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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for DBP

Z-value: 1.15

Motif logo

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Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
DBP
ENSG00000105516.6 DBP

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
DBPchr19_49137496_491376692010.8523370.646.3e-02Click!
DBPchr19_49134368_4913470632460.1016140.551.2e-01Click!
DBPchr19_49134809_4913496028990.1086540.551.3e-01Click!
DBPchr19_49133609_4913390040290.0914340.343.7e-01Click!
DBPchr19_49133360_4913351143480.0886120.284.6e-01Click!

Activity of the DBP motif across conditions

Conditions sorted by the z-value of the DBP motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_46776893_46777044 0.30 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 8515
 0.15
chr2_217339825_217340365 0.30 AC098820.4
11824
 0.15
chr2_136880193_136880455 0.26 CXCR4
 chemokine (C-X-C motif) receptor 4
 4589
 0.32
chr1_199012180_199012331 0.23 ENSG00000239006
 .
 154057
 0.04
chr17_34619711_34619862 0.22 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
 5933
 0.16
chr6_166658110_166658550 0.21 ENSG00000201292
 .
 35439
 0.16
chr17_71663578_71663963 0.21 SDK2
 sidekick cell adhesion molecule 2
 23542
 0.21
chr17_33694633_33695079 0.21 SLFN11
 schlafen family member 11
 5770
 0.2
chr10_23828998_23829406 0.21 OTUD1
 OTU domain containing 1
 101004
 0.07
chr3_128718043_128718322 0.21 EFCC1
 EF-hand and coiled-coil domain containing 1
 2290
 0.23
chr17_34518155_34518317 0.20 AC131056.3
2908
 0.15
chr17_34606209_34606509 0.20 TBC1D3C
 TBC1 domain family, member 3C
 14327
 0.13
chr17_34411882_34412121 0.20 AC069363.1
3009
 0.13
chr22_32538380_32538635 0.20 AP1B1P1
 adaptor-related protein complex 1, beta 1 subunit pseudogene 1
 10203
 0.14
chr10_105672200_105672613 0.19 OBFC1
 oligonucleotide/oligosaccharide-binding fold containing 1
 5021
 0.2
chr12_9916868_9917340 0.19 CD69
 CD69 molecule
 3607
 0.2
chr4_103656767_103656918 0.19 MANBA
 mannosidase, beta A, lysosomal
 25248
 0.2
chr12_64994089_64994240 0.19 RP11-338E21.1
9075
 0.13
chr15_55539751_55540118 0.18 RAB27A
 RAB27A, member RAS oncogene family
 1299
 0.5
chr18_74835056_74835207 0.18 MBP
 myelin basic protein
 4537
 0.34
chr4_79535031_79535295 0.18 ENSG00000200998
 .
 18376
 0.2
chr6_147091242_147091431 0.18 ADGB
 androglobin
 239
 0.96
chr9_92123694_92124049 0.18 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 10826
 0.22
chr17_47838646_47838824 0.17 FAM117A
 family with sequence similarity 117, member A
 2758
 0.22
chr14_34649904_34650139 0.16 EGLN3
 egl-9 family hypoxia-inducible factor 3
 42062
 0.2
chr2_234318940_234319134 0.16 DGKD
 diacylglycerol kinase, delta 130kDa
 22237
 0.15
chr11_118096084_118096517 0.16 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 491
 0.74
chr2_157327257_157327445 0.16 GPD2
 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
 2733
 0.29
chr8_102212410_102212571 0.16 ZNF706
 zinc finger protein 706
 1395
 0.52
chr19_16704377_16704738 0.16 CTD-3222D19.5
5761
 0.09
chr7_50356212_50356462 0.16 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 8019
 0.29
chr6_166849014_166849195 0.16 RPS6KA2-IT1
 RPS6KA2 intronic transcript 1 (non-protein coding)
 29767
 0.15
chr4_8222732_8223119 0.16 SH3TC1
 SH3 domain and tetratricopeptide repeats 1
 4995
 0.25
chr2_158349915_158350402 0.16 CYTIP
 cytohesin 1 interacting protein
 4685
 0.29
chr2_54817252_54817551 0.16 SPTBN1
 spectrin, beta, non-erythrocytic 1
 31870
 0.16
chr7_12262250_12262487 0.16 TMEM106B
 transmembrane protein 106B
 11419
 0.31
chr16_50719380_50719617 0.16 SNX20
 sorting nexin 20
 4234
 0.14
chr1_200098445_200098816 0.16 ENSG00000221403
 .
 15332
 0.24
chr9_74245405_74245556 0.15 TMEM2
 transmembrane protein 2
 74368
 0.12
chr6_6658591_6658742 0.15 LY86-AS1
 LY86 antisense RNA 1
 35662
 0.21
chr5_122227538_122227689 0.15 SNX24
 sorting nexin 24
 46292
 0.13
chr10_70846687_70847039 0.15 SRGN
 serglycin
 1011
 0.55
chr10_48478469_48478908 0.15 GDF10
 growth differentiation factor 10
 39712
 0.15
chr20_11872259_11872563 0.15 BTBD3
 BTB (POZ) domain containing 3
 436
 0.88
chr1_167596920_167597366 0.15 RCSD1
 RCSD domain containing 1
 2187
 0.29
chr14_89924951_89925223 0.15 FOXN3
 forkhead box N3
 35308
 0.14
chr7_35076257_35076437 0.15 DPY19L1
 dpy-19-like 1 (C. elegans)
 1306
 0.58
chr11_128571263_128571500 0.15 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 5463
 0.2
chr18_74716586_74716828 0.14 MBP
 myelin basic protein
 5371
 0.27
chr19_16228666_16229162 0.14 RAB8A
 RAB8A, member RAS oncogene family
 6207
 0.14
chr17_8859855_8860380 0.14 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 8907
 0.24
chr2_39444415_39444721 0.14 CDKL4
 cyclin-dependent kinase-like 4
 12105
 0.21
chr19_2281233_2281423 0.14 C19orf35
 chromosome 19 open reading frame 35
 847
 0.38
chr18_56382154_56382522 0.14 RP11-126O1.4
37492
 0.12
chr14_20955809_20956004 0.14 PNP
 purine nucleoside phosphorylase
 17221
 0.08
chr17_7238561_7238964 0.14 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 1086
 0.22
chr1_31231275_31231444 0.14 LAPTM5
 lysosomal protein transmembrane 5
 692
 0.66
chr13_31784399_31784550 0.14 B3GALTL
 beta 1,3-galactosyltransferase-like
 10401
 0.27
chr4_55811439_55811670 0.14 ENSG00000264332
 .
 65545
 0.11
chr5_115695176_115695329 0.14 CTB-118N6.3
87991
 0.09
chr6_6611197_6611375 0.14 LY86-AS1
 LY86 antisense RNA 1
 11642
 0.25
chr9_136208045_136208226 0.14 ENSG00000201451
 .
 3474
 0.08
chr22_17588681_17588894 0.14 CECR6
 cat eye syndrome chromosome region, candidate 6
 13356
 0.14
chr3_46342500_46342931 0.14 CCR3
 chemokine (C-C motif) receptor 3
 36096
 0.14
chr17_2695452_2695668 0.14 RAP1GAP2
 RAP1 GTPase activating protein 2
 4172
 0.2
chr7_50353474_50353683 0.14 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 5260
 0.32
chr21_43688719_43689075 0.14 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 12438
 0.16
chr18_52502942_52503093 0.14 RAB27B
 RAB27B, member RAS oncogene family
 7587
 0.27
chr15_94802319_94802604 0.14 MCTP2
 multiple C2 domains, transmembrane 2
 27694
 0.27
chr1_150975197_150975452 0.14 FAM63A
 family with sequence similarity 63, member A
 3637
 0.1
chr16_68109101_68109477 0.14 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
 9958
 0.1
chr22_50838176_50838422 0.14 ENSG00000238604
 .
 1050
 0.38
chr5_150591857_150592074 0.14 GM2A
 GM2 ganglioside activator
 254
 0.92
chr15_31515349_31515542 0.14 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 61969
 0.13
chr13_32609571_32609811 0.14 FRY-AS1
 FRY antisense RNA 1
 3915
 0.26
chr15_88304946_88305195 0.13 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
 171251
 0.04
chr5_107008246_107008397 0.13 EFNA5
 ephrin-A5
 1725
 0.5
chr2_233924263_233924811 0.13 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 140
 0.96
chr16_46692550_46692750 0.13 RP11-93O14.2
2853
 0.24
chr12_82343405_82343568 0.13 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
 190154
 0.03
chr7_8216722_8216994 0.13 ENSG00000265212
 .
 22206
 0.19
chr9_117701644_117701992 0.13 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 9121
 0.28
chr12_11824151_11824362 0.13 ETV6
 ets variant 6
 21468
 0.25
chr7_37349133_37349657 0.13 ELMO1
 engulfment and cell motility 1
 32972
 0.18
chr12_66661258_66661535 0.13 RP11-335I12.2
10182
 0.16
chr4_68441371_68441728 0.13 STAP1
 signal transducing adaptor family member 1
 17103
 0.2
chr2_111562957_111563362 0.13 ACOXL
 acyl-CoA oxidase-like
 263
 0.95
chr18_60766372_60766612 0.13 RP11-299P2.1
52061
 0.15
chr6_108145921_108146601 0.13 SCML4
 sex comb on midleg-like 4 (Drosophila)
 740
 0.76
chr17_17659846_17659997 0.13 RAI1-AS1
 RAI1 antisense RNA 1
 14214
 0.13
chr5_169706707_169706999 0.13 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 12522
 0.22
chr13_42036238_42036522 0.13 RGCC
 regulator of cell cycle
 4685
 0.18
chr3_18766132_18766453 0.13 ENSG00000228956
 .
 20944
 0.29
chr12_102171783_102172089 0.13 ENSG00000201168
 .
 1656
 0.23
chr7_657809_658035 0.13 AC147651.4
15100
 0.17
chr1_28196447_28196641 0.13 THEMIS2
 thymocyte selection associated family member 2
 2511
 0.17
chr6_139565905_139566056 0.13 RP1-225E12.2
5538
 0.21
chr1_40503504_40503714 0.13 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
 2296
 0.3
chr10_98411356_98411597 0.13 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 17892
 0.19
chr8_142131719_142131931 0.13 DENND3
 DENN/MADD domain containing 3
 4448
 0.23
chr7_8216150_8216370 0.13 ENSG00000265212
 .
 21608
 0.19
chr18_29621140_29621437 0.13 ENSG00000265063
 .
 19664
 0.13
chr1_229162847_229163204 0.13 RP5-1061H20.5
200284
 0.02
chr8_134562977_134563358 0.13 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 20925
 0.27
chr14_90185242_90185495 0.13 ENSG00000200312
 .
 6513
 0.24
chrX_128917643_128917877 0.13 SASH3
 SAM and SH3 domain containing 3
 3800
 0.24
chr1_159868738_159869013 0.13 CCDC19
 coiled-coil domain containing 19
 816
 0.34
chr20_20664895_20665109 0.13 RALGAPA2
 Ral GTPase activating protein, alpha subunit 2 (catalytic)
 28129
 0.23
chr15_70780606_70780757 0.13 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 213939
 0.02
chr9_115627506_115627657 0.13 RP11-408O19.5
19857
 0.17
chr2_68652249_68652409 0.13 FBXO48
 F-box protein 48
 42061
 0.12
chr7_37389453_37389714 0.13 ENSG00000222869
 .
 1164
 0.51
chrX_65267830_65268055 0.13 VSIG4
 V-set and immunoglobulin domain containing 4
 7975
 0.23
chr15_31271292_31271496 0.13 MTMR10
 myotubularin related protein 10
 4802
 0.18
chr10_7526915_7527101 0.13 ENSG00000207453
 .
 1763
 0.44
chr2_136899107_136899528 0.13 CXCR4
 chemokine (C-X-C motif) receptor 4
 23582
 0.25
chr12_8755911_8756062 0.13 AICDA
 activation-induced cytidine deaminase
 3626
 0.16
chr1_207232696_207232912 0.13 PFKFB2
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
 4759
 0.14
chr11_64976530_64976899 0.13 CAPN1
 calpain 1, (mu/I) large subunit
 25907
 0.08
chr15_101071565_101071716 0.13 CERS3
 ceramide synthase 3
 12836
 0.15
chr5_169306526_169306677 0.13 CTB-37A13.1
100232
 0.07
chr8_142414415_142414628 0.13 CTD-3064M3.4
11847
 0.12
chr13_46743886_46744372 0.13 ENSG00000240767
 .
 246
 0.88
chr1_3807311_3807510 0.13 ENSG00000264428
 .
 6782
 0.16
chr10_14348378_14348529 0.13 FRMD4A
 FERM domain containing 4A
 23648
 0.23
chr20_8310366_8310517 0.12 PLCB1-IT1
 PLCB1 intronic transcript 1 (non-protein coding)
 81069
 0.11
chr17_47824587_47824834 0.12 FAM117A
 family with sequence similarity 117, member A
 16783
 0.14
chr15_86251203_86251443 0.12 RP11-815J21.1
6983
 0.12
chr15_63740013_63740164 0.12 USP3
 ubiquitin specific peptidase 3
 56705
 0.13
chr18_52384635_52384905 0.12 RAB27B
 RAB27B, member RAS oncogene family
 321
 0.94
chr1_221884647_221884930 0.12 DUSP10
 dual specificity phosphatase 10
 26014
 0.26
chr1_25361172_25361323 0.12 ENSG00000264371
 .
 11253
 0.23
chr8_125046706_125046857 0.12 RP11-959I15.4
5928
 0.2
chr2_8562176_8562384 0.12 AC011747.7
253616
 0.02
chrX_128904932_128905357 0.12 SASH3
 SAM and SH3 domain containing 3
 8816
 0.2
chr3_112183882_112184126 0.12 BTLA
 B and T lymphocyte associated
 34201
 0.19
chr12_111065801_111066057 0.12 ENSG00000263537
 .
 2207
 0.23
chr19_2619378_2619607 0.12 CTC-265F19.2
7632
 0.14
chr22_38068883_38069075 0.12 LGALS1
 lectin, galactoside-binding, soluble, 1
 2636
 0.13
chr11_128607706_128608101 0.12 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 26782
 0.17
chr15_63898445_63898817 0.12 USP3-AS1
 USP3 antisense RNA 1
 4843
 0.21
chr8_37731564_37731977 0.12 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 3865
 0.18
chr20_57829512_57829876 0.12 EDN3
 endothelin 3
 45788
 0.15
chr14_91845514_91845690 0.12 CCDC88C
 coiled-coil domain containing 88C
 38088
 0.16
chr20_19314143_19314471 0.12 ENSG00000221748
 .
 7633
 0.26
chr11_33255190_33255341 0.12 HIPK3
 homeodomain interacting protein kinase 3
 22953
 0.17
chr6_91060753_91061282 0.12 ENSG00000266760
 .
 38556
 0.18
chr17_45781212_45781384 0.12 TBKBP1
 TBK1 binding protein 1
 8668
 0.14
chr2_64695090_64695299 0.12 LGALSL
 lectin, galactoside-binding-like
 13518
 0.19
chr3_12503836_12504037 0.12 TSEN2
 TSEN2 tRNA splicing endonuclease subunit
 21995
 0.15
chr13_60026787_60027144 0.12 ENSG00000239003
 .
 27239
 0.28
chr16_50743382_50743603 0.12 NOD2
 nucleotide-binding oligomerization domain containing 2
 2613
 0.16
chr10_73535863_73536136 0.12 C10orf54
 chromosome 10 open reading frame 54
 2744
 0.26
chr21_47788798_47788949 0.12 PCNT
 pericentrin
 44837
 0.1
chr22_17578526_17578936 0.12 IL17RA
 interleukin 17 receptor A
 12882
 0.15
chr3_195277399_195277835 0.12 AC091633.3
4198
 0.18
chr1_108586650_108587048 0.12 ENSG00000264753
 .
 25456
 0.21
chrX_138636733_138636884 0.12 F9
 coagulation factor IX
 23884
 0.2
chr1_26616916_26617250 0.12 SH3BGRL3
 SH3 domain binding glutamic acid-rich protein like 3
 10470
 0.11
chr10_26667989_26668241 0.12 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
 59017
 0.15
chr1_154376165_154376624 0.12 IL6R
 interleukin 6 receptor
 1275
 0.33
chr17_72726639_72727007 0.12 RAB37
 RAB37, member RAS oncogene family
 5914
 0.11
chr10_6607286_6607516 0.12 PRKCQ
 protein kinase C, theta
 14800
 0.3
chr1_92925228_92925479 0.12 GFI1
 growth factor independent 1 transcription repressor
 24158
 0.21
chr12_69742182_69742355 0.12 LYZ
 lysozyme
 102
 0.96
chr1_40308954_40309106 0.12 ENSG00000202222
 .
 38320
 0.09
chr1_36922243_36922595 0.12 OSCP1
 organic solute carrier partner 1
 6333
 0.14
chr2_136893672_136893831 0.12 CXCR4
 chemokine (C-X-C motif) receptor 4
 18016
 0.27
chr7_38349303_38349454 0.12 STARD3NL
 STARD3 N-terminal like
 131381
 0.05
chr5_118643731_118644037 0.12 ENSG00000243333
 .
 1558
 0.41
chr2_148806923_148807074 0.12 ORC4
 origin recognition complex, subunit 4
 27851
 0.19
chr2_240162756_240163017 0.12 HDAC4
 histone deacetylase 4
 50134
 0.11
chrX_70391376_70391679 0.12 RP5-1091N2.9
26498
 0.1
chr5_86375411_86375667 0.12 ENSG00000251951
 .
 23124
 0.21
chr7_157182751_157183382 0.12 DNAJB6
 DnaJ (Hsp40) homolog, subfamily B, member 6
 50551
 0.15
chr2_74268024_74268228 0.12 TET3
 tet methylcytosine dioxygenase 3
 5324
 0.2
chr5_40670687_40670879 0.12 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
 8817
 0.21
chr3_30644339_30644515 0.12 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 3567
 0.37
chr12_29362316_29362582 0.12 FAR2
 fatty acyl CoA reductase 2
 14149
 0.26
chr8_119121685_119121918 0.12 EXT1
 exostosin glycosyltransferase 1
 852
 0.77
chr11_121340734_121341098 0.12 RP11-730K11.1
17194
 0.23
chr2_70667703_70667865 0.12 ENSG00000215996
 .
 14972
 0.15
chr11_48044517_48044998 0.12 AC103828.1
7350
 0.22
chr22_19084512_19084678 0.12 AC004471.9
24447
 0.1
chr15_70007265_70007861 0.12 ENSG00000238870
 .
 15598
 0.26
chr7_96467239_96467390 0.12 ENSG00000244318
 .
 102362
 0.07
chr17_55358360_55358511 0.12 MSI2
 musashi RNA-binding protein 2
 4770
 0.31
chr20_45181455_45181613 0.12 OCSTAMP
 osteoclast stimulatory transmembrane protein
 2321
 0.32
chr7_114776119_114776270 0.12 ENSG00000199764
 .
 71856
 0.13
chr3_16887733_16887892 0.12 PLCL2
 phospholipase C-like 2
 38640
 0.2
chr14_89819638_89820075 0.12 RP11-356K23.2
1548
 0.36
chr2_8007405_8007668 0.12 ENSG00000221255
 .
 290564
 0.01
chr17_28275822_28275973 0.12 EFCAB5
 EF-hand calcium binding domain 5
 7274
 0.16
chr7_130056827_130057089 0.12 CEP41
 centrosomal protein 41kDa
 215
 0.92
chr15_92401739_92402176 0.12 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 4606
 0.29
chr6_24950964_24951248 0.12 FAM65B
 family with sequence similarity 65, member B
 14918
 0.22
chr8_130600986_130601137 0.12 ENSG00000266387
 .
 91148
 0.06
chr20_4792096_4792247 0.12 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 3598
 0.25
chr7_139314548_139314773 0.12 CLEC2L
 C-type lectin domain family 2, member L
 105832
 0.06
chr13_33562441_33562592 0.12 KL
 klotho
 27691
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.2 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0032616 interleukin-13 production(GO:0032616)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0002883 hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0072505 phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.2 GO:0070664 negative regulation of leukocyte proliferation(GO:0070664)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.4 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters