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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CREB3L1_CREB3

Z-value: 0.86

Motif logo

Transcription factors associated with CREB3L1_CREB3

Gene Symbol	Gene ID	Gene Info
CREB3L1 Ensembl NCBI GeneCards UniProt	ENSG00000157613.6	CREB3L1
CREB3 Ensembl NCBI GeneCards UniProt	ENSG00000107175.6	CREB3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
CREB3	chr9_35726344_35726495	5913	0.080709	-0.59	9.8e-02	Click!
CREB3	chr9_35728507_35728765	3696	0.092859	0.38	3.1e-01	Click!
CREB3	chr9_35731093_35731244	1164	0.214157	0.33	3.8e-01	Click!
CREB3	chr9_35729585_35729939	2570	0.112031	0.31	4.1e-01	Click!
CREB3	chr9_35729999_35730165	2250	0.122489	0.31	4.1e-01	Click!
CREB3L1	chr11_46300717_46300868	1564	0.362796	-0.67	4.8e-02	Click!
CREB3L1	chr11_46315736_46316001	809	0.605315	-0.64	6.3e-02	Click!
CREB3L1	chr11_46299587_46299738	434	0.814265	0.64	6.4e-02	Click!
CREB3L1	chr11_46312622_46312792	3970	0.206036	-0.63	6.7e-02	Click!
CREB3L1	chr11_46306701_46306852	7548	0.178415	-0.58	1.0e-01	Click!

Activity of the CREB3L1_CREB3 motif across conditions

Conditions sorted by the z-value of the CREB3L1_CREB3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_179494304_179494455	0.42	RNF130	ring finger protein 130	4342	0.24
chr21_39776237_39776431	0.39	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	94011	0.08
chr2_60772484_60772807	0.38	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	7895	0.25
chr12_110527109_110527260	0.37	C12orf76	chromosome 12 open reading frame 76	15693	0.19
chr8_133845145_133845296	0.36	CTC-137K3.1		6796	0.18
chr10_115821373_115821605	0.36	ADRB1	adrenoceptor beta 1	17683	0.2
chr10_116259271_116259568	0.35	ABLIM1	actin binding LIM protein 1	11667	0.26
chr3_121804577_121804728	0.35	CD86	CD86 molecule	5796	0.23
chr12_62996382_62996533	0.34	RP11-631N16.2		75	0.9
chr2_96812616_96812778	0.33	DUSP2	dual specificity phosphatase 2	1518	0.33
chr20_5654993_5655144	0.32	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	63396	0.12
chr12_123380878_123381108	0.31	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	2	0.97
chr6_25171772_25171923	0.31	ENSG00000222373	.	20794	0.18
chr1_59964356_59964507	0.31	FGGY	FGGY carbohydrate kinase domain containing	55159	0.17
chr12_114296240_114296499	0.30	RP11-780K2.1		74005	0.12
chr2_223574012_223574225	0.30	ENSG00000238852	.	11399	0.21
chr6_13294835_13295015	0.29	RP1-257A7.4		893	0.6
chr6_130009100_130009346	0.29	ARHGAP18	Rho GTPase activating protein 18	22147	0.24
chr1_160693296_160693447	0.29	CD48	CD48 molecule	11730	0.15
chr8_35729581_35729732	0.28	AC012215.1	Uncharacterized protein	80291	0.12
chr15_98703362_98703675	0.28	ENSG00000222361	.	85526	0.1
chr9_137232344_137232495	0.28	RXRA	retinoid X receptor, alpha	13993	0.23
chr6_15090109_15090260	0.28	ENSG00000242989	.	23015	0.23
chr6_135514882_135515033	0.27	MYB-AS1	MYB antisense RNA 1	2176	0.29
chr20_24823319_24823470	0.27	CST7	cystatin F (leukocystatin)	106472	0.07
chr17_65850368_65850519	0.27	ENSG00000265086	.	10382	0.18
chr17_81041562_81041843	0.26	METRNL	meteorin, glial cell differentiation regulator-like	247	0.94
chr3_113326372_113326723	0.26	ENSG00000265253	.	12824	0.16
chr4_80997125_80997368	0.26	ANTXR2	anthrax toxin receptor 2	2620	0.4
chr7_30188840_30189132	0.26	MTURN	maturin, neural progenitor differentiation regulator homolog (Xenopus)	3473	0.2
chr5_36714763_36714914	0.26	CTD-2353F22.1		10437	0.29
chr5_14332103_14332393	0.26	TRIO	trio Rho guanine nucleotide exchange factor	41162	0.22
chr2_73869270_73869546	0.25	NAT8	N-acetyltransferase 8 (GCN5-related, putative)	112	0.97
chr4_144278620_144278790	0.25	ENSG00000265623	.	14092	0.2
chr6_34255201_34255352	0.25	C6orf1	chromosome 6 open reading frame 1	38029	0.15
chr21_43866253_43866404	0.25	ENSG00000252619	.	28626	0.11
chr19_35939108_35939372	0.25	FFAR2	free fatty acid receptor 2	37	0.96
chr11_85867980_85868160	0.25	ENSG00000200877	.	3801	0.28
chr5_58858867_58859046	0.25	PDE4D	phosphodiesterase 4D, cAMP-specific	23263	0.28
chrX_25021375_25021628	0.25	ARX	aristaless related homeobox	12564	0.27
chr3_45152072_45152512	0.24	CDCP1	CUB domain containing protein 1	35622	0.16
chr10_6542814_6542965	0.24	PRKCQ	protein kinase C, theta	79312	0.11
chr13_111522529_111522823	0.24	LINC00346	long intergenic non-protein coding RNA 346	514	0.8
chr2_112368287_112368472	0.24	ENSG00000266063	.	160332	0.04
chr2_31331242_31331393	0.23	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)	21173	0.22
chr11_73181263_73181443	0.23	RP11-809N8.4		65011	0.09
chr5_178609290_178609441	0.23	ZNF354C	zinc finger protein 354C	121949	0.05
chr22_30658397_30658793	0.23	OSM	oncostatin M	3212	0.13
chr4_183751040_183751191	0.23	ENSG00000221186	.	3734	0.29
chr19_54703476_54703677	0.23	AC012314.20		262	0.74
chr6_6970564_6970715	0.23	ENSG00000240936	.	31509	0.21
chr12_111612228_111612379	0.23	CUX2	cut-like homeobox 2	75053	0.1
chr15_40536086_40536237	0.23	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	3315	0.14
chr21_39550882_39551033	0.22	ENSG00000238581	.	8699	0.21
chr11_1863672_1864036	0.22	TNNI2	troponin I type 2 (skeletal, fast)	2430	0.15
chr17_79056601_79056878	0.22	BAIAP2	BAI1-associated protein 2	3522	0.15
chr11_12138065_12138216	0.22	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	103	0.98
chr9_71362228_71362379	0.22	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	5132	0.26
chr4_38179209_38179752	0.22	ENSG00000221495	.	60754	0.15
chr1_192804077_192804228	0.21	RGS2	regulator of G-protein signaling 2, 24kDa	25981	0.21
chrX_14048836_14048989	0.21	GEMIN8	gem (nuclear organelle) associated protein 8	900	0.68
chr18_77551404_77551663	0.21	KCNG2	potassium voltage-gated channel, subfamily G, member 2	72135	0.1
chr16_85855178_85855329	0.21	COX4I1	cytochrome c oxidase subunit IV isoform 1	20445	0.12
chr19_47989123_47989274	0.21	NAPA-AS1	NAPA antisense RNA 1	1633	0.23
chr10_95196392_95196543	0.21	MYOF	myoferlin	45484	0.14
chr17_1528321_1528534	0.21	SLC43A2	solute carrier family 43 (amino acid system L transporter), member 2	3208	0.14
chr19_440573_440724	0.21	SHC2	SHC (Src homology 2 domain containing) transforming protein 2	1618	0.25
chr10_75625910_75626399	0.20	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	5542	0.13
chr10_121410924_121411075	0.20	BAG3	BCL2-associated athanogene 3	117	0.97
chr1_53102699_53102972	0.20	FAM159A	family with sequence similarity 159, member A	3819	0.21
chr8_143815811_143815982	0.20	CTD-2292P10.2		6788	0.09
chr7_5573568_5573766	0.20	ACTB	actin, beta	3327	0.16
chr1_15105044_15105255	0.20	KAZN	kazrin, periplakin interacting protein	145477	0.05
chr12_701008_701257	0.20	RP5-1154L15.1		1333	0.32
chr11_69080924_69081075	0.20	MYEOV	myeloma overexpressed	19374	0.26
chr3_178389375_178389526	0.20	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2	112832	0.07
chr2_85762478_85762791	0.20	ENSG00000266577	.	2885	0.13
chr12_132280950_132281101	0.20	ENSG00000200516	.	4954	0.19
chr8_116891196_116891435	0.19	TRPS1	trichorhinophalangeal syndrome I	69416	0.14
chr4_122617356_122617626	0.19	ANXA5	annexin A5	626	0.78
chr6_6772446_6772597	0.19	LY86-AS1	LY86 antisense RNA 1	149517	0.04
chr17_78560658_78560826	0.19	RPTOR	regulatory associated protein of MTOR, complex 1	41474	0.17
chr6_42353003_42353575	0.19	ENSG00000221252	.	26845	0.19
chr5_126312490_126312641	0.19	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	53935	0.15
chr22_46299735_46299886	0.19	WNT7B	wingless-type MMTV integration site family, member 7B	68785	0.09
chr20_62493774_62493925	0.19	C20ORF135		632	0.43
chr17_73860452_73860737	0.19	WBP2	WW domain binding protein 2	8006	0.08
chr12_68915435_68915586	0.18	RAP1B	RAP1B, member of RAS oncogene family	89109	0.08
chr1_28524180_28524503	0.18	AL353354.2		2729	0.14
chr13_27999670_27999878	0.18	GTF3A	general transcription factor IIIA	1093	0.47
chr1_220978316_220978467	0.18	MARC1	mitochondrial amidoxime reducing component 1	8294	0.19
chr8_6415371_6415522	0.18	ANGPT2	angiopoietin 2	5119	0.29
chr6_82472333_82472746	0.18	ENSG00000206886	.	1202	0.5
chr19_52270463_52270746	0.18	FPR2	formyl peptide receptor 2	1027	0.41
chr22_38538827_38538978	0.18	PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	319	0.85
chr16_51375269_51375420	0.18	SALL1	spalt-like transcription factor 1	190158	0.03
chr3_12945715_12945869	0.18	AC034198.7		53634	0.1
chrX_130913306_130913457	0.18	ENSG00000200587	.	159603	0.04
chr11_63952754_63952905	0.18	STIP1	stress-induced-phosphoprotein 1	85	0.93
chr2_62533078_62533236	0.18	ENSG00000238809	.	41027	0.15
chr1_116195861_116196153	0.18	VANGL1	VANGL planar cell polarity protein 1	1984	0.36
chr7_129347521_129347672	0.18	ENSG00000212238	.	48510	0.11
chr15_78311678_78311855	0.18	TBC1D2B	TBC1 domain family, member 2B	17740	0.12
chr1_38156448_38156698	0.18	C1orf109	chromosome 1 open reading frame 109	381	0.76
chr10_50398424_50398575	0.18	C10orf128	chromosome 10 open reading frame 128	2063	0.33
chr16_72942017_72942168	0.18	ENSG00000221799	.	76664	0.08
chr21_40362776_40362927	0.17	ENSG00000272015	.	96142	0.08
chr2_112763039_112763349	0.17	MERTK	c-mer proto-oncogene tyrosine kinase	13796	0.22
chr17_80833585_80833738	0.17	TBCD	tubulin folding cofactor D	8367	0.18
chr9_101984883_101985113	0.17	SEC61B	Sec61 beta subunit	415	0.66
chr2_47839910_47840061	0.17	AC138655.1	CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein	40384	0.14
chr20_7997297_7997448	0.17	RP5-971N18.3		2498	0.3
chr20_61555156_61555835	0.17	DIDO1	death inducer-obliterator 1	2326	0.23
chr11_119560847_119560998	0.17	ENSG00000199217	.	33901	0.14
chr11_44938433_44938696	0.17	TSPAN18	tetraspanin 18	10606	0.25
chr22_35933430_35933581	0.17	RASD2	RASD family, member 2	3410	0.3
chr19_45612723_45613017	0.17	PPP1R37	protein phosphatase 1, regulatory subunit 37	16438	0.08
chr1_1101221_1101488	0.17	ENSG00000207730	.	1130	0.25
chr21_43953040_43953239	0.17	SLC37A1	solute carrier family 37 (glucose-6-phosphate transporter), member 1	18505	0.13
chr12_121665055_121665206	0.17	P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	17162	0.17
chrX_65191097_65191248	0.17	RP6-159A1.3		28421	0.2
chr16_75145410_75145702	0.17	RP11-252E2.1		946	0.49
chr10_49907092_49907243	0.16	WDFY4	WDFY family member 4	10584	0.23
chr1_159906503_159906698	0.16	IGSF9	immunoglobulin superfamily, member 9	8786	0.1
chr17_47590468_47590727	0.16	NGFR	nerve growth factor receptor	15844	0.14
chr19_13215621_13215858	0.16	LYL1	lymphoblastic leukemia derived sequence 1	1764	0.21
chr6_26181116_26181267	0.16	HIST1H2BE	histone cluster 1, H2be	2767	0.09
chr19_45253255_45253406	0.16	BCL3	B-cell CLL/lymphoma 3	1248	0.31
chr5_169855198_169855349	0.16	KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	38592	0.14
chr16_19124977_19125163	0.16	ITPRIPL2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2	184	0.93
chr2_112251056_112251269	0.16	ENSG00000266139	.	172494	0.03
chr7_1859118_1859366	0.16	AC110781.3	Protein LOC100128374	18980	0.17
chr3_28389894_28390045	0.16	AZI2	5-azacytidine induced 2	1	0.94
chr14_91252167_91252318	0.16	TTC7B	tetratricopeptide repeat domain 7B	339	0.92
chr10_5567264_5567415	0.16	RP11-116G8.5		366	0.46
chr7_47616572_47616723	0.16	TNS3	tensin 3	4582	0.32
chr9_34170162_34170313	0.16	UBAP1	ubiquitin associated protein 1	8766	0.15
chr19_57683108_57683259	0.16	DUXA	double homeobox A	4372	0.15
chr2_89157495_89157741	0.16	IGKJ5	immunoglobulin kappa joining 5	2499	0.12
chr17_47486265_47486624	0.16	RP11-1079K10.4		5001	0.13
chr11_129695943_129696094	0.16	TMEM45B	transmembrane protein 45B	10304	0.27
chr17_35658363_35658514	0.16	ACACA	acetyl-CoA carboxylase alpha	1746	0.42
chr2_60595552_60595831	0.16	ENSG00000200807	.	16049	0.22
chr22_23909098_23909249	0.16	AP000345.2		78	0.97
chr4_37853152_37853303	0.16	PGM2	phosphoglucomutase 2	24884	0.21
chr1_162319832_162320115	0.15	ENSG00000207729	.	7637	0.11
chr12_7905511_7905662	0.15	CLEC4C	C-type lectin domain family 4, member C	1385	0.3
chr15_68502161_68502336	0.15	CALML4	calmodulin-like 4	3831	0.2
chr20_31256682_31256833	0.15	RP11-410N8.4		67318	0.08
chr19_16552842_16553129	0.15	CTD-2013N17.4		1228	0.36
chr1_27560545_27560765	0.15	RP11-40H20.4		188	0.68
chr16_646360_646511	0.15	RAB40C	RAB40C, member RAS oncogene family	6103	0.07
chr12_58128131_58128282	0.15	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	2594	0.1
chr11_121454430_121454581	0.15	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	6623	0.32
chr11_11523784_11523935	0.15	RP11-483L5.1		67772	0.12
chr16_87802997_87803148	0.15	KLHDC4	kelch domain containing 4	3490	0.22
chr22_44464688_44464966	0.15	PARVB	parvin, beta	114	0.98
chr2_43633250_43633401	0.15	ENSG00000252804	.	2121	0.44
chr2_238634076_238634227	0.15	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	33169	0.17
chr12_7031787_7032018	0.15	ENO2	enolase 2 (gamma, neuronal)	1158	0.2
chr1_204332619_204332786	0.15	PLEKHA6	pleckstrin homology domain containing, family A member 6	3658	0.22
chr5_123646330_123646481	0.15	RP11-436H11.2		418119	0.01
chr11_60914868_60915019	0.15	VPS37C	vacuolar protein sorting 37 homolog C (S. cerevisiae)	13665	0.16
chr12_122230072_122230277	0.14	RHOF	ras homolog family member F (in filopodia)	1092	0.46
chr7_129007754_129007992	0.14	AHCYL2	adenosylhomocysteinase-like 2	91	0.97
chr16_66606248_66606582	0.14	CMTM1	CKLF-like MARVEL transmembrane domain containing 1	5998	0.1
chr5_58055121_58055272	0.14	RP11-479O16.1		25410	0.24
chr12_107350540_107350837	0.14	C12orf23	chromosome 12 open reading frame 23	125	0.94
chr15_67833013_67833278	0.14	MAP2K5	mitogen-activated protein kinase kinase 5	1902	0.39
chr5_130868870_130869280	0.14	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	349	0.93
chr18_29210689_29211071	0.14	ENSG00000252379	.	38461	0.11
chr19_28964296_28964459	0.14	ENSG00000238514	.	457533	0.01
chr19_6059787_6060020	0.14	RFX2	regulatory factor X, 2 (influences HLA class II expression)	2609	0.21
chr14_86528076_86528227	0.14	FLRT2	fibronectin leucine rich transmembrane protein 2	531579	0.0
chr10_101310900_101311051	0.14	NKX2-3	NK2 homeobox 3	18285	0.15
chr22_43581545_43581696	0.14	TTLL12	tubulin tyrosine ligase-like family, member 12	1519	0.32
chr3_176888184_176888459	0.14	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	25890	0.2
chr1_25307295_25307446	0.14	RUNX3	runt-related transcription factor 3	15869	0.19
chr3_107837151_107837302	0.14	CD47	CD47 molecule	27354	0.24
chr9_95523817_95524060	0.14	BICD2	bicaudal D homolog 2 (Drosophila)	3156	0.26
chr19_11159757_11160063	0.14	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	9601	0.14
chr12_11897037_11897481	0.14	ETV6	ets variant 6	8176	0.3
chr21_35709927_35710173	0.14	KCNE2	potassium voltage-gated channel, Isk-related family, member 2	26273	0.13
chr5_171059986_171060137	0.14	ENSG00000264303	.	137473	0.04
chr2_73263307_73263458	0.14	SFXN5	sideroflexin 5	35420	0.16
chr22_28037496_28037647	0.14	RP11-375H17.1		74897	0.12
chr2_173850166_173850396	0.14	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4	41073	0.18
chr13_99566346_99566616	0.14	DOCK9	dedicator of cytokinesis 9	58243	0.13
chr3_128711977_128712128	0.14	KIAA1257	KIAA1257	867	0.53
chr15_32948468_32948619	0.14	SCG5	secretogranin V (7B2 protein)	12719	0.14
chr2_3583541_3583693	0.14	RP13-512J5.1	Uncharacterized protein	11930	0.12
chr11_4489038_4489189	0.14	OR52K2	olfactory receptor, family 52, subfamily K, member 2	18588	0.13
chr10_119303115_119303318	0.14	EMX2	empty spiracles homeobox 2	707	0.63
chr3_142720005_142720156	0.14	U2SURP	U2 snRNP-associated SURP domain containing	286	0.91
chr20_30184012_30184163	0.14	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	8999	0.11
chr19_52552377_52552528	0.14	ZNF432	zinc finger protein 432	379	0.77
chr20_60719765_60720239	0.14	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1	1151	0.34
chr15_89165477_89165628	0.14	AEN	apoptosis enhancing nuclease	951	0.49
chr17_80308630_80308781	0.14	TEX19	testis expressed 19	8418	0.1
chr1_20905252_20905403	0.14	CDA	cytidine deaminase	10114	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0007625	grooming behavior(GO:0007625)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.3	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	GO:0042629	mast cell granule(GO:0042629)
0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	GO:0032444	activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	GO:0043398	HLH domain binding(GO:0043398)
0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	GO:0032356	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	GO:0031014	troponin T binding(GO:0031014)
0.3	GO:0005048	signal sequence binding(GO:0005048)
0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism