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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for EN1_ESX1_GBX1

Z-value: 0.64

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Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol	Gene ID	Gene Info
EN1 Ensembl NCBI GeneCards UniProt	ENSG00000163064.6	engrailed homeobox 1
ESX1 Ensembl NCBI GeneCards UniProt	ENSG00000123576.5	ESX homeobox 1
GBX1 Ensembl NCBI GeneCards UniProt	ENSG00000164900.4	gastrulation brain homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_119604302_119604453	EN1	877	0.722417	0.74	2.4e-02	Click!
chr2_119613220_119613380	EN1	8046	0.284480	0.67	5.0e-02	Click!
chr2_119601751_119601902	EN1	3428	0.351300	-0.64	6.5e-02	Click!
chr2_119636557_119636708	EN1	31378	0.200440	0.62	7.2e-02	Click!
chr2_119428510_119428661	EN1	176669	0.033053	-0.62	7.7e-02	Click!
chrX_103527312_103527463	ESX1	27773	0.222884	0.50	1.7e-01	Click!
chrX_103498038_103498189	ESX1	1501	0.502858	-0.39	3.0e-01	Click!
chrX_103515680_103515910	ESX1	16181	0.250052	0.34	3.7e-01	Click!
chrX_103499710_103499861	ESX1	171	0.967774	0.25	5.1e-01	Click!
chrX_103500366_103500538	ESX1	838	0.711682	-0.23	5.5e-01	Click!
chr7_150865341_150865492	GBX1	781	0.486875	0.60	8.9e-02	Click!
chr7_150864318_150864541	GBX1	206	0.891771	0.58	1.0e-01	Click!
chr7_150865062_150865339	GBX1	565	0.623681	0.55	1.2e-01	Click!
chr7_150869600_150869767	GBX1	5048	0.118828	0.21	5.9e-01	Click!
chr7_150865554_150865723	GBX1	1003	0.385837	0.20	6.1e-01	Click!

Activity of the EN1_ESX1_GBX1 motif across conditions

Conditions sorted by the z-value of the EN1_ESX1_GBX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_3859909_3860060	0.38	LRRN1	leucine rich repeat neuronal 1	18863	0.29
chr1_225610187_225610435	0.36	LBR	lamin B receptor	5288	0.2
chr10_130706677_130706967	0.36	MGMT	O-6-methylguanine-DNA methyltransferase	558626	0.0
chr13_53584885_53585127	0.35	OLFM4	olfactomedin 4	17888	0.28
chr6_142498285_142498436	0.34	VTA1	vesicle (multivesicular body) trafficking 1	29962	0.18
chr3_11317381_11317532	0.33	ATG7	autophagy related 7	1449	0.5
chr8_27223358_27224128	0.32	PTK2B	protein tyrosine kinase 2 beta	14425	0.22
chr12_104940888_104941108	0.32	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	41628	0.17
chr3_122048704_122048855	0.31	CSTA	cystatin A (stefin A)	4670	0.19
chr21_16064096_16064532	0.31	AF165138.7	Protein LOC388813	33172	0.21
chr1_200121942_200122869	0.31	ENSG00000221403	.	8443	0.27
chr6_37665777_37665940	0.30	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	92	0.98
chr12_72078949_72079234	0.29	TMEM19	transmembrane protein 19	776	0.62
chr2_175207474_175207756	0.29	AC018470.1	Uncharacterized protein FLJ46347	5464	0.18
chr20_43671143_43671294	0.29	ENSG00000252021	.	38229	0.11
chr7_130696111_130696721	0.29	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	27548	0.2
chr9_100937607_100937767	0.28	CORO2A	coronin, actin binding protein, 2A	2521	0.31
chr2_226984282_226984472	0.28	ENSG00000263363	.	539132	0.0
chrX_70292512_70292905	0.28	SNX12	sorting nexin 12	4435	0.14
chr8_48237150_48237301	0.28	SPIDR	scaffolding protein involved in DNA repair	63668	0.14
chr6_46758113_46758264	0.28	MEP1A	meprin A, alpha (PABA peptide hydrolase)	2939	0.26
chr16_30188682_30188851	0.27	CORO1A	coronin, actin binding protein, 1A	5382	0.09
chr12_120113093_120113244	0.27	PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	3119	0.22
chr9_137251018_137251277	0.27	ENSG00000263897	.	20110	0.22
chr15_76933945_76934096	0.27	ENSG00000266449	.	55032	0.15
chr11_64629664_64630187	0.27	EHD1	EH-domain containing 1	13213	0.09
chr1_87082986_87083335	0.27	ENSG00000221702	.	11120	0.18
chr3_151793463_151793614	0.27	RP11-454C18.2		147575	0.04
chr4_146102106_146102613	0.26	OTUD4	OTU domain containing 4	1046	0.59
chr14_25458841_25458992	0.26	STXBP6	syntaxin binding protein 6 (amisyn)	20930	0.27
chr4_88817062_88817672	0.26	MEPE	matrix extracellular phosphoglycoprotein	63228	0.1
chr13_50144464_50144942	0.26	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	3244	0.28
chr17_18204377_18204528	0.26	TOP3A	topoisomerase (DNA) III alpha	1531	0.27
chr9_112239573_112239724	0.26	PTPN3	protein tyrosine phosphatase, non-receptor type 3	20938	0.21
chr14_54913534_54913685	0.26	CNIH1	cornichon family AMPA receptor auxiliary protein 1	5460	0.23
chr14_73928086_73928502	0.26	ENSG00000251393	.	835	0.54
chr12_104528955_104529393	0.25	NFYB	nuclear transcription factor Y, beta	2621	0.26
chr5_157226577_157226728	0.25	CLINT1	clathrin interactor 1	6312	0.18
chr9_33976084_33976235	0.25	UBAP2	ubiquitin associated protein 2	12882	0.13
chr6_10085176_10085327	0.25	OFCC1	orofacial cleft 1 candidate 1	29756	0.25
chr14_56672356_56672619	0.25	PELI2	pellino E3 ubiquitin protein ligase family member 2	86660	0.1
chr5_148365723_148365874	0.25	RP11-44B19.1		15895	0.18
chr12_117959445_117959596	0.25	RP11-227B21.2		68703	0.13
chr2_143918611_143918880	0.25	RP11-190J23.1		10996	0.25
chr11_112193182_112193453	0.24	ENSG00000206772	.	30068	0.14
chr11_77113729_77113923	0.24	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	9123	0.24
chr4_14996539_14996690	0.24	CPEB2	cytoplasmic polyadenylation element binding protein 2	7684	0.31
chr16_24741783_24741934	0.24	TNRC6A	trinucleotide repeat containing 6A	824	0.73
chr5_17413551_17413702	0.24	ENSG00000201715	.	67901	0.13
chr18_21068750_21068901	0.24	RIOK3	RIO kinase 3	11673	0.16
chr2_11345179_11345416	0.24	ENSG00000207267	.	28817	0.16
chr10_93684234_93684699	0.24	BTAF1	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa	940	0.57
chr1_200987046_200987749	0.24	KIF21B	kinesin family member 21B	5139	0.21
chr13_41574006_41574157	0.24	ELF1	E74-like factor 1 (ets domain transcription factor)	17663	0.19
chr6_83901990_83902379	0.24	PGM3	phosphoglucomutase 3	766	0.48
chr14_103246832_103247104	0.24	TRAF3	TNF receptor-associated factor 3	3013	0.25
chr1_25887771_25887922	0.24	LDLRAP1	low density lipoprotein receptor adaptor protein 1	17775	0.19
chr14_92973076_92973375	0.24	RIN3	Ras and Rab interactor 3	6893	0.29
chr13_52134820_52134971	0.23	ENSG00000252141	.	4653	0.14
chr10_28664504_28664655	0.23	ENSG00000222666	.	32601	0.16
chr2_43402387_43402951	0.23	ZFP36L2	ZFP36 ring finger protein-like 2	51079	0.14
chr14_102277041_102277192	0.23	CTD-2017C7.2		458	0.64
chr10_98301601_98301752	0.23	TLL2	tolloid-like 2	28008	0.18
chr3_190262015_190262166	0.23	IL1RAP	interleukin 1 receptor accessory protein	19145	0.25
chr2_64355977_64356407	0.23	AC074289.1		14181	0.22
chr14_93512017_93512168	0.23	ITPK1	inositol-tetrakisphosphate 1-kinase	20611	0.19
chr7_102665979_102666130	0.23	RP11-645N11.3		4497	0.17
chr2_162095070_162095308	0.23	TANK	TRAF family member-associated NFKB activator	7492	0.21
chr2_63926133_63926284	0.22	ENSG00000221085	.	3539	0.34
chr17_4297572_4297951	0.22	UBE2G1	ubiquitin-conjugating enzyme E2G 1	27838	0.13
chr2_172008488_172008813	0.22	ENSG00000238567	.	5810	0.25
chr3_15372664_15372990	0.22	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	1240	0.39
chr4_159814009_159814160	0.22	FNIP2	folliculin interacting protein 2	60852	0.12
chr10_78066550_78066701	0.22	C10orf11	chromosome 10 open reading frame 11	11467	0.23
chr3_195949731_195949882	0.22	SLC51A	solute carrier family 51, alpha subunit	5043	0.14
chr2_224627856_224628007	0.22	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	74270	0.12
chr9_131127238_131127389	0.22	URM1	ubiquitin related modifier 1	6285	0.1
chr19_43853396_43853679	0.22	CD177	CD177 molecule	4288	0.2
chr16_68784328_68784479	0.22	ENSG00000200558	.	8020	0.16
chr4_16273062_16273213	0.22	TAPT1-AS1	TAPT1 antisense RNA 1 (head to head)	44469	0.15
chr12_95196881_95197032	0.22	ENSG00000208038	.	31218	0.23
chr1_21296214_21296365	0.22	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	3240	0.28
chr9_86321400_86321693	0.22	RP11-522I20.3		963	0.39
chr6_71378349_71379129	0.22	SMAP1	small ArfGAP 1	1118	0.64
chr11_118889854_118890205	0.22	ENSG00000266398	.	375	0.42
chr19_956957_957108	0.22	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	24523	0.07
chr7_116867645_116867796	0.22	AC002465.2		73195	0.1
chr8_38264429_38264741	0.22	RP11-350N15.6		1675	0.23
chr2_118859435_118859586	0.22	INSIG2	insulin induced gene 2	13460	0.23
chr12_89551166_89551590	0.22	ENSG00000238302	.	124684	0.06
chr9_123975852_123976003	0.21	GSN	gelsolin	5849	0.16
chr9_92032244_92032395	0.21	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1429	0.51
chr11_112832281_112832432	0.21	NCAM1	neural cell adhesion molecule 1	154	0.72
chr3_177432439_177432616	0.21	ENSG00000200288	.	90330	0.1
chr6_109286669_109286820	0.21	RP11-787I22.3		32941	0.15
chr12_123552434_123552585	0.21	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	8133	0.18
chr22_49992417_49992568	0.21	RP1-29C18.8		16872	0.16
chr22_43421246_43421514	0.21	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	10229	0.18
chr8_27131884_27132088	0.21	STMN4	stathmin-like 4	16049	0.18
chr4_88929574_88929774	0.21	PKD2	polycystic kidney disease 2 (autosomal dominant)	854	0.61
chr1_17350232_17350454	0.21	ATP13A2	ATPase type 13A2	11920	0.16
chr1_111994170_111994475	0.21	ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	2216	0.14
chrX_96479090_96479241	0.21	ENSG00000265260	.	116880	0.07
chr9_13278613_13278764	0.21	RP11-272P10.2		498	0.61
chr10_119787120_119787271	0.21	RP11-354M20.3		10165	0.2
chr4_15008135_15008306	0.21	CPEB2	cytoplasmic polyadenylation element binding protein 2	2660	0.4
chr1_31986275_31986426	0.21	ENSG00000206981	.	15825	0.16
chr2_99954705_99955291	0.21	EIF5B	eukaryotic translation initiation factor 5B	1182	0.4
chr19_58311508_58311659	0.21	ZNF552	zinc finger protein 552	13189	0.09
chr10_106094941_106095155	0.21	ITPRIP	inositol 1,4,5-trisphosphate receptor interacting protein	1385	0.33
chr1_159053605_159053756	0.21	AIM2	absent in melanoma 2	6989	0.19
chr17_30340874_30341075	0.21	LRRC37B	leucine rich repeat containing 37B	5967	0.2
chr20_34233623_34233774	0.21	ENSG00000252549	.	1654	0.21
chr11_58941542_58941693	0.20	DTX4	deltex homolog 4 (Drosophila)	1652	0.33
chr22_41251648_41251915	0.20	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	1179	0.3
chr8_6722304_6722455	0.20	DEFB1	defensin, beta 1	13165	0.19
chr2_145826193_145826344	0.20	ENSG00000253036	.	266370	0.02
chr9_71633765_71634208	0.20	PRKACG	protein kinase, cAMP-dependent, catalytic, gamma	4947	0.24
chr6_143645822_143645973	0.20	AL031320.1		113678	0.05
chr3_171486556_171486707	0.20	PLD1	phospholipase D1, phosphatidylcholine-specific	2518	0.32
chr4_55685762_55685928	0.20	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	161760	0.04
chr20_31238150_31238301	0.20	RP11-410N8.4		48786	0.11
chr1_109836886_109837045	0.20	PSRC1	proline/serine-rich coiled-coil 1	11157	0.15
chr4_105888170_105888391	0.20	ENSG00000251906	.	7539	0.31
chr17_64457835_64457986	0.20	RP11-4F22.2		44938	0.17
chr14_50317979_50318647	0.20	NEMF	nuclear export mediator factor	1185	0.29
chr11_20135030_20135181	0.20	NAV2-AS1	NAV2 antisense RNA 1	7073	0.24
chr2_152510948_152511099	0.20	NEB	nebulin	70890	0.13
chr7_21004042_21004193	0.20	SP8	Sp8 transcription factor	177612	0.03
chr11_45952993_45953260	0.20	GYLTL1B	glycosyltransferase-like 1B	3539	0.16
chr5_73839209_73839360	0.20	HEXB	hexosaminidase B (beta polypeptide)	96564	0.07
chr5_168305212_168305363	0.20	ENSG00000202345	.	86784	0.08
chr2_102615790_102616089	0.20	IL1R2	interleukin 1 receptor, type II	482	0.86
chr2_65008994_65009145	0.20	ENSG00000253082	.	5831	0.22
chr20_293073_293224	0.20	RP5-1103G7.4		12730	0.11
chr2_231110516_231110667	0.20	SP140	SP140 nuclear body protein	20112	0.18
chr16_50776974_50777435	0.20	RP11-327F22.1		478	0.4
chr2_113544940_113545312	0.20	IL1A	interleukin 1, alpha	2959	0.23
chr10_62954984_62955245	0.20	RHOBTB1	Rho-related BTB domain containing 1	193916	0.03
chr10_118225483_118225634	0.20	PNLIPRP3	pancreatic lipase-related protein 3	38179	0.16
chr22_18254916_18255090	0.19	BID	BH3 interacting domain death agonist	1779	0.34
chr6_144018421_144018671	0.19	PHACTR2	phosphatase and actin regulator 2	19341	0.25
chr1_246233834_246234131	0.19	RP11-83A16.1		37129	0.17
chr7_115994446_115994930	0.19	ENSG00000216076	.	8690	0.21
chr4_140310025_140310176	0.19	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	2778	0.23
chr3_148691598_148691749	0.19	RP11-680B3.2		13774	0.19
chr1_66733315_66733555	0.19	PDE4B	phosphodiesterase 4B, cAMP-specific	10105	0.3
chr1_10851874_10852025	0.19	CASZ1	castor zinc finger 1	4756	0.28
chr8_119113924_119114075	0.19	EXT1	exostosin glycosyltransferase 1	8654	0.33
chr9_80410813_80410964	0.19	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	27027	0.25
chr14_68064458_68064609	0.19	PIGH	phosphatidylinositol glycan anchor biosynthesis, class H	2316	0.2
chr14_93365196_93365347	0.19	CHGA	chromogranin A (parathyroid secretory protein 1)	24154	0.22
chr1_226084453_226084634	0.19	LEFTY1	left-right determination factor 1	7697	0.12
chr21_19188629_19188846	0.19	C21orf91	chromosome 21 open reading frame 91	2599	0.3
chr6_133081661_133081812	0.19	VNN2	vanin 2	2589	0.18
chr5_150828832_150828983	0.19	SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1	1577	0.38
chr9_4137653_4137928	0.19	GLIS3	GLIS family zinc finger 3	7403	0.28
chr5_125758880_125759032	0.19	GRAMD3	GRAM domain containing 3	87	0.98
chr2_27273137_27273288	0.19	AGBL5-AS1	AGBL5 antisense RNA 1	80	0.87
chr2_9140202_9140353	0.19	MBOAT2	membrane bound O-acyltransferase domain containing 2	3517	0.3
chr6_76011105_76011372	0.19	TMEM30A	transmembrane protein 30A	16554	0.18
chr4_68748084_68748235	0.19	TMPRSS11D	transmembrane protease, serine 11D	1540	0.47
chr6_105220514_105220665	0.19	HACE1	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1	4377	0.25
chr14_69196211_69196400	0.19	ENSG00000207089	.	6440	0.23
chr12_65369994_65370192	0.19	ENSG00000221564	.	37290	0.18
chr12_64798932_64799366	0.19	XPOT	exportin, tRNA	323	0.88
chr16_15405386_15405537	0.19	NPIPA5	nuclear pore complex interacting protein family, member A5	58465	0.1
chrX_154473029_154473180	0.19	RAB39B	RAB39B, member RAS oncogene family	20770	0.15
chr21_16063526_16063677	0.19	AF165138.7	Protein LOC388813	32459	0.22
chr1_96418282_96418433	0.18	RP11-147C23.1	Uncharacterized protein	39188	0.2
chr10_11628107_11628334	0.18	USP6NL	USP6 N-terminal like	12380	0.23
chr7_107567137_107567288	0.18	CTB-13F3.1		15349	0.18
chr2_180868101_180868324	0.18	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	3568	0.34
chr20_50384471_50384622	0.18	ATP9A	ATPase, class II, type 9A	321	0.92
chr1_151830153_151830304	0.18	THEM5	thioesterase superfamily member 5	4055	0.11
chr2_26226210_26226361	0.18	KIF3C	kinesin family member 3C	20667	0.16
chr18_72443447_72443598	0.18	ZNF407	zinc finger protein 407	100546	0.08
chrX_38728176_38728358	0.18	MID1IP1-AS1	MID1IP1 antisense RNA 1	65131	0.13
chr8_127567681_127568033	0.18	RP11-103H7.5		1284	0.38
chr12_80333289_80333440	0.18	PPP1R12A	protein phosphatase 1, regulatory subunit 12A	4124	0.23
chr2_100297232_100297383	0.18	AFF3	AF4/FMR2 family, member 3	102475	0.08
chr1_203338435_203338586	0.18	FMOD	fibromodulin	17893	0.19
chr2_102914112_102914534	0.18	IL1RL1	interleukin 1 receptor-like 1	13639	0.19
chr11_46581607_46581927	0.18	AMBRA1	autophagy/beclin-1 regulator 1	31147	0.15
chr9_120466316_120466467	0.18	TLR4	toll-like receptor 4	219	0.94
chr2_70271915_70272125	0.18	PCBP1-AS1	PCBP1 antisense RNA 1	8897	0.17
chr21_35898997_35899524	0.18	RCAN1	regulator of calcineurin 1	1	0.98
chr14_45627397_45627548	0.18	FANCM	Fanconi anemia, complementation group M	3510	0.21
chr17_29817845_29818325	0.18	RAB11FIP4	RAB11 family interacting protein 4 (class II)	2959	0.19
chr1_197730766_197730996	0.18	RP11-448G4.4		4432	0.25
chr5_164785761_164785912	0.18	ENSG00000252794	.	250610	0.02
chr20_46411011_46411162	0.18	SULF2	sulfatase 2	3147	0.3
chr8_97873595_97873746	0.18	CPQ	carboxypeptidase Q	100202	0.08
chr16_73092870_73093114	0.18	ZFHX3	zinc finger homeobox 3	605	0.79
chr7_21405981_21406526	0.18	ENSG00000195024	.	14728	0.23
chrX_55741083_55741234	0.18	RRAGB	Ras-related GTP binding B	3014	0.33
chr8_80696428_80696687	0.18	ENSG00000238884	.	15873	0.22
chrX_106928490_106928775	0.18	TSC22D3	TSC22 domain family, member 3	30999	0.18
chr10_79302559_79302710	0.18	ENSG00000199592	.	44173	0.18
chr15_50648645_50649024	0.18	ENSG00000244879	.	166	0.9

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.3	GO:0052305	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.2	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.2	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.7	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0060535	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.2	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.4	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.2	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.3	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.3	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.3	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.2	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	1.1	GO:0061025	membrane fusion(GO:0061025)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.1	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.5	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0051769	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.2	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0034033	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.1	GO:1903901	negative regulation of viral process(GO:0048525) negative regulation of viral life cycle(GO:1903901)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.1	GO:0071221	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.1	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.1	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.3	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.3	GO:0009251	glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:2001235	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.2	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0060487	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.2	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.1	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0033483	gas homeostasis(GO:0033483)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0010894	negative regulation of steroid biosynthetic process(GO:0010894)
0.0	0.3	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.3	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.2	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.2	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.2	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0019400	alditol metabolic process(GO:0019400)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.4	GO:0000724	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:2001233	regulation of release of cytochrome c from mitochondria(GO:0090199) regulation of apoptotic signaling pathway(GO:2001233)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.0	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.4	GO:0043039	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.2	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.0	GO:0016571	histone methylation(GO:0016571)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.1	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.0	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0000303	response to superoxide(GO:0000303)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0030992	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.3	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.5	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.0	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.9	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.1	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.2	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.4	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.4	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.4	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.4	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0016408	C-acyltransferase activity(GO:0016408)
0.0	0.0	GO:0008443	6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.5	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.3	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.6	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.0	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.8	PID FOXO PATHWAY	FoxO family signaling
0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.4	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	PID IGF1 PATHWAY	IGF1 pathway
0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	PID AURORA A PATHWAY	Aurora A signaling
0.3	ST GAQ PATHWAY	G alpha q Pathway
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	1.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.5	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha

Results for EN1_ESX1_GBX1

Z-value: 0.64

Motif logo

Transcription factors associated with EN1_ESX1_GBX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the EN1_ESX1_GBX1 motif across conditions

Conditions sorted by the z-value of the EN1_ESX1_GBX1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: