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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for EGR3_EGR2

Z-value: 1.34

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
EGR3
ENSG00000179388.8 early growth response 3
EGR2
ENSG00000122877.9 early growth response 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_64586125_64586276EGR272730.209296-0.742.2e-02Click!
chr10_64612517_64612668EGR2336650.171609-0.732.5e-02Click!
chr10_64577192_64577553EGR212460.474352-0.684.3e-02Click!
chr10_64610890_64611041EGR2320380.174430-0.655.7e-02Click!
chr10_64577644_64577796EGR212070.486599-0.618.2e-02Click!
chr8_22561380_22561809EGR3107790.132013-0.891.4e-03Click!
chr8_22552857_22553008EGR321170.218138-0.872.4e-03Click!
chr8_22575948_22576819EGR3255680.121945-0.844.8e-03Click!
chr8_22571215_22571366EGR3204750.126033-0.844.8e-03Click!
chr8_22571028_22571179EGR3202880.126164-0.835.8e-03Click!

Activity of the EGR3_EGR2 motif across conditions

Conditions sorted by the z-value of the EGR3_EGR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_113437546_113438608 0.97 NEUROG2
 neurogenin 2
 749
 0.58
chr13_27540158_27540309 0.87 USP12-AS1
 USP12 antisense RNA 1
 196759
 0.02
chr4_3709772_3710024 0.86 ADRA2C
 adrenoceptor alpha 2C
 58177
 0.14
chr16_88518586_88519370 0.84 ZFPM1
 zinc finger protein, FOG family member 1
 747
 0.63
chr20_34129990_34130743 0.80 ERGIC3
 ERGIC and golgi 3
 487
 0.7
chr14_34161217_34161368 0.74 NPAS3
 neuronal PAS domain protein 3
 43155
 0.21
chr10_127931048_127931232 0.74 ENSG00000222740
 .
 96989
 0.08
chr8_127570759_127570910 0.71 FAM84B
 family with sequence similarity 84, member B
 196
 0.83
chr1_220863452_220864325 0.70 C1orf115
 chromosome 1 open reading frame 115
 701
 0.71
chr4_81228983_81229134 0.68 C4orf22
 chromosome 4 open reading frame 22
 27816
 0.2
chr11_70963344_70963766 0.68 SHANK2
 SH3 and multiple ankyrin repeat domains 2
 68
 0.98
chr21_47239386_47239537 0.67 AL592528.1
16872
 0.19
chr17_45365957_45366108 0.67 RP11-290H9.4
17019
 0.13
chr14_104182645_104183196 0.59 ZFYVE21
 zinc finger, FYVE domain containing 21
 775
 0.34
chr12_26151630_26151781 0.59 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 3768
 0.29
chr18_77265355_77265646 0.56 AC018445.1
 Uncharacterized protein
 10557
 0.27
chr10_128075122_128075273 0.54 ADAM12
 ADAM metallopeptidase domain 12
 1827
 0.47
chr1_9189681_9190164 0.53 GPR157
 G protein-coupled receptor 157
 693
 0.66
chr6_131924415_131924566 0.52 MED23
 mediator complex subunit 23
 6845
 0.18
chr2_239149590_239149855 0.51 HES6
 hes family bHLH transcription factor 6
 419
 0.75
chr12_132379887_132380588 0.50 ULK1
 unc-51 like autophagy activating kinase 1
 1041
 0.51
chr18_21762368_21762519 0.47 OSBPL1A
 oxysterol binding protein-like 1A
 2644
 0.2
chr5_153990433_153990710 0.47 ENSG00000264760
 .
 14939
 0.21
chr1_161575871_161576361 0.46 FCGR2C
 Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
 10773
 0.12
chr16_88448984_88449499 0.45 ZNF469
 zinc finger protein 469
 44638
 0.14
chr10_72647360_72647920 0.44 PCBD1
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
 901
 0.61
chr3_11195342_11196026 0.44 HRH1
 histamine receptor H1
 530
 0.86
chr20_42143574_42144320 0.43 L3MBTL1
 l(3)mbt-like 1 (Drosophila)
 781
 0.59
chr6_149667254_149667417 0.43 TAB2
 TGF-beta activated kinase 1/MAP3K7 binding protein 2
 23709
 0.17
chr20_17816311_17816543 0.43 ENSG00000221220
 .
 6800
 0.24
chr1_1631163_1631760 0.43 SLC35E2B
 solute carrier family 35, member E2B
 7294
 0.11
chr6_170361246_170361397 0.42 RP11-302L19.1
116420
 0.06
chr13_106204547_106204698 0.42 DAOA-AS1
 DAOA antisense RNA 1
 46592
 0.19
chr11_417004_417487 0.42 SIGIRR
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
 80
 0.94
chr3_46924910_46925242 0.42 PTH1R
 parathyroid hormone 1 receptor
 229
 0.87
chr9_139636321_139636758 0.42 LCN10
 lipocalin 10
 816
 0.35
chr4_85419435_85420104 0.41 NKX6-1
 NK6 homeobox 1
 166
 0.97
chr10_105253662_105254118 0.41 NEURL1
 neuralized E3 ubiquitin protein ligase 1
 154
 0.92
chr5_139283800_139284387 0.41 NRG2
 neuregulin 2
 111
 0.97
chr17_36031578_36031729 0.41 DDX52
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
 28160
 0.14
chr21_43299631_43300178 0.41 PRDM15
 PR domain containing 15
 313
 0.82
chr19_17716649_17717262 0.40 CTD-3149D2.3
7576
 0.15
chr12_49739380_49740121 0.40 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
 950
 0.41
chr20_37079281_37079432 0.40 ENSG00000199266
 .
 1343
 0.24
chr11_111217873_111218024 0.40 ENSG00000264032
 .
 534
 0.72
chr19_47524229_47524951 0.40 NPAS1
 neuronal PAS domain protein 1
 447
 0.8
chr1_38596872_38597023 0.39 ENSG00000265596
 .
 42044
 0.15
chr16_86261645_86261796 0.39 ENSG00000199949
 .
 47409
 0.19
chr9_139462117_139462567 0.39 RP11-611D20.2
18760
 0.09
chr3_183947384_183948074 0.39 VWA5B2
 von Willebrand factor A domain containing 5B2
 488
 0.65
chr11_64059326_64060001 0.39 KCNK4
 potassium channel, subfamily K, member 4
 181
 0.83
chr19_18722693_18723176 0.39 TMEM59L
 transmembrane protein 59-like
 748
 0.45
chr7_129419053_129419592 0.39 ENSG00000207691
 .
 4468
 0.17
chr11_69209589_69209740 0.39 MYEOV
 myeloma overexpressed
 148039
 0.04
chr22_30675082_30675729 0.39 GATSL3
 GATS protein-like 3
 10191
 0.09
chr3_134034709_134034891 0.38 AMOTL2
 angiomotin like 2
 55954
 0.13
chr17_79070617_79071314 0.38 BAIAP2
 BAI1-associated protein 2
 414
 0.74
chr6_17033705_17033856 0.37 STMND1
 stathmin domain containing 1
 68709
 0.14
chr3_47844781_47845806 0.37 DHX30
 DEAH (Asp-Glu-Ala-His) box helicase 30
 638
 0.69
chr5_178724831_178724982 0.37 ADAMTS2
 ADAM metallopeptidase with thrombospondin type 1 motif, 2
 47525
 0.17
chr15_80696331_80696627 0.36 ARNT2
 aryl-hydrocarbon receptor nuclear translocator 2
 214
 0.79
chr13_98742061_98742212 0.36 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
 52680
 0.14
chr11_68659074_68659228 0.36 MRPL21
 mitochondrial ribosomal protein L21
 12095
 0.15
chr19_16177822_16178237 0.36 TPM4
 tropomyosin 4
 198
 0.94
chr3_52039773_52040512 0.36 RPL29
 ribosomal protein L29
 10184
 0.09
chr14_103673785_103674145 0.35 ENSG00000239117
 .
 4442
 0.24
chr6_147135992_147136143 0.35 ADGB
 androglobin
 13072
 0.25
chr22_50422080_50422460 0.35 IL17REL
 interleukin 17 receptor E-like
 24851
 0.15
chr19_50355314_50356474 0.35 PTOV1-AS1
 PTOV1 antisense RNA 1
 961
 0.21
chr8_81477973_81478412 0.35 ENSG00000223327
 .
 19816
 0.2
chr6_5083119_5083270 0.35 PPP1R3G
 protein phosphatase 1, regulatory subunit 3G
 2526
 0.31
chr21_46890680_46890997 0.34 COL18A1
 collagen, type XVIII, alpha 1
 15414
 0.18
chrX_47433764_47434046 0.34 TIMP1
 TIMP metallopeptidase inhibitor 1
 7807
 0.13
chr7_128828160_128828607 0.34 SMO
 smoothened, frizzled family receptor
 330
 0.84
chr11_63378218_63378369 0.34 PLA2G16
 phospholipase A2, group XVI
 2240
 0.22
chr13_100613171_100613322 0.33 ZIC5
 Zic family member 5
 10917
 0.19
chr7_73899343_73899494 0.33 ENSG00000238391
 .
 2452
 0.31
chr11_118016566_118017132 0.33 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
 6686
 0.16
chr3_25627117_25627268 0.33 ENSG00000272166
 .
 30095
 0.18
chr19_18272446_18272908 0.33 PIK3R2
 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
 8749
 0.1
chr11_66103534_66104527 0.33 RIN1
 Ras and Rab interactor 1
 30
 0.92
chr17_36609068_36609612 0.33 ENSG00000260833
 .
 652
 0.66
chr8_102300306_102300457 0.32 ENSG00000239115
 .
 19214
 0.24
chr16_1203566_1203784 0.32 CACNA1H
 calcium channel, voltage-dependent, T type, alpha 1H subunit
 63
 0.95
chr2_106481904_106482055 0.32 AC009505.2
8346
 0.25
chr8_140716343_140716851 0.32 KCNK9
 potassium channel, subfamily K, member 9
 1298
 0.63
chr17_32907854_32908260 0.32 TMEM132E
 transmembrane protein 132E
 289
 0.89
chr1_197924747_197924898 0.32 LHX9
 LIM homeobox 9
 38293
 0.19
chr4_1003833_1004600 0.32 FGFRL1
 fibroblast growth factor receptor-like 1
 449
 0.75
chr19_8672060_8672211 0.32 ADAMTS10
 ADAM metallopeptidase with thrombospondin type 1 motif, 10
 1048
 0.45
chrX_3181986_3182137 0.31 CXorf28
 chromosome X open reading frame 28
 7800
 0.28
chr17_38500621_38501691 0.31 RARA
 retinoic acid receptor, alpha
 337
 0.77
chr17_7746157_7747127 0.31 KDM6B
 lysine (K)-specific demethylase 6B
 1591
 0.22
chr10_112543415_112543566 0.31 ENSG00000199364
 .
 22590
 0.16
chr12_88375416_88375567 0.31 C12orf50
 chromosome 12 open reading frame 50
 46249
 0.15
chr8_22026915_22027066 0.31 BMP1
 bone morphogenetic protein 1
 4190
 0.13
chr1_1014853_1015344 0.31 RNF223
 ring finger protein 223
 5411
 0.1
chr9_139223916_139224067 0.31 GPSM1
 G-protein signaling modulator 1
 2059
 0.22
chr6_108105922_108106149 0.31 SCML4
 sex comb on midleg-like 4 (Drosophila)
 12580
 0.27
chr4_111532636_111532787 0.31 PITX2
 paired-like homeodomain 2
 11496
 0.28
chr8_143695048_143695766 0.30 ARC
 activity-regulated cytoskeleton-associated protein
 1426
 0.34
chr11_12562425_12562576 0.30 PARVA
 parvin, alpha
 88218
 0.09
chr14_55574760_55575368 0.30 LGALS3
 lectin, galactoside-binding, soluble, 3
 15764
 0.2
chr17_47938739_47938890 0.30 TAC4
 tachykinin 4 (hemokinin)
 13435
 0.16
chr20_62948255_62948712 0.30 PCMTD2
 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
 51618
 0.15
chr16_1202380_1202675 0.29 CACNA1H
 calcium channel, voltage-dependent, T type, alpha 1H subunit
 714
 0.52
chr14_69727423_69728222 0.29 GALNT16
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
 814
 0.7
chr18_46356353_46356504 0.29 RP11-484L8.1
4713
 0.31
chr5_173018079_173018230 0.29 CTB-33O18.3
11502
 0.23
chr2_236516678_236516829 0.29 ENSG00000221704
 .
 36178
 0.19
chr1_42099647_42099798 0.29 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 66950
 0.12
chr12_53297687_53297917 0.29 KRT8
 keratin 8
 370
 0.82
chr17_45055986_45056489 0.29 RPRML
 reprimo-like
 377
 0.82
chr7_16737552_16737703 0.29 BZW2
 basic leucine zipper and W2 domains 2
 9477
 0.18
chr3_49004665_49004816 0.29 RP13-131K19.1
16559
 0.08
chr21_44144329_44144647 0.28 AP001627.1
17380
 0.2
chr1_203483478_203483842 0.28 OPTC
 opticin
 18562
 0.2
chr11_48190887_48191038 0.28 OR4B1
 olfactory receptor, family 4, subfamily B, member 1
 47382
 0.13
chr13_114516970_114517121 0.28 GAS6-AS1
 GAS6 antisense RNA 1
 1558
 0.42
chr10_134000631_134000857 0.28 DPYSL4
 dihydropyrimidinase-like 4
 340
 0.84
chr12_7077943_7078351 0.28 PHB2
 prohibitin 2
 1022
 0.2
chr17_72754153_72754656 0.27 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 3738
 0.12
chr8_42030567_42030894 0.27 AP3M2
 adaptor-related protein complex 3, mu 2 subunit
 5923
 0.17
chr8_93026735_93027023 0.27 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 2712
 0.37
chr14_23357394_23357589 0.27 REM2
 RAS (RAD and GEM)-like GTP binding 2
 5060
 0.09
chr12_6472663_6473337 0.27 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
 313
 0.83
chr3_50232130_50232343 0.27 GNAT1
 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
 2131
 0.19
chr13_114898126_114898522 0.27 RASA3
 RAS p21 protein activator 3
 238
 0.94
chr19_1034551_1034702 0.26 CNN2
 calponin 2
 3490
 0.09
chr1_15224545_15224696 0.26 KAZN
 kazrin, periplakin interacting protein
 26006
 0.26
chr2_38799437_38799781 0.26 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 2631
 0.31
chr21_37572717_37572868 0.26 ENSG00000265882
 .
 13344
 0.14
chr3_156534276_156534726 0.26 LEKR1
 leucine, glutamate and lysine rich 1
 9588
 0.29
chr19_10531849_10532316 0.26 PDE4A
 phosphodiesterase 4A, cAMP-specific
 751
 0.43
chr20_62589289_62589587 0.26 UCKL1
 uridine-cytidine kinase 1-like 1
 1669
 0.16
chr1_231410009_231410185 0.25 ENSG00000222407
 .
 7173
 0.17
chr17_17017881_17018380 0.25 MPRIP
 myosin phosphatase Rho interacting protein
 16850
 0.15
chr11_12424964_12425115 0.25 PARVA
 parvin, alpha
 5251
 0.27
chr13_76223017_76223168 0.25 LMO7
 LIM domain 7
 12633
 0.18
chr7_100808302_100808702 0.25 VGF
 VGF nerve growth factor inducible
 107
 0.93
chr14_105796875_105797044 0.25 PACS2
 phosphofurin acidic cluster sorting protein 2
 5803
 0.17
chr11_46354061_46354426 0.25 DGKZ
 diacylglycerol kinase, zeta
 212
 0.92
chr22_35748735_35749057 0.25 ENSG00000266320
 .
 17263
 0.15
chr1_206654151_206654302 0.24 IKBKE
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
 10388
 0.14
chr2_219696298_219696449 0.24 PRKAG3
 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
 141
 0.94
chr5_55151409_55151585 0.24 IL31RA
 interleukin 31 receptor A
 2139
 0.34
chr16_67012908_67013059 0.24 CES4A
 carboxylesterase 4A
 9509
 0.11
chr3_71127883_71128284 0.24 FOXP1
 forkhead box P1
 13165
 0.3
chr8_38261754_38262108 0.24 LETM2
 leucine zipper-EF-hand containing transmembrane protein 2
 0
 0.96
chr1_180202351_180202502 0.24 LHX4
 LIM homeobox 4
 3005
 0.29
chr12_133083658_133084311 0.24 FBRSL1
 fibrosin-like 1
 16827
 0.19
chr2_173139735_173139887 0.24 ENSG00000238572
 .
 118963
 0.05
chr1_156675699_156676565 0.24 CRABP2
 cellular retinoic acid binding protein 2
 524
 0.6
chr19_45843748_45844099 0.24 KLC3
 kinesin light chain 3
 88
 0.94
chr7_151574672_151575021 0.24 PRKAG2-AS1
 PRKAG2 antisense RNA 1
 296
 0.72
chr2_110883713_110883864 0.23 ENSG00000212091
 .
 613
 0.67
chr15_45952586_45952737 0.23 SQRDL
 sulfide quinone reductase-like (yeast)
 1382
 0.46
chr6_50818276_50818427 0.23 TFAP2B
 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
 31912
 0.25
chr1_200004031_200004580 0.23 NR5A2
 nuclear receptor subfamily 5, group A, member 2
 7294
 0.18
chr17_6679303_6679767 0.23 FBXO39
 F-box protein 39
 7
 0.97
chr6_1620291_1620740 0.23 FOXC1
 forkhead box C1
 9834
 0.3
chr12_92368232_92368383 0.23 C12orf79
 chromosome 12 open reading frame 79
 162490
 0.04
chr19_590689_590900 0.23 HCN2
 hyperpolarization activated cyclic nucleotide-gated potassium channel 2
 901
 0.37
chr10_13500720_13500871 0.23 BEND7
 BEN domain containing 7
 22278
 0.16
chr3_120170476_120170627 0.23 FSTL1
 follistatin-like 1
 451
 0.88
chr9_96720941_96721916 0.23 BARX1
 BARX homeobox 1
 3774
 0.31
chr14_73392660_73393072 0.23 DCAF4
 DDB1 and CUL4 associated factor 4
 174
 0.95
chr19_48627309_48627460 0.23 CTC-453G23.5
5689
 0.12
chr9_110925898_110926343 0.23 ENSG00000222512
 .
 195089
 0.03
chr20_31147574_31147725 0.23 RP11-410N8.3
1246
 0.42
chr21_47188043_47188194 0.23 PRED60
1887
 0.41
chr4_176333346_176333497 0.23 ENSG00000221136
 .
 60732
 0.16
chr20_34716861_34717019 0.22 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
 3574
 0.2
chr1_181074818_181075147 0.22 IER5
 immediate early response 5
 17344
 0.22
chr2_20018587_20018738 0.22 TTC32
 tetratricopeptide repeat domain 32
 82740
 0.1
chr1_206762660_206762811 0.22 EIF2D
 eukaryotic translation initiation factor 2D
 23068
 0.13
chr19_4473935_4474715 0.22 HDGFRP2
 Hepatoma-derived growth factor-related protein 2
 564
 0.54
chr9_21543413_21543564 0.22 MIR31HG
 MIR31 host gene (non-protein coding)
 16180
 0.15
chr11_14051655_14051806 0.22 ENSG00000212365
 .
 104802
 0.07
chr1_244080456_244080691 0.21 AKT3
 v-akt murine thymoma viral oncogene homolog 3
 66192
 0.12
chr12_57674022_57674790 0.21 R3HDM2
 R3H domain containing 2
 3371
 0.16
chr18_14974636_14974787 0.21 ENSG00000266544
 .
 115466
 0.06
chr6_41456635_41457010 0.21 RP11-328M4.2
56990
 0.1
chr1_94080800_94080951 0.21 BCAR3
 breast cancer anti-estrogen resistance 3
 1221
 0.52
chr11_110634298_110634449 0.21 ARHGAP20
 Rho GTPase activating protein 20
 50461
 0.19
chr2_219748132_219748430 0.21 WNT10A
 wingless-type MMTV integration site family, member 10A
 1398
 0.3
chr5_132166329_132166761 0.21 SHROOM1
 shroom family member 1
 45
 0.96
chr14_103242729_103243285 0.21 TRAF3
 TNF receptor-associated factor 3
 806
 0.63
chr9_14322498_14322883 0.21 NFIB
 nuclear factor I/B
 353
 0.91
chr19_4718186_4718464 0.21 DPP9
 dipeptidyl-peptidase 9
 425
 0.75
chr17_76919622_76920491 0.21 TIMP2
 TIMP metallopeptidase inhibitor 2
 1413
 0.35
chr5_76925321_76925875 0.21 WDR41
 WD repeat domain 41
 9162
 0.23
chr1_246149947_246150098 0.21 RP11-83A16.1
46831
 0.18
chr1_856648_857113 0.21 SAMD11
 sterile alpha motif domain containing 11
 3380
 0.14
chr6_146136305_146136901 0.21 RP11-545I5.3
169
 0.88
chr19_40972580_40972926 0.21 SPTBN4
 spectrin, beta, non-erythrocytic 4
 373
 0.7
chr2_109790847_109791252 0.21 ENSG00000264934
 .
 33005
 0.2
chr5_110584557_110584708 0.21 AC010468.2
21155
 0.19
chr18_55094933_55095260 0.21 ONECUT2
 one cut homeobox 2
 7821
 0.21
chr12_122158077_122158228 0.20 TMEM120B
 transmembrane protein 120B
 7451
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0021508 floor plate formation(GO:0021508)
0.1 0.2 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.1 0.2 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0060539 diaphragm development(GO:0060539)
0.1 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.5 GO:0010894 negative regulation of steroid biosynthetic process(GO:0010894)
0.0 0.1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0044252 negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0030432 peristalsis(GO:0030432)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0090102 cochlea development(GO:0090102)
0.0 0.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.1 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.2 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.1 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.0 GO:0090189 regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0048265 response to pain(GO:0048265)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0048935 peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0080031 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.4 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination