Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo
CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for CREB5_CREM_JUNB

Z-value: 0.95

Motif logo

logo of logo of logo of

Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 CREB5
CREM
ENSG00000095794.15 CREM
JUNB
ENSG00000171223.4 JUNB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
CREB5chr7_28725973_287261244500.9056930.854.0e-03Click!
CREB5chr7_28647428_2864757911750.6612540.809.3e-03Click!
CREB5chr7_28893632_28893840447100.1828830.791.1e-02Click!
CREB5chr7_28893326_28893622444480.1837450.781.3e-02Click!
CREB5chr7_28450467_2845067415640.5589900.771.5e-02Click!
CREMchr10_35417017_354173567810.4691780.618.4e-02Click!
CREMchr10_35418232_3541838319020.239169-0.511.6e-01Click!
CREMchr10_35454351_3545450220180.269871-0.481.9e-01Click!
CREMchr10_35438600_3543875113750.3615200.422.6e-01Click!
CREMchr10_35484071_354844141670.9380500.383.2e-01Click!
JUNBchr19_12904796_1290494725610.0949190.836.0e-03Click!
JUNBchr19_12901212_129020017040.3807160.791.2e-02Click!
JUNBchr19_12903336_1290348711010.2278870.713.4e-02Click!
JUNBchr19_12903631_1290378213960.1723470.627.8e-02Click!
JUNBchr19_12902017_129021682180.8058740.551.3e-01Click!

Activity of the CREB5_CREM_JUNB motif across conditions

Conditions sorted by the z-value of the CREB5_CREM_JUNB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_133022629_133022780 1.21 MUC8
 mucin 8
 28022
 0.17
chr1_11901364_11901515 0.65 NPPA-AS1
 NPPA antisense RNA 1
 365
 0.78
chr7_100782348_100782499 0.43 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 12044
 0.1
chr10_6959147_6959298 0.43 PRKCQ
 protein kinase C, theta
 336959
 0.01
chr4_153913148_153913299 0.42 FHDC1
 FH2 domain containing 1
 49088
 0.16
chr3_134092582_134092733 0.41 AMOTL2
 angiomotin like 2
 18
 0.98
chr11_12695755_12695947 0.39 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 118
 0.98
chr1_111033550_111033701 0.38 KCNA10
 potassium voltage-gated channel, shaker-related subfamily, member 10
 28172
 0.13
chr13_45343452_45343641 0.38 ENSG00000238932
 .
 140737
 0.04
chr17_55446479_55446630 0.38 ENSG00000263902
 .
 43008
 0.17
chr18_20840672_20840823 0.37 RP11-17J14.2
429
 0.89
chr15_94850174_94850340 0.37 MCTP2
 multiple C2 domains, transmembrane 2
 8762
 0.33
chr8_49838453_49838744 0.35 SNAI2
 snail family zinc finger 2
 4299
 0.35
chr12_102872919_102873119 0.35 IGF1
 insulin-like growth factor 1 (somatomedin C)
 590
 0.85
chr18_22820121_22820315 0.35 ZNF521
 zinc finger protein 521
 8724
 0.3
chr6_80714655_80715350 0.34 TTK
 TTK protein kinase
 451
 0.88
chr2_38762873_38763024 0.34 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 34030
 0.18
chr1_161274764_161274974 0.33 MPZ
 myelin protein zero
 2392
 0.18
chr9_137348457_137348644 0.33 RXRA
 retinoid X receptor, alpha
 50122
 0.15
chr12_89511566_89511717 0.32 ENSG00000238302
 .
 164421
 0.04
chr1_205216416_205216567 0.32 TMCC2
 transmembrane and coiled-coil domain family 2
 743
 0.63
chr19_35849271_35849508 0.29 FFAR3
 free fatty acid receptor 3
 27
 0.95
chr11_65256298_65256486 0.29 AP000769.1
 Uncharacterized protein
 33664
 0.08
chr5_88566884_88567035 0.28 MEF2C-AS1
 MEF2C antisense RNA 1
 147665
 0.05
chrY_2576678_2576907 0.28 ENSG00000251841
 .
 75998
 0.11
chr3_141514797_141515122 0.27 ENSG00000265391
 .
 8206
 0.2
chr2_11888981_11889322 0.27 LPIN1
 lipin 1
 2387
 0.21
chr11_59279292_59279443 0.27 OR4D9
 olfactory receptor, family 4, subfamily D, member 9
 3019
 0.16
chr13_97876107_97876342 0.27 MBNL2
 muscleblind-like splicing regulator 2
 1615
 0.53
chr1_66999113_66999318 0.27 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 60
 0.98
chr22_44569121_44569281 0.27 PARVG
 parvin, gamma
 365
 0.92
chr4_174198585_174198817 0.26 ENSG00000221296
 .
 9390
 0.17
chr2_29537156_29537327 0.26 ALK
 anaplastic lymphoma receptor tyrosine kinase
 90981
 0.08
chr22_30662165_30662316 0.25 OSM
 oncostatin M
 433
 0.7
chr16_75587106_75587257 0.25 TMEM231
 transmembrane protein 231
 2955
 0.16
chr4_159131101_159131306 0.24 TMEM144
 transmembrane protein 144
 143
 0.96
chrX_2626678_2626926 0.24 CD99
 CD99 molecule
 17261
 0.2
chr12_53784490_53784671 0.23 SP1
 Sp1 transcription factor
 9494
 0.12
chr5_170739623_170739799 0.22 TLX3
 T-cell leukemia homeobox 3
 3423
 0.23
chr7_5492772_5492923 0.22 TNRC18
 trinucleotide repeat containing 18
 27802
 0.1
chr2_144280347_144280652 0.22 AC096558.1
42141
 0.16
chr12_19389657_19389808 0.22 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 126
 0.97
chr1_2216519_2216670 0.22 RP4-713A8.1
41538
 0.09
chr7_138393128_138393279 0.22 SVOPL
 SVOP-like
 7106
 0.24
chr6_14477462_14477818 0.22 ENSG00000206960
 .
 169126
 0.04
chr9_123346254_123346525 0.21 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
 3952
 0.35
chr6_53213778_53213929 0.21 ELOVL5
 ELOVL fatty acid elongase 5
 48
 0.98
chr9_130912677_130912874 0.21 LCN2
 lipocalin 2
 978
 0.34
chr15_98224143_98224294 0.21 LINC00923
 long intergenic non-protein coding RNA 923
 193562
 0.03
chr15_49336349_49337349 0.21 SECISBP2L
 SECIS binding protein 2-like
 1781
 0.28
chr4_113298543_113298694 0.20 ALPK1
 alpha-kinase 1
 80082
 0.08
chr2_28114153_28114304 0.20 RBKS
 ribokinase
 263
 0.74
chr2_95745044_95745195 0.20 AC103563.9
26198
 0.14
chr4_186316955_186317190 0.20 LRP2BP
 LRP2 binding protein
 19
 0.61
chr17_75531537_75531688 0.19 SEPT9
 septin 9
 53617
 0.12
chr6_119417895_119418107 0.19 FAM184A
 family with sequence similarity 184, member A
 17657
 0.19
chr21_18983750_18984027 0.18 BTG3
 BTG family, member 3
 1274
 0.5
chr18_46557895_46558135 0.18 RP11-15F12.1
7942
 0.2
chr3_50337208_50337424 0.18 HYAL3
 hyaluronoglucosaminidase 3
 417
 0.42
chr1_231173648_231173799 0.18 FAM89A
 family with sequence similarity 89, member A
 2269
 0.26
chr17_27889238_27889394 0.18 RP11-68I3.2
1751
 0.18
chr2_8552253_8552511 0.18 AC011747.7
263514
 0.02
chr1_22380057_22380208 0.18 CDC42
 cell division cycle 42
 342
 0.82
chr12_62861008_62861159 0.17 MON2
 MON2 homolog (S. cerevisiae)
 454
 0.83
chr1_236229504_236229679 0.17 NID1
 nidogen 1
 1129
 0.52
chr2_160471369_160471526 0.17 AC009506.1
360
 0.68
chr16_57770832_57771049 0.17 KATNB1
 katanin p80 (WD repeat containing) subunit B 1
 55
 0.96
chr16_48428377_48428528 0.17 SIAH1
 siah E3 ubiquitin protein ligase 1
 586
 0.72
chr19_996464_996712 0.17 AC004528.1
 Uncharacterized protein
 3013
 0.1
chrY_6954060_6954211 0.17 TBL1Y
 transducin (beta)-like 1, Y-linked
 175408
 0.03
chr5_73730230_73730381 0.16 ENSG00000244326
 .
 116494
 0.06
chr12_54446931_54447133 0.16 HOXC4
 homeobox C4
 629
 0.5
chr12_108958034_108958185 0.16 ISCU
 iron-sulfur cluster assembly enzyme
 1723
 0.27
chr6_158508122_158508351 0.16 SYNJ2
 synaptojanin 2
 9524
 0.2
chr8_65490045_65490217 0.16 RP11-21C4.1
311
 0.91
chr4_8430147_8430298 0.16 ACOX3
 acyl-CoA oxidase 3, pristanoyl
 9
 0.98
chr18_10791557_10791762 0.16 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 11
 0.99
chr10_43474933_43475084 0.16 ENSG00000263795
 .
 18003
 0.25
chr9_86323490_86324000 0.16 RP11-522I20.3
512
 0.52
chr16_16047180_16047331 0.16 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 3821
 0.26
chr17_42423914_42424082 0.16 GRN
 granulin
 1325
 0.25
chr19_38908795_38908946 0.16 RASGRP4
 RAS guanyl releasing protein 4
 7932
 0.09
chr8_6114669_6114820 0.16 RP11-115C21.2
149319
 0.04
chr14_101292334_101292485 0.15 AL117190.2
3128
 0.07
chr18_74205447_74205647 0.15 ZNF516
 zinc finger protein 516
 1599
 0.27
chr21_44937001_44937451 0.15 SIK1
 salt-inducible kinase 1
 90218
 0.08
chr15_40636361_40636512 0.15 C15orf52
 chromosome 15 open reading frame 52
 3268
 0.1
chr2_218027426_218027577 0.15 ENSG00000251849
 .
 13720
 0.27
chr14_71246503_71246654 0.15 MAP3K9
 mitogen-activated protein kinase kinase kinase 9
 3579
 0.34
chr7_1979584_1979735 0.15 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 526
 0.85
chr2_102093131_102093315 0.15 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 2058
 0.43
chr6_90929386_90929701 0.15 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 76918
 0.1
chr9_134516940_134517091 0.15 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 15680
 0.22
chr2_11838198_11838349 0.15 AC106875.1
16686
 0.12
chr1_32810829_32811029 0.14 TSSK3
 testis-specific serine kinase 3
 8126
 0.12
chr20_33146664_33146909 0.14 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 264
 0.91
chr6_138126801_138126952 0.14 RP11-356I2.4
20155
 0.19
chr21_36206001_36206152 0.14 RUNX1
 runt-related transcription factor 1
 53404
 0.16
chr20_45934513_45934664 0.14 ENSG00000265532
 .
 2538
 0.2
chr17_65505786_65506259 0.14 CTD-2653B5.1
14575
 0.17
chr22_39163031_39163182 0.14 SUN2
 Sad1 and UNC84 domain containing 2
 11101
 0.08
chr6_2449367_2449525 0.14 ENSG00000266252
 .
 39577
 0.21
chr5_70751007_70751459 0.14 BDP1
 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
 209
 0.96
chr1_17630639_17630914 0.14 PADI4
 peptidyl arginine deiminase, type IV
 3914
 0.2
chr17_72783237_72783388 0.14 TMEM104
 transmembrane protein 104
 10653
 0.11
chr19_8454744_8454908 0.14 RAB11B
 RAB11B, member RAS oncogene family
 39
 0.64
chr1_28099274_28099549 0.13 STX12
 syntaxin 12
 283
 0.78
chr16_73072287_73072438 0.13 ZFHX3
 zinc finger homeobox 3
 9912
 0.21
chr5_66492437_66492594 0.13 CD180
 CD180 molecule
 112
 0.98
chr3_128195185_128195336 0.13 DNAJB8
 DnaJ (Hsp40) homolog, subfamily B, member 8
 9169
 0.15
chr16_22825426_22825577 0.13 HS3ST2
 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
 3
 0.99
chr2_65309092_65309434 0.13 RAB1A
 RAB1A, member RAS oncogene family
 24261
 0.15
chr2_70750633_70750894 0.13 TGFA
 transforming growth factor, alpha
 29859
 0.16
chr5_64331605_64331756 0.13 ENSG00000207439
 .
 87516
 0.1
chr20_62580456_62580607 0.13 UCKL1
 uridine-cytidine kinase 1-like 1
 1948
 0.13
chr8_125726263_125726555 0.13 MTSS1
 metastasis suppressor 1
 13448
 0.25
chr4_141015090_141015375 0.13 RP11-392B6.1
33937
 0.2
chr7_132095239_132095390 0.13 AC011625.1
58221
 0.15
chr21_36295704_36295877 0.13 RUNX1
 runt-related transcription factor 1
 33703
 0.24
chr1_206235900_206236051 0.13 AVPR1B
 arginine vasopressin receptor 1B
 11999
 0.16
chr1_15433135_15433286 0.12 TMEM51
 transmembrane protein 51
 45818
 0.16
chr2_171210862_171211026 0.12 AC012594.1
3316
 0.37
chr4_154713480_154713740 0.12 SFRP2
 secreted frizzled-related protein 2
 3338
 0.26
chr15_70821207_70821700 0.12 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 173167
 0.03
chr16_58535345_58535501 0.12 NDRG4
 NDRG family member 4
 16
 0.97
chr19_4584744_4584943 0.12 SEMA6B
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 25023
 0.09
chr9_114288073_114288445 0.12 ZNF483
 zinc finger protein 483
 746
 0.65
chr12_78813400_78813551 0.12 NAV3
 neuron navigator 3
 220619
 0.02
chr8_146012726_146012877 0.12 ZNF34
 zinc finger protein 34
 71
 0.94
chr21_43673739_43673890 0.12 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 2380
 0.26
chr19_44087068_44087219 0.12 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
 1954
 0.14
chr10_43429375_43429752 0.12 ENSG00000263795
 .
 63448
 0.12
chr7_142216694_142216845 0.12 MTRNR2L6
 MT-RNR2-like 6
 157335
 0.04
chr6_108486750_108487194 0.12 OSTM1
 osteopetrosis associated transmembrane protein 1
 72
 0.78
chr20_30192135_30192286 0.12 ID1
 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
 876
 0.44
chr9_78990142_78990293 0.12 RFK
 riboflavin kinase
 18831
 0.24
chr14_75801482_75801633 0.11 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 54661
 0.1
chr15_80365699_80365932 0.11 ZFAND6
 zinc finger, AN1-type domain 6
 883
 0.66
chr10_121580538_121580689 0.11 INPP5F
 inositol polyphosphate-5-phosphatase F
 2385
 0.32
chr1_151254019_151254394 0.11 ZNF687
 zinc finger protein 687
 112
 0.61
chr2_44345424_44345575 0.11 ENSG00000252599
 .
 36535
 0.15
chr13_113664073_113664237 0.11 RP11-120K24.5
170
 0.9
chr19_6552264_6552452 0.11 ENSG00000199223
 .
 20710
 0.1
chr2_110013073_110013224 0.11 ENSG00000265965
 .
 83067
 0.11
chrX_129318276_129318427 0.11 RAB33A
 RAB33A, member RAS oncogene family
 12728
 0.19
chr2_66723271_66723422 0.11 MEIS1
 Meis homeobox 1
 12713
 0.22
chr3_62304486_62304637 0.11 ENSG00000241472
 .
 6
 0.57
chr2_111453217_111453510 0.11 BUB1
 BUB1 mitotic checkpoint serine/threonine kinase
 17672
 0.21
chr2_1609070_1609221 0.11 AC144450.1
14740
 0.26
chr18_60859816_60859967 0.11 ENSG00000238988
 .
 2007
 0.39
chr2_197944933_197945147 0.11 ANKRD44
 ankyrin repeat domain 44
 30528
 0.22
chr10_71992203_71992435 0.11 PPA1
 pyrophosphatase (inorganic) 1
 841
 0.65
chr10_12379442_12379593 0.11 ENSG00000264036
 .
 9129
 0.18
chr9_137263810_137263961 0.11 ENSG00000263897
 .
 7372
 0.25
chr6_44355096_44355314 0.11 CDC5L
 cell division cycle 5-like
 57
 0.97
chr2_219434859_219435206 0.11 RQCD1
 RCD1 required for cell differentiation1 homolog (S. pombe)
 1434
 0.25
chr1_151809393_151809571 0.11 C2CD4D
 C2 calcium-dependent domain containing 4D
 3551
 0.1
chr2_62520408_62520559 0.11 ENSG00000238809
 .
 28353
 0.17
chr1_167193026_167193202 0.11 POU2F1
 POU class 2 homeobox 1
 2971
 0.23
chrX_83757427_83757578 0.11 HDX
 highly divergent homeobox
 15
 0.51
chr4_174443398_174443549 0.10 HAND2-AS1
 HAND2 antisense RNA 1 (head to head)
 4948
 0.23
chr14_102785720_102785871 0.10 ZNF839
 zinc finger protein 839
 160
 0.94
chr20_17207212_17207363 0.10 PCSK2
 proprotein convertase subtilisin/kexin type 2
 349
 0.9
chr2_47213208_47213406 0.10 RP11-15I20.1
29280
 0.14
chr1_172189218_172189369 0.10 DNM3OS
 DNM3 opposite strand/antisense RNA
 75359
 0.09
chr3_122513525_122513727 0.10 DIRC2
 disrupted in renal carcinoma 2
 16
 0.96
chr2_203735601_203735829 0.10 ICA1L
 islet cell autoantigen 1,69kDa-like
 54
 0.98
chr3_8543150_8543354 0.10 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 32
 0.64
chr19_49142340_49142538 0.10 CA11
 carbonic anhydrase XI
 277
 0.77
chr2_8144515_8144736 0.10 ENSG00000221255
 .
 427653
 0.01
chr2_28837076_28837338 0.10 PLB1
 phospholipase B1
 12421
 0.21
chr3_185080983_185081411 0.10 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
 289
 0.93
chr18_3712580_3712731 0.10 RP11-874J12.3
58775
 0.1
chr8_67343364_67343686 0.10 ADHFE1
 alcohol dehydrogenase, iron containing, 1
 1105
 0.48
chr3_115231996_115232281 0.10 GAP43
 growth associated protein 43
 110033
 0.07
chr8_38385040_38385321 0.10 C8orf86
 chromosome 8 open reading frame 86
 995
 0.59
chr14_81736950_81737101 0.10 STON2
 stonin 2
 6252
 0.26
chr10_1296680_1296831 0.10 ADARB2
 adenosine deaminase, RNA-specific, B2 (non-functional)
 50430
 0.16
chr7_138914973_138915166 0.10 UBN2
 ubinuclein 2
 33
 0.98
chr12_4229354_4229505 0.10 CCND2
 cyclin D2
 153509
 0.04
chr5_138738832_138739361 0.10 SPATA24
 spermatogenesis associated 24
 643
 0.54
chr7_101723621_101723772 0.10 CTA-357J21.1
47393
 0.15
chr2_15282512_15282709 0.10 NBAS
 neuroblastoma amplified sequence
 47911
 0.2
chr2_196531011_196531162 0.10 ENSG00000201813
 .
 4112
 0.27
chr3_32451109_32451284 0.10 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 17665
 0.23
chr6_14094353_14094642 0.10 CD83
 CD83 molecule
 23375
 0.24
chr11_14994041_14994192 0.10 CALCA
 calcitonin-related polypeptide alpha
 216
 0.96
chr3_142995226_142995377 0.10 RP13-635I23.3
37970
 0.17
chr7_6183718_6183869 0.10 USP42
 ubiquitin specific peptidase 42
 27682
 0.11
chr10_22629149_22629300 0.10 SPAG6
 sperm associated antigen 6
 5175
 0.17
chr7_26206357_26206508 0.09 CTB-119C2.1
8133
 0.18
chr5_179453537_179453707 0.09 ENSG00000198995
 .
 11225
 0.19
chr7_95916382_95916744 0.09 ENSG00000220987
 .
 19609
 0.16
chr2_64957617_64958033 0.09 ENSG00000253082
 .
 45413
 0.14
chr12_56731704_56731855 0.09 IL23A
 interleukin 23, alpha subunit p19
 884
 0.33
chr1_243607561_243607712 0.09 ENSG00000265201
 .
 98158
 0.07
chr16_87469163_87469969 0.09 ZCCHC14
 zinc finger, CCHC domain containing 14
 2826
 0.22
chr15_84977138_84977289 0.09 UBE2Q2P11
 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 11
 678
 0.57
chr11_930105_930418 0.09 AP2A2
 adaptor-related protein complex 2, alpha 2 subunit
 2432
 0.17
chr17_18528921_18529072 0.09 CCDC144B
 coiled-coil domain containing 144B (pseudogene)
 75
 0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0032634 interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism