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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for CREB3L1_CREB3

Z-value: 0.86

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
CREB3L1
ENSG00000157613.6 cAMP responsive element binding protein 3 like 1
CREB3
ENSG00000107175.6 cAMP responsive element binding protein 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_35726344_35726495CREB359130.080709-0.599.8e-02Click!
chr9_35728507_35728765CREB336960.0928590.383.1e-01Click!
chr9_35731093_35731244CREB311640.2141570.333.8e-01Click!
chr9_35729585_35729939CREB325700.1120310.314.1e-01Click!
chr9_35729999_35730165CREB322500.1224890.314.1e-01Click!
chr11_46300717_46300868CREB3L115640.362796-0.674.8e-02Click!
chr11_46315736_46316001CREB3L18090.605315-0.646.3e-02Click!
chr11_46299587_46299738CREB3L14340.8142650.646.4e-02Click!
chr11_46312622_46312792CREB3L139700.206036-0.636.7e-02Click!
chr11_46306701_46306852CREB3L175480.178415-0.581.0e-01Click!

Activity of the CREB3L1_CREB3 motif across conditions

Conditions sorted by the z-value of the CREB3L1_CREB3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_179494304_179494455 0.42 RNF130
 ring finger protein 130
 4342
 0.24
chr21_39776237_39776431 0.39 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 94011
 0.08
chr2_60772484_60772807 0.38 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 7895
 0.25
chr12_110527109_110527260 0.37 C12orf76
 chromosome 12 open reading frame 76
 15693
 0.19
chr8_133845145_133845296 0.36 CTC-137K3.1
6796
 0.18
chr10_115821373_115821605 0.36 ADRB1
 adrenoceptor beta 1
 17683
 0.2
chr10_116259271_116259568 0.35 ABLIM1
 actin binding LIM protein 1
 11667
 0.26
chr3_121804577_121804728 0.35 CD86
 CD86 molecule
 5796
 0.23
chr12_62996382_62996533 0.34 RP11-631N16.2
75
 0.9
chr2_96812616_96812778 0.33 DUSP2
 dual specificity phosphatase 2
 1518
 0.33
chr20_5654993_5655144 0.32 GPCPD1
 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
 63396
 0.12
chr12_123380878_123381108 0.31 VPS37B
 vacuolar protein sorting 37 homolog B (S. cerevisiae)
 2
 0.97
chr6_25171772_25171923 0.31 ENSG00000222373
 .
 20794
 0.18
chr1_59964356_59964507 0.31 FGGY
 FGGY carbohydrate kinase domain containing
 55159
 0.17
chr12_114296240_114296499 0.30 RP11-780K2.1
74005
 0.12
chr2_223574012_223574225 0.30 ENSG00000238852
 .
 11399
 0.21
chr6_13294835_13295015 0.29 RP1-257A7.4
893
 0.6
chr6_130009100_130009346 0.29 ARHGAP18
 Rho GTPase activating protein 18
 22147
 0.24
chr1_160693296_160693447 0.29 CD48
 CD48 molecule
 11730
 0.15
chr8_35729581_35729732 0.28 AC012215.1
 Uncharacterized protein
 80291
 0.12
chr15_98703362_98703675 0.28 ENSG00000222361
 .
 85526
 0.1
chr9_137232344_137232495 0.28 RXRA
 retinoid X receptor, alpha
 13993
 0.23
chr6_15090109_15090260 0.28 ENSG00000242989
 .
 23015
 0.23
chr6_135514882_135515033 0.27 MYB-AS1
 MYB antisense RNA 1
 2176
 0.29
chr20_24823319_24823470 0.27 CST7
 cystatin F (leukocystatin)
 106472
 0.07
chr17_65850368_65850519 0.27 ENSG00000265086
 .
 10382
 0.18
chr17_81041562_81041843 0.26 METRNL
 meteorin, glial cell differentiation regulator-like
 247
 0.94
chr3_113326372_113326723 0.26 ENSG00000265253
 .
 12824
 0.16
chr4_80997125_80997368 0.26 ANTXR2
 anthrax toxin receptor 2
 2620
 0.4
chr7_30188840_30189132 0.26 MTURN
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
 3473
 0.2
chr5_36714763_36714914 0.26 CTD-2353F22.1
10437
 0.29
chr5_14332103_14332393 0.26 TRIO
 trio Rho guanine nucleotide exchange factor
 41162
 0.22
chr2_73869270_73869546 0.25 NAT8
 N-acetyltransferase 8 (GCN5-related, putative)
 112
 0.97
chr4_144278620_144278790 0.25 ENSG00000265623
 .
 14092
 0.2
chr6_34255201_34255352 0.25 C6orf1
 chromosome 6 open reading frame 1
 38029
 0.15
chr21_43866253_43866404 0.25 ENSG00000252619
 .
 28626
 0.11
chr19_35939108_35939372 0.25 FFAR2
 free fatty acid receptor 2
 37
 0.96
chr11_85867980_85868160 0.25 ENSG00000200877
 .
 3801
 0.28
chr5_58858867_58859046 0.25 PDE4D
 phosphodiesterase 4D, cAMP-specific
 23263
 0.28
chrX_25021375_25021628 0.25 ARX
 aristaless related homeobox
 12564
 0.27
chr3_45152072_45152512 0.24 CDCP1
 CUB domain containing protein 1
 35622
 0.16
chr10_6542814_6542965 0.24 PRKCQ
 protein kinase C, theta
 79312
 0.11
chr13_111522529_111522823 0.24 LINC00346
 long intergenic non-protein coding RNA 346
 514
 0.8
chr2_112368287_112368472 0.24 ENSG00000266063
 .
 160332
 0.04
chr2_31331242_31331393 0.23 GALNT14
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
 21173
 0.22
chr11_73181263_73181443 0.23 RP11-809N8.4
65011
 0.09
chr5_178609290_178609441 0.23 ZNF354C
 zinc finger protein 354C
 121949
 0.05
chr22_30658397_30658793 0.23 OSM
 oncostatin M
 3212
 0.13
chr4_183751040_183751191 0.23 ENSG00000221186
 .
 3734
 0.29
chr19_54703476_54703677 0.23 AC012314.20
262
 0.74
chr6_6970564_6970715 0.23 ENSG00000240936
 .
 31509
 0.21
chr12_111612228_111612379 0.23 CUX2
 cut-like homeobox 2
 75053
 0.1
chr15_40536086_40536237 0.23 PAK6
 p21 protein (Cdc42/Rac)-activated kinase 6
 3315
 0.14
chr21_39550882_39551033 0.22 ENSG00000238581
 .
 8699
 0.21
chr11_1863672_1864036 0.22 TNNI2
 troponin I type 2 (skeletal, fast)
 2430
 0.15
chr17_79056601_79056878 0.22 BAIAP2
 BAI1-associated protein 2
 3522
 0.15
chr11_12138065_12138216 0.22 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 103
 0.98
chr9_71362228_71362379 0.22 PIP5K1B
 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
 5132
 0.26
chr4_38179209_38179752 0.22 ENSG00000221495
 .
 60754
 0.15
chr1_192804077_192804228 0.21 RGS2
 regulator of G-protein signaling 2, 24kDa
 25981
 0.21
chrX_14048836_14048989 0.21 GEMIN8
 gem (nuclear organelle) associated protein 8
 900
 0.68
chr18_77551404_77551663 0.21 KCNG2
 potassium voltage-gated channel, subfamily G, member 2
 72135
 0.1
chr16_85855178_85855329 0.21 COX4I1
 cytochrome c oxidase subunit IV isoform 1
 20445
 0.12
chr19_47989123_47989274 0.21 NAPA-AS1
 NAPA antisense RNA 1
 1633
 0.23
chr10_95196392_95196543 0.21 MYOF
 myoferlin
 45484
 0.14
chr17_1528321_1528534 0.21 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
 3208
 0.14
chr19_440573_440724 0.21 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 1618
 0.25
chr10_75625910_75626399 0.20 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
 5542
 0.13
chr10_121410924_121411075 0.20 BAG3
 BCL2-associated athanogene 3
 117
 0.97
chr1_53102699_53102972 0.20 FAM159A
 family with sequence similarity 159, member A
 3819
 0.21
chr8_143815811_143815982 0.20 CTD-2292P10.2
6788
 0.09
chr7_5573568_5573766 0.20 ACTB
 actin, beta
 3327
 0.16
chr1_15105044_15105255 0.20 KAZN
 kazrin, periplakin interacting protein
 145477
 0.05
chr12_701008_701257 0.20 RP5-1154L15.1
1333
 0.32
chr11_69080924_69081075 0.20 MYEOV
 myeloma overexpressed
 19374
 0.26
chr3_178389375_178389526 0.20 KCNMB2
 potassium large conductance calcium-activated channel, subfamily M, beta member 2
 112832
 0.07
chr2_85762478_85762791 0.20 ENSG00000266577
 .
 2885
 0.13
chr12_132280950_132281101 0.20 ENSG00000200516
 .
 4954
 0.19
chr8_116891196_116891435 0.19 TRPS1
 trichorhinophalangeal syndrome I
 69416
 0.14
chr4_122617356_122617626 0.19 ANXA5
 annexin A5
 626
 0.78
chr6_6772446_6772597 0.19 LY86-AS1
 LY86 antisense RNA 1
 149517
 0.04
chr17_78560658_78560826 0.19 RPTOR
 regulatory associated protein of MTOR, complex 1
 41474
 0.17
chr6_42353003_42353575 0.19 ENSG00000221252
 .
 26845
 0.19
chr5_126312490_126312641 0.19 MARCH3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
 53935
 0.15
chr22_46299735_46299886 0.19 WNT7B
 wingless-type MMTV integration site family, member 7B
 68785
 0.09
chr20_62493774_62493925 0.19 C20ORF135
632
 0.43
chr17_73860452_73860737 0.19 WBP2
 WW domain binding protein 2
 8006
 0.08
chr12_68915435_68915586 0.18 RAP1B
 RAP1B, member of RAS oncogene family
 89109
 0.08
chr1_28524180_28524503 0.18 AL353354.2
2729
 0.14
chr13_27999670_27999878 0.18 GTF3A
 general transcription factor IIIA
 1093
 0.47
chr1_220978316_220978467 0.18 MARC1
 mitochondrial amidoxime reducing component 1
 8294
 0.19
chr8_6415371_6415522 0.18 ANGPT2
 angiopoietin 2
 5119
 0.29
chr6_82472333_82472746 0.18 ENSG00000206886
 .
 1202
 0.5
chr19_52270463_52270746 0.18 FPR2
 formyl peptide receptor 2
 1027
 0.41
chr22_38538827_38538978 0.18 PLA2G6
 phospholipase A2, group VI (cytosolic, calcium-independent)
 319
 0.85
chr16_51375269_51375420 0.18 SALL1
 spalt-like transcription factor 1
 190158
 0.03
chr3_12945715_12945869 0.18 AC034198.7
53634
 0.1
chrX_130913306_130913457 0.18 ENSG00000200587
 .
 159603
 0.04
chr11_63952754_63952905 0.18 STIP1
 stress-induced-phosphoprotein 1
 85
 0.93
chr2_62533078_62533236 0.18 ENSG00000238809
 .
 41027
 0.15
chr1_116195861_116196153 0.18 VANGL1
 VANGL planar cell polarity protein 1
 1984
 0.36
chr7_129347521_129347672 0.18 ENSG00000212238
 .
 48510
 0.11
chr15_78311678_78311855 0.18 TBC1D2B
 TBC1 domain family, member 2B
 17740
 0.12
chr1_38156448_38156698 0.18 C1orf109
 chromosome 1 open reading frame 109
 381
 0.76
chr10_50398424_50398575 0.18 C10orf128
 chromosome 10 open reading frame 128
 2063
 0.33
chr16_72942017_72942168 0.18 ENSG00000221799
 .
 76664
 0.08
chr21_40362776_40362927 0.17 ENSG00000272015
 .
 96142
 0.08
chr2_112763039_112763349 0.17 MERTK
 c-mer proto-oncogene tyrosine kinase
 13796
 0.22
chr17_80833585_80833738 0.17 TBCD
 tubulin folding cofactor D
 8367
 0.18
chr9_101984883_101985113 0.17 SEC61B
 Sec61 beta subunit
 415
 0.66
chr2_47839910_47840061 0.17 AC138655.1
 CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
 40384
 0.14
chr20_7997297_7997448 0.17 RP5-971N18.3
2498
 0.3
chr20_61555156_61555835 0.17 DIDO1
 death inducer-obliterator 1
 2326
 0.23
chr11_119560847_119560998 0.17 ENSG00000199217
 .
 33901
 0.14
chr11_44938433_44938696 0.17 TSPAN18
 tetraspanin 18
 10606
 0.25
chr22_35933430_35933581 0.17 RASD2
 RASD family, member 2
 3410
 0.3
chr19_45612723_45613017 0.17 PPP1R37
 protein phosphatase 1, regulatory subunit 37
 16438
 0.08
chr1_1101221_1101488 0.17 ENSG00000207730
 .
 1130
 0.25
chr21_43953040_43953239 0.17 SLC37A1
 solute carrier family 37 (glucose-6-phosphate transporter), member 1
 18505
 0.13
chr12_121665055_121665206 0.17 P2RX4
 purinergic receptor P2X, ligand-gated ion channel, 4
 17162
 0.17
chrX_65191097_65191248 0.17 RP6-159A1.3
28421
 0.2
chr16_75145410_75145702 0.17 RP11-252E2.1
946
 0.49
chr10_49907092_49907243 0.16 WDFY4
 WDFY family member 4
 10584
 0.23
chr1_159906503_159906698 0.16 IGSF9
 immunoglobulin superfamily, member 9
 8786
 0.1
chr17_47590468_47590727 0.16 NGFR
 nerve growth factor receptor
 15844
 0.14
chr19_13215621_13215858 0.16 LYL1
 lymphoblastic leukemia derived sequence 1
 1764
 0.21
chr6_26181116_26181267 0.16 HIST1H2BE
 histone cluster 1, H2be
 2767
 0.09
chr19_45253255_45253406 0.16 BCL3
 B-cell CLL/lymphoma 3
 1248
 0.31
chr5_169855198_169855349 0.16 KCNMB1
 potassium large conductance calcium-activated channel, subfamily M, beta member 1
 38592
 0.14
chr16_19124977_19125163 0.16 ITPRIPL2
 inositol 1,4,5-trisphosphate receptor interacting protein-like 2
 184
 0.93
chr2_112251056_112251269 0.16 ENSG00000266139
 .
 172494
 0.03
chr7_1859118_1859366 0.16 AC110781.3
 Protein LOC100128374
 18980
 0.17
chr3_28389894_28390045 0.16 AZI2
 5-azacytidine induced 2
 1
 0.94
chr14_91252167_91252318 0.16 TTC7B
 tetratricopeptide repeat domain 7B
 339
 0.92
chr10_5567264_5567415 0.16 RP11-116G8.5
366
 0.46
chr7_47616572_47616723 0.16 TNS3
 tensin 3
 4582
 0.32
chr9_34170162_34170313 0.16 UBAP1
 ubiquitin associated protein 1
 8766
 0.15
chr19_57683108_57683259 0.16 DUXA
 double homeobox A
 4372
 0.15
chr2_89157495_89157741 0.16 IGKJ5
 immunoglobulin kappa joining 5
 2499
 0.12
chr17_47486265_47486624 0.16 RP11-1079K10.4
5001
 0.13
chr11_129695943_129696094 0.16 TMEM45B
 transmembrane protein 45B
 10304
 0.27
chr17_35658363_35658514 0.16 ACACA
 acetyl-CoA carboxylase alpha
 1746
 0.42
chr2_60595552_60595831 0.16 ENSG00000200807
 .
 16049
 0.22
chr22_23909098_23909249 0.16 AP000345.2
78
 0.97
chr4_37853152_37853303 0.16 PGM2
 phosphoglucomutase 2
 24884
 0.21
chr1_162319832_162320115 0.15 ENSG00000207729
 .
 7637
 0.11
chr12_7905511_7905662 0.15 CLEC4C
 C-type lectin domain family 4, member C
 1385
 0.3
chr15_68502161_68502336 0.15 CALML4
 calmodulin-like 4
 3831
 0.2
chr20_31256682_31256833 0.15 RP11-410N8.4
67318
 0.08
chr19_16552842_16553129 0.15 CTD-2013N17.4
1228
 0.36
chr1_27560545_27560765 0.15 RP11-40H20.4
188
 0.68
chr16_646360_646511 0.15 RAB40C
 RAB40C, member RAS oncogene family
 6103
 0.07
chr12_58128131_58128282 0.15 AGAP2
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
 2594
 0.1
chr11_121454430_121454581 0.15 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 6623
 0.32
chr11_11523784_11523935 0.15 RP11-483L5.1
67772
 0.12
chr16_87802997_87803148 0.15 KLHDC4
 kelch domain containing 4
 3490
 0.22
chr22_44464688_44464966 0.15 PARVB
 parvin, beta
 114
 0.98
chr2_43633250_43633401 0.15 ENSG00000252804
 .
 2121
 0.44
chr2_238634076_238634227 0.15 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 33169
 0.17
chr12_7031787_7032018 0.15 ENO2
 enolase 2 (gamma, neuronal)
 1158
 0.2
chr1_204332619_204332786 0.15 PLEKHA6
 pleckstrin homology domain containing, family A member 6
 3658
 0.22
chr5_123646330_123646481 0.15 RP11-436H11.2
418119
 0.01
chr11_60914868_60915019 0.15 VPS37C
 vacuolar protein sorting 37 homolog C (S. cerevisiae)
 13665
 0.16
chr12_122230072_122230277 0.14 RHOF
 ras homolog family member F (in filopodia)
 1092
 0.46
chr7_129007754_129007992 0.14 AHCYL2
 adenosylhomocysteinase-like 2
 91
 0.97
chr16_66606248_66606582 0.14 CMTM1
 CKLF-like MARVEL transmembrane domain containing 1
 5998
 0.1
chr5_58055121_58055272 0.14 RP11-479O16.1
25410
 0.24
chr12_107350540_107350837 0.14 C12orf23
 chromosome 12 open reading frame 23
 125
 0.94
chr15_67833013_67833278 0.14 MAP2K5
 mitogen-activated protein kinase kinase 5
 1902
 0.39
chr5_130868870_130869280 0.14 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 349
 0.93
chr18_29210689_29211071 0.14 ENSG00000252379
 .
 38461
 0.11
chr19_28964296_28964459 0.14 ENSG00000238514
 .
 457533
 0.01
chr19_6059787_6060020 0.14 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
 2609
 0.21
chr14_86528076_86528227 0.14 FLRT2
 fibronectin leucine rich transmembrane protein 2
 531579
 0.0
chr10_101310900_101311051 0.14 NKX2-3
 NK2 homeobox 3
 18285
 0.15
chr22_43581545_43581696 0.14 TTLL12
 tubulin tyrosine ligase-like family, member 12
 1519
 0.32
chr3_176888184_176888459 0.14 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 25890
 0.2
chr1_25307295_25307446 0.14 RUNX3
 runt-related transcription factor 3
 15869
 0.19
chr3_107837151_107837302 0.14 CD47
 CD47 molecule
 27354
 0.24
chr9_95523817_95524060 0.14 BICD2
 bicaudal D homolog 2 (Drosophila)
 3156
 0.26
chr19_11159757_11160063 0.14 SMARCA4
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
 9601
 0.14
chr12_11897037_11897481 0.14 ETV6
 ets variant 6
 8176
 0.3
chr21_35709927_35710173 0.14 KCNE2
 potassium voltage-gated channel, Isk-related family, member 2
 26273
 0.13
chr5_171059986_171060137 0.14 ENSG00000264303
 .
 137473
 0.04
chr2_73263307_73263458 0.14 SFXN5
 sideroflexin 5
 35420
 0.16
chr22_28037496_28037647 0.14 RP11-375H17.1
74897
 0.12
chr2_173850166_173850396 0.14 RAPGEF4
 Rap guanine nucleotide exchange factor (GEF) 4
 41073
 0.18
chr13_99566346_99566616 0.14 DOCK9
 dedicator of cytokinesis 9
 58243
 0.13
chr3_128711977_128712128 0.14 KIAA1257
 KIAA1257
 867
 0.53
chr15_32948468_32948619 0.14 SCG5
 secretogranin V (7B2 protein)
 12719
 0.14
chr2_3583541_3583693 0.14 RP13-512J5.1
 Uncharacterized protein
 11930
 0.12
chr11_4489038_4489189 0.14 OR52K2
 olfactory receptor, family 52, subfamily K, member 2
 18588
 0.13
chr10_119303115_119303318 0.14 EMX2
 empty spiracles homeobox 2
 707
 0.63
chr3_142720005_142720156 0.14 U2SURP
 U2 snRNP-associated SURP domain containing
 286
 0.91
chr20_30184012_30184163 0.14 ID1
 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
 8999
 0.11
chr19_52552377_52552528 0.14 ZNF432
 zinc finger protein 432
 379
 0.77
chr20_60719765_60720239 0.14 SS18L1
 synovial sarcoma translocation gene on chromosome 18-like 1
 1151
 0.34
chr15_89165477_89165628 0.14 AEN
 apoptosis enhancing nuclease
 951
 0.49
chr17_80308630_80308781 0.14 TEX19
 testis expressed 19
 8418
 0.1
chr1_20905252_20905403 0.14 CDA
 cytidine deaminase
 10114
 0.17

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0021894 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0007625 grooming behavior(GO:0007625)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0032356 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism