Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for FOSL1

Z-value: 2.28

Motif logo

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
ENSG00000175592.4 FOS like 1, AP-1 transcription factor subunit

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_65664455_65664606FOSL133600.0980640.862.7e-03Click!
chr11_65664209_65664360FOSL136060.0945590.863.0e-03Click!
chr11_65663224_65663375FOSL145910.0852630.863.3e-03Click!
chr11_65670447_65670677FOSL125180.1201860.835.5e-03Click!
chr11_65663028_65663179FOSL147870.0839730.752.0e-02Click!

Activity of the FOSL1 motif across conditions

Conditions sorted by the z-value of the FOSL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_23946972_23947800 1.56 PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
55686
0.17
chr15_74688962_74689487 1.12 CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
29143
0.11
chr17_45343433_45343839 1.03 ENSG00000238419
.
6850
0.14
chr9_97567295_97567893 0.94 ENSG00000252153
.
4650
0.2
chr2_231481752_231482027 0.90 ENSG00000199791
.
30053
0.17
chr16_84211484_84211635 0.89 DNAAF1
dynein, axonemal, assembly factor 1
1812
0.22
chr2_208497932_208498495 0.87 METTL21A
methyltransferase like 21A
7562
0.19
chr15_74281262_74281725 0.85 STOML1
stomatin (EPB72)-like 1
2682
0.22
chr22_18539696_18539847 0.83 XXbac-B476C20.9

20792
0.13
chr6_7640858_7641250 0.82 SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
50622
0.15
chr8_41009338_41009489 0.82 ENSG00000206867
.
119002
0.05
chr6_44002412_44002760 0.80 ENSG00000265518
.
21848
0.15
chr11_69069495_69070094 0.80 MYEOV
myeloma overexpressed
8169
0.29
chr4_5640825_5640976 0.77 EVC2
Ellis van Creveld syndrome 2
69394
0.11
chr22_46402793_46403252 0.77 WNT7B
wingless-type MMTV integration site family, member 7B
30013
0.1
chr3_13394182_13394652 0.76 NUP210
nucleoporin 210kDa
67392
0.12
chr18_47257660_47257811 0.76 ACAA2
acetyl-CoA acyltransferase 2
80166
0.07
chr10_121438025_121438176 0.75 BAG3
BCL2-associated athanogene 3
21978
0.2
chr1_93804419_93804570 0.75 ENSG00000223745
.
406
0.85
chr6_10633412_10633876 0.75 GCNT6
glucosaminyl (N-acetyl) transferase 6
349
0.86
chr10_79273704_79273855 0.74 ENSG00000199592
.
73028
0.11
chr16_70780334_70780534 0.74 RP11-394B2.6

526
0.69
chr16_88298714_88299235 0.74 ZNF469
zinc finger protein 469
194905
0.02
chr1_17559878_17560367 0.74 PADI1
peptidyl arginine deiminase, type I
272
0.9
chr16_72405306_72405606 0.73 ENSG00000207514
.
5147
0.31
chr22_27288381_27288532 0.72 ENSG00000200443
.
143394
0.05
chr6_43090954_43091105 0.72 PTK7
protein tyrosine kinase 7
7300
0.13
chr21_43084452_43084603 0.71 LINC00112
long intergenic non-protein coding RNA 112
52069
0.12
chr5_52105602_52106304 0.71 CTD-2288O8.1

22093
0.18
chr5_79252169_79252320 0.71 RP11-168A11.1

19842
0.2
chr5_96126842_96126993 0.71 CTD-2260A17.1

6253
0.15
chr7_101596135_101596475 0.70 CTB-181H17.1

7091
0.26
chr2_235959120_235959271 0.70 SH3BP4
SH3-domain binding protein 4
55711
0.18
chr2_191714503_191714827 0.70 GLS
glutaminase
30888
0.18
chr10_104103101_104103252 0.68 NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
50691
0.08
chr9_84174156_84174449 0.68 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
54135
0.17
chr1_94430357_94430508 0.67 ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
46749
0.13
chr16_80307677_80307828 0.67 DYNLRB2
dynein, light chain, roadblock-type 2
266879
0.02
chr1_230226034_230226185 0.66 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
23091
0.22
chr2_121266505_121266656 0.66 LINC01101
long intergenic non-protein coding RNA 1101
42883
0.19
chr5_65107256_65107407 0.66 NLN
neurolysin (metallopeptidase M3 family)
23141
0.22
chr3_119854481_119854726 0.65 ENSG00000244139
.
13847
0.18
chr8_23275057_23275208 0.64 LOXL2
lysyl oxidase-like 2
7672
0.19
chr2_36791072_36791223 0.64 AC007401.2
Uncharacterized protein
11736
0.19
chr2_28384161_28384312 0.64 AC093690.1

149090
0.04
chr9_101250638_101250789 0.64 GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
220766
0.02
chr6_110008406_110008557 0.64 AK9
adenylate kinase 9
3228
0.27
chr4_102077826_102078189 0.63 ENSG00000221265
.
173564
0.03
chr16_29302364_29302928 0.63 RP11-231C14.6

21025
0.17
chr11_74398613_74398764 0.63 ENSG00000223202
.
2419
0.21
chr8_126667741_126667892 0.63 ENSG00000266452
.
211009
0.02
chr3_71651118_71651323 0.62 FOXP1
forkhead box P1
18080
0.2
chr15_70719035_70719186 0.62 ENSG00000200216
.
233535
0.02
chr22_36863560_36864238 0.62 TXN2
thioredoxin 2
13488
0.14
chr2_197200446_197200597 0.62 HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
26425
0.19
chr2_238775076_238775227 0.62 ENSG00000263723
.
3396
0.24
chr18_28779535_28779686 0.61 DSC1
desmocollin 1
36791
0.15
chr2_182819845_182819996 0.61 PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
30631
0.17
chr11_45684848_45684999 0.61 CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
2249
0.32
chr2_217290932_217291083 0.61 SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
2492
0.24
chr3_185450101_185450459 0.61 C3orf65
chromosome 3 open reading frame 65
19200
0.2
chr12_11733022_11733284 0.61 ENSG00000251747
.
33740
0.16
chr5_14268406_14268609 0.60 TRIO
trio Rho guanine nucleotide exchange factor
22579
0.28
chr11_130595850_130596001 0.60 C11orf44
chromosome 11 open reading frame 44
53074
0.17
chr8_23654560_23654711 0.60 ENSG00000207027
.
9255
0.19
chr8_22602219_22602370 0.60 ENSG00000253125
.
2722
0.25
chr11_108908959_108909110 0.60 ENSG00000201243
.
32790
0.23
chr20_49982186_49982337 0.59 ENSG00000263645
.
11597
0.27
chr11_2934551_2934724 0.59 SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
9667
0.12
chr6_17981901_17982056 0.59 KIF13A
kinesin family member 13A
5716
0.3
chr8_18672049_18672314 0.58 ENSG00000251963
.
5045
0.25
chr6_41680801_41681561 0.58 RP11-298J23.5

6953
0.13
chr11_34366304_34366455 0.58 ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
12423
0.26
chr3_65941769_65941920 0.57 MAGI1-IT1
MAGI1 intronic transcript 1 (non-protein coding)
1611
0.39
chr13_110903096_110903247 0.57 COL4A2
collagen, type IV, alpha 2
54988
0.14
chr16_54111137_54111413 0.57 RP11-357N13.1

22780
0.19
chr2_20768919_20769070 0.57 HS1BP3-IT1
HS1BP3 intronic transcript 1 (non-protein coding)
23314
0.2
chr3_57094594_57094897 0.57 SPATA12
spermatogenesis associated 12
276
0.91
chr1_31229795_31230155 0.57 LAPTM5
lysosomal protein transmembrane 5
692
0.65
chr6_110538771_110539057 0.57 CDC40
cell division cycle 40
37290
0.17
chr10_29760583_29760940 0.57 SVIL
supervillin
24686
0.2
chr17_13447545_13447833 0.56 ENSG00000221698
.
726
0.71
chr22_37960029_37960180 0.56 CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
309
0.83
chr9_84106067_84106472 0.56 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
122168
0.06
chr1_113007807_113007958 0.56 WNT2B
wingless-type MMTV integration site family, member 2B
1281
0.49
chr11_128733246_128733397 0.56 KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
3855
0.23
chr3_45174222_45174373 0.56 CDCP1
CUB domain containing protein 1
13617
0.22
chr10_104364228_104364579 0.56 ENSG00000207029
.
13122
0.16
chr6_11771736_11771887 0.56 ADTRP
androgen-dependent TFPI-regulating protein
7225
0.29
chr1_218548529_218548680 0.56 TGFB2
transforming growth factor, beta 2
29027
0.19
chr18_421940_422183 0.55 RP11-720L2.2

2355
0.36
chr2_86019950_86020101 0.55 AC105053.3

22228
0.13
chr1_215277672_215277823 0.55 KCNK2
potassium channel, subfamily K, member 2
20887
0.3
chr1_207013289_207013440 0.55 IL19
interleukin 19
11142
0.16
chrX_48323593_48323869 0.55 SLC38A5
solute carrier family 38, member 5
2149
0.21
chr5_73839036_73839187 0.55 HEXB
hexosaminidase B (beta polypeptide)
96737
0.07
chr6_43978405_43978700 0.55 ENSG00000265518
.
2186
0.27
chr2_204357721_204357872 0.55 RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
2280
0.42
chr15_73988384_73988728 0.54 CD276
CD276 molecule
3425
0.28
chr2_20696028_20696179 0.54 ENSG00000200829
.
15498
0.21
chr12_6388900_6389082 0.54 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
30611
0.12
chr5_171810242_171810393 0.54 SH3PXD2B
SH3 and PX domains 2B
32927
0.17
chr19_4377112_4377465 0.54 SH3GL1
SH3-domain GRB2-like 1
3001
0.11
chr13_99804178_99804329 0.54 UBAC2
UBA domain containing 2
48775
0.12
chr7_129536508_129536659 0.53 UBE2H
ubiquitin-conjugating enzyme E2H
54584
0.09
chr8_123193136_123193287 0.53 ENSG00000238901
.
490319
0.0
chr1_172321665_172322022 0.53 ENSG00000252354
.
4560
0.2
chr13_31393568_31393719 0.53 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
83998
0.08
chr6_113371549_113371725 0.53 ENSG00000201386
.
78942
0.12
chr9_79175718_79175869 0.53 ENSG00000241781
.
10938
0.26
chr21_39832528_39832820 0.53 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
37671
0.22
chr7_71334038_71334189 0.52 ENSG00000201014
.
44728
0.21
chr11_859519_859810 0.52 RP11-1391J7.1

131
0.9
chr20_10020938_10021230 0.52 SNAP25-AS1
SNAP25 antisense RNA 1
5112
0.21
chr8_59664911_59665062 0.52 ENSG00000201231
.
62125
0.13
chr8_81170320_81170792 0.52 ENSG00000265588
.
16932
0.2
chr1_31870163_31870721 0.52 SERINC2
serine incorporator 2
11970
0.15
chr6_17968495_17968754 0.52 KIF13A
kinesin family member 13A
19070
0.26
chr7_129650015_129650166 0.52 RP11-306G20.1

1396
0.32
chr8_143757384_143757535 0.52 PSCA
prostate stem cell antigen
4415
0.13
chr1_28765982_28766202 0.52 PHACTR4
phosphatase and actin regulator 4
1410
0.33
chr2_121487319_121487470 0.51 GLI2
GLI family zinc finger 2
6429
0.31
chr15_76236352_76236503 0.51 FBXO22
F-box protein 22
11286
0.19
chr13_110492530_110492868 0.51 IRS2
insulin receptor substrate 2
53784
0.15
chr3_23609408_23609644 0.51 ENSG00000252562
.
45724
0.16
chr22_27872802_27872953 0.51 RP11-375H17.1

239591
0.02
chr17_41613704_41613971 0.51 ETV4
ets variant 4
6035
0.15
chr2_25570321_25570568 0.51 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
4985
0.24
chr12_3277713_3277864 0.51 TSPAN9-IT1
TSPAN9 intronic transcript 1 (non-protein coding)
18825
0.21
chr12_132385199_132385350 0.51 ULK1
unc-51 like autophagy activating kinase 1
5761
0.18
chr19_35611938_35612089 0.51 FXYD3
FXYD domain containing ion transport regulator 3
1746
0.19
chr12_109089080_109089525 0.51 CORO1C
coronin, actin binding protein, 1C
876
0.54
chr4_74140546_74140697 0.50 ENSG00000221639
.
10944
0.19
chr2_153271980_153272131 0.50 FMNL2
formin-like 2
80304
0.11
chr1_206897327_206897801 0.50 ENSG00000199349
.
23873
0.13
chr12_56120404_56120555 0.50 CD63
CD63 molecule
364
0.7
chr21_33836630_33836895 0.50 EVA1C
eva-1 homolog C (C. elegans)
36120
0.13
chr7_137457647_137457798 0.50 DGKI
diacylglycerol kinase, iota
73560
0.12
chr4_10097090_10097875 0.50 ENSG00000264931
.
17166
0.14
chr8_132857612_132857763 0.50 EFR3A
EFR3 homolog A (S. cerevisiae)
58648
0.16
chr6_151358211_151358362 0.50 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
176
0.94
chr17_40476887_40477238 0.50 STAT5A
signal transducer and activator of transcription 5A
18874
0.12
chr1_59943114_59943265 0.50 FGGY
FGGY carbohydrate kinase domain containing
76401
0.12
chr15_75954147_75954338 0.50 SNX33
sorting nexin 33
12145
0.09
chr14_75355002_75355210 0.50 DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
6447
0.15
chr17_60780537_60780688 0.50 RP11-156L14.1

2955
0.22
chr1_156083605_156084089 0.50 LMNA
lamin A/C
614
0.59
chr18_43344332_43344486 0.49 RP11-116O18.3

17229
0.18
chr6_56514356_56514539 0.49 DST
dystonin
6653
0.32
chr11_67917649_67917930 0.49 CTD-2655K5.1

20524
0.14
chr4_182880871_182881022 0.49 ENSG00000251742
.
124685
0.06
chr7_135430284_135430435 0.49 FAM180A
family with sequence similarity 180, member A
3101
0.22
chr20_30198397_30198778 0.49 ENSG00000264395
.
3598
0.15
chr19_2503776_2503986 0.49 ENSG00000252962
.
742
0.61
chr6_100731277_100731428 0.49 RP1-121G13.2

143642
0.05
chr4_139819017_139819168 0.49 RP11-371F15.3

40043
0.17
chr17_47533894_47534339 0.49 NGFR
nerve growth factor receptor
38539
0.1
chr15_56201396_56201579 0.49 NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
6365
0.26
chr20_30398171_30398354 0.49 MYLK2
myosin light chain kinase 2
8849
0.15
chr4_1331225_1331376 0.49 UVSSA
UV-stimulated scaffold protein A
9754
0.13
chr14_69506117_69506268 0.49 ACTN1-AS1
ACTN1 antisense RNA 1
59434
0.12
chr6_20877758_20877909 0.48 RP3-348I23.2

76908
0.12
chr13_96161803_96162207 0.48 CLDN10-AS1
CLDN10 antisense RNA 1
24159
0.21
chr19_45601288_45601848 0.48 PPP1R37
protein phosphatase 1, regulatory subunit 37
5136
0.1
chr4_95470032_95470452 0.48 PDLIM5
PDZ and LIM domain 5
25366
0.27
chr19_43239918_43240069 0.48 PSG3
pregnancy specific beta-1-glycoprotein 3
4636
0.24
chr20_19865364_19865598 0.48 RIN2
Ras and Rab interactor 2
1684
0.48
chr3_88857018_88857169 0.48 EPHA3
EPH receptor A3
299581
0.01
chr11_19944459_19944610 0.48 NAV2-AS3
NAV2 antisense RNA 3
58349
0.14
chr17_79392708_79392859 0.48 RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
12613
0.1
chr7_139138466_139138617 0.48 ENSG00000252332
.
5055
0.21
chr14_51403055_51403266 0.48 PYGL
phosphorylase, glycogen, liver
8014
0.19
chr5_77175661_77175812 0.48 TBCA
tubulin folding cofactor A
11132
0.3
chr3_168823031_168823291 0.47 MECOM
MDS1 and EVI1 complex locus
22661
0.28
chr7_55177396_55177547 0.47 EGFR
epidermal growth factor receptor
55
0.99
chr2_54998328_54998479 0.47 AC104781.1

22862
0.2
chr18_42749036_42749187 0.47 RP11-846C15.2

11968
0.26
chr2_38007244_38007545 0.47 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
41783
0.19
chr22_38624639_38624924 0.47 RP1-5O6.5

2545
0.16
chr20_11375066_11375217 0.47 C20orf187
chromosome 20 open reading frame 187
366330
0.01
chr10_12762810_12762961 0.47 ENSG00000221331
.
4467
0.33
chr14_95008607_95008758 0.47 SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
18746
0.14
chr2_225010855_225011006 0.47 ENSG00000211987
.
93343
0.08
chr11_65678995_65679525 0.47 C11orf68
chromosome 11 open reading frame 68
6571
0.08
chr2_9713569_9713720 0.47 ADAM17
ADAM metallopeptidase domain 17
17723
0.16
chr21_33896071_33896222 0.47 ENSG00000252045
.
14463
0.16
chr16_75297374_75297525 0.47 BCAR1
breast cancer anti-estrogen resistance 1
865
0.52
chr19_2028762_2028950 0.47 AC007136.1

2194
0.17
chr9_130326042_130326221 0.47 FAM129B
family with sequence similarity 129, member B
5236
0.19
chr3_170435229_170435380 0.47 RP11-373E16.3

60953
0.13
chr10_5631913_5632190 0.47 ENSG00000240577
.
41375
0.11
chr17_28848013_28848164 0.47 TBC1D29
TBC1 domain family, member 29
36042
0.12
chr11_60686848_60686999 0.47 TMEM109
transmembrane protein 109
227
0.84
chr17_46045289_46045440 0.47 CDK5RAP3
CDK5 regulatory subunit associated protein 3
188
0.88
chr19_38531152_38531303 0.47 ENSG00000221258
.
13378
0.17
chr7_1196429_1196848 0.47 ZFAND2A
zinc finger, AN1-type domain 2A
730
0.57
chr5_149265721_149265872 0.46 PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
53218
0.1
chr9_124044825_124044976 0.46 RP11-477J21.6

108
0.95
chr14_105147313_105147511 0.46 ENSG00000265291
.
3326
0.17
chr1_209780440_209781046 0.46 LAMB3
laminin, beta 3
11400
0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0018101 protein citrullination(GO:0018101)
0.2 0.7 GO:0070141 response to UV-A(GO:0070141)
0.2 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1 0.3 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.2 GO:0071732 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.1 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.1 0.2 GO:0021508 floor plate formation(GO:0021508)
0.1 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.2 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.1 GO:0090030 regulation of glucocorticoid biosynthetic process(GO:0031946) regulation of steroid hormone biosynthetic process(GO:0090030)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.2 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.2 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.2 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.2 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.1 0.1 GO:0042637 catagen(GO:0042637)
0.1 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0042663 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.2 GO:0010224 response to UV-B(GO:0010224)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.2 GO:0048641 regulation of skeletal muscle tissue development(GO:0048641)
0.0 0.2 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0045713 low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.3 GO:0090200 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0032373 positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0 0.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0071331 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0042635 positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.2 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0042754 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.4 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.0 GO:0032488 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.0 GO:0006390 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.3 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.0 0.1 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.1 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.0 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.8 GO:0007565 female pregnancy(GO:0007565)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.0 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.0 GO:0034763 negative regulation of transmembrane transport(GO:0034763) negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.0 GO:0051154 negative regulation of striated muscle cell differentiation(GO:0051154)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.3 GO:0042599 lamellar body(GO:0042599)
0.1 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:1902562 H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.0 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.3 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.1 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins