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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ESR1

Z-value: 1.93

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Transcription factors associated with ESR1

Gene Symbol	Gene ID	Gene Info
ESR1 Ensembl NCBI GeneCards UniProt	ENSG00000091831.17	estrogen receptor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_152011385_152011536	ESR1	171	0.968833	-0.80	1.0e-02	Click!
chr6_152012412_152012563	ESR1	856	0.711449	0.79	1.1e-02	Click!
chr6_152023478_152023738	ESR1	11977	0.261429	-0.78	1.3e-02	Click!
chr6_152129326_152129477	ESR1	587	0.795068	0.78	1.4e-02	Click!
chr6_152290545_152290696	ESR1	88828	0.094008	0.78	1.4e-02	Click!

Activity of the ESR1 motif across conditions

Conditions sorted by the z-value of the ESR1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_20134359_20134761	0.80	NAV2-AS1	NAV2 antisense RNA 1	7618	0.23
chr3_159572255_159572681	0.75	SCHIP1	schwannomin interacting protein 1	1740	0.37
chr7_29605198_29605734	0.67	PRR15	proline rich 15	400	0.84
chr17_40670908_40671198	0.66	ENSG00000265611	.	4847	0.09
chr1_36808619_36809165	0.66	STK40	serine/threonine kinase 40	18049	0.12
chr10_73605525_73605859	0.60	ENSG00000238446	.	1141	0.49
chr10_81029619_81029967	0.58	ZMIZ1	zinc finger, MIZ-type containing 1	36182	0.19
chr5_1515989_1516747	0.58	LPCAT1	lysophosphatidylcholine acyltransferase 1	7724	0.23
chr8_10590583_10590855	0.55	SOX7	SRY (sex determining region Y)-box 7	2697	0.21
chr10_115438620_115438948	0.55	CASP7	caspase 7, apoptosis-related cysteine peptidase	158	0.96
chr14_69407567_69407834	0.55	ACTN1	actinin, alpha 1	6565	0.25
chr14_105860468_105860995	0.55	PACS2	phosphofurin acidic cluster sorting protein 2	2935	0.17
chr20_30147783_30148009	0.52	HM13-IT1	HM13 intronic transcript 1 (non-protein coding)	3073	0.16
chr14_59827605_59828209	0.51	ENSG00000252869	.	38834	0.18
chr16_31142356_31142648	0.50	RP11-388M20.2		252	0.77
chr18_43209000_43209203	0.49	SLC14A2	solute carrier family 14 (urea transporter), member 2	14335	0.2
chr3_183265897_183266131	0.45	KLHL6-AS1	KLHL6 antisense RNA 1	509	0.77
chr17_62151470_62151864	0.45	ICAM2	intercellular adhesion molecule 2	53673	0.09
chr7_92393722_92393991	0.44	ENSG00000206763	.	62728	0.11
chr13_75990856_75991087	0.43	TBC1D4-AS1	TBC1D4 antisense RNA 1	39541	0.17
chr3_52105187_52105355	0.43	LINC00696	long intergenic non-protein coding RNA 696	7704	0.13
chr1_22258402_22258722	0.43	HSPG2	heparan sulfate proteoglycan 2	5228	0.16
chr1_9498721_9499110	0.41	ENSG00000252956	.	1078	0.6
chr4_8192745_8193409	0.41	SH3TC1	SH3 domain and tetratricopeptide repeats 1	8014	0.22
chr17_55976704_55976873	0.41	CUEDC1	CUE domain containing 1	3962	0.21
chr1_6532022_6532173	0.41	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	5842	0.12
chr1_153598933_153599084	0.41	S100A13	S100 calcium binding protein A13	516	0.52
chr9_137270522_137271255	0.41	ENSG00000263897	.	369	0.9
chr14_69412745_69412910	0.40	ACTN1	actinin, alpha 1	1438	0.48
chr3_50355712_50356133	0.40	HYAL2	hyaluronoglucosaminidase 2	2457	0.1
chr16_11295208_11295453	0.40	RMI2	RecQ mediated genome instability 2	48176	0.08
chr22_43318424_43318765	0.40	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	23285	0.2
chr6_20877296_20877733	0.40	RP3-348I23.2		76589	0.12
chr14_89894960_89895143	0.40	FOXN3-AS1	FOXN3 antisense RNA 1	11353	0.17
chr1_55518675_55518972	0.40	PCSK9	proprotein convertase subtilisin/kexin type 9	12928	0.2
chr2_9392225_9392385	0.39	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	45411	0.18
chr17_79971752_79971903	0.39	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	3140	0.09
chr17_36740635_36740786	0.39	CTB-58E17.2		16592	0.13
chr14_103578139_103578290	0.39	EXOC3L4	exocyst complex component 3-like 4	4361	0.19
chr11_46360145_46360296	0.39	DGKZ	diacylglycerol kinase, zeta	72	0.97
chr20_61463306_61463766	0.38	COL9A3	collagen, type IX, alpha 3	14373	0.11
chr11_63640497_63640654	0.38	MARK2	MAP/microtubule affinity-regulating kinase 2	3827	0.17
chr10_30101231_30101626	0.38	SVIL	supervillin	76695	0.11
chr9_136996353_136996504	0.38	WDR5	WD repeat domain 5	4059	0.19
chr8_123928226_123928643	0.37	ZHX2	zinc fingers and homeoboxes 2	52810	0.12
chr1_27868563_27868910	0.37	RP1-159A19.4		16420	0.16
chr8_129180533_129180792	0.37	ENSG00000221261	.	18300	0.23
chr16_66544956_66545128	0.37	TK2	thymidine kinase 2, mitochondrial	2644	0.17
chr22_30194899_30195349	0.37	ASCC2	activating signal cointegrator 1 complex subunit 2	2967	0.2
chr1_21588447_21588832	0.37	RP3-329E20.2		3936	0.22
chr2_8640925_8641201	0.37	AC011747.7		174833	0.03
chr2_9427415_9427711	0.36	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	80669	0.1
chr2_131111615_131111766	0.36	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	1890	0.27
chr12_109115682_109115890	0.36	CORO1C	coronin, actin binding protein, 1C	8541	0.16
chr15_40627004_40627253	0.36	C15orf52	chromosome 15 open reading frame 52	3113	0.1
chr3_11243097_11243459	0.36	HRH1	histamine receptor H1	24439	0.24
chr20_34685745_34686271	0.36	EPB41L1	erythrocyte membrane protein band 4.1-like 1	5249	0.2
chr17_47533894_47534339	0.36	NGFR	nerve growth factor receptor	38539	0.1
chr14_65293424_65293575	0.36	SPTB	spectrin, beta, erythrocytic	3633	0.24
chr10_126029460_126029611	0.36	OAT	ornithine aminotransferase	77970	0.1
chr1_22258230_22258381	0.36	HSPG2	heparan sulfate proteoglycan 2	5485	0.16
chr9_137261966_137262247	0.36	ENSG00000263897	.	9151	0.25
chr11_12088585_12089097	0.36	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	26702	0.22
chr8_142289717_142289880	0.35	RP11-10J21.3	Uncharacterized protein	25134	0.12
chr19_41731212_41731363	0.35	AXL	AXL receptor tyrosine kinase	1373	0.29
chr1_184761453_184761811	0.35	FAM129A	family with sequence similarity 129, member A	13487	0.2
chr9_139257302_139257550	0.35	DNLZ	DNL-type zinc finger	745	0.51
chr17_55954346_55954647	0.35	CUEDC1	CUE domain containing 1	4465	0.2
chr3_50176368_50176664	0.35	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	15962	0.12
chr3_72235398_72235672	0.34	ENSG00000212070	.	76044	0.12
chr17_79378177_79378500	0.34	ENSG00000266392	.	3760	0.14
chr7_151385205_151385463	0.34	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	48015	0.15
chr1_42627613_42628057	0.34	GUCA2A	guanylate cyclase activator 2A (guanylin)	2554	0.29
chr14_69405435_69405631	0.34	ACTN1	actinin, alpha 1	8732	0.24
chr4_139327703_139328022	0.34	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	164359	0.04
chr11_62380549_62380700	0.34	ROM1	retinal outer segment membrane protein 1	377	0.4
chr21_38232225_38232376	0.34	ENSG00000199806	.	8089	0.23
chr6_8083142_8083550	0.34	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	14198	0.22
chr6_15222233_15222384	0.34	JARID2	jumonji, AT rich interactive domain 2	24219	0.18
chr11_64878272_64878458	0.34	VPS51	vacuolar protein sorting 51 homolog (S. cerevisiae)	411	0.47
chr8_96238091_96238242	0.34	C8orf37	chromosome 8 open reading frame 37	43263	0.17
chr20_1317307_1317796	0.33	AL136531.1	HCG2043693; Uncharacterized protein	4	0.97
chr9_130906009_130906346	0.33	LCN2	lipocalin 2	5173	0.09
chr11_111609200_111609351	0.33	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	16487	0.17
chr22_30648620_30649241	0.33	LIF	leukemia inhibitory factor	6090	0.11
chr2_169426823_169427210	0.33	ENSG00000265694	.	12437	0.23
chr19_2636442_2636925	0.33	CTC-265F19.3		4731	0.15
chr1_47691411_47691617	0.33	RP1-18D14.7		45	0.97
chr9_94533727_94534271	0.33	ENSG00000266855	.	135466	0.05
chr2_43152306_43152732	0.33	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	132787	0.05
chr22_45625921_45626224	0.33	KIAA0930	KIAA0930	3288	0.23
chr4_151097529_151097680	0.33	ENSG00000238721	.	33254	0.22
chr11_10609186_10609457	0.33	MRVI1-AS1	MRVI1 antisense RNA 1	5423	0.19
chr22_44759775_44760116	0.33	RP1-32I10.10	Uncharacterized protein	1486	0.51
chr17_1655742_1656238	0.33	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	9263	0.1
chr1_3633020_3633399	0.33	RP5-1092A11.2		2347	0.18
chr6_133085395_133085546	0.32	VNN2	vanin 2	872	0.48
chr18_46510269_46510564	0.32	SMAD7	SMAD family member 7	33335	0.16
chr1_151579139_151579290	0.32	SNX27	sorting nexin family member 27	5344	0.12
chr10_80850413_80850863	0.32	ZMIZ1	zinc finger, MIZ-type containing 1	21846	0.22
chr17_55967739_55968110	0.32	CUEDC1	CUE domain containing 1	2125	0.29
chr19_5260963_5261211	0.32	PTPRS	protein tyrosine phosphatase, receptor type, S	25087	0.21
chr9_96919191_96919602	0.32	ENSG00000199165	.	18838	0.15
chr9_124032094_124032357	0.32	GSN	gelsolin	1845	0.28
chr20_1842593_1842744	0.32	SIRPA	signal-regulatory protein alpha	32486	0.19
chr21_44614410_44614785	0.32	CRYAA	crystallin, alpha A	24331	0.16
chr2_65608934_65609351	0.32	AC012370.2		1323	0.48
chr22_37908037_37908429	0.32	CARD10	caspase recruitment domain family, member 10	15	0.97
chr11_19941032_19941183	0.32	NAV2-AS3	NAV2 antisense RNA 3	61776	0.13
chr1_28455497_28456106	0.31	ENSG00000253005	.	13551	0.13
chr17_55981324_55981475	0.31	CUEDC1	CUE domain containing 1	649	0.69
chr16_70740874_70741025	0.31	VAC14	Vac14 homolog (S. cerevisiae)	6801	0.15
chr7_129912749_129913103	0.31	CPA2	carboxypeptidase A2 (pancreatic)	6259	0.15
chr14_69409711_69409862	0.31	ACTN1	actinin, alpha 1	4479	0.27
chr16_638089_638338	0.31	RAB40C	RAB40C, member RAS oncogene family	1144	0.24
chr9_14273530_14273681	0.31	NFIB	nuclear factor I/B	34407	0.21
chr19_11252797_11253239	0.31	SPC24	SPC24, NDC80 kinetochore complex component	13419	0.13
chr2_241327570_241327721	0.31	GPC1	glypican 1	47443	0.12
chr3_119854481_119854726	0.31	ENSG00000244139	.	13847	0.18
chr8_56861171_56861322	0.31	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	8453	0.16
chrX_152084026_152084274	0.31	ZNF185	zinc finger protein 185 (LIM domain)	1116	0.5
chr1_16083104_16083325	0.31	FBLIM1	filamin binding LIM protein 1	60	0.95
chr6_7165580_7166040	0.31	RP11-405O10.2		17506	0.17
chr8_61862675_61863209	0.31	CLVS1	clavesin 1	106775	0.07
chr11_67805590_67806035	0.31	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	671	0.53
chr22_25460867_25461018	0.31	KIAA1671	KIAA1671	4994	0.26
chr6_138291326_138291739	0.31	RP11-356I2.4		102162	0.07
chr7_139426374_139426898	0.30	HIPK2	homeodomain interacting protein kinase 2	4795	0.29
chr13_31438557_31438708	0.30	MEDAG	mesenteric estrogen-dependent adipogenesis	41696	0.16
chr22_19161927_19162579	0.30	AC004463.6		3345	0.15
chr17_42423914_42424082	0.30	GRN	granulin	1325	0.25
chr15_62737179_62737605	0.30	TLN2	talin 2	116172	0.06
chr9_125156330_125156481	0.30	AL162424.1	Uncharacterized protein	7477	0.13
chr2_121943870_121944021	0.30	TFCP2L1	transcription factor CP2-like 1	98838	0.08
chr7_55253756_55253907	0.30	EGFR-AS1	EGFR antisense RNA 1	2796	0.38
chr8_42409885_42410036	0.30	SMIM19	small integral membrane protein 19	8389	0.18
chr1_28517417_28517723	0.30	PTAFR	platelet-activating factor receptor	2814	0.15
chr13_52412121_52412530	0.30	CCDC70	coiled-coil domain containing 70	23792	0.17
chr3_132757241_132757419	0.30	TMEM108	transmembrane protein 108	69	0.99
chr11_65257627_65258285	0.30	SCYL1	SCY1-like 1 (S. cerevisiae)	34592	0.08
chr1_203172034_203172338	0.30	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	16309	0.13
chr9_91390340_91390723	0.30	ENSG00000265873	.	29711	0.24
chr22_20191302_20191696	0.30	XXbac-B444P24.8		942	0.46
chr3_45589006_45589723	0.30	LARS2-AS1	LARS2 antisense RNA 1	38327	0.14
chr17_72782415_72782574	0.30	TMEM104	transmembrane protein 104	9835	0.11
chr16_2211619_2211770	0.29	TRAF7	TNF receptor-associated factor 7, E3 ubiquitin protein ligase	1849	0.12
chr14_93403837_93403988	0.29	CHGA	chromogranin A (parathyroid secretory protein 1)	14391	0.25
chr11_33963443_33963781	0.29	LMO2	LIM domain only 2 (rhombotin-like 1)	49776	0.14
chr8_48343958_48344189	0.29	SPIDR	scaffolding protein involved in DNA repair	8890	0.29
chr15_33360065_33360419	0.29	FMN1	formin 1	121	0.98
chr3_63710485_63710636	0.29	SNTN	sentan, cilia apical structure protein	72186	0.09
chr17_76704134_76704285	0.29	CYTH1	cytohesin 1	8898	0.2
chr16_12282215_12282366	0.29	SNX29	sorting nexin 29	58736	0.11
chr1_160095186_160095337	0.29	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	2201	0.19
chr17_74542392_74542689	0.29	RP11-666A8.7		3493	0.09
chr1_3620112_3620445	0.29	TP73	tumor protein p73	5656	0.13
chr1_21620651_21620932	0.29	ECE1	endothelin converting enzyme 1	126	0.93
chr18_9704973_9705544	0.29	RAB31	RAB31, member RAS oncogene family	2904	0.31
chr2_218793437_218793804	0.29	TNS1	tensin 1	8265	0.24
chr18_46517444_46517630	0.29	RP11-15F12.1		32536	0.16
chr2_43466747_43467191	0.29	AC010883.5		10257	0.23
chr6_17933009_17933323	0.29	KIF13A	kinesin family member 13A	54528	0.15
chr17_8762469_8762816	0.29	PIK3R6	phosphoinositide-3-kinase, regulatory subunit 6	8352	0.2
chr17_17740781_17741345	0.29	SREBF1	sterol regulatory element binding transcription factor 1	738	0.58
chr1_183250951_183251102	0.28	NMNAT2	nicotinamide nucleotide adenylyltransferase 2	22983	0.23
chr2_206809249_206809511	0.28	ENSG00000201875	.	44026	0.13
chr7_906996_907156	0.28	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	9113	0.15
chr18_43749824_43749975	0.28	C18orf25	chromosome 18 open reading frame 25	3620	0.25
chr3_112931713_112931990	0.28	BOC	BOC cell adhesion associated, oncogene regulated	442	0.86
chr14_35806722_35806916	0.28	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	26780	0.19
chr11_95086535_95086686	0.28	ENSG00000201204	.	119928	0.06
chr11_72896529_72896905	0.28	RP11-800A3.2		30241	0.13
chr20_52235971_52236462	0.28	ZNF217	zinc finger protein 217	10785	0.21
chr6_167037122_167037303	0.28	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	3513	0.32
chr3_31857579_31857730	0.28	OSBPL10	oxysterol binding protein-like 10	13912	0.27
chr5_14204722_14204930	0.28	TRIO	trio Rho guanine nucleotide exchange factor	20919	0.29
chr5_176920924_176921139	0.28	RP11-1334A24.6		965	0.35
chr4_41144342_41144612	0.28	ENSG00000207198	.	28518	0.18
chr16_70425965_70426116	0.28	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	8501	0.12
chr4_128544405_128544987	0.28	INTU	inturned planar cell polarity protein	270	0.95
chr6_90529041_90529192	0.28	MDN1	MDN1, midasin homolog (yeast)	321	0.87
chr4_3487177_3487367	0.28	RP11-529E10.6		18912	0.14
chr9_19999717_20000054	0.28	ENSG00000266224	.	170134	0.03
chr1_61803481_61803729	0.28	NFIA	nuclear factor I/A	14517	0.3
chr3_197036693_197037063	0.28	DLG1	discs, large homolog 1 (Drosophila)	10707	0.16
chr21_43352747_43353275	0.28	C2CD2	C2 calcium-dependent domain containing 2	6212	0.19
chr4_5638816_5638967	0.28	EVC2	Ellis van Creveld syndrome 2	71403	0.11
chr10_101946913_101947666	0.28	ERLIN1	ER lipid raft associated 1	802	0.51
chr6_82649464_82649641	0.28	ENSG00000206886	.	175811	0.03
chr1_203482695_203483217	0.28	OPTC	opticin	17858	0.21
chr11_33963006_33963250	0.28	LMO2	LIM domain only 2 (rhombotin-like 1)	49292	0.14
chr1_203194147_203194370	0.28	CHIT1	chitinase 1 (chitotriosidase)	4541	0.19
chr16_9141084_9141235	0.28	C16orf72	chromosome 16 open reading frame 72	44346	0.12
chr17_76137750_76137971	0.28	C17orf99	chromosome 17 open reading frame 99	4574	0.12
chr16_85558860_85559293	0.28	ENSG00000264203	.	83978	0.08
chr12_52400893_52401105	0.27	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	275	0.87
chr5_140908442_140908593	0.27	DIAPH1	diaphanous-related formin 1	2803	0.16
chr8_65488684_65489072	0.27	RP11-21C4.1		942	0.63
chr17_80607445_80607596	0.27	WDR45B	WD repeat domain 45B	1109	0.35
chr9_98275007_98275158	0.27	RP11-435O5.4		1245	0.41

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.2	0.5	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.2	0.6	GO:0018101	protein citrullination(GO:0018101)
0.1	0.4	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0060433	bronchus development(GO:0060433)
0.1	0.4	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	1.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.2	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.4	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.4	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.1	0.3	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.1	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.5	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.3	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.5	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.1	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.2	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.8	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.1	0.2	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0048570	notochord morphogenesis(GO:0048570)
0.1	0.6	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.2	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.4	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.1	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.3	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	0.2	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.2	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.3	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.2	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.1	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.5	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.2	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1	0.2	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.1	0.3	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.2	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	0.4	GO:0015884	folic acid transport(GO:0015884)
0.1	0.2	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.2	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	0.2	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.1	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1	0.2	GO:0043276	anoikis(GO:0043276)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.2	GO:0042448	progesterone metabolic process(GO:0042448)
0.1	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.2	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.3	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.3	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0032329	serine transport(GO:0032329)
0.0	0.3	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.4	GO:0009629	response to gravity(GO:0009629)
0.0	0.3	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.3	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.0	GO:2000380	regulation of mesodermal cell fate specification(GO:0042661) lateral mesoderm development(GO:0048368) regulation of mesoderm development(GO:2000380)
0.0	0.2	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.2	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.7	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.3	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.2	GO:0030825	positive regulation of cGMP metabolic process(GO:0030825)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0010224	response to UV-B(GO:0010224)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.3	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.2	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.2	GO:0051900	regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.0	0.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0045924	regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.0	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.3	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.3	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.0	GO:0060055	angiogenesis involved in wound healing(GO:0060055) vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.2	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.2	GO:0090398	cellular senescence(GO:0090398)
0.0	0.4	GO:1901224	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.2	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.6	GO:0007044	cell-substrate junction assembly(GO:0007044)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.2	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0007418	ventral midline development(GO:0007418)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.1	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0034442	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.3	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0042116	macrophage activation(GO:0042116)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.0	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0010889	regulation of sequestering of triglyceride(GO:0010889)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0061082	myeloid leukocyte cytokine production(GO:0061082)
0.0	0.0	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.2	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.0	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	1.1	GO:0006826	iron ion transport(GO:0006826)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.3	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.2	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.1	GO:0019755	one-carbon compound transport(GO:0019755)
0.0	0.2	GO:0010165	response to X-ray(GO:0010165)
0.0	0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0048713	regulation of oligodendrocyte differentiation(GO:0048713)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.1	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0051918	regulation of fibrinolysis(GO:0051917) negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0061035	regulation of cartilage development(GO:0061035)
0.0	0.2	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.2	GO:0051058	negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0018200	peptidyl-glutamic acid modification(GO:0018200)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.2	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.1	GO:0051570	negative regulation of histone methylation(GO:0031061) regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0042304	regulation of fatty acid biosynthetic process(GO:0042304)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:0009081	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	1.1	GO:0034329	cell junction assembly(GO:0034329)
0.0	0.0	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.1	GO:0010226	response to lithium ion(GO:0010226)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0046134	pyrimidine nucleoside biosynthetic process(GO:0046134)
0.0	0.0	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0019048	modulation by virus of host morphology or physiology(GO:0019048)
0.0	0.2	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.1	GO:0006027	aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0021988	olfactory lobe development(GO:0021988)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.4	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0090312	positive regulation of histone deacetylation(GO:0031065) positive regulation of protein deacetylation(GO:0090312)
0.0	0.2	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.0	GO:0045006	DNA deamination(GO:0045006)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0031143	pseudopodium(GO:0031143)
0.1	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.7	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.6	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	3.3	GO:0005925	focal adhesion(GO:0005925)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.7	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.5	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0005912	adherens junction(GO:0005912)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0042641	actomyosin(GO:0042641)
0.0	0.0	GO:0042825	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0031045	dense core granule(GO:0031045)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0043204	perikaryon(GO:0043204)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.3	GO:0030018	Z disc(GO:0030018)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.6	GO:0030017	sarcomere(GO:0030017)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.4	GO:0097223	acrosomal vesicle(GO:0001669) sperm part(GO:0097223)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	2.2	GO:0005792	obsolete microsome(GO:0005792)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	0.6	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	1.1	GO:0017166	vinculin binding(GO:0017166)
0.1	0.3	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.3	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.3	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.4	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0008061	chitin binding(GO:0008061)
0.1	0.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.4	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.3	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.4	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.3	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.2	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.4	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1	0.5	GO:0005112	Notch binding(GO:0005112)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	0.3	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.2	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.3	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.5	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.1	0.3	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.3	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.4	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.4	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0002060	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	1.3	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.4	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.3	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.7	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.4	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0032142	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.4	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.0	GO:0019203	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0008253	nucleotidase activity(GO:0008252) 5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.2	GO:0016248	channel inhibitor activity(GO:0016248)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0046980	tapasin binding(GO:0046980)
0.0	0.5	GO:0002020	protease binding(GO:0002020)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0005372	water transmembrane transporter activity(GO:0005372)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.2	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.3	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.0	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism

Results for ESR1

Z-value: 1.93

Motif logo

Transcription factors associated with ESR1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ESR1 motif across conditions

Conditions sorted by the z-value of the ESR1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: