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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ETS1

Z-value: 2.10

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Transcription factors associated with ETS1

Gene Symbol	Gene ID	Gene Info
ETS1 Ensembl NCBI GeneCards UniProt	ENSG00000134954.10	ETS proto-oncogene 1, transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_128343389_128343759	ETS1	31715	0.208641	0.92	4.1e-04	Click!
chr11_128089678_128089829	ETS1	285536	0.013969	-0.91	7.4e-04	Click!
chr11_128372954_128373665	ETS1	1980	0.404356	0.90	8.2e-04	Click!
chr11_128358884_128359147	ETS1	16274	0.239644	0.89	1.4e-03	Click!
chr11_128168877_128169065	ETS1	206318	0.025228	0.88	1.7e-03	Click!

Activity of the ETS1 motif across conditions

Conditions sorted by the z-value of the ETS1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_1158720_1158941	2.34	AC114808.2		2720	0.39
chrY_14336069_14336220	1.29	ENSG00000243980	.	58033	0.15
chr19_49229748_49230219	1.21	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator	7005	0.09
chr8_144287903_144288067	1.14	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	7083	0.15
chr3_67133814_67134089	0.96	KBTBD8	kelch repeat and BTB (POZ) domain containing 8	84602	0.11
chr19_55665192_55665343	0.94	TNNI3	troponin I type 3 (cardiac)	2826	0.11
chr19_55663404_55663555	0.88	TNNT1	troponin T type 1 (skeletal, slow)	2757	0.12
chr13_22656722_22656873	0.84	ENSG00000244197	.	292121	0.01
chrX_56395231_56395532	0.83	KLF8	Kruppel-like factor 8	135901	0.05
chr17_46521887_46522400	0.78	SKAP1	src kinase associated phosphoprotein 1	14562	0.13
chr6_33150940_33151371	0.78	COL11A2	collagen, type XI, alpha 2	9076	0.08
chr8_144286571_144286722	0.77	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	8422	0.15
chr16_50636706_50636926	0.77	RP11-401P9.6		10779	0.16
chr20_1655542_1655700	0.75	ENSG00000242348	.	8615	0.16
chrX_39179559_39179819	0.75	ENSG00000207122	.	239151	0.02
chr14_61972574_61972725	0.72	RP11-47I22.4		23197	0.18
chr4_77952575_77952848	0.72	SEPT11	septin 11	2841	0.31
chr8_144287595_144287746	0.71	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	7398	0.15
chr19_40177456_40177607	0.70	LGALS17A		5458	0.13
chr14_50550738_50550989	0.69	ENSG00000251792	.	2837	0.21
chr8_53706045_53706196	0.67	RB1CC1	RB1-inducible coiled-coil 1	47717	0.16
chr2_1159179_1159342	0.67	AC114808.2		3150	0.36
chr8_820510_820661	0.67	ERICH1-AS1	ERICH1 antisense RNA 1	12613	0.29
chrX_4159179_4159330	0.66	ENSG00000264861	.	342287	0.01
chrX_3061337_3061668	0.65	ARSF	arylsulfatase F	76628	0.09
chr4_153176560_153176958	0.65	ENSG00000244544	.	8838	0.23
chr7_45163017_45163202	0.63	TBRG4	transforming growth factor beta regulator 4	11463	0.12
chr16_3860194_3860465	0.62	CREBBP	CREB binding protein	29461	0.18
chr15_89180272_89180496	0.60	ISG20	interferon stimulated exonuclease gene 20kDa	1000	0.5
chrY_19194240_19194391	0.59	ENSG00000252315	.	475429	0.01
chrY_14334178_14334329	0.59	ENSG00000243980	.	59924	0.15
chr15_92497720_92497964	0.59	SLCO3A1	solute carrier organic anion transporter family, member 3A1	100491	0.08
chr9_129925727_129925911	0.59	ANGPTL2	angiopoietin-like 2	40657	0.13
chr14_22989891_22990042	0.59	TRAJ15	T cell receptor alpha joining 15	8614	0.11
chr12_45226034_45226185	0.58	NELL2	NEL-like 2 (chicken)	43142	0.18
chr11_73719667_73719951	0.58	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	321	0.87
chr6_139486702_139487008	0.58	HECA	headcase homolog (Drosophila)	30606	0.19
chr8_135355486_135355637	0.57	ZFAT	zinc finger and AT hook domain containing	166864	0.04
chrY_19182245_19182396	0.57	ENSG00000252315	.	487424	0.01
chr14_23007323_23007502	0.57	TRAJ15	T cell receptor alpha joining 15	8832	0.11
chrX_2546999_2547150	0.57	CD99P1	CD99 molecule pseudogene 1	19618	0.22
chr19_36203313_36203562	0.57	ZBTB32	zinc finger and BTB domain containing 32	393	0.65
chrY_14334525_14334676	0.57	ENSG00000243980	.	59577	0.15
chr1_30665971_30666122	0.56	ENSG00000222787	.	308297	0.01
chr6_12149127_12149412	0.56	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	23290	0.26
chr15_59519587_59519738	0.55	MYO1E	myosin IE	127	0.94
chr4_53983291_53983444	0.55	ENSG00000207385	.	148367	0.04
chr11_113236747_113236898	0.55	RP11-159N11.4		2378	0.24
chr12_39725210_39725597	0.55	KIF21A	kinesin family member 21A	726	0.8
chr14_23370090_23370308	0.55	RBM23	RNA binding motif protein 23	1251	0.23
chr2_235276963_235277114	0.54	ARL4C	ADP-ribosylation factor-like 4C	128206	0.06
chr1_114882050_114882323	0.54	TRIM33	tripartite motif containing 33	123672	0.05
chr9_112732229_112732403	0.54	AKAP2	A kinase (PRKA) anchor protein 2	78562	0.1
chr1_204048906_204049578	0.54	SOX13	SRY (sex determining region Y)-box 13	1985	0.32
chr13_40845062_40845224	0.54	ENSG00000207458	.	44179	0.2
chr5_139511455_139511671	0.53	IGIP	IgA-inducing protein	6042	0.15
chr9_131660620_131660924	0.53	LRRC8A	leucine rich repeat containing 8 family, member A	15991	0.11
chr4_7882456_7882620	0.53	AFAP1	actin filament associated protein 1	8498	0.24
chr21_43835004_43835249	0.53	ENSG00000252619	.	2576	0.2
chr9_114748376_114748527	0.53	ENSG00000222356	.	10568	0.2
chr10_112295683_112296070	0.53	SMC3	structural maintenance of chromosomes 3	31573	0.13
chr10_75508861_75509118	0.53	SEC24C	SEC24 family member C	4831	0.09
chr20_1642138_1642418	0.52	SIRPG	signal-regulatory protein gamma	3853	0.18
chr17_45940314_45940519	0.52	SP6	Sp6 transcription factor	7176	0.11
chr17_78623559_78624229	0.52	RPTOR	regulatory associated protein of MTOR, complex 1	104626	0.06
chr14_61645224_61645375	0.51	PRKCH	protein kinase C, eta	8978	0.26
chr8_144108964_144109140	0.50	LY6E	lymphocyte antigen 6 complex, locus E	9078	0.17
chr9_31323752_31324057	0.50	ENSG00000211510	.	549678	0.0
chr5_10786958_10787253	0.50	CTD-2154B17.4		19369	0.22
chr14_99449157_99449308	0.49	AL162151.4		175521	0.03
chr7_150635354_150635936	0.49	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	17349	0.15
chr14_105131813_105132248	0.49	ENSG00000265291	.	12056	0.14
chr4_38308242_38308393	0.49	ENSG00000221495	.	68083	0.14
chr13_45942290_45942441	0.48	TPT1-AS1	TPT1 antisense RNA 1	1729	0.27
chr11_73943410_73943711	0.48	PPME1	protein phosphatase methylesterase 1	1730	0.33
chr14_66316219_66316587	0.48	CTD-2014B16.3	Uncharacterized protein	154838	0.04
chr8_101423313_101423962	0.48	ENSG00000265599	.	28646	0.17
chr14_98477273_98477437	0.48	C14orf64	chromosome 14 open reading frame 64	32894	0.25
chr7_5588809_5589293	0.47	CTB-161C1.1		7311	0.13
chr19_18589481_18589960	0.47	ELL	elongation factor RNA polymerase II	2977	0.14
chrY_19190221_19190372	0.47	ENSG00000252315	.	479448	0.01
chr5_133462716_133463173	0.46	TCF7	transcription factor 7 (T-cell specific, HMG-box)	3635	0.26
chr15_74234171_74234521	0.46	LOXL1-AS1	LOXL1 antisense RNA 1	13757	0.14
chr2_228683348_228683499	0.46	CCL20	chemokine (C-C motif) ligand 20	4853	0.24
chr11_6693256_6693542	0.46	MRPL17	mitochondrial ribosomal protein L17	11148	0.1
chr1_109796466_109796994	0.46	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2	4089	0.18
chr1_40154209_40154360	0.46	HPCAL4	hippocalcin like 4	3077	0.16
chr11_129758569_129758720	0.46	NFRKB	nuclear factor related to kappaB binding protein	4127	0.27
chr12_133449443_133449594	0.45	CHFR	checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase	14600	0.14
chr13_94979866_94980068	0.45	ENSG00000212057	.	137677	0.05
chr15_100651986_100652137	0.45	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	2749	0.28
chr19_47323996_47324533	0.45	AP2S1	adaptor-related protein complex 2, sigma 1 subunit	25141	0.12
chr8_21435381_21435532	0.45	ENSG00000266630	.	27947	0.23
chr22_20885131_20885321	0.45	MED15	mediator complex subunit 15	6664	0.13
chr20_13209551_13209702	0.45	ISM1	isthmin 1, angiogenesis inhibitor	7208	0.2
chr3_130248087_130248238	0.45	COL6A6	collagen, type VI, alpha 6	31016	0.21
chr1_47323240_47323579	0.44	CYP4Z2P	cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene	42697	0.13
chr17_76311998_76312160	0.44	SOCS3	suppressor of cytokine signaling 3	44076	0.1
chrY_19158929_19159080	0.44	ENSG00000252315	.	510740	0.0
chr4_99443439_99443625	0.44	RP11-724M22.1		26017	0.24
chr8_11355176_11355492	0.44	BLK	B lymphoid tyrosine kinase	3435	0.2
chr20_37637617_37637828	0.44	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	12794	0.23
chr9_134542234_134542385	0.44	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	40974	0.15
chr3_70890218_70890369	0.43	ENSG00000206939	.	32792	0.2
chr12_51787723_51788019	0.43	GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	1220	0.39
chr4_1244607_1244758	0.43	CTBP1-AS2	CTBP1 antisense RNA 2 (head to head)	368	0.72
chr12_116918222_116918535	0.43	ENSG00000264037	.	52255	0.15
chr16_4127160_4127311	0.43	ADCY9	adenylate cyclase 9	36792	0.15
chr1_246187527_246187678	0.43	RP11-83A16.1		9251	0.28
chr2_86676643_86676794	0.43	KDM3A	lysine (K)-specific demethylase 3A	7547	0.21
chr17_5291898_5292079	0.43	RABEP1	rabaptin, RAB GTPase binding effector protein 1	11482	0.12
chr1_2949260_2949411	0.43	ACTRT2	actin-related protein T2	11289	0.2
chr1_8427807_8428006	0.43	RERE	arginine-glutamic acid dipeptide (RE) repeats	3008	0.25
chr13_78596428_78596740	0.43	RNF219-AS1	RNF219 antisense RNA 1	32396	0.21
chr11_73679875_73680026	0.43	RP11-167N4.2		1382	0.33
chr20_61958160_61958405	0.42	COL20A1	collagen, type XX, alpha 1	6831	0.12
chr19_2533837_2533988	0.42	ENSG00000252962	.	30773	0.13
chr9_2764569_2764720	0.42	KCNV2	potassium channel, subfamily V, member 2	47142	0.16
chr11_6436078_6436543	0.42	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	3990	0.16
chr3_52039773_52040512	0.42	RPL29	ribosomal protein L29	10184	0.09
chrX_70857558_70857946	0.42	ENSG00000264855	.	12047	0.19
chr7_148618574_148618725	0.42	ENSG00000252310	.	19931	0.13
chr11_14588887_14589038	0.42	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	46720	0.15
chr10_3851430_3851929	0.42	KLF6	Kruppel-like factor 6	24206	0.21
chr20_4664069_4664220	0.42	PRNP	prion protein	2738	0.31
chr6_42661436_42661728	0.42	PRPH2	peripherin 2 (retinal degeneration, slow)	28730	0.14
chr6_16323983_16324134	0.41	GMPR	guanosine monophosphate reductase	85247	0.08
chr11_2949258_2949807	0.41	PHLDA2	pleckstrin homology-like domain, family A, member 2	1153	0.37
chr14_55871045_55871206	0.41	ATG14	autophagy related 14	7451	0.23
chr15_69353313_69353464	0.41	RP11-809H16.4		17483	0.2
chr7_97878450_97878874	0.41	TECPR1	tectonin beta-propeller repeat containing 1	2577	0.27
chr15_75889709_75889860	0.41	PTPN9	protein tyrosine phosphatase, non-receptor type 9	18154	0.11
chr14_98658948_98659099	0.41	ENSG00000222066	.	139064	0.05
chr8_131147186_131147447	0.41	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	16548	0.2
chr19_49976065_49976305	0.41	FLT3LG	fms-related tyrosine kinase 3 ligand	1300	0.17
chr4_38491892_38492151	0.41	RP11-617D20.1		134175	0.05
chr8_22406945_22407789	0.41	SORBS3	sorbin and SH3 domain containing 3	1841	0.21
chr12_117317698_117317992	0.41	HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	1048	0.59
chr11_63616786_63616937	0.40	MARK2	MAP/microtubule affinity-regulating kinase 2	574	0.69
chrX_9535016_9535415	0.40	TBL1X	transducin (beta)-like 1X-linked	32232	0.24
chr12_46637271_46637422	0.40	SLC38A1	solute carrier family 38, member 1	24138	0.26
chr5_168307063_168307214	0.40	ENSG00000202345	.	88635	0.08
chr17_73868550_73868930	0.40	TRIM47	tripartite motif containing 47	2233	0.14
chr21_32655325_32655694	0.40	TIAM1	T-cell lymphoma invasion and metastasis 1	6426	0.32
chr4_40234256_40234407	0.40	RHOH	ras homolog family member H	32367	0.17
chr3_51475768_51475919	0.40	VPRBP	Vpr (HIV-1) binding protein	8179	0.22
chr7_17314165_17314584	0.40	AC003075.4		6553	0.26
chr9_140356468_140356619	0.40	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	2757	0.17
chr16_66333348_66333658	0.40	ENSG00000201999	.	2209	0.38
chr11_76793287_76793438	0.40	CAPN5	calpain 5	15322	0.16
chr10_87372001_87372388	0.40	RP11-93H12.2		7044	0.23
chr16_56581660_56581824	0.39	MT4	metallothionein 4	17219	0.11
chr1_9460580_9460928	0.39	ENSG00000252956	.	37083	0.16
chr10_69776442_69776593	0.39	ENSG00000266467	.	8743	0.19
chr3_111721427_111721798	0.39	TAGLN3	transgelin 3	1993	0.31
chr8_81288726_81288959	0.39	ENSG00000252884	.	28909	0.19
chr14_103274371_103274522	0.39	ENSG00000238853	.	18518	0.16
chr5_121489344_121489733	0.39	CTC-441N14.2		1013	0.49
chr2_69536516_69536759	0.39	ENSG00000252250	.	25095	0.2
chr7_131055309_131055771	0.39	ENSG00000236753	.	42559	0.17
chr6_119212328_119212531	0.39	ASF1A	anti-silencing function 1A histone chaperone	2955	0.29
chr1_230220237_230220388	0.39	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	17294	0.23
chr1_200854970_200855201	0.39	C1orf106	chromosome 1 open reading frame 106	5091	0.19
chr2_84904894_84905045	0.39	DNAH6	dynein, axonemal, heavy chain 6	19538	0.25
chr2_196444721_196445061	0.39	SLC39A10	solute carrier family 39 (zinc transporter), member 10	4190	0.31
chr16_66441942_66442542	0.39	CDH5	cadherin 5, type 2 (vascular endothelium)	12884	0.17
chr6_35361852_35362058	0.39	PPARD	peroxisome proliferator-activated receptor delta	51553	0.11
chr4_6179526_6179776	0.39	JAKMIP1	janus kinase and microtubule interacting protein 1	16693	0.26
chr16_11181303_11181872	0.39	RP11-66H6.3		16628	0.18
chr12_46285760_46285911	0.39	ENSG00000265093	.	18023	0.21
chr1_240830046_240830197	0.38	ENSG00000251750	.	13454	0.19
chr19_39148084_39148524	0.38	ACTN4	actinin, alpha 4	9926	0.12
chr16_50357744_50357895	0.38	BRD7	bromodomain containing 7	3531	0.22
chr16_25308423_25308574	0.38	ZKSCAN2	zinc finger with KRAB and SCAN domains 2	39246	0.16
chr17_79065357_79065551	0.38	BAIAP2	BAI1-associated protein 2	5193	0.13
chr7_111200839_111201058	0.38	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	1032	0.7
chr6_91173247_91173422	0.38	ENSG00000252676	.	16843	0.27
chr10_71122163_71122531	0.38	ENSG00000221774	.	1050	0.54
chr7_1737227_1737378	0.38	AC074389.6	LOC401296 protein; Uncharacterized protein	3341	0.25
chr1_117555339_117555490	0.38	CD101	CD101 molecule	10980	0.16
chr12_68849860_68850057	0.38	MDM1	Mdm1 nuclear protein homolog (mouse)	123797	0.05
chr1_166054561_166054712	0.38	RP11-375H19.2		4216	0.21
chr11_63719762_63720286	0.37	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	13304	0.1
chr7_127378987_127379138	0.37	SND1	staphylococcal nuclease and tudor domain containing 1	86828	0.08
chr1_2431468_2431763	0.37	RP3-395M20.3		5697	0.11
chr10_64966888_64967155	0.37	JMJD1C	jumonji domain containing 1C	464	0.87
chr3_179283487_179283638	0.37	ACTL6A	actin-like 6A	2815	0.2
chr2_174800203_174800598	0.37	SP3	Sp3 transcription factor	28547	0.26
chr20_21535618_21535782	0.37	NKX2-2	NK2 homeobox 2	41036	0.16
chrY_2497032_2497183	0.37	ENSG00000251841	.	155683	0.04
chr18_46482475_46482626	0.37	SMAD7	SMAD family member 7	5469	0.26
chr13_97902613_97903051	0.37	MBNL2	muscleblind-like splicing regulator 2	25626	0.25
chr7_2750642_2751031	0.37	AMZ1	archaelysin family metallopeptidase 1	23000	0.18
chr21_43619697_43619986	0.37	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	42	0.98
chr4_88024806_88024957	0.37	AFF1	AF4/FMR2 family, member 1	54077	0.15
chr14_70222082_70222233	0.37	SRSF5	serine/arginine-rich splicing factor 5	11653	0.21
chr3_29342945_29343096	0.37	RBMS3-AS3	RBMS3 antisense RNA 3	10803	0.23
chrY_19194826_19194977	0.37	ENSG00000252315	.	474843	0.01
chr8_129871332_129871483	0.37	ENSG00000221351	.	39367	0.23
chr16_50429807_50429958	0.36	BRD7	bromodomain containing 7	27037	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ETS1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.5	GO:0071503	response to heparin(GO:0071503)
0.1	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.4	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.3	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.6	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.6	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.7	GO:0000303	response to superoxide(GO:0000303)
0.1	0.4	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	0.1	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.1	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.3	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.3	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.3	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	0.2	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0098754	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) detoxification(GO:0098754)
0.0	0.1	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.2	GO:0022009	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.4	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.4	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.2	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.2	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.2	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.2	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.3	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.1	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.2	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.4	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0034653	isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.2	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.0	GO:0031065	regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.0	0.1	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.0	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:2000051	planar cell polarity pathway involved in axis elongation(GO:0003402) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0034651	cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.4	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0090493	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0031340	regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.0	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0060177	regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.0	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.2	GO:0010458	exit from mitosis(GO:0010458)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.3	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.5	GO:0030048	actin filament-based movement(GO:0030048)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976) activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0051350	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.0	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883) sodium ion homeostasis(GO:0055078)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0033059	cellular pigmentation(GO:0033059)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.0	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0050856	regulation of T cell receptor signaling pathway(GO:0050856)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.5	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0099518	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.3	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031904	endosome lumen(GO:0031904)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.3	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.4	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) endoribonuclease complex(GO:1902555)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.0	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.0	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.6	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031014	troponin T binding(GO:0031014)
0.1	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.4	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.4	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.5	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.4	GO:0043531	ADP binding(GO:0043531)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	1.1	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.4	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.3	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
1.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4	PID ARF 3PATHWAY	Arf1 pathway
0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	PID EPO PATHWAY	EPO signaling pathway
0.2	PID MYC PATHWAY	C-MYC pathway
0.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.4	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.3	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.3	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis

Results for ETS1

Z-value: 2.10

Motif logo

Transcription factors associated with ETS1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ETS1 motif across conditions

Conditions sorted by the z-value of the ETS1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ETS1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: