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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ESRRB_ESRRG

Z-value: 1.61

Motif logo

Transcription factors associated with ESRRB_ESRRG

Gene Symbol	Gene ID	Gene Info
ESRRB Ensembl NCBI GeneCards UniProt	ENSG00000119715.10	estrogen related receptor beta
ESRRG Ensembl NCBI GeneCards UniProt	ENSG00000196482.12	estrogen related receptor gamma

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_76981672_76981824	ESRRB	107867	0.065913	0.55	1.3e-01	Click!
chr14_76918551_76918702	ESRRB	44745	0.170800	0.49	1.8e-01	Click!
chr14_76881096_76881247	ESRRB	7290	0.255414	0.40	2.8e-01	Click!
chr14_77001333_77001484	ESRRB	127527	0.050770	0.39	3.0e-01	Click!
chr14_76997804_76997955	ESRRB	123998	0.053135	0.38	3.1e-01	Click!
chr1_217448110_217448261	ESRRG	137088	0.052919	-0.90	1.0e-03	Click!
chr1_217449127_217449278	ESRRG	138105	0.052251	-0.88	1.8e-03	Click!
chr1_217448334_217448485	ESRRG	137312	0.052771	-0.87	2.1e-03	Click!
chr1_217449425_217449576	ESRRG	138403	0.052058	-0.83	5.9e-03	Click!
chr1_217216787_217216938	ESRRG	33369	0.253994	0.66	5.1e-02	Click!

Activity of the ESRRB_ESRRG motif across conditions

Conditions sorted by the z-value of the ESRRB_ESRRG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_56039749_56039992	3.83	CTCFL	CCCTC-binding factor (zinc finger protein)-like	59443	0.1
chr11_67173408_67173659	2.08	TBC1D10C	TBC1 domain family, member 10C	1873	0.13
chr11_72864714_72865145	1.10	FCHSD2	FCH and double SH3 domains 2	11623	0.2
chr3_16326802_16326964	1.02	OXNAD1	oxidoreductase NAD-binding domain containing 1	16135	0.16
chr6_41170433_41170835	0.93	TREML2	triggering receptor expressed on myeloid cells-like 2	1702	0.26
chr8_131025939_131026245	0.89	FAM49B	family with sequence similarity 49, member B	2559	0.24
chr4_6920362_6920560	0.88	TBC1D14	TBC1 domain family, member 14	8486	0.18
chr17_2726619_2727134	0.85	RAP1GAP2	RAP1 GTPase activating protein 2	27100	0.16
chr6_33775484_33775750	0.85	MLN	motilin	3829	0.22
chr2_113937603_113937798	0.85	AC016683.5		4763	0.16
chr12_7063873_7064421	0.84	PTPN6	protein tyrosine phosphatase, non-receptor type 6	3609	0.07
chr10_126416114_126416281	0.83	FAM53B	family with sequence similarity 53, member B	15342	0.16
chr7_76869055_76869341	0.82	AC073635.5		18242	0.2
chr12_15134400_15134556	0.81	PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	8522	0.18
chr9_130545994_130546281	0.80	CDK9	cyclin-dependent kinase 9	1821	0.16
chr1_26865150_26865301	0.80	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	4378	0.16
chr3_14418676_14418859	0.80	ENSG00000199609	.	17381	0.21
chr6_24939842_24940244	0.79	FAM65B	family with sequence similarity 65, member B	3855	0.28
chr7_151048881_151049036	0.78	NUB1	negative regulator of ubiquitin-like proteins 1	6527	0.16
chr20_20714651_20715009	0.77	ENSG00000264361	.	4544	0.29
chr1_114483922_114484073	0.77	HIPK1	homeodomain interacting protein kinase 1	9770	0.13
chr18_60806585_60806736	0.77	RP11-299P2.1		11893	0.25
chr12_31986291_31986442	0.77	ENSG00000252204	.	22344	0.16
chr18_2967144_2967376	0.75	RP11-737O24.1		244	0.91
chr6_24962302_24962654	0.74	FAM65B	family with sequence similarity 65, member B	26290	0.19
chr9_95792448_95792761	0.73	FGD3	FYVE, RhoGEF and PH domain containing 3	15262	0.18
chr5_57840573_57840724	0.72	CTD-2117L12.1	Uncharacterized protein	13422	0.18
chr12_50064566_50064804	0.72	FMNL3	formin-like 3	36318	0.11
chr4_68441371_68441728	0.71	STAP1	signal transducing adaptor family member 1	17103	0.2
chr17_3864337_3864743	0.71	ATP2A3	ATPase, Ca++ transporting, ubiquitous	3045	0.24
chr19_13993263_13993689	0.71	NANOS3	nanos homolog 3 (Drosophila)	5413	0.09
chr8_21436069_21436236	0.70	ENSG00000266630	.	28643	0.23
chr18_60880832_60881273	0.70	ENSG00000238988	.	19154	0.21
chr1_28318555_28318747	0.69	RP11-460I13.2		31947	0.1
chr2_102239339_102239566	0.69	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	73860	0.12
chr15_78395422_78395756	0.69	SH2D7	SH2 domain containing 7	10662	0.13
chr11_67173722_67173982	0.67	TBC1D10C	TBC1 domain family, member 10C	2192	0.12
chr1_26642939_26643090	0.67	CD52	CD52 molecule	1434	0.25
chr1_228999751_228999959	0.67	RHOU	ras homolog family member U	129031	0.04
chr17_43297507_43297734	0.67	CTD-2020K17.1		79	0.93
chr5_142156918_142157069	0.66	ARHGAP26	Rho GTPase activating protein 26	4711	0.3
chr21_47979710_47980000	0.66	ENSG00000272283	.	24146	0.15
chr1_112018428_112019095	0.66	C1orf162	chromosome 1 open reading frame 162	2270	0.16
chr20_35583518_35583882	0.65	SAMHD1	SAM domain and HD domain 1	3454	0.28
chr16_27210586_27210926	0.65	KDM8	lysine (K)-specific demethylase 8	4051	0.22
chr10_11203289_11203522	0.65	CELF2	CUGBP, Elav-like family member 2	3588	0.26
chr5_150517774_150517925	0.65	ANXA6	annexin A6	3352	0.26
chr17_76757237_76757578	0.64	CYTH1	cytohesin 1	20947	0.17
chr1_206942061_206942212	0.64	IL10	interleukin 10	3703	0.19
chr12_45363108_45363259	0.64	NELL2	NEL-like 2 (chicken)	47552	0.15
chr4_15758963_15759136	0.64	CD38	CD38 molecule	20852	0.19
chr11_118087590_118088000	0.64	AMICA1	adhesion molecule, interacts with CXADR antigen 1	2189	0.24
chr2_234318940_234319134	0.64	DGKD	diacylglycerol kinase, delta 130kDa	22237	0.15
chr8_27263857_27264174	0.63	PTK2B	protein tyrosine kinase 2 beta	9046	0.23
chr1_206942223_206942745	0.62	IL10	interleukin 10	3355	0.2
chr6_14373007_14373158	0.62	ENSG00000238987	.	216389	0.02
chr20_20725126_20725277	0.61	ENSG00000264361	.	5827	0.28
chr8_27262728_27262897	0.61	PTK2B	protein tyrosine kinase 2 beta	7843	0.23
chr19_1073176_1073340	0.60	HMHA1	histocompatibility (minor) HA-1	1746	0.19
chr9_36139739_36139903	0.60	GLIPR2	GLI pathogenesis-related 2	3079	0.25
chr14_52331770_52332050	0.59	GNG2	guanine nucleotide binding protein (G protein), gamma 2	3868	0.25
chr2_68432811_68432962	0.59	ENSG00000216115	.	24172	0.12
chr19_42705324_42705478	0.59	ENSG00000265122	.	8171	0.09
chr20_47352393_47352549	0.59	ENSG00000251876	.	3514	0.35
chr11_128599507_128599754	0.58	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	33712	0.15
chr1_145452429_145452580	0.58	TXNIP	thioredoxin interacting protein	13198	0.1
chr20_1344489_1344952	0.57	RP11-314N13.3		2454	0.22
chr1_42255513_42255703	0.57	ENSG00000264896	.	30796	0.23
chr14_107080930_107081145	0.57	IGHV1-58	immunoglobulin heavy variable 1-58	2168	0.06
chr8_71275992_71276158	0.57	ENSG00000207036	.	6493	0.25
chr1_200984271_200984521	0.57	KIF21B	kinesin family member 21B	8140	0.19
chr5_75705956_75706117	0.57	IQGAP2	IQ motif containing GTPase activating protein 2	5787	0.3
chr22_17701465_17701764	0.57	CECR1	cat eye syndrome chromosome region, candidate 1	1124	0.53
chr5_133560624_133561078	0.57	PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	394	0.54
chr1_12231932_12232095	0.57	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	4953	0.18
chr6_90088731_90088882	0.57	UBE2J1	ubiquitin-conjugating enzyme E2, J1	26239	0.16
chr7_130715778_130716117	0.56	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	21362	0.2
chr12_111842321_111842586	0.56	SH2B3	SH2B adaptor protein 3	1299	0.45
chr12_55382686_55382958	0.56	TESPA1	thymocyte expressed, positive selection associated 1	4292	0.26
chr2_25558574_25558742	0.56	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	6096	0.22
chr10_17469337_17469935	0.56	ST8SIA6-AS1	ST8SIA6 antisense RNA 1	19610	0.17
chr16_69459124_69459339	0.56	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	545	0.72
chr6_35010733_35010884	0.56	TCP11	t-complex 11, testis-specific	78014	0.09
chr22_39843923_39844104	0.55	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	9336	0.15
chr2_32490514_32490792	0.55	NLRC4	NLR family, CARD domain containing 4	148	0.96
chr3_187698200_187698351	0.55	LPP	LIM domain containing preferred translocation partner in lipoma	172797	0.03
chr8_8646250_8646447	0.55	CLDN23	claudin 23	86900	0.08
chr4_40156378_40156529	0.55	RP11-395I6.3		11842	0.19
chr13_41188423_41188902	0.55	FOXO1	forkhead box O1	52072	0.14
chr16_81502646_81502945	0.55	CMIP	c-Maf inducing protein	24020	0.23
chr13_78299657_78299947	0.55	SLAIN1	SLAIN motif family, member 1	6069	0.24
chr15_45008559_45008779	0.54	B2M	beta-2-microglobulin	4954	0.16
chr14_91855068_91855898	0.54	CCDC88C	coiled-coil domain containing 88C	28207	0.19
chr2_190424501_190424725	0.54	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	21000	0.22
chr19_54880893_54881262	0.54	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	981	0.39
chr2_43402387_43402951	0.54	ZFP36L2	ZFP36 ring finger protein-like 2	51079	0.14
chr21_34568332_34568483	0.54	C21orf54	chromosome 21 open reading frame 54	25866	0.13
chr11_12155195_12155639	0.54	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	4518	0.31
chr13_28006578_28006898	0.54	GTF3A	general transcription factor IIIA	2643	0.24
chr4_100776363_100776514	0.54	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	38435	0.15
chr2_131127308_131127459	0.54	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	279	0.89
chr18_9185859_9186010	0.54	ANKRD12	ankyrin repeat domain 12	3550	0.22
chr16_75094649_75094937	0.53	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	43889	0.12
chr8_100875595_100875746	0.53	COX6C	cytochrome c oxidase subunit VIc	29693	0.19
chr12_94518026_94518226	0.53	PLXNC1	plexin C1	24373	0.2
chr16_30176524_30176675	0.53	CORO1A	coronin, actin binding protein, 1A	17549	0.07
chr2_7061705_7061856	0.53	ENSG00000228203	.	2940	0.24
chr17_81074523_81074674	0.53	METRNL	meteorin, glial cell differentiation regulator-like	22604	0.23
chr1_31196900_31197104	0.53	MATN1	matrilin 1, cartilage matrix protein	568	0.66
chr7_127749161_127749327	0.53	ENSG00000207588	.	27331	0.2
chr2_99087882_99088150	0.52	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	26603	0.2
chr1_224567635_224567940	0.52	ENSG00000266618	.	18226	0.14
chr8_125109940_125110091	0.52	FER1L6-AS2	FER1L6 antisense RNA 2	36982	0.16
chr6_15264518_15264669	0.52	JARID2	jumonji, AT rich interactive domain 2	15450	0.18
chr1_45582602_45582826	0.51	ENSG00000264650	.	83022	0.07
chr22_40353121_40353295	0.51	RP3-370M22.8		3193	0.22
chr6_18473762_18473986	0.51	ENSG00000238458	.	71591	0.11
chr8_38820431_38820835	0.51	CTD-2544N14.3		9897	0.15
chr1_173329567_173329718	0.51	ENSG00000251817	.	79426	0.09
chr6_6386883_6387051	0.51	F13A1	coagulation factor XIII, A1 polypeptide	65721	0.13
chr2_122464845_122465052	0.51	ENSG00000238341	.	1315	0.43
chr13_77588295_77588904	0.51	FBXL3	F-box and leucine-rich repeat protein 3	12686	0.17
chr2_202050054_202050758	0.51	CASP10	caspase 10, apoptosis-related cysteine peptidase	2488	0.23
chr3_139360250_139360401	0.51	ENSG00000244692	.	31544	0.15
chr1_160680410_160680561	0.51	CD48	CD48 molecule	1108	0.46
chr1_35384381_35384539	0.50	DLGAP3	discs, large (Drosophila) homolog-associated protein 3	10726	0.15
chr1_100904323_100904474	0.50	RP5-837M10.4		47155	0.13
chr9_117136205_117136760	0.50	AKNA	AT-hook transcription factor	2762	0.28
chrX_118814971_118815179	0.50	SEPT6	septin 6	11717	0.17
chr17_15493735_15493905	0.50	CDRT1	CMT1A duplicated region transcript 1	2902	0.18
chr11_68603270_68603629	0.50	CPT1A	carnitine palmitoyltransferase 1A (liver)	3703	0.25
chr10_111973956_111974242	0.50	MXI1	MAX interactor 1, dimerization protein	4110	0.25
chr19_8776883_8777166	0.49	ACTL9	actin-like 9	32148	0.15
chr19_39108320_39108543	0.49	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	133	0.91
chrX_49135309_49135460	0.49	PPP1R3F	protein phosphatase 1, regulatory subunit 3F	1855	0.18
chrX_13108038_13108679	0.49	FAM9C	family with sequence similarity 9, member C	45557	0.18
chr13_46745351_46745718	0.49	ENSG00000240767	.	1651	0.31
chr21_15824576_15824727	0.49	HSPA13	heat shock protein 70kDa family, member 13	69143	0.11
chr16_16291149_16291300	0.49	RP11-517A5.7		25660	0.14
chr2_36473715_36473976	0.49	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	109224	0.07
chr6_130897423_130897691	0.49	ENSG00000202438	.	2300	0.44
chr6_6704065_6704216	0.49	LY86-AS1	LY86 antisense RNA 1	81136	0.11
chr17_45747944_45748224	0.49	KPNB1	karyopherin (importin) beta 1	2353	0.21
chr10_11224263_11224523	0.49	RP3-323N1.2		11054	0.22
chr1_101472248_101472457	0.49	RP11-421L21.2		11323	0.14
chr7_3107917_3108284	0.49	CARD11	caspase recruitment domain family, member 11	24521	0.21
chr9_92056751_92057221	0.49	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	5588	0.27
chr3_56921995_56922146	0.48	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	28429	0.21
chr20_32642950_32643101	0.48	ENSG00000264616	.	6100	0.19
chr2_174411230_174411381	0.48	CDCA7	cell division cycle associated 7	191705	0.03
chr19_42144419_42144587	0.48	CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	11061	0.14
chr9_100807459_100807611	0.48	NANS	N-acetylneuraminic acid synthase	11486	0.16
chr21_19160149_19160300	0.47	AL109761.5		5581	0.25
chr20_57828942_57829122	0.47	EDN3	endothelin 3	46450	0.15
chr17_1986510_1986661	0.47	RP11-667K14.5		6390	0.11
chr1_168391373_168391682	0.47	ENSG00000207974	.	46765	0.16
chr11_47372727_47372878	0.47	MYBPC3	myosin binding protein C, cardiac	1451	0.27
chr11_46698721_46699134	0.47	ATG13	autophagy related 13	13377	0.12
chr15_88304777_88304928	0.47	NTRK3	neurotrophic tyrosine kinase, receptor, type 3	171469	0.04
chr2_135049910_135050099	0.47	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	38174	0.2
chr7_149659397_149659548	0.47	ATP6V0E2-AS1	ATP6V0E2 antisense RNA 1	81773	0.08
chr17_47294381_47294729	0.47	ABI3	ABI family, member 3	2370	0.23
chr5_142382840_142383243	0.47	ARHGAP26	Rho GTPase activating protein 26	33720	0.23
chr5_75770152_75770552	0.47	IQGAP2	IQ motif containing GTPase activating protein 2	70103	0.12
chr2_43421170_43421346	0.47	ZFP36L2	ZFP36 ring finger protein-like 2	32490	0.19
chr7_150283826_150284185	0.47	GIMAP4	GTPase, IMAP family member 4	19481	0.17
chr4_101959961_101960259	0.47	EMCN-IT1	EMCN intronic transcript 1 (non-protein coding)	224673	0.02
chr4_55575798_55575949	0.47	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	51788	0.18
chr7_152149007_152149206	0.47	ENSG00000221454	.	12800	0.19
chr2_98709602_98709753	0.46	VWA3B	von Willebrand factor A domain containing 3B	5978	0.29
chr19_15572483_15572634	0.46	RASAL3	RAS protein activator like 3	2824	0.17
chr20_47386828_47386979	0.46	ENSG00000251876	.	30918	0.21
chr17_61702102_61702289	0.46	MAP3K3	mitogen-activated protein kinase kinase kinase 3	2125	0.26
chr2_85925084_85925258	0.46	GNLY	granulysin	2680	0.2
chr5_118618812_118619065	0.46	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	14489	0.18
chr7_50237356_50237516	0.46	AC020743.2		55017	0.14
chrX_117631877_117632095	0.46	DOCK11	dedicator of cytokinesis 11	2114	0.4
chr12_111241028_111241340	0.46	CCDC63	coiled-coil domain containing 63	43580	0.14
chr9_20228261_20228412	0.46	ENSG00000221744	.	66666	0.13
chr2_143910130_143910379	0.46	RP11-190J23.1		19487	0.22
chr19_35503259_35503609	0.46	GRAMD1A	GRAM domain containing 1A	12074	0.1
chr17_76755866_76756289	0.46	CYTH1	cytohesin 1	22277	0.17
chrX_62781371_62781552	0.46	ENSG00000235437	.	510	0.87
chr16_70452481_70452645	0.46	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	18022	0.11
chr8_82045273_82045517	0.46	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	21092	0.26
chr7_2139865_2140016	0.46	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7403	0.29
chr1_235095923_235096074	0.46	ENSG00000239690	.	56065	0.15
chr7_26410221_26410372	0.45	AC004540.4		5596	0.24
chr6_24859769_24859968	0.45	FAM65B	family with sequence similarity 65, member B	17673	0.17
chr20_21535849_21536000	0.45	NKX2-2	NK2 homeobox 2	41260	0.16
chr2_8625925_8626222	0.45	AC011747.7		189823	0.03
chr7_153831554_153831705	0.45	AC006019.4		38501	0.18
chr1_221878068_221878253	0.45	DUSP10	dual specificity phosphatase 10	32642	0.24
chr7_13948027_13948412	0.45	ETV1	ets variant 1	77847	0.12
chr5_40607789_40608031	0.45	ENSG00000199552	.	47155	0.16
chr4_6958806_6958998	0.45	TBC1D14	TBC1 domain family, member 14	2955	0.19
chr10_22422484_22422726	0.45	EBLN1	endogenous Bornavirus-like nucleoprotein 1	76345	0.1
chr22_30679087_30679350	0.45	GATSL3	GATS protein-like 3	6378	0.1
chr2_198169561_198169772	0.45	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	2423	0.25
chr10_27825183_27825334	0.45	RAB18	RAB18, member RAS oncogene family	31710	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.4	GO:0006154	adenosine catabolic process(GO:0006154)
0.2	0.6	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.3	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.1	0.6	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.7	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	1.0	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.5	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.3	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.6	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.8	GO:0031060	regulation of histone methylation(GO:0031060)
0.1	0.3	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.4	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.3	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	1.1	GO:0016045	detection of bacterium(GO:0016045)
0.1	0.3	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.1	GO:0002886	regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.1	0.4	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.3	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.1	0.1	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.4	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.1	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.4	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.2	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.3	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.3	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.3	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.1	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.1	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1	0.5	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.4	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.2	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.1	0.6	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.3	GO:0033194	response to hydroperoxide(GO:0033194)
0.1	0.4	GO:0045116	protein neddylation(GO:0045116)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.2	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.6	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.1	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	1.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.4	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.1	0.1	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.1	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.4	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.2	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.3	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.2	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.2	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.4	GO:0000303	response to superoxide(GO:0000303)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.2	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.4	GO:0007512	adult heart development(GO:0007512)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.3	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:1902019	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.2	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.2	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0070849	response to epidermal growth factor(GO:0070849)
0.0	0.0	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.2	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.3	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.3	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.4	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.4	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.3	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.2	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.2	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) plasma membrane long-chain fatty acid transport(GO:0015911)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0098801	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.3	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.3	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.4	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.2	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.3	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0060406	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0	0.0	GO:0030852	regulation of granulocyte differentiation(GO:0030852)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0060535	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.4	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0009595	detection of biotic stimulus(GO:0009595)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0002704	negative regulation of leukocyte mediated immunity(GO:0002704)
0.0	0.0	GO:0045606	positive regulation of epidermal cell differentiation(GO:0045606)
0.0	0.4	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.2	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.3	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.0	GO:1901184	regulation of epidermal growth factor receptor signaling pathway(GO:0042058) regulation of ERBB signaling pathway(GO:1901184)
0.0	0.0	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.5	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.0	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0042441	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0019724	B cell mediated immunity(GO:0019724)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0042992	negative regulation of transcription factor import into nucleus(GO:0042992)
0.0	0.3	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0050685	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.2	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0031054	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.3	GO:0007530	sex determination(GO:0007530)
0.0	0.1	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.2	GO:0034661	ncRNA catabolic process(GO:0034661)
0.0	0.4	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.0	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.3	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0043049	otic placode formation(GO:0043049)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0002437	inflammatory response to antigenic stimulus(GO:0002437)
0.0	0.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.3	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.4	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0010921	regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0046688	response to copper ion(GO:0046688)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.3	GO:0010043	response to zinc ion(GO:0010043)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.4	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.1	GO:0072148	epithelial cell fate commitment(GO:0072148)
0.0	0.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.1	GO:0006301	postreplication repair(GO:0006301)
0.0	0.4	GO:0046463	neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0	0.5	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.2	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.1	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	1.5	GO:0022900	electron transport chain(GO:0022900)
0.0	0.2	GO:0010039	response to iron ion(GO:0010039)
0.0	0.7	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.0	GO:0010575	positive regulation of vascular endothelial growth factor production(GO:0010575)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.7	GO:0006959	humoral immune response(GO:0006959)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.0	GO:0031652	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.5	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0048536	spleen development(GO:0048536)
0.0	0.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.2	GO:0007140	male meiosis(GO:0007140)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.3	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	0.2	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.0	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	2.1	GO:0050776	regulation of immune response(GO:0050776)
0.0	0.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0010907	positive regulation of glucose metabolic process(GO:0010907)
0.0	0.1	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0006119	oxidative phosphorylation(GO:0006119)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.1	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0009452	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0042748	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.2	GO:0034250	positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.0	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0032647	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.2	GO:0021549	cerebellum development(GO:0021549)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0046365	monosaccharide catabolic process(GO:0046365)
0.0	0.1	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	1.8	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	1.1	GO:0006470	protein dephosphorylation(GO:0006470)
0.0	0.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0031343	positive regulation of cell killing(GO:0031343)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0030146	obsolete diuresis(GO:0030146) obsolete natriuresis(GO:0030147)
0.0	0.0	GO:0033032	myeloid cell apoptotic process(GO:0033028) regulation of myeloid cell apoptotic process(GO:0033032)
0.0	0.0	GO:0060669	embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0	0.0	GO:0098781	ncRNA transcription(GO:0098781)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0072422	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.0	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.5	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.3	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.2	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.5	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.7	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) cell envelope(GO:0030313) periplasmic space(GO:0042597)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0038201	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.4	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.3	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.5	GO:0032154	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.2	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.6	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0042825	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0055037	recycling endosome(GO:0055037)
0.0	1.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	1.7	GO:0005769	early endosome(GO:0005769)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.7	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.4	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0030667	secretory granule membrane(GO:0030667)
0.0	1.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.6	GO:0005643	nuclear pore(GO:0005643)
0.0	0.9	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.0	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.5	GO:0008021	synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.5	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1	1.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.4	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.3	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.3	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.4	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.2	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.4	GO:0004568	chitinase activity(GO:0004568)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.4	GO:0050733	RS domain binding(GO:0050733)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.5	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.3	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	2.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.5	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.4	GO:0051378	serotonin binding(GO:0051378)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.2	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	1.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.6	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0047555	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.3	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	2.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.4	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0035586	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) purinergic receptor activity(GO:0035586)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	3.6	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.1	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.4	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0048019	receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.3	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0060589	nucleoside-triphosphatase regulator activity(GO:0060589)
0.0	0.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.4	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0035240	dopamine binding(GO:0035240)
0.0	0.1	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.0	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.4	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.5	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0034617	nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	1.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.8	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	0.5	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	0.9	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.6	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.4	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.4	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.4	PID FOXO PATHWAY	FoxO family signaling
0.0	0.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.0	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	0.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	0.4	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	2.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.4	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.5	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	2.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.5	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.0	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.3	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.0	0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins

Results for ESRRB_ESRRG

Z-value: 1.61

Motif logo

Transcription factors associated with ESRRB_ESRRG

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ESRRB_ESRRG motif across conditions

Conditions sorted by the z-value of the ESRRB_ESRRG motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: