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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ETV4_ETS2

Z-value: 1.74

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Transcription factors associated with ETV4_ETS2

Gene Symbol Gene ID Gene Info
ENSG00000175832.8 ETS variant transcription factor 4
ENSG00000157557.7 ETS proto-oncogene 2, transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr21_40211457_40211608ETS2299720.213816-0.917.9e-04Click!
chr21_40107907_40108234ETS2691610.1186810.901.0e-03Click!
chr21_40191799_40191950ETS2103140.279069-0.881.9e-03Click!
chr21_40145907_40146058ETS2312490.225971-0.881.9e-03Click!
chr21_40113815_40114007ETS2633200.1320350.872.1e-03Click!
chr17_41657127_41657278ETV42140.927968-0.924.9e-04Click!
chr17_41668721_41668956ETV4118500.164874-0.891.4e-03Click!
chr17_41614167_41614318ETV464400.145288-0.872.3e-03Click!
chr17_41665619_41665770ETV487060.170606-0.844.9e-03Click!
chr17_41669061_41669212ETV4121480.164406-0.835.3e-03Click!

Activity of the ETV4_ETS2 motif across conditions

Conditions sorted by the z-value of the ETV4_ETS2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_66344432_66344613 0.80 ARSG
arylsulfatase G
56863
0.1
chr20_47426342_47426648 0.79 PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
17925
0.25
chr9_95857166_95857358 0.55 RP11-274J16.5

549
0.64
chr1_198648783_198649296 0.52 RP11-553K8.5

12849
0.25
chr2_1159179_1159342 0.52 AC114808.2

3150
0.36
chr14_22698792_22699002 0.51 ENSG00000238634
.
88010
0.08
chr1_27945115_27945319 0.49 FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
5356
0.15
chr10_1748865_1749168 0.48 ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
30654
0.25
chr17_3876410_3876657 0.48 ATP2A3
ATPase, Ca++ transporting, ubiquitous
8797
0.19
chr3_13462527_13462772 0.47 NUP210
nucleoporin 210kDa
840
0.69
chr3_121992342_121992690 0.46 ENSG00000221474
.
8184
0.17
chr7_50359099_50359391 0.45 IKZF1
IKAROS family zinc finger 1 (Ikaros)
8000
0.29
chr11_1777117_1777382 0.44 CTSD
cathepsin D
1073
0.3
chr2_233637307_233637592 0.44 KCNJ13
potassium inwardly-rectifying channel, subfamily J, member 13
1334
0.35
chr14_106586968_106587173 0.44 IGHV3-13
immunoglobulin heavy variable 3-13
403
0.55
chr1_231747913_231748254 0.44 LINC00582
long intergenic non-protein coding RNA 582
247
0.93
chr10_75624787_75625518 0.43 CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
4540
0.13
chr1_79111221_79111724 0.43 IFI44
interferon-induced protein 44
4044
0.25
chr15_75761353_75761612 0.43 SIN3A
SIN3 transcription regulator family member A
13299
0.17
chr19_42380978_42381662 0.43 CD79A
CD79a molecule, immunoglobulin-associated alpha
30
0.96
chr5_131766860_131767115 0.41 AC116366.5

4581
0.15
chr9_7977098_7977328 0.41 TMEM261
transmembrane protein 261
177146
0.04
chr10_126300419_126300570 0.41 FAM53B-AS1
FAM53B antisense RNA 1
91700
0.07
chr20_37874398_37874627 0.41 ENSG00000211534
.
25671
0.24
chr1_245215119_245215800 0.41 ENSG00000251754
.
8229
0.17
chr4_109022130_109022312 0.41 LEF1
lymphoid enhancer-binding factor 1
65236
0.11
chr11_22679018_22679311 0.40 GAS2
growth arrest-specific 2
8997
0.19
chr5_169755785_169756172 0.40 KCNIP1
Kv channel interacting protein 1
24513
0.17
chr1_65329902_65330534 0.40 RAVER2
ribonucleoprotein, PTB-binding 2
86471
0.09
chr8_125207320_125207810 0.40 FER1L6-AS2
FER1L6 antisense RNA 2
23802
0.22
chr2_231526275_231526495 0.40 CAB39
calcium binding protein 39
51175
0.12
chr17_34617095_34617334 0.40 CCL3L1
chemokine (C-C motif) ligand 3-like 1
8505
0.15
chr9_117129895_117130125 0.39 AKNA
AT-hook transcription factor
9234
0.2
chr9_95845314_95845570 0.38 SUSD3
sushi domain containing 3
5314
0.17
chr3_187767704_187767957 0.38 LPP
LIM domain containing preferred translocation partner in lipoma
103242
0.07
chr3_15332186_15332608 0.38 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
14845
0.14
chr16_17542836_17543247 0.37 XYLT1
xylosyltransferase I
21697
0.29
chr2_43355341_43355494 0.37 ENSG00000207087
.
36785
0.2
chr2_127292142_127292584 0.37 GYPC
glycophorin C (Gerbich blood group)
121146
0.06
chr2_136887722_136888188 0.37 CXCR4
chemokine (C-X-C motif) receptor 4
12220
0.28
chr1_167596920_167597366 0.37 RCSD1
RCSD domain containing 1
2187
0.29
chr15_92638658_92638888 0.37 RP11-24J19.1

76893
0.12
chr9_92039484_92039635 0.37 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
5811
0.27
chr12_94517688_94517977 0.37 PLXNC1
plexin C1
24667
0.2
chr2_43360484_43360742 0.36 ENSG00000207087
.
41981
0.18
chr11_10466387_10466752 0.36 AMPD3
adenosine monophosphate deaminase 3
5299
0.22
chr11_6251311_6251645 0.36 FAM160A2
family with sequence similarity 160, member A2
4368
0.13
chr2_112456540_112456691 0.36 ENSG00000266063
.
72096
0.12
chr6_166747055_166747348 0.36 SFT2D1
SFT2 domain containing 1
8878
0.19
chr6_26478196_26478347 0.35 BTN2A1
butyrophilin, subfamily 2, member A1
12816
0.12
chr19_41808478_41808629 0.35 CCDC97
coiled-coil domain containing 97
7541
0.11
chr8_27226673_27226824 0.35 PTK2B
protein tyrosine kinase 2 beta
11420
0.22
chr7_36325933_36326467 0.35 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
10553
0.18
chr20_56200862_56201087 0.35 ZBP1
Z-DNA binding protein 1
5342
0.25
chr2_231361090_231361274 0.35 SP100
SP100 nuclear antigen
7795
0.21
chr1_226840930_226841348 0.35 ITPKB-IT1
ITPKB intronic transcript 1 (non-protein coding)
6232
0.23
chr22_50319499_50319650 0.34 CRELD2
cysteine-rich with EGF-like domains 2
7193
0.17
chr5_176722952_176723252 0.34 RAB24
RAB24, member RAS oncogene family
7605
0.12
chr2_69062364_69062558 0.34 AC097495.2

325
0.9
chr7_127751189_127751374 0.34 ENSG00000207588
.
29368
0.19
chr7_156689439_156689590 0.34 LMBR1
limb development membrane protein 1
3590
0.25
chr20_57757764_57758007 0.34 ZNF831
zinc finger protein 831
8190
0.26
chr2_99079929_99080200 0.33 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
18651
0.22
chr10_30783492_30783645 0.33 MAP3K8
mitogen-activated protein kinase kinase kinase 8
55817
0.12
chr14_52334181_52334332 0.33 GNG2
guanine nucleotide binding protein (G protein), gamma 2
6214
0.22
chr10_126393776_126393927 0.33 FAM53B-AS1
FAM53B antisense RNA 1
1098
0.53
chr2_106392462_106392714 0.33 NCK2
NCK adaptor protein 2
30400
0.23
chr14_35809472_35809661 0.33 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
29527
0.18
chr12_9918241_9918423 0.33 CD69
CD69 molecule
4835
0.18
chr3_123242131_123242282 0.33 PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
22666
0.2
chr14_106453805_106454306 0.32 IGHV1-2
immunoglobulin heavy variable 1-2
885
0.24
chr3_186588899_186589622 0.32 ADIPOQ-AS1
ADIPOQ antisense RNA 1
15348
0.12
chr3_12654461_12654707 0.32 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
1080
0.49
chr1_247570539_247571127 0.32 NLRP3
NLR family, pyrin domain containing 3
8625
0.18
chr14_55321009_55321209 0.32 ENSG00000252019
.
4824
0.23
chr9_14994733_14994933 0.32 RP11-54D18.3

53226
0.15
chr1_233114549_233114766 0.31 NTPCR
nucleoside-triphosphatase, cancer-related
28271
0.23
chr11_45002209_45002427 0.31 TP53I11
tumor protein p53 inducible protein 11
29710
0.22
chr21_36080496_36080697 0.31 AP000330.8

37458
0.17
chr11_117922812_117923152 0.31 ENSG00000272075
.
14970
0.15
chr8_52912939_52913092 0.31 RP11-110G21.1

100721
0.07
chr19_15625593_15626001 0.31 CYP4F22
cytochrome P450, family 4, subfamily F, polypeptide 22
6493
0.15
chr14_51278970_51279194 0.31 RP11-286O18.1

9516
0.15
chr19_33648919_33649221 0.31 ENSG00000264355
.
18908
0.12
chr10_73514684_73515259 0.31 C10orf54
chromosome 10 open reading frame 54
2416
0.29
chr19_10982774_10983002 0.31 CARM1
coactivator-associated arginine methyltransferase 1
509
0.7
chr7_140058363_140058567 0.31 SLC37A3
solute carrier family 37, member 3
6565
0.15
chr1_209921995_209922325 0.31 TRAF3IP3
TRAF3 interacting protein 3
7217
0.14
chr1_229193442_229194258 0.31 RP5-1061H20.5

169459
0.03
chr10_51504373_51504582 0.30 AGAP7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
18150
0.18
chr4_13616920_13617103 0.30 BOD1L1
biorientation of chromosomes in cell division 1-like 1
12336
0.19
chr14_101718457_101718677 0.30 ENSG00000206761
.
106535
0.03
chr21_34616709_34617146 0.30 AP000295.9

2152
0.24
chr8_81288726_81288959 0.30 ENSG00000252884
.
28909
0.19
chr19_7783538_7783845 0.30 CLEC4G
C-type lectin domain family 4, member G
13366
0.09
chr8_126275118_126275439 0.30 ENSG00000242170
.
7568
0.27
chr10_80825552_80825775 0.30 ZMIZ1-AS1
ZMIZ1 antisense RNA 1
1562
0.44
chr1_156084846_156085321 0.30 LMNA
lamin A/C
570
0.62
chrX_147391899_147392419 0.30 AC002368.4

189976
0.03
chrX_19369143_19369294 0.30 PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
4482
0.28
chr1_114422656_114422813 0.30 BCL2L15
BCL2-like 15
7263
0.12
chr1_226900136_226900391 0.30 ITPKB
inositol-trisphosphate 3-kinase B
24896
0.18
chr7_142503625_142503977 0.30 PRSS3P2
protease, serine, 3 pseudogene 2
22670
0.15
chr9_130541716_130542127 0.30 SH2D3C
SH2 domain containing 3C
901
0.36
chr1_212968214_212968462 0.30 TATDN3
TatD DNase domain containing 3
313
0.88
chr8_41890196_41890347 0.29 ENSG00000238966
.
10822
0.2
chr1_26616271_26616515 0.29 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
9780
0.11
chr12_94598358_94598823 0.29 RP11-74K11.2

18770
0.19
chr10_22780969_22781267 0.29 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
99486
0.07
chr16_68108782_68108933 0.29 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
10390
0.1
chr12_94638571_94638798 0.29 PLXNC1
plexin C1
9610
0.18
chr17_55508669_55509100 0.29 ENSG00000263902
.
19322
0.24
chr11_73725373_73725524 0.29 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
4968
0.18
chr11_201596_201747 0.29 RP11-304M2.5

1952
0.16
chr7_150329408_150329559 0.29 GIMAP6
GTPase, IMAP family member 6
10
0.98
chr14_31679580_31679731 0.29 HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
2645
0.24
chr17_2697596_2697803 0.29 RAP1GAP2
RAP1 GTPase activating protein 2
2033
0.3
chrX_65225518_65225769 0.29 RP6-159A1.3

6050
0.22
chr5_176723283_176724082 0.29 RAB24
RAB24, member RAS oncogene family
7025
0.12
chr19_14549826_14550082 0.29 PKN1
protein kinase N1
1118
0.36
chr13_46752398_46752790 0.29 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
3865
0.19
chr11_60931918_60932069 0.29 VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
2904
0.22
chr1_28582798_28582949 0.29 SESN2
sestrin 2
3165
0.16
chr2_131723685_131723880 0.29 ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
35251
0.15
chr1_231750383_231750879 0.29 LINC00582
long intergenic non-protein coding RNA 582
2795
0.27
chr11_6693256_6693542 0.29 MRPL17
mitochondrial ribosomal protein L17
11148
0.1
chr2_87874778_87875151 0.29 ENSG00000265507
.
54310
0.16
chr16_23908409_23908633 0.29 PRKCB
protein kinase C, beta
59977
0.13
chr1_181059966_181060133 0.28 IER5
immediate early response 5
2411
0.34
chr15_52053125_52053320 0.28 CTD-2308G16.1

8540
0.14
chr5_527247_527623 0.28 RP11-310P5.2

2615
0.18
chr2_233083878_233084231 0.28 ENSG00000207626
.
46691
0.14
chr7_6065786_6066227 0.28 EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
177
0.89
chr2_202074008_202074192 0.28 CASP8
caspase 8, apoptosis-related cysteine peptidase
24066
0.14
chr4_184949026_184949285 0.28 STOX2
storkhead box 2
26677
0.21
chr3_188838639_188838790 0.28 TPRG1
tumor protein p63 regulated 1
20804
0.28
chr6_83073756_83074156 0.28 TPBG
trophoblast glycoprotein
5
0.99
chr10_126365162_126365313 0.28 FAM53B-AS1
FAM53B antisense RNA 1
26957
0.19
chr21_46334235_46334386 0.28 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
112
0.94
chr10_78801343_78801560 0.28 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
37831
0.2
chr20_58586927_58587156 0.28 CDH26
cadherin 26
15592
0.2
chrX_70379151_70379501 0.28 NLGN3
neuroligin 3
14614
0.11
chr16_17469640_17470020 0.27 XYLT1
xylosyltransferase I
94908
0.1
chr22_25784908_25785204 0.27 LRP5L
low density lipoprotein receptor-related protein 5-like
7512
0.22
chr21_15922138_15922469 0.27 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
3639
0.29
chr2_136884931_136885082 0.27 CXCR4
chemokine (C-X-C motif) receptor 4
9271
0.29
chr14_104858355_104858716 0.27 ENSG00000222761
.
8850
0.27
chr9_78781333_78781701 0.27 PCSK5
proprotein convertase subtilisin/kexin type 5
22038
0.28
chr4_56263060_56263211 0.27 TMEM165
transmembrane protein 165
1005
0.37
chr9_35618104_35618377 0.27 CD72
CD72 molecule
127
0.91
chr5_138414055_138414601 0.27 SIL1
SIL1 nucleotide exchange factor
35957
0.15
chr6_42358231_42358398 0.27 ENSG00000221252
.
21820
0.2
chr2_99271555_99271876 0.27 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
8221
0.22
chr3_177661794_177662251 0.27 ENSG00000199858
.
63545
0.15
chr6_70526539_70526715 0.27 LMBRD1
LMBR1 domain containing 1
19624
0.25
chr7_1089147_1089438 0.27 GPR146
G protein-coupled receptor 146
5080
0.11
chr7_149561438_149561589 0.27 RP4-751H13.7

1932
0.29
chr16_75139857_75140251 0.27 ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
1372
0.36
chr16_30949063_30949295 0.27 FBXL19
F-box and leucine-rich repeat protein 19
4517
0.09
chr6_37939838_37940078 0.27 ZFAND3
zinc finger, AN1-type domain 3
42223
0.17
chr9_92096327_92096478 0.27 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
1597
0.45
chr12_109714684_109714945 0.27 FOXN4
forkhead box N4
9714
0.21
chr16_21627363_21627564 0.27 METTL9
methyltransferase like 9
1756
0.25
chr4_3198531_3198813 0.27 HTT
huntingtin
36583
0.16
chr7_29284217_29284368 0.27 AC004593.3

35706
0.16
chr9_92077290_92077553 0.27 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
6553
0.25
chr1_33448728_33449007 0.27 RP1-117O3.2

3809
0.17
chr10_97518313_97518724 0.27 ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
2804
0.31
chr22_29204880_29205031 0.27 CTA-292E10.8

5947
0.15
chr20_35272363_35272546 0.27 SLA2
Src-like-adaptor 2
1830
0.26
chr18_46407234_46407394 0.27 RP11-484L8.1

46173
0.16
chr11_73721865_73722409 0.27 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
1657
0.32
chr2_8612472_8612957 0.26 AC011747.7

203182
0.03
chr15_51368814_51368965 0.26 RP11-394B5.2

7106
0.24
chr12_7499136_7499301 0.26 CD163L1
CD163 molecule-like 1
22348
0.18
chr6_42000091_42000640 0.26 ENSG00000206875
.
14113
0.15
chr21_48025165_48025458 0.26 S100B
S100 calcium binding protein B
190
0.95
chr10_73845525_73845681 0.26 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
2483
0.34
chr1_40309344_40309495 0.26 ENSG00000202222
.
37931
0.09
chr9_134454368_134454603 0.26 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
42740
0.12
chr6_42343431_42343582 0.26 ENSG00000221252
.
36628
0.17
chr3_195826753_195826904 0.26 TFRC
transferrin receptor
17768
0.16
chr10_3709087_3709289 0.26 RP11-184A2.3

84071
0.1
chr7_149562206_149562836 0.26 RP4-751H13.7

2940
0.22
chr8_125210409_125210588 0.26 FER1L6-AS2
FER1L6 antisense RNA 2
26735
0.21
chr19_6766080_6766650 0.26 SH2D3A
SH2 domain containing 3A
1081
0.38
chr15_50554636_50555120 0.26 HDC
histidine decarboxylase
748
0.6
chr4_169427075_169427226 0.26 PALLD
palladin, cytoskeletal associated protein
5569
0.22
chr1_246187527_246187678 0.26 RP11-83A16.1

9251
0.28
chr7_101784523_101784872 0.26 ENSG00000252824
.
52747
0.12
chr11_69009932_69010222 0.26 MYEOV
myeloma overexpressed
51528
0.15
chr1_211483375_211483526 0.26 TRAF5
TNF receptor-associated factor 5
16507
0.21
chr19_55219671_55220067 0.26 ENSG00000266427
.
1861
0.19
chr9_137287207_137287358 0.26 RXRA
retinoid X receptor, alpha
11146
0.23
chr8_54794402_54794553 0.25 RGS20
regulator of G-protein signaling 20
1023
0.52
chr2_8451327_8451593 0.25 AC011747.7

364436
0.01
chr3_16884759_16884923 0.25 PLCL2
phospholipase C-like 2
41611
0.19
chr18_43580594_43580948 0.25 ENSG00000222179
.
10860
0.19
chr11_117841509_117841660 0.25 IL10RA
interleukin 10 receptor, alpha
15479
0.17
chr16_3121743_3122141 0.25 ENSG00000252561
.
2418
0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV4_ETS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.4 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.4 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.1 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.3 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0002645 regulation of tolerance induction(GO:0002643) positive regulation of tolerance induction(GO:0002645)
0.0 0.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.5 GO:0000303 response to superoxide(GO:0000303)
0.0 0.2 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 0.4 GO:0036230 granulocyte activation(GO:0036230)
0.0 0.3 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0043367 CD4-positive, alpha-beta T cell activation(GO:0035710) CD4-positive, alpha-beta T cell differentiation(GO:0043367)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:1903319 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0051132 NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0010939 regulation of necrotic cell death(GO:0010939)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.2 GO:0002920 regulation of humoral immune response(GO:0002920)
0.0 0.1 GO:0002724 T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0098543 detection of other organism(GO:0098543)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0 0.5 GO:0016236 macroautophagy(GO:0016236)
0.0 0.0 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.2 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0006266 DNA ligation(GO:0006266)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0052803 histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0051709 regulation of killing of cells of other organism(GO:0051709)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0072193 positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.0 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.0 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0031342 negative regulation of cell killing(GO:0031342)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0010535 regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0 0.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0045069 regulation of viral genome replication(GO:0045069)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.2 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.0 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC