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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOSL1

Z-value: 2.28

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Transcription factors associated with FOSL1

Gene Symbol	Gene ID	Gene Info
FOSL1 Ensembl NCBI GeneCards UniProt	ENSG00000175592.4	FOSL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FOSL1	chr11_65664455_65664606	3360	0.098064	0.86	2.7e-03	Click!
FOSL1	chr11_65664209_65664360	3606	0.094559	0.86	3.0e-03	Click!
FOSL1	chr11_65663224_65663375	4591	0.085263	0.86	3.3e-03	Click!
FOSL1	chr11_65670447_65670677	2518	0.120186	0.83	5.5e-03	Click!
FOSL1	chr11_65663028_65663179	4787	0.083973	0.75	2.0e-02	Click!

Activity of the FOSL1 motif across conditions

Conditions sorted by the z-value of the FOSL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_23946972_23947800	1.56	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	55686	0.17
chr15_74688962_74689487	1.12	CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	29143	0.11
chr17_45343433_45343839	1.03	ENSG00000238419	.	6850	0.14
chr9_97567295_97567893	0.94	ENSG00000252153	.	4650	0.2
chr2_231481752_231482027	0.90	ENSG00000199791	.	30053	0.17
chr16_84211484_84211635	0.89	DNAAF1	dynein, axonemal, assembly factor 1	1812	0.22
chr2_208497932_208498495	0.87	METTL21A	methyltransferase like 21A	7562	0.19
chr15_74281262_74281725	0.85	STOML1	stomatin (EPB72)-like 1	2682	0.22
chr22_18539696_18539847	0.83	XXbac-B476C20.9		20792	0.13
chr6_7640858_7641250	0.82	SNRNP48	small nuclear ribonucleoprotein 48kDa (U11/U12)	50622	0.15
chr8_41009338_41009489	0.82	ENSG00000206867	.	119002	0.05
chr6_44002412_44002760	0.80	ENSG00000265518	.	21848	0.15
chr11_69069495_69070094	0.80	MYEOV	myeloma overexpressed	8169	0.29
chr4_5640825_5640976	0.77	EVC2	Ellis van Creveld syndrome 2	69394	0.11
chr22_46402793_46403252	0.77	WNT7B	wingless-type MMTV integration site family, member 7B	30013	0.1
chr3_13394182_13394652	0.76	NUP210	nucleoporin 210kDa	67392	0.12
chr18_47257660_47257811	0.76	ACAA2	acetyl-CoA acyltransferase 2	80166	0.07
chr10_121438025_121438176	0.75	BAG3	BCL2-associated athanogene 3	21978	0.2
chr1_93804419_93804570	0.75	ENSG00000223745	.	406	0.85
chr6_10633412_10633876	0.75	GCNT6	glucosaminyl (N-acetyl) transferase 6	349	0.86
chr10_79273704_79273855	0.74	ENSG00000199592	.	73028	0.11
chr16_70780334_70780534	0.74	RP11-394B2.6		526	0.69
chr16_88298714_88299235	0.74	ZNF469	zinc finger protein 469	194905	0.02
chr1_17559878_17560367	0.74	PADI1	peptidyl arginine deiminase, type I	272	0.9
chr16_72405306_72405606	0.73	ENSG00000207514	.	5147	0.31
chr22_27288381_27288532	0.72	ENSG00000200443	.	143394	0.05
chr6_43090954_43091105	0.72	PTK7	protein tyrosine kinase 7	7300	0.13
chr21_43084452_43084603	0.71	LINC00112	long intergenic non-protein coding RNA 112	52069	0.12
chr5_52105602_52106304	0.71	CTD-2288O8.1		22093	0.18
chr5_79252169_79252320	0.71	RP11-168A11.1		19842	0.2
chr5_96126842_96126993	0.71	CTD-2260A17.1		6253	0.15
chr7_101596135_101596475	0.70	CTB-181H17.1		7091	0.26
chr2_235959120_235959271	0.70	SH3BP4	SH3-domain binding protein 4	55711	0.18
chr2_191714503_191714827	0.70	GLS	glutaminase	30888	0.18
chr10_104103101_104103252	0.68	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	50691	0.08
chr9_84174156_84174449	0.68	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	54135	0.17
chr1_94430357_94430508	0.67	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	46749	0.13
chr16_80307677_80307828	0.67	DYNLRB2	dynein, light chain, roadblock-type 2	266879	0.02
chr1_230226034_230226185	0.66	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	23091	0.22
chr2_121266505_121266656	0.66	LINC01101	long intergenic non-protein coding RNA 1101	42883	0.19
chr5_65107256_65107407	0.66	NLN	neurolysin (metallopeptidase M3 family)	23141	0.22
chr3_119854481_119854726	0.65	ENSG00000244139	.	13847	0.18
chr8_23275057_23275208	0.64	LOXL2	lysyl oxidase-like 2	7672	0.19
chr2_36791072_36791223	0.64	AC007401.2	Uncharacterized protein	11736	0.19
chr2_28384161_28384312	0.64	AC093690.1		149090	0.04
chr9_101250638_101250789	0.64	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	220766	0.02
chr6_110008406_110008557	0.64	AK9	adenylate kinase 9	3228	0.27
chr4_102077826_102078189	0.63	ENSG00000221265	.	173564	0.03
chr16_29302364_29302928	0.63	RP11-231C14.6		21025	0.17
chr11_74398613_74398764	0.63	ENSG00000223202	.	2419	0.21
chr8_126667741_126667892	0.63	ENSG00000266452	.	211009	0.02
chr3_71651118_71651323	0.62	FOXP1	forkhead box P1	18080	0.2
chr15_70719035_70719186	0.62	ENSG00000200216	.	233535	0.02
chr22_36863560_36864238	0.62	TXN2	thioredoxin 2	13488	0.14
chr2_197200446_197200597	0.62	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	26425	0.19
chr2_238775076_238775227	0.62	ENSG00000263723	.	3396	0.24
chr18_28779535_28779686	0.61	DSC1	desmocollin 1	36791	0.15
chr2_182819845_182819996	0.61	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C	30631	0.17
chr11_45684848_45684999	0.61	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	2249	0.32
chr2_217290932_217291083	0.61	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	2492	0.24
chr3_185450101_185450459	0.61	C3orf65	chromosome 3 open reading frame 65	19200	0.2
chr12_11733022_11733284	0.61	ENSG00000251747	.	33740	0.16
chr5_14268406_14268609	0.60	TRIO	trio Rho guanine nucleotide exchange factor	22579	0.28
chr11_130595850_130596001	0.60	C11orf44	chromosome 11 open reading frame 44	53074	0.17
chr8_23654560_23654711	0.60	ENSG00000207027	.	9255	0.19
chr8_22602219_22602370	0.60	ENSG00000253125	.	2722	0.25
chr11_108908959_108909110	0.60	ENSG00000201243	.	32790	0.23
chr20_49982186_49982337	0.59	ENSG00000263645	.	11597	0.27
chr11_2934551_2934724	0.59	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense	9667	0.12
chr6_17981901_17982056	0.59	KIF13A	kinesin family member 13A	5716	0.3
chr8_18672049_18672314	0.58	ENSG00000251963	.	5045	0.25
chr6_41680801_41681561	0.58	RP11-298J23.5		6953	0.13
chr11_34366304_34366455	0.58	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2	12423	0.26
chr3_65941769_65941920	0.57	MAGI1-IT1	MAGI1 intronic transcript 1 (non-protein coding)	1611	0.39
chr13_110903096_110903247	0.57	COL4A2	collagen, type IV, alpha 2	54988	0.14
chr16_54111137_54111413	0.57	RP11-357N13.1		22780	0.19
chr2_20768919_20769070	0.57	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	23314	0.2
chr3_57094594_57094897	0.57	SPATA12	spermatogenesis associated 12	276	0.91
chr1_31229795_31230155	0.57	LAPTM5	lysosomal protein transmembrane 5	692	0.65
chr6_110538771_110539057	0.57	CDC40	cell division cycle 40	37290	0.17
chr10_29760583_29760940	0.57	SVIL	supervillin	24686	0.2
chr17_13447545_13447833	0.56	ENSG00000221698	.	726	0.71
chr22_37960029_37960180	0.56	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	309	0.83
chr9_84106067_84106472	0.56	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	122168	0.06
chr1_113007807_113007958	0.56	WNT2B	wingless-type MMTV integration site family, member 2B	1281	0.49
chr11_128733246_128733397	0.56	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	3855	0.23
chr3_45174222_45174373	0.56	CDCP1	CUB domain containing protein 1	13617	0.22
chr10_104364228_104364579	0.56	ENSG00000207029	.	13122	0.16
chr6_11771736_11771887	0.56	ADTRP	androgen-dependent TFPI-regulating protein	7225	0.29
chr1_218548529_218548680	0.56	TGFB2	transforming growth factor, beta 2	29027	0.19
chr18_421940_422183	0.55	RP11-720L2.2		2355	0.36
chr2_86019950_86020101	0.55	AC105053.3		22228	0.13
chr1_215277672_215277823	0.55	KCNK2	potassium channel, subfamily K, member 2	20887	0.3
chr1_207013289_207013440	0.55	IL19	interleukin 19	11142	0.16
chrX_48323593_48323869	0.55	SLC38A5	solute carrier family 38, member 5	2149	0.21
chr5_73839036_73839187	0.55	HEXB	hexosaminidase B (beta polypeptide)	96737	0.07
chr6_43978405_43978700	0.55	ENSG00000265518	.	2186	0.27
chr2_204357721_204357872	0.55	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2280	0.42
chr15_73988384_73988728	0.54	CD276	CD276 molecule	3425	0.28
chr2_20696028_20696179	0.54	ENSG00000200829	.	15498	0.21
chr12_6388900_6389082	0.54	PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	30611	0.12
chr5_171810242_171810393	0.54	SH3PXD2B	SH3 and PX domains 2B	32927	0.17
chr19_4377112_4377465	0.54	SH3GL1	SH3-domain GRB2-like 1	3001	0.11
chr13_99804178_99804329	0.54	UBAC2	UBA domain containing 2	48775	0.12
chr7_129536508_129536659	0.53	UBE2H	ubiquitin-conjugating enzyme E2H	54584	0.09
chr8_123193136_123193287	0.53	ENSG00000238901	.	490319	0.0
chr1_172321665_172322022	0.53	ENSG00000252354	.	4560	0.2
chr13_31393568_31393719	0.53	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	83998	0.08
chr6_113371549_113371725	0.53	ENSG00000201386	.	78942	0.12
chr9_79175718_79175869	0.53	ENSG00000241781	.	10938	0.26
chr21_39832528_39832820	0.53	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	37671	0.22
chr7_71334038_71334189	0.52	ENSG00000201014	.	44728	0.21
chr11_859519_859810	0.52	RP11-1391J7.1		131	0.9
chr20_10020938_10021230	0.52	SNAP25-AS1	SNAP25 antisense RNA 1	5112	0.21
chr8_59664911_59665062	0.52	ENSG00000201231	.	62125	0.13
chr8_81170320_81170792	0.52	ENSG00000265588	.	16932	0.2
chr1_31870163_31870721	0.52	SERINC2	serine incorporator 2	11970	0.15
chr6_17968495_17968754	0.52	KIF13A	kinesin family member 13A	19070	0.26
chr7_129650015_129650166	0.52	RP11-306G20.1		1396	0.32
chr8_143757384_143757535	0.52	PSCA	prostate stem cell antigen	4415	0.13
chr1_28765982_28766202	0.52	PHACTR4	phosphatase and actin regulator 4	1410	0.33
chr2_121487319_121487470	0.51	GLI2	GLI family zinc finger 2	6429	0.31
chr15_76236352_76236503	0.51	FBXO22	F-box protein 22	11286	0.19
chr13_110492530_110492868	0.51	IRS2	insulin receptor substrate 2	53784	0.15
chr3_23609408_23609644	0.51	ENSG00000252562	.	45724	0.16
chr22_27872802_27872953	0.51	RP11-375H17.1		239591	0.02
chr17_41613704_41613971	0.51	ETV4	ets variant 4	6035	0.15
chr2_25570321_25570568	0.51	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	4985	0.24
chr12_3277713_3277864	0.51	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	18825	0.21
chr12_132385199_132385350	0.51	ULK1	unc-51 like autophagy activating kinase 1	5761	0.18
chr19_35611938_35612089	0.51	FXYD3	FXYD domain containing ion transport regulator 3	1746	0.19
chr12_109089080_109089525	0.51	CORO1C	coronin, actin binding protein, 1C	876	0.54
chr4_74140546_74140697	0.50	ENSG00000221639	.	10944	0.19
chr2_153271980_153272131	0.50	FMNL2	formin-like 2	80304	0.11
chr1_206897327_206897801	0.50	ENSG00000199349	.	23873	0.13
chr12_56120404_56120555	0.50	CD63	CD63 molecule	364	0.7
chr21_33836630_33836895	0.50	EVA1C	eva-1 homolog C (C. elegans)	36120	0.13
chr7_137457647_137457798	0.50	DGKI	diacylglycerol kinase, iota	73560	0.12
chr4_10097090_10097875	0.50	ENSG00000264931	.	17166	0.14
chr8_132857612_132857763	0.50	EFR3A	EFR3 homolog A (S. cerevisiae)	58648	0.16
chr6_151358211_151358362	0.50	MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	176	0.94
chr17_40476887_40477238	0.50	STAT5A	signal transducer and activator of transcription 5A	18874	0.12
chr1_59943114_59943265	0.50	FGGY	FGGY carbohydrate kinase domain containing	76401	0.12
chr15_75954147_75954338	0.50	SNX33	sorting nexin 33	12145	0.09
chr14_75355002_75355210	0.50	DLST	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	6447	0.15
chr17_60780537_60780688	0.50	RP11-156L14.1		2955	0.22
chr1_156083605_156084089	0.50	LMNA	lamin A/C	614	0.59
chr18_43344332_43344486	0.49	RP11-116O18.3		17229	0.18
chr6_56514356_56514539	0.49	DST	dystonin	6653	0.32
chr11_67917649_67917930	0.49	CTD-2655K5.1		20524	0.14
chr4_182880871_182881022	0.49	ENSG00000251742	.	124685	0.06
chr7_135430284_135430435	0.49	FAM180A	family with sequence similarity 180, member A	3101	0.22
chr20_30198397_30198778	0.49	ENSG00000264395	.	3598	0.15
chr19_2503776_2503986	0.49	ENSG00000252962	.	742	0.61
chr6_100731277_100731428	0.49	RP1-121G13.2		143642	0.05
chr4_139819017_139819168	0.49	RP11-371F15.3		40043	0.17
chr17_47533894_47534339	0.49	NGFR	nerve growth factor receptor	38539	0.1
chr15_56201396_56201579	0.49	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	6365	0.26
chr20_30398171_30398354	0.49	MYLK2	myosin light chain kinase 2	8849	0.15
chr4_1331225_1331376	0.49	UVSSA	UV-stimulated scaffold protein A	9754	0.13
chr14_69506117_69506268	0.49	ACTN1-AS1	ACTN1 antisense RNA 1	59434	0.12
chr6_20877758_20877909	0.48	RP3-348I23.2		76908	0.12
chr13_96161803_96162207	0.48	CLDN10-AS1	CLDN10 antisense RNA 1	24159	0.21
chr19_45601288_45601848	0.48	PPP1R37	protein phosphatase 1, regulatory subunit 37	5136	0.1
chr4_95470032_95470452	0.48	PDLIM5	PDZ and LIM domain 5	25366	0.27
chr19_43239918_43240069	0.48	PSG3	pregnancy specific beta-1-glycoprotein 3	4636	0.24
chr20_19865364_19865598	0.48	RIN2	Ras and Rab interactor 2	1684	0.48
chr3_88857018_88857169	0.48	EPHA3	EPH receptor A3	299581	0.01
chr11_19944459_19944610	0.48	NAV2-AS3	NAV2 antisense RNA 3	58349	0.14
chr17_79392708_79392859	0.48	RP11-1055B8.7	BAH and coiled-coil domain-containing protein 1	12613	0.1
chr7_139138466_139138617	0.48	ENSG00000252332	.	5055	0.21
chr14_51403055_51403266	0.48	PYGL	phosphorylase, glycogen, liver	8014	0.19
chr5_77175661_77175812	0.48	TBCA	tubulin folding cofactor A	11132	0.3
chr3_168823031_168823291	0.47	MECOM	MDS1 and EVI1 complex locus	22661	0.28
chr7_55177396_55177547	0.47	EGFR	epidermal growth factor receptor	55	0.99
chr2_54998328_54998479	0.47	AC104781.1		22862	0.2
chr18_42749036_42749187	0.47	RP11-846C15.2		11968	0.26
chr2_38007244_38007545	0.47	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	41783	0.19
chr22_38624639_38624924	0.47	RP1-5O6.5		2545	0.16
chr20_11375066_11375217	0.47	C20orf187	chromosome 20 open reading frame 187	366330	0.01
chr10_12762810_12762961	0.47	ENSG00000221331	.	4467	0.33
chr14_95008607_95008758	0.47	SERPINA4	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	18746	0.14
chr2_225010855_225011006	0.47	ENSG00000211987	.	93343	0.08
chr11_65678995_65679525	0.47	C11orf68	chromosome 11 open reading frame 68	6571	0.08
chr2_9713569_9713720	0.47	ADAM17	ADAM metallopeptidase domain 17	17723	0.16
chr21_33896071_33896222	0.47	ENSG00000252045	.	14463	0.16
chr16_75297374_75297525	0.47	BCAR1	breast cancer anti-estrogen resistance 1	865	0.52
chr19_2028762_2028950	0.47	AC007136.1		2194	0.17
chr9_130326042_130326221	0.47	FAM129B	family with sequence similarity 129, member B	5236	0.19
chr3_170435229_170435380	0.47	RP11-373E16.3		60953	0.13
chr10_5631913_5632190	0.47	ENSG00000240577	.	41375	0.11
chr17_28848013_28848164	0.47	TBC1D29	TBC1 domain family, member 29	36042	0.12
chr11_60686848_60686999	0.47	TMEM109	transmembrane protein 109	227	0.84
chr17_46045289_46045440	0.47	CDK5RAP3	CDK5 regulatory subunit associated protein 3	188	0.88
chr19_38531152_38531303	0.47	ENSG00000221258	.	13378	0.17
chr7_1196429_1196848	0.47	ZFAND2A	zinc finger, AN1-type domain 2A	730	0.57
chr5_149265721_149265872	0.46	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	53218	0.1
chr9_124044825_124044976	0.46	RP11-477J21.6		108	0.95
chr14_105147313_105147511	0.46	ENSG00000265291	.	3326	0.17
chr1_209780440_209781046	0.46	LAMB3	laminin, beta 3	11400	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0018101	protein citrullination(GO:0018101)
0.2	0.7	GO:0070141	response to UV-A(GO:0070141)
0.2	0.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.8	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.3	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1	0.3	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.2	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1	0.5	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.7	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.1	0.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.2	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.1	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1	0.2	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.2	GO:0021508	floor plate formation(GO:0021508)
0.1	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.3	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.2	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.1	GO:0090030	regulation of glucocorticoid biosynthetic process(GO:0031946) regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.2	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.3	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.4	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.2	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1	0.5	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0060068	vagina development(GO:0060068)
0.0	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.2	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.2	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0042663	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.2	GO:0010224	response to UV-B(GO:0010224)
0.0	0.2	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.2	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.2	GO:0048641	regulation of skeletal muscle tissue development(GO:0048641)
0.0	0.2	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0045713	low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.2	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.3	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.3	GO:0090200	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.1	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.3	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0060039	pericardium development(GO:0060039)
0.0	0.2	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.0	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.3	GO:0030878	thyroid gland development(GO:0030878)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0071331	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0042635	positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.2	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	0.0	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0042754	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.4	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.1	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.0	GO:0032488	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.3	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.2	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.3	GO:0000272	polysaccharide catabolic process(GO:0000272)
0.0	0.1	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.1	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.3	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0003407	neural retina development(GO:0003407)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.2	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.0	GO:0070091	glucagon secretion(GO:0070091)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0019363	pyridine nucleotide biosynthetic process(GO:0019363)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0008207	C21-steroid hormone metabolic process(GO:0008207)
0.0	0.2	GO:0008272	sulfate transport(GO:0008272)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.0	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.0	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.8	GO:0007565	female pregnancy(GO:0007565)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.0	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0034763	negative regulation of transmembrane transport(GO:0034763) negative regulation of ion transmembrane transport(GO:0034766)
0.0	0.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:0006565	L-serine catabolic process(GO:0006565)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0051154	negative regulation of striated muscle cell differentiation(GO:0051154)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.6	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.3	GO:0042599	lamellar body(GO:0042599)
0.1	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.4	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.8	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:1902562	H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.3	GO:0030018	Z disc(GO:0030018)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.2	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.4	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.3	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.3	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0	0.0	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.7	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.0	ST ADRENERGIC	Adrenergic Pathway
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	Genes involved in Class I MHC mediated antigen processing & presentation
0.0	0.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins