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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for EVX2

Z-value: 0.99

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Transcription factors associated with EVX2

Gene Symbol	Gene ID	Gene Info
EVX2 Ensembl NCBI GeneCards UniProt	ENSG00000174279.4	EVX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
EVX2	chr2_176932380_176932585	16159	0.098495	0.78	1.4e-02	Click!
EVX2	chr2_176945583_176945734	2983	0.131117	0.76	1.7e-02	Click!
EVX2	chr2_176947944_176948095	622	0.538477	0.74	2.2e-02	Click!
EVX2	chr2_176950582_176950733	2016	0.164980	0.73	2.6e-02	Click!
EVX2	chr2_176946726_176946982	1787	0.191724	0.72	3.0e-02	Click!

Activity of the EVX2 motif across conditions

Conditions sorted by the z-value of the EVX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_174862628_174862955	0.56	SP3	Sp3 transcription factor	32361	0.24
chr10_79021361_79021706	0.52	RP11-328K22.1		52166	0.15
chr7_41910301_41910559	0.51	AC005027.3		165497	0.04
chr1_173159483_173159962	0.51	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	14975	0.26
chr17_26498050_26498459	0.49	PYY2	peptide YY, 2 (pseudogene)	56078	0.09
chr11_10609627_10609795	0.49	MRVI1-AS1	MRVI1 antisense RNA 1	5033	0.19
chr18_54041028_54041261	0.46	TXNL1	thioredoxin-like 1	240578	0.02
chr2_86017810_86018001	0.44	AC105053.3		24348	0.13
chr20_40221307_40221497	0.42	CHD6	chromodomain helicase DNA binding protein 6	22010	0.23
chr3_12230073_12230226	0.42	TIMP4	TIMP metallopeptidase inhibitor 4	29298	0.22
chr13_33222085_33222352	0.41	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	61654	0.13
chr3_185538752_185538943	0.41	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	2	0.98
chr15_67006142_67006408	0.41	SMAD6	SMAD family member 6	2240	0.39
chrX_38728176_38728358	0.40	MID1IP1-AS1	MID1IP1 antisense RNA 1	65131	0.13
chr2_64881941_64882849	0.38	SERTAD2	SERTA domain containing 2	1348	0.52
chr2_163157595_163157835	0.38	IFIH1	interferon induced with helicase C domain 1	17479	0.19
chr3_5469487_5469638	0.37	ENSG00000241227	.	174654	0.03
chr16_85295971_85296292	0.36	ENSG00000266307	.	43800	0.16
chr5_138483370_138483521	0.36	SIL1	SIL1 nucleotide exchange factor	7711	0.22
chr5_111109748_111109899	0.34	NREP	neuronal regeneration related protein	15908	0.22
chr10_95236478_95236629	0.34	MYOF	myoferlin	5398	0.21
chr10_102813488_102813726	0.34	KAZALD1	Kazal-type serine peptidase inhibitor domain 1	7991	0.12
chr9_138952025_138952443	0.34	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	9808	0.22
chr8_121665009_121665299	0.33	RP11-713M15.1		108339	0.07
chr7_20071186_20071471	0.33	AC005062.2		28783	0.23
chr1_28797868_28798297	0.33	ENSG00000221216	.	9792	0.12
chr1_196578004_196578155	0.33	KCNT2	potassium channel, subfamily T, member 2	276	0.93
chr1_100976278_100976464	0.33	RP5-837M10.4		24818	0.19
chr11_122129149_122129397	0.33	RP11-716H6.2		36625	0.18
chr2_38046333_38046643	0.32	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	80877	0.1
chr5_112314540_112314973	0.32	DCP2	decapping mRNA 2	2277	0.32
chr18_72443447_72443598	0.32	ZNF407	zinc finger protein 407	100546	0.08
chr8_142158040_142158331	0.32	DENND3	DENN/MADD domain containing 3	6883	0.21
chr20_50419228_50419379	0.32	SALL4	spalt-like transcription factor 4	244	0.94
chr3_71862606_71862965	0.32	ENSG00000239250	.	13543	0.2
chr4_74571517_74571668	0.32	IL8	interleukin 8	34631	0.18
chr4_124476344_124476624	0.32	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	155361	0.04
chrX_10135860_10136222	0.31	CLCN4	chloride channel, voltage-sensitive 4	9469	0.24
chr6_15349427_15349643	0.31	ENSG00000201519	.	24832	0.19
chr12_111888065_111888216	0.31	ATXN2	ataxin 2	5776	0.19
chr12_1613825_1614060	0.31	WNT5B	wingless-type MMTV integration site family, member 5B	25115	0.21
chr3_148896549_148896700	0.31	CP	ceruloplasmin (ferroxidase)	784	0.67
chr7_135656817_135657003	0.30	MTPN	myotrophin	5154	0.19
chr11_61737024_61737182	0.30	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	1650	0.25
chr6_15897774_15897925	0.30	MYLIP	myosin regulatory light chain interacting protein	231507	0.02
chr4_130455151_130455302	0.30	ENSG00000222861	.	326429	0.01
chr2_71503166_71503343	0.30	PAIP2B	poly(A) binding protein interacting protein 2B	49041	0.12
chr6_37669094_37669483	0.30	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	2206	0.4
chr5_43208877_43209028	0.29	NIM1K	NIM1 serine/threonine protein kinase	15998	0.21
chr3_159902915_159903066	0.28	IL12A-AS1	IL12A antisense RNA 1	21889	0.18
chr18_74872232_74872572	0.28	MBP	myelin basic protein	27602	0.24
chr7_148320637_148320788	0.28	C7orf33	chromosome 7 open reading frame 33	33055	0.18
chr13_33836579_33836730	0.28	ENSG00000236581	.	8862	0.23
chr11_12767798_12767949	0.27	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	1285	0.56
chr11_94315586_94315737	0.27	PIWIL4	piwi-like RNA-mediated gene silencing 4	14804	0.19
chr22_38795449_38796163	0.27	CSNK1E	casein kinase 1, epsilon	1279	0.34
chr2_166451082_166451288	0.27	CSRNP3	cysteine-serine-rich nuclear protein 3	20566	0.27
chr2_235485735_235485886	0.27	ARL4C	ADP-ribosylation factor-like 4C	80113	0.12
chr13_77319833_77320172	0.26	KCTD12	potassium channel tetramerization domain containing 12	140523	0.05
chr16_53133154_53133539	0.26	CHD9	chromodomain helicase DNA binding protein 9	274	0.94
chr2_208116387_208116719	0.26	AC007879.5		2423	0.32
chr12_62525076_62525421	0.26	FAM19A2	family with sequence similarity 19 (chemokine (C-C motif)-like), member A2	4569	0.22
chr2_131100080_131100231	0.26	CCDC115	coiled-coil domain containing 115	233	0.56
chr2_216768664_216768815	0.26	ENSG00000212055	.	25097	0.24
chr16_85296592_85296743	0.26	ENSG00000266307	.	43264	0.16
chr11_69264697_69264848	0.26	CCND1	cyclin D1	191083	0.03
chr8_105598551_105598718	0.26	LRP12	low density lipoprotein receptor-related protein 12	2600	0.3
chr13_60026787_60027144	0.26	ENSG00000239003	.	27239	0.28
chr5_17413551_17413702	0.26	ENSG00000201715	.	67901	0.13
chr10_78983856_78984007	0.26	RP11-180I22.2		75881	0.1
chr7_75952019_75952170	0.25	HSPB1	heat shock 27kDa protein 1	19200	0.14
chr6_5828101_5828316	0.25	ENSG00000239472	.	90869	0.09
chr2_112368076_112368227	0.25	ENSG00000266063	.	160560	0.04
chr13_88323755_88324230	0.25	SLITRK5	SLIT and NTRK-like family, member 5	878	0.73
chr19_7268375_7268570	0.25	INSR	insulin receptor	25470	0.17
chr1_243896013_243896164	0.25	RP11-370K11.1		8035	0.27
chr9_95298761_95298917	0.25	ECM2	extracellular matrix protein 2, female organ and adipocyte specific	98	0.97
chr21_42579078_42579229	0.25	PLAC4	placenta-specific 4	20438	0.15
chr10_129704503_129704722	0.25	PTPRE	protein tyrosine phosphatase, receptor type, E	713	0.71
chr14_99502782_99502941	0.25	AL162151.4		121892	0.06
chr8_130906812_130906977	0.25	ENSG00000200075	.	25932	0.18
chr1_185066313_185066464	0.24	TRMT1L	tRNA methyltransferase 1 homolog (S. cerevisiae)-like	42304	0.13
chr9_110522175_110522455	0.24	AL162389.1	Uncharacterized protein	18104	0.2
chr20_52352229_52352983	0.24	ENSG00000238468	.	67309	0.12
chr1_206225703_206225865	0.24	AVPR1B	arginine vasopressin receptor 1B	1808	0.28
chr4_128619906_128620188	0.24	INTU	inturned planar cell polarity protein	11078	0.23
chr7_23030019_23030170	0.24	FAM126A	family with sequence similarity 126, member A	23599	0.23
chr6_12940320_12940471	0.23	PHACTR1	phosphatase and actin regulator 1	17819	0.29
chr1_116274836_116274987	0.23	CASQ2	calsequestrin 2 (cardiac muscle)	36424	0.18
chr1_225610187_225610435	0.23	LBR	lamin B receptor	5288	0.2
chr8_38238060_38238354	0.23	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	132	0.94
chr17_33873153_33873675	0.23	RP11-1094M14.12		6810	0.11
chr8_22949674_22949892	0.23	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	7915	0.13
chr2_55390382_55390533	0.23	RTN4	reticulon 4	50700	0.1
chr10_131682317_131682501	0.23	ENSG00000266676	.	40771	0.18
chr18_3015862_3016088	0.23	LPIN2	lipin 2	2662	0.24
chr3_151066517_151066717	0.23	P2RY13	purinergic receptor P2Y, G-protein coupled, 13	19281	0.16
chr2_168048837_168048988	0.23	XIRP2	xin actin-binding repeat containing 2	5119	0.31
chr6_35014782_35015029	0.23	TCP11	t-complex 11, testis-specific	73917	0.09
chr13_102302331_102302482	0.23	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	51911	0.17
chr10_15921921_15922072	0.23	ENSG00000239130	.	6361	0.25
chr17_62384463_62384614	0.22	TEX2	testis expressed 2	43877	0.13
chr1_238770348_238770644	0.22	ENSG00000252371	.	281408	0.01
chr8_99838628_99838779	0.22	STK3	serine/threonine kinase 3	794	0.74
chr6_30923154_30923376	0.22	HCG21	HLA complex group 21 (non-protein coding)	626	0.52
chr5_4199619_4199770	0.22	CTD-2012M11.3		599392	0.0
chr6_161525948_161526099	0.22	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	44298	0.18
chr6_134238115_134238266	0.22	RP3-323P13.2		25116	0.18
chr2_161236579_161237045	0.22	ENSG00000252465	.	16667	0.2
chr5_73839209_73839360	0.22	HEXB	hexosaminidase B (beta polypeptide)	96564	0.07
chr8_122257591_122257742	0.21	ENSG00000221644	.	58534	0.16
chr2_44576037_44576404	0.21	PREPL	prolyl endopeptidase-like	10668	0.2
chr1_8271781_8272061	0.21	ENSG00000200975	.	5264	0.25
chr22_24908185_24908422	0.21	AP000355.2		4173	0.16
chr4_95454799_95455193	0.21	PDLIM5	PDZ and LIM domain 5	10120	0.32
chr5_135394625_135394981	0.21	TGFBI	transforming growth factor, beta-induced, 68kDa	72	0.98
chr2_159955686_159955837	0.21	ENSG00000202029	.	72107	0.11
chr1_9301737_9301925	0.21	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	1928	0.34
chr7_16851610_16851761	0.21	AGR2	anterior gradient 2	6981	0.2
chr3_111717564_111717859	0.21	TAGLN3	transgelin 3	69	0.97
chr5_136899227_136899378	0.20	ENSG00000221612	.	30159	0.2
chr4_139943173_139943324	0.20	ENSG00000264953	.	4515	0.17
chr7_29247042_29247209	0.20	AC004593.3		1461	0.41
chr14_101178681_101178832	0.20	DLK1	delta-like 1 homolog (Drosophila)	13286	0.12
chr19_954292_954443	0.20	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	21858	0.07
chr14_105749762_105749913	0.20	BRF1	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	16968	0.15
chr1_231493802_231494072	0.20	SPRTN	SprT-like N-terminal domain	18764	0.17
chr8_19213262_19213413	0.20	SH2D4A	SH2 domain containing 4A	36236	0.23
chr14_60671402_60671553	0.20	DHRS7	dehydrogenase/reductase (SDR family) member 7	34903	0.15
chr7_138660539_138660690	0.20	KIAA1549	KIAA1549	5450	0.26
chr4_120580539_120580789	0.20	PDE5A	phosphodiesterase 5A, cGMP-specific	30518	0.22
chr6_56591218_56591369	0.19	DST	dystonin	59384	0.15
chr2_102914112_102914534	0.19	IL1RL1	interleukin 1 receptor-like 1	13639	0.19
chr3_137930306_137930457	0.19	ARMC8	armadillo repeat containing 8	12097	0.21
chr22_29641192_29641343	0.19	EMID1	EMI domain containing 1	14260	0.11
chr5_150861749_150861900	0.19	ENSG00000200227	.	4686	0.19
chr8_70583516_70583667	0.19	ENSG00000222889	.	28868	0.19
chr12_65369994_65370192	0.19	ENSG00000221564	.	37290	0.18
chr6_26485415_26485566	0.19	BTN1A1	butyrophilin, subfamily 1, member A1	15959	0.11
chr9_128517768_128517919	0.19	PBX3	pre-B-cell leukemia homeobox 3	7365	0.28
chr8_33325166_33325317	0.19	FUT10	fucosyltransferase 10 (alpha (1,3) fucosyltransferase)	5396	0.18
chr5_34519672_34519823	0.19	RAI14	retinoic acid induced 14	136595	0.05
chr7_81620419_81620570	0.19	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	14612	0.22
chr14_54913534_54913685	0.19	CNIH1	cornichon family AMPA receptor auxiliary protein 1	5460	0.23
chr6_157758656_157758807	0.19	TMEM242	transmembrane protein 242	14098	0.22
chr3_155926514_155926665	0.19	KCNAB1-AS2	KCNAB1 antisense RNA 2	19083	0.25
chr17_64467443_64467600	0.19	RP11-4F22.2		54549	0.14
chr17_59327352_59327704	0.18	RP11-136H19.1		114203	0.05
chr14_77873001_77873391	0.18	FKSG61		9545	0.11
chr15_56439129_56439280	0.18	RFX7	regulatory factor X, 7	42880	0.17
chr5_139090606_139090882	0.18	ENSG00000200756	.	6931	0.21
chr4_173934863_173935106	0.18	ENSG00000241652	.	127810	0.05
chr2_18733477_18733628	0.18	RDH14	retinol dehydrogenase 14 (all-trans/9-cis/11-cis)	8394	0.2
chr14_103046146_103046463	0.18	ENSG00000239224	.	3210	0.22
chr9_110473577_110473728	0.18	ENSG00000202308	.	48125	0.15
chr4_186629734_186630027	0.18	ENSG00000207497	.	1241	0.48
chr4_26220381_26220779	0.18	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	53649	0.18
chr6_146866872_146867091	0.18	RAB32	RAB32, member RAS oncogene family	2152	0.41
chr5_74615457_74615613	0.18	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	16619	0.19
chr3_105699405_105699556	0.18	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	111084	0.08
chr22_25799352_25799559	0.18	LRP5L	low density lipoprotein receptor-related protein 5-like	1889	0.35
chr3_24630898_24631049	0.18	ENSG00000265028	.	68047	0.12
chr11_75561572_75561825	0.18	UVRAG	UV radiation resistance associated	11709	0.12
chr10_104557046_104557197	0.18	ENSG00000252994	.	6565	0.14
chr5_173293788_173294026	0.18	CPEB4	cytoplasmic polyadenylation element binding protein 4	21376	0.25
chr13_27597624_27597775	0.18	USP12-AS1	USP12 antisense RNA 1	139293	0.04
chr12_65684698_65684849	0.18	RP11-305O6.3		9336	0.23
chr1_116185862_116186059	0.18	VANGL1	VANGL planar cell polarity protein 1	710	0.71
chr12_32609742_32609949	0.18	ENSG00000253063	.	20560	0.2
chr11_114129904_114130134	0.17	NNMT	nicotinamide N-methyltransferase	1466	0.5
chr12_25653663_25653956	0.17	IFLTD1	intermediate filament tail domain containing 1	19086	0.25
chr2_63926133_63926284	0.17	ENSG00000221085	.	3539	0.34
chr14_89633575_89633726	0.17	FOXN3	forkhead box N3	13438	0.28
chr10_173434_173996	0.17	ZMYND11	zinc finger, MYND-type containing 11	6690	0.24
chr11_112193182_112193453	0.17	ENSG00000206772	.	30068	0.14
chr9_16828594_16828745	0.17	BNC2	basonuclin 2	3617	0.36
chr6_114017168_114017357	0.17	ENSG00000221559	.	8773	0.26
chr11_117958729_117958938	0.17	TMPRSS4-AS1	TMPRSS4 antisense RNA 1	1325	0.38
chr12_89033164_89033405	0.17	ENSG00000252850	.	57868	0.14
chr3_116583241_116583392	0.17	ENSG00000265433	.	14102	0.25
chr3_111623515_111623944	0.17	PHLDB2	pleckstrin homology-like domain, family B, member 2	6728	0.26
chr19_42315524_42315845	0.17	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	14599	0.11
chr17_58383468_58383619	0.17	USP32	ubiquitin specific peptidase 32	49482	0.13
chr20_52211917_52212263	0.17	ZNF217	zinc finger protein 217	1712	0.38
chr1_33115546_33115708	0.17	ZBTB8OS	zinc finger and BTB domain containing 8 opposite strand	534	0.62
chrX_131614461_131614831	0.17	MBNL3	muscleblind-like splicing regulator 3	8397	0.3
chr21_30503482_30503633	0.17	MAP3K7CL	MAP3K7 C-terminal like	21	0.97
chr11_88078061_88078240	0.17	CTSC	cathepsin C	7195	0.31
chr6_20484087_20484358	0.17	ENSG00000201683	.	16184	0.16
chr1_178102702_178103151	0.17	RASAL2	RAS protein activator like 2	39650	0.22
chr20_48955704_48955952	0.17	ENSG00000244376	.	90192	0.08
chr5_123149843_123149994	0.17	CSNK1G3	casein kinase 1, gamma 3	225799	0.02
chr1_205206462_205206644	0.17	RP11-383G10.5		558	0.73
chr6_11912233_11912384	0.16	RP11-456H18.1		79937	0.1
chr17_47440332_47440604	0.16	ZNF652	zinc finger protein 652	633	0.61
chr12_56027127_56027278	0.16	OR10P1	olfactory receptor, family 10, subfamily P, member 1	3442	0.14
chr3_99764961_99765177	0.16	FILIP1L	filamin A interacting protein 1-like	68288	0.1
chr2_144712590_144712741	0.16	AC016910.1		18025	0.25
chr8_80226395_80226546	0.16	ENSG00000264969	.	216872	0.02
chr5_126306662_126306822	0.16	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	52822	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of EVX2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.0	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.0	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.0	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.3	GO:0005614	interstitial matrix(GO:0005614)
0.1	GO:0033268	node of Ranvier(GO:0033268)
0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.1	GO:0071547	piP-body(GO:0071547)
0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.1	GO:0030056	hemidesmosome(GO:0030056)
0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	GO:0030315	T-tubule(GO:0030315)
0.1	GO:0071778	obsolete WINAC complex(GO:0071778)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	REACTOME SIGNALLING TO ERKS	Genes involved in Signalling to ERKs
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors