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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EP300

Z-value: 1.58

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Transcription factors associated with EP300

Gene Symbol	Gene ID	Gene Info
EP300 Ensembl NCBI GeneCards UniProt	ENSG00000100393.9	EP300

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
EP300	chr22_41486861_41487035	842	0.442239	-0.54	1.3e-01	Click!
EP300	chr22_41484824_41484975	2891	0.168443	-0.33	3.8e-01	Click!
EP300	chr22_41486558_41486753	1135	0.342792	-0.11	7.8e-01	Click!

Activity of the EP300 motif across conditions

Conditions sorted by the z-value of the EP300 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_10425893_10426393	0.60	ENSG00000264030	.	5386	0.18
chr3_135789780_135789936	0.57	RP11-305O4.3		16897	0.24
chr20_56574359_56574689	0.54	ENSG00000221451	.	23450	0.2
chr2_45926277_45926449	0.52	U51244.2		23748	0.22
chr10_81163756_81163932	0.51	RP11-342M3.5		21760	0.18
chr6_91004978_91005129	0.50	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	1408	0.5
chr17_76677287_76677438	0.49	ENSG00000252391	.	15517	0.19
chr6_136333041_136333452	0.48	ENSG00000222121	.	34205	0.18
chr13_33837466_33837749	0.47	ENSG00000236581	.	7909	0.23
chr4_5039625_5039803	0.47	STK32B	serine/threonine kinase 32B	13455	0.23
chr9_38038631_38039019	0.47	SHB	Src homology 2 domain containing adaptor protein B	30383	0.2
chr2_9372792_9372943	0.47	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	25973	0.24
chr12_1905679_1905979	0.46	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	15057	0.2
chr19_35629782_35630121	0.46	FXYD1	FXYD domain containing ion transport regulator 1	71	0.94
chr22_46402793_46403252	0.45	WNT7B	wingless-type MMTV integration site family, member 7B	30013	0.1
chr11_130397678_130397978	0.45	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15	78959	0.1
chr7_98717947_98718887	0.45	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	23225	0.2
chr1_151519925_151520338	0.44	ENSG00000207606	.	1859	0.2
chr1_27425346_27425645	0.43	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	55478	0.1
chr2_223907840_223908197	0.42	KCNE4	potassium voltage-gated channel, Isk-related family, member 4	8514	0.28
chr9_137366473_137366866	0.42	RXRA	retinoid X receptor, alpha	68241	0.11
chr1_31870163_31870721	0.42	SERINC2	serine incorporator 2	11970	0.15
chr22_28176285_28176436	0.42	MN1	meningioma (disrupted in balanced translocation) 1	21126	0.23
chr5_172378668_172378890	0.41	RPL26L1	ribosomal protein L26-like 1	6953	0.16
chr3_9390957_9391108	0.41	THUMPD3	THUMP domain containing 3	13494	0.15
chr11_47995337_47995576	0.40	PTPRJ	protein tyrosine phosphatase, receptor type, J	6657	0.23
chr11_122582204_122582355	0.40	ENSG00000239079	.	14740	0.23
chr5_179344255_179344770	0.40	TBC1D9B	TBC1 domain family, member 9B (with GRAM domain)	9653	0.15
chr1_40358181_40358689	0.40	RP1-118J21.5		4982	0.14
chr6_106607187_106607338	0.39	RP1-134E15.3		59247	0.12
chr17_76370784_76371498	0.39	PGS1	phosphatidylglycerophosphate synthase 1	3580	0.16
chr6_56776311_56776462	0.39	ENSG00000200224	.	34142	0.15
chr7_72974638_72974971	0.39	BCL7B	B-cell CLL/lymphoma 7B	2472	0.22
chr16_54482153_54482558	0.39	ENSG00000264079	.	100953	0.08
chr5_172330219_172330468	0.39	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	1877	0.34
chr9_112886766_112887049	0.38	AKAP2	A kinase (PRKA) anchor protein 2	874	0.72
chr1_29575738_29576111	0.38	ENSG00000221550	.	4271	0.18
chr12_69735025_69735271	0.37	LYZ	lysozyme	6973	0.18
chr14_90377788_90378051	0.37	EFCAB11	EF-hand calcium binding domain 11	42948	0.16
chr11_109966413_109966654	0.37	ZC3H12C	zinc finger CCCH-type containing 12C	2446	0.45
chr17_40476887_40477238	0.37	STAT5A	signal transducer and activator of transcription 5A	18874	0.12
chr11_32334737_32335009	0.36	WT1	Wilms tumor 1	87288	0.09
chr17_48288085_48288285	0.36	COL1A1	collagen, type I, alpha 1	9192	0.12
chr17_41613704_41613971	0.36	ETV4	ets variant 4	6035	0.15
chr16_85404884_85405267	0.36	RP11-680G10.1	Uncharacterized protein	14006	0.23
chr8_37660040_37660273	0.35	GPR124	G protein-coupled receptor 124	5382	0.16
chr3_48601792_48601997	0.35	UCN2	urocortin 2	688	0.49
chr2_128404783_128404934	0.35	GPR17	G protein-coupled receptor 17	834	0.4
chr8_67978067_67978286	0.35	COPS5	COP9 signalosome subunit 5	998	0.4
chr10_123908613_123908797	0.35	TACC2	transforming, acidic coiled-coil containing protein 2	14236	0.27
chr3_153850737_153851019	0.35	ARHGEF26	Rho guanine nucleotide exchange factor (GEF) 26	11649	0.22
chr12_124864748_124865018	0.35	NCOR2	nuclear receptor corepressor 2	8487	0.28
chr5_136408537_136408688	0.35	ENSG00000222285	.	103617	0.08
chr6_111873197_111873348	0.34	TRAF3IP2-AS1	TRAF3IP2 antisense RNA 1	13182	0.18
chr19_13143361_13143794	0.34	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	7766	0.1
chr4_142274474_142274770	0.34	ENSG00000238695	.	55590	0.16
chr20_45903718_45903972	0.34	ZMYND8	zinc finger, MYND-type containing 8	23799	0.14
chr14_69510813_69511070	0.34	ACTN1-AS1	ACTN1 antisense RNA 1	64183	0.11
chr1_116088166_116088317	0.33	ENSG00000265534	.	59969	0.11
chr10_126745830_126745994	0.33	ENSG00000264572	.	24473	0.19
chr2_9252566_9252858	0.33	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	94182	0.08
chr1_178511388_178511762	0.33	C1orf220	chromosome 1 open reading frame 220	312	0.54
chr5_150860485_150860639	0.33	ENSG00000200227	.	3424	0.21
chr2_20624136_20624633	0.33	RHOB	ras homolog family member B	22451	0.16
chr8_22037074_22037225	0.33	BMP1	bone morphogenetic protein 1	14349	0.1
chr6_150177550_150177701	0.33	RP11-350J20.12		4027	0.14
chr10_105409169_105409599	0.33	SH3PXD2A	SH3 and PX domains 2A	12078	0.17
chr14_77466848_77467305	0.32	IRF2BPL	interferon regulatory factor 2 binding protein-like	27958	0.16
chr21_36626320_36626700	0.32	RUNX1	runt-related transcription factor 1	204869	0.03
chr20_48920943_48921193	0.32	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	113692	0.05
chr7_151574506_151574657	0.32	PRKAG2-AS1	PRKAG2 antisense RNA 1	31	0.85
chr5_66602255_66602461	0.32	CD180	CD180 molecule	109731	0.07
chr14_59074133_59074284	0.32	DACT1	dishevelled-binding antagonist of beta-catenin 1	26578	0.22
chr12_65960194_65960365	0.32	MSRB3	methionine sulfoxide reductase B3	239624	0.02
chr1_42248602_42248753	0.32	ENSG00000264896	.	23865	0.25
chr3_185484667_185484947	0.32	ENSG00000265470	.	885	0.65
chr2_218793055_218793347	0.32	TNS1	tensin 1	8269	0.24
chr13_98019941_98020221	0.31	ENSG00000202290	.	4726	0.26
chr4_54343359_54343510	0.31	LNX1-AS1	LNX1 antisense RNA 1	19133	0.21
chr10_104389775_104390433	0.31	TRIM8	tripartite motif containing 8	14149	0.16
chr8_13017195_13017346	0.31	ENSG00000200630	.	417	0.88
chr17_26698665_26699277	0.31	SARM1	sterile alpha and TIR motif containing 1	288	0.7
chr3_185348019_185348218	0.31	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2	16975	0.22
chr3_149093349_149093607	0.31	TM4SF1	transmembrane 4 L six family member 1	21	0.97
chr9_89338062_89338213	0.31	GAS1	growth arrest-specific 1	223967	0.02
chr15_74343218_74343437	0.31	ENSG00000244612	.	21712	0.12
chr22_31687874_31688321	0.31	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	284	0.57
chr10_61889951_61890102	0.31	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	9132	0.25
chr10_90411662_90411938	0.31	LIPF	lipase, gastric	12398	0.19
chr5_148441355_148441506	0.31	ENSG00000207714	.	542	0.63
chr12_26941848_26941999	0.31	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	43791	0.17
chr12_52596098_52596249	0.31	KRT80	keratin 80	10389	0.12
chr22_44321304_44321455	0.31	PNPLA3	patatin-like phospholipase domain containing 3	1696	0.32
chr17_79486044_79486605	0.30	RP13-766D20.2		258	0.83
chr1_26187643_26188072	0.30	RP1-125I3.2		1753	0.17
chr14_96561569_96561720	0.30	C14orf132	chromosome 14 open reading frame 132	5048	0.23
chr6_80255763_80256050	0.30	LCA5	Leber congenital amaurosis 5	8731	0.3
chr1_201645041_201645675	0.30	RP11-25B7.1		2086	0.26
chr5_133576165_133576389	0.30	PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	14444	0.15
chr8_103588249_103588656	0.30	ODF1	outer dense fiber of sperm tails 1	15762	0.19
chr3_50204088_50204384	0.30	ENSG00000207922	.	6523	0.12
chr2_217950201_217950452	0.30	ENSG00000251849	.	90895	0.08
chr12_53465850_53466141	0.30	SPRYD3	SPRY domain containing 3	7166	0.11
chr9_140162312_140162640	0.30	TOR4A	torsin family 4, member A	9725	0.07
chr4_144304158_144304414	0.30	GAB1	GRB2-associated binding protein 1	1188	0.55
chr3_129318244_129318493	0.30	PLXND1	plexin D1	7293	0.17
chr6_35453605_35453891	0.29	TEAD3	TEA domain family member 3	5849	0.17
chr16_85404269_85404483	0.29	RP11-680G10.1	Uncharacterized protein	13307	0.23
chr6_109062843_109063094	0.29	FOXO3	forkhead box O3	85419	0.09
chr9_113779231_113779588	0.29	LPAR1	lysophosphatidic acid receptor 1	17663	0.24
chr6_106995891_106996258	0.29	AIM1	absent in melanoma 1	7045	0.21
chr12_286084_286235	0.29	RP11-598F7.5		10672	0.13
chr4_40992453_40992714	0.29	ENSG00000201736	.	412	0.87
chr15_74881081_74881232	0.29	CLK3	CDC-like kinase 3	19557	0.14
chr3_111622183_111622334	0.29	PHLDB2	pleckstrin homology-like domain, family B, member 2	8199	0.25
chr3_155105502_155105653	0.29	ENSG00000272096	.	50035	0.15
chr22_21795497_21795765	0.29	HIC2	hypermethylated in cancer 2	1118	0.38
chr11_114163796_114163947	0.29	NNMT	nicotinamide N-methyltransferase	2676	0.32
chr10_76683925_76684076	0.29	KAT6B	K(lysine) acetyltransferase 6B	85542	0.08
chr18_53994440_53994591	0.29	ENSG00000201816	.	247690	0.02
chr1_201682575_201682726	0.29	ENSG00000264802	.	5986	0.14
chr22_24533322_24533473	0.29	CABIN1	calcineurin binding protein 1	18409	0.16
chr14_70487599_70487750	0.29	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3	59223	0.14
chr8_118993019_118993290	0.29	EXT1	exostosin glycosyltransferase 1	129499	0.06
chr10_77189776_77190205	0.29	RP11-399K21.10		1356	0.46
chr14_65706212_65706363	0.29	ENSG00000266740	.	95614	0.07
chr14_77533175_77533326	0.29	CIPC	CLOCK-interacting pacemaker	31190	0.13
chr7_73891950_73892160	0.29	ENSG00000238391	.	9815	0.21
chr1_78005634_78006073	0.29	AK5	adenylate kinase 5	8061	0.24
chr7_2147015_2147173	0.29	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	249	0.95
chr8_57788733_57788884	0.29	ENSG00000206975	.	40835	0.21
chr17_55967739_55968110	0.29	CUEDC1	CUE domain containing 1	2125	0.29
chr13_24185129_24185409	0.29	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	31750	0.22
chr17_72746217_72746759	0.29	MIR3615	microRNA 3615	1437	0.2
chr14_68830721_68830872	0.29	RAD51B	RAD51 paralog B	47431	0.18
chr19_45359914_45360258	0.29	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	10303	0.11
chr14_69015594_69016105	0.28	CTD-2325P2.4		79313	0.1
chr18_54877274_54877586	0.28	BOD1L2	biorientation of chromosomes in cell division 1-like 2	63137	0.12
chr19_6077071_6077284	0.28	CTC-232P5.3		9213	0.15
chr22_50542699_50542954	0.28	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)	14141	0.12
chr9_132333116_132333436	0.28	RP11-492E3.2		4412	0.17
chr16_55530572_55531230	0.28	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	8327	0.22
chr3_167780653_167780804	0.28	GOLIM4	golgi integral membrane protein 4	32404	0.24
chr20_43348798_43349109	0.28	WISP2	WNT1 inducible signaling pathway protein 2	5067	0.15
chr12_53301791_53301942	0.28	KRT8	keratin 8	1022	0.45
chr2_54468176_54468327	0.28	TSPYL6	TSPY-like 6	15158	0.24
chr19_6092846_6093008	0.28	CTB-66B24.1		16406	0.13
chr12_104802583_104802734	0.28	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	48088	0.15
chr12_65889411_65889562	0.28	MSRB3	methionine sulfoxide reductase B3	168831	0.03
chr8_103344010_103344161	0.28	UBR5	ubiquitin protein ligase E3 component n-recognin 5	26600	0.17
chr11_47437227_47437644	0.28	SLC39A13	solute carrier family 39 (zinc transporter), member 13	5799	0.09
chr12_3228682_3229088	0.28	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	30078	0.18
chr2_9779111_9779391	0.28	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta	8108	0.21
chr19_13166675_13166854	0.28	AC007787.2		15424	0.1
chr17_39934382_39934550	0.28	JUP	junction plakoglobin	5945	0.11
chr2_218828722_218828873	0.28	AC010136.2		14633	0.19
chr9_91144416_91144843	0.28	NXNL2	nucleoredoxin-like 2	5387	0.32
chr17_75449983_75450281	0.28	SEPT9	septin 9	22	0.97
chr21_40298103_40298304	0.28	ENSG00000272015	.	31494	0.23
chr1_181122041_181122219	0.28	IER5	immediate early response 5	64492	0.12
chr20_35476556_35476707	0.28	SOGA1	suppressor of glucose, autophagy associated 1	11645	0.16
chr19_55658239_55658390	0.28	TNNT1	troponin T type 1 (skeletal, slow)	3	0.95
chr1_113265986_113266348	0.27	FAM19A3	family with sequence similarity 19 (chemokine (C-C motif)-like), member A3	2968	0.15
chr18_55455792_55455943	0.27	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	14460	0.21
chr10_88160229_88160748	0.27	GRID1	glutamate receptor, ionotropic, delta 1	34253	0.17
chr12_2903497_2903902	0.27	FKBP4	FK506 binding protein 4, 59kDa	420	0.75
chr2_220138676_220138827	0.27	TUBA4A	tubulin, alpha 4a	3847	0.09
chr5_122206435_122206586	0.27	SNX24	sorting nexin 24	25189	0.17
chr11_66310128_66310279	0.27	ZDHHC24	zinc finger, DHHC-type containing 24	3503	0.12
chr3_156534966_156535117	0.27	LEKR1	leucine, glutamate and lysine rich 1	9048	0.29
chr2_202746465_202746662	0.27	ENSG00000221374	.	40711	0.12
chr4_160322851_160323002	0.27	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	51546	0.16
chr4_124400718_124400869	0.27	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	79670	0.12
chr2_218800803_218801077	0.27	TNS1	tensin 1	945	0.63
chr18_67958073_67958262	0.27	SOCS6	suppressor of cytokine signaling 6	2030	0.39
chr7_535817_536099	0.27	PDGFA	platelet-derived growth factor alpha polypeptide	22187	0.19
chr3_9129924_9130198	0.27	SRGAP3-AS1	SRGAP3 antisense RNA 1	74254	0.09
chr7_134938990_134939625	0.27	STRA8	stimulated by retinoic acid 8	22576	0.17
chr11_61485326_61485623	0.27	MYRF	myelin regulatory factor	34647	0.11
chr2_45489065_45489339	0.27	SIX2	SIX homeobox 2	252633	0.02
chr2_217204828_217205210	0.27	ENSG00000207303	.	11107	0.17
chr19_30883013_30883164	0.27	ZNF536	zinc finger protein 536	19769	0.29
chr12_124997112_124997263	0.27	NCOR2	nuclear receptor corepressor 2	5653	0.33
chr11_126252886_126253252	0.27	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	9001	0.18
chr8_110986606_110986837	0.27	KCNV1	potassium channel, subfamily V, member 1	238	0.77
chr11_2411400_2411766	0.27	CD81	CD81 molecule	258	0.86
chr16_58452611_58452869	0.27	GINS3	GINS complex subunit 3 (Psf3 homolog)	26442	0.11
chr19_6109054_6110118	0.27	CTB-66B24.1		253	0.82
chr1_24780895_24781046	0.26	NIPAL3	NIPA-like domain containing 3	1686	0.36
chr8_22458892_22459043	0.26	C8orf58	chromosome 8 open reading frame 58	342	0.76
chr10_86299589_86299740	0.26	CCSER2	coiled-coil serine-rich protein 2	114969	0.07
chr17_38227673_38228382	0.26	THRA	thyroid hormone receptor, alpha	317	0.83
chr1_33199765_33199916	0.26	KIAA1522	KIAA1522	7646	0.15
chr4_141015090_141015375	0.26	RP11-392B6.1		33937	0.2
chr6_116465835_116465986	0.26	COL10A1	collagen, type X, alpha 1	14000	0.17
chr2_106027141_106027333	0.26	FHL2	four and a half LIM domains 2	11113	0.21
chr17_40563457_40563651	0.26	PTRF	polymerase I and transcript release factor	11981	0.1
chr16_85596439_85597190	0.26	GSE1	Gse1 coiled-coil protein	48201	0.14
chr12_65888429_65888580	0.26	MSRB3	methionine sulfoxide reductase B3	167849	0.03
chr2_46564480_46564631	0.26	EPAS1	endothelial PAS domain protein 1	40014	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1	0.3	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0042684	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1	0.3	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.2	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.2	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.2	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.2	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.2	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0060433	bronchus development(GO:0060433)
0.0	0.0	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.3	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0044266	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.5	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.3	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0051709	regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.2	GO:0007625	grooming behavior(GO:0007625)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.2	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.1	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.0	GO:0071605	response to ozone(GO:0010193) monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.2	GO:0042762	regulation of sulfur metabolic process(GO:0042762)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.0	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.2	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.2	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.0	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.5	GO:0006821	chloride transport(GO:0006821)
0.0	0.0	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.0	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0044319	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.0	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.1	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0051194	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.0	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.2	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.5	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0031672	A band(GO:0031672)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	1.5	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.3	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.4	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.5	GO:0005912	adherens junction(GO:0005912)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.2	GO:0034711	inhibin binding(GO:0034711)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0046848	hydroxyapatite binding(GO:0046848)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.2	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0031014	troponin T binding(GO:0031014)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.2	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.4	GO:0016248	channel inhibitor activity(GO:0016248)
0.0	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.0	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.3	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated