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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for EPAS1_BCL3

Z-value: 3.77

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Transcription factors associated with EPAS1_BCL3

Gene Symbol	Gene ID	Gene Info
EPAS1 Ensembl NCBI GeneCards UniProt	ENSG00000116016.9	endothelial PAS domain protein 1
BCL3 Ensembl NCBI GeneCards UniProt	ENSG00000069399.8	BCL3 transcription coactivator

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_45257276_45257593	BCL3	2856	0.153436	0.57	1.1e-01	Click!
chr19_45248314_45248471	BCL3	3412	0.139265	0.53	1.5e-01	Click!
chr19_45260914_45261140	BCL3	6449	0.113039	0.51	1.6e-01	Click!
chr19_45242189_45242340	BCL3	9540	0.105825	0.42	2.6e-01	Click!
chr19_45240778_45241253	BCL3	10789	0.103796	0.39	3.0e-01	Click!
chr2_46538467_46538618	EPAS1	14001	0.258115	0.93	3.0e-04	Click!
chr2_46557321_46557472	EPAS1	32855	0.200332	0.85	4.1e-03	Click!
chr2_46563654_46563805	EPAS1	39188	0.179827	0.81	8.8e-03	Click!
chr2_46542032_46542183	EPAS1	17566	0.248085	0.81	8.8e-03	Click!
chr2_46530887_46531038	EPAS1	6421	0.287141	0.80	1.0e-02	Click!

Activity of the EPAS1_BCL3 motif across conditions

Conditions sorted by the z-value of the EPAS1_BCL3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_63638814_63639520	6.40	MARK2	MAP/microtubule affinity-regulating kinase 2	2419	0.21
chr1_32044032_32044420	3.11	TINAGL1	tubulointerstitial nephritis antigen-like 1	2087	0.23
chr11_14444247_14444712	2.08	ENSG00000251991	.	55959	0.12
chr17_36609068_36609612	1.98	ENSG00000260833	.	652	0.66
chr2_43152306_43152732	1.95	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	132787	0.05
chr5_87437759_87438959	1.93	TMEM161B	transmembrane protein 161B	78089	0.11
chr5_111077374_111077744	1.79	STARD4-AS1	STARD4 antisense RNA 1	11473	0.19
chr10_81925661_81925957	1.78	ANXA11	annexin A11	4041	0.24
chr14_73714148_73714509	1.78	ENSG00000252839	.	740	0.53
chr17_76312953_76313854	1.71	SOCS3	suppressor of cytokine signaling 3	42752	0.1
chr7_100803137_100803425	1.60	ENSG00000264425	.	527	0.61
chr7_107331221_107331712	1.60	SLC26A4	solute carrier family 26 (anion exchanger), member 4	869	0.57
chr8_108469838_108470206	1.57	ANGPT1	angiopoietin 1	37201	0.23
chr17_74542392_74542689	1.55	RP11-666A8.7		3493	0.09
chr16_80308751_80309048	1.54	DYNLRB2	dynein, light chain, roadblock-type 2	265732	0.02
chr7_29763365_29763516	1.49	ENSG00000212024	.	42996	0.15
chr5_94742657_94743120	1.47	FAM81B	family with sequence similarity 81, member B	15840	0.25
chr7_120941726_120942000	1.46	WNT16	wingless-type MMTV integration site family, member 16	23558	0.24
chr19_33764735_33765354	1.43	CTD-2540B15.11		25796	0.11
chr4_54853961_54854252	1.43	AC110792.1	HCG2027126; Uncharacterized protein	73107	0.09
chr8_93020286_93020784	1.43	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	9056	0.27
chr6_132469403_132469681	1.41	ENSG00000265669	.	33139	0.22
chr9_16986844_16987092	1.40	ENSG00000241152	.	66931	0.13
chr11_69214033_69214458	1.38	MYEOV	myeloma overexpressed	152620	0.04
chr7_101685192_101685568	1.37	CTA-357J21.1		9077	0.25
chr2_218715975_218716307	1.30	TNS1	tensin 1	9258	0.27
chr2_102686423_102686780	1.30	IL1R1	interleukin 1 receptor, type I	235	0.95
chr15_60690987_60691568	1.28	ANXA2	annexin A2	336	0.92
chr10_80916996_80917718	1.28	ZMIZ1	zinc finger, MIZ-type containing 1	88565	0.09
chr8_32093522_32093809	1.26	NRG1-IT2	NRG1 intronic transcript 2 (non-protein coding)	15221	0.2
chr7_88974_89249	1.26	FAM20C	family with sequence similarity 20, member C	103858	0.07
chr13_111696568_111696719	1.23	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	70323	0.09
chr16_11590758_11590909	1.22	CTD-3088G3.8	Protein LOC388210	5222	0.16
chr6_157470812_157471091	1.19	ARID1B	AT rich interactive domain 1B (SWI1-like)	906	0.68
chr2_74796775_74797180	1.19	LOXL3	lysyl oxidase-like 3	14160	0.09
chr15_40384302_40384677	1.19	RP11-521C20.3		3456	0.2
chr13_24185129_24185409	1.18	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	31750	0.22
chr7_22177508_22177790	1.18	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	55878	0.16
chr4_15237070_15237354	1.17	RP11-665G4.1		7628	0.29
chr11_56981252_56981403	1.17	APLNR	apelin receptor	23348	0.16
chr8_30278565_30278948	1.16	RBPMS	RNA binding protein with multiple splicing	21377	0.21
chr19_10120547_10120849	1.16	COL5A3	collagen, type V, alpha 3	449	0.68
chr22_30648620_30649241	1.15	LIF	leukemia inhibitory factor	6090	0.11
chr2_118817741_118818188	1.15	INSIG2	insulin induced gene 2	28086	0.15
chr3_196043643_196044552	1.13	TCTEX1D2	Tctex1 domain containing 2	1062	0.29
chr3_184478732_184478883	1.13	MAGEF1	melanoma antigen family F, 1	48971	0.15
chr10_116398279_116398430	1.13	ENSG00000238577	.	17915	0.22
chr20_49977899_49978050	1.12	ENSG00000263645	.	15884	0.26
chr6_134025301_134025583	1.10	RP3-323P13.2		63304	0.14
chr2_145765415_145765691	1.10	ENSG00000253036	.	327085	0.01
chr18_34915248_34915399	1.10	RP11-797E24.3		60900	0.13
chr10_4584081_4584405	1.09	ENSG00000207124	.	27099	0.26
chr18_20960634_20960918	1.09	TMEM241	transmembrane protein 241	57041	0.11
chr4_174103970_174104209	1.09	RP11-10K16.1		13286	0.18
chr10_45252007_45252274	1.08	TMEM72	transmembrane protein 72	154508	0.04
chr13_47149189_47149835	1.08	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	22117	0.25
chr11_79125207_79125358	1.08	ENSG00000266570	.	7988	0.21
chr6_90021967_90022444	1.08	GABRR2	gamma-aminobutyric acid (GABA) A receptor, rho 2	2762	0.29
chr6_36523129_36523408	1.08	STK38	serine/threonine kinase 38	8021	0.15
chr4_129491179_129491364	1.07	ENSG00000238802	.	185910	0.03
chr3_189729890_189730138	1.07	ENSG00000265045	.	101709	0.07
chr4_103609194_103609711	1.07	MANBA	mannosidase, beta A, lysosomal	72638	0.1
chr11_96059313_96059571	1.05	ENSG00000266192	.	15160	0.19
chr2_190474091_190474373	1.05	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	25748	0.18
chr13_114883288_114883480	1.05	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	9089	0.22
chr22_20776716_20777046	1.04	ENSG00000207343	.	5692	0.12
chr17_41016311_41016609	1.04	AOC4P	amine oxidase, copper containing 4, pseudogene	2836	0.12
chr13_114882980_114883149	1.03	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	8769	0.22
chr14_85883772_85884074	1.03	RP11-497E19.2	Uncharacterized protein	111020	0.07
chr2_1734793_1735092	1.02	PXDN	peroxidasin homolog (Drosophila)	13272	0.27
chr11_859519_859810	1.02	RP11-1391J7.1		131	0.9
chr1_178340233_178340977	1.01	RASAL2	RAS protein activator like 2	29999	0.22
chr1_221274663_221274840	1.00	HLX	H2.0-like homeobox	220167	0.02
chr16_81659823_81659974	0.99	CMIP	c-Maf inducing protein	19065	0.26
chr1_44513510_44513715	0.99	SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	16478	0.14
chr17_48288669_48288820	0.98	COL1A1	collagen, type I, alpha 1	9751	0.12
chr3_147660905_147661056	0.97	ENSG00000221431	.	31692	0.25
chr16_85416977_85417128	0.97	RP11-680G10.1	Uncharacterized protein	25983	0.2
chr13_36533869_36534157	0.96	DCLK1	doublecortin-like kinase 1	104234	0.08
chr13_34217166_34217453	0.95	RFC3	replication factor C (activator 1) 3, 38kDa	174877	0.03
chr2_218793437_218793804	0.95	TNS1	tensin 1	8265	0.24
chr5_39501963_39502389	0.95	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	39774	0.22
chr5_136957469_136957620	0.94	ENSG00000216009	.	25794	0.21
chr6_13733642_13733923	0.94	RANBP9	RAN binding protein 9	21986	0.19
chr21_44752301_44752505	0.93	SIK1	salt-inducible kinase 1	94605	0.08
chr1_201106487_201106638	0.93	ASCL5	achaete-scute family bHLH transcription factor 5	10250	0.16
chr12_57533530_57533928	0.93	RP11-545N8.3		7583	0.1
chr10_77229212_77229699	0.93	RP11-399K21.10		38109	0.16
chr11_14432940_14433091	0.92	RRAS2	related RAS viral (r-ras) oncogene homolog 2	46963	0.15
chr6_41025897_41026169	0.92	APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	4990	0.14
chr19_10529958_10530965	0.92	CDC37	cell division cycle 37	336	0.7
chr1_113007964_113008322	0.91	WNT2B	wingless-type MMTV integration site family, member 2B	1020	0.58
chr8_10510861_10511012	0.91	RP1L1	retinitis pigmentosa 1-like 1	1676	0.3
chr10_63698515_63698880	0.90	ENSG00000221272	.	11920	0.25
chr11_118791485_118792723	0.90	BCL9L	B-cell CLL/lymphoma 9-like	2491	0.13
chr17_1902829_1903046	0.90	CTD-2545H1.2		4029	0.12
chr6_11918444_11918726	0.90	RP11-456H18.1		73660	0.11
chr14_103242729_103243285	0.90	TRAF3	TNF receptor-associated factor 3	806	0.63
chr6_41681662_41681869	0.90	RP11-298J23.5		6369	0.13
chr10_88447809_88447960	0.89	LDB3	LIM domain binding 3	19435	0.16
chr8_108512063_108512336	0.89	ANGPT1	angiopoietin 1	1916	0.51
chr6_109441962_109442534	0.89	CEP57L1	centrosomal protein 57kDa-like 1	8259	0.21
chr2_166647514_166647908	0.88	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)	2678	0.32
chr12_20628110_20628261	0.88	RP11-284H19.1		104989	0.07
chr3_148897506_148897657	0.88	CP	ceruloplasmin (ferroxidase)	173	0.96
chr12_2041940_2042091	0.88	CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	14013	0.15
chr16_73249648_73249935	0.88	C16orf47	chromosome 16 open reading frame 47	71445	0.13
chr5_100760236_100760486	0.88	ENSG00000264318	.	157173	0.04
chr3_81789805_81790284	0.88	GBE1	glucan (1,4-alpha-), branching enzyme 1	2736	0.44
chr15_75952774_75952955	0.87	SNX33	sorting nexin 33	10767	0.09
chr8_38757081_38757383	0.87	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	1521	0.39
chr7_42030328_42030605	0.87	GLI3	GLI family zinc finger 3	236854	0.02
chr9_91566128_91566384	0.87	C9orf47	chromosome 9 open reading frame 47	39522	0.17
chr11_67146442_67146904	0.87	CLCF1	cardiotrophin-like cytokine factor 1	5025	0.08
chr19_57019660_57020194	0.87	ZNF471	zinc finger protein 471	708	0.59
chr4_3377977_3378128	0.87	RGS12	regulator of G-protein signaling 12	6446	0.24
chr17_36620428_36620685	0.87	ARHGAP23	Rho GTPase activating protein 23	6912	0.17
chr1_67043331_67043482	0.87	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1	43441	0.15
chr13_45810506_45810903	0.86	KCTD4	potassium channel tetramerization domain containing 4	35529	0.13
chr9_118970865_118971153	0.85	ENSG00000221772	.	9651	0.22
chr19_2524704_2524855	0.85	ENSG00000252962	.	21640	0.14
chr7_129933611_129933875	0.85	CPA4	carboxypeptidase A4	624	0.65
chr7_93930704_93930972	0.85	COL1A2	collagen, type I, alpha 2	93035	0.09
chr9_137539225_137539376	0.85	COL5A1-AS1	COL5A1 antisense RNA 1	5389	0.22
chr12_63097636_63097918	0.85	ENSG00000238475	.	52822	0.13
chr2_75326998_75327283	0.84	ENSG00000263909	.	9201	0.24
chr17_62051771_62052003	0.84	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	1609	0.28
chr6_149191137_149191418	0.84	RP11-162J8.2		94543	0.08
chr8_13125247_13125521	0.84	DLC1	deleted in liver cancer 1	8671	0.27
chr2_25078936_25079337	0.83	ADCY3	adenylate cyclase 3	14631	0.17
chr19_48223245_48223396	0.83	EHD2	EH-domain containing 2	6641	0.14
chr22_36748127_36749442	0.83	MYH9	myosin, heavy chain 9, non-muscle	12372	0.18
chr8_23211977_23212253	0.82	LOXL2	lysyl oxidase-like 2	16524	0.16
chr14_55243452_55244024	0.82	SAMD4A	sterile alpha motif domain containing 4A	22187	0.22
chr16_1231937_1232088	0.82	RP11-616M22.2		21836	0.09
chr15_67334683_67334893	0.82	SMAD3	SMAD family member 3	21313	0.26
chr3_107604286_107604437	0.82	BBX	bobby sox homolog (Drosophila)	86923	0.1
chr20_48190176_48190464	0.81	PTGIS	prostaglandin I2 (prostacyclin) synthase	5637	0.22
chr16_2084525_2084950	0.81	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	1465	0.15
chr20_48831535_48832061	0.81	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	24422	0.19
chr1_2209038_2209189	0.81	SKI	v-ski avian sarcoma viral oncogene homolog	48979	0.07
chr12_91290582_91290865	0.81	CCER1	coiled-coil glutamate-rich protein 1	58230	0.15
chr12_78453632_78453897	0.81	RP11-136F16.1		31753	0.23
chr19_42787089_42787782	0.81	CIC	capicua transcriptional repressor	737	0.45
chr2_121537370_121537521	0.81	GLI2	GLI family zinc finger 2	12540	0.29
chr15_92508759_92509118	0.81	SLCO3A1	solute carrier organic anion transporter family, member 3A1	111587	0.07
chrX_135259037_135259316	0.81	FHL1	four and a half LIM domains 1	7091	0.23
chr15_91094722_91095315	0.81	CRTC3	CREB regulated transcription coactivator 3	21718	0.17
chr12_26150271_26150549	0.81	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	2473	0.34
chr21_30754101_30754252	0.80	ENSG00000239171	.	7634	0.18
chr1_86072326_86072477	0.80	ENSG00000199934	.	14438	0.19
chr11_130451238_130451517	0.80	C11orf44	chromosome 11 open reading frame 44	91474	0.09
chr11_122031433_122031584	0.80	ENSG00000207994	.	8492	0.18
chr12_52596781_52596986	0.80	KRT80	keratin 80	11099	0.12
chr19_42440645_42440990	0.80	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	13571	0.12
chr16_83438196_83438487	0.80	ENSG00000222299	.	4121	0.26
chr16_55534427_55534853	0.80	LPCAT2	lysophosphatidylcholine acyltransferase 2	8270	0.22
chr6_56706459_56706925	0.80	DST	dystonin	1251	0.46
chr11_13238619_13238770	0.79	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	59505	0.15
chr5_10693228_10693379	0.79	ANKRD33B-AS1	ANKRD33B antisense RNA 1	64966	0.1
chr5_142065201_142065574	0.79	FGF1	fibroblast growth factor 1 (acidic)	150	0.97
chr1_220474696_220474847	0.79	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	28975	0.2
chr6_113368126_113368394	0.79	ENSG00000201386	.	75565	0.13
chr1_54603167_54603369	0.78	CDCP2	CUB domain containing protein 2	16175	0.13
chr12_3260217_3260513	0.78	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	1402	0.51
chr3_183016185_183016744	0.78	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	33332	0.16
chr14_69155757_69156251	0.78	CTD-2325P2.3		3722	0.28
chr20_36793897_36794112	0.78	TGM2	transglutaminase 2	230	0.94
chr4_8474079_8474524	0.77	RP11-689P11.3		17632	0.17
chr3_175087290_175087441	0.77	ENSG00000264974	.	36	0.98
chr15_63034115_63034266	0.77	TLN2	talin 2	14901	0.19
chr8_122653910_122654608	0.77	HAS2-AS1	HAS2 antisense RNA 1	583	0.49
chr13_114882746_114882897	0.77	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	8526	0.22
chr8_62631448_62632036	0.77	ENSG00000264408	.	4395	0.26
chr17_36575458_36576074	0.77	ARHGAP23	Rho GTPase activating protein 23	8896	0.15
chr4_125350695_125350846	0.77	ANKRD50	ankyrin repeat domain 50	283117	0.01
chr6_140075834_140075985	0.76	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	380152	0.01
chr10_62760694_62761058	0.76	RHOBTB1	Rho-related BTB domain containing 1	322	0.94
chr10_79002477_79002676	0.76	RP11-328K22.1		71123	0.11
chr2_217664526_217664812	0.76	ENSG00000222832	.	6346	0.18
chr22_36422586_36422737	0.76	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	1812	0.48
chr1_68236550_68236701	0.76	ENSG00000238778	.	1711	0.42
chr1_219497938_219498089	0.76	RP11-135J2.4		150710	0.04
chr8_91483848_91484087	0.76	ENSG00000265157	.	8363	0.26
chr22_35998484_35998781	0.76	MB	myoglobin	13128	0.19
chr2_177410291_177410570	0.76	ENSG00000252027	.	118974	0.06
chr6_86128809_86128960	0.76	NT5E	5'-nucleotidase, ecto (CD73)	30925	0.23
chr3_194003235_194003464	0.75	CPN2	carboxypeptidase N, polypeptide 2	68698	0.1
chr1_178358349_178358628	0.75	RASAL2	RAS protein activator like 2	47882	0.16
chr11_3860839_3861570	0.75	RHOG	ras homolog family member G	868	0.42
chr6_139728038_139728189	0.75	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	32356	0.22
chr9_138916034_138916185	0.75	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	26317	0.18
chr12_52146069_52146338	0.75	AC068987.1	HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881	57586	0.12
chr2_232505608_232505920	0.75	ENSG00000239202	.	5220	0.2
chr14_105147050_105147307	0.75	ENSG00000265291	.	3092	0.18
chr12_53617356_53618344	0.75	RARG	retinoic acid receptor, gamma	3653	0.13
chr11_43597234_43597910	0.75	ENSG00000199077	.	5372	0.24
chr19_1168901_1169806	0.74	SBNO2	strawberry notch homolog 2 (Drosophila)	411	0.76
chr8_18993428_18993579	0.74	PSD3	pleckstrin and Sec7 domain containing 3	51263	0.17
chr17_47076838_47077332	0.74	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	1977	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:0071731	response to nitric oxide(GO:0071731)
0.4	1.1	GO:0061072	iris morphogenesis(GO:0061072)
0.4	1.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.3	1.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.3	1.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.3	0.9	GO:0071294	cellular response to zinc ion(GO:0071294)
0.3	0.8	GO:0030210	heparin biosynthetic process(GO:0030210)
0.3	0.3	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.3	1.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.9	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.2	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.6	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.2	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2	0.6	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.2	0.8	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.6	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2	0.8	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2	0.8	GO:0021670	lateral ventricle development(GO:0021670)
0.2	0.6	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2	1.9	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.2	0.4	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	0.7	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	1.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.7	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2	1.7	GO:0043277	apoptotic cell clearance(GO:0043277)
0.2	0.7	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.5	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.5	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.2	0.5	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	1.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.2	0.2	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	1.0	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.6	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.6	GO:0015705	iodide transport(GO:0015705)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.6	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.7	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.4	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.4	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.5	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.1	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.4	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.5	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.4	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.1	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.1	0.6	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.4	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.6	GO:0090102	cochlea development(GO:0090102)
0.1	0.5	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.4	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.1	0.4	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	1.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:0060433	bronchus development(GO:0060433)
0.1	1.0	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	0.3	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.1	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.1	0.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.1	GO:0072205	metanephric collecting duct development(GO:0072205)
0.1	0.4	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.1	GO:0060242	contact inhibition(GO:0060242)
0.1	0.7	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	0.3	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.3	GO:0001757	somite specification(GO:0001757)
0.1	0.4	GO:1902668	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1	0.2	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1	0.2	GO:0048853	forebrain morphogenesis(GO:0048853)
0.1	0.5	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.1	0.8	GO:0009629	response to gravity(GO:0009629)
0.1	0.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.6	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.1	0.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.4	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.3	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.3	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.1	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.9	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.3	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	1.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.3	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1	0.3	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.6	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.4	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	0.5	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.1	0.5	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.1	0.3	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.1	GO:0072044	collecting duct development(GO:0072044)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.1	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.1	0.4	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.8	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	1.2	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.3	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.6	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.1	0.3	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.2	GO:0060174	limb bud formation(GO:0060174)
0.1	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.2	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.2	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.5	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.1	0.2	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.1	0.7	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.2	GO:0051014	actin filament severing(GO:0051014)
0.1	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1	0.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.1	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	0.6	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.2	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.1	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.1	0.3	GO:0043276	anoikis(GO:0043276)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.9	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1	0.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.1	GO:0048820	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.1	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.6	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.1	0.2	GO:0051323	metaphase(GO:0051323)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.4	GO:0045217	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.2	GO:1904357	negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.6	GO:0060612	adipose tissue development(GO:0060612)
0.1	1.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.1	0.2	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.1	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.1	0.2	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	0.2	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1	0.4	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.1	GO:0001779	natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.1	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.3	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.1	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	0.2	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.3	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.1	0.2	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	0.3	GO:0009649	entrainment of circadian clock(GO:0009649)
0.1	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.2	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.5	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1	0.3	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.1	0.3	GO:0032964	collagen biosynthetic process(GO:0032964)
0.1	0.2	GO:0007144	female meiosis I(GO:0007144)
0.1	0.1	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.6	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0007143	female meiotic division(GO:0007143)
0.0	0.0	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.4	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.4	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0010896	regulation of triglyceride catabolic process(GO:0010896)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.3	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.3	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.7	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.7	GO:0007566	embryo implantation(GO:0007566)
0.0	0.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.2	GO:0010225	response to UV-C(GO:0010225)
0.0	0.6	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.3	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.9	GO:1903845	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0035850	epithelial cell differentiation involved in kidney development(GO:0035850)
0.0	0.2	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.2	GO:0007619	courtship behavior(GO:0007619)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.2	GO:0032106	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.3	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.2	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.5	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.4	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.3	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.3	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	1.5	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.3	GO:0033866	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.1	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.2	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.0	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0060405	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0	0.0	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.0	GO:0048486	parasympathetic nervous system development(GO:0048486)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.6	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	1.3	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.3	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.4	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.4	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.2	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.2	GO:0009437	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.3	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.3	GO:0021766	hippocampus development(GO:0021766)
0.0	0.0	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.0	GO:0044259	multicellular organismal macromolecule metabolic process(GO:0044259)
0.0	0.2	GO:1902591	vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0042762	regulation of sulfur metabolic process(GO:0042762)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0034651	cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0	0.0	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.6	GO:0016358	dendrite development(GO:0016358)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.2	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0051145	smooth muscle cell differentiation(GO:0051145)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:1901862	negative regulation of muscle organ development(GO:0048635) negative regulation of muscle tissue development(GO:1901862)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0051953	negative regulation of amine transport(GO:0051953) negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.2	GO:0060348	bone development(GO:0060348)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:1903513	endoplasmic reticulum to cytosol transport(GO:1903513)
0.0	0.1	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.5	GO:0007631	feeding behavior(GO:0007631)
0.0	0.1	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0030225	macrophage differentiation(GO:0030225)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.0	GO:0042537	benzene-containing compound metabolic process(GO:0042537)
0.0	0.1	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.0	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:1902224	ketone body metabolic process(GO:1902224)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.0	GO:0009310	amine catabolic process(GO:0009310) cellular biogenic amine catabolic process(GO:0042402)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.0	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0005588	collagen type V trimer(GO:0005588)
0.2	1.3	GO:0002102	podosome(GO:0002102)
0.2	0.9	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	1.2	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	1.0	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.7	GO:0005915	zonula adherens(GO:0005915)
0.1	0.4	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.5	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.7	GO:0001527	microfibril(GO:0001527)
0.1	0.4	GO:0032449	CBM complex(GO:0032449)
0.1	0.9	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.6	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.4	GO:0005638	lamin filament(GO:0005638)
0.1	0.1	GO:0032059	bleb(GO:0032059)
0.1	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.4	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	0.4	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.3	GO:0030904	retromer complex(GO:0030904)
0.1	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.6	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	1.0	GO:0005581	collagen trimer(GO:0005581)
0.1	0.5	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.3	GO:0043205	fibril(GO:0043205)
0.1	6.3	GO:0005925	focal adhesion(GO:0005925)
0.1	1.8	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	2.9	GO:0005604	basement membrane(GO:0005604)
0.1	0.2	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	9.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	1.2	GO:0030018	Z disc(GO:0030018)
0.0	2.4	GO:0030426	growth cone(GO:0030426)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.3	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	2.1	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	1.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0043656	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	2.3	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.7	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.5	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	2.7	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.3	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.7	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0000801	central element(GO:0000801)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.0	GO:0071778	obsolete WINAC complex(GO:0071778)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	1.6	GO:0005110	frizzled-2 binding(GO:0005110)
0.2	1.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.4	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.2	0.4	GO:0019215	intermediate filament binding(GO:0019215)
0.2	0.6	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.7	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.2	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	0.5	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.2	1.4	GO:0016595	glutamate binding(GO:0016595)
0.2	1.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	1.4	GO:0017166	vinculin binding(GO:0017166)
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.7	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.2	1.4	GO:0044548	S100 protein binding(GO:0044548)
0.2	0.5	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	0.6	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	1.7	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.2	1.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.4	GO:0005112	Notch binding(GO:0005112)
0.2	0.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.6	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.4	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.3	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.7	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	1.4	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	1.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.4	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.3	GO:0046848	hydroxyapatite binding(GO:0046848)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.1	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	1.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1	0.7	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.4	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.7	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.0	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.3	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.7	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.1	1.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1	0.3	GO:0046980	tapasin binding(GO:0046980)
0.1	0.5	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.5	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.3	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	1.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.6	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.3	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.7	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.8	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.6	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.5	GO:0070063	RNA polymerase binding(GO:0070063)
0.1	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	2.9	GO:0005518	collagen binding(GO:0005518)
0.1	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.2	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.5	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.5	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.4	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.5	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.6	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.3	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.6	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.3	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
0.1	2.2	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	0.2	GO:0043495	protein anchor(GO:0043495)
0.1	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	1.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	2.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.8	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.3	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.4	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.4	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.4	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.4	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.3	GO:0016248	channel inhibitor activity(GO:0016248)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.0	GO:0030547	receptor inhibitor activity(GO:0030547)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0008483	transaminase activity(GO:0008483)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	0.5	PID REELIN PATHWAY	Reelin signaling pathway
0.2	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	0.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	2.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	4.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.7	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	2.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	10.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	0.7	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.1	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	1.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.2	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	4.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.8	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.0	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	1.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	1.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.9	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	2.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors

Results for EPAS1_BCL3

Z-value: 3.77

Motif logo

Transcription factors associated with EPAS1_BCL3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the EPAS1_BCL3 motif across conditions

Conditions sorted by the z-value of the EPAS1_BCL3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: