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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ETV4_ETS2

Z-value: 1.74

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Transcription factors associated with ETV4_ETS2

Gene Symbol	Gene ID	Gene Info
ETV4 Ensembl NCBI GeneCards UniProt	ENSG00000175832.8	ETV4
ETS2 Ensembl NCBI GeneCards UniProt	ENSG00000157557.7	ETS2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ETS2	chr21_40211457_40211608	29972	0.213816	-0.91	7.9e-04	Click!
ETS2	chr21_40107907_40108234	69161	0.118681	0.90	1.0e-03	Click!
ETS2	chr21_40191799_40191950	10314	0.279069	-0.88	1.9e-03	Click!
ETS2	chr21_40145907_40146058	31249	0.225971	-0.88	1.9e-03	Click!
ETS2	chr21_40113815_40114007	63320	0.132035	0.87	2.1e-03	Click!
ETV4	chr17_41657127_41657278	214	0.927968	-0.92	4.9e-04	Click!
ETV4	chr17_41668721_41668956	11850	0.164874	-0.89	1.4e-03	Click!
ETV4	chr17_41614167_41614318	6440	0.145288	-0.87	2.3e-03	Click!
ETV4	chr17_41665619_41665770	8706	0.170606	-0.84	4.9e-03	Click!
ETV4	chr17_41669061_41669212	12148	0.164406	-0.83	5.3e-03	Click!

Activity of the ETV4_ETS2 motif across conditions

Conditions sorted by the z-value of the ETV4_ETS2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_66344432_66344613	0.80	ARSG	arylsulfatase G	56863	0.1
chr20_47426342_47426648	0.79	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	17925	0.25
chr9_95857166_95857358	0.55	RP11-274J16.5		549	0.64
chr1_198648783_198649296	0.52	RP11-553K8.5		12849	0.25
chr2_1159179_1159342	0.52	AC114808.2		3150	0.36
chr14_22698792_22699002	0.51	ENSG00000238634	.	88010	0.08
chr1_27945115_27945319	0.49	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	5356	0.15
chr10_1748865_1749168	0.48	ADARB2	adenosine deaminase, RNA-specific, B2 (non-functional)	30654	0.25
chr17_3876410_3876657	0.48	ATP2A3	ATPase, Ca++ transporting, ubiquitous	8797	0.19
chr3_13462527_13462772	0.47	NUP210	nucleoporin 210kDa	840	0.69
chr3_121992342_121992690	0.46	ENSG00000221474	.	8184	0.17
chr7_50359099_50359391	0.45	IKZF1	IKAROS family zinc finger 1 (Ikaros)	8000	0.29
chr11_1777117_1777382	0.44	CTSD	cathepsin D	1073	0.3
chr2_233637307_233637592	0.44	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13	1334	0.35
chr14_106586968_106587173	0.44	IGHV3-13	immunoglobulin heavy variable 3-13	403	0.55
chr1_231747913_231748254	0.44	LINC00582	long intergenic non-protein coding RNA 582	247	0.93
chr10_75624787_75625518	0.43	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	4540	0.13
chr1_79111221_79111724	0.43	IFI44	interferon-induced protein 44	4044	0.25
chr15_75761353_75761612	0.43	SIN3A	SIN3 transcription regulator family member A	13299	0.17
chr19_42380978_42381662	0.43	CD79A	CD79a molecule, immunoglobulin-associated alpha	30	0.96
chr5_131766860_131767115	0.41	AC116366.5		4581	0.15
chr9_7977098_7977328	0.41	TMEM261	transmembrane protein 261	177146	0.04
chr10_126300419_126300570	0.41	FAM53B-AS1	FAM53B antisense RNA 1	91700	0.07
chr20_37874398_37874627	0.41	ENSG00000211534	.	25671	0.24
chr1_245215119_245215800	0.41	ENSG00000251754	.	8229	0.17
chr4_109022130_109022312	0.41	LEF1	lymphoid enhancer-binding factor 1	65236	0.11
chr11_22679018_22679311	0.40	GAS2	growth arrest-specific 2	8997	0.19
chr5_169755785_169756172	0.40	KCNIP1	Kv channel interacting protein 1	24513	0.17
chr1_65329902_65330534	0.40	RAVER2	ribonucleoprotein, PTB-binding 2	86471	0.09
chr8_125207320_125207810	0.40	FER1L6-AS2	FER1L6 antisense RNA 2	23802	0.22
chr2_231526275_231526495	0.40	CAB39	calcium binding protein 39	51175	0.12
chr17_34617095_34617334	0.40	CCL3L1	chemokine (C-C motif) ligand 3-like 1	8505	0.15
chr9_117129895_117130125	0.39	AKNA	AT-hook transcription factor	9234	0.2
chr9_95845314_95845570	0.38	SUSD3	sushi domain containing 3	5314	0.17
chr3_187767704_187767957	0.38	LPP	LIM domain containing preferred translocation partner in lipoma	103242	0.07
chr3_15332186_15332608	0.38	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	14845	0.14
chr16_17542836_17543247	0.37	XYLT1	xylosyltransferase I	21697	0.29
chr2_43355341_43355494	0.37	ENSG00000207087	.	36785	0.2
chr2_127292142_127292584	0.37	GYPC	glycophorin C (Gerbich blood group)	121146	0.06
chr2_136887722_136888188	0.37	CXCR4	chemokine (C-X-C motif) receptor 4	12220	0.28
chr1_167596920_167597366	0.37	RCSD1	RCSD domain containing 1	2187	0.29
chr15_92638658_92638888	0.37	RP11-24J19.1		76893	0.12
chr9_92039484_92039635	0.37	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	5811	0.27
chr12_94517688_94517977	0.37	PLXNC1	plexin C1	24667	0.2
chr2_43360484_43360742	0.36	ENSG00000207087	.	41981	0.18
chr11_10466387_10466752	0.36	AMPD3	adenosine monophosphate deaminase 3	5299	0.22
chr11_6251311_6251645	0.36	FAM160A2	family with sequence similarity 160, member A2	4368	0.13
chr2_112456540_112456691	0.36	ENSG00000266063	.	72096	0.12
chr6_166747055_166747348	0.36	SFT2D1	SFT2 domain containing 1	8878	0.19
chr6_26478196_26478347	0.35	BTN2A1	butyrophilin, subfamily 2, member A1	12816	0.12
chr19_41808478_41808629	0.35	CCDC97	coiled-coil domain containing 97	7541	0.11
chr8_27226673_27226824	0.35	PTK2B	protein tyrosine kinase 2 beta	11420	0.22
chr7_36325933_36326467	0.35	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	10553	0.18
chr20_56200862_56201087	0.35	ZBP1	Z-DNA binding protein 1	5342	0.25
chr2_231361090_231361274	0.35	SP100	SP100 nuclear antigen	7795	0.21
chr1_226840930_226841348	0.35	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	6232	0.23
chr22_50319499_50319650	0.34	CRELD2	cysteine-rich with EGF-like domains 2	7193	0.17
chr5_176722952_176723252	0.34	RAB24	RAB24, member RAS oncogene family	7605	0.12
chr2_69062364_69062558	0.34	AC097495.2		325	0.9
chr7_127751189_127751374	0.34	ENSG00000207588	.	29368	0.19
chr7_156689439_156689590	0.34	LMBR1	limb development membrane protein 1	3590	0.25
chr20_57757764_57758007	0.34	ZNF831	zinc finger protein 831	8190	0.26
chr2_99079929_99080200	0.33	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	18651	0.22
chr10_30783492_30783645	0.33	MAP3K8	mitogen-activated protein kinase kinase kinase 8	55817	0.12
chr14_52334181_52334332	0.33	GNG2	guanine nucleotide binding protein (G protein), gamma 2	6214	0.22
chr10_126393776_126393927	0.33	FAM53B-AS1	FAM53B antisense RNA 1	1098	0.53
chr2_106392462_106392714	0.33	NCK2	NCK adaptor protein 2	30400	0.23
chr14_35809472_35809661	0.33	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	29527	0.18
chr12_9918241_9918423	0.33	CD69	CD69 molecule	4835	0.18
chr3_123242131_123242282	0.33	PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	22666	0.2
chr14_106453805_106454306	0.32	IGHV1-2	immunoglobulin heavy variable 1-2	885	0.24
chr3_186588899_186589622	0.32	ADIPOQ-AS1	ADIPOQ antisense RNA 1	15348	0.12
chr3_12654461_12654707	0.32	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	1080	0.49
chr1_247570539_247571127	0.32	NLRP3	NLR family, pyrin domain containing 3	8625	0.18
chr14_55321009_55321209	0.32	ENSG00000252019	.	4824	0.23
chr9_14994733_14994933	0.32	RP11-54D18.3		53226	0.15
chr1_233114549_233114766	0.31	NTPCR	nucleoside-triphosphatase, cancer-related	28271	0.23
chr11_45002209_45002427	0.31	TP53I11	tumor protein p53 inducible protein 11	29710	0.22
chr21_36080496_36080697	0.31	AP000330.8		37458	0.17
chr11_117922812_117923152	0.31	ENSG00000272075	.	14970	0.15
chr8_52912939_52913092	0.31	RP11-110G21.1		100721	0.07
chr19_15625593_15626001	0.31	CYP4F22	cytochrome P450, family 4, subfamily F, polypeptide 22	6493	0.15
chr14_51278970_51279194	0.31	RP11-286O18.1		9516	0.15
chr19_33648919_33649221	0.31	ENSG00000264355	.	18908	0.12
chr10_73514684_73515259	0.31	C10orf54	chromosome 10 open reading frame 54	2416	0.29
chr19_10982774_10983002	0.31	CARM1	coactivator-associated arginine methyltransferase 1	509	0.7
chr7_140058363_140058567	0.31	SLC37A3	solute carrier family 37, member 3	6565	0.15
chr1_209921995_209922325	0.31	TRAF3IP3	TRAF3 interacting protein 3	7217	0.14
chr1_229193442_229194258	0.31	RP5-1061H20.5		169459	0.03
chr10_51504373_51504582	0.30	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	18150	0.18
chr4_13616920_13617103	0.30	BOD1L1	biorientation of chromosomes in cell division 1-like 1	12336	0.19
chr14_101718457_101718677	0.30	ENSG00000206761	.	106535	0.03
chr21_34616709_34617146	0.30	AP000295.9		2152	0.24
chr8_81288726_81288959	0.30	ENSG00000252884	.	28909	0.19
chr19_7783538_7783845	0.30	CLEC4G	C-type lectin domain family 4, member G	13366	0.09
chr8_126275118_126275439	0.30	ENSG00000242170	.	7568	0.27
chr10_80825552_80825775	0.30	ZMIZ1-AS1	ZMIZ1 antisense RNA 1	1562	0.44
chr1_156084846_156085321	0.30	LMNA	lamin A/C	570	0.62
chrX_147391899_147392419	0.30	AC002368.4		189976	0.03
chrX_19369143_19369294	0.30	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	4482	0.28
chr1_114422656_114422813	0.30	BCL2L15	BCL2-like 15	7263	0.12
chr1_226900136_226900391	0.30	ITPKB	inositol-trisphosphate 3-kinase B	24896	0.18
chr7_142503625_142503977	0.30	PRSS3P2	protease, serine, 3 pseudogene 2	22670	0.15
chr9_130541716_130542127	0.30	SH2D3C	SH2 domain containing 3C	901	0.36
chr1_212968214_212968462	0.30	TATDN3	TatD DNase domain containing 3	313	0.88
chr8_41890196_41890347	0.29	ENSG00000238966	.	10822	0.2
chr1_26616271_26616515	0.29	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	9780	0.11
chr12_94598358_94598823	0.29	RP11-74K11.2		18770	0.19
chr10_22780969_22781267	0.29	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	99486	0.07
chr16_68108782_68108933	0.29	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	10390	0.1
chr12_94638571_94638798	0.29	PLXNC1	plexin C1	9610	0.18
chr17_55508669_55509100	0.29	ENSG00000263902	.	19322	0.24
chr11_73725373_73725524	0.29	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	4968	0.18
chr11_201596_201747	0.29	RP11-304M2.5		1952	0.16
chr7_150329408_150329559	0.29	GIMAP6	GTPase, IMAP family member 6	10	0.98
chr14_31679580_31679731	0.29	HECTD1	HECT domain containing E3 ubiquitin protein ligase 1	2645	0.24
chr17_2697596_2697803	0.29	RAP1GAP2	RAP1 GTPase activating protein 2	2033	0.3
chrX_65225518_65225769	0.29	RP6-159A1.3		6050	0.22
chr5_176723283_176724082	0.29	RAB24	RAB24, member RAS oncogene family	7025	0.12
chr19_14549826_14550082	0.29	PKN1	protein kinase N1	1118	0.36
chr13_46752398_46752790	0.29	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	3865	0.19
chr11_60931918_60932069	0.29	VPS37C	vacuolar protein sorting 37 homolog C (S. cerevisiae)	2904	0.22
chr1_28582798_28582949	0.29	SESN2	sestrin 2	3165	0.16
chr2_131723685_131723880	0.29	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	35251	0.15
chr1_231750383_231750879	0.29	LINC00582	long intergenic non-protein coding RNA 582	2795	0.27
chr11_6693256_6693542	0.29	MRPL17	mitochondrial ribosomal protein L17	11148	0.1
chr2_87874778_87875151	0.29	ENSG00000265507	.	54310	0.16
chr16_23908409_23908633	0.29	PRKCB	protein kinase C, beta	59977	0.13
chr1_181059966_181060133	0.28	IER5	immediate early response 5	2411	0.34
chr15_52053125_52053320	0.28	CTD-2308G16.1		8540	0.14
chr5_527247_527623	0.28	RP11-310P5.2		2615	0.18
chr2_233083878_233084231	0.28	ENSG00000207626	.	46691	0.14
chr7_6065786_6066227	0.28	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1	177	0.89
chr2_202074008_202074192	0.28	CASP8	caspase 8, apoptosis-related cysteine peptidase	24066	0.14
chr4_184949026_184949285	0.28	STOX2	storkhead box 2	26677	0.21
chr3_188838639_188838790	0.28	TPRG1	tumor protein p63 regulated 1	20804	0.28
chr6_83073756_83074156	0.28	TPBG	trophoblast glycoprotein	5	0.99
chr10_126365162_126365313	0.28	FAM53B-AS1	FAM53B antisense RNA 1	26957	0.19
chr21_46334235_46334386	0.28	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	112	0.94
chr10_78801343_78801560	0.28	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	37831	0.2
chr20_58586927_58587156	0.28	CDH26	cadherin 26	15592	0.2
chrX_70379151_70379501	0.28	NLGN3	neuroligin 3	14614	0.11
chr16_17469640_17470020	0.27	XYLT1	xylosyltransferase I	94908	0.1
chr22_25784908_25785204	0.27	LRP5L	low density lipoprotein receptor-related protein 5-like	7512	0.22
chr21_15922138_15922469	0.27	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	3639	0.29
chr2_136884931_136885082	0.27	CXCR4	chemokine (C-X-C motif) receptor 4	9271	0.29
chr14_104858355_104858716	0.27	ENSG00000222761	.	8850	0.27
chr9_78781333_78781701	0.27	PCSK5	proprotein convertase subtilisin/kexin type 5	22038	0.28
chr4_56263060_56263211	0.27	TMEM165	transmembrane protein 165	1005	0.37
chr9_35618104_35618377	0.27	CD72	CD72 molecule	127	0.91
chr5_138414055_138414601	0.27	SIL1	SIL1 nucleotide exchange factor	35957	0.15
chr6_42358231_42358398	0.27	ENSG00000221252	.	21820	0.2
chr2_99271555_99271876	0.27	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	8221	0.22
chr3_177661794_177662251	0.27	ENSG00000199858	.	63545	0.15
chr6_70526539_70526715	0.27	LMBRD1	LMBR1 domain containing 1	19624	0.25
chr7_1089147_1089438	0.27	GPR146	G protein-coupled receptor 146	5080	0.11
chr7_149561438_149561589	0.27	RP4-751H13.7		1932	0.29
chr16_75139857_75140251	0.27	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	1372	0.36
chr16_30949063_30949295	0.27	FBXL19	F-box and leucine-rich repeat protein 19	4517	0.09
chr6_37939838_37940078	0.27	ZFAND3	zinc finger, AN1-type domain 3	42223	0.17
chr9_92096327_92096478	0.27	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1597	0.45
chr12_109714684_109714945	0.27	FOXN4	forkhead box N4	9714	0.21
chr16_21627363_21627564	0.27	METTL9	methyltransferase like 9	1756	0.25
chr4_3198531_3198813	0.27	HTT	huntingtin	36583	0.16
chr7_29284217_29284368	0.27	AC004593.3		35706	0.16
chr9_92077290_92077553	0.27	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	6553	0.25
chr1_33448728_33449007	0.27	RP1-117O3.2		3809	0.17
chr10_97518313_97518724	0.27	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	2804	0.31
chr22_29204880_29205031	0.27	CTA-292E10.8		5947	0.15
chr20_35272363_35272546	0.27	SLA2	Src-like-adaptor 2	1830	0.26
chr18_46407234_46407394	0.27	RP11-484L8.1		46173	0.16
chr11_73721865_73722409	0.27	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	1657	0.32
chr2_8612472_8612957	0.26	AC011747.7		203182	0.03
chr15_51368814_51368965	0.26	RP11-394B5.2		7106	0.24
chr12_7499136_7499301	0.26	CD163L1	CD163 molecule-like 1	22348	0.18
chr6_42000091_42000640	0.26	ENSG00000206875	.	14113	0.15
chr21_48025165_48025458	0.26	S100B	S100 calcium binding protein B	190	0.95
chr10_73845525_73845681	0.26	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	2483	0.34
chr1_40309344_40309495	0.26	ENSG00000202222	.	37931	0.09
chr9_134454368_134454603	0.26	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	42740	0.12
chr6_42343431_42343582	0.26	ENSG00000221252	.	36628	0.17
chr3_195826753_195826904	0.26	TFRC	transferrin receptor	17768	0.16
chr10_3709087_3709289	0.26	RP11-184A2.3		84071	0.1
chr7_149562206_149562836	0.26	RP4-751H13.7		2940	0.22
chr8_125210409_125210588	0.26	FER1L6-AS2	FER1L6 antisense RNA 2	26735	0.21
chr19_6766080_6766650	0.26	SH2D3A	SH2 domain containing 3A	1081	0.38
chr15_50554636_50555120	0.26	HDC	histidine decarboxylase	748	0.6
chr4_169427075_169427226	0.26	PALLD	palladin, cytoskeletal associated protein	5569	0.22
chr1_246187527_246187678	0.26	RP11-83A16.1		9251	0.28
chr7_101784523_101784872	0.26	ENSG00000252824	.	52747	0.12
chr11_69009932_69010222	0.26	MYEOV	myeloma overexpressed	51528	0.15
chr1_211483375_211483526	0.26	TRAF5	TNF receptor-associated factor 5	16507	0.21
chr19_55219671_55220067	0.26	ENSG00000266427	.	1861	0.19
chr9_137287207_137287358	0.26	RXRA	retinoid X receptor, alpha	11146	0.23
chr8_54794402_54794553	0.25	RGS20	regulator of G-protein signaling 20	1023	0.52
chr2_8451327_8451593	0.25	AC011747.7		364436	0.01
chr3_16884759_16884923	0.25	PLCL2	phospholipase C-like 2	41611	0.19
chr18_43580594_43580948	0.25	ENSG00000222179	.	10860	0.19
chr11_117841509_117841660	0.25	IL10RA	interleukin 10 receptor, alpha	15479	0.17
chr16_3121743_3122141	0.25	ENSG00000252561	.	2418	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV4_ETS2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.3	GO:0009405	pathogenesis(GO:0009405)
0.1	0.4	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.4	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.1	GO:0002666	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.2	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.9	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.3	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0002645	regulation of tolerance induction(GO:0002643) positive regulation of tolerance induction(GO:0002645)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.5	GO:0000303	response to superoxide(GO:0000303)
0.0	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.1	GO:0015809	arginine transport(GO:0015809)
0.0	0.4	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.3	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.0	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.2	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.1	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0043367	CD4-positive, alpha-beta T cell activation(GO:0035710) CD4-positive, alpha-beta T cell differentiation(GO:0043367)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0042832	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.2	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0051132	NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0061054	dermatome development(GO:0061054)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.2	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.5	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.2	GO:0002920	regulation of humoral immune response(GO:0002920)
0.0	0.1	GO:0002724	T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0098543	detection of other organism(GO:0098543)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.5	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.2	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0009595	detection of biotic stimulus(GO:0009595)
0.0	0.6	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0006266	DNA ligation(GO:0006266)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0052803	histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0031060	regulation of histone methylation(GO:0031060)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.4	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0072193	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0032747	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:1903726	negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.0	GO:0032847	regulation of cellular pH reduction(GO:0032847)
0.0	0.1	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.0	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0015669	gas transport(GO:0015669)
0.0	0.0	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0045069	regulation of viral genome replication(GO:0045069)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0003416	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.2	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	2.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.4	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.2	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.4	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.7	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.0	GO:0008493	tetracycline transporter activity(GO:0008493)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.2	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.0	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.6	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.7	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.7	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.6	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.5	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC