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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EGR3_EGR2

Z-value: 1.34

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Transcription factors associated with EGR3_EGR2

Gene Symbol	Gene ID	Gene Info
EGR3 Ensembl NCBI GeneCards UniProt	ENSG00000179388.8	EGR3
EGR2 Ensembl NCBI GeneCards UniProt	ENSG00000122877.9	EGR2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
EGR2	chr10_64586125_64586276	7273	0.209296	-0.74	2.2e-02	Click!
EGR2	chr10_64612517_64612668	33665	0.171609	-0.73	2.5e-02	Click!
EGR2	chr10_64577192_64577553	1246	0.474352	-0.68	4.3e-02	Click!
EGR2	chr10_64610890_64611041	32038	0.174430	-0.65	5.7e-02	Click!
EGR2	chr10_64577644_64577796	1207	0.486599	-0.61	8.2e-02	Click!
EGR3	chr8_22561380_22561809	10779	0.132013	-0.89	1.4e-03	Click!
EGR3	chr8_22552857_22553008	2117	0.218138	-0.87	2.4e-03	Click!
EGR3	chr8_22575948_22576819	25568	0.121945	-0.84	4.8e-03	Click!
EGR3	chr8_22571215_22571366	20475	0.126033	-0.84	4.8e-03	Click!
EGR3	chr8_22571028_22571179	20288	0.126164	-0.83	5.8e-03	Click!

Activity of the EGR3_EGR2 motif across conditions

Conditions sorted by the z-value of the EGR3_EGR2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_113437546_113438608	0.97	NEUROG2	neurogenin 2	749	0.58
chr13_27540158_27540309	0.87	USP12-AS1	USP12 antisense RNA 1	196759	0.02
chr4_3709772_3710024	0.86	ADRA2C	adrenoceptor alpha 2C	58177	0.14
chr16_88518586_88519370	0.84	ZFPM1	zinc finger protein, FOG family member 1	747	0.63
chr20_34129990_34130743	0.80	ERGIC3	ERGIC and golgi 3	487	0.7
chr14_34161217_34161368	0.74	NPAS3	neuronal PAS domain protein 3	43155	0.21
chr10_127931048_127931232	0.74	ENSG00000222740	.	96989	0.08
chr8_127570759_127570910	0.71	FAM84B	family with sequence similarity 84, member B	196	0.83
chr1_220863452_220864325	0.70	C1orf115	chromosome 1 open reading frame 115	701	0.71
chr4_81228983_81229134	0.68	C4orf22	chromosome 4 open reading frame 22	27816	0.2
chr11_70963344_70963766	0.68	SHANK2	SH3 and multiple ankyrin repeat domains 2	68	0.98
chr21_47239386_47239537	0.67	AL592528.1		16872	0.19
chr17_45365957_45366108	0.67	RP11-290H9.4		17019	0.13
chr14_104182645_104183196	0.59	ZFYVE21	zinc finger, FYVE domain containing 21	775	0.34
chr12_26151630_26151781	0.59	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	3768	0.29
chr18_77265355_77265646	0.56	AC018445.1	Uncharacterized protein	10557	0.27
chr10_128075122_128075273	0.54	ADAM12	ADAM metallopeptidase domain 12	1827	0.47
chr1_9189681_9190164	0.53	GPR157	G protein-coupled receptor 157	693	0.66
chr6_131924415_131924566	0.52	MED23	mediator complex subunit 23	6845	0.18
chr2_239149590_239149855	0.51	HES6	hes family bHLH transcription factor 6	419	0.75
chr12_132379887_132380588	0.50	ULK1	unc-51 like autophagy activating kinase 1	1041	0.51
chr18_21762368_21762519	0.47	OSBPL1A	oxysterol binding protein-like 1A	2644	0.2
chr5_153990433_153990710	0.47	ENSG00000264760	.	14939	0.21
chr1_161575871_161576361	0.46	FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	10773	0.12
chr16_88448984_88449499	0.45	ZNF469	zinc finger protein 469	44638	0.14
chr10_72647360_72647920	0.44	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	901	0.61
chr3_11195342_11196026	0.44	HRH1	histamine receptor H1	530	0.86
chr20_42143574_42144320	0.43	L3MBTL1	l(3)mbt-like 1 (Drosophila)	781	0.59
chr6_149667254_149667417	0.43	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	23709	0.17
chr20_17816311_17816543	0.43	ENSG00000221220	.	6800	0.24
chr1_1631163_1631760	0.43	SLC35E2B	solute carrier family 35, member E2B	7294	0.11
chr6_170361246_170361397	0.42	RP11-302L19.1		116420	0.06
chr13_106204547_106204698	0.42	DAOA-AS1	DAOA antisense RNA 1	46592	0.19
chr11_417004_417487	0.42	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	80	0.94
chr3_46924910_46925242	0.42	PTH1R	parathyroid hormone 1 receptor	229	0.87
chr9_139636321_139636758	0.42	LCN10	lipocalin 10	816	0.35
chr4_85419435_85420104	0.41	NKX6-1	NK6 homeobox 1	166	0.97
chr10_105253662_105254118	0.41	NEURL1	neuralized E3 ubiquitin protein ligase 1	154	0.92
chr5_139283800_139284387	0.41	NRG2	neuregulin 2	111	0.97
chr17_36031578_36031729	0.41	DDX52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	28160	0.14
chr21_43299631_43300178	0.41	PRDM15	PR domain containing 15	313	0.82
chr19_17716649_17717262	0.40	CTD-3149D2.3		7576	0.15
chr12_49739380_49740121	0.40	DNAJC22	DnaJ (Hsp40) homolog, subfamily C, member 22	950	0.41
chr20_37079281_37079432	0.40	ENSG00000199266	.	1343	0.24
chr11_111217873_111218024	0.40	ENSG00000264032	.	534	0.72
chr19_47524229_47524951	0.40	NPAS1	neuronal PAS domain protein 1	447	0.8
chr1_38596872_38597023	0.39	ENSG00000265596	.	42044	0.15
chr16_86261645_86261796	0.39	ENSG00000199949	.	47409	0.19
chr9_139462117_139462567	0.39	RP11-611D20.2		18760	0.09
chr3_183947384_183948074	0.39	VWA5B2	von Willebrand factor A domain containing 5B2	488	0.65
chr11_64059326_64060001	0.39	KCNK4	potassium channel, subfamily K, member 4	181	0.83
chr19_18722693_18723176	0.39	TMEM59L	transmembrane protein 59-like	748	0.45
chr7_129419053_129419592	0.39	ENSG00000207691	.	4468	0.17
chr11_69209589_69209740	0.39	MYEOV	myeloma overexpressed	148039	0.04
chr22_30675082_30675729	0.39	GATSL3	GATS protein-like 3	10191	0.09
chr3_134034709_134034891	0.38	AMOTL2	angiomotin like 2	55954	0.13
chr17_79070617_79071314	0.38	BAIAP2	BAI1-associated protein 2	414	0.74
chr6_17033705_17033856	0.37	STMND1	stathmin domain containing 1	68709	0.14
chr3_47844781_47845806	0.37	DHX30	DEAH (Asp-Glu-Ala-His) box helicase 30	638	0.69
chr5_178724831_178724982	0.37	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	47525	0.17
chr15_80696331_80696627	0.36	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	214	0.79
chr13_98742061_98742212	0.36	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	52680	0.14
chr11_68659074_68659228	0.36	MRPL21	mitochondrial ribosomal protein L21	12095	0.15
chr19_16177822_16178237	0.36	TPM4	tropomyosin 4	198	0.94
chr3_52039773_52040512	0.36	RPL29	ribosomal protein L29	10184	0.09
chr14_103673785_103674145	0.35	ENSG00000239117	.	4442	0.24
chr6_147135992_147136143	0.35	ADGB	androglobin	13072	0.25
chr22_50422080_50422460	0.35	IL17REL	interleukin 17 receptor E-like	24851	0.15
chr19_50355314_50356474	0.35	PTOV1-AS1	PTOV1 antisense RNA 1	961	0.21
chr8_81477973_81478412	0.35	ENSG00000223327	.	19816	0.2
chr6_5083119_5083270	0.35	PPP1R3G	protein phosphatase 1, regulatory subunit 3G	2526	0.31
chr21_46890680_46890997	0.34	COL18A1	collagen, type XVIII, alpha 1	15414	0.18
chrX_47433764_47434046	0.34	TIMP1	TIMP metallopeptidase inhibitor 1	7807	0.13
chr7_128828160_128828607	0.34	SMO	smoothened, frizzled family receptor	330	0.84
chr11_63378218_63378369	0.34	PLA2G16	phospholipase A2, group XVI	2240	0.22
chr13_100613171_100613322	0.33	ZIC5	Zic family member 5	10917	0.19
chr7_73899343_73899494	0.33	ENSG00000238391	.	2452	0.31
chr11_118016566_118017132	0.33	SCN4B	sodium channel, voltage-gated, type IV, beta subunit	6686	0.16
chr3_25627117_25627268	0.33	ENSG00000272166	.	30095	0.18
chr19_18272446_18272908	0.33	PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	8749	0.1
chr11_66103534_66104527	0.33	RIN1	Ras and Rab interactor 1	30	0.92
chr17_36609068_36609612	0.33	ENSG00000260833	.	652	0.66
chr8_102300306_102300457	0.32	ENSG00000239115	.	19214	0.24
chr16_1203566_1203784	0.32	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	63	0.95
chr2_106481904_106482055	0.32	AC009505.2		8346	0.25
chr8_140716343_140716851	0.32	KCNK9	potassium channel, subfamily K, member 9	1298	0.63
chr17_32907854_32908260	0.32	TMEM132E	transmembrane protein 132E	289	0.89
chr1_197924747_197924898	0.32	LHX9	LIM homeobox 9	38293	0.19
chr4_1003833_1004600	0.32	FGFRL1	fibroblast growth factor receptor-like 1	449	0.75
chr19_8672060_8672211	0.32	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	1048	0.45
chrX_3181986_3182137	0.31	CXorf28	chromosome X open reading frame 28	7800	0.28
chr17_38500621_38501691	0.31	RARA	retinoic acid receptor, alpha	337	0.77
chr17_7746157_7747127	0.31	KDM6B	lysine (K)-specific demethylase 6B	1591	0.22
chr10_112543415_112543566	0.31	ENSG00000199364	.	22590	0.16
chr12_88375416_88375567	0.31	C12orf50	chromosome 12 open reading frame 50	46249	0.15
chr8_22026915_22027066	0.31	BMP1	bone morphogenetic protein 1	4190	0.13
chr1_1014853_1015344	0.31	RNF223	ring finger protein 223	5411	0.1
chr9_139223916_139224067	0.31	GPSM1	G-protein signaling modulator 1	2059	0.22
chr6_108105922_108106149	0.31	SCML4	sex comb on midleg-like 4 (Drosophila)	12580	0.27
chr4_111532636_111532787	0.31	PITX2	paired-like homeodomain 2	11496	0.28
chr8_143695048_143695766	0.30	ARC	activity-regulated cytoskeleton-associated protein	1426	0.34
chr11_12562425_12562576	0.30	PARVA	parvin, alpha	88218	0.09
chr14_55574760_55575368	0.30	LGALS3	lectin, galactoside-binding, soluble, 3	15764	0.2
chr17_47938739_47938890	0.30	TAC4	tachykinin 4 (hemokinin)	13435	0.16
chr20_62948255_62948712	0.30	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	51618	0.15
chr16_1202380_1202675	0.29	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	714	0.52
chr14_69727423_69728222	0.29	GALNT16	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16	814	0.7
chr18_46356353_46356504	0.29	RP11-484L8.1		4713	0.31
chr5_173018079_173018230	0.29	CTB-33O18.3		11502	0.23
chr2_236516678_236516829	0.29	ENSG00000221704	.	36178	0.19
chr1_42099647_42099798	0.29	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	66950	0.12
chr12_53297687_53297917	0.29	KRT8	keratin 8	370	0.82
chr17_45055986_45056489	0.29	RPRML	reprimo-like	377	0.82
chr7_16737552_16737703	0.29	BZW2	basic leucine zipper and W2 domains 2	9477	0.18
chr3_49004665_49004816	0.29	RP13-131K19.1		16559	0.08
chr21_44144329_44144647	0.28	AP001627.1		17380	0.2
chr1_203483478_203483842	0.28	OPTC	opticin	18562	0.2
chr11_48190887_48191038	0.28	OR4B1	olfactory receptor, family 4, subfamily B, member 1	47382	0.13
chr13_114516970_114517121	0.28	GAS6-AS1	GAS6 antisense RNA 1	1558	0.42
chr10_134000631_134000857	0.28	DPYSL4	dihydropyrimidinase-like 4	340	0.84
chr12_7077943_7078351	0.28	PHB2	prohibitin 2	1022	0.2
chr17_72754153_72754656	0.27	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	3738	0.12
chr8_42030567_42030894	0.27	AP3M2	adaptor-related protein complex 3, mu 2 subunit	5923	0.17
chr8_93026735_93027023	0.27	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	2712	0.37
chr14_23357394_23357589	0.27	REM2	RAS (RAD and GEM)-like GTP binding 2	5060	0.09
chr12_6472663_6473337	0.27	SCNN1A	sodium channel, non-voltage-gated 1 alpha subunit	313	0.83
chr3_50232130_50232343	0.27	GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	2131	0.19
chr13_114898126_114898522	0.27	RASA3	RAS p21 protein activator 3	238	0.94
chr19_1034551_1034702	0.26	CNN2	calponin 2	3490	0.09
chr1_15224545_15224696	0.26	KAZN	kazrin, periplakin interacting protein	26006	0.26
chr2_38799437_38799781	0.26	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	2631	0.31
chr21_37572717_37572868	0.26	ENSG00000265882	.	13344	0.14
chr3_156534276_156534726	0.26	LEKR1	leucine, glutamate and lysine rich 1	9588	0.29
chr19_10531849_10532316	0.26	PDE4A	phosphodiesterase 4A, cAMP-specific	751	0.43
chr20_62589289_62589587	0.26	UCKL1	uridine-cytidine kinase 1-like 1	1669	0.16
chr1_231410009_231410185	0.25	ENSG00000222407	.	7173	0.17
chr17_17017881_17018380	0.25	MPRIP	myosin phosphatase Rho interacting protein	16850	0.15
chr11_12424964_12425115	0.25	PARVA	parvin, alpha	5251	0.27
chr13_76223017_76223168	0.25	LMO7	LIM domain 7	12633	0.18
chr7_100808302_100808702	0.25	VGF	VGF nerve growth factor inducible	107	0.93
chr14_105796875_105797044	0.25	PACS2	phosphofurin acidic cluster sorting protein 2	5803	0.17
chr11_46354061_46354426	0.25	DGKZ	diacylglycerol kinase, zeta	212	0.92
chr22_35748735_35749057	0.25	ENSG00000266320	.	17263	0.15
chr1_206654151_206654302	0.24	IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	10388	0.14
chr2_219696298_219696449	0.24	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	141	0.94
chr5_55151409_55151585	0.24	IL31RA	interleukin 31 receptor A	2139	0.34
chr16_67012908_67013059	0.24	CES4A	carboxylesterase 4A	9509	0.11
chr3_71127883_71128284	0.24	FOXP1	forkhead box P1	13165	0.3
chr8_38261754_38262108	0.24	LETM2	leucine zipper-EF-hand containing transmembrane protein 2	0	0.96
chr1_180202351_180202502	0.24	LHX4	LIM homeobox 4	3005	0.29
chr12_133083658_133084311	0.24	FBRSL1	fibrosin-like 1	16827	0.19
chr2_173139735_173139887	0.24	ENSG00000238572	.	118963	0.05
chr1_156675699_156676565	0.24	CRABP2	cellular retinoic acid binding protein 2	524	0.6
chr19_45843748_45844099	0.24	KLC3	kinesin light chain 3	88	0.94
chr7_151574672_151575021	0.24	PRKAG2-AS1	PRKAG2 antisense RNA 1	296	0.72
chr2_110883713_110883864	0.23	ENSG00000212091	.	613	0.67
chr15_45952586_45952737	0.23	SQRDL	sulfide quinone reductase-like (yeast)	1382	0.46
chr6_50818276_50818427	0.23	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	31912	0.25
chr1_200004031_200004580	0.23	NR5A2	nuclear receptor subfamily 5, group A, member 2	7294	0.18
chr17_6679303_6679767	0.23	FBXO39	F-box protein 39	7	0.97
chr6_1620291_1620740	0.23	FOXC1	forkhead box C1	9834	0.3
chr12_92368232_92368383	0.23	C12orf79	chromosome 12 open reading frame 79	162490	0.04
chr19_590689_590900	0.23	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	901	0.37
chr10_13500720_13500871	0.23	BEND7	BEN domain containing 7	22278	0.16
chr3_120170476_120170627	0.23	FSTL1	follistatin-like 1	451	0.88
chr9_96720941_96721916	0.23	BARX1	BARX homeobox 1	3774	0.31
chr14_73392660_73393072	0.23	DCAF4	DDB1 and CUL4 associated factor 4	174	0.95
chr19_48627309_48627460	0.23	CTC-453G23.5		5689	0.12
chr9_110925898_110926343	0.23	ENSG00000222512	.	195089	0.03
chr20_31147574_31147725	0.23	RP11-410N8.3		1246	0.42
chr21_47188043_47188194	0.23	PRED60		1887	0.41
chr4_176333346_176333497	0.23	ENSG00000221136	.	60732	0.16
chr20_34716861_34717019	0.22	EPB41L1	erythrocyte membrane protein band 4.1-like 1	3574	0.2
chr1_181074818_181075147	0.22	IER5	immediate early response 5	17344	0.22
chr2_20018587_20018738	0.22	TTC32	tetratricopeptide repeat domain 32	82740	0.1
chr1_206762660_206762811	0.22	EIF2D	eukaryotic translation initiation factor 2D	23068	0.13
chr19_4473935_4474715	0.22	HDGFRP2	Hepatoma-derived growth factor-related protein 2	564	0.54
chr9_21543413_21543564	0.22	MIR31HG	MIR31 host gene (non-protein coding)	16180	0.15
chr11_14051655_14051806	0.22	ENSG00000212365	.	104802	0.07
chr1_244080456_244080691	0.21	AKT3	v-akt murine thymoma viral oncogene homolog 3	66192	0.12
chr12_57674022_57674790	0.21	R3HDM2	R3H domain containing 2	3371	0.16
chr18_14974636_14974787	0.21	ENSG00000266544	.	115466	0.06
chr6_41456635_41457010	0.21	RP11-328M4.2		56990	0.1
chr1_94080800_94080951	0.21	BCAR3	breast cancer anti-estrogen resistance 3	1221	0.52
chr11_110634298_110634449	0.21	ARHGAP20	Rho GTPase activating protein 20	50461	0.19
chr2_219748132_219748430	0.21	WNT10A	wingless-type MMTV integration site family, member 10A	1398	0.3
chr5_132166329_132166761	0.21	SHROOM1	shroom family member 1	45	0.96
chr14_103242729_103243285	0.21	TRAF3	TNF receptor-associated factor 3	806	0.63
chr9_14322498_14322883	0.21	NFIB	nuclear factor I/B	353	0.91
chr19_4718186_4718464	0.21	DPP9	dipeptidyl-peptidase 9	425	0.75
chr17_76919622_76920491	0.21	TIMP2	TIMP metallopeptidase inhibitor 2	1413	0.35
chr5_76925321_76925875	0.21	WDR41	WD repeat domain 41	9162	0.23
chr1_246149947_246150098	0.21	RP11-83A16.1		46831	0.18
chr1_856648_857113	0.21	SAMD11	sterile alpha motif domain containing 11	3380	0.14
chr6_146136305_146136901	0.21	RP11-545I5.3		169	0.88
chr19_40972580_40972926	0.21	SPTBN4	spectrin, beta, non-erythrocytic 4	373	0.7
chr2_109790847_109791252	0.21	ENSG00000264934	.	33005	0.2
chr5_110584557_110584708	0.21	AC010468.2		21155	0.19
chr18_55094933_55095260	0.21	ONECUT2	one cut homeobox 2	7821	0.21
chr12_122158077_122158228	0.20	TMEM120B	transmembrane protein 120B	7451	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.4	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.6	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.1	0.3	GO:0021508	floor plate formation(GO:0021508)
0.1	0.2	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.1	0.2	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.3	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.5	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.0	0.1	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.2	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.3	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:0044252	negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.2	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.2	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.2	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.0	0.1	GO:0002090	regulation of receptor internalization(GO:0002090)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.0	GO:0060433	bronchus development(GO:0060433)
0.0	0.0	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0090189	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.1	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.0	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0048935	peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.5	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.4	GO:0031526	brush border membrane(GO:0031526)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.4	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.0	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.8	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.3	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.3	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.4	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.0	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination