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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for DLX3_EVX1_MEOX1

Z-value: 0.49

Motif logo

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Transcription factors associated with DLX3_EVX1_MEOX1

Gene Symbol Gene ID Gene Info
ENSG00000064195.7 distal-less homeobox 3
ENSG00000106038.8 even-skipped homeobox 1
ENSG00000005102.8 mesenchyme homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_48072953_48073104DLX34400.786378-0.531.4e-01Click!
chr17_48098459_48098610DLX3259460.117708-0.511.6e-01Click!
chr17_48065557_48065736DLX354210.160487-0.452.3e-01Click!
chr17_48066991_48067142DLX340010.176193-0.442.3e-01Click!
chr17_48067814_48067965DLX331780.194847-0.432.5e-01Click!
chr7_27277820_27277971EVX142690.117139-0.872.4e-03Click!
chr7_27265056_27265207EVX1170330.078925-0.609.0e-02Click!
chr7_27264732_27264980EVX1173080.0784080.521.5e-01Click!
chr7_27281956_27282140EVX11160.8434380.304.4e-01Click!
chr7_27275467_27275717EVX165720.1029370.284.6e-01Click!
chr17_41758579_41758730MEOX1193320.152783-0.917.5e-04Click!
chr17_41773724_41773941MEOX1345100.114495-0.853.4e-03Click!
chr17_41774123_41774274MEOX1348760.113573-0.818.1e-03Click!
chr17_41773565_41773716MEOX1343180.114979-0.791.1e-02Click!
chr17_41778897_41779096MEOX1396740.101761-0.771.5e-02Click!

Activity of the DLX3_EVX1_MEOX1 motif across conditions

Conditions sorted by the z-value of the DLX3_EVX1_MEOX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_20015723_20015939 0.29 HTR6
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
24051
0.16
chr2_143918611_143918880 0.29 RP11-190J23.1

10996
0.25
chr13_46893880_46894070 0.29 ENSG00000223336
.
54750
0.1
chr1_200987046_200987749 0.25 KIF21B
kinesin family member 21B
5139
0.21
chr2_43402387_43402951 0.24 ZFP36L2
ZFP36 ring finger protein-like 2
51079
0.14
chr4_78721201_78721381 0.24 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
18926
0.25
chr2_175207474_175207756 0.23 AC018470.1
Uncharacterized protein FLJ46347
5464
0.18
chr8_127567681_127568033 0.23 RP11-103H7.5

1284
0.38
chr13_50144464_50144942 0.21 RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
3244
0.28
chr8_118531704_118531855 0.21 MED30
mediator complex subunit 30
1173
0.66
chr1_25887348_25887770 0.20 LDLRAP1
low density lipoprotein receptor adaptor protein 1
17488
0.19
chr4_14996539_14996690 0.20 CPEB2
cytoplasmic polyadenylation element binding protein 2
7684
0.31
chr1_89338434_89338585 0.18 GTF2B
general transcription factor IIB
18670
0.19
chr14_99665484_99665650 0.18 AL162151.4

40814
0.17
chr3_152898855_152899006 0.18 ENSG00000265813
.
18876
0.19
chr9_71633765_71634208 0.18 PRKACG
protein kinase, cAMP-dependent, catalytic, gamma
4947
0.24
chr8_96174564_96174728 0.17 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
28342
0.18
chrX_154473029_154473180 0.17 RAB39B
RAB39B, member RAS oncogene family
20770
0.15
chr4_140724600_140724880 0.17 ENSG00000252233
.
9153
0.26
chr3_180322342_180322530 0.17 TTC14
tetratricopeptide repeat domain 14
2086
0.3
chr11_94960792_94960943 0.17 RP11-712B9.2

2483
0.31
chr1_168501039_168501303 0.17 XCL2
chemokine (C motif) ligand 2
12064
0.25
chr2_101977462_101977622 0.17 CREG2
cellular repressor of E1A-stimulated genes 2
26515
0.17
chr11_67170134_67170292 0.17 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
811
0.3
chr16_384366_384517 0.16 AXIN1
axin 1
18008
0.1
chr9_130904274_130904425 0.16 LCN2
lipocalin 2
7001
0.09
chr6_4790828_4790979 0.16 CDYL
chromodomain protein, Y-like
14234
0.22
chr2_204726088_204726239 0.16 CTLA4
cytotoxic T-lymphocyte-associated protein 4
6346
0.27
chr12_111613238_111613505 0.16 CUX2
cut-like homeobox 2
76121
0.1
chr1_100821699_100821850 0.16 CDC14A
cell division cycle 14A
3269
0.24
chr15_91108604_91108755 0.16 CRTC3
CREB regulated transcription coactivator 3
28266
0.14
chr17_42574366_42574517 0.16 GPATCH8
G patch domain containing 8
6318
0.19
chr1_143741628_143741785 0.16 RP6-206I17.4

22002
0.16
chr8_126285678_126285829 0.16 ENSG00000242170
.
2907
0.35
chr1_85354747_85355038 0.15 LPAR3
lysophosphatidic acid receptor 3
4004
0.29
chr14_92973076_92973375 0.15 RIN3
Ras and Rab interactor 3
6893
0.29
chr1_147929159_147929310 0.15 PPIAL4A
peptidylprolyl isomerase A (cyclophilin A)-like 4A
26185
0.15
chr9_33976084_33976235 0.15 UBAP2
ubiquitin associated protein 2
12882
0.13
chr5_130706488_130706854 0.15 CDC42SE2
CDC42 small effector 2
14628
0.29
chr13_41574006_41574157 0.15 ELF1
E74-like factor 1 (ets domain transcription factor)
17663
0.19
chr5_34001933_34002084 0.15 AMACR
alpha-methylacyl-CoA racemase
6125
0.2
chr5_130849058_130849272 0.15 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
5315
0.33
chr1_151996398_151996549 0.15 S100A11
S100 calcium binding protein A11
13038
0.14
chr6_90989536_90989687 0.15 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
16850
0.23
chr2_171985361_171985646 0.15 ENSG00000238567
.
17337
0.23
chr20_50129553_50129706 0.15 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
29629
0.21
chrX_11784442_11784722 0.15 MSL3
male-specific lethal 3 homolog (Drosophila)
6835
0.32
chr17_63024647_63024798 0.15 RP11-583F2.5

23305
0.15
chr19_39127082_39127242 0.15 ACTN4
actinin, alpha 4
11148
0.11
chr8_71111947_71112098 0.15 NCOA2
nuclear receptor coactivator 2
45588
0.17
chr17_75317102_75317253 0.15 SEPT9
septin 9
782
0.69
chr14_99707548_99707699 0.15 AL109767.1

21662
0.2
chr10_126630439_126630590 0.14 ZRANB1
zinc finger, RAN-binding domain containing 1
178
0.94
chr1_169663386_169663580 0.14 SELL
selectin L
17356
0.18
chr1_90290727_90290878 0.14 LRRC8D
leucine rich repeat containing 8 family, member D
3322
0.28
chr1_175124219_175124377 0.14 KIAA0040
KIAA0040
37592
0.18
chr6_16132777_16133009 0.14 MYLIP
myosin regulatory light chain interacting protein
3491
0.22
chr12_93778833_93779048 0.14 NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
6510
0.16
chr8_129566610_129566901 0.14 ENSG00000221351
.
265285
0.02
chr8_96150775_96150926 0.14 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
4546
0.24
chr6_87872093_87872244 0.14 ZNF292
zinc finger protein 292
6829
0.2
chr14_76032303_76032574 0.14 FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
12522
0.16
chr7_21405981_21406526 0.14 ENSG00000195024
.
14728
0.23
chr12_104940888_104941108 0.14 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
41628
0.17
chr20_44634089_44634268 0.14 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
3369
0.16
chr3_56844963_56845119 0.14 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
9046
0.29
chr5_156695529_156695722 0.14 CYFIP2
cytoplasmic FMR1 interacting protein 2
737
0.55
chr10_62954984_62955245 0.14 RHOBTB1
Rho-related BTB domain containing 1
193916
0.03
chr12_47600641_47601211 0.14 PCED1B
PC-esterase domain containing 1B
9126
0.22
chr5_175036653_175036804 0.14 ENSG00000222111
.
18463
0.21
chr15_60107360_60107511 0.14 BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
125702
0.05
chr3_187971650_187971801 0.14 LPP
LIM domain containing preferred translocation partner in lipoma
14073
0.27
chr17_28067929_28068080 0.14 RP11-82O19.1

20117
0.14
chr1_152365758_152366013 0.14 RP1-91G5.3

19455
0.13
chr15_51568678_51568829 0.13 RP11-108K3.3

3459
0.23
chr2_102328256_102328453 0.13 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
13362
0.29
chr7_135655824_135656276 0.13 MTPN
myotrophin
6014
0.18
chr12_12856735_12856886 0.13 GPR19
G protein-coupled receptor 19
7669
0.15
chr18_74805340_74805625 0.13 MBP
myelin basic protein
11735
0.29
chr11_128496159_128496310 0.13 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
38781
0.15
chr7_97792627_97792778 0.13 BHLHA15
basic helix-loop-helix family, member a15
48037
0.13
chr1_115009857_115010035 0.13 TRIM33
tripartite motif containing 33
3898
0.27
chr10_8286078_8286310 0.13 GATA3
GATA binding protein 3
189425
0.03
chr5_39163760_39163964 0.13 FYB
FYN binding protein
39267
0.18
chr2_64342417_64342568 0.13 AC074289.1

27881
0.19
chrX_10126940_10127091 0.13 CLCN4
chloride channel, voltage-sensitive 4
443
0.87
chr12_95196521_95196672 0.13 ENSG00000208038
.
31578
0.23
chr19_39686992_39687200 0.13 NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
505
0.69
chr2_26096243_26096394 0.13 ASXL2
additional sex combs like 2 (Drosophila)
5017
0.29
chr14_99726122_99726406 0.13 AL109767.1

3021
0.29
chr14_96984501_96984733 0.13 PAPOLA
poly(A) polymerase alpha
9162
0.19
chr9_77743638_77743789 0.13 OSTF1
osteoclast stimulating factor 1
40254
0.13
chr14_81998709_81999052 0.13 SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
1297
0.61
chr15_76933945_76934096 0.13 ENSG00000266449
.
55032
0.15
chr2_172008488_172008813 0.13 ENSG00000238567
.
5810
0.25
chr14_68974321_68974560 0.13 RAD51B
RAD51 paralog B
96213
0.08
chr5_173313190_173313341 0.13 CPEB4
cytoplasmic polyadenylation element binding protein 4
2018
0.44
chr11_10822167_10822423 0.13 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
266
0.79
chr3_101440503_101440752 0.13 CEP97
centrosomal protein 97kDa
2142
0.24
chr17_5077650_5077801 0.13 ZNF594
zinc finger protein 594
9967
0.12
chr10_35301342_35301493 0.13 CUL2
cullin 2
58850
0.1
chr1_151024007_151024158 0.13 C1orf56
chromosome 1 open reading frame 56
3866
0.1
chr16_84769322_84769473 0.13 USP10
ubiquitin specific peptidase 10
32474
0.16
chr17_75869292_75869566 0.13 FLJ45079

9230
0.24
chrX_44757083_44757315 0.13 ENSG00000252113
.
12448
0.21
chr12_4394750_4395246 0.13 CCND2-AS1
CCND2 antisense RNA 1
9648
0.16
chr5_56024755_56025049 0.13 MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
86499
0.08
chr13_32616590_32616779 0.13 FRY-AS1
FRY antisense RNA 1
10908
0.22
chrX_19823671_19823848 0.12 SH3KBP1
SH3-domain kinase binding protein 1
5890
0.31
chr7_150329628_150329863 0.12 GIMAP6
GTPase, IMAP family member 6
272
0.92
chr11_60250640_60250791 0.12 MS4A12
membrane-spanning 4-domains, subfamily A, member 12
9536
0.16
chr2_152510948_152511099 0.12 NEB
nebulin
70890
0.13
chr1_223314553_223314781 0.12 TLR5
toll-like receptor 5
1913
0.48
chr6_35700974_35701173 0.12 RP3-510O8.4

3651
0.14
chr7_42962275_42962426 0.12 PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
9423
0.19
chr14_99703175_99703515 0.12 AL109767.1

25940
0.19
chr2_96907290_96907448 0.12 TMEM127
transmembrane protein 127
18964
0.12
chr2_205942725_205942950 0.12 PARD3B
par-3 family cell polarity regulator beta
532114
0.0
chr16_53482763_53482914 0.12 RP11-44F14.5

178
0.9
chr14_38547030_38547196 0.12 CTD-2058B24.2

13250
0.26
chr11_128644263_128644414 0.12 FLI1
Fli-1 proto-oncogene, ETS transcription factor
9653
0.22
chr1_111439380_111439531 0.12 CD53
CD53 molecule
23679
0.15
chr5_75600048_75600202 0.12 RP11-466P24.6

7162
0.3
chr3_137935329_137935480 0.12 ARMC8
armadillo repeat containing 8
7074
0.23
chr3_171130059_171130210 0.12 ENSG00000222506
.
27181
0.21
chr5_159461944_159462095 0.12 TTC1
tetratricopeptide repeat domain 1
8121
0.21
chr22_41251648_41251915 0.12 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
1179
0.3
chr11_118109489_118109640 0.12 MPZL3
myelin protein zero-like 3
13498
0.13
chr20_58625758_58625909 0.12 C20orf197
chromosome 20 open reading frame 197
5147
0.27
chr17_47407103_47407254 0.12 ENSG00000251964
.
3915
0.17
chr6_120063458_120063609 0.12 ENSG00000265725
.
272792
0.02
chr3_52235256_52235407 0.12 ALAS1
aminolevulinate, delta-, synthase 1
3171
0.15
chr18_43236719_43236870 0.12 SLC14A2
solute carrier family 14 (urea transporter), member 2
9313
0.2
chr2_99335771_99335922 0.12 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
7313
0.25
chr14_36988822_36989041 0.12 NKX2-1
NK2 homeobox 1
33
0.88
chr1_87082986_87083335 0.12 ENSG00000221702
.
11120
0.18
chr10_8585757_8585908 0.12 ENSG00000212505
.
112962
0.07
chr6_154555947_154556098 0.12 IPCEF1
interaction protein for cytohesin exchange factors 1
11968
0.31
chr17_4297572_4297951 0.12 UBE2G1
ubiquitin-conjugating enzyme E2G 1
27838
0.13
chr14_65192092_65192622 0.12 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
1858
0.39
chr1_155190483_155190634 0.12 GBAP1
glucosidase, beta, acid pseudogene 1
1893
0.12
chr22_27066729_27066953 0.12 CRYBA4
crystallin, beta A4
48913
0.13
chr13_21048550_21048701 0.12 ENSG00000263978
.
40640
0.16
chr12_44224852_44225136 0.12 TMEM117
transmembrane protein 117
4892
0.24
chr14_98641364_98641616 0.12 ENSG00000222066
.
156597
0.04
chr2_85204305_85204589 0.12 KCMF1
potassium channel modulatory factor 1
5123
0.25
chr12_117959445_117959596 0.12 RP11-227B21.2

68703
0.13
chr7_37011204_37011355 0.12 ELMO1
engulfment and cell motility 1
13386
0.2
chr6_159223106_159223347 0.12 EZR-AS1
EZR antisense RNA 1
15817
0.16
chr5_140864104_140864255 0.12 PCDHGC4
protocadherin gamma subfamily C, 4
562
0.55
chr6_119226723_119226983 0.12 ASF1A
anti-silencing function 1A histone chaperone
11469
0.19
chr16_73092870_73093114 0.11 ZFHX3
zinc finger homeobox 3
605
0.79
chr2_174756889_174757040 0.11 SP3
Sp3 transcription factor
71983
0.13
chr7_105919723_105919874 0.11 NAMPT
nicotinamide phosphoribosyltransferase
5569
0.23
chr3_41245206_41245357 0.11 CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
3679
0.39
chr11_48078680_48078903 0.11 ENSG00000263693
.
39543
0.14
chr1_121295339_121295490 0.11 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
359477
0.01
chr4_38518191_38518342 0.11 RP11-617D20.1

107930
0.07
chr12_46614859_46615010 0.11 SLC38A1
solute carrier family 38, member 1
46550
0.19
chr20_56969877_56970028 0.11 VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
5583
0.26
chr1_235439552_235439703 0.11 GGPS1
geranylgeranyl diphosphate synthase 1
51038
0.11
chr1_172597329_172597480 0.11 ENSG00000251943
.
14730
0.22
chr9_92078215_92078535 0.11 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
7507
0.25
chr13_49484698_49484849 0.11 ENSG00000265585
.
19575
0.22
chr19_6065223_6065413 0.11 CTC-232P5.3

2646
0.21
chr15_83733229_83733380 0.11 BTBD1
BTB (POZ) domain containing 1
2599
0.17
chr1_200121942_200122869 0.11 ENSG00000221403
.
8443
0.27
chr1_224026385_224026536 0.11 TP53BP2
tumor protein p53 binding protein, 2
7172
0.28
chr1_91481513_91481868 0.11 ZNF644
zinc finger protein 644
5324
0.35
chr1_113383632_113383813 0.11 SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
94888
0.06
chr9_134504383_134504534 0.11 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
3123
0.3
chr3_186518618_186518769 0.11 RFC4
replication factor C (activator 1) 4, 37kDa
3820
0.09
chr5_40674108_40674292 0.11 PTGER4
prostaglandin E receptor 4 (subtype EP4)
5400
0.23
chr3_187644954_187645105 0.11 BCL6
B-cell CLL/lymphoma 6
181514
0.03
chr7_32886085_32886236 0.11 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
44605
0.14
chr6_56109453_56109604 0.11 COL21A1
collagen, type XXI, alpha 1
2707
0.4
chr5_68339437_68339588 0.11 SLC30A5
solute carrier family 30 (zinc transporter), member 5
49961
0.12
chr19_47948776_47948927 0.11 MEIS3
Meis homeobox 3
26071
0.11
chr9_15500835_15500986 0.11 PSIP1
PC4 and SFRS1 interacting protein 1
9377
0.17
chr1_32447200_32447431 0.11 KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
32115
0.13
chr19_2624596_2624817 0.11 CTC-265F19.3

7246
0.14
chr8_71132477_71132643 0.11 NCOA2
nuclear receptor coactivator 2
25050
0.23
chr20_21552286_21552437 0.11 NKX2-2
NK2 homeobox 2
57697
0.13
chr5_112215979_112216130 0.11 ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
11259
0.12
chr11_63332130_63332281 0.11 HRASLS2
HRAS-like suppressor 2
1350
0.37
chr9_92032244_92032395 0.11 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
1429
0.51
chr21_17123521_17123672 0.11 USP25
ubiquitin specific peptidase 25
21100
0.21
chr6_70525704_70525879 0.11 LMBRD1
LMBR1 domain containing 1
18788
0.25
chr11_73495057_73495208 0.11 MRPL48
mitochondrial ribosomal protein L48
3229
0.19
chr22_22081173_22081324 0.11 ENSG00000244671
.
3777
0.16
chr4_36256915_36257081 0.11 RP11-431M7.3

1142
0.53
chr4_1710080_1710231 0.11 SLBP
stem-loop binding protein
3590
0.17
chr1_32644341_32644638 0.11 TXLNA
taxilin alpha
798
0.41
chrX_1781946_1782112 0.11 ASMT
acetylserotonin O-methyltransferase
26738
0.22
chrY_1731945_1732112 0.11 ENSG00000251841
.
920762
0.0
chr12_120113093_120113244 0.11 PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
3119
0.22
chr1_192541505_192541656 0.11 RGS1
regulator of G-protein signaling 1
3277
0.26
chr1_109836886_109837045 0.11 PSRC1
proline/serine-rich coiled-coil 1
11157
0.15
chr1_25888465_25889044 0.11 LDLRAP1
low density lipoprotein receptor adaptor protein 1
18683
0.19
chr1_117352258_117352539 0.11 CD2
CD2 molecule
55309
0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX3_EVX1_MEOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.1 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0052167 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0051709 regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling