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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for DMC1

Z-value: 2.12

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Transcription factors associated with DMC1

Gene Symbol	Gene ID	Gene Info
DMC1 Ensembl NCBI GeneCards UniProt	ENSG00000100206.5	DNA meiotic recombinase 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr22_38967574_38967725	DMC1	1358	0.379883	0.66	5.2e-02	Click!
chr22_38964224_38964375	DMC1	115	0.958223	0.49	1.8e-01	Click!
chr22_39002732_39002883	DMC1	36516	0.089830	-0.48	1.9e-01	Click!
chr22_38965558_38966055	DMC1	330	0.863961	-0.46	2.2e-01	Click!
chr22_38966667_38966872	DMC1	478	0.772883	-0.21	5.8e-01	Click!

Activity of the DMC1 motif across conditions

Conditions sorted by the z-value of the DMC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_21657441_21657592	1.00	GOLT1B	golgi transport 1B	2767	0.22
chr21_34934879_34935141	0.97	SON	SON DNA binding protein	7655	0.13
chr16_68150380_68150569	0.92	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	6459	0.13
chr14_102308581_102308732	0.91	CTD-2017C7.1		2788	0.24
chr21_32549988_32550321	0.91	TIAM1	T-cell lymphoma invasion and metastasis 1	47615	0.18
chr14_98606147_98606298	0.91	C14orf64	chromosome 14 open reading frame 64	161761	0.04
chr4_48121703_48121864	0.90	TXK	TXK tyrosine kinase	5221	0.17
chr2_65260459_65260738	0.90	AC007386.4		4033	0.2
chr13_100195644_100195875	0.90	ENSG00000212197	.	7109	0.19
chr14_23031953_23032119	0.90	AE000662.93		6080	0.11
chr2_54185698_54185849	0.88	PSME4	proteasome (prosome, macropain) activator subunit 4	9367	0.19
chr17_40421700_40421882	0.80	RP11-358B23.5		1186	0.3
chr15_64720549_64720703	0.79	TRIP4	thyroid hormone receptor interactor 4	4312	0.13
chrX_123475859_123476089	0.79	SH2D1A	SH2 domain containing 1A	4220	0.35
chr2_120542440_120542591	0.79	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	24715	0.23
chr6_128256239_128256525	0.78	THEMIS	thymocyte selection associated	16606	0.26
chr9_4808660_4808811	0.78	RCL1	RNA terminal phosphate cyclase-like 1	15755	0.16
chr4_154125831_154126000	0.77	TRIM2	tripartite motif containing 2	297	0.93
chr1_154438581_154439022	0.74	RP11-350G8.9		13687	0.12
chr12_112437667_112437849	0.74	TMEM116	transmembrane protein 116	6031	0.17
chr2_69705116_69705317	0.72	ENSG00000244236	.	38667	0.14
chr3_45983815_45984178	0.72	CXCR6	chemokine (C-X-C motif) receptor 6	968	0.5
chr12_22483825_22483976	0.70	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3197	0.37
chr5_61644806_61644957	0.69	KIF2A	kinesin heavy chain member 2A	12252	0.23
chr16_8910898_8911120	0.69	PMM2	phosphomannomutase 2	19285	0.11
chr5_133457481_133458118	0.68	TCF7	transcription factor 7 (T-cell specific, HMG-box)	1510	0.45
chr2_204667394_204667696	0.68	ENSG00000206970	.	20785	0.2
chr20_30884691_30885044	0.67	KIF3B	kinesin family member 3B	13426	0.16
chr18_67600669_67600820	0.67	CD226	CD226 molecule	13911	0.28
chr3_177265737_177265888	0.66	ENSG00000252028	.	44472	0.19
chr17_75958931_75959082	0.66	TNRC6C	trinucleotide repeat containing 6C	41243	0.13
chr13_74860376_74860556	0.66	ENSG00000206617	.	2885	0.39
chr17_33865226_33865568	0.65	SLFN12L	schlafen family member 12-like	517	0.66
chr2_182009261_182009548	0.65	ENSG00000266705	.	160975	0.04
chr14_72917347_72917498	0.65	RGS6	regulator of G-protein signaling 6	3806	0.38
chr16_50816253_50816404	0.64	CYLD	cylindromatosis (turban tumor syndrome)	11200	0.13
chr2_86972550_86972701	0.64	CHMP3	charged multivesicular body protein 3	24380	0.14
chr12_56963842_56964110	0.64	ENSG00000201579	.	18326	0.12
chr3_150923497_150923774	0.63	GPR171	G protein-coupled receptor 171	2647	0.22
chr1_8532692_8532843	0.63	ENSG00000221083	.	39211	0.15
chrX_65280045_65280200	0.63	VSIG4	V-set and immunoglobulin domain containing 4	20155	0.21
chr17_2174008_2174159	0.62	SMG6	SMG6 nonsense mediated mRNA decay factor	4590	0.14
chr3_67702612_67702763	0.62	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	2344	0.46
chr3_119345673_119345833	0.62	PLA1A	phospholipase A1 member A	18009	0.14
chrX_78362545_78362956	0.62	GPR174	G protein-coupled receptor 174	63719	0.15
chr15_44966402_44966553	0.61	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	2271	0.23
chr9_129174532_129174813	0.61	ENSG00000253079	.	3983	0.24
chr17_64668614_64668765	0.61	AC006947.1		3801	0.25
chr17_19670616_19670767	0.61	ALDH3A1	aldehyde dehydrogenase 3 family, member A1	18435	0.14
chr3_142729502_142729745	0.60	U2SURP	U2 snRNP-associated SURP domain containing	8553	0.2
chr13_50680006_50680157	0.60	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	23774	0.17
chr2_231466350_231466527	0.60	ENSG00000199791	.	14602	0.19
chr13_51465573_51465808	0.60	RNASEH2B-AS1	RNASEH2B antisense RNA 1	88	0.97
chrX_48771847_48772324	0.60	PIM2	pim-2 oncogene	927	0.37
chr10_94883671_94883822	0.59	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	50099	0.14
chr17_74141761_74142308	0.59	RNF157-AS1	RNF157 antisense RNA 1	4437	0.13
chrX_19811837_19811988	0.59	SH3KBP1	SH3-domain kinase binding protein 1	5957	0.32
chr5_36168520_36168727	0.59	ENSG00000201223	.	13402	0.13
chr1_169651266_169651443	0.58	SELL	selectin L	29485	0.16
chr1_160591444_160591636	0.58	SLAMF1	signaling lymphocytic activation molecule family member 1	25271	0.13
chr5_56151091_56151462	0.58	ENSG00000238717	.	1699	0.31
chr6_170404456_170404755	0.58	RP11-302L19.1		73136	0.11
chr5_130627404_130627703	0.58	CDC42SE2	CDC42 small effector 2	27760	0.24
chr6_24893270_24893439	0.58	FAM65B	family with sequence similarity 65, member B	15771	0.2
chr20_56990429_56990580	0.57	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	26135	0.2
chr14_65396175_65396395	0.57	CHURC1-FNTB	CHURC1-FNTB readthrough	5531	0.12
chr4_95363524_95363675	0.57	PDLIM5	PDZ and LIM domain 5	9438	0.31
chr14_102295296_102295488	0.56	CTD-2017C7.1		10476	0.15
chr8_124554418_124554701	0.56	FBXO32	F-box protein 32	1113	0.53
chr5_110651912_110652063	0.56	CTC-499J9.1		13722	0.23
chr8_2094139_2094298	0.56	MYOM2	myomesin 2	101034	0.08
chr13_41011930_41012431	0.56	ENSG00000252812	.	30603	0.23
chr11_73705455_73705606	0.56	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11178	0.14
chr8_22385836_22385987	0.55	RP11-582J16.4		17007	0.11
chr5_35855127_35855278	0.55	IL7R	interleukin 7 receptor	1195	0.5
chr9_77692425_77692576	0.54	NMRK1	nicotinamide riboside kinase 1	10606	0.17
chr1_65358491_65358743	0.54	JAK1	Janus kinase 1	73570	0.11
chr2_144282650_144282911	0.54	AC096558.1		44422	0.15
chr15_44969381_44969572	0.54	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	390	0.81
chr13_99892072_99892468	0.54	GPR18	G protein-coupled receptor 18	18358	0.17
chr1_16972090_16972241	0.54	ENSG00000207513	.	21278	0.11
chr17_64394959_64395110	0.54	RP11-4F22.2		16057	0.21
chr1_211511375_211511550	0.53	TRAF5	TNF receptor-associated factor 5	8244	0.25
chr14_64964646_64964818	0.53	ZBTB1	zinc finger and BTB domain containing 1	5711	0.13
chr2_38810640_38810791	0.53	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	13737	0.19
chr10_98342179_98342330	0.53	TM9SF3	transmembrane 9 superfamily member 3	4555	0.23
chr1_100915734_100915885	0.53	RP5-837M10.4		35744	0.16
chr5_118727823_118727974	0.53	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	36168	0.15
chr4_76434239_76434390	0.53	THAP6	THAP domain containing 6	4842	0.22
chr5_39206056_39206207	0.52	FYB	FYN binding protein	3002	0.37
chr4_40230061_40230375	0.52	RHOH	ras homolog family member H	28254	0.18
chr4_71976630_71976836	0.52	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	76270	0.11
chr12_50510545_50510795	0.52	ENSG00000272368	.	4633	0.12
chrX_78055667_78055947	0.52	LPAR4	lysophosphatidic acid receptor 4	52579	0.17
chr15_38848936_38849222	0.52	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	3204	0.24
chr2_44419061_44419212	0.52	PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B	9189	0.18
chr6_130535397_130535548	0.52	SAMD3	sterile alpha motif domain containing 3	963	0.68
chr11_66039967_66040118	0.52	RAB1B	RAB1B, member RAS oncogene family	3981	0.07
chr2_37455195_37455346	0.52	CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	3242	0.16
chr2_204580076_204580351	0.52	CD28	CD28 molecule	8797	0.24
chr7_130591259_130591410	0.52	ENSG00000226380	.	29036	0.21
chr12_4058973_4059124	0.52	RP11-664D1.1		44662	0.18
chr1_22365291_22365442	0.51	CDC42	cell division cycle 42	13754	0.1
chr2_113943965_113944116	0.51	PSD4	pleckstrin and Sec7 domain containing 4	9817	0.14
chr8_38211001_38211152	0.51	RP11-513D5.2		17577	0.12
chr19_40467088_40467239	0.51	PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	9749	0.15
chr2_26017998_26018199	0.51	ASXL2	additional sex combs like 2 (Drosophila)	14920	0.24
chr3_71430025_71430251	0.51	FOXP1	forkhead box P1	76227	0.11
chr2_161333535_161333686	0.51	RBMS1	RNA binding motif, single stranded interacting protein 1	16419	0.25
chr2_225401659_225401810	0.51	CUL3	cullin 3	26282	0.26
chr10_104025435_104025586	0.51	ENSG00000251989	.	4523	0.17
chr6_149812835_149812986	0.51	ZC3H12D	zinc finger CCCH-type containing 12D	6713	0.16
chr14_68675193_68675344	0.50	ENSG00000243546	.	27988	0.2
chr6_146186713_146187159	0.50	SHPRH	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	27554	0.19
chr4_99585641_99585846	0.50	RP11-1299A16.3		5688	0.24
chr16_58211048_58211199	0.50	CSNK2A2	casein kinase 2, alpha prime polypeptide	9506	0.13
chr4_143186380_143186570	0.50	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	40510	0.23
chr6_139611049_139611211	0.50	TXLNB	taxilin beta	2146	0.33
chr14_95947758_95947909	0.50	SYNE3	spectrin repeat containing, nuclear envelope family member 3	5660	0.2
chr1_92015004_92015187	0.49	CDC7	cell division cycle 7	48400	0.18
chr9_6440670_6440821	0.49	RP11-307L3.4		8813	0.19
chr22_47173522_47173673	0.49	TBC1D22A	TBC1 domain family, member 22A	3773	0.23
chr12_21639279_21639430	0.48	RECQL	RecQ protein-like (DNA helicase Q1-like)	15131	0.16
chr12_108692857_108693008	0.48	CMKLR1	chemokine-like receptor 1	18762	0.25
chr14_91849957_91850147	0.48	CCDC88C	coiled-coil domain containing 88C	33638	0.17
chr14_61906909_61907060	0.48	PRKCH	protein kinase C, eta	2292	0.38
chr17_27251111_27251402	0.48	RP11-20B24.5		2037	0.15
chr2_161362741_161362892	0.48	RBMS1	RNA binding motif, single stranded interacting protein 1	12511	0.28
chr14_35280112_35280263	0.48	ENSG00000263691	.	9396	0.19
chr3_136383596_136383747	0.47	ENSG00000251708	.	31681	0.16
chr22_21743153_21743304	0.47	ENSG00000200057	.	252	0.73
chr17_30688328_30688479	0.47	ZNF207	zinc finger protein 207	10476	0.14
chr1_27583939_27584156	0.47	ENSG00000252098	.	1989	0.26
chr17_42117794_42117945	0.47	ENSG00000221044	.	15278	0.09
chr2_99087636_99087787	0.47	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	26298	0.2
chrX_19771101_19771354	0.46	SH3KBP1	SH3-domain kinase binding protein 1	5406	0.33
chrX_10346768_10346919	0.46	ENSG00000222133	.	162104	0.04
chr8_19568830_19568981	0.46	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	28633	0.24
chr2_131134527_131134695	0.46	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	6949	0.16
chr15_81623061_81623212	0.46	RP11-761I4.3		1116	0.5
chr17_65722379_65722530	0.46	NOL11	nucleolar protein 11	4888	0.22
chr9_31337418_31337569	0.46	ENSG00000211510	.	563267	0.0
chr6_26405749_26405900	0.46	BTN3A1	butyrophilin, subfamily 3, member A1	3301	0.13
chr17_4945365_4945516	0.46	SLC52A1	solute carrier family 52 (riboflavin transporter), member 1	6713	0.09
chr3_101296189_101296340	0.46	PCNP	PEST proteolytic signal containing nuclear protein	3224	0.18
chrX_41968841_41969057	0.46	ENSG00000212560	.	29834	0.22
chr12_53008948_53009168	0.45	KRT73	keratin 73	58	0.95
chr1_205779881_205780032	0.45	SLC41A1	solute carrier family 41 (magnesium transporter), member 1	2348	0.26
chr15_91084867_91085018	0.45	CRTC3	CREB regulated transcription coactivator 3	11642	0.19
chr8_12923708_12923859	0.45	ENSG00000206996	.	21924	0.21
chr17_46489763_46490057	0.45	SKAP1	src kinase associated phosphoprotein 1	17642	0.13
chr16_3114789_3114950	0.45	IL32	interleukin 32	429	0.57
chr2_175451291_175451480	0.45	WIPF1	WAS/WASL interacting protein family, member 1	1068	0.49
chrX_153323316_153323857	0.45	ENSG00000211524	.	38146	0.08
chrX_78523828_78523979	0.45	GPR174	G protein-coupled receptor 174	97434	0.08
chrX_117668012_117668163	0.45	ENSG00000206862	.	35391	0.17
chr15_56533346_56533619	0.45	RFX7	regulatory factor X, 7	1982	0.32
chr1_205717833_205717984	0.45	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	1496	0.33
chr15_63836616_63836767	0.45	USP3	ubiquitin specific peptidase 3	133	0.97
chrX_19743614_19743887	0.45	SH3KBP1	SH3-domain kinase binding protein 1	15205	0.29
chr16_71826306_71826508	0.45	AP1G1	adaptor-related protein complex 1, gamma 1 subunit	15790	0.13
chr6_158523047_158523198	0.45	SERAC1	serine active site containing 1	16971	0.18
chr2_225798107_225798258	0.45	DOCK10	dedicator of cytokinesis 10	13600	0.29
chr5_139497996_139498147	0.45	PURA	purine-rich element binding protein A	4363	0.16
chr8_29923511_29923662	0.45	TMEM66	transmembrane protein 66	3879	0.19
chr11_6694893_6695051	0.45	MRPL17	mitochondrial ribosomal protein L17	9575	0.1
chr1_23440938_23441089	0.44	LUZP1	leucine zipper protein 1	5390	0.15
chr1_226899852_226900133	0.44	ITPKB	inositol-trisphosphate 3-kinase B	25167	0.18
chr2_30461198_30461467	0.44	LBH	limb bud and heart development	6286	0.25
chrX_39931454_39931605	0.44	BCOR	BCL6 corepressor	4156	0.36
chr14_89030409_89030576	0.44	ZC3H14	zinc finger CCCH-type containing 14	547	0.73
chr6_118006883_118007034	0.44	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	10293	0.28
chr13_46749592_46749817	0.44	ENSG00000240767	.	5821	0.17
chr1_193509617_193509768	0.44	ENSG00000252241	.	191382	0.03
chr9_86303237_86303482	0.44	RP11-522I20.3		19150	0.17
chr22_40452937_40453088	0.44	TNRC6B	trinucleotide repeat containing 6B	11534	0.19
chrX_42902226_42902377	0.44	MAOA	monoamine oxidase A	613166	0.0
chr2_98505709_98505860	0.44	TMEM131	transmembrane protein 131	17925	0.21
chr1_11343898_11344049	0.44	UBIAD1	UbiA prenyltransferase domain containing 1	9982	0.18
chr14_66306376_66306801	0.43	CTD-2014B16.3	Uncharacterized protein	164653	0.04
chr16_395803_396026	0.43	AXIN1	axin 1	6535	0.11
chr3_141270406_141270561	0.43	RASA2-IT1	RASA2 intronic transcript 1 (non-protein coding)	26508	0.21
chr1_224575605_224575875	0.43	ENSG00000266618	.	10273	0.16
chr11_108099295_108099621	0.43	ENSG00000206967	.	873	0.53
chr8_120595000_120595151	0.43	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	10173	0.27
chr12_110429390_110429777	0.42	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	4446	0.21
chr6_166953790_166954161	0.42	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	1963	0.32
chr19_19671052_19671358	0.42	CILP2	cartilage intermediate layer protein 2	22131	0.1
chr5_121317634_121317860	0.42	SRFBP1	serum response factor binding protein 1	20091	0.24
chr3_105549722_105550016	0.42	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	38018	0.24
chr2_175360106_175360322	0.42	GPR155	G protein-coupled receptor 155	8392	0.2
chr6_37494299_37494451	0.42	CCDC167	coiled-coil domain containing 167	26677	0.17
chr22_40500930_40501081	0.42	TNRC6B	trinucleotide repeat containing 6B	59527	0.11
chr14_22939193_22939344	0.42	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	6028	0.11
chr7_150263302_150263625	0.42	GIMAP4	GTPase, IMAP family member 4	902	0.6
chr14_23491861_23492012	0.42	ENSG00000252114	.	5346	0.08
chr13_52542256_52542407	0.42	ATP7B	ATPase, Cu++ transporting, beta polypeptide	6280	0.22
chr1_247580137_247580422	0.42	NLRP3	NLR family, pyrin domain containing 3	821	0.6
chr19_31776817_31777126	0.41	AC007796.1		62816	0.13
chr16_3851146_3851403	0.41	CREBBP	CREB binding protein	20406	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DMC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.4	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.4	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.4	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.3	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	0.7	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.4	GO:0002921	negative regulation of humoral immune response(GO:0002921)
0.1	0.5	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.2	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.2	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.1	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.3	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.3	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.1	0.1	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.2	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.1	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.4	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.3	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.2	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.2	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.2	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0072191	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.4	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.3	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.4	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.2	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.7	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.2	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.4	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.3	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.1	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.0	0.1	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.1	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.2	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.2	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.6	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.2	GO:0075733	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0032095	regulation of response to food(GO:0032095)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.2	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.8	GO:1902403	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.3	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0045911	positive regulation of isotype switching(GO:0045830) positive regulation of DNA recombination(GO:0045911)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.2	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:2000040	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.0	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.1	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.1	GO:0021610	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.0	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.3	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0060453	regulation of gastric acid secretion(GO:0060453) uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.0	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.3	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.0	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.3	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005827	polar microtubule(GO:0005827)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.4	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.4	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0043209	myelin sheath(GO:0043209)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	1.4	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0030175	filopodium(GO:0030175)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.6	GO:0000786	nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.3	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.3	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.1	0.2	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.0	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.5	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.3	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.3	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.6	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.0	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.2	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	0.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	1.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.2	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.1	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.1	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.5	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21

Results for DMC1

Z-value: 2.12

Motif logo

Transcription factors associated with DMC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the DMC1 motif across conditions

Conditions sorted by the z-value of the DMC1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DMC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: