted by the z-value of the CREB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_40014894_40015175	0.40	BCOR	BCL6 corepressor	9152	0.31
chr18_77138968_77139119	0.31	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	16813	0.2
chr22_41681891_41682042	0.30	RANGAP1	Ran GTPase activating protein 1	3	0.96
chr1_27191187_27191395	0.30	SFN	stratifin	1658	0.22
chr12_54145261_54145434	0.29	CALCOCO1	calcium binding and coiled-coil domain 1	23818	0.14
chr11_133907189_133907404	0.22	JAM3	junctional adhesion molecule 3	31524	0.18
chr2_216877823_216877974	0.21	MREG	melanoregulin	448	0.87
chr13_42615279_42615552	0.20	DGKH	diacylglycerol kinase, eta	1239	0.48
chr3_32022334_32022485	0.20	OSBPL10	oxysterol binding protein-like 10	383	0.73
chr1_64059758_64059909	0.19	PGM1	phosphoglucomutase 1	353	0.87
chr7_149411412_149411638	0.17	KRBA1	KRAB-A domain containing 1	347	0.9
chr6_52463129_52463280	0.16	TRAM2	translocation associated membrane protein 2	21491	0.21
chr9_96793340_96793664	0.16	PTPDC1	protein tyrosine phosphatase domain containing 1	426	0.88
chr7_12443468_12443619	0.15	VWDE	von Willebrand factor D and EGF domains	12	0.99
chr20_3088467_3088718	0.15	UBOX5-AS1	UBOX5 antisense RNA 1	1033	0.39
chr4_8430147_8430298	0.14	ACOX3	acyl-CoA oxidase 3, pristanoyl	9	0.98
chr12_54350090_54350429	0.14	HOXC12	homeobox C12	1641	0.16
chr19_8008904_8009202	0.14	TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	248	0.81
chr12_133022629_133022780	0.14	MUC8	mucin 8	28022	0.17
chr2_240386919_240387070	0.14	AC062017.1	Uncharacterized protein	63495	0.11
chr9_99800693_99800974	0.13	CTSV	cathepsin V	759	0.71
chr18_74773774_74774062	0.13	MBP	myelin basic protein	43299	0.18
chr1_109643083_109643234	0.13	ENSG00000270066	.	343	0.8
chr6_109775900_109776051	0.13	MICAL1	microtubule associated monooxygenase, calponin and LIM domain containing 1	950	0.41
chr12_52569726_52569877	0.12	KRT80	keratin 80	15983	0.12
chr15_45353267_45353418	0.12	RP11-109D20.1		2437	0.16
chr10_103577270_103577421	0.12	MGEA5	meningioma expressed antigen 5 (hyaluronidase)	278	0.85
chr16_30007199_30007350	0.12	INO80E	INO80 complex subunit E	238	0.53
chr5_70751007_70751459	0.12	BDP1	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	209	0.96
chr1_19970427_19970607	0.12	NBL1	neuroblastoma 1, DAN family BMP antagonist	140	0.95
chr17_78796891_78797091	0.11	RP11-28G8.1		17559	0.21
chr10_121411607_121411991	0.11	BAG3	BCL2-associated athanogene 3	917	0.64
chr4_6326348_6326522	0.11	WFS1	Wolfram syndrome 1 (wolframin)	35633	0.19
chr11_9595375_9595526	0.11	WEE1	WEE1 G2 checkpoint kinase	222	0.91
chr10_130008845_130008996	0.10	MKI67	marker of proliferation Ki-67	84271	0.11
chr19_8454744_8454908	0.10	RAB11B	RAB11B, member RAS oncogene family	39	0.64
chr22_24321820_24321971	0.10	DDT	D-dopachrome tautomerase	124	0.8
chr4_8862024_8862175	0.10	RP13-582L3.4		454	0.85
chr1_3075630_3075886	0.10	RP1-163G9.2		25485	0.21
chr1_205426191_205426365	0.10	LEMD1	LEM domain containing 1	7219	0.17
chr9_34589972_34590123	0.10	CNTFR	ciliary neurotrophic factor receptor	74	0.94
chr2_121199656_121199846	0.09	LINC01101	long intergenic non-protein coding RNA 1101	23946	0.24
chr5_6633870_6634021	0.09	SRD5A1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	364	0.63
chr3_156544046_156544197	0.09	LEKR1	leucine, glutamate and lysine rich 1	18	0.99
chr3_15160267_15160418	0.09	ENSG00000221424	.	15695	0.16
chr11_63767165_63767355	0.09	OTUB1	OTU domain, ubiquitin aldehyde binding 1	12946	0.11
chr5_176734587_176734738	0.09	PRELID1	PRELI domain containing 1	2973	0.14
chr1_246230838_246231074	0.09	RP11-83A16.1		34103	0.18
chr2_45397824_45397975	0.09	SIX2	SIX homeobox 2	161330	0.04
chr13_113764056_113764207	0.09	F7	coagulation factor VII (serum prothrombin conversion accelerator)	4010	0.14
chr3_66023505_66023773	0.09	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	344	0.9
chr10_52382609_52382760	0.09	SGMS1	sphingomyelin synthase 1	1059	0.45
chr16_3207501_3207863	0.08	CASP16	caspase 16, apoptosis-related cysteine peptidase (putative)	13438	0.08
chr12_104682747_104683040	0.08	TXNRD1	thioredoxin reductase 1	220	0.93
chr1_1135456_1135661	0.08	TNFRSF18	tumor necrosis factor receptor superfamily, member 18	5502	0.08
chr16_75551132_75551283	0.08	RP11-77K12.5		12026	0.1
chr9_139426377_139426528	0.08	RP11-413M3.4		10881	0.09
chr1_6661858_6662009	0.08	KLHL21	kelch-like family member 21	996	0.41
chr13_103451004_103451240	0.08	KDELC1	KDEL (Lys-Asp-Glu-Leu) containing 1	235	0.52
chr20_58004406_58004557	0.08	ENSG00000263903	.	82946	0.1
chr1_198127223_198127697	0.08	NEK7	NIMA-related kinase 7	1209	0.65
chr16_2255933_2256271	0.08	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)	257	0.7
chr22_50765742_50765893	0.08	DENND6B	DENN/MADD domain containing 6B	328	0.78
chr4_8859377_8859610	0.08	RP13-582L3.4		3060	0.29
chr11_112832512_112832665	0.08	NCAM1	neural cell adhesion molecule 1	386	0.61
chr2_91997601_91997765	0.07	IGKV1OR-1	immunoglobulin kappa variable 1/OR-1 (pseudogene)	8114	0.25
chr1_27895325_27895557	0.07	AHDC1	AT hook, DNA binding motif, containing 1	34661	0.12
chr3_69591941_69592092	0.07	FRMD4B	FERM domain containing 4B	282	0.95
chr3_67704618_67704769	0.07	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	338	0.94
chr21_32930330_32930496	0.07	TIAM1	T-cell lymphoma invasion and metastasis 1	877	0.48
chr19_56592075_56592344	0.07	ZNF787	zinc finger protein 787	22644	0.12
chr2_60962980_60963131	0.07	ENSG00000252718	.	16280	0.19
chr3_183735605_183735756	0.07	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	3	0.96
chr17_17626155_17626306	0.07	RAI1	retinoic acid induced 1	40421	0.11
chr6_97285605_97285766	0.07	GPR63	G protein-coupled receptor 63	332	0.91
chr2_152494016_152494167	0.07	NEB	nebulin	53958	0.17
chr1_46954889_46955040	0.07	DMBX1	diencephalon/mesencephalon homeobox 1	17704	0.16
chr12_26111020_26111411	0.07	RASSF8-AS1	RASSF8 atnisense RNA 1	236	0.84
chr5_134375155_134375381	0.06	PITX1	paired-like homeodomain 1	4765	0.22
chr17_7464631_7464910	0.06	SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	502	0.46
chr17_80709161_80709321	0.06	TBCD	tubulin folding cofactor D	699	0.52
chr13_110437392_110437543	0.06	IRS2	insulin receptor substrate 2	1448	0.54
chr16_11295567_11296301	0.06	RMI2	RecQ mediated genome instability 2	47572	0.08
chr10_50604077_50604326	0.06	DRGX	dorsal root ganglia homeobox	704	0.7
chr17_5000284_5000552	0.06	ENSG00000234327	.	14345	0.09
chr7_117854342_117854690	0.06	ANKRD7	ankyrin repeat domain 7	10196	0.26
chr17_46675290_46675535	0.06	HOXB-AS3	HOXB cluster antisense RNA 3	1611	0.15
chr14_67708458_67708609	0.06	MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	189	0.95
chr14_100906069_100906661	0.05	RP11-362L22.1		33123	0.1
chr17_43096938_43097182	0.05	DCAKD	dephospho-CoA kinase domain containing	15449	0.12
chr4_76861765_76862107	0.05	NAAA	N-acylethanolamine acid amidase	190	0.92
chr6_43394965_43395176	0.05	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	34	0.96
chr21_28339316_28339602	0.05	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	627	0.77
chr22_20790969_20791236	0.05	SCARF2	scavenger receptor class F, member 2	1010	0.39
chr21_39755799_39755950	0.05	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	87026	0.09
chr17_79374508_79374888	0.05	ENSG00000266392	.	120	0.91
chr17_40215803_40215954	0.05	ZNF385C	zinc finger protein 385C	803	0.47
chr5_176918444_176918625	0.05	RP11-1334A24.6		3462	0.12
chr10_112404047_112404198	0.05	RBM20	RNA binding motif protein 20	33	0.96
chr10_94449168_94449319	0.05	HHEX	hematopoietically expressed homeobox	1298	0.46
chr1_233463868_233464019	0.05	MLK4	Mitogen-activated protein kinase kinase kinase MLK4	429	0.88
chr15_44093066_44093217	0.05	HYPK	huntingtin interacting protein K	344	0.48
chr4_140477398_140477823	0.05	SETD7	SET domain containing (lysine methyltransferase) 7	218	0.64
chr1_166890270_166890421	0.05	TADA1	transcriptional adaptor 1	44781	0.12
chr20_388183_388334	0.05	RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	116	0.95
chr9_136024815_136024979	0.05	RALGDS	ral guanine nucleotide dissociation stimulator	176	0.93
chr2_61696354_61697036	0.05	USP34	ubiquitin specific peptidase 34	1209	0.39
chr1_230561180_230561454	0.05	PGBD5	piggyBac transposable element derived 5	158	0.97
chr1_11750833_11751136	0.05	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	550	0.51
chr13_26625030_26625181	0.05	SHISA2	shisa family member 2	64	0.98
chr11_85565948_85566099	0.05	AP000974.1	CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein	37	0.6
chr19_49925689_49925950	0.05	PTH2	parathyroid hormone 2	879	0.27
chr11_63766456_63766677	0.05	OTUB1	OTU domain, ubiquitin aldehyde binding 1	12252	0.11
chr14_21100640_21100876	0.05	OR6S1	olfactory receptor, family 6, subfamily S, member 1	9092	0.1
chr11_61355500_61355795	0.05	SYT7	synaptotagmin VII	7027	0.19
chr21_36261605_36261866	0.05	RUNX1	runt-related transcription factor 1	299	0.95
chr1_47973634_47973787	0.05	ENSG00000221346	.	5534	0.24
chr20_7999916_8000067	0.04	RP5-971N18.3		121	0.84
chr10_35931971_35932320	0.04	FZD8	frizzled family receptor 8	1783	0.3
chr9_140008930_140009195	0.04	DPP7	dipeptidyl-peptidase 7	94	0.9
chr20_24961168_24961319	0.04	ENSG00000207355	.	6436	0.19
chr15_81426559_81426733	0.04	C15orf26	chromosome 15 open reading frame 26	58	0.98
chr2_28615239_28615407	0.04	FOSL2	FOS-like antigen 2	346	0.84
chr18_53447366_53447551	0.04	TCF4	transcription factor 4	115440	0.07
chr12_123716874_123717156	0.04	C12orf65	chromosome 12 open reading frame 65	448	0.55
chr5_76506800_76506951	0.04	PDE8B	phosphodiesterase 8B	124	0.97
chr7_151441431_151441582	0.04	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	8106	0.24
chr9_79637084_79637292	0.04	FOXB2	forkhead box B2	2617	0.4
chr6_116792861_116793073	0.04	RP1-93H18.6		8112	0.12
chr6_31632946_31633178	0.04	CSNK2B	casein kinase 2, beta polypeptide	49	0.51
chr1_205257351_205257502	0.04	TMCC2	transmembrane and coiled-coil domain family 2	32097	0.12
chr3_123167522_123167831	0.04	ADCY5	adenylate cyclase 5	929	0.67
chr5_43042322_43042506	0.04	AC025171.1		555	0.55
chr10_12392184_12392335	0.04	CAMK1D	calcium/calmodulin-dependent protein kinase ID	527	0.78
chr2_106350382_106350589	0.04	NCK2	NCK adaptor protein 2	10869	0.3
chr17_66130072_66130259	0.04	LRRC37A16P	leucine rich repeat containing 37, member A16, pseudogene	18444	0.18
chr2_231692888_231693039	0.04	ITM2C	integral membrane protein 2C	36391	0.14
chr10_99051887_99052112	0.04	ARHGAP19-SLIT1	ARHGAP19-SLIT1 readthrough (NMD candidate)	385	0.46
chr17_73511759_73511998	0.04	CASKIN2	CASK interacting protein 2	214	0.53
chr19_41025424_41025575	0.04	SPTBN4	spectrin, beta, non-erythrocytic 4	4952	0.16
chr6_33667031_33667259	0.04	ENSG00000266509	.	1240	0.36
chr5_139554573_139554724	0.04	CYSTM1	cysteine-rich transmembrane module containing 1	421	0.79
chr7_2559962_2560132	0.04	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	551	0.71
chr5_172755065_172755216	0.04	STC2	stanniocalcin 2	84	0.97
chr1_206235900_206236051	0.04	AVPR1B	arginine vasopressin receptor 1B	11999	0.16
chr1_57044924_57045096	0.04	PPAP2B	phosphatidic acid phosphatase type 2B	231	0.96
chr1_54205166_54205365	0.04	GLIS1	GLIS family zinc finger 1	5388	0.21
chrX_119149661_119149824	0.03	RP4-755D9.1		20459	0.16
chr19_13155541_13155731	0.03	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	19825	0.09
chr15_65823090_65823261	0.03	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	83	0.96
chr1_227923333_227923484	0.03	SNAP47	synaptosomal-associated protein, 47kDa	271	0.51
chr2_242843726_242843877	0.03	AC131097.4	Protein LOC285095	901	0.5
chr10_29699092_29699537	0.03	PTCHD3P1	patched domain containing 3 pseudogene 1	142	0.97
chr17_48637509_48637817	0.03	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	766	0.34
chr4_40464101_40464252	0.03	ENSG00000221122	.	1557	0.37
chr12_124017770_124017921	0.03	RILPL1	Rab interacting lysosomal protein-like 1	420	0.78
chr19_51339015_51339203	0.03	KLK15	kallikrein-related peptidase 15	1360	0.2
chr16_69166636_69166787	0.03	CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)	65	0.71
chr12_125011632_125011783	0.03	NCOR2	nuclear receptor corepressor 2	8442	0.31
chr14_100149110_100149261	0.03	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1	1466	0.43
chr17_71470730_71470881	0.03	RP11-449L23.2		39019	0.15
chr2_28616465_28616616	0.03	FOSL2	FOS-like antigen 2	815	0.43
chr14_65346129_65346280	0.03	SPTB	spectrin, beta, erythrocytic	351	0.83
chr11_64878785_64879153	0.03	AP003068.9		198	0.59
chr1_763102_763253	0.03	RP11-206L10.8		17636	0.13
chr18_52989024_52989286	0.03	TCF4	transcription factor 4	62	0.99
chr10_88471165_88471428	0.03	ENSG00000252189	.	34410	0.12
chr12_861875_862026	0.03	WNK1	WNK lysine deficient protein kinase 1	139	0.97
chr17_40169963_40170444	0.03	DNAJC7	DnaJ (Hsp40) homolog, subfamily C, member 7	333	0.74
chr22_47017266_47017440	0.03	GRAMD4	GRAM domain containing 4	1054	0.61
chr7_22618226_22618377	0.03	AC002480.4		11023	0.19
chr1_36929262_36929523	0.03	MRPS15	mitochondrial ribosomal protein S15	646	0.64
chr17_72856651_72856802	0.03	GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	68	0.95
chr14_21769078_21769230	0.03	RPGRIP1	retinitis pigmentosa GTPase regulator interacting protein 1	13018	0.15
chr2_132431451_132431687	0.03	C2orf27A	chromosome 2 open reading frame 27A	48379	0.15
chr6_160390514_160390665	0.03	IGF2R	insulin-like growth factor 2 receptor	458	0.84
chr13_25592288_25592454	0.03	LSP1	Lymphocyte-specific protein 1; Uncharacterized protein	830	0.67
chr8_146127349_146127646	0.03	ZNF250	zinc finger protein 250	56	0.97
chr11_119075992_119076532	0.03	CBL	Cbl proto-oncogene, E3 ubiquitin protein ligase	490	0.66
chr14_95155916_95156067	0.03	SERPINA13P	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene	48336	0.13
chr15_33602917_33603068	0.03	RP11-489D6.2		132	0.56
chr10_43724787_43724957	0.03	RASGEF1A	RasGEF domain family, member 1A	315	0.93
chr14_105554105_105554256	0.03	GPR132	G protein-coupled receptor 132	22398	0.17
chr7_149558765_149558916	0.03	RP4-751H13.7		741	0.62
chr17_1532878_1533035	0.03	SLC43A2	solute carrier family 43 (amino acid system L transporter), member 2	826	0.44
chr10_35104929_35105172	0.02	PARD3-AS1	PARD3 antisense RNA 1	355	0.75
chr1_33646715_33647017	0.02	TRIM62	tripartite motif containing 62	401	0.87
chr2_26407379_26407559	0.02	GAREML	GRB2 associated, regulator of MAPK1-like	3884	0.23
chr3_195636785_195636941	0.02	TNK2	tyrosine kinase, non-receptor, 2	908	0.4
chr1_202831073_202831286	0.02	RP11-480I12.5		2952	0.17
chr2_232479374_232479686	0.02	C2orf57	chromosome 2 open reading frame 57	21955	0.15
chr9_44751903_44752054	0.02	ENSG00000238933	.	98243	0.08
chr9_97021725_97021876	0.02	ZNF169	zinc finger protein 169	190	0.94
chr10_93393043_93393253	0.02	PPP1R3C	protein phosphatase 1, regulatory subunit 3C	337	0.93
chr11_120381906_120382148	0.02	GRIK4	glutamate receptor, ionotropic, kainate 4	441	0.5
chr4_74904557_74905248	0.02	CXCL3	chemokine (C-X-C motif) ligand 3	496	0.73
chr2_27071054_27071205	0.02	DPYSL5	dihydropyrimidinase-like 5	28	0.98
chr19_47951061_47951212	0.02	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	23984	0.12
chr4_6909496_6909954	0.02	TBC1D14	TBC1 domain family, member 14	1244	0.47
chr2_21022702_21022940	0.02	C2orf43	chromosome 2 open reading frame 43	9	0.99

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.2	GO:0042640	anagen(GO:0042640)
0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)

Results for CREB1

Z-value: 0.64

Motif logo

Transcription factors associated with CREB1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the CREB1 motif across conditions

Conditions sorted by the z-value of the CREB1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: