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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for DUXA

Z-value: 2.02

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Transcription factors associated with DUXA

Gene Symbol	Gene ID	Gene Info
DUXA Ensembl NCBI GeneCards UniProt	ENSG00000258873.2	double homeobox A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_57684375_57684526	DUXA	5639	0.134940	0.43	2.5e-01	Click!
chr19_57683108_57683259	DUXA	4372	0.145072	-0.40	2.8e-01	Click!
chr19_57683696_57683946	DUXA	5010	0.139117	-0.39	3.0e-01	Click!
chr19_57682896_57683091	DUXA	4182	0.147338	0.07	8.6e-01	Click!

Activity of the DUXA motif across conditions

Conditions sorted by the z-value of the DUXA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_113944634_113944785	0.78	RP11-553L6.2		11471	0.16
chr2_158276348_158276584	0.76	CYTIP	cytohesin 1 interacting protein	19460	0.2
chr6_41048012_41048396	0.73	NFYA	nuclear transcription factor Y, alpha	7482	0.13
chr2_204862423_204862574	0.67	ICOS	inducible T-cell co-stimulator	60995	0.15
chr1_31528980_31529131	0.66	PUM1	pumilio RNA-binding family member 1	5708	0.25
chrX_135818033_135818184	0.63	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	31394	0.15
chr1_93421926_93422077	0.61	FAM69A	family with sequence similarity 69, member A	5056	0.14
chr8_64111688_64111878	0.61	YTHDF3	YTH domain family, member 3	11695	0.24
chr14_21697616_21697899	0.59	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	1824	0.32
chr10_5751764_5752007	0.58	RP11-336A10.2		4501	0.2
chrX_147391495_147391734	0.56	AC002368.4		190521	0.03
chr22_23132033_23132342	0.56	ENSG00000207833	.	2790	0.07
chr4_129744326_129744477	0.55	JADE1	jade family PHD finger 1	8187	0.3
chr6_149698924_149699075	0.55	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	7955	0.2
chr5_141506960_141507157	0.54	NDFIP1	Nedd4 family interacting protein 1	18988	0.23
chr1_121293995_121294146	0.54	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	358133	0.01
chr16_53492869_53493169	0.53	RBL2	retinoblastoma-like 2 (p130)	9031	0.16
chr2_190169458_190169686	0.53	ENSG00000266817	.	6915	0.29
chr2_28990698_28991000	0.52	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	11017	0.17
chr14_39459025_39459176	0.52	ENSG00000199285	.	2615	0.38
chr1_29289116_29289267	0.51	ENSG00000206704	.	23031	0.18
chr1_118174606_118174870	0.50	FAM46C	family with sequence similarity 46, member C	26182	0.18
chr2_204725673_204726054	0.49	CTLA4	cytotoxic T-lymphocyte-associated protein 4	6646	0.27
chr4_90194238_90194389	0.48	GPRIN3	GPRIN family member 3	21968	0.26
chr2_64766558_64766735	0.48	AFTPH	aftiphilin	11963	0.21
chr9_20315636_20315970	0.48	ENSG00000221744	.	20801	0.22
chr5_66500186_66500434	0.48	CD180	CD180 molecule	7683	0.3
chr22_45570848_45571064	0.48	CTA-268H5.12		3915	0.19
chr10_11280877_11281143	0.48	RP3-323N1.2		67671	0.11
chr10_33315822_33316332	0.47	ENSG00000265319	.	7775	0.23
chr5_55909103_55909387	0.47	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	7186	0.27
chr6_37475943_37476266	0.46	CCDC167	coiled-coil domain containing 167	8406	0.21
chr4_36238228_36238379	0.46	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	7258	0.22
chr14_35399368_35399560	0.46	ENSG00000199980	.	3285	0.23
chr1_234511758_234511909	0.46	COA6	cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)	2386	0.2
chr15_60841099_60841376	0.46	CTD-2501E16.2		19065	0.18
chr7_36978892_36979043	0.46	ENSG00000221325	.	19930	0.2
chr2_175355289_175355522	0.46	GPR155	G protein-coupled receptor 155	3583	0.24
chr12_92434816_92435054	0.45	C12orf79	chromosome 12 open reading frame 79	95862	0.08
chr15_66180485_66180674	0.45	RAB11A	RAB11A, member RAS oncogene family	18228	0.19
chr6_52151332_52151486	0.45	MCM3	minichromosome maintenance complex component 3	1774	0.39
chr2_225897343_225897494	0.45	DOCK10	dedicator of cytokinesis 10	9741	0.26
chr3_196085184_196085335	0.45	ENSG00000212146	.	16673	0.1
chr13_42041149_42041395	0.44	RGCC	regulator of cell cycle	9577	0.16
chr14_98169584_98169886	0.44	RP11-204N11.1	Uncharacterized protein	59433	0.16
chr1_161034126_161034311	0.44	AL591806.1	Uncharacterized protein	1437	0.2
chr1_207633377_207633528	0.44	CR2	complement component (3d/Epstein Barr virus) receptor 2	5742	0.23
chrX_15779492_15779655	0.43	CA5B	carbonic anhydrase VB, mitochondrial	11480	0.18
chr3_16962750_16962901	0.43	PLCL2	phospholipase C-like 2	11757	0.23
chr4_90213174_90213336	0.43	GPRIN3	GPRIN family member 3	15906	0.29
chr2_196429892_196430125	0.42	SLC39A10	solute carrier family 39 (zinc transporter), member 10	10693	0.26
chr1_101746005_101746240	0.42	RP4-575N6.5		37408	0.14
chrX_70275286_70275454	0.42	SNX12	sorting nexin 12	12883	0.13
chr21_47951540_47951799	0.42	ENSG00000272283	.	4040	0.2
chr22_40305396_40305614	0.41	GRAP2	GRB2-related adaptor protein 2	8392	0.18
chr3_3210621_3210772	0.41	CRBN	cereblon	10662	0.18
chr11_121320555_121321108	0.41	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	2081	0.35
chr12_40077357_40077585	0.41	C12orf40	chromosome 12 open reading frame 40	57486	0.13
chr11_73723870_73724108	0.41	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	3509	0.2
chr2_143904763_143905163	0.41	ARHGAP15	Rho GTPase activating protein 15	18080	0.23
chr2_148056205_148056470	0.41	ENSG00000238860	.	25202	0.25
chr9_74372093_74372294	0.41	TMEM2	transmembrane protein 2	11109	0.29
chr1_110344325_110344822	0.41	EPS8L3	EPS8-like 3	37924	0.11
chr10_32749900_32750051	0.40	CCDC7	coiled-coil domain containing 7	9426	0.22
chr12_92425801_92426181	0.40	C12orf79	chromosome 12 open reading frame 79	104806	0.07
chr6_35623383_35623638	0.40	ENSG00000212579	.	3915	0.18
chr4_96076478_96076629	0.40	BMPR1B	bone morphogenetic protein receptor, type IB	51047	0.19
chr6_11713814_11713965	0.40	ENSG00000207419	.	3837	0.29
chr6_16437826_16437977	0.40	ENSG00000265642	.	9147	0.31
chr3_43205466_43205617	0.40	ENSG00000222331	.	46822	0.14
chr8_121714189_121714356	0.40	RP11-713M15.1		59221	0.14
chr2_85074501_85074773	0.40	TRABD2A	TraB domain containing 2A	33569	0.16
chr6_86377925_86378076	0.40	ENSG00000203875	.	9086	0.19
chr6_108111459_108111610	0.40	SCML4	sex comb on midleg-like 4 (Drosophila)	18079	0.26
chr1_158966768_158966929	0.40	IFI16	interferon, gamma-inducible protein 16	2910	0.28
chr7_55538938_55539284	0.40	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	44659	0.17
chr6_112091641_112091792	0.40	FYN	FYN oncogene related to SRC, FGR, YES	10567	0.27
chr8_129566610_129566901	0.40	ENSG00000221351	.	265285	0.02
chr14_99726122_99726406	0.39	AL109767.1		3021	0.29
chr6_53209551_53209971	0.39	ELOVL5	ELOVL fatty acid elongase 5	3826	0.26
chr10_7825346_7825497	0.39	KIN	KIN, antigenic determinant of recA protein homolog (mouse)	4523	0.21
chr2_233636940_233637117	0.39	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13	913	0.49
chr6_135342025_135342194	0.39	HBS1L	HBS1-like (S. cerevisiae)	6185	0.23
chr4_109029927_109030290	0.39	LEF1	lymphoid enhancer-binding factor 1	57349	0.12
chr7_50462451_50462702	0.39	ENSG00000200815	.	40502	0.17
chr8_29357532_29357791	0.39	RP4-676L2.1		146974	0.04
chr10_11243448_11243865	0.39	RP3-323N1.2		30317	0.19
chr2_198052589_198052979	0.39	ANKRD44	ankyrin repeat domain 44	951	0.61
chr15_87154712_87154913	0.38	RP11-182L7.1		19555	0.29
chr14_98691862_98692070	0.38	ENSG00000222066	.	106121	0.08
chr14_92472005_92472156	0.38	TRIP11	thyroid hormone receptor interactor 11	10015	0.19
chr12_9104317_9104548	0.38	KLRG1	killer cell lectin-like receptor subfamily G, member 1	1792	0.26
chr10_63792763_63793061	0.38	ARID5B	AT rich interactive domain 5B (MRF1-like)	16058	0.26
chr20_1344489_1344952	0.38	RP11-314N13.3		2454	0.22
chr7_7963022_7963173	0.38	ENSG00000201747	.	16947	0.18
chr2_158305057_158305360	0.38	CYTIP	cytohesin 1 interacting protein	4554	0.25
chr7_139953768_139953977	0.38	ENSG00000199283	.	12202	0.18
chr6_83788864_83789015	0.38	AL139333.1		6247	0.2
chr12_92423272_92423557	0.38	C12orf79	chromosome 12 open reading frame 79	107383	0.07
chr1_192485085_192485271	0.38	ENSG00000221145	.	24828	0.2
chrX_73169320_73169471	0.38	RP13-216E22.5		19925	0.24
chr17_37976521_37976672	0.38	IKZF3	IKAROS family zinc finger 3 (Aiolos)	42118	0.1
chr6_112181402_112181564	0.38	FYN	FYN oncogene related to SRC, FGR, YES	1897	0.47
chr13_52527464_52527703	0.38	ATP7B	ATPase, Cu++ transporting, beta polypeptide	8468	0.22
chr10_6619083_6619311	0.38	PRKCQ	protein kinase C, theta	3004	0.4
chr2_37844722_37844873	0.38	AC006369.2		17518	0.22
chr12_14958656_14958876	0.38	C12orf60	chromosome 12 open reading frame 60	2260	0.17
chr5_79519389_79519540	0.37	ENSG00000239159	.	15944	0.19
chr18_5058444_5058595	0.37	ENSG00000222463	.	70351	0.13
chr10_1037189_1037340	0.37	GTPBP4	GTP binding protein 4	2609	0.18
chr6_37878002_37878153	0.37	ENSG00000200597	.	5272	0.24
chr10_17110085_17110236	0.37	CUBN	cubilin (intrinsic factor-cobalamin receptor)	59676	0.13
chr2_205832841_205832992	0.37	PARD3B	par-3 family cell polarity regulator beta	422193	0.01
chr3_186724517_186724802	0.37	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	14984	0.23
chr6_152503881_152504032	0.37	SYNE1	spectrin repeat containing, nuclear envelope 1	14457	0.29
chr3_20086193_20086461	0.37	KAT2B	K(lysine) acetyltransferase 2B	4812	0.22
chr5_78536587_78536823	0.37	JMY	junction mediating and regulatory protein, p53 cofactor	4693	0.2
chr10_63944898_63945096	0.37	RTKN2	rhotekin 2	51025	0.15
chr10_35808142_35808293	0.37	GJD4	gap junction protein, delta 4, 40.1kDa	86121	0.08
chr5_142602836_142603470	0.37	ARHGAP26	Rho GTPase activating protein 26	16388	0.24
chr17_33840627_33840778	0.37	RP11-1094M14.5		3413	0.16
chr5_156674809_156675091	0.37	ENSG00000222086	.	12641	0.13
chr7_50301242_50301499	0.37	IKZF1	IKAROS family zinc finger 1 (Ikaros)	42954	0.18
chr5_56127051_56127301	0.36	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	15775	0.16
chr17_1776335_1776696	0.36	RPA1	replication protein A1, 70kDa	5814	0.17
chrX_42259008_42259366	0.36	ENSG00000206896	.	225549	0.02
chr2_136415073_136415292	0.36	ENSG00000201308	.	1033	0.52
chr1_151869049_151869200	0.36	THEM4	thioesterase superfamily member 4	12989	0.12
chr17_14106793_14106965	0.36	AC005224.2		6926	0.21
chr1_22391682_22391833	0.36	CDC42-IT1	CDC42 intronic transcript 1 (non-protein coding)	6067	0.14
chr2_197019452_197019652	0.36	STK17B	serine/threonine kinase 17b	1819	0.35
chrX_44106060_44106211	0.36	EFHC2	EF-hand domain (C-terminal) containing 2	96783	0.09
chr22_40926921_40927072	0.36	MKL1	megakaryoblastic leukemia (translocation) 1	2819	0.22
chr10_4170376_4170710	0.36	KLF6	Kruppel-like factor 6	343070	0.01
chr7_130776999_130777212	0.36	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	3872	0.25
chr14_32414488_32414678	0.36	RP11-187E13.1	Uncharacterized protein	524	0.84
chr15_64918455_64918632	0.36	ENSG00000207223	.	26544	0.13
chr3_108547242_108547393	0.36	TRAT1	T cell receptor associated transmembrane adaptor 1	5698	0.28
chr21_17196280_17196536	0.36	USP25	ubiquitin specific peptidase 25	921	0.72
chr15_77307770_77308045	0.36	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	245	0.93
chr7_114605623_114605774	0.36	MDFIC	MyoD family inhibitor domain containing	31774	0.25
chr17_1774569_1774930	0.36	RPA1	replication protein A1, 70kDa	7580	0.16
chr12_92430014_92430197	0.36	C12orf79	chromosome 12 open reading frame 79	100692	0.07
chr5_55276808_55277096	0.36	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	1676	0.31
chr14_98871416_98871598	0.36	ENSG00000241757	.	53506	0.16
chr6_36077167_36077664	0.35	MAPK13	mitogen-activated protein kinase 13	20683	0.16
chr5_112359579_112359730	0.35	DCP2	decapping mRNA 2	47175	0.15
chr11_48032636_48032854	0.35	AC103828.1		4662	0.24
chr2_64447296_64447534	0.35	AC074289.1		7580	0.28
chr1_90107000_90107373	0.35	LRRC8C	leucine rich repeat containing 8 family, member C	8555	0.17
chr4_40211579_40212128	0.35	RHOH	ras homolog family member H	9889	0.22
chr2_190655528_190655679	0.35	PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	823	0.49
chr9_134546803_134547477	0.35	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	38089	0.16
chr12_62998741_62998934	0.35	ENSG00000199179	.	1371	0.28
chr2_43402387_43402951	0.35	ZFP36L2	ZFP36 ring finger protein-like 2	51079	0.14
chr9_88953538_88953925	0.35	ZCCHC6	zinc finger, CCHC domain containing 6	4307	0.27
chr3_138479937_138480088	0.35	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	1827	0.47
chr16_53579848_53579999	0.35	AKTIP	AKT interacting protein	41600	0.16
chr20_31323744_31323998	0.35	COMMD7	COMM domain containing 7	7341	0.2
chr8_126935069_126935250	0.35	ENSG00000206695	.	21964	0.28
chr5_55301933_55302084	0.35	ENSG00000238326	.	5559	0.17
chr17_37925720_37925871	0.35	IKZF3	IKAROS family zinc finger 3 (Aiolos)	8683	0.13
chr10_116299670_116299821	0.35	ABLIM1	actin binding LIM protein 1	13055	0.27
chr15_56334596_56334747	0.35	ENSG00000239703	.	12492	0.24
chr2_44464820_44465026	0.35	ENSG00000239052	.	1877	0.34
chr8_134627256_134627424	0.35	ENSG00000212273	.	29628	0.22
chr17_75963626_75963777	0.35	TNRC6C	trinucleotide repeat containing 6C	36548	0.15
chr2_113752762_113752913	0.35	IL36A	interleukin 36, alpha	10201	0.15
chr2_69030270_69030421	0.35	ARHGAP25	Rho GTPase activating protein 25	4018	0.26
chr20_43613655_43613806	0.35	STK4	serine/threonine kinase 4	18563	0.13
chr11_18652208_18652359	0.34	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	3757	0.19
chr7_114616275_114616426	0.34	MDFIC	MyoD family inhibitor domain containing	42426	0.21
chr11_35276728_35276879	0.34	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	10489	0.16
chr1_148195115_148195266	0.34	PPIAL4D	peptidylprolyl isomerase A (cyclophilin A)-like 4D	7346	0.26
chr1_28217565_28217790	0.34	RPA2	replication protein A2, 32kDa	5919	0.13
chr14_61872843_61873172	0.34	PRKCH	protein kinase C, eta	15595	0.24
chr5_73935242_73935400	0.34	HEXB	hexosaminidase B (beta polypeptide)	527	0.69
chr11_108114766_108115122	0.34	ENSG00000206967	.	14613	0.15
chr14_81994783_81994934	0.34	SEL1L	sel-1 suppressor of lin-12-like (C. elegans)	5319	0.33
chr10_86094165_86094316	0.34	CCSER2	coiled-coil serine-rich protein 2	5821	0.27
chr16_25071874_25072133	0.34	ARHGAP17	Rho GTPase activating protein 17	45016	0.14
chr6_16496343_16496494	0.34	ENSG00000265642	.	67664	0.14
chr5_110075238_110075525	0.34	SLC25A46	solute carrier family 25, member 46	639	0.49
chr12_27103883_27104069	0.34	FGFR1OP2	FGFR1 oncogene partner 2	12543	0.14
chr1_231107695_231108082	0.34	TTC13	tetratricopeptide repeat domain 13	6654	0.14
chr14_99726600_99726784	0.34	AL109767.1		2593	0.31
chr11_121198510_121198941	0.34	SC5D	sterol-C5-desaturase	35164	0.22
chr7_159002351_159002502	0.34	VIPR2	vasoactive intestinal peptide receptor 2	64777	0.15
chr2_204721588_204721739	0.34	CTLA4	cytotoxic T-lymphocyte-associated protein 4	10846	0.25
chr15_38944942_38945193	0.34	C15orf53	chromosome 15 open reading frame 53	43732	0.17
chr17_28066618_28066769	0.34	RP11-82O19.1		21428	0.14
chr1_33738764_33738963	0.34	ZNF362	zinc finger protein 362	2687	0.23
chr1_198493797_198494034	0.34	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	15889	0.28
chr4_40248948_40249153	0.33	RHOH	ras homolog family member H	47086	0.14
chr17_33379341_33379559	0.33	ENSG00000238858	.	2063	0.21
chr10_65331748_65331899	0.33	REEP3	receptor accessory protein 3	50700	0.17
chr2_30447134_30447325	0.33	LBH	limb bud and heart development	7168	0.23
chr9_32549312_32549469	0.33	TOPORS-AS1	TOPORS antisense RNA 1	1752	0.26
chr10_33396681_33396832	0.33	ENSG00000263576	.	9192	0.25
chr6_106765578_106765729	0.33	ATG5	autophagy related 5	7639	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.5	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.3	1.0	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.3	1.3	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.2	0.4	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.2	0.6	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.2	0.6	GO:0010040	response to iron(II) ion(GO:0010040)
0.2	1.0	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2	0.2	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.2	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.7	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	0.5	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	0.6	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.4	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.4	GO:0002664	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.5	GO:1904019	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.6	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.9	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	1.0	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.5	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.5	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1	0.8	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.1	0.7	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.3	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	0.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.3	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.6	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.3	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.4	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	2.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0034776	response to histamine(GO:0034776)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	1.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.1	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.2	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.3	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	0.6	GO:0050856	regulation of T cell receptor signaling pathway(GO:0050856)
0.1	0.1	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.1	0.8	GO:0000303	response to superoxide(GO:0000303)
0.1	0.6	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.8	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.3	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	0.3	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.4	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.4	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.1	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.3	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1	0.2	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.8	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.1	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
0.1	0.1	GO:0016233	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1	0.6	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.1	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1	0.1	GO:0036260	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.1	GO:0033080	immature T cell proliferation in thymus(GO:0033080)
0.1	0.2	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.2	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.3	GO:0002063	chondrocyte development(GO:0002063)
0.1	1.1	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.1	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.5	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.2	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.2	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	0.2	GO:0042117	monocyte activation(GO:0042117)
0.1	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.1	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.3	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.3	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.3	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.6	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.4	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.4	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.6	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.5	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.4	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.2	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.2	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	2.0	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.4	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.2	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.1	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0060491	regulation of cell projection assembly(GO:0060491)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.2	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.7	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.2	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0042534	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.3	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.0	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.3	GO:0016073	snRNA metabolic process(GO:0016073)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.8	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.3	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0071071	regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.2	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0045916	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0048925	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0050688	regulation of defense response to virus(GO:0050688)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.4	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0006301	postreplication repair(GO:0006301)
0.0	0.5	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.5	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.3	GO:0035036	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0	0.3	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0018216	peptidyl-arginine methylation(GO:0018216) histone arginine methylation(GO:0034969)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.3	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.4	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.1	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0030449	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0	0.0	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.7	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	1.0	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.3	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:1903513	retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.0	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.0	0.2	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.0	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.2	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.0	GO:0019054	modulation by virus of host process(GO:0019054) modulation by symbiont of host cellular process(GO:0044068)
0.0	0.0	GO:1901890	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.3	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	1.0	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	1.8	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.1	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.0	0.0	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.0	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.3	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0051798	regulation of hair cycle(GO:0042634) positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0006273	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	1.4	GO:0006470	protein dephosphorylation(GO:0006470)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.3	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0045979	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	1.3	GO:0006417	regulation of translation(GO:0006417)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.6	GO:0010827	regulation of glucose transport(GO:0010827)
0.0	0.0	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0	0.0	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.0	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	1.3	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.1	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:0098781	ncRNA transcription(GO:0098781)
0.0	0.0	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	0.2	GO:0001740	Barr body(GO:0001740)
0.1	1.0	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.4	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	1.0	GO:0001772	immunological synapse(GO:0001772)
0.1	0.3	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.1	GO:0000125	PCAF complex(GO:0000125)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.1	GO:0032449	CBM complex(GO:0032449)
0.1	0.6	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.5	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.5	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.6	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.4	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.9	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.3	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.2	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.7	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.3	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.4	GO:0032153	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.1	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	2.2	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.3	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.5	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.0	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0005921	gap junction(GO:0005921)
0.0	1.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	1.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.6	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.3	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.3	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.3	GO:0017053	transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	1.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.7	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.4	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.3	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.7	GO:0030332	cyclin binding(GO:0030332)
0.1	0.3	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	0.8	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.3	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0050733	RS domain binding(GO:0050733)
0.1	0.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.3	GO:0005521	lamin binding(GO:0005521)
0.1	0.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	1.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.4	GO:0009922	fatty acid elongase activity(GO:0009922)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	1.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.9	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.5	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.5	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.2	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.0	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	1.5	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	1.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.8	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	1.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	2.4	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	1.4	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.7	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.5	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.4	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.2	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.2	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.6	GO:0019829	cation-transporting ATPase activity(GO:0019829)
0.0	0.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.5	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.0	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0008493	tetracycline transporter activity(GO:0008493)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.3	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.3	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.7	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	2.9	PID REELIN PATHWAY	Reelin signaling pathway
0.1	3.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.6	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	1.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	2.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.8	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.7	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.4	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.8	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.1	1.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	1.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	1.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	0.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.6	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.7	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.9	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.9	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.0	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0	1.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	1.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.0	0.0	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.1	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation

Results for DUXA

Z-value: 2.02

Motif logo

Transcription factors associated with DUXA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the DUXA motif across conditions

Conditions sorted by the z-value of the DUXA motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: