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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for EGR1_EGR4

Z-value: 2.83

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Transcription factors associated with EGR1_EGR4

Gene Symbol	Gene ID	Gene Info
EGR1 Ensembl NCBI GeneCards UniProt	ENSG00000120738.7	early growth response 1
EGR4 Ensembl NCBI GeneCards UniProt	ENSG00000135625.6	early growth response 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_137823997_137824289	EGR1	22964	0.138464	0.79	1.1e-02	Click!
chr5_137803266_137803417	EGR1	2162	0.274062	0.78	1.3e-02	Click!
chr5_137797443_137797594	EGR1	3661	0.202690	0.72	2.9e-02	Click!
chr5_137828425_137828681	EGR1	27374	0.128697	0.66	5.2e-02	Click!
chr5_137822263_137822414	EGR1	21159	0.142280	0.59	9.3e-02	Click!
chr2_73518521_73518674	EGR4	2232	0.231451	0.60	8.8e-02	Click!
chr2_73521098_73521253	EGR4	342	0.840048	-0.51	1.6e-01	Click!
chr2_73518139_73518290	EGR4	2615	0.207642	0.28	4.7e-01	Click!
chr2_73520777_73521029	EGR4	70	0.963149	0.25	5.1e-01	Click!
chr2_73518752_73518927	EGR4	1990	0.252634	-0.18	6.5e-01	Click!

Activity of the EGR1_EGR4 motif across conditions

Conditions sorted by the z-value of the EGR1_EGR4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_21762368_21762519	1.64	OSBPL1A	oxysterol binding protein-like 1A	2644	0.2
chr6_17033705_17033856	1.46	STMND1	stathmin domain containing 1	68709	0.14
chr14_34161217_34161368	1.42	NPAS3	neuronal PAS domain protein 3	43155	0.21
chr11_68659074_68659228	1.36	MRPL21	mitochondrial ribosomal protein L21	12095	0.15
chr11_12562425_12562576	1.32	PARVA	parvin, alpha	88218	0.09
chr8_22026915_22027066	1.30	BMP1	bone morphogenetic protein 1	4190	0.13
chr9_132236336_132236633	1.27	ENSG00000264298	.	4351	0.26
chr9_139462117_139462567	1.24	RP11-611D20.2		18760	0.09
chr2_110883713_110883864	1.24	ENSG00000212091	.	613	0.67
chr19_16177822_16178237	1.14	TPM4	tropomyosin 4	198	0.94
chr17_62051771_62052003	1.12	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	1609	0.28
chr5_10453675_10453826	1.10	ROPN1L	rhophilin associated tail protein 1-like	11762	0.14
chr1_3387685_3387836	1.07	ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	428	0.85
chr1_38596872_38597023	1.03	ENSG00000265596	.	42044	0.15
chr17_36609068_36609612	1.02	ENSG00000260833	.	652	0.66
chr12_132379887_132380588	1.00	ULK1	unc-51 like autophagy activating kinase 1	1041	0.51
chr22_29704543_29704694	0.97	GAS2L1	growth arrest-specific 2 like 1	1570	0.24
chr17_48763783_48763934	0.95	RP11-294J22.6		6951	0.12
chr2_102679125_102679276	0.94	IL1R1	interleukin 1 receptor, type I	1804	0.43
chr1_15224545_15224696	0.91	KAZN	kazrin, periplakin interacting protein	26006	0.26
chr16_28743370_28743521	0.87	EIF3C	eukaryotic translation initiation factor 3, subunit C	18865	0.11
chr1_203432717_203432868	0.86	PRELP	proline/arginine-rich end leucine-rich repeat protein	12164	0.21
chr6_5083119_5083270	0.85	PPP1R3G	protein phosphatase 1, regulatory subunit 3G	2526	0.31
chr19_50355314_50356474	0.83	PTOV1-AS1	PTOV1 antisense RNA 1	961	0.21
chr6_52377718_52377869	0.83	TRAM2	translocation associated membrane protein 2	63920	0.12
chr1_200379417_200380026	0.82	ZNF281	zinc finger protein 281	537	0.87
chr16_28394449_28394600	0.82	NPIPB6	nuclear pore complex interacting protein family, member B6	19695	0.15
chr16_84211484_84211635	0.81	DNAAF1	dynein, axonemal, assembly factor 1	1812	0.22
chr12_26391441_26391592	0.81	RP11-283G6.5		33239	0.16
chr21_44144329_44144647	0.80	AP001627.1		17380	0.2
chr9_124009409_124009697	0.80	GSN	gelsolin	20785	0.13
chr7_1600035_1600318	0.80	TMEM184A	transmembrane protein 184A	281	0.89
chr19_2384138_2384400	0.80	TMPRSS9	transmembrane protease, serine 9	5515	0.13
chr3_11195342_11196026	0.80	HRH1	histamine receptor H1	530	0.86
chr3_126326261_126326475	0.79	TXNRD3NB	thioredoxin reductase 3 neighbor	1030	0.43
chr13_22257583_22257734	0.79	FGF9	fibroblast growth factor 9	12136	0.25
chr2_75092116_75092366	0.78	HK2	hexokinase 2	29944	0.2
chr1_161054878_161055029	0.78	RP11-544M22.8		698	0.42
chr21_47239386_47239537	0.78	AL592528.1		16872	0.19
chr6_44044467_44044818	0.78	RP5-1120P11.1		2253	0.28
chr1_117034892_117035178	0.77	ENSG00000200547	.	39877	0.12
chr2_236516678_236516829	0.77	ENSG00000221704	.	36178	0.19
chr11_122311887_122312369	0.76	ENSG00000252776	.	7790	0.23
chr17_45929630_45929860	0.75	SP6	Sp6 transcription factor	1186	0.32
chr2_43152306_43152732	0.74	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	132787	0.05
chr1_26026064_26026215	0.74	MAN1C1	mannosidase, alpha, class 1C, member 1	9954	0.18
chr15_74715944_74716095	0.73	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	9982	0.14
chr22_35789765_35790134	0.73	MCM5	minichromosome maintenance complex component 5	6107	0.2
chr3_52039773_52040512	0.73	RPL29	ribosomal protein L29	10184	0.09
chr2_47313454_47313781	0.73	AC073283.7		18656	0.18
chr3_134034709_134034891	0.72	AMOTL2	angiomotin like 2	55954	0.13
chr12_291572_291838	0.72	RP11-283I3.1		10497	0.13
chr19_4718186_4718464	0.72	DPP9	dipeptidyl-peptidase 9	425	0.75
chr1_231410009_231410185	0.72	ENSG00000222407	.	7173	0.17
chr3_25627117_25627268	0.72	ENSG00000272166	.	30095	0.18
chr17_36031578_36031729	0.72	DDX52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	28160	0.14
chr16_22825003_22825167	0.72	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	413	0.91
chr5_167377158_167377309	0.71	CTC-353G13.1		3241	0.26
chr8_143695048_143695766	0.71	ARC	activity-regulated cytoskeleton-associated protein	1426	0.34
chr7_562019_562238	0.70	PDGFA	platelet-derived growth factor alpha polypeptide	2195	0.31
chr14_34060608_34060759	0.70	NPAS3	neuronal PAS domain protein 3	143764	0.05
chrX_39964958_39965304	0.69	BCOR	BCL6 corepressor	8475	0.32
chr4_122618383_122618871	0.69	ANXA5	annexin A5	359	0.9
chr4_81228983_81229134	0.69	C4orf22	chromosome 4 open reading frame 22	27816	0.2
chr12_124997368_124997619	0.68	NCOR2	nuclear receptor corepressor 2	5347	0.33
chr1_208137490_208137641	0.68	CD34	CD34 molecule	52818	0.17
chr11_8739126_8739517	0.68	ST5	suppression of tumorigenicity 5	62	0.96
chr2_228521831_228521982	0.68	C2orf83	chromosome 2 open reading frame 83	23870	0.17
chr19_12984198_12984424	0.66	ENSG00000265759	.	767	0.35
chr10_129789919_129790600	0.66	PTPRE	protein tyrosine phosphatase, receptor type, E	4651	0.3
chr8_124693223_124693374	0.65	KLHL38	kelch-like family member 38	28108	0.16
chr7_16737552_16737703	0.65	BZW2	basic leucine zipper and W2 domains 2	9477	0.18
chr11_43597234_43597910	0.65	ENSG00000199077	.	5372	0.24
chr3_131121230_131121775	0.65	NUDT16	nudix (nucleoside diphosphate linked moiety X)-type motif 16	20873	0.15
chr21_46890680_46890997	0.65	COL18A1	collagen, type XVIII, alpha 1	15414	0.18
chr2_183458563_183458714	0.64	PDE1A	phosphodiesterase 1A, calmodulin-dependent	71173	0.12
chr7_47596592_47596743	0.64	TNS3	tensin 3	17468	0.27
chr15_77361922_77362567	0.64	TSPAN3	tetraspanin 3	1132	0.42
chr5_79287103_79287365	0.64	MTX3	metaxin 3	152	0.96
chr9_110925898_110926343	0.64	ENSG00000222512	.	195089	0.03
chr4_77869465_77869616	0.63	SEPT11	septin 11	1316	0.51
chr16_88878537_88878783	0.63	APRT	adenine phosphoribosyltransferase	308	0.79
chr7_2557138_2557386	0.63	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	235	0.91
chrX_3181986_3182137	0.63	CXorf28	chromosome X open reading frame 28	7800	0.28
chr2_133174456_133174874	0.63	GPR39	G protein-coupled receptor 39	518	0.81
chr5_34564369_34564520	0.62	RAI14	retinoic acid induced 14	91898	0.09
chr22_47330400_47330827	0.62	ENSG00000221672	.	86810	0.1
chr19_8428720_8428871	0.62	ANGPTL4	angiopoietin-like 4	240	0.85
chr12_122158077_122158228	0.61	TMEM120B	transmembrane protein 120B	7451	0.2
chr1_201462888_201463289	0.61	CSRP1	cysteine and glycine-rich protein 1	2613	0.23
chr11_65431282_65431834	0.61	RELA	v-rel avian reticuloendotheliosis viral oncogene homolog A	993	0.33
chr16_11226501_11226734	0.61	CLEC16A	C-type lectin domain family 16, member A	6692	0.2
chr8_103548164_103548536	0.61	ENSG00000252593	.	2783	0.24
chr17_47938739_47938890	0.61	TAC4	tachykinin 4 (hemokinin)	13435	0.16
chr12_3108487_3108638	0.61	TEAD4	TEA domain family member 4	11648	0.17
chr9_35604415_35605122	0.60	TESK1	testis-specific kinase 1	599	0.54
chr15_45952586_45952737	0.60	SQRDL	sulfide quinone reductase-like (yeast)	1382	0.46
chr9_20679284_20679435	0.60	FOCAD	focadhesin	21051	0.18
chr10_127931048_127931232	0.60	ENSG00000222740	.	96989	0.08
chr1_55446055_55446206	0.59	TMEM61	transmembrane protein 61	335	0.86
chr10_830672_830823	0.59	LARP4B	La ribonucleoprotein domain family, member 4B	33039	0.18
chr6_112651418_112651569	0.58	RFPL4B	ret finger protein-like 4B	17039	0.19
chr5_136541942_136542093	0.58	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	107210	0.08
chr5_17095100_17095411	0.58	ENSG00000206814	.	22540	0.18
chr7_101457741_101458764	0.58	CUX1	cut-like homeobox 1	707	0.73
chr17_10747210_10747361	0.58	PIRT	phosphoinositide-interacting regulator of transient receptor potential channels	5523	0.22
chr5_64362201_64362614	0.57	ENSG00000207439	.	56789	0.17
chrX_153095181_153095332	0.57	PDZD4	PDZ domain containing 4	95	0.94
chr4_1003833_1004600	0.57	FGFRL1	fibroblast growth factor receptor-like 1	449	0.75
chr12_88375416_88375567	0.57	C12orf50	chromosome 12 open reading frame 50	46249	0.15
chr1_203122083_203122234	0.57	RP11-335O13.8		130	0.94
chr12_48109700_48109851	0.57	ENDOU	endonuclease, polyU-specific	1657	0.33
chr17_79070617_79071314	0.56	BAIAP2	BAI1-associated protein 2	414	0.74
chr20_35083215_35083366	0.56	DLGAP4	discs, large (Drosophila) homolog-associated protein 4	6860	0.23
chr8_38333381_38333680	0.56	FGFR1	fibroblast growth factor receptor 1	7178	0.18
chr16_88518586_88519370	0.56	ZFPM1	zinc finger protein, FOG family member 1	747	0.63
chr3_111622183_111622334	0.56	PHLDB2	pleckstrin homology-like domain, family B, member 2	8199	0.25
chr16_53907072_53907223	0.56	FTO	fat mass and obesity associated	13682	0.26
chr10_104315653_104315804	0.56	ENSG00000242311	.	30006	0.11
chr17_19267997_19268148	0.56	B9D1	B9 protein domain 1	1728	0.22
chr6_147135992_147136143	0.55	ADGB	androglobin	13072	0.25
chr8_126556994_126557152	0.55	ENSG00000266452	.	100266	0.08
chr5_153990433_153990710	0.55	ENSG00000264760	.	14939	0.21
chr1_246149947_246150098	0.55	RP11-83A16.1		46831	0.18
chr19_58238997_58239148	0.55	ZNF671	zinc finger protein 671	80	0.94
chr11_64010544_64010731	0.55	FKBP2	FK506 binding protein 2, 13kDa	1417	0.15
chr10_24737043_24737194	0.55	KIAA1217	KIAA1217	1244	0.56
chr10_47750225_47750376	0.55	ANXA8L2	annexin A8-like 2	3264	0.22
chr3_71585804_71586230	0.54	ENSG00000221264	.	5223	0.23
chr6_40925892_40926043	0.54	UNC5CL	unc-5 homolog C (C. elegans)-like	76907	0.08
chr4_3287517_3288111	0.54	RGS12	regulator of G-protein signaling 12	22948	0.2
chr13_111033026_111033177	0.54	ENSG00000238629	.	33451	0.17
chr11_417004_417487	0.54	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	80	0.94
chr1_234858071_234858911	0.54	IRF2BP2	interferon regulatory factor 2 binding protein 2	113220	0.06
chr17_75830754_75831206	0.54	FLJ45079		47679	0.16
chr14_75039240_75039720	0.54	LTBP2	latent transforming growth factor beta binding protein 2	39295	0.13
chr15_71407249_71407551	0.54	CT62	cancer/testis antigen 62	406	0.88
chr8_79428082_79428233	0.54	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	217	0.96
chr9_137271552_137271741	0.54	ENSG00000263897	.	389	0.89
chr17_15280248_15280399	0.53	ENSG00000239888	.	31378	0.14
chr16_86261645_86261796	0.53	ENSG00000199949	.	47409	0.19
chr22_50422080_50422460	0.53	IL17REL	interleukin 17 receptor E-like	24851	0.15
chr17_6679303_6679767	0.53	FBXO39	F-box protein 39	7	0.97
chr8_130896094_130896358	0.53	ENSG00000200075	.	15264	0.2
chr4_26527293_26527444	0.53	CCKAR	cholecystokinin A receptor	35284	0.18
chr19_5048583_5048873	0.53	KDM4B	lysine (K)-specific demethylase 4B	32392	0.18
chr2_220267573_220267759	0.53	DNPEP	aspartyl aminopeptidase	2922	0.14
chr1_156675699_156676565	0.53	CRABP2	cellular retinoic acid binding protein 2	524	0.6
chr15_40630687_40631051	0.52	C15orf52	chromosome 15 open reading frame 52	535	0.56
chr1_94559548_94560093	0.52	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	26861	0.17
chr6_139139154_139139453	0.52	ECT2L	epithelial cell transforming sequence 2 oncogene-like	3624	0.26
chr7_5595160_5595387	0.52	CTB-161C1.1		1089	0.41
chr13_76223017_76223168	0.52	LMO7	LIM domain 7	12633	0.18
chr6_166980327_166980478	0.52	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	22224	0.19
chr17_45365957_45366108	0.52	RP11-290H9.4		17019	0.13
chr18_20247259_20247410	0.52	ENSG00000206827	.	19789	0.23
chr19_49564829_49564980	0.52	NTF4	neurotrophin 4	350	0.59
chr19_42787089_42787782	0.51	CIC	capicua transcriptional repressor	737	0.45
chr11_65255454_65256217	0.51	AP000769.1	Uncharacterized protein	33107	0.08
chr2_127842898_127843179	0.51	BIN1	bridging integrator 1	21539	0.23
chr4_10097090_10097875	0.51	ENSG00000264931	.	17166	0.14
chr4_5035629_5036207	0.51	CYTL1	cytokine-like 1	14719	0.22
chr16_85207698_85207849	0.51	CTC-786C10.1		2891	0.33
chr15_74716383_74716612	0.51	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	9504	0.14
chr19_8672060_8672211	0.51	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	1048	0.45
chr13_26649032_26649183	0.50	SHISA2	shisa family member 2	23938	0.24
chr12_71376158_71376309	0.50	PTPRR	protein tyrosine phosphatase, receptor type, R	61610	0.13
chr3_125986540_125986691	0.50	ALDH1L1-AS2	ALDH1L1 antisense RNA 2	60517	0.1
chr5_106892916_106893173	0.50	EFNA5	ephrin-A5	113284	0.07
chr2_239505716_239505867	0.50	AC016999.2		169421	0.03
chr20_34129990_34130743	0.50	ERGIC3	ERGIC and golgi 3	487	0.7
chr21_39243678_39243829	0.50	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	41804	0.18
chr11_14051655_14051806	0.50	ENSG00000212365	.	104802	0.07
chr13_52945814_52946215	0.50	ENSG00000199605	.	28125	0.16
chr2_173139735_173139887	0.50	ENSG00000238572	.	118963	0.05
chr10_48277816_48278279	0.50	ANXA8	annexin A8	22694	0.13
chr17_36862672_36863533	0.50	CTB-58E17.3		588	0.44
chr10_22915743_22916374	0.50	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	35416	0.22
chr11_66079672_66080096	0.49	RP11-867G23.13		440	0.57
chr22_50741608_50741759	0.49	PLXNB2	plexin B2	1792	0.18
chr6_7165580_7166040	0.49	RP11-405O10.2		17506	0.17
chr21_45426599_45426750	0.49	TRAPPC10	trafficking protein particle complex 10	5526	0.18
chr16_86668948_86669099	0.49	FOXL1	forkhead box L1	56908	0.12
chr1_46985901_46986151	0.49	DMBX1	diencephalon/mesencephalon homeobox 1	13357	0.14
chr1_203483478_203483842	0.49	OPTC	opticin	18562	0.2
chr6_42104236_42104387	0.49	C6orf132	chromosome 6 open reading frame 132	5871	0.16
chr9_35756772_35756935	0.49	RP11-112J3.15		1084	0.26
chr19_17358096_17358247	0.49	NR2F6	nuclear receptor subfamily 2, group F, member 6	1422	0.2
chr2_218793437_218793804	0.49	TNS1	tensin 1	8265	0.24
chr21_44593603_44593859	0.48	CRYAA	crystallin, alpha A	3465	0.21
chr17_81066971_81067122	0.48	METRNL	meteorin, glial cell differentiation regulator-like	15052	0.24
chr16_57662544_57662789	0.48	GPR56	G protein-coupled receptor 56	64	0.96
chr1_210484845_210485129	0.48	HHAT	hedgehog acyltransferase	16609	0.23
chr2_3751403_3751554	0.48	DCDC2C	doublecortin domain containing 2C	25	0.79
chr19_47407880_47408230	0.48	ARHGAP35	Rho GTPase activating protein 35	13878	0.17
chr12_175093_175819	0.48	IQSEC3	IQ motif and Sec7 domain 3	475	0.8
chr11_118791485_118792723	0.48	BCL9L	B-cell CLL/lymphoma 9-like	2491	0.13
chr1_21565804_21565955	0.48	RP3-329E20.2		26696	0.16
chr6_131924415_131924566	0.48	MED23	mediator complex subunit 23	6845	0.18
chr16_4103086_4103844	0.47	RP11-462G12.4		21452	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0007386	compartment pattern specification(GO:0007386)
0.2	0.5	GO:0009405	pathogenesis(GO:0009405)
0.2	0.7	GO:0071731	response to nitric oxide(GO:0071731)
0.2	0.5	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2	0.5	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2	0.5	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.2	0.2	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.4	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	0.4	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.4	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.4	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.4	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.4	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.5	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.3	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1	0.5	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.3	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1	0.3	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.1	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	0.4	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.4	GO:0060539	diaphragm development(GO:0060539)
0.1	0.3	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	1.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.1	0.9	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.3	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1	0.3	GO:2000053	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.3	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.6	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.4	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	0.3	GO:0060992	response to fungicide(GO:0060992)
0.1	0.3	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.3	GO:0010107	potassium ion import(GO:0010107)
0.1	0.2	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.5	GO:0043954	cellular component maintenance(GO:0043954)
0.1	0.3	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.2	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.6	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.1	GO:0090103	cochlea morphogenesis(GO:0090103)
0.1	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	0.6	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.5	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.3	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	0.2	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.3	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.5	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.2	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.1	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.2	GO:0035872	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.1	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1	0.1	GO:0061339	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	0.3	GO:0046541	saliva secretion(GO:0046541)
0.1	0.5	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.1	GO:0051608	histamine transport(GO:0051608)
0.1	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.2	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.2	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.3	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.1	GO:0060073	micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.2	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.1	GO:0060856	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) establishment of blood-brain barrier(GO:0060856)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.3	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.2	GO:1904748	regulation of apoptotic process involved in morphogenesis(GO:1902337) regulation of apoptotic process involved in development(GO:1904748)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.0	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.3	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.3	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.4	GO:0071450	removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.3	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.4	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.2	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.6	GO:0009268	response to pH(GO:0009268)
0.0	0.2	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	0.2	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.2	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:1901890	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.5	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.2	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.2	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:2000108	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.5	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.3	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	1.2	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.2	GO:0060840	artery morphogenesis(GO:0048844) artery development(GO:0060840)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.3	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.4	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.0	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.5	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532) astrocyte activation(GO:0048143)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.2	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0032402	establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0	0.7	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.0	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.2	GO:0030916	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.2	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0002548	monocyte chemotaxis(GO:0002548)
0.0	0.1	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.0	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.5	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0	0.1	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.1	GO:0034969	histone arginine methylation(GO:0034969)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0033003	regulation of mast cell activation(GO:0033003)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:0048247	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.0	GO:0072179	regulation of asymmetric cell division(GO:0009786) nephric duct formation(GO:0072179)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.0	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.1	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.1	GO:0043303	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0	0.0	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.2	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.5	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0044851	anagen(GO:0042640) hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0014052	gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.5	GO:1902653	secondary alcohol biosynthetic process(GO:1902653)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:1902743	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.2	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.0	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0045988	negative regulation of muscle contraction(GO:0045932) negative regulation of striated muscle contraction(GO:0045988)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0060669	embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0046133	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.2	GO:0045445	myoblast differentiation(GO:0045445)
0.0	0.0	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.2	GO:0006298	mismatch repair(GO:0006298)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.6	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.5	GO:0007623	circadian rhythm(GO:0007623)
0.0	0.1	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.2	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.0	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.0	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.0	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.1	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.0	GO:0051904	pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)
0.0	0.0	GO:0007164	establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0	0.3	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.0	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.0	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.0	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.0	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.0	GO:0032527	retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0	0.0	GO:0016114	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) terpenoid biosynthetic process(GO:0016114)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.2	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0043526	obsolete neuroprotection(GO:0043526)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.4	GO:0050909	sensory perception of taste(GO:0050909)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	0.6	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.5	GO:0030904	retromer complex(GO:0030904)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.3	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.6	GO:0002102	podosome(GO:0002102)
0.1	0.2	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.3	GO:0002080	acrosomal membrane(GO:0002080)
0.1	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.4	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.3	GO:0042599	lamellar body(GO:0042599)
0.1	0.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.2	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.3	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	1.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0043205	fibril(GO:0043205)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.5	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.2	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0016011	dystroglycan complex(GO:0016011)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.8	GO:0031514	motile cilium(GO:0031514)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.5	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.3	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	1.6	GO:0005925	focal adhesion(GO:0005925)
0.0	0.3	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0030286	dynein complex(GO:0030286)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	1.0	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.8	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.0	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.4	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.0	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.4	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0030018	Z disc(GO:0030018)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.5	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.0	GO:0030990	intraciliary transport particle(GO:0030990)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.7	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.4	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.4	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.8	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.5	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.5	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.9	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.9	GO:0005112	Notch binding(GO:0005112)
0.1	0.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.4	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.5	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.6	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.4	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.6	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	1.0	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.8	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.3	GO:0043559	insulin binding(GO:0043559)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.2	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	0.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.3	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.6	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.1	GO:0045159	myosin II binding(GO:0045159)
0.1	0.7	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.3	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.5	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.9	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.5	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.5	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.5	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.5	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.4	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.7	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	1.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.4	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	1.5	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.4	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.5	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.2	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.3	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0030547	receptor inhibitor activity(GO:0030547)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.0	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	2.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	ST ADRENERGIC	Adrenergic Pathway
0.0	0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.8	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.0	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.6	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.7	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.2	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling

Results for EGR1_EGR4

Z-value: 2.83

Motif logo

Transcription factors associated with EGR1_EGR4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the EGR1_EGR4 motif across conditions

Conditions sorted by the z-value of the EGR1_EGR4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: