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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for CREB5_CREM_JUNB

Z-value: 0.95

Motif logo

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 cAMP responsive element binding protein 5
CREM
ENSG00000095794.15 cAMP responsive element modulator
JUNB
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_28725973_28726124CREB54500.9056930.854.0e-03Click!
chr7_28647428_28647579CREB511750.6612540.809.3e-03Click!
chr7_28893632_28893840CREB5447100.1828830.791.1e-02Click!
chr7_28893326_28893622CREB5444480.1837450.781.3e-02Click!
chr7_28450467_28450674CREB515640.5589900.771.5e-02Click!
chr10_35417017_35417356CREM7810.4691780.618.4e-02Click!
chr10_35418232_35418383CREM19020.239169-0.511.6e-01Click!
chr10_35454351_35454502CREM20180.269871-0.481.9e-01Click!
chr10_35438600_35438751CREM13750.3615200.422.6e-01Click!
chr10_35484071_35484414CREM1670.9380500.383.2e-01Click!
chr19_12904796_12904947JUNB25610.0949190.836.0e-03Click!
chr19_12901212_12902001JUNB7040.3807160.791.2e-02Click!
chr19_12903336_12903487JUNB11010.2278870.713.4e-02Click!
chr19_12903631_12903782JUNB13960.1723470.627.8e-02Click!
chr19_12902017_12902168JUNB2180.8058740.551.3e-01Click!

Activity of the CREB5_CREM_JUNB motif across conditions

Conditions sorted by the z-value of the CREB5_CREM_JUNB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_133022629_133022780 1.21 MUC8
 mucin 8
 28022
 0.17
chr1_11901364_11901515 0.65 NPPA-AS1
 NPPA antisense RNA 1
 365
 0.78
chr7_100782348_100782499 0.43 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 12044
 0.1
chr10_6959147_6959298 0.43 PRKCQ
 protein kinase C, theta
 336959
 0.01
chr4_153913148_153913299 0.42 FHDC1
 FH2 domain containing 1
 49088
 0.16
chr3_134092582_134092733 0.41 AMOTL2
 angiomotin like 2
 18
 0.98
chr11_12695755_12695947 0.39 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 118
 0.98
chr1_111033550_111033701 0.38 KCNA10
 potassium voltage-gated channel, shaker-related subfamily, member 10
 28172
 0.13
chr13_45343452_45343641 0.38 ENSG00000238932
 .
 140737
 0.04
chr17_55446479_55446630 0.38 ENSG00000263902
 .
 43008
 0.17
chr18_20840672_20840823 0.37 RP11-17J14.2
429
 0.89
chr15_94850174_94850340 0.37 MCTP2
 multiple C2 domains, transmembrane 2
 8762
 0.33
chr8_49838453_49838744 0.35 SNAI2
 snail family zinc finger 2
 4299
 0.35
chr12_102872919_102873119 0.35 IGF1
 insulin-like growth factor 1 (somatomedin C)
 590
 0.85
chr18_22820121_22820315 0.35 ZNF521
 zinc finger protein 521
 8724
 0.3
chr6_80714655_80715350 0.34 TTK
 TTK protein kinase
 451
 0.88
chr2_38762873_38763024 0.34 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 34030
 0.18
chr1_161274764_161274974 0.33 MPZ
 myelin protein zero
 2392
 0.18
chr9_137348457_137348644 0.33 RXRA
 retinoid X receptor, alpha
 50122
 0.15
chr12_89511566_89511717 0.32 ENSG00000238302
 .
 164421
 0.04
chr1_205216416_205216567 0.32 TMCC2
 transmembrane and coiled-coil domain family 2
 743
 0.63
chr19_35849271_35849508 0.29 FFAR3
 free fatty acid receptor 3
 27
 0.95
chr11_65256298_65256486 0.29 AP000769.1
 Uncharacterized protein
 33664
 0.08
chr5_88566884_88567035 0.28 MEF2C-AS1
 MEF2C antisense RNA 1
 147665
 0.05
chrY_2576678_2576907 0.28 ENSG00000251841
 .
 75998
 0.11
chr3_141514797_141515122 0.27 ENSG00000265391
 .
 8206
 0.2
chr2_11888981_11889322 0.27 LPIN1
 lipin 1
 2387
 0.21
chr11_59279292_59279443 0.27 OR4D9
 olfactory receptor, family 4, subfamily D, member 9
 3019
 0.16
chr13_97876107_97876342 0.27 MBNL2
 muscleblind-like splicing regulator 2
 1615
 0.53
chr1_66999113_66999318 0.27 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 60
 0.98
chr22_44569121_44569281 0.27 PARVG
 parvin, gamma
 365
 0.92
chr4_174198585_174198817 0.26 ENSG00000221296
 .
 9390
 0.17
chr2_29537156_29537327 0.26 ALK
 anaplastic lymphoma receptor tyrosine kinase
 90981
 0.08
chr22_30662165_30662316 0.25 OSM
 oncostatin M
 433
 0.7
chr16_75587106_75587257 0.25 TMEM231
 transmembrane protein 231
 2955
 0.16
chr4_159131101_159131306 0.24 TMEM144
 transmembrane protein 144
 143
 0.96
chrX_2626678_2626926 0.24 CD99
 CD99 molecule
 17261
 0.2
chr12_53784490_53784671 0.23 SP1
 Sp1 transcription factor
 9494
 0.12
chr5_170739623_170739799 0.22 TLX3
 T-cell leukemia homeobox 3
 3423
 0.23
chr7_5492772_5492923 0.22 TNRC18
 trinucleotide repeat containing 18
 27802
 0.1
chr2_144280347_144280652 0.22 AC096558.1
42141
 0.16
chr12_19389657_19389808 0.22 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 126
 0.97
chr1_2216519_2216670 0.22 RP4-713A8.1
41538
 0.09
chr7_138393128_138393279 0.22 SVOPL
 SVOP-like
 7106
 0.24
chr6_14477462_14477818 0.22 ENSG00000206960
 .
 169126
 0.04
chr9_123346254_123346525 0.21 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
 3952
 0.35
chr6_53213778_53213929 0.21 ELOVL5
 ELOVL fatty acid elongase 5
 48
 0.98
chr9_130912677_130912874 0.21 LCN2
 lipocalin 2
 978
 0.34
chr15_98224143_98224294 0.21 LINC00923
 long intergenic non-protein coding RNA 923
 193562
 0.03
chr15_49336349_49337349 0.21 SECISBP2L
 SECIS binding protein 2-like
 1781
 0.28
chr4_113298543_113298694 0.20 ALPK1
 alpha-kinase 1
 80082
 0.08
chr2_28114153_28114304 0.20 RBKS
 ribokinase
 263
 0.74
chr2_95745044_95745195 0.20 AC103563.9
26198
 0.14
chr4_186316955_186317190 0.20 LRP2BP
 LRP2 binding protein
 19
 0.61
chr17_75531537_75531688 0.19 SEPT9
 septin 9
 53617
 0.12
chr6_119417895_119418107 0.19 FAM184A
 family with sequence similarity 184, member A
 17657
 0.19
chr21_18983750_18984027 0.18 BTG3
 BTG family, member 3
 1274
 0.5
chr18_46557895_46558135 0.18 RP11-15F12.1
7942
 0.2
chr3_50337208_50337424 0.18 HYAL3
 hyaluronoglucosaminidase 3
 417
 0.42
chr1_231173648_231173799 0.18 FAM89A
 family with sequence similarity 89, member A
 2269
 0.26
chr17_27889238_27889394 0.18 RP11-68I3.2
1751
 0.18
chr2_8552253_8552511 0.18 AC011747.7
263514
 0.02
chr1_22380057_22380208 0.18 CDC42
 cell division cycle 42
 342
 0.82
chr12_62861008_62861159 0.17 MON2
 MON2 homolog (S. cerevisiae)
 454
 0.83
chr1_236229504_236229679 0.17 NID1
 nidogen 1
 1129
 0.52
chr2_160471369_160471526 0.17 AC009506.1
360
 0.68
chr16_57770832_57771049 0.17 KATNB1
 katanin p80 (WD repeat containing) subunit B 1
 55
 0.96
chr16_48428377_48428528 0.17 SIAH1
 siah E3 ubiquitin protein ligase 1
 586
 0.72
chr19_996464_996712 0.17 AC004528.1
 Uncharacterized protein
 3013
 0.1
chrY_6954060_6954211 0.17 TBL1Y
 transducin (beta)-like 1, Y-linked
 175408
 0.03
chr5_73730230_73730381 0.16 ENSG00000244326
 .
 116494
 0.06
chr12_54446931_54447133 0.16 HOXC4
 homeobox C4
 629
 0.5
chr12_108958034_108958185 0.16 ISCU
 iron-sulfur cluster assembly enzyme
 1723
 0.27
chr6_158508122_158508351 0.16 SYNJ2
 synaptojanin 2
 9524
 0.2
chr8_65490045_65490217 0.16 RP11-21C4.1
311
 0.91
chr4_8430147_8430298 0.16 ACOX3
 acyl-CoA oxidase 3, pristanoyl
 9
 0.98
chr18_10791557_10791762 0.16 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 11
 0.99
chr10_43474933_43475084 0.16 ENSG00000263795
 .
 18003
 0.25
chr9_86323490_86324000 0.16 RP11-522I20.3
512
 0.52
chr16_16047180_16047331 0.16 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 3821
 0.26
chr17_42423914_42424082 0.16 GRN
 granulin
 1325
 0.25
chr19_38908795_38908946 0.16 RASGRP4
 RAS guanyl releasing protein 4
 7932
 0.09
chr8_6114669_6114820 0.16 RP11-115C21.2
149319
 0.04
chr14_101292334_101292485 0.15 AL117190.2
3128
 0.07
chr18_74205447_74205647 0.15 ZNF516
 zinc finger protein 516
 1599
 0.27
chr21_44937001_44937451 0.15 SIK1
 salt-inducible kinase 1
 90218
 0.08
chr15_40636361_40636512 0.15 C15orf52
 chromosome 15 open reading frame 52
 3268
 0.1
chr2_218027426_218027577 0.15 ENSG00000251849
 .
 13720
 0.27
chr14_71246503_71246654 0.15 MAP3K9
 mitogen-activated protein kinase kinase kinase 9
 3579
 0.34
chr7_1979584_1979735 0.15 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 526
 0.85
chr2_102093131_102093315 0.15 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 2058
 0.43
chr6_90929386_90929701 0.15 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 76918
 0.1
chr9_134516940_134517091 0.15 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 15680
 0.22
chr2_11838198_11838349 0.15 AC106875.1
16686
 0.12
chr1_32810829_32811029 0.14 TSSK3
 testis-specific serine kinase 3
 8126
 0.12
chr20_33146664_33146909 0.14 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 264
 0.91
chr6_138126801_138126952 0.14 RP11-356I2.4
20155
 0.19
chr21_36206001_36206152 0.14 RUNX1
 runt-related transcription factor 1
 53404
 0.16
chr20_45934513_45934664 0.14 ENSG00000265532
 .
 2538
 0.2
chr17_65505786_65506259 0.14 CTD-2653B5.1
14575
 0.17
chr22_39163031_39163182 0.14 SUN2
 Sad1 and UNC84 domain containing 2
 11101
 0.08
chr6_2449367_2449525 0.14 ENSG00000266252
 .
 39577
 0.21
chr5_70751007_70751459 0.14 BDP1
 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
 209
 0.96
chr1_17630639_17630914 0.14 PADI4
 peptidyl arginine deiminase, type IV
 3914
 0.2
chr17_72783237_72783388 0.14 TMEM104
 transmembrane protein 104
 10653
 0.11
chr19_8454744_8454908 0.14 RAB11B
 RAB11B, member RAS oncogene family
 39
 0.64
chr1_28099274_28099549 0.13 STX12
 syntaxin 12
 283
 0.78
chr16_73072287_73072438 0.13 ZFHX3
 zinc finger homeobox 3
 9912
 0.21
chr5_66492437_66492594 0.13 CD180
 CD180 molecule
 112
 0.98
chr3_128195185_128195336 0.13 DNAJB8
 DnaJ (Hsp40) homolog, subfamily B, member 8
 9169
 0.15
chr16_22825426_22825577 0.13 HS3ST2
 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
 3
 0.99
chr2_65309092_65309434 0.13 RAB1A
 RAB1A, member RAS oncogene family
 24261
 0.15
chr2_70750633_70750894 0.13 TGFA
 transforming growth factor, alpha
 29859
 0.16
chr5_64331605_64331756 0.13 ENSG00000207439
 .
 87516
 0.1
chr20_62580456_62580607 0.13 UCKL1
 uridine-cytidine kinase 1-like 1
 1948
 0.13
chr8_125726263_125726555 0.13 MTSS1
 metastasis suppressor 1
 13448
 0.25
chr4_141015090_141015375 0.13 RP11-392B6.1
33937
 0.2
chr7_132095239_132095390 0.13 AC011625.1
58221
 0.15
chr21_36295704_36295877 0.13 RUNX1
 runt-related transcription factor 1
 33703
 0.24
chr1_206235900_206236051 0.13 AVPR1B
 arginine vasopressin receptor 1B
 11999
 0.16
chr1_15433135_15433286 0.12 TMEM51
 transmembrane protein 51
 45818
 0.16
chr2_171210862_171211026 0.12 AC012594.1
3316
 0.37
chr4_154713480_154713740 0.12 SFRP2
 secreted frizzled-related protein 2
 3338
 0.26
chr15_70821207_70821700 0.12 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 173167
 0.03
chr16_58535345_58535501 0.12 NDRG4
 NDRG family member 4
 16
 0.97
chr19_4584744_4584943 0.12 SEMA6B
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 25023
 0.09
chr9_114288073_114288445 0.12 ZNF483
 zinc finger protein 483
 746
 0.65
chr12_78813400_78813551 0.12 NAV3
 neuron navigator 3
 220619
 0.02
chr8_146012726_146012877 0.12 ZNF34
 zinc finger protein 34
 71
 0.94
chr21_43673739_43673890 0.12 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 2380
 0.26
chr19_44087068_44087219 0.12 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
 1954
 0.14
chr10_43429375_43429752 0.12 ENSG00000263795
 .
 63448
 0.12
chr7_142216694_142216845 0.12 MTRNR2L6
 MT-RNR2-like 6
 157335
 0.04
chr6_108486750_108487194 0.12 OSTM1
 osteopetrosis associated transmembrane protein 1
 72
 0.78
chr20_30192135_30192286 0.12 ID1
 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
 876
 0.44
chr9_78990142_78990293 0.12 RFK
 riboflavin kinase
 18831
 0.24
chr14_75801482_75801633 0.11 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 54661
 0.1
chr15_80365699_80365932 0.11 ZFAND6
 zinc finger, AN1-type domain 6
 883
 0.66
chr10_121580538_121580689 0.11 INPP5F
 inositol polyphosphate-5-phosphatase F
 2385
 0.32
chr1_151254019_151254394 0.11 ZNF687
 zinc finger protein 687
 112
 0.61
chr2_44345424_44345575 0.11 ENSG00000252599
 .
 36535
 0.15
chr13_113664073_113664237 0.11 RP11-120K24.5
170
 0.9
chr19_6552264_6552452 0.11 ENSG00000199223
 .
 20710
 0.1
chr2_110013073_110013224 0.11 ENSG00000265965
 .
 83067
 0.11
chrX_129318276_129318427 0.11 RAB33A
 RAB33A, member RAS oncogene family
 12728
 0.19
chr2_66723271_66723422 0.11 MEIS1
 Meis homeobox 1
 12713
 0.22
chr3_62304486_62304637 0.11 ENSG00000241472
 .
 6
 0.57
chr2_111453217_111453510 0.11 BUB1
 BUB1 mitotic checkpoint serine/threonine kinase
 17672
 0.21
chr2_1609070_1609221 0.11 AC144450.1
14740
 0.26
chr18_60859816_60859967 0.11 ENSG00000238988
 .
 2007
 0.39
chr2_197944933_197945147 0.11 ANKRD44
 ankyrin repeat domain 44
 30528
 0.22
chr10_71992203_71992435 0.11 PPA1
 pyrophosphatase (inorganic) 1
 841
 0.65
chr10_12379442_12379593 0.11 ENSG00000264036
 .
 9129
 0.18
chr9_137263810_137263961 0.11 ENSG00000263897
 .
 7372
 0.25
chr6_44355096_44355314 0.11 CDC5L
 cell division cycle 5-like
 57
 0.97
chr2_219434859_219435206 0.11 RQCD1
 RCD1 required for cell differentiation1 homolog (S. pombe)
 1434
 0.25
chr1_151809393_151809571 0.11 C2CD4D
 C2 calcium-dependent domain containing 4D
 3551
 0.1
chr2_62520408_62520559 0.11 ENSG00000238809
 .
 28353
 0.17
chr1_167193026_167193202 0.11 POU2F1
 POU class 2 homeobox 1
 2971
 0.23
chrX_83757427_83757578 0.11 HDX
 highly divergent homeobox
 15
 0.51
chr4_174443398_174443549 0.10 HAND2-AS1
 HAND2 antisense RNA 1 (head to head)
 4948
 0.23
chr14_102785720_102785871 0.10 ZNF839
 zinc finger protein 839
 160
 0.94
chr20_17207212_17207363 0.10 PCSK2
 proprotein convertase subtilisin/kexin type 2
 349
 0.9
chr2_47213208_47213406 0.10 RP11-15I20.1
29280
 0.14
chr1_172189218_172189369 0.10 DNM3OS
 DNM3 opposite strand/antisense RNA
 75359
 0.09
chr3_122513525_122513727 0.10 DIRC2
 disrupted in renal carcinoma 2
 16
 0.96
chr2_203735601_203735829 0.10 ICA1L
 islet cell autoantigen 1,69kDa-like
 54
 0.98
chr3_8543150_8543354 0.10 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 32
 0.64
chr19_49142340_49142538 0.10 CA11
 carbonic anhydrase XI
 277
 0.77
chr2_8144515_8144736 0.10 ENSG00000221255
 .
 427653
 0.01
chr2_28837076_28837338 0.10 PLB1
 phospholipase B1
 12421
 0.21
chr3_185080983_185081411 0.10 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
 289
 0.93
chr18_3712580_3712731 0.10 RP11-874J12.3
58775
 0.1
chr8_67343364_67343686 0.10 ADHFE1
 alcohol dehydrogenase, iron containing, 1
 1105
 0.48
chr3_115231996_115232281 0.10 GAP43
 growth associated protein 43
 110033
 0.07
chr8_38385040_38385321 0.10 C8orf86
 chromosome 8 open reading frame 86
 995
 0.59
chr14_81736950_81737101 0.10 STON2
 stonin 2
 6252
 0.26
chr10_1296680_1296831 0.10 ADARB2
 adenosine deaminase, RNA-specific, B2 (non-functional)
 50430
 0.16
chr7_138914973_138915166 0.10 UBN2
 ubinuclein 2
 33
 0.98
chr12_4229354_4229505 0.10 CCND2
 cyclin D2
 153509
 0.04
chr5_138738832_138739361 0.10 SPATA24
 spermatogenesis associated 24
 643
 0.54
chr7_101723621_101723772 0.10 CTA-357J21.1
47393
 0.15
chr2_15282512_15282709 0.10 NBAS
 neuroblastoma amplified sequence
 47911
 0.2
chr2_196531011_196531162 0.10 ENSG00000201813
 .
 4112
 0.27
chr3_32451109_32451284 0.10 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 17665
 0.23
chr6_14094353_14094642 0.10 CD83
 CD83 molecule
 23375
 0.24
chr11_14994041_14994192 0.10 CALCA
 calcitonin-related polypeptide alpha
 216
 0.96
chr3_142995226_142995377 0.10 RP13-635I23.3
37970
 0.17
chr7_6183718_6183869 0.10 USP42
 ubiquitin specific peptidase 42
 27682
 0.11
chr10_22629149_22629300 0.10 SPAG6
 sperm associated antigen 6
 5175
 0.17
chr7_26206357_26206508 0.09 CTB-119C2.1
8133
 0.18
chr5_179453537_179453707 0.09 ENSG00000198995
 .
 11225
 0.19
chr7_95916382_95916744 0.09 ENSG00000220987
 .
 19609
 0.16
chr2_64957617_64958033 0.09 ENSG00000253082
 .
 45413
 0.14
chr12_56731704_56731855 0.09 IL23A
 interleukin 23, alpha subunit p19
 884
 0.33
chr1_243607561_243607712 0.09 ENSG00000265201
 .
 98158
 0.07
chr16_87469163_87469969 0.09 ZCCHC14
 zinc finger, CCHC domain containing 14
 2826
 0.22
chr15_84977138_84977289 0.09 UBE2Q2P11
 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 11
 678
 0.57
chr11_930105_930418 0.09 AP2A2
 adaptor-related protein complex 2, alpha 2 subunit
 2432
 0.17
chr17_18528921_18529072 0.09 CCDC144B
 coiled-coil domain containing 144B (pseudogene)
 75
 0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0032634 interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism