Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ETV7

Z-value: 1.16

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Transcription factors associated with ETV7

Gene Symbol Gene ID Gene Info
ENSG00000010030.9 ETS variant transcription factor 7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_36355012_36355199ETV73880.543896-0.333.9e-01Click!
chr6_36355753_36356314ETV71310.9334510.078.7e-01Click!
chr6_36355421_36355572ETV730.945827-0.001.0e+00Click!

Activity of the ETV7 motif across conditions

Conditions sorted by the z-value of the ETV7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_13697746_13698201 0.32 FAR1-IT1
FAR1 intronic transcript 1 (non-protein coding)
7099
0.2
chr14_51886452_51886750 0.30 FRMD6
FERM domain containing 6
69254
0.11
chr4_154581482_154581754 0.29 RP11-153M7.3

17793
0.19
chr9_137233668_137233871 0.23 RXRA
retinoid X receptor, alpha
15343
0.23
chr1_92846574_92846807 0.23 ENSG00000242764
.
21552
0.21
chr7_28723084_28723448 0.22 CREB5
cAMP responsive element binding protein 5
2332
0.46
chrX_13269027_13269605 0.22 GS1-600G8.3

59455
0.14
chr2_7144203_7144376 0.22 RNF144A
ring finger protein 144A
7218
0.26
chr17_32570710_32570941 0.22 CCL2
chemokine (C-C motif) ligand 2
11479
0.13
chr11_35873645_35873874 0.21 ENSG00000266590
.
8535
0.22
chr6_48850860_48851011 0.21 ENSG00000221175
.
33375
0.25
chr8_142136676_142136992 0.21 RP11-809O17.1

1386
0.38
chr2_113597075_113597265 0.21 IL1B
interleukin 1, beta
2690
0.24
chr10_5644211_5644362 0.21 ENSG00000240577
.
29140
0.14
chr16_57717963_57718157 0.21 CCDC135
coiled-coil domain containing 135
10645
0.12
chr10_60400963_60401249 0.20 BICC1
bicaudal C homolog 1 (Drosophila)
128206
0.06
chr5_150477041_150477197 0.20 TNIP1
TNFAIP3 interacting protein 1
3981
0.23
chr6_167142675_167142845 0.20 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
28639
0.23
chr9_224674_224929 0.20 C9orf66
chromosome 9 open reading frame 66
8908
0.18
chr8_20004646_20004840 0.20 SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
33732
0.16
chr17_29280275_29280468 0.20 AC091177.1

3608
0.12
chr5_177859454_177859724 0.20 CTB-26E19.1

10506
0.23
chr5_149837604_149837792 0.20 RPS14
ribosomal protein S14
8379
0.18
chr10_135093978_135094209 0.20 ADAM8
ADAM metallopeptidase domain 8
3721
0.12
chr4_185819623_185819887 0.19 ENSG00000263458
.
39839
0.14
chr2_100388072_100388250 0.19 AFF3
AF4/FMR2 family, member 3
193329
0.03
chr2_85777153_85777517 0.19 MAT2A
methionine adenosyltransferase II, alpha
10570
0.09
chr11_105052468_105053090 0.19 CARD18
caspase recruitment domain family, member 18
42326
0.16
chr2_60598504_60598911 0.19 ENSG00000200807
.
13033
0.23
chr2_118856015_118856215 0.19 INSIG2
insulin induced gene 2
10065
0.24
chr9_92275563_92275780 0.19 GADD45G
growth arrest and DNA-damage-inducible, gamma
55718
0.16
chr13_45376199_45376477 0.18 ENSG00000238932
.
173529
0.03
chr18_43381728_43382214 0.18 SIGLEC15
sialic acid binding Ig-like lectin 15
23506
0.18
chr2_166672118_166672418 0.18 ENSG00000221234
.
1543
0.44
chr11_43713235_43713438 0.18 HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
11005
0.26
chr3_151139810_151140059 0.18 IGSF10
immunoglobulin superfamily, member 10
21004
0.19
chr21_40107907_40108234 0.18 ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
69161
0.12
chr12_93521110_93521555 0.18 RP11-511B23.2

11535
0.21
chr8_37758588_37758772 0.18 RAB11FIP1
RAB11 family interacting protein 1 (class I)
1695
0.28
chr15_42415254_42415667 0.18 PLA2G4D
phospholipase A2, group IVD (cytosolic)
28708
0.13
chr10_98416000_98416373 0.18 PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
13182
0.2
chr2_75095702_75095909 0.18 HK2
hexokinase 2
33508
0.19
chr15_90755314_90755522 0.17 SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
9564
0.12
chr4_154576776_154576934 0.17 RP11-153M7.3

22556
0.19
chr1_22454794_22454972 0.17 WNT4
wingless-type MMTV integration site family, member 4
1461
0.43
chr3_185471276_185471520 0.17 ENSG00000265470
.
14294
0.21
chr6_90111426_90111593 0.17 RRAGD
Ras-related GTP binding D
10280
0.19
chr5_134769606_134770119 0.17 C5orf20
chromosome 5 open reading frame 20
13176
0.14
chr12_55276178_55276393 0.17 MUCL1
mucin-like 1
27964
0.2
chr2_121363772_121364036 0.17 ENSG00000201006
.
44945
0.19
chr8_82029068_82029440 0.17 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
4951
0.32
chr5_143522492_143522714 0.17 ENSG00000239390
.
2159
0.35
chr12_52099319_52099549 0.17 SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
19227
0.23
chr5_157661766_157661969 0.17 ENSG00000222626
.
257903
0.02
chr15_33735902_33736053 0.17 RYR3
ryanodine receptor 3
132800
0.05
chr20_58635186_58635347 0.16 C20orf197
chromosome 20 open reading frame 197
4286
0.29
chr8_142120178_142120491 0.16 DENND3
DENN/MADD domain containing 3
7043
0.22
chr3_37372099_37372250 0.16 ENSG00000222208
.
10966
0.2
chr8_62644087_62644326 0.16 ENSG00000264408
.
16859
0.22
chr8_72762424_72762575 0.16 MSC
musculin
5796
0.19
chr7_100411285_100411882 0.16 ENSG00000263672
.
7303
0.11
chr12_117514666_117514937 0.16 TESC
tescalcin
22450
0.23
chr17_46080195_46080690 0.16 RP11-6N17.10

6880
0.1
chr13_32822854_32823183 0.16 FRY
furry homolog (Drosophila)
15787
0.21
chrX_20413169_20413368 0.16 ENSG00000252978
.
56958
0.16
chr12_11962461_11962612 0.16 ETV6
ets variant 6
57101
0.16
chr13_81205127_81205302 0.16 ENSG00000202398
.
261545
0.02
chr8_48318969_48319120 0.16 SPIDR
scaffolding protein involved in DNA repair
33919
0.22
chr4_185179575_185179726 0.16 ENSG00000221523
.
8934
0.21
chr15_42801149_42801309 0.16 SNAP23
synaptosomal-associated protein, 23kDa
2816
0.19
chr6_44202164_44202547 0.16 SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
7479
0.11
chr12_54688458_54688720 0.16 NFE2
nuclear factor, erythroid 2
953
0.32
chr3_127487286_127487461 0.16 MGLL
monoglyceride lipase
15478
0.23
chr7_102631323_102631632 0.16 NFE4
nuclear factor, erythroid 4
17508
0.14
chr17_79879033_79879418 0.16 SIRT7
sirtuin 7
26
0.9
chr11_111394946_111395097 0.15 RP11-794P6.6

2459
0.16
chr6_6804228_6804533 0.15 ENSG00000240936
.
134750
0.05
chr14_92506646_92506800 0.15 TRIP11
thyroid hormone receptor interactor 11
320
0.87
chr1_203254365_203254586 0.15 BTG2
BTG family, member 2
20189
0.15
chr6_71958092_71958555 0.15 RP11-154D6.1

36312
0.16
chr1_239979756_239979955 0.15 CHRM3-AS1
CHRM3 antisense RNA 1
83317
0.09
chr8_59084985_59085323 0.15 FAM110B
family with sequence similarity 110, member B
178041
0.03
chr1_229721184_229721335 0.15 ABCB10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
26817
0.12
chr12_53428271_53428519 0.15 RP11-983P16.4

11392
0.11
chr2_29175143_29175407 0.15 FAM179A
family with sequence similarity 179, member A
4202
0.14
chr14_77872559_77872757 0.15 FKSG61

10083
0.11
chr13_53276312_53276509 0.15 LECT1
leukocyte cell derived chemotaxin 1
37077
0.16
chr11_10646945_10647096 0.15 MRVI1
murine retrovirus integration site 1 homolog
26712
0.15
chr21_46955498_46955649 0.15 SLC19A1
solute carrier family 19 (folate transporter), member 1
1044
0.57
chr6_18427248_18427399 0.15 ENSG00000238458
.
25040
0.2
chr3_30990444_30990685 0.15 GADL1
glutamate decarboxylase-like 1
54307
0.17
chr1_17636167_17636318 0.15 PADI4
peptidyl arginine deiminase, type IV
1550
0.36
chr5_146165960_146166111 0.15 ENSG00000265875
.
51637
0.15
chr3_182929018_182929169 0.15 B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
41939
0.13
chr3_46134937_46135139 0.15 XCR1
chemokine (C motif) receptor 1
65804
0.1
chr10_50568000_50568191 0.15 DRGX
dorsal root ganglia homeobox
31812
0.15
chr20_23095516_23095667 0.15 CD93
CD93 molecule
28614
0.15
chr8_95983279_95983772 0.15 NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
9636
0.15
chr8_48418684_48418835 0.15 RP11-697N18.4

21200
0.24
chr11_59571551_59571702 0.15 MRPL16
mitochondrial ribosomal protein L16
6147
0.16
chr3_108988791_108989046 0.15 ENSG00000252889
.
44942
0.15
chr4_84115690_84115841 0.15 PLAC8
placenta-specific 8
57537
0.13
chr7_117479656_117479807 0.15 CTTNBP2
cortactin binding protein 2
31961
0.24
chr12_7596853_7597078 0.15 CD163L1
CD163 molecule-like 1
184
0.96
chr1_199829495_199829849 0.15 ENSG00000200139
.
27615
0.24
chr5_157295124_157295340 0.15 CLINT1
clathrin interactor 1
9049
0.23
chr3_184304717_184305002 0.15 EPHB3
EPH receptor B3
25287
0.17
chr17_42761038_42761322 0.15 CCDC43
coiled-coil domain containing 43
5913
0.13
chr5_73729078_73729239 0.15 ENSG00000244326
.
115347
0.06
chr2_176326738_176326889 0.15 ENSG00000221347
.
131712
0.05
chr18_11918822_11919203 0.14 MPPE1
metallophosphoesterase 1
9790
0.14
chr16_81531821_81532117 0.14 CMIP
c-Maf inducing protein
3015
0.36
chr22_50347685_50347933 0.14 PIM3
pim-3 oncogene
6352
0.19
chr1_68027658_68027809 0.14 ENSG00000207504
.
20923
0.22
chr7_50258904_50259055 0.14 AC020743.2

76560
0.1
chr6_3139599_3139904 0.14 BPHL
biphenyl hydrolase-like (serine hydrolase)
908
0.5
chr13_77390552_77390953 0.14 KCTD12
potassium channel tetramerization domain containing 12
69773
0.11
chr2_223907840_223908197 0.14 KCNE4
potassium voltage-gated channel, Isk-related family, member 4
8514
0.28
chr2_54911007_54911158 0.14 AC093110.3

21153
0.19
chr4_37394628_37394820 0.14 C4orf19
chromosome 4 open reading frame 19
60839
0.15
chr6_6891304_6891524 0.14 ENSG00000240936
.
47716
0.18
chr6_13302166_13302317 0.14 RP1-257A7.4

6423
0.2
chr7_6474034_6474265 0.14 DAGLB
diacylglycerol lipase, beta
13414
0.16
chr5_88715552_88715703 0.14 MEF2C-AS1
MEF2C antisense RNA 1
1003
0.72
chr19_52141106_52141257 0.14 SIGLEC5
sialic acid binding Ig-like lectin 5
7593
0.11
chr7_97767382_97767616 0.14 LMTK2
lemur tyrosine kinase 2
31302
0.17
chr1_41975943_41976221 0.14 RP11-486B10.3

25032
0.17
chr1_95186096_95186247 0.14 ENSG00000263526
.
25285
0.23
chr2_169957115_169957325 0.14 AC007556.3

33
0.98
chr9_93570502_93570735 0.14 SYK
spleen tyrosine kinase
6409
0.34
chr3_14442673_14442824 0.14 SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
1328
0.49
chr14_93551916_93552209 0.14 ITPK1-AS1
ITPK1 antisense RNA 1
18265
0.18
chr6_130012897_130013130 0.14 ARHGAP18
Rho GTPase activating protein 18
18357
0.25
chr20_23128727_23129149 0.14 ENSG00000201527
.
12670
0.21
chr15_90562748_90563308 0.14 ENSG00000265871
.
13041
0.14
chr1_32123678_32123829 0.14 RP11-73M7.6

894
0.46
chr3_184293955_184294106 0.14 EPHB3
EPH receptor B3
14458
0.18
chr10_126758424_126758575 0.14 ENSG00000264572
.
37060
0.17
chr4_106035810_106035961 0.14 ENSG00000252136
.
8741
0.23
chr11_15923291_15923597 0.14 CTD-3096P4.1

121292
0.06
chr15_43522743_43522938 0.14 EPB42
erythrocyte membrane protein band 4.2
9359
0.13
chr8_56887528_56887788 0.14 ENSG00000240905
.
5438
0.18
chr15_50698058_50698434 0.14 USP8
ubiquitin specific peptidase 8
18331
0.14
chr2_38493865_38494016 0.14 ATL2
atlastin GTPase 2
109426
0.06
chr3_196280624_196280799 0.13 WDR53
WD repeat domain 53
13470
0.13
chr8_96220752_96221005 0.13 C8orf37
chromosome 8 open reading frame 37
60551
0.12
chr1_224097972_224098123 0.13 TP53BP2
tumor protein p53 binding protein, 2
64373
0.11
chr7_69368156_69368307 0.13 AUTS2
autism susceptibility candidate 2
303634
0.01
chr6_36524306_36524457 0.13 STK38
serine/threonine kinase 38
9134
0.15
chr20_2265960_2266140 0.13 TGM3
transglutaminase 3
10597
0.24
chr5_159743183_159743334 0.13 CCNJL
cyclin J-like
3651
0.22
chr5_3994179_3994446 0.13 CTD-2012M11.3

394010
0.01
chr3_15973999_15974271 0.13 ENSG00000207815
.
58857
0.13
chr3_45456350_45456693 0.13 LARS2
leucyl-tRNA synthetase 2, mitochondrial
26410
0.21
chr4_22609177_22609328 0.13 GPR125
G protein-coupled receptor 125
91575
0.1
chr12_29400868_29401019 0.13 FAR2
fatty acyl CoA reductase 2
24265
0.22
chr19_43057216_43057430 0.13 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
8063
0.19
chr9_78221708_78221880 0.13 ENSG00000238598
.
70029
0.13
chr9_94773267_94773418 0.13 ROR2
receptor tyrosine kinase-like orphan receptor 2
60898
0.13
chr20_2266440_2266591 0.13 TGM3
transglutaminase 3
10132
0.24
chr19_43849836_43850167 0.13 CD177
CD177 molecule
7824
0.17
chr3_67047069_67047341 0.13 KBTBD8
kelch repeat and BTB (POZ) domain containing 8
1522
0.59
chr4_39152584_39152984 0.13 RP11-360F5.1

24346
0.17
chr12_54688907_54689323 0.13 NFE2
nuclear factor, erythroid 2
427
0.65
chr1_10748665_10749049 0.13 CASZ1
castor zinc finger 1
43724
0.14
chr15_89710472_89711584 0.13 RLBP1
retinaldehyde binding protein 1
44046
0.12
chr2_25706012_25706163 0.13 AC104699.1

62101
0.13
chrX_39667886_39668149 0.13 ENSG00000264618
.
21940
0.22
chr14_24041269_24041503 0.13 JPH4
junctophilin 4
824
0.44
chr12_89555329_89555814 0.13 ENSG00000238302
.
120491
0.06
chr7_39740325_39740528 0.13 AC004837.5

2469
0.34
chr11_126041739_126041935 0.13 RP11-50B3.4

37085
0.1
chr3_16006227_16006629 0.13 ENSG00000207815
.
91150
0.08
chr17_56324893_56325185 0.13 LPO
lactoperoxidase
8963
0.13
chr20_58688912_58689063 0.13 C20orf197
chromosome 20 open reading frame 197
58007
0.14
chr2_121946677_121947036 0.13 TFCP2L1
transcription factor CP2-like 1
95927
0.08
chr2_192301147_192301752 0.13 MYO1B
myosin IB
25658
0.23
chr17_47590468_47590727 0.13 NGFR
nerve growth factor receptor
15844
0.14
chr2_111790938_111791089 0.13 ACOXL
acyl-CoA oxidase-like
46238
0.17
chr11_122263966_122264117 0.13 ENSG00000252776
.
55877
0.13
chr3_128312961_128313112 0.13 C3orf27
chromosome 3 open reading frame 27
18107
0.19
chr9_73196230_73196387 0.13 ENSG00000272232
.
1931
0.46
chr4_36313792_36313943 0.13 DTHD1
death domain containing 1
28223
0.2
chr1_247805569_247805720 0.13 RP11-978I15.10

1488
0.25
chr9_126319054_126319231 0.13 ENSG00000222722
.
28594
0.2
chr8_86983503_86983666 0.13 ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
15968
0.26
chr1_29111482_29111776 0.13 OPRD1
opioid receptor, delta 1
27025
0.15
chr10_101939847_101940043 0.13 ERLIN1
ER lipid raft associated 1
5841
0.15
chr7_41909046_41909309 0.13 AC005027.3

164244
0.04
chr1_26601413_26601689 0.13 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
4116
0.14
chr9_124222243_124222394 0.13 ENSG00000240299
.
34479
0.15
chr9_137248256_137248507 0.13 ENSG00000263897
.
22876
0.21
chr2_178213706_178213857 0.13 ENSG00000238295
.
3092
0.19
chr4_139875353_139875683 0.13 RP11-371F15.3

16383
0.2
chr2_89053827_89053978 0.13 ENSG00000221686
.
12933
0.13
chr2_240072595_240072746 0.13 HDAC4
histone deacetylase 4
4601
0.15
chr9_92771423_92771933 0.13 ENSG00000263967
.
14139
0.32
chr1_229294714_229294972 0.13 RP5-1061H20.5

68466
0.1
chr17_8693564_8693757 0.13 MFSD6L
major facilitator superfamily domain containing 6-like
9007
0.19
chr6_35002781_35002932 0.13 TCP11
t-complex 11, testis-specific
85966
0.08

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018101 protein citrullination(GO:0018101)
0.1 0.3 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.1 0.2 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.1 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.2 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0009415 response to water(GO:0009415)
0.0 0.2 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.2 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.1 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.0 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.2 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.0 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.2 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.0 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.0 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.1 GO:0042116 macrophage activation(GO:0042116)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.0 REACTOME MITOTIC G1 G1 S PHASES Genes involved in Mitotic G1-G1/S phases
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC