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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for E2F4

Z-value: 1.08

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Transcription factors associated with E2F4

Gene Symbol	Gene ID	Gene Info
E2F4 Ensembl NCBI GeneCards UniProt	ENSG00000205250.4	E2F4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
E2F4	chr16_67226809_67227108	886	0.288743	0.62	7.6e-02	Click!
E2F4	chr16_67226498_67226740	547	0.478339	0.59	9.6e-02	Click!
E2F4	chr16_67225330_67225481	667	0.368028	0.22	5.6e-01	Click!
E2F4	chr16_67225481_67225632	516	0.483180	-0.15	7.1e-01	Click!
E2F4	chr16_67227161_67227492	1254	0.192017	0.14	7.2e-01	Click!

Activity of the E2F4 motif across conditions

Conditions sorted by the z-value of the E2F4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_37620705_37620902	0.72	SSTR3	somatostatin receptor 3	12441	0.13
chr8_54794402_54794553	0.52	RGS20	regulator of G-protein signaling 20	1023	0.52
chr16_68108782_68108933	0.49	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	10390	0.1
chr19_13044178_13044329	0.48	FARSA	phenylalanyl-tRNA synthetase, alpha subunit	241	0.77
chr14_99729801_99729952	0.47	AL109767.1		591	0.77
chr11_117922812_117923152	0.47	ENSG00000272075	.	14970	0.15
chr3_63848828_63849118	0.45	THOC7	THO complex 7 homolog (Drosophila)	606	0.58
chr9_103114517_103114668	0.45	TEX10	testis expressed 10	261	0.93
chr22_32341357_32341508	0.42	C22orf24	chromosome 22 open reading frame 24	96	0.93
chr5_65018218_65018648	0.40	NLN	neurolysin (metallopeptidase M3 family)	363	0.54
chr21_34392077_34392228	0.39	OLIG2	oligodendrocyte lineage transcription factor 2	6001	0.22
chr15_67359185_67359373	0.38	SMAD3	SMAD family member 3	1096	0.64
chr2_157293041_157293192	0.37	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	119	0.97
chr17_61780737_61780956	0.36	STRADA	STE20-related kinase adaptor alpha	969	0.46
chr6_42359385_42359536	0.35	ENSG00000221252	.	20674	0.21
chr2_219723652_219723803	0.34	WNT6	wingless-type MMTV integration site family, member 6	817	0.51
chrX_17674771_17674922	0.34	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)	21433	0.23
chr4_2787896_2788215	0.34	SH3BP2	SH3-domain binding protein 2	6695	0.21
chr19_40336344_40336545	0.33	FBL	fibrillarin	525	0.75
chr18_22042462_22042613	0.33	HRH4	histamine receptor H4	1844	0.3
chr19_10982774_10983002	0.32	CARM1	coactivator-associated arginine methyltransferase 1	509	0.7
chr18_12308768_12309026	0.32	TUBB6	tubulin, beta 6 class V	635	0.7
chr14_102666358_102666589	0.32	WDR20	WD repeat domain 20	5190	0.21
chr2_161349301_161349452	0.31	RBMS1	RNA binding motif, single stranded interacting protein 1	653	0.81
chr20_5930659_5930947	0.31	TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)	248	0.7
chr15_91106977_91107236	0.31	CRTC3	CREB regulated transcription coactivator 3	29839	0.14
chr15_37392504_37392655	0.31	MEIS2	Meis homeobox 2	125	0.94
chr2_112237136_112237426	0.31	ENSG00000266139	.	158613	0.04
chr4_13485282_13485564	0.31	RAB28	RAB28, member RAS oncogene family	566	0.83
chr5_171542288_171542655	0.30	ENSG00000266671	.	34491	0.16
chr22_25462879_25463030	0.30	KIAA1671	KIAA1671	2982	0.31
chr2_203736496_203736695	0.30	ICA1L	islet cell autoantigen 1,69kDa-like	113	0.97
chr21_36399444_36399595	0.30	RUNX1	runt-related transcription factor 1	21943	0.28
chr10_116252774_116252925	0.30	ABLIM1	actin binding LIM protein 1	5097	0.29
chr20_18448159_18448354	0.30	DZANK1	double zinc ribbon and ankyrin repeat domains 1	427	0.47
chr15_71184789_71184970	0.29	LRRC49	leucine rich repeat containing 49	86	0.56
chr14_101292986_101293251	0.29	AL117190.2		2419	0.08
chr17_41910293_41910444	0.29	MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	170	0.92
chr14_105525570_105525755	0.29	GPR132	G protein-coupled receptor 132	1843	0.34
chrX_128888588_128889150	0.29	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	15871	0.19
chr9_99169894_99170045	0.29	ZNF367	zinc finger protein 367	10642	0.19
chr12_6601923_6602186	0.29	NCAPD2	non-SMC condensin I complex, subunit D2	491	0.47
chr15_101099433_101099584	0.28	RP11-526I2.1		612	0.58
chr16_81870803_81871145	0.28	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	45900	0.18
chr2_48462400_48462551	0.28	ENSG00000201010	.	17761	0.25
chr19_7929792_7929966	0.28	EVI5L	ecotropic viral integration site 5-like	4408	0.09
chr17_75454716_75454867	0.28	SEPT9	septin 9	2343	0.24
chr21_32519368_32519782	0.28	TIAM1	T-cell lymphoma invasion and metastasis 1	17036	0.27
chr6_35275141_35275407	0.28	DEF6	differentially expressed in FDCP 6 homolog (mouse)	2241	0.29
chr9_35618104_35618377	0.27	CD72	CD72 molecule	127	0.91
chr2_230787566_230787813	0.27	TRIP12	thyroid hormone receptor interactor 12	266	0.66
chr11_76494030_76494181	0.27	RP11-21L23.3		1	0.69
chr11_44117733_44117933	0.27	EXT2	exostosin glycosyltransferase 2	60	0.97
chr3_36985785_36985936	0.27	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	688	0.69
chr11_15230197_15230348	0.27	INSC	inscuteable homolog (Drosophila)	59618	0.15
chr15_29135138_29135296	0.26	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2	3908	0.26
chr1_24117965_24118246	0.26	LYPLA2	lysophospholipase II	377	0.76
chr1_154983991_154984142	0.26	ZBTB7B	zinc finger and BTB domain containing 7B	2858	0.1
chr7_150757151_150757478	0.26	SLC4A2	solute carrier family 4 (anion exchanger), member 2	157	0.88
chrX_47488098_47488605	0.26	CFP	complement factor properdin	943	0.43
chr12_4392748_4393028	0.26	CCND2-AS1	CCND2 antisense RNA 1	7538	0.17
chr7_127372868_127373019	0.26	SND1	staphylococcal nuclease and tudor domain containing 1	80709	0.09
chr19_31841356_31841519	0.26	TSHZ3	teashirt zinc finger homeobox 3	984	0.54
chr19_16768091_16768274	0.26	CTC-429P9.4	Small integral membrane protein 7; Uncharacterized protein	2733	0.13
chr19_19316868_19317019	0.26	NR2C2AP	nuclear receptor 2C2-associated protein	2710	0.13
chr2_63286662_63286820	0.26	OTX1	orthodenticle homeobox 1	8804	0.23
chr16_1019409_1019579	0.26	LMF1	lipase maturation factor 1	1372	0.31
chr21_32929864_32930131	0.26	TIAM1	T-cell lymphoma invasion and metastasis 1	1293	0.39
chr7_150174498_150174649	0.26	GIMAP8	GTPase, IMAP family member 8	26855	0.14
chr7_151534819_151535015	0.26	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	22991	0.15
chr5_138851413_138851689	0.25	AC138517.1	Uncharacterized protein	557	0.68
chr12_57635535_57635686	0.25	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	1135	0.31
chr2_71356997_71357205	0.25	MCEE	methylmalonyl CoA epimerase	243	0.59
chr1_38454975_38455189	0.25	SF3A3	splicing factor 3a, subunit 3, 60kDa	577	0.62
chr14_98441802_98442041	0.25	C14orf64	chromosome 14 open reading frame 64	2462	0.45
chr17_19015396_19015547	0.25	ENSG00000262202	.	478	0.65
chr5_142149375_142149625	0.25	ARHGAP26	Rho GTPase activating protein 26	449	0.88
chr11_74169959_74170165	0.25	KCNE3	potassium voltage-gated channel, Isk-related family, member 3	3350	0.16
chr5_126317848_126317999	0.25	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	48577	0.17
chr3_53202293_53202538	0.25	PRKCD	protein kinase C, delta	3270	0.22
chr11_117186964_117187239	0.25	BACE1	beta-site APP-cleaving enzyme 1	126	0.94
chr2_87769897_87770221	0.24	RP11-1399P15.1		7494	0.31
chr20_55974994_55975197	0.24	RP4-800J21.3		6977	0.16
chr3_52255710_52256010	0.24	TLR9	toll-like receptor 9	4319	0.11
chr1_145395576_145396119	0.24	ENSG00000201558	.	13090	0.14
chr11_1801564_1801715	0.24	CTSD	cathepsin D	16417	0.08
chr18_20716662_20716943	0.24	ENSG00000222999	.	326	0.57
chr9_95783100_95783251	0.24	FGD3	FYVE, RhoGEF and PH domain containing 3	5833	0.21
chr14_91814952_91815599	0.24	ENSG00000265856	.	15218	0.22
chr13_24829233_24829410	0.24	SPATA13-AS1	SPATA13 antisense RNA 1	744	0.63
chr16_89927127_89927278	0.24	TCF25	transcription factor 25 (basic helix-loop-helix)	12812	0.13
chr15_68375595_68375936	0.24	PIAS1	protein inhibitor of activated STAT, 1	28851	0.22
chr10_63870514_63870665	0.24	ENSG00000221094	.	5385	0.29
chr12_66219604_66219755	0.24	HMGA2	high mobility group AT-hook 2	776	0.69
chr10_17272231_17272382	0.24	VIM	vimentin	302	0.5
chrX_106448945_106449104	0.24	NUP62CL	nucleoporin 62kDa C-terminal like	639	0.5
chr20_61638770_61638921	0.24	BHLHE23	basic helix-loop-helix family, member e23	458	0.81
chr3_183979642_183979943	0.24	CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	541	0.6
chr14_21150005_21150238	0.23	RNASE4	ribonuclease, RNase A family, 4	2138	0.14
chr9_99983071_99983222	0.23	CCDC180	coiled-coil domain containing 180	17619	0.21
chr7_33701123_33701274	0.23	RP11-89N17.1	HCG1643653; Uncharacterized protein	64395	0.13
chr20_32837057_32837353	0.23	ASIP	agouti signaling protein	10966	0.17
chr7_27205594_27205875	0.23	HOXA9	homeobox A9	585	0.43
chr9_132816429_132816580	0.23	GPR107	G protein-coupled receptor 107	519	0.79
chr3_138067657_138067808	0.23	MRAS	muscle RAS oncogene homolog	40	0.98
chr12_6876238_6876445	0.23	MLF2	myeloid leukemia factor 2	300	0.67
chr17_74269472_74269623	0.23	QRICH2	glutamine rich 2	6891	0.13
chr5_114545827_114545978	0.23	CTC-428G20.2		21642	0.16
chr9_14315059_14315375	0.23	NFIB	nuclear factor I/B	636	0.73
chr5_14596125_14596582	0.23	FAM105A	family with sequence similarity 105, member A	14469	0.24
chr7_150674322_150674753	0.23	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	477	0.73
chr17_77777762_77777981	0.22	CBX8	chromobox homolog 8	2539	0.19
chr8_146125496_146125701	0.22	ZNF250	zinc finger protein 250	1209	0.41
chr2_171676330_171676481	0.22	AC007405.8		1858	0.27
chr7_21985572_21985928	0.22	CDCA7L	cell division cycle associated 7-like	48	0.99
chr9_131669773_131669924	0.22	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1	13326	0.11
chr22_46068446_46068662	0.22	ATXN10	ataxin 10	875	0.64
chr8_145002100_145002251	0.22	PLEC	plectin	996	0.39
chr19_52996325_52996476	0.22	ZNF578	zinc finger protein 578	317	0.84
chr2_29236792_29237319	0.22	FAM179A	family with sequence similarity 179, member A	4072	0.19
chr4_126236035_126236377	0.21	FAT4	FAT atypical cadherin 4	1348	0.58
chr9_129387391_129387562	0.21	LMX1B	LIM homeobox transcription factor 1, beta	10728	0.16
chr22_37623875_37624507	0.21	SSTR3	somatostatin receptor 3	15829	0.12
chr17_48134073_48134477	0.21	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	471	0.75
chr3_157155814_157155965	0.21	PTX3	pentraxin 3, long	1311	0.55
chr19_45908936_45909178	0.21	CD3EAP	CD3e molecule, epsilon associated protein	410	0.51
chr1_6055265_6055416	0.21	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	2569	0.24
chr3_193987519_193987707	0.21	CPN2	carboxypeptidase N, polypeptide 2	84434	0.08
chr18_74811464_74812005	0.21	MBP	myelin basic protein	5483	0.32
chr11_118811293_118811572	0.21	ENSG00000239726	.	9512	0.08
chrX_150153284_150153533	0.21	HMGB3	high mobility group box 3	596	0.75
chr17_75889796_75889947	0.21	FLJ45079		11212	0.22
chrX_135230186_135230374	0.21	FHL1	four and a half LIM domains 1	10	0.98
chr19_50063674_50064142	0.21	NOSIP	nitric oxide synthase interacting protein	21	0.93
chr9_100617168_100617452	0.21	FOXE1	forkhead box E1 (thyroid transcription factor 2)	1774	0.38
chr14_24837393_24837740	0.21	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	19	0.94
chr2_106804645_106804858	0.21	UXS1	UDP-glucuronate decarboxylase 1	6004	0.25
chr1_21978624_21978775	0.20	RAP1GAP	RAP1 GTPase activating protein	351	0.89
chr2_231437706_231437857	0.20	AC010149.4		6867	0.2
chr7_1456845_1457076	0.20	MICALL2	MICAL-like 2	42002	0.12
chr19_1450029_1450180	0.20	APC2	adenomatosis polyposis coli 2	44	0.93
chr16_57176887_57177289	0.20	CPNE2	copine II	23977	0.12
chr20_19997607_19997892	0.20	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	11	0.98
chr3_45187270_45187501	0.20	CDCP1	CUB domain containing protein 1	529	0.82
chr11_36616334_36616601	0.20	C11orf74	chromosome 11 open reading frame 74	67	0.63
chr10_63663919_63664225	0.20	ARID5B	AT rich interactive domain 5B (MRF1-like)	3013	0.33
chr1_150550855_150551146	0.20	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1006	0.32
chr12_57636992_57637222	0.20	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	2632	0.14
chr19_56014839_56015099	0.20	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)	9711	0.08
chr12_96184490_96184641	0.20	NTN4	netrin 4	23	0.97
chr18_45693523_45693802	0.20	ZBTB7C	zinc finger and BTB domain containing 7C	1725	0.38
chr20_47379698_47379939	0.20	ENSG00000251876	.	23833	0.24
chr17_55360579_55360787	0.20	MSI2	musashi RNA-binding protein 2	2522	0.39
chr2_6924565_6924716	0.20	AC017076.5		49022	0.15
chr5_1799046_1799396	0.20	MRPL36	mitochondrial ribosomal protein L36	643	0.67
chr17_46805969_46806120	0.19	HOXB13	homeobox B13	496	0.65
chr8_8670148_8670299	0.19	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	80932	0.08
chr2_61272587_61272742	0.19	KIAA1841	KIAA1841	20404	0.15
chr2_240182188_240182405	0.19	ENSG00000265215	.	44861	0.12
chr10_7860991_7861192	0.19	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	624	0.76
chr2_62425937_62426123	0.19	B3GNT2	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	2782	0.24
chr18_60382474_60382625	0.19	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	123	0.97
chr9_22446679_22446830	0.19	DMRTA1	DMRT-like family A1	86	0.99
chr2_63284454_63284605	0.19	OTX1	orthodenticle homeobox 1	6592	0.24
chr13_99703300_99703553	0.19	ENSG00000207298	.	25938	0.17
chr20_30639419_30639649	0.19	HCK	hemopoietic cell kinase	457	0.65
chr5_1799598_1799749	0.19	MRPL36	mitochondrial ribosomal protein L36	191	0.93
chr16_88766157_88766414	0.19	RNF166	ring finger protein 166	171	0.86
chr3_32479509_32479795	0.19	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	46121	0.14
chr6_153303203_153303466	0.19	FBXO5	F-box protein 5	819	0.52
chr15_92404124_92404311	0.19	SLCO3A1	solute carrier organic anion transporter family, member 3A1	6866	0.27
chrX_55027132_55027456	0.19	APEX2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	504	0.73
chr17_30335102_30335253	0.19	LRRC37B	leucine rich repeat containing 37B	170	0.95
chr17_76110986_76111137	0.19	ENSG00000204282	.	3181	0.16
chr2_7061705_7061856	0.19	ENSG00000228203	.	2940	0.24
chr19_36443027_36443178	0.19	LRFN3	leucine rich repeat and fibronectin type III domain containing 3	15080	0.09
chr1_28586799_28587133	0.19	SESN2	sestrin 2	928	0.45
chr12_64061940_64062091	0.19	DPY19L2	dpy-19-like 2 (C. elegans)	300	0.93
chr20_60962587_60962934	0.19	RPS21	ribosomal protein S21	379	0.79
chr2_110371414_110371565	0.19	SEPT10	septin 10	3	0.88
chr22_30663660_30663811	0.19	OSM	oncostatin M	906	0.4
chr15_91138025_91138489	0.19	CRTC3	CREB regulated transcription coactivator 3	1312	0.32
chr1_145610669_145610820	0.19	POLR3C	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	140	0.69
chr3_153839356_153839507	0.19	ARHGEF26	Rho guanine nucleotide exchange factor (GEF) 26	202	0.64
chr9_139948636_139948800	0.19	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	221	0.75
chr14_89830784_89831443	0.19	RP11-356K23.2		9709	0.17
chr3_9177794_9177945	0.19	SRGAP3-AS2	SRGAP3 antisense RNA 2	56308	0.12
chr15_31622016_31622167	0.19	KLF13	Kruppel-like factor 13	3033	0.39
chr19_8386904_8387224	0.19	RPS28	ribosomal protein S28	680	0.38
chr3_124449486_124449637	0.19	UMPS	uridine monophosphate synthetase	262	0.87
chr10_73514684_73515259	0.19	C10orf54	chromosome 10 open reading frame 54	2416	0.29
chr16_3640725_3640876	0.18	NLRC3	NLR family, CARD domain containing 3	13399	0.13
chr17_45266002_45266457	0.18	CDC27	cell division cycle 27	313	0.84
chr16_3122337_3122494	0.18	ENSG00000252561	.	2891	0.09
chrX_39712527_39712734	0.18	ENSG00000263972	.	15815	0.27
chr1_209957444_209957681	0.18	C1orf74	chromosome 1 open reading frame 74	342	0.82
chr20_3062971_3063207	0.18	AVP	arginine vasopressin	2281	0.19
chr13_40177019_40177302	0.18	LHFP	lipoma HMGIC fusion partner	148	0.97
chr11_75294844_75295036	0.18	CTD-2530H12.4		699	0.6
chr2_68546906_68547171	0.18	CNRIP1	cannabinoid receptor interacting protein 1	19	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.3	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:0009405	pathogenesis(GO:0009405)
0.1	0.2	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:1903224	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.2	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.1	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.1	0.2	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.2	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.4	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.3	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.2	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.2	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.2	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.2	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.2	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.2	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.4	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.2	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.2	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0061140	lung secretory cell differentiation(GO:0061140)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0085029	extracellular matrix assembly(GO:0085029)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.2	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.2	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.0	GO:0035872	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0090398	cellular senescence(GO:0090398)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.3	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094)
0.0	0.2	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0035930	obsolete regulation of natriuresis(GO:0003078) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.0	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.0	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.3	GO:1903845	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.1	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.0	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0060391	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0	0.0	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.0	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0008216	spermidine metabolic process(GO:0008216)
0.0	0.0	GO:0051153	regulation of striated muscle cell differentiation(GO:0051153)
0.0	0.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.0	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.0	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0001652	granular component(GO:0001652)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.2	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.5	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.3	GO:0005605	basal lamina(GO:0005605)
0.0	0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.0	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.4	GO:0005776	autophagosome(GO:0005776)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.4	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.4	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.0	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.5	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.8	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation