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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ESRRB_ESRRG

Z-value: 1.61

Motif logo

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ENSG00000119715.10 ESRRB
ENSG00000196482.12 ESRRG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ESRRBchr14_76981672_769818241078670.0659130.551.3e-01Click!
ESRRBchr14_76918551_76918702447450.1708000.491.8e-01Click!
ESRRBchr14_76881096_7688124772900.2554140.402.8e-01Click!
ESRRBchr14_77001333_770014841275270.0507700.393.0e-01Click!
ESRRBchr14_76997804_769979551239980.0531350.383.1e-01Click!
ESRRGchr1_217448110_2174482611370880.052919-0.901.0e-03Click!
ESRRGchr1_217449127_2174492781381050.052251-0.881.8e-03Click!
ESRRGchr1_217448334_2174484851373120.052771-0.872.1e-03Click!
ESRRGchr1_217449425_2174495761384030.052058-0.835.9e-03Click!
ESRRGchr1_217216787_217216938333690.2539940.665.1e-02Click!

Activity of the ESRRB_ESRRG motif across conditions

Conditions sorted by the z-value of the ESRRB_ESRRG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_56039749_56039992 3.83 CTCFL
CCCTC-binding factor (zinc finger protein)-like
59443
0.1
chr11_67173408_67173659 2.08 TBC1D10C
TBC1 domain family, member 10C
1873
0.13
chr11_72864714_72865145 1.10 FCHSD2
FCH and double SH3 domains 2
11623
0.2
chr3_16326802_16326964 1.02 OXNAD1
oxidoreductase NAD-binding domain containing 1
16135
0.16
chr6_41170433_41170835 0.93 TREML2
triggering receptor expressed on myeloid cells-like 2
1702
0.26
chr8_131025939_131026245 0.89 FAM49B
family with sequence similarity 49, member B
2559
0.24
chr4_6920362_6920560 0.88 TBC1D14
TBC1 domain family, member 14
8486
0.18
chr17_2726619_2727134 0.85 RAP1GAP2
RAP1 GTPase activating protein 2
27100
0.16
chr6_33775484_33775750 0.85 MLN
motilin
3829
0.22
chr2_113937603_113937798 0.85 AC016683.5

4763
0.16
chr12_7063873_7064421 0.84 PTPN6
protein tyrosine phosphatase, non-receptor type 6
3609
0.07
chr10_126416114_126416281 0.83 FAM53B
family with sequence similarity 53, member B
15342
0.16
chr7_76869055_76869341 0.82 AC073635.5

18242
0.2
chr12_15134400_15134556 0.81 PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
8522
0.18
chr9_130545994_130546281 0.80 CDK9
cyclin-dependent kinase 9
1821
0.16
chr1_26865150_26865301 0.80 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
4378
0.16
chr3_14418676_14418859 0.80 ENSG00000199609
.
17381
0.21
chr6_24939842_24940244 0.79 FAM65B
family with sequence similarity 65, member B
3855
0.28
chr7_151048881_151049036 0.78 NUB1
negative regulator of ubiquitin-like proteins 1
6527
0.16
chr20_20714651_20715009 0.77 ENSG00000264361
.
4544
0.29
chr1_114483922_114484073 0.77 HIPK1
homeodomain interacting protein kinase 1
9770
0.13
chr18_60806585_60806736 0.77 RP11-299P2.1

11893
0.25
chr12_31986291_31986442 0.77 ENSG00000252204
.
22344
0.16
chr18_2967144_2967376 0.75 RP11-737O24.1

244
0.91
chr6_24962302_24962654 0.74 FAM65B
family with sequence similarity 65, member B
26290
0.19
chr9_95792448_95792761 0.73 FGD3
FYVE, RhoGEF and PH domain containing 3
15262
0.18
chr5_57840573_57840724 0.72 CTD-2117L12.1
Uncharacterized protein
13422
0.18
chr12_50064566_50064804 0.72 FMNL3
formin-like 3
36318
0.11
chr4_68441371_68441728 0.71 STAP1
signal transducing adaptor family member 1
17103
0.2
chr17_3864337_3864743 0.71 ATP2A3
ATPase, Ca++ transporting, ubiquitous
3045
0.24
chr19_13993263_13993689 0.71 NANOS3
nanos homolog 3 (Drosophila)
5413
0.09
chr8_21436069_21436236 0.70 ENSG00000266630
.
28643
0.23
chr18_60880832_60881273 0.70 ENSG00000238988
.
19154
0.21
chr1_28318555_28318747 0.69 RP11-460I13.2

31947
0.1
chr2_102239339_102239566 0.69 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
73860
0.12
chr15_78395422_78395756 0.69 SH2D7
SH2 domain containing 7
10662
0.13
chr11_67173722_67173982 0.67 TBC1D10C
TBC1 domain family, member 10C
2192
0.12
chr1_26642939_26643090 0.67 CD52
CD52 molecule
1434
0.25
chr1_228999751_228999959 0.67 RHOU
ras homolog family member U
129031
0.04
chr17_43297507_43297734 0.67 CTD-2020K17.1

79
0.93
chr5_142156918_142157069 0.66 ARHGAP26
Rho GTPase activating protein 26
4711
0.3
chr21_47979710_47980000 0.66 ENSG00000272283
.
24146
0.15
chr1_112018428_112019095 0.66 C1orf162
chromosome 1 open reading frame 162
2270
0.16
chr20_35583518_35583882 0.65 SAMHD1
SAM domain and HD domain 1
3454
0.28
chr16_27210586_27210926 0.65 KDM8
lysine (K)-specific demethylase 8
4051
0.22
chr10_11203289_11203522 0.65 CELF2
CUGBP, Elav-like family member 2
3588
0.26
chr5_150517774_150517925 0.65 ANXA6
annexin A6
3352
0.26
chr17_76757237_76757578 0.64 CYTH1
cytohesin 1
20947
0.17
chr1_206942061_206942212 0.64 IL10
interleukin 10
3703
0.19
chr12_45363108_45363259 0.64 NELL2
NEL-like 2 (chicken)
47552
0.15
chr4_15758963_15759136 0.64 CD38
CD38 molecule
20852
0.19
chr11_118087590_118088000 0.64 AMICA1
adhesion molecule, interacts with CXADR antigen 1
2189
0.24
chr2_234318940_234319134 0.64 DGKD
diacylglycerol kinase, delta 130kDa
22237
0.15
chr8_27263857_27264174 0.63 PTK2B
protein tyrosine kinase 2 beta
9046
0.23
chr1_206942223_206942745 0.62 IL10
interleukin 10
3355
0.2
chr6_14373007_14373158 0.62 ENSG00000238987
.
216389
0.02
chr20_20725126_20725277 0.61 ENSG00000264361
.
5827
0.28
chr8_27262728_27262897 0.61 PTK2B
protein tyrosine kinase 2 beta
7843
0.23
chr19_1073176_1073340 0.60 HMHA1
histocompatibility (minor) HA-1
1746
0.19
chr9_36139739_36139903 0.60 GLIPR2
GLI pathogenesis-related 2
3079
0.25
chr14_52331770_52332050 0.59 GNG2
guanine nucleotide binding protein (G protein), gamma 2
3868
0.25
chr2_68432811_68432962 0.59 ENSG00000216115
.
24172
0.12
chr19_42705324_42705478 0.59 ENSG00000265122
.
8171
0.09
chr20_47352393_47352549 0.59 ENSG00000251876
.
3514
0.35
chr11_128599507_128599754 0.58 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
33712
0.15
chr1_145452429_145452580 0.58 TXNIP
thioredoxin interacting protein
13198
0.1
chr20_1344489_1344952 0.57 RP11-314N13.3

2454
0.22
chr1_42255513_42255703 0.57 ENSG00000264896
.
30796
0.23
chr14_107080930_107081145 0.57 IGHV1-58
immunoglobulin heavy variable 1-58
2168
0.06
chr8_71275992_71276158 0.57 ENSG00000207036
.
6493
0.25
chr1_200984271_200984521 0.57 KIF21B
kinesin family member 21B
8140
0.19
chr5_75705956_75706117 0.57 IQGAP2
IQ motif containing GTPase activating protein 2
5787
0.3
chr22_17701465_17701764 0.57 CECR1
cat eye syndrome chromosome region, candidate 1
1124
0.53
chr5_133560624_133561078 0.57 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
394
0.54
chr1_12231932_12232095 0.57 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
4953
0.18
chr6_90088731_90088882 0.57 UBE2J1
ubiquitin-conjugating enzyme E2, J1
26239
0.16
chr7_130715778_130716117 0.56 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
21362
0.2
chr12_111842321_111842586 0.56 SH2B3
SH2B adaptor protein 3
1299
0.45
chr12_55382686_55382958 0.56 TESPA1
thymocyte expressed, positive selection associated 1
4292
0.26
chr2_25558574_25558742 0.56 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
6096
0.22
chr10_17469337_17469935 0.56 ST8SIA6-AS1
ST8SIA6 antisense RNA 1
19610
0.17
chr16_69459124_69459339 0.56 CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
545
0.72
chr6_35010733_35010884 0.56 TCP11
t-complex 11, testis-specific
78014
0.09
chr22_39843923_39844104 0.55 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
9336
0.15
chr2_32490514_32490792 0.55 NLRC4
NLR family, CARD domain containing 4
148
0.96
chr3_187698200_187698351 0.55 LPP
LIM domain containing preferred translocation partner in lipoma
172797
0.03
chr8_8646250_8646447 0.55 CLDN23
claudin 23
86900
0.08
chr4_40156378_40156529 0.55 RP11-395I6.3

11842
0.19
chr13_41188423_41188902 0.55 FOXO1
forkhead box O1
52072
0.14
chr16_81502646_81502945 0.55 CMIP
c-Maf inducing protein
24020
0.23
chr13_78299657_78299947 0.55 SLAIN1
SLAIN motif family, member 1
6069
0.24
chr15_45008559_45008779 0.54 B2M
beta-2-microglobulin
4954
0.16
chr14_91855068_91855898 0.54 CCDC88C
coiled-coil domain containing 88C
28207
0.19
chr2_190424501_190424725 0.54 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
21000
0.22
chr19_54880893_54881262 0.54 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
981
0.39
chr2_43402387_43402951 0.54 ZFP36L2
ZFP36 ring finger protein-like 2
51079
0.14
chr21_34568332_34568483 0.54 C21orf54
chromosome 21 open reading frame 54
25866
0.13
chr11_12155195_12155639 0.54 MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
4518
0.31
chr13_28006578_28006898 0.54 GTF3A
general transcription factor IIIA
2643
0.24
chr4_100776363_100776514 0.54 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
38435
0.15
chr2_131127308_131127459 0.54 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
279
0.89
chr18_9185859_9186010 0.54 ANKRD12
ankyrin repeat domain 12
3550
0.22
chr16_75094649_75094937 0.53 ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
43889
0.12
chr8_100875595_100875746 0.53 COX6C
cytochrome c oxidase subunit VIc
29693
0.19
chr12_94518026_94518226 0.53 PLXNC1
plexin C1
24373
0.2
chr16_30176524_30176675 0.53 CORO1A
coronin, actin binding protein, 1A
17549
0.07
chr2_7061705_7061856 0.53 ENSG00000228203
.
2940
0.24
chr17_81074523_81074674 0.53 METRNL
meteorin, glial cell differentiation regulator-like
22604
0.23
chr1_31196900_31197104 0.53 MATN1
matrilin 1, cartilage matrix protein
568
0.66
chr7_127749161_127749327 0.53 ENSG00000207588
.
27331
0.2
chr2_99087882_99088150 0.52 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
26603
0.2
chr1_224567635_224567940 0.52 ENSG00000266618
.
18226
0.14
chr8_125109940_125110091 0.52 FER1L6-AS2
FER1L6 antisense RNA 2
36982
0.16
chr6_15264518_15264669 0.52 JARID2
jumonji, AT rich interactive domain 2
15450
0.18
chr1_45582602_45582826 0.51 ENSG00000264650
.
83022
0.07
chr22_40353121_40353295 0.51 RP3-370M22.8

3193
0.22
chr6_18473762_18473986 0.51 ENSG00000238458
.
71591
0.11
chr8_38820431_38820835 0.51 CTD-2544N14.3

9897
0.15
chr1_173329567_173329718 0.51 ENSG00000251817
.
79426
0.09
chr6_6386883_6387051 0.51 F13A1
coagulation factor XIII, A1 polypeptide
65721
0.13
chr2_122464845_122465052 0.51 ENSG00000238341
.
1315
0.43
chr13_77588295_77588904 0.51 FBXL3
F-box and leucine-rich repeat protein 3
12686
0.17
chr2_202050054_202050758 0.51 CASP10
caspase 10, apoptosis-related cysteine peptidase
2488
0.23
chr3_139360250_139360401 0.51 ENSG00000244692
.
31544
0.15
chr1_160680410_160680561 0.51 CD48
CD48 molecule
1108
0.46
chr1_35384381_35384539 0.50 DLGAP3
discs, large (Drosophila) homolog-associated protein 3
10726
0.15
chr1_100904323_100904474 0.50 RP5-837M10.4

47155
0.13
chr9_117136205_117136760 0.50 AKNA
AT-hook transcription factor
2762
0.28
chrX_118814971_118815179 0.50 SEPT6
septin 6
11717
0.17
chr17_15493735_15493905 0.50 CDRT1
CMT1A duplicated region transcript 1
2902
0.18
chr11_68603270_68603629 0.50 CPT1A
carnitine palmitoyltransferase 1A (liver)
3703
0.25
chr10_111973956_111974242 0.50 MXI1
MAX interactor 1, dimerization protein
4110
0.25
chr19_8776883_8777166 0.49 ACTL9
actin-like 9
32148
0.15
chr19_39108320_39108543 0.49 MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
133
0.91
chrX_49135309_49135460 0.49 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
1855
0.18
chrX_13108038_13108679 0.49 FAM9C
family with sequence similarity 9, member C
45557
0.18
chr13_46745351_46745718 0.49 ENSG00000240767
.
1651
0.31
chr21_15824576_15824727 0.49 HSPA13
heat shock protein 70kDa family, member 13
69143
0.11
chr16_16291149_16291300 0.49 RP11-517A5.7

25660
0.14
chr2_36473715_36473976 0.49 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
109224
0.07
chr6_130897423_130897691 0.49 ENSG00000202438
.
2300
0.44
chr6_6704065_6704216 0.49 LY86-AS1
LY86 antisense RNA 1
81136
0.11
chr17_45747944_45748224 0.49 KPNB1
karyopherin (importin) beta 1
2353
0.21
chr10_11224263_11224523 0.49 RP3-323N1.2

11054
0.22
chr1_101472248_101472457 0.49 RP11-421L21.2

11323
0.14
chr7_3107917_3108284 0.49 CARD11
caspase recruitment domain family, member 11
24521
0.21
chr9_92056751_92057221 0.49 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
5588
0.27
chr3_56921995_56922146 0.48 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
28429
0.21
chr20_32642950_32643101 0.48 ENSG00000264616
.
6100
0.19
chr2_174411230_174411381 0.48 CDCA7
cell division cycle associated 7
191705
0.03
chr19_42144419_42144587 0.48 CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
11061
0.14
chr9_100807459_100807611 0.48 NANS
N-acetylneuraminic acid synthase
11486
0.16
chr21_19160149_19160300 0.47 AL109761.5

5581
0.25
chr20_57828942_57829122 0.47 EDN3
endothelin 3
46450
0.15
chr17_1986510_1986661 0.47 RP11-667K14.5

6390
0.11
chr1_168391373_168391682 0.47 ENSG00000207974
.
46765
0.16
chr11_47372727_47372878 0.47 MYBPC3
myosin binding protein C, cardiac
1451
0.27
chr11_46698721_46699134 0.47 ATG13
autophagy related 13
13377
0.12
chr15_88304777_88304928 0.47 NTRK3
neurotrophic tyrosine kinase, receptor, type 3
171469
0.04
chr2_135049910_135050099 0.47 MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
38174
0.2
chr7_149659397_149659548 0.47 ATP6V0E2-AS1
ATP6V0E2 antisense RNA 1
81773
0.08
chr17_47294381_47294729 0.47 ABI3
ABI family, member 3
2370
0.23
chr5_142382840_142383243 0.47 ARHGAP26
Rho GTPase activating protein 26
33720
0.23
chr5_75770152_75770552 0.47 IQGAP2
IQ motif containing GTPase activating protein 2
70103
0.12
chr2_43421170_43421346 0.47 ZFP36L2
ZFP36 ring finger protein-like 2
32490
0.19
chr7_150283826_150284185 0.47 GIMAP4
GTPase, IMAP family member 4
19481
0.17
chr4_101959961_101960259 0.47 EMCN-IT1
EMCN intronic transcript 1 (non-protein coding)
224673
0.02
chr4_55575798_55575949 0.47 KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
51788
0.18
chr7_152149007_152149206 0.47 ENSG00000221454
.
12800
0.19
chr2_98709602_98709753 0.46 VWA3B
von Willebrand factor A domain containing 3B
5978
0.29
chr19_15572483_15572634 0.46 RASAL3
RAS protein activator like 3
2824
0.17
chr20_47386828_47386979 0.46 ENSG00000251876
.
30918
0.21
chr17_61702102_61702289 0.46 MAP3K3
mitogen-activated protein kinase kinase kinase 3
2125
0.26
chr2_85925084_85925258 0.46 GNLY
granulysin
2680
0.2
chr5_118618812_118619065 0.46 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
14489
0.18
chr7_50237356_50237516 0.46 AC020743.2

55017
0.14
chrX_117631877_117632095 0.46 DOCK11
dedicator of cytokinesis 11
2114
0.4
chr12_111241028_111241340 0.46 CCDC63
coiled-coil domain containing 63
43580
0.14
chr9_20228261_20228412 0.46 ENSG00000221744
.
66666
0.13
chr2_143910130_143910379 0.46 RP11-190J23.1

19487
0.22
chr19_35503259_35503609 0.46 GRAMD1A
GRAM domain containing 1A
12074
0.1
chr17_76755866_76756289 0.46 CYTH1
cytohesin 1
22277
0.17
chrX_62781371_62781552 0.46 ENSG00000235437
.
510
0.87
chr16_70452481_70452645 0.46 ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
18022
0.11
chr8_82045273_82045517 0.46 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
21092
0.26
chr7_2139865_2140016 0.46 MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
7403
0.29
chr1_235095923_235096074 0.46 ENSG00000239690
.
56065
0.15
chr7_26410221_26410372 0.45 AC004540.4

5596
0.24
chr6_24859769_24859968 0.45 FAM65B
family with sequence similarity 65, member B
17673
0.17
chr20_21535849_21536000 0.45 NKX2-2
NK2 homeobox 2
41260
0.16
chr2_8625925_8626222 0.45 AC011747.7

189823
0.03
chr7_153831554_153831705 0.45 AC006019.4

38501
0.18
chr1_221878068_221878253 0.45 DUSP10
dual specificity phosphatase 10
32642
0.24
chr7_13948027_13948412 0.45 ETV1
ets variant 1
77847
0.12
chr5_40607789_40608031 0.45 ENSG00000199552
.
47155
0.16
chr4_6958806_6958998 0.45 TBC1D14
TBC1 domain family, member 14
2955
0.19
chr10_22422484_22422726 0.45 EBLN1
endogenous Bornavirus-like nucleoprotein 1
76345
0.1
chr22_30679087_30679350 0.45 GATSL3
GATS protein-like 3
6378
0.1
chr2_198169561_198169772 0.45 ANKRD44-IT1
ANKRD44 intronic transcript 1 (non-protein coding)
2423
0.25
chr10_27825183_27825334 0.45 RAB18
RAB18, member RAS oncogene family
31710
0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:0006154 adenosine catabolic process(GO:0006154)
0.2 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.3 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.6 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 1.0 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.5 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.8 GO:0031060 regulation of histone methylation(GO:0031060)
0.1 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 1.1 GO:0016045 detection of bacterium(GO:0016045)
0.1 0.3 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.1 0.1 GO:0002886 regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.1 0.4 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.3 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.1 0.1 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.1 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.3 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.1 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.1 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.6 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.1 0.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.6 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.1 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 1.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.4 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 0.1 GO:0060685 regulation of prostatic bud formation(GO:0060685)
0.1 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.2 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.4 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:1902019 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:1902624 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0070849 response to epidermal growth factor(GO:0070849)
0.0 0.0 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.3 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.4 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.2 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0098801 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.3 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0060406 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.0 GO:0030852 regulation of granulocyte differentiation(GO:0030852)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0002704 negative regulation of leukocyte mediated immunity(GO:0002704)
0.0 0.0 GO:0045606 positive regulation of epidermal cell differentiation(GO:0045606)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.0 GO:1901184 regulation of epidermal growth factor receptor signaling pathway(GO:0042058) regulation of ERBB signaling pathway(GO:1901184)
0.0 0.0 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0019724 B cell mediated immunity(GO:0019724)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0050685 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0031054 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0034661 ncRNA catabolic process(GO:0034661)
0.0 0.4 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.0 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.0 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.3 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0010921 regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.3 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0072148 epithelial cell fate commitment(GO:0072148)
0.0 0.0 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:0046463 neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.5 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 1.5 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 0.7 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.0 GO:0010575 positive regulation of vascular endothelial growth factor production(GO:0010575)
0.0 0.0 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.7 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0031652 regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.5 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.1 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0048536 spleen development(GO:0048536)
0.0 0.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.0 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.0 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 2.1 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0010907 positive regulation of glucose metabolic process(GO:0010907)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0034250 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0032647 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0021549 cerebellum development(GO:0021549)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0046365 monosaccharide catabolic process(GO:0046365)
0.0 0.1 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 1.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0031343 positive regulation of cell killing(GO:0031343)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.0 GO:0030146 obsolete diuresis(GO:0030146) obsolete natriuresis(GO:0030147)
0.0 0.0 GO:0033032 myeloid cell apoptotic process(GO:0033028) regulation of myeloid cell apoptotic process(GO:0033032)
0.0 0.0 GO:0060669 embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0 0.0 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0072422 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) cell envelope(GO:0030313) periplasmic space(GO:0042597)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.5 GO:0032154 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.7 GO:0005769 early endosome(GO:0005769)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.0 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0047555 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0035586 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 3.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0048019 receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0060589 nucleoside-triphosphatase regulator activity(GO:0060589)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.0 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.5 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.4 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.5 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.0 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME CELL CYCLE CHECKPOINTS Genes involved in Cell Cycle Checkpoints
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins