Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for CUX1

Z-value: 0.72

Motif logo

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
ENSG00000257923.5 cut like homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_101388868_101389019CUX1700160.1052920.732.6e-02Click!
chr7_101378437_101378588CUX1804470.0891670.665.5e-02Click!
chr7_101438358_101438509CUX1205260.207993-0.608.5e-02Click!
chr7_101376791_101377001CUX1820630.0869070.571.1e-01Click!
chr7_101387918_101388069CUX1709660.1037090.561.2e-01Click!

Activity of the CUX1 motif across conditions

Conditions sorted by the z-value of the CUX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_4356829_4357115 0.12 ADRA1D
adrenoceptor alpha 1D
127251
0.05
chr6_89504471_89504714 0.12 ENSG00000222145
.
80443
0.1
chr5_102780141_102780414 0.12 NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
118213
0.06
chr5_77887462_77888069 0.11 LHFPL2
lipoma HMGIC fusion partner-like 2
42791
0.21
chr7_114628946_114629097 0.11 MDFIC
MyoD family inhibitor domain containing
55097
0.17
chr22_20777294_20777549 0.11 ENSG00000207343
.
6232
0.12
chr10_33529675_33530002 0.11 NRP1
neuropilin 1
22794
0.19
chr7_100411285_100411882 0.11 ENSG00000263672
.
7303
0.11
chr14_77511448_77512058 0.11 IRF2BPL
interferon regulatory factor 2 binding protein-like
16719
0.18
chr12_66322607_66323042 0.10 AC090673.2
Uncharacterized protein
4857
0.21
chr15_39696001_39696152 0.10 RP11-624L4.1

16834
0.27
chr2_113594705_113594960 0.10 IL1B
interleukin 1, beta
352
0.86
chr21_40378291_40378490 0.10 ENSG00000272015
.
111681
0.06
chr21_47485945_47486454 0.10 AP001471.1

31245
0.13
chr4_186651858_186652115 0.10 SORBS2
sorbin and SH3 domain containing 2
9498
0.21
chr5_159107_159571 0.09 ENSG00000199540
.
15027
0.14
chr7_54878481_54878866 0.09 SEC61G
Sec61 gamma subunit
51006
0.13
chr11_73174890_73175041 0.09 RP11-809N8.4

58623
0.1
chr6_136434664_136434859 0.09 PDE7B
phosphodiesterase 7B
35463
0.16
chr9_110037719_110038006 0.09 RAD23B
RAD23 homolog B (S. cerevisiae)
7556
0.31
chr1_245951430_245951581 0.09 RP11-522M21.3

111725
0.07
chr1_110476345_110476632 0.09 CSF1
colony stimulating factor 1 (macrophage)
22880
0.15
chr6_130644268_130644419 0.09 SAMD3
sterile alpha motif domain containing 3
42227
0.17
chr11_128442939_128443342 0.09 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
14313
0.23
chr9_16031542_16031875 0.09 C9orf92
chromosome 9 open reading frame 92
184189
0.03
chr20_11229977_11230245 0.09 C20orf187
chromosome 20 open reading frame 187
221300
0.02
chr17_26793910_26794378 0.09 SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
6167
0.11
chr12_6198255_6198797 0.09 ENSG00000240533
.
6610
0.23
chr18_46354811_46355214 0.09 RP11-484L8.1

6129
0.29
chr7_2867050_2867285 0.08 GNA12
guanine nucleotide binding protein (G protein) alpha 12
12274
0.25
chr7_132004161_132004312 0.08 AC011625.1

32857
0.21
chr2_48795884_48796035 0.08 STON1-GTF2A1L
STON1-GTF2A1L readthrough
200
0.95
chr10_45476507_45476680 0.08 C10orf10
chromosome 10 open reading frame 10
2335
0.19
chr12_95597054_95597379 0.08 FGD6
FYVE, RhoGEF and PH domain containing 6
13939
0.18
chr2_121005547_121005698 0.08 RALB
v-ral simian leukemia viral oncogene homolog B
4712
0.21
chr4_140933484_140933746 0.08 RP11-392B6.1

115554
0.06
chr18_10479454_10479605 0.08 APCDD1
adenomatosis polyposis coli down-regulated 1
7696
0.26
chr1_66478233_66478531 0.08 PDE4B
phosphodiesterase 4B, cAMP-specific
20277
0.22
chr10_103295849_103296000 0.08 DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
34482
0.14
chr10_88162815_88162966 0.08 GRID1
glutamate receptor, ionotropic, delta 1
36655
0.16
chr3_38871334_38871622 0.08 RP11-134J21.1

6085
0.2
chr10_112182641_112182792 0.08 ENSG00000221359
.
11283
0.22
chr5_94742657_94743120 0.08 FAM81B
family with sequence similarity 81, member B
15840
0.25
chr9_131905468_131905894 0.08 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
1377
0.3
chr8_71060509_71060843 0.08 NCOA2
nuclear receptor coactivator 2
19
0.98
chr19_54023625_54024053 0.08 ZNF331
zinc finger protein 331
439
0.74
chr2_30834318_30834573 0.08 LCLAT1
lysocardiolipin acyltransferase 1
164176
0.04
chr2_216765021_216765281 0.08 ENSG00000212055
.
21509
0.25
chr22_22191485_22191760 0.08 MAPK1
mitogen-activated protein kinase 1
30108
0.12
chr9_16540961_16541659 0.08 RP11-183I6.2

68124
0.12
chr6_25168636_25168787 0.08 ENSG00000222373
.
23930
0.17
chr17_56582578_56582941 0.08 MTMR4
myotubularin related protein 4
8638
0.12
chr7_148410320_148410484 0.08 CUL1
cullin 1
14398
0.17
chr10_114719872_114720172 0.08 RP11-57H14.2

8388
0.22
chr9_117805131_117805394 0.08 TNC
tenascin C
21929
0.25
chr10_75924551_75924986 0.08 ADK
adenosine kinase
11676
0.2
chr18_43381728_43382214 0.07 SIGLEC15
sialic acid binding Ig-like lectin 15
23506
0.18
chr1_203020776_203021050 0.07 PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
545
0.7
chr16_1521079_1521553 0.07 CLCN7
chloride channel, voltage-sensitive 7
641
0.43
chr2_177508527_177508764 0.07 ENSG00000252027
.
20759
0.27
chr5_94423327_94423550 0.07 MCTP1
multiple C2 domains, transmembrane 1
5850
0.32
chr3_10018102_10018700 0.07 EMC3
ER membrane protein complex subunit 3
9965
0.08
chr3_177549479_177549630 0.07 ENSG00000199858
.
176013
0.03
chr10_97047482_97047633 0.07 PDLIM1
PDZ and LIM domain 1
3224
0.31
chr20_44470840_44471081 0.07 SNX21
sorting nexin family member 21
8185
0.08
chr6_109663929_109664175 0.07 ENSG00000201023
.
37355
0.11
chr14_91305961_91306112 0.07 TTC7B
tetratricopeptide repeat domain 7B
23213
0.24
chr15_59588622_59588914 0.07 RP11-429D19.1

25407
0.13
chr2_8722437_8722588 0.07 AC011747.7

93384
0.09
chr9_94154220_94154371 0.07 AUH
AU RNA binding protein/enoyl-CoA hydratase
30100
0.21
chr7_101360762_101360997 0.07 MYL10
myosin, light chain 10, regulatory
88303
0.08
chr4_74844819_74845072 0.07 PF4
platelet factor 4
2896
0.19
chr6_7151631_7152228 0.07 RREB1
ras responsive element binding protein 1
12451
0.19
chr12_63253482_63253831 0.07 ENSG00000200296
.
8975
0.26
chr4_72271640_72271791 0.07 SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
66945
0.14
chr7_26714510_26714661 0.07 C7orf71
chromosome 7 open reading frame 71
37095
0.2
chr13_27543257_27543411 0.07 USP12-AS1
USP12 antisense RNA 1
193658
0.02
chr10_14654331_14654637 0.07 FAM107B
family with sequence similarity 107, member B
67
0.98
chr1_235243157_235243394 0.07 ENSG00000207181
.
47977
0.13
chr9_110905251_110905592 0.07 ENSG00000222512
.
215788
0.02
chr7_47541782_47542068 0.07 TNS3
tensin 3
21042
0.28
chr1_81698308_81698583 0.07 ENSG00000223026
.
19029
0.27
chr10_3793162_3793446 0.07 RP11-184A2.3

45
0.98
chr2_62638288_62638545 0.07 ENSG00000241625
.
79897
0.09
chr2_171219129_171219280 0.07 AC012594.1

11576
0.29
chr7_149666181_149666332 0.07 ATP6V0E2-AS1
ATP6V0E2 antisense RNA 1
88557
0.08
chr1_9950424_9950885 0.07 CTNNBIP1
catenin, beta interacting protein 1
2641
0.21
chr2_224599920_224600071 0.07 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
102206
0.08
chr2_192241823_192241993 0.07 ENSG00000252130
.
6244
0.26
chr8_101450194_101450600 0.07 KB-1615E4.2

37506
0.14
chr2_43188272_43188475 0.07 ENSG00000207087
.
130259
0.05
chr11_85658543_85658752 0.07 RP11-90K17.2

23922
0.18
chr4_140669620_140669850 0.07 ENSG00000252233
.
45852
0.14
chr6_42105086_42105410 0.07 C6orf132
chromosome 6 open reading frame 132
4934
0.17
chr1_85245912_85246495 0.07 ENSG00000251899
.
12679
0.24
chr5_39411390_39411705 0.07 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
13423
0.26
chr1_154703230_154703438 0.07 ADAR
adenosine deaminase, RNA-specific
102860
0.05
chr10_128111271_128111422 0.07 ADAM12
ADAM metallopeptidase domain 12
34322
0.19
chr3_128690038_128690295 0.07 RP11-723O4.6
Uncharacterized protein FLJ43738
7
0.97
chr10_72546347_72546498 0.07 TBATA
thymus, brain and testes associated
1265
0.51
chr3_138493910_138494448 0.07 PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
4782
0.31
chr12_13192614_13192765 0.07 KIAA1467
KIAA1467
4529
0.19
chr9_96902563_96902834 0.07 ENSG00000199165
.
35536
0.13
chr2_207387205_207387356 0.06 ADAM23
ADAM metallopeptidase domain 23
72279
0.1
chr3_141507253_141507404 0.06 ENSG00000265391
.
575
0.76
chr17_56454718_56454869 0.06 SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
24339
0.1
chr2_106088158_106088309 0.06 FHL2
four and a half LIM domains 2
33263
0.2
chr18_10059619_10060204 0.06 ENSG00000263630
.
54717
0.15
chr9_7368414_7368565 0.06 KDM4C
lysine (K)-specific demethylase 4C
354701
0.01
chr2_47284996_47285404 0.06 AC073283.7

9761
0.19
chr22_32272417_32272584 0.06 DEPDC5
DEP domain containing 5
23598
0.15
chr10_43624518_43624697 0.06 CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
9327
0.24
chr3_72536153_72536343 0.06 RYBP
RING1 and YY1 binding protein
40179
0.18
chr1_90289087_90289450 0.06 LRRC8D
leucine rich repeat containing 8 family, member D
1788
0.4
chr1_161691025_161691176 0.06 FCRLB
Fc receptor-like B
253
0.86
chr4_157466044_157466305 0.06 RP11-171N4.2
Uncharacterized protein
97285
0.08
chr16_57798443_57798674 0.06 KIFC3
kinesin family member C3
257
0.89
chr12_11733293_11733560 0.06 ENSG00000251747
.
34013
0.16
chr7_148237394_148237545 0.06 C7orf33
chromosome 7 open reading frame 33
50188
0.15
chr3_11186255_11186406 0.06 HRH1
histamine receptor H1
7551
0.29
chr2_65025641_65026023 0.06 ENSG00000239891
.
18680
0.17
chr15_82420642_82420851 0.06 RP11-597K23.2
Uncharacterized protein
39714
0.14
chr10_115753299_115753721 0.06 ADRB1
adrenoceptor beta 1
50296
0.13
chr4_171593437_171593770 0.06 ENSG00000251961
.
219015
0.02
chr22_37845321_37845613 0.06 ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
21962
0.12
chr8_104122247_104122563 0.06 KB-1639H6.4

10855
0.13
chr12_31515195_31515657 0.06 ENSG00000207477
.
3796
0.2
chr7_5676160_5676311 0.06 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
41918
0.12
chr5_14203788_14204073 0.06 TRIO
trio Rho guanine nucleotide exchange factor
20023
0.29
chr3_51655634_51655948 0.06 RAD54L2
RAD54-like 2 (S. cerevisiae)
7616
0.17
chr9_94579747_94580327 0.06 ROR2
receptor tyrosine kinase-like orphan receptor 2
131125
0.05
chr1_82172157_82172358 0.06 LPHN2
latrophilin 2
6802
0.31
chr5_95630062_95630271 0.06 ENSG00000206997
.
84235
0.09
chr22_46403312_46403647 0.06 WNT7B
wingless-type MMTV integration site family, member 7B
30470
0.1
chr8_98992108_98992483 0.06 MATN2
matrilin 2
18585
0.17
chr15_101656285_101656543 0.06 RP11-505E24.2

30143
0.19
chr4_116135456_116135745 0.06 NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
100568
0.09
chr1_153493498_153493653 0.06 BX470102.3

12504
0.08
chr2_44315981_44316132 0.06 ENSG00000252599
.
65978
0.1
chr2_218793055_218793347 0.06 TNS1
tensin 1
8269
0.24
chr1_152010963_152011114 0.06 S100A11
S100 calcium binding protein A11
1527
0.33
chr10_90188173_90188378 0.06 RNLS
renalase, FAD-dependent amine oxidase
154672
0.04
chr21_40144936_40145370 0.06 ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
32078
0.22
chr2_118981232_118982329 0.06 INSIG2
insulin induced gene 2
135730
0.05
chr10_80714020_80714184 0.06 ZMIZ1-AS1
ZMIZ1 antisense RNA 1
8049
0.31
chr3_5051196_5051347 0.06 BHLHE40-AS1
BHLHE40 antisense RNA 1
29625
0.16
chr2_33714938_33715089 0.06 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
13297
0.26
chr2_65587328_65587537 0.06 SPRED2
sprouty-related, EVH1 domain containing 2
6352
0.24
chr7_105793652_105793945 0.06 SYPL1
synaptophysin-like 1
40776
0.17
chr12_13256087_13256238 0.06 GSG1
germ cell associated 1
414
0.86
chr14_72409694_72409937 0.06 RGS6
regulator of G-protein signaling 6
9866
0.26
chr3_119355128_119355463 0.06 POPDC2
popeye domain containing 2
24142
0.13
chr1_115969093_115969306 0.06 ENSG00000265534
.
59073
0.13
chr3_23780848_23781065 0.06 ENSG00000238672
.
28146
0.18
chr10_108696078_108696229 0.06 ENSG00000200626
.
33626
0.25
chr1_200201358_200201523 0.06 ENSG00000221403
.
87478
0.09
chr4_57157705_57157856 0.06 ENSG00000252489
.
3030
0.25
chr12_65700883_65701407 0.06 MSRB3
methionine sulfoxide reductase B3
19510
0.22
chr8_59507659_59507955 0.06 SDCBP
syndecan binding protein (syntenin)
30232
0.19
chr1_83615938_83616104 0.06 ENSG00000223231
.
643539
0.0
chr8_108395540_108395691 0.06 ANGPT1
angiopoietin 1
46865
0.2
chr12_94821583_94821926 0.06 CCDC41
coiled-coil domain containing 41
31968
0.18
chr11_33905413_33905728 0.06 AC132216.1
HCG1785179; PRO1787; Uncharacterized protein
3381
0.25
chr10_49679111_49679316 0.06 ARHGAP22
Rho GTPase activating protein 22
19543
0.21
chr4_86713761_86713912 0.06 ARHGAP24
Rho GTPase activating protein 24
13977
0.26
chr17_40244674_40244825 0.06 DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
19732
0.09
chr8_25991226_25991377 0.06 ENSG00000199620
.
3095
0.37
chr1_184611707_184611858 0.06 ENSG00000252790
.
35286
0.21
chr10_114817495_114817718 0.06 TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
86073
0.09
chr12_89764903_89765288 0.06 DUSP6
dual specificity phosphatase 6
18047
0.24
chr16_15687209_15687510 0.06 CTB-193M12.1

14972
0.15
chr15_71341987_71342266 0.06 THSD4
thrombospondin, type I, domain containing 4
47165
0.15
chr1_33854701_33854997 0.06 PHC2
polyhomeotic homolog 2 (Drosophila)
13655
0.15
chr10_77468463_77468644 0.06 RP11-367B6.2

33945
0.18
chr16_57671396_57671547 0.06 GPR56
G protein-coupled receptor 56
1736
0.28
chr15_74721212_74721414 0.06 SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
4688
0.16
chr4_8228081_8228232 0.06 SH3TC1
SH3 domain and tetratricopeptide repeats 1
10226
0.22
chr3_123725960_123726111 0.06 ROPN1
rhophilin associated tail protein 1
15010
0.2
chr1_204407416_204407567 0.06 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
26572
0.15
chr10_80176666_80176817 0.06 ENSG00000201393
.
49477
0.19
chr2_165748011_165748162 0.06 ENSG00000223318
.
4201
0.21
chr16_73097967_73098118 0.06 ZFHX3
zinc finger homeobox 3
4445
0.27
chr16_73221207_73221358 0.06 C16orf47
chromosome 16 open reading frame 47
42936
0.2
chr10_14782963_14783114 0.06 FAM107B
family with sequence similarity 107, member B
33858
0.17
chr21_39856205_39856389 0.06 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
14048
0.3
chr17_76140274_76140656 0.06 C17orf99
chromosome 17 open reading frame 99
1969
0.2
chr5_148799600_148799798 0.06 ENSG00000208035
.
8782
0.14
chr1_221334892_221335132 0.06 HLX
H2.0-like homeobox
280428
0.01
chr3_194944977_194945345 0.06 ENSG00000206600
.
9645
0.17
chr2_11837137_11837372 0.06 AC106875.1

15667
0.12
chr7_47497450_47497661 0.06 TNS3
tensin 3
4726
0.35
chr22_35863792_35863943 0.06 MCM5
minichromosome maintenance complex component 5
67443
0.1
chr15_101628578_101628729 0.06 RP11-505E24.2

2382
0.35
chr2_109779392_109779641 0.06 ENSG00000264934
.
21472
0.22
chr8_9018614_9018765 0.06 RP11-10A14.4
Uncharacterized protein
9376
0.17
chr2_152191078_152191290 0.06 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
22922
0.15
chr12_89555329_89555814 0.06 ENSG00000238302
.
120491
0.06
chr17_13447545_13447833 0.06 ENSG00000221698
.
726
0.71
chr4_74975264_74975487 0.06 CXCL2
chemokine (C-X-C motif) ligand 2
10365
0.16
chr2_105271366_105271517 0.06 ENSG00000207249
.
78251
0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0001527 microfibril(GO:0001527)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction