Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for DPRX

Z-value: 1.92

Motif logo

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Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
ENSG00000204595.1 divergent-paired related homeobox

Activity of the DPRX motif across conditions

Conditions sorted by the z-value of the DPRX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_121906222_121906519 0.68 ENSG00000252556
.
31307
0.16
chr17_47900739_47901025 0.63 RP11-304F15.3

22390
0.13
chr12_4140465_4141124 0.56 RP11-664D1.1

126408
0.05
chr1_100789092_100789243 0.54 CDC14A
cell division cycle 14A
21417
0.15
chr5_102310797_102310948 0.54 PAM
peptidylglycine alpha-amidating monooxygenase
25591
0.26
chr2_145266955_145267602 0.52 ZEB2
zinc finger E-box binding homeobox 2
7837
0.25
chr1_56185258_56185409 0.50 PIGQP1
phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
219620
0.02
chr7_107331221_107331712 0.50 SLC26A4
solute carrier family 26 (anion exchanger), member 4
869
0.57
chr15_101807298_101807582 0.50 VIMP
VCP-interacting membrane protein
10052
0.15
chr10_79267255_79267533 0.50 ENSG00000199592
.
79413
0.1
chr19_10529958_10530965 0.49 CDC37
cell division cycle 37
336
0.7
chr16_640639_641593 0.49 RAB40C
RAB40C, member RAS oncogene family
784
0.37
chr22_44759775_44760116 0.48 RP1-32I10.10
Uncharacterized protein
1486
0.51
chr15_43806030_43806788 0.46 MAP1A
microtubule-associated protein 1A
3253
0.18
chr3_193988294_193988600 0.46 CPN2
carboxypeptidase N, polypeptide 2
83600
0.08
chr12_94312317_94312468 0.46 RP11-1060G2.1

24987
0.2
chr1_110923779_110923930 0.45 LAMTOR5-AS1
LAMTOR5 antisense RNA 1
1587
0.24
chr16_66150653_66150937 0.45 ENSG00000201999
.
184917
0.03
chr8_25771009_25771433 0.45 EBF2
early B-cell factor 2
25789
0.27
chr6_45619110_45619261 0.45 ENSG00000252738
.
5344
0.34
chr14_69015321_69015580 0.45 CTD-2325P2.4

79712
0.1
chr19_41035362_41036035 0.44 SPTBN4
spectrin, beta, non-erythrocytic 4
697
0.62
chr1_219761600_219761751 0.44 ENSG00000252240
.
75044
0.12
chr9_111202576_111202727 0.44 ENSG00000222512
.
81442
0.11
chr4_148693217_148693552 0.43 ENSG00000264274
.
10362
0.18
chr5_143022321_143022472 0.43 ENSG00000266478
.
37029
0.18
chr11_131626567_131626718 0.43 NTM
neurotrimin
95754
0.08
chr1_146736722_146736873 0.43 CHD1L
chromodomain helicase DNA binding protein 1-like
22441
0.19
chr21_36625750_36625901 0.43 RUNX1
runt-related transcription factor 1
204184
0.03
chr17_57502582_57502794 0.43 RP11-567L7.5

22024
0.18
chr5_118728587_118729031 0.43 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
37079
0.14
chr6_143169141_143169292 0.42 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
11032
0.28
chr12_110388287_110388838 0.42 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
45467
0.11
chr1_203147074_203147225 0.42 MYBPH
myosin binding protein H
2208
0.22
chr1_120485813_120485964 0.41 RP5-1042I8.7

32652
0.18
chr9_94579747_94580327 0.41 ROR2
receptor tyrosine kinase-like orphan receptor 2
131125
0.05
chr3_197238562_197238713 0.41 BDH1
3-hydroxybutyrate dehydrogenase, type 1
2629
0.37
chr10_44973931_44974082 0.41 CXCL12
chemokine (C-X-C motif) ligand 12
93466
0.08
chr16_87120298_87120449 0.41 RP11-899L11.3

129148
0.05
chr1_153521085_153521570 0.41 S100A3
S100 calcium binding protein A3
275
0.76
chr3_159740833_159741097 0.40 LINC01100
long intergenic non-protein coding RNA 1100
7154
0.2
chr4_72061466_72061617 0.40 SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
8497
0.31
chr17_41487227_41487378 0.40 ENSG00000251763
.
2493
0.17
chr2_46196026_46196177 0.39 PRKCE
protein kinase C, epsilon
31940
0.23
chr7_132423668_132423819 0.39 ENSG00000201009
.
14040
0.21
chr3_123836876_123837056 0.39 ENSG00000266383
.
14810
0.2
chr12_76636613_76636764 0.39 ENSG00000223273
.
72843
0.1
chr8_98910268_98910419 0.39 MATN2
matrilin 2
10138
0.24
chr1_120508182_120508333 0.39 RP5-1042I8.7

55021
0.13
chr9_88955484_88955635 0.39 ZCCHC6
zinc finger, CCHC domain containing 6
2479
0.34
chr4_77657284_77657435 0.39 RP11-359D14.2

22268
0.2
chr2_191910102_191910403 0.39 ENSG00000231858
.
24000
0.15
chr17_59383316_59383467 0.38 RP11-332H18.3

76755
0.08
chr3_100730226_100730377 0.38 ABI3BP
ABI family, member 3 (NESH) binding protein
17942
0.25
chr11_75338227_75338378 0.38 CTD-2530H12.7

11330
0.14
chr6_131221994_131222145 0.38 EPB41L2
erythrocyte membrane protein band 4.1-like 2
10505
0.29
chr2_63991472_63991650 0.38 ENSG00000221085
.
68892
0.11
chr5_158232307_158232458 0.38 CTD-2363C16.1

177632
0.03
chr3_16225459_16225610 0.37 GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
9318
0.25
chr1_219512383_219512534 0.37 RP11-135J2.4

165155
0.04
chr7_111079181_111079332 0.37 IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
46285
0.2
chr21_28335085_28335236 0.37 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
3672
0.27
chr13_21653666_21653823 0.37 LATS2
large tumor suppressor kinase 2
18058
0.14
chr2_237654687_237654838 0.37 ACKR3
atypical chemokine receptor 3
176478
0.03
chr2_37797708_37797859 0.37 AC006369.2

29496
0.21
chr11_130717130_130717402 0.36 SNX19
sorting nexin 19
46503
0.19
chrX_19655066_19655217 0.36 SH3KBP1
SH3-domain kinase binding protein 1
33339
0.23
chr8_108344894_108345045 0.36 ANGPT1
angiopoietin 1
3781
0.36
chr11_26798911_26799062 0.36 SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
54078
0.17
chr14_58313511_58313662 0.36 ENSG00000252837
.
9208
0.24
chr3_79211716_79211867 0.36 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
143182
0.05
chr3_120150563_120150714 0.36 FSTL1
follistatin-like 1
19200
0.23
chr2_55346845_55347305 0.36 RTN4
reticulon 4
7318
0.2
chr12_43684777_43685026 0.36 ENSG00000215993
.
482
0.89
chr5_39474112_39474263 0.36 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
11785
0.3
chr11_101312154_101312305 0.35 ENSG00000263885
.
78407
0.11
chr17_61434785_61434936 0.35 AC037445.1

18446
0.15
chr16_70748567_70748858 0.35 VAC14
Vac14 homolog (S. cerevisiae)
14564
0.14
chr3_61557704_61557855 0.35 PTPRG
protein tyrosine phosphatase, receptor type, G
10194
0.32
chr14_63983384_63983535 0.35 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
8504
0.16
chr2_200235271_200235422 0.35 RP11-486F17.1

45313
0.17
chr11_78029619_78030164 0.35 RP11-452H21.1

5913
0.21
chr15_75757189_75757340 0.34 SIN3A
SIN3 transcription regulator family member A
9081
0.18
chr5_169029408_169029559 0.34 SPDL1
spindle apparatus coiled-coil protein 1
11375
0.22
chr8_53030633_53030784 0.34 RP11-26M5.3

32672
0.21
chr3_179519553_179519750 0.34 PEX5L-AS1
PEX5L antisense RNA 1
73513
0.09
chr1_178358349_178358628 0.34 RASAL2
RAS protein activator like 2
47882
0.16
chr7_25891719_25892347 0.34 ENSG00000199085
.
97573
0.09
chr12_15843418_15843825 0.34 ENSG00000200105
.
18877
0.22
chr18_18585315_18585510 0.34 ROCK1
Rho-associated, coiled-coil containing protein kinase 1
50581
0.15
chr3_73510661_73510812 0.34 PDZRN3
PDZ domain containing ring finger 3
13047
0.29
chr12_22066370_22066521 0.34 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
2533
0.37
chr2_189540912_189541063 0.34 GULP1
GULP, engulfment adaptor PTB domain containing 1
106177
0.07
chr7_48222386_48222537 0.34 ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
11404
0.28
chr15_71335826_71335977 0.34 THSD4
thrombospondin, type I, domain containing 4
53390
0.14
chr10_129721465_129721616 0.34 RP11-4C20.4

11422
0.21
chr1_86953450_86953601 0.34 CLCA1
chloride channel accessory 1
18999
0.2
chr3_139028342_139028493 0.34 MRPS22
mitochondrial ribosomal protein S22
34444
0.14
chr8_98001138_98001426 0.34 CPQ
carboxypeptidase Q
40415
0.21
chr19_1361317_1362052 0.33 MUM1
melanoma associated antigen (mutated) 1
5321
0.1
chr6_113468632_113468783 0.33 ENSG00000201386
.
176012
0.03
chr11_128685529_128685949 0.33 KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
26690
0.17
chr2_68351761_68351912 0.33 WDR92
WD repeat domain 92
14081
0.18
chr7_20204502_20204823 0.33 MACC1
metastasis associated in colon cancer 1
20039
0.18
chr3_38870449_38870600 0.33 RP11-134J21.1

5131
0.21
chr8_72778454_72778605 0.33 MSC
musculin
21826
0.17
chr8_9305826_9305977 0.33 ENSG00000201815
.
77196
0.1
chr11_72868697_72869453 0.33 FCHSD2
FCH and double SH3 domains 2
15769
0.19
chr10_96075798_96075949 0.33 RP11-76P2.4

789
0.65
chr5_119879644_119879795 0.33 PRR16
proline rich 16
12560
0.31
chr14_75295916_75296067 0.33 YLPM1
YLP motif containing 1
12050
0.14
chr6_52406315_52406466 0.33 TRAM2
translocation associated membrane protein 2
35323
0.19
chr10_114819664_114819822 0.33 TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
83936
0.1
chr7_27498955_27499106 0.33 HIBADH
3-hydroxyisobutyrate dehydrogenase
188345
0.02
chr11_73578174_73578325 0.33 COA4
cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
7271
0.15
chr14_75085505_75086322 0.33 LTBP2
latent transforming growth factor beta binding protein 2
6607
0.2
chr2_121583330_121583481 0.33 GLI2
GLI family zinc finger 2
28484
0.25
chr7_44923182_44923985 0.33 RP4-673M15.1

969
0.35
chr5_169289355_169289506 0.32 CTB-37A13.1

83061
0.09
chr5_151052659_151052857 0.32 CTB-113P19.1

3748
0.18
chr1_236146948_236147099 0.32 ENSG00000206803
.
68308
0.09
chr12_108292570_108292721 0.32 ENSG00000263632
.
99148
0.07
chr6_132259402_132259553 0.32 RP11-69I8.3

12609
0.21
chr5_82670520_82670671 0.32 VCAN
versican
96689
0.09
chr2_45346900_45347051 0.32 SIX2
SIX homeobox 2
110406
0.07
chr18_43309151_43309302 0.32 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
232
0.93
chr5_34487773_34488055 0.32 RAI14
retinoic acid induced 14
168428
0.03
chr3_174978584_174978880 0.32 NAALADL2-AS2
NAALADL2 antisense RNA 2
10153
0.29
chr20_44548690_44548841 0.32 PLTP
phospholipid transfer protein
7971
0.09
chr5_64500241_64500433 0.32 ENSG00000207439
.
81141
0.11
chr9_16706324_16706475 0.32 BNC2
basonuclin 2
1319
0.52
chr3_134079354_134079505 0.32 AMOTL2
angiomotin like 2
11325
0.22
chr18_400089_400498 0.32 RP11-720L2.2

24123
0.21
chr2_53803598_53803749 0.32 ENSG00000207456
.
6056
0.28
chr2_37699858_37700009 0.32 ENSG00000253078
.
37182
0.18
chr8_22860932_22861110 0.32 PEBP4
phosphatidylethanolamine-binding protein 4
3508
0.15
chr9_113606609_113606760 0.32 ENSG00000206923
.
58933
0.13
chr22_36727795_36728637 0.32 ENSG00000266345
.
15970
0.18
chr1_36173339_36173885 0.32 ENSG00000239859
.
1737
0.31
chr5_9523779_9523930 0.32 CTD-2201E9.2

564
0.77
chr12_58759641_58759792 0.32 RP11-362K2.2
Protein LOC100506869
178191
0.03
chr12_2357520_2357671 0.32 CACNA1C-IT3
CACNA1C intronic transcript 3 (non-protein coding)
21347
0.21
chr18_43308457_43308608 0.32 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
462
0.82
chr4_77532872_77533023 0.32 AC107072.2

25829
0.15
chr5_111165116_111165267 0.31 NREP
neuronal regeneration related protein
71276
0.1
chr7_107284240_107284391 0.31 SLC26A4
solute carrier family 26 (anion exchanger), member 4
16765
0.14
chr13_32340647_32340798 0.31 RXFP2
relaxin/insulin-like family peptide receptor 2
27043
0.26
chr13_43579931_43580082 0.31 EPSTI1
epithelial stromal interaction 1 (breast)
13621
0.24
chr18_447628_447904 0.31 RP11-720L2.2

23350
0.19
chr15_70615447_70615598 0.31 ENSG00000200216
.
129947
0.06
chr18_74789491_74789956 0.31 MBP
myelin basic protein
27494
0.24
chr22_30440835_30440986 0.31 HORMAD2
HORMA domain containing 2
35253
0.13
chr5_64493902_64494516 0.31 ENSG00000207439
.
75013
0.12
chr3_123378808_123378959 0.31 MYLK-AS2
MYLK antisense RNA 2
29608
0.15
chr4_17069080_17069231 0.31 LDB2
LIM domain binding 2
168723
0.04
chr11_125984167_125984417 0.31 CDON
cell adhesion associated, oncogene regulated
51062
0.1
chr20_37602831_37602982 0.31 DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
11919
0.19
chr5_58460603_58460754 0.31 PDE4D
phosphodiesterase 4D, cAMP-specific
111267
0.07
chr15_70779488_70780159 0.31 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
214797
0.02
chr1_203167082_203167289 0.31 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
11308
0.14
chr9_82231282_82231433 0.31 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
36151
0.25
chr13_77304738_77304889 0.31 KCTD12
potassium channel tetramerization domain containing 12
155712
0.04
chr20_16904101_16904252 0.31 ENSG00000212165
.
59502
0.15
chr4_151151399_151151550 0.31 ENSG00000238721
.
20616
0.25
chr1_101200153_101200304 0.30 VCAM1
vascular cell adhesion molecule 1
14908
0.26
chr13_24561197_24561348 0.30 SPATA13
spermatogenesis associated 13
7328
0.23
chr12_49206263_49206414 0.30 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
1896
0.18
chr1_97024047_97024198 0.30 ENSG00000241992
.
24643
0.26
chr10_63223643_63223794 0.30 TMEM26
transmembrane protein 26
10510
0.24
chr12_26304780_26304931 0.30 SSPN
sarcospan
16955
0.18
chr4_187544517_187544858 0.30 FAT1
FAT atypical cadherin 1
25509
0.2
chr5_137566220_137566371 0.30 CDC23
cell division cycle 23
17263
0.12
chr8_110414330_110414481 0.30 PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
39699
0.16
chr17_71285096_71285247 0.30 CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
22376
0.14
chr6_1614767_1615035 0.30 FOXC1
forkhead box C1
4220
0.35
chr6_52383740_52383891 0.30 TRAM2
translocation associated membrane protein 2
57898
0.13
chr5_125473495_125473784 0.30 ENSG00000265637
.
58889
0.16
chr10_128569188_128569339 0.30 DOCK1
dedicator of cytokinesis 1
24715
0.21
chr4_48390789_48390940 0.30 SLAIN2
SLAIN motif family, member 2
5169
0.28
chr5_36300674_36300825 0.30 RANBP3L
RAN binding protein 3-like
1253
0.53
chr8_105352335_105352486 0.30 DCSTAMP
dendrocyte expressed seven transmembrane protein
356
0.9
chr3_114136877_114137028 0.30 ZBTB20-AS1
ZBTB20 antisense RNA 1
30436
0.18
chr5_34489512_34489663 0.30 RAI14
retinoic acid induced 14
166755
0.03
chr17_2082426_2082658 0.30 SMG6
SMG6 nonsense mediated mRNA decay factor
6070
0.13
chr15_57436408_57436559 0.30 TCF12
transcription factor 12
75145
0.11
chr11_70261652_70262194 0.30 CTTN
cortactin
4308
0.17
chr5_121417331_121417482 0.29 LOX
lysyl oxidase
3426
0.28
chr4_144318381_144318532 0.29 GAB1
GRB2-associated binding protein 1
5793
0.26
chr20_18685450_18685672 0.29 RP11-379J5.5

6208
0.24
chr12_49653469_49653759 0.29 RP11-977B10.2

4925
0.12
chr2_121695887_121696038 0.29 ENSG00000221321
.
96687
0.08
chr18_53869860_53870011 0.29 ENSG00000201816
.
123110
0.06
chr7_51030538_51030756 0.29 ENSG00000201133
.
27457
0.23
chr12_64773878_64774029 0.29 C12orf56
chromosome 12 open reading frame 56
10353
0.17
chr12_63253482_63253831 0.29 ENSG00000200296
.
8975
0.26
chr15_49966362_49966513 0.29 RP11-353B9.1

22101
0.2
chr9_113506622_113506773 0.29 MUSK
muscle, skeletal, receptor tyrosine kinase
30930
0.23
chr10_22542450_22542989 0.29 EBLN1
endogenous Bornavirus-like nucleoprotein 1
43769
0.13
chr9_4838397_4838548 0.29 RCL1
RNA terminal phosphate cyclase-like 1
1046
0.47
chr8_12978290_12978441 0.29 DLC1
deleted in liver cancer 1
4612
0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.3 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.4 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.4 GO:0015840 urea transport(GO:0015840)
0.1 0.3 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.3 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.1 GO:0072191 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.1 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0061043 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.2 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:2000846 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.2 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.3 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0060592 mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.0 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807) urinary bladder development(GO:0060157)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0072243 metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0009130 UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.2 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0071450 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.0 GO:0030016 myofibril(GO:0030016)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0042805 actinin binding(GO:0042805)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP