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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ETV6

Z-value: 1.73

Motif logo

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Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ETV6
ENSG00000139083.6 ETV6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ETV6chr12_11993430_11993581453660.1899770.901.0e-03Click!
ETV6chr12_11954306_11954457489460.1784140.881.9e-03Click!
ETV6chr12_11971660_11971811663000.1339820.835.3e-03Click!
ETV6chr12_11819592_11819743168790.2565240.835.9e-03Click!
ETV6chr12_11819415_11819566167020.2569240.826.3e-03Click!

Activity of the ETV6 motif across conditions

Conditions sorted by the z-value of the ETV6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_134162105_134162300 0.69 TG
 thyroglobulin
 36455
 0.15
chr16_53127962_53128318 0.52 CHD9
 chromodomain helicase DNA binding protein 9
 4932
 0.27
chr4_185269211_185269362 0.52 ENSG00000244512
 .
 69197
 0.09
chr11_72498251_72498402 0.50 STARD10
 StAR-related lipid transfer (START) domain containing 10
 1314
 0.31
chr11_59495823_59496091 0.50 OR10V1
 olfactory receptor, family 10, subfamily V, member 1
 14620
 0.12
chr21_40382908_40383154 0.49 ENSG00000272015
 .
 116322
 0.06
chr19_6887176_6887376 0.49 EMR1
 egf-like module containing, mucin-like, hormone receptor-like 1
 301
 0.88
chr6_44201103_44201369 0.48 SLC29A1
 solute carrier family 29 (equilibrative nucleoside transporter), member 1
 6360
 0.12
chr5_39228625_39228776 0.47 FYB
 FYN binding protein
 8992
 0.29
chr1_21863061_21863212 0.47 ALPL
 alkaline phosphatase, liver/bone/kidney
 14636
 0.19
chr8_130696046_130696267 0.46 GSDMC
 gasdermin C
 102978
 0.06
chr3_194456653_194456804 0.46 FAM43A
 family with sequence similarity 43, member A
 50106
 0.11
chr6_145099214_145099365 0.46 UTRN
 utrophin
 11076
 0.33
chr2_99872403_99872554 0.45 LYG2
 lysozyme G-like 2
 733
 0.65
chr14_89950953_89951233 0.45 FOXN3
 forkhead box N3
 9302
 0.21
chr21_34439817_34440107 0.44 OLIG1
 oligodendrocyte transcription factor 1
 2488
 0.25
chr1_47052866_47053017 0.44 MKNK1
 MAP kinase interacting serine/threonine kinase 1
 1010
 0.47
chr4_86618813_86618964 0.44 ENSG00000266421
 .
 24733
 0.25
chr3_60833462_60833730 0.44 ENSG00000212211
 .
 8681
 0.34
chr13_49790716_49790984 0.43 MLNR
 motilin receptor
 3624
 0.28
chr3_14459825_14460205 0.42 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 14163
 0.22
chr13_32621986_32622137 0.42 FRY
 furry homolog (Drosophila)
 12940
 0.22
chr5_173145182_173145333 0.41 ENSG00000263401
 .
 11824
 0.27
chr7_115980158_115980451 0.41 ENSG00000216076
 .
 5694
 0.22
chr8_37761152_37761429 0.41 RAB11FIP1
 RAB11 family interacting protein 1 (class I)
 4305
 0.16
chr21_37558737_37558888 0.41 DOPEY2
 dopey family member 2
 21979
 0.12
chr1_167127932_167128119 0.41 RP11-277B15.2
36692
 0.13
chr2_10538806_10538994 0.40 HPCAL1
 hippocalcin-like 1
 21247
 0.18
chr11_59823736_59824267 0.40 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
 59
 0.97
chr14_21025165_21025316 0.40 RNASE9
 ribonuclease, RNase A family, 9 (non-active)
 3850
 0.14
chr3_39323163_39323419 0.40 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 65
 0.98
chr6_6724343_6724679 0.39 LY86-AS1
 LY86 antisense RNA 1
 101507
 0.08
chr17_1674840_1675255 0.39 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 34
 0.96
chr11_78062676_78062877 0.39 GAB2
 GRB2-associated binding protein 2
 9850
 0.18
chr4_40623166_40623743 0.39 RBM47
 RNA binding motif protein 47
 8427
 0.27
chr9_93567526_93567713 0.38 SYK
 spleen tyrosine kinase
 3410
 0.4
chr6_12963445_12963682 0.38 PHACTR1
 phosphatase and actin regulator 1
 5349
 0.34
chr5_175101372_175101562 0.37 HRH2
 histamine receptor H2
 6997
 0.22
chr4_26220381_26220779 0.37 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 53649
 0.18
chr15_69990444_69990636 0.37 ENSG00000238870
 .
 32621
 0.21
chr3_72572531_72572682 0.37 ENSG00000238568
 .
 49510
 0.14
chr20_39123475_39123626 0.36 ENSG00000252434
 .
 78035
 0.12
chr8_48309430_48309581 0.36 SPIDR
 scaffolding protein involved in DNA repair
 43458
 0.19
chr1_25304935_25305322 0.36 RUNX3
 runt-related transcription factor 3
 13627
 0.19
chr10_73396625_73396776 0.36 CDH23
 cadherin-related 23
 8973
 0.26
chr18_77403247_77403434 0.36 CTDP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
 36461
 0.19
chr20_44538606_44538964 0.36 PLTP
 phospholipid transfer protein
 791
 0.42
chr17_27346283_27346434 0.36 AC024619.2
3998
 0.13
chr8_141123630_141123910 0.36 C8orf17
 chromosome 8 open reading frame 17
 180354
 0.03
chr19_2188091_2188301 0.35 DOT1L
 DOT1-like histone H3K79 methyltransferase
 24012
 0.08
chr1_42195372_42195655 0.35 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 28841
 0.2
chr19_6672050_6672201 0.35 TNFSF14
 tumor necrosis factor (ligand) superfamily, member 14
 1526
 0.31
chr8_8966758_8966909 0.35 RP11-10A14.3
32101
 0.12
chr10_26626064_26626215 0.35 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
 100993
 0.08
chr18_77269072_77269296 0.34 AC018445.1
 Uncharacterized protein
 6873
 0.29
chr2_113597888_113598039 0.34 IL1B
 interleukin 1, beta
 3483
 0.2
chr13_32685646_32685859 0.34 FRY
 furry homolog (Drosophila)
 50751
 0.16
chr1_161211637_161212023 0.33 NR1I3
 nuclear receptor subfamily 1, group I, member 3
 3738
 0.09
chrX_108977400_108977585 0.33 ACSL4
 acyl-CoA synthetase long-chain family member 4
 860
 0.67
chrX_25067386_25067645 0.33 ENSG00000240439
 .
 11541
 0.25
chr1_32123678_32123829 0.33 RP11-73M7.6
894
 0.46
chr3_184095207_184095533 0.33 THPO
 thrombopoietin
 558
 0.59
chr12_10204798_10205132 0.33 CLEC9A
 C-type lectin domain family 9, member A
 21689
 0.1
chr15_70005461_70005680 0.33 ENSG00000238870
 .
 17591
 0.25
chr15_67158530_67158864 0.33 SMAD6
 SMAD family member 6
 154662
 0.04
chr20_1878767_1878918 0.33 SIRPA
 signal-regulatory protein alpha
 2900
 0.32
chr4_8270805_8271133 0.33 HTRA3
 HtrA serine peptidase 3
 523
 0.82
chr1_36952288_36952439 0.33 CSF3R
 colony stimulating factor 3 receptor (granulocyte)
 3484
 0.21
chr6_37984799_37985021 0.33 ZFAND3
 zinc finger, AN1-type domain 3
 87175
 0.09
chr2_26549164_26549440 0.33 GPR113
 G protein-coupled receptor 113
 7332
 0.2
chr6_146917295_146917531 0.33 ADGB
 androglobin
 2688
 0.34
chr1_33514881_33515110 0.33 AK2
 adenylate kinase 2
 12402
 0.17
chr10_48483820_48483971 0.33 GDF10
 growth differentiation factor 10
 44919
 0.14
chr19_49920997_49921157 0.32 PTH2
 parathyroid hormone 2
 5621
 0.07
chr14_70111444_70111741 0.32 KIAA0247
 KIAA0247
 33279
 0.18
chr4_2806746_2806916 0.32 SH3BP2
 SH3-domain binding protein 2
 6106
 0.21
chr7_2832108_2832259 0.32 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 22709
 0.22
chr11_3845898_3846068 0.32 RHOG
 ras homolog family member G
 5898
 0.1
chr19_52074425_52074576 0.32 ZNF175
 zinc finger protein 175
 51
 0.96
chr14_65509694_65510092 0.32 ENSG00000266531
 .
 1513
 0.32
chr1_22454794_22454972 0.32 WNT4
 wingless-type MMTV integration site family, member 4
 1461
 0.43
chr3_47338789_47338970 0.32 KIF9
 kinesin family member 9
 13938
 0.16
chr2_57827496_57827758 0.32 ENSG00000212168
 .
 55957
 0.18
chr8_61798114_61798398 0.32 RP11-33I11.2
76091
 0.12
chrX_123517274_123517517 0.32 SH2D1A
 SH2 domain containing 1A
 36956
 0.23
chr10_94547379_94547538 0.32 EXOC6
 exocyst complex component 6
 43477
 0.16
chr2_43460695_43460846 0.32 AC010883.5
4058
 0.27
chr3_17076946_17077097 0.31 PLCL2-AS1
 PLCL2 antisense RNA 1
 8663
 0.24
chr7_74498503_74498654 0.31 WBSCR16
 Williams-Beuren syndrome chromosome region 16
 8514
 0.22
chr20_1800907_1801169 0.31 SIRPA
 signal-regulatory protein alpha
 74116
 0.1
chr5_135347652_135347946 0.31 TGFBI
 transforming growth factor, beta-induced, 68kDa
 16785
 0.2
chr12_56371376_56371555 0.31 RAB5B
 RAB5B, member RAS oncogene family
 3580
 0.1
chr17_56361536_56361794 0.31 MPO
 myeloperoxidase
 3369
 0.16
chr19_14898095_14898371 0.31 EMR2
 egf-like module containing, mucin-like, hormone receptor-like 2
 8880
 0.14
chr4_185924099_185924250 0.31 HELT
 helt bHLH transcription factor
 15821
 0.22
chr16_66577982_66578230 0.31 TK2
 thymidine kinase 2, mitochondrial
 5595
 0.1
chr18_24356811_24356962 0.31 AQP4
 aquaporin 4
 85926
 0.08
chr8_29242547_29242792 0.31 RP4-676L2.1
31982
 0.15
chr7_141875353_141875504 0.31 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
 63874
 0.1
chr20_58713423_58713574 0.31 C20orf197
 chromosome 20 open reading frame 197
 82518
 0.1
chr8_61851808_61852029 0.31 CLVS1
 clavesin 1
 117799
 0.06
chr17_74099339_74099490 0.31 EXOC7
 exocyst complex component 7
 63
 0.95
chr4_152774376_152774527 0.30 PET112
 PET112 homolog (yeast)
 92276
 0.08
chr2_65296545_65296800 0.30 CEP68
 centrosomal protein 68kDa
 13073
 0.17
chr14_75714237_75714434 0.30 RP11-293M10.2
11779
 0.15
chr2_109872100_109872486 0.30 ENSG00000265965
 .
 57788
 0.15
chr19_33771380_33771704 0.30 CTD-2540B15.11
19298
 0.12
chr6_139090481_139090632 0.30 CCDC28A
 coiled-coil domain containing 28A
 4101
 0.24
chr15_77713368_77713519 0.30 HMG20A
 high mobility group 20A
 90
 0.95
chr3_113326958_113327109 0.30 ENSG00000265253
 .
 13310
 0.15
chr16_58889405_58889622 0.30 ENSG00000244003
 .
 85085
 0.09
chr16_84377709_84377860 0.30 ATP2C2
 ATPase, Ca++ transporting, type 2C, member 2
 24349
 0.15
chr5_139594871_139595091 0.29 CTB-131B5.2
15233
 0.14
chr10_126696899_126697050 0.29 CTBP2
 C-terminal binding protein 2
 2392
 0.3
chr15_31700478_31700629 0.29 KLF13
 Kruppel-like factor 13
 42196
 0.21
chr22_42832185_42832336 0.29 NFAM1
 NFAT activating protein with ITAM motif 1
 3859
 0.23
chr12_78393170_78393321 0.29 NAV3
 neuron navigator 3
 33189
 0.24
chr1_146675856_146676007 0.29 FMO5
 flavin containing monooxygenase 5
 20970
 0.14
chr2_64610358_64610618 0.29 ENSG00000264297
 .
 42595
 0.16
chr5_81133416_81133809 0.29 SSBP2
 single-stranded DNA binding protein 2
 86540
 0.09
chr11_22829816_22830016 0.29 RP11-17A1.3
21010
 0.18
chr7_157129016_157129203 0.29 DNAJB6
 DnaJ (Hsp40) homolog, subfamily B, member 6
 551
 0.82
chr15_78691765_78692045 0.29 IREB2
 iron-responsive element binding protein 2
 37868
 0.12
chr1_212768754_212768905 0.29 ATF3
 activating transcription factor 3
 13183
 0.15
chr4_37948267_37948441 0.29 PTTG2
 pituitary tumor-transforming 2
 13702
 0.24
chr1_183544894_183545045 0.29 NCF2
 neutrophil cytosolic factor 2
 6609
 0.21
chr3_128532158_128532319 0.29 RAB7A
 RAB7A, member RAS oncogene family
 18036
 0.16
chr17_8324143_8324299 0.29 NDEL1
 nudE neurodevelopment protein 1-like 1
 7772
 0.12
chr21_43431068_43431344 0.29 ZBTB21
 zinc finger and BTB domain containing 21
 710
 0.7
chr1_152492276_152492444 0.28 CRCT1
 cysteine-rich C-terminal 1
 5382
 0.15
chr3_138620560_138620746 0.28 FOXL2
 forkhead box L2
 45329
 0.13
chr11_65584293_65584444 0.28 SNX32
 sorting nexin 32
 16744
 0.08
chr4_8349838_8350141 0.28 ENSG00000202054
 .
 44753
 0.14
chr13_29148843_29149031 0.28 FLT1
 fms-related tyrosine kinase 1
 79672
 0.1
chr4_86590486_86590637 0.28 ENSG00000266421
 .
 53060
 0.16
chrX_119150159_119150382 0.28 RP4-755D9.1
19931
 0.17
chr2_119130151_119130302 0.28 INSIG2
 insulin induced gene 2
 284176
 0.01
chr13_60576787_60576938 0.28 DIAPH3-AS1
 DIAPH3 antisense RNA 1
 10023
 0.25
chr9_124299702_124300078 0.28 ENSG00000252940
 .
 2265
 0.29
chr19_19143693_19143980 0.28 SUGP2
 SURP and G patch domain containing 2
 407
 0.54
chr10_134198535_134198861 0.28 PWWP2B
 PWWP domain containing 2B
 11974
 0.18
chr15_69606302_69606478 0.28 PAQR5
 progestin and adipoQ receptor family member V
 352
 0.82
chr8_10669979_10670130 0.28 PINX1
 PIN2/TERF1 interacting, telomerase inhibitor 1
 27227
 0.12
chr3_151107193_151107344 0.28 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
 4668
 0.23
chr11_61683909_61684462 0.28 RAB3IL1
 RAB3A interacting protein (rabin3)-like 1
 812
 0.51
chr1_175097367_175097518 0.27 TNN
 tenascin N
 60448
 0.11
chr12_27153812_27154240 0.27 TM7SF3
 transmembrane 7 superfamily member 3
 2192
 0.25
chr12_32629297_32629583 0.27 ENSG00000253063
 .
 965
 0.61
chr9_132316854_132317005 0.27 RP11-492E3.2
20759
 0.14
chr11_113968901_113969117 0.27 ENSG00000221112
 .
 11358
 0.23
chr22_30648620_30649241 0.27 LIF
 leukemia inhibitory factor
 6090
 0.11
chr11_43855946_43856097 0.27 RP11-613D13.5
529
 0.81
chr14_59827605_59828209 0.27 ENSG00000252869
 .
 38834
 0.18
chr15_65139770_65140076 0.27 AC069368.3
 Uncharacterized protein
 5776
 0.14
chr6_15428120_15428372 0.27 JARID2
 jumonji, AT rich interactive domain 2
 27157
 0.23
chr16_84766620_84766890 0.27 USP10
 ubiquitin specific peptidase 10
 33109
 0.16
chr6_116889940_116890146 0.27 RWDD1
 RWD domain containing 1
 2487
 0.21
chr14_107081781_107081932 0.27 IGHV4-59
 immunoglobulin heavy variable 4-59
 1869
 0.07
chr10_105785288_105785439 0.27 COL17A1
 collagen, type XVII, alpha 1
 7363
 0.18
chr16_31141073_31141404 0.27 RP11-388M20.2
1516
 0.15
chr1_109742432_109742583 0.27 ENSG00000238310
 .
 7963
 0.15
chr2_73207068_73207254 0.27 EMX1
 empty spiracles homeobox 1
 56044
 0.12
chr16_81498895_81499086 0.27 CMIP
 c-Maf inducing protein
 20215
 0.24
chr6_126307498_126307649 0.27 TRMT11
 tRNA methyltransferase 11 homolog (S. cerevisiae)
 3
 0.98
chr1_208017036_208017239 0.27 ENSG00000203709
 .
 41269
 0.16
chr7_47846848_47846999 0.27 PKD1L1
 polycystic kidney disease 1 like 1
 5912
 0.22
chr8_116470203_116470515 0.27 TRPS1
 trichorhinophalangeal syndrome I
 34089
 0.22
chr2_24292097_24292248 0.27 SF3B14
 Pre-mRNA branch site protein p14
 7141
 0.11
chr2_86102638_86102927 0.26 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 8005
 0.21
chr9_125059861_125060215 0.26 ENSG00000264227
 .
 1604
 0.3
chr20_33872479_33872715 0.26 EIF6
 eukaryotic translation initiation factor 6
 24
 0.87
chr2_149303357_149303735 0.26 MBD5
 methyl-CpG binding domain protein 5
 77252
 0.11
chr19_42051966_42052728 0.26 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
 3539
 0.21
chr7_100400756_100400965 0.26 ENSG00000263672
 .
 18026
 0.1
chr7_138720207_138720441 0.26 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
 451
 0.85
chr14_60619421_60619786 0.26 DHRS7
 dehydrogenase/reductase (SDR family) member 7
 289
 0.92
chr17_44983331_44983711 0.26 ENSG00000210709
 .
 14969
 0.15
chr2_183989474_183989788 0.26 NUP35
 nucleoporin 35kDa
 458
 0.82
chr5_177667186_177667397 0.26 PHYKPL
 5-phosphohydroxy-L-lysine phospho-lyase
 7505
 0.21
chr8_67693713_67693929 0.26 SGK3
 serum/glucocorticoid regulated kinase family, member 3
 6020
 0.24
chr10_64612517_64612668 0.26 EGR2
 early growth response 2
 33665
 0.17
chr15_43562661_43562823 0.25 TGM5
 transglutaminase 5
 3687
 0.15
chr7_127693207_127693470 0.25 LRRC4
 leucine rich repeat containing 4
 21178
 0.2
chr16_58058882_58059051 0.25 MMP15
 matrix metallopeptidase 15 (membrane-inserted)
 504
 0.72
chr22_38023733_38023903 0.25 SH3BP1
 SH3-domain binding protein 1
 11664
 0.1
chr2_190424109_190424405 0.25 SLC40A1
 solute carrier family 40 (iron-regulated transporter), member 1
 21356
 0.22
chr10_51504373_51504582 0.25 AGAP7
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
 18150
 0.18
chr9_123433443_123433594 0.25 MEGF9
 multiple EGF-like-domains 9
 43094
 0.17
chr9_113092238_113092389 0.25 TXNDC8
 thioredoxin domain containing 8 (spermatozoa)
 7775
 0.23
chr12_54686387_54686538 0.25 NFE2
 nuclear factor, erythroid 2
 3080
 0.11
chr15_75761353_75761612 0.25 SIN3A
 SIN3 transcription regulator family member A
 13299
 0.17
chr7_38295749_38295900 0.25 STARD3NL
 STARD3 N-terminal like
 77827
 0.12
chr12_49360293_49360446 0.25 WNT10B
 wingless-type MMTV integration site family, member 10B
 4170
 0.08
chr4_142558013_142558295 0.25 IL15
 interleukin 15
 54
 0.99
chr2_216371790_216371973 0.24 AC012462.1
70905
 0.11
chr17_77755803_77755954 0.24 CBX2
 chromobox homolog 2
 3885
 0.16
chr5_55904489_55904655 0.24 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 2513
 0.36
chr11_128236040_128236191 0.24 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 139174
 0.05
chr18_2653058_2653283 0.24 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
 2567
 0.22
chr5_171839971_171840157 0.24 ENSG00000216127
 .
 26694
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ETV6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.4 GO:0009415 response to water(GO:0009415)
0.1 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.1 GO:2000319 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061) regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0090594 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0070849 response to epidermal growth factor(GO:0070849)
0.0 0.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:1990266 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0090494 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.0 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0043954 cellular component maintenance(GO:0043954)
0.0 0.0 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits