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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for FOXA1

Z-value: 2.87

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Transcription factors associated with FOXA1

Gene Symbol	Gene ID	Gene Info
FOXA1 Ensembl NCBI GeneCards UniProt	ENSG00000129514.4	forkhead box A1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_38020205_38020356	FOXA1	43959	0.158974	0.69	4.0e-02	Click!
chr14_38067124_38067275	FOXA1	2046	0.319251	-0.55	1.3e-01	Click!
chr14_38068230_38068468	FOXA1	896	0.625853	-0.52	1.5e-01	Click!
chr14_38069963_38070114	FOXA1	793	0.685836	-0.52	1.6e-01	Click!
chr14_38068026_38068177	FOXA1	1144	0.527334	-0.50	1.7e-01	Click!

Activity of the FOXA1 motif across conditions

Conditions sorted by the z-value of the FOXA1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_52123824_52124076	1.38	LINC00696	long intergenic non-protein coding RNA 696	26383	0.11
chr17_13492868_13493127	1.29	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	12247	0.25
chr1_226456896_226457047	1.20	ENSG00000238545	.	34992	0.12
chr3_149738282_149738433	1.15	PFN2	profilin 2	2241	0.29
chr2_1735109_1735435	1.14	PXDN	peroxidasin homolog (Drosophila)	12942	0.27
chr1_162319832_162320115	1.12	ENSG00000207729	.	7637	0.11
chr1_12483776_12483927	1.11	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	13927	0.23
chr12_66089003_66089154	1.11	HMGA2	high mobility group AT-hook 2	128833	0.05
chr13_33837466_33837749	1.11	ENSG00000236581	.	7909	0.23
chr6_170713641_170713792	1.10	RP1-140C12.2		9511	0.24
chr6_44026555_44026902	1.07	RP5-1120P11.1		15661	0.16
chr3_149058191_149058568	1.05	TM4SF18	transmembrane 4 L six family member 18	6178	0.2
chr13_33701246_33701542	1.04	STARD13-IT1	STARD13 intronic transcript 1 (non-protein coding)	37152	0.17
chr3_149865425_149865655	1.02	RP11-167H9.4		49721	0.15
chr3_47155939_47156090	1.02	ENSG00000251938	.	25916	0.16
chr1_88109761_88109982	1.02	ENSG00000199318	.	190815	0.03
chr5_37739048_37739199	1.02	ENSG00000206743	.	38584	0.18
chr3_111623515_111623944	1.02	PHLDB2	pleckstrin homology-like domain, family B, member 2	6728	0.26
chr1_162648145_162648296	1.01	DDR2	discoidin domain receptor tyrosine kinase 2	45960	0.14
chr20_49440990_49441141	1.00	BCAS4	breast carcinoma amplified sequence 4	29458	0.14
chr11_11048560_11048711	1.00	ZBED5-AS1	ZBED5 antisense RNA 1	161827	0.03
chr9_124942129_124942280	0.99	MORN5	MORN repeat containing 5	15310	0.14
chr14_101308246_101309004	0.98	ENSG00000214548	.	7020	0.04
chr20_4572876_4573386	0.96	PRNP	prion protein	93751	0.08
chr5_77887462_77888069	0.96	LHFPL2	lipoma HMGIC fusion partner-like 2	42791	0.21
chr3_29388301_29388452	0.95	ENSG00000216169	.	22536	0.22
chr13_76357871_76358022	0.95	LMO7	LIM domain 7	5028	0.29
chr6_11206787_11207012	0.95	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	25992	0.18
chr10_17010138_17010335	0.94	CUBN	cubilin (intrinsic factor-cobalamin receptor)	15958	0.27
chr7_1196429_1196848	0.93	ZFAND2A	zinc finger, AN1-type domain 2A	730	0.57
chr6_17418790_17419045	0.93	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	24974	0.25
chr6_53847267_53847418	0.93	MLIP-IT1	MLIP intronic transcript 1 (non-protein coding)	16346	0.2
chr4_54054772_54054923	0.93	ENSG00000207385	.	76887	0.11
chr2_10112743_10112894	0.93	GRHL1	grainyhead-like 1 (Drosophila)	20991	0.16
chr21_36589845_36589996	0.93	RUNX1	runt-related transcription factor 1	168279	0.04
chr10_91314258_91314409	0.92	SLC16A12	solute carrier family 16, member 12	2065	0.33
chr2_101383004_101383236	0.92	NPAS2	neuronal PAS domain protein 2	53494	0.13
chr1_25155741_25155892	0.92	ENSG00000238482	.	51346	0.13
chr12_2397196_2397863	0.91	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	18587	0.24
chr2_9388682_9388833	0.90	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	41863	0.19
chr9_111631485_111631636	0.90	ACTL7A	actin-like 7A	6957	0.2
chr1_234688974_234689202	0.90	ENSG00000212144	.	39933	0.14
chr9_14272920_14273071	0.89	NFIB	nuclear factor I/B	35017	0.2
chr11_92029234_92029385	0.89	FAT3	FAT atypical cadherin 3	55953	0.17
chr9_97676062_97676213	0.89	RP11-49O14.2		13426	0.18
chr5_73497876_73498136	0.89	ENSG00000222551	.	69584	0.13
chr7_83306990_83307141	0.89	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	28739	0.27
chr1_92317043_92317194	0.88	TGFBR3	transforming growth factor, beta receptor III	10032	0.22
chr21_27762100_27762398	0.88	AP001596.6		206	0.95
chr6_43092451_43092602	0.87	PTK7	protein tyrosine kinase 7	5803	0.13
chr7_65747824_65747975	0.86	TPST1	tyrosylprotein sulfotransferase 1	61308	0.1
chr2_151334722_151334873	0.86	RND3	Rho family GTPase 3	7099	0.34
chr3_123376529_123376680	0.86	MYLK-AS2	MYLK antisense RNA 2	31887	0.15
chr20_56592416_56592650	0.85	ENSG00000221451	.	41459	0.15
chr5_37771237_37771562	0.85	ENSG00000238335	.	30768	0.2
chr12_96028962_96029113	0.85	ENSG00000212448	.	17572	0.22
chr2_47077448_47077599	0.85	AC016722.3		3112	0.21
chr4_54554159_54554310	0.85	RP11-317M11.1		7834	0.23
chr11_8750398_8750549	0.85	ST5	suppression of tumorigenicity 5	2752	0.19
chr4_177706098_177706386	0.85	VEGFC	vascular endothelial growth factor C	7639	0.32
chr2_40630418_40630569	0.85	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	26927	0.26
chr21_40330803_40331008	0.85	ENSG00000272015	.	64196	0.13
chr12_88207310_88207461	0.84	C12orf50	chromosome 12 open reading frame 50	214355	0.02
chr5_119945077_119945228	0.84	PRR16	proline rich 16	7631	0.32
chr21_44752301_44752505	0.84	SIK1	salt-inducible kinase 1	94605	0.08
chr20_10073825_10073976	0.84	ENSG00000264599	.	36932	0.17
chr12_2289332_2289483	0.84	CACNA1C-AS4	CACNA1C antisense RNA 4	43238	0.16
chr6_52380007_52380403	0.83	TRAM2	translocation associated membrane protein 2	61508	0.12
chr1_201714078_201714229	0.83	NAV1	neuron navigator 1	5157	0.14
chr1_170644226_170644377	0.83	PRRX1	paired related homeobox 1	11223	0.29
chr2_66723693_66723844	0.83	MEIS1	Meis homeobox 1	12291	0.22
chr6_127042369_127042728	0.82	ENSG00000201613	.	131009	0.06
chr7_134575677_134575828	0.82	CALD1	caldesmon 1	399	0.91
chr12_56920851_56921002	0.82	RBMS2	RNA binding motif, single stranded interacting protein 2	5143	0.15
chr8_1905992_1906143	0.82	KBTBD11	kelch repeat and BTB (POZ) domain containing 11	15977	0.25
chr13_115064652_115064803	0.82	CHAMP1	chromosome alignment maintaining phosphoprotein 1	15261	0.15
chr9_18481044_18481195	0.81	ADAMTSL1	ADAMTS-like 1	6888	0.31
chr14_59680322_59680595	0.81	DAAM1	dishevelled associated activator of morphogenesis 1	25041	0.26
chr6_8084010_8084161	0.81	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	13459	0.22
chr21_35705528_35705679	0.81	ENSG00000266007	.	28173	0.13
chr7_137222625_137222776	0.81	PTN	pleiotrophin	194089	0.03
chr11_91714922_91715073	0.81	FAT3	FAT atypical cadherin 3	370265	0.01
chr6_157639005_157639490	0.81	ENSG00000252609	.	73184	0.11
chr3_187485722_187485873	0.80	BCL6	B-cell CLL/lymphoma 6	22282	0.21
chr18_53813766_53813917	0.80	ENSG00000201816	.	67016	0.15
chr6_125335196_125335438	0.80	RNF217	ring finger protein 217	30803	0.21
chr17_76371674_76372066	0.80	PGS1	phosphatidylglycerophosphate synthase 1	2851	0.19
chr12_124864748_124865018	0.80	NCOR2	nuclear receptor corepressor 2	8487	0.28
chr2_217429120_217429271	0.79	AC073321.3		42466	0.12
chr11_65042904_65043175	0.79	POLA2	polymerase (DNA directed), alpha 2, accessory subunit	6939	0.14
chr4_187857949_187858100	0.79	ENSG00000252382	.	79414	0.12
chr12_89764903_89765288	0.79	DUSP6	dual specificity phosphatase 6	18047	0.24
chr8_93033119_93033344	0.79	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	1828	0.47
chr11_112172866_112173215	0.79	PLET1	placenta expressed transcript 1	41457	0.1
chr8_131685378_131685529	0.79	RP11-737F9.2		219578	0.02
chr20_4494153_4494304	0.78	PRNP	prion protein	172654	0.03
chr19_31714700_31714851	0.78	AC020952.1	Uncharacterized protein	74413	0.12
chr3_55363268_55363419	0.78	WNT5A	wingless-type MMTV integration site family, member 5A	151881	0.04
chr5_59791940_59792091	0.78	PDE4D	phosphodiesterase 4D, cAMP-specific	8112	0.29
chr9_133658643_133658794	0.78	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	51735	0.13
chr2_9476964_9477115	0.78	ITGB1BP1	integrin beta 1 binding protein 1	83384	0.08
chr1_235034792_235034943	0.78	ENSG00000239690	.	5066	0.29
chr3_149796389_149796540	0.78	ENSG00000243321	.	846	0.62
chr1_244512198_244512349	0.77	C1orf100	chromosome 1 open reading frame 100	3664	0.3
chr21_43476556_43476707	0.77	UMODL1	uromodulin-like 1	6437	0.21
chr1_24593508_24593659	0.77	ENSG00000266511	.	12762	0.16
chr1_210551647_210551798	0.77	ENSG00000200972	.	4111	0.28
chr22_43123432_43123745	0.77	A4GALT	alpha 1,4-galactosyltransferase	31949	0.13
chr8_38255858_38256009	0.77	LETM2	leucine zipper-EF-hand containing transmembrane protein 2	1442	0.28
chr12_89969123_89969521	0.77	RP11-981P6.1		14416	0.14
chr5_136901296_136901447	0.76	ENSG00000221612	.	32228	0.19
chr7_30945737_30945888	0.76	AQP1	aquaporin 1 (Colton blood group)	5658	0.26
chr17_64499157_64499308	0.76	RP11-4F22.2		86260	0.08
chr22_30648620_30649241	0.76	LIF	leukemia inhibitory factor	6090	0.11
chr13_27159400_27159551	0.76	WASF3	WAS protein family, member 3	27588	0.22
chr20_10640959_10641110	0.76	JAG1	jagged 1	2120	0.39
chr13_76405420_76405571	0.76	LMO7	LIM domain 7	1726	0.42
chr18_19611830_19611981	0.75	ENSG00000265568	.	32375	0.16
chr3_161632466_161632617	0.75	OTOL1	otolin 1	417945	0.01
chr1_21301357_21301508	0.75	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1903	0.38
chr11_87911794_87912092	0.75	ENSG00000266581	.	2273	0.31
chr7_17408913_17409156	0.75	ENSG00000199473	.	3916	0.32
chr18_57332925_57333076	0.75	CCBE1	collagen and calcium binding EGF domains 1	394	0.86
chr22_40906008_40906449	0.74	RP4-591N18.2		11576	0.17
chr18_8141122_8141273	0.74	RP11-376P6.3		13359	0.22
chr1_170556829_170556980	0.74	RP11-576I22.2		55116	0.13
chr3_32002663_32002814	0.74	OSBPL10	oxysterol binding protein-like 10	20054	0.19
chr7_42105852_42106003	0.74	GLI3	GLI family zinc finger 3	161393	0.04
chrX_45712894_45713045	0.74	ENSG00000212347	.	39445	0.2
chr8_89969634_89969785	0.74	RP11-586K2.1		257189	0.02
chr1_200142035_200142186	0.73	ENSG00000221403	.	28148	0.23
chr12_57845396_57845698	0.73	INHBE	inhibin, beta E	2939	0.12
chr2_65597769_65598332	0.73	SPRED2	sprouty-related, EVH1 domain containing 2	4266	0.26
chr14_68408657_68408808	0.73	RAD51B	RAD51 paralog B	118471	0.05
chr9_110160402_110160553	0.73	ENSG00000263459	.	35413	0.19
chr15_63389887_63390105	0.73	LACTB	lactamase, beta	24003	0.14
chr10_73857296_73857447	0.73	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	8581	0.23
chr22_19275085_19275350	0.73	CLTCL1	clathrin, heavy chain-like 1	3991	0.21
chr8_28273198_28273349	0.73	ENSG00000207361	.	692	0.58
chr15_77695471_77695629	0.73	PEAK1	pseudopodium-enriched atypical kinase 1	16892	0.22
chr19_15360381_15360741	0.72	EPHX3	epoxide hydrolase 3	16315	0.15
chr4_78092741_78092892	0.72	CCNG2	cyclin G2	13237	0.22
chr12_7695771_7696015	0.72	CD163	CD163 molecule	39404	0.15
chr5_168724075_168724226	0.72	SLIT3	slit homolog 3 (Drosophila)	3563	0.32
chr12_80950304_80950455	0.72	RP11-272K23.3		37101	0.19
chr11_131615096_131615385	0.72	NTM	neurotrimin	84352	0.1
chr3_157878406_157878557	0.72	RSRC1	arginine/serine-rich coiled-coil 1	42380	0.18
chr1_68218070_68218221	0.72	ENSG00000238778	.	20191	0.2
chr6_166985772_166986271	0.72	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	27843	0.18
chr2_38408174_38408471	0.72	ENSG00000199603	.	33765	0.18
chr5_95197946_95198168	0.72	ENSG00000250362	.	567	0.69
chr8_93151229_93151380	0.71	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	35790	0.24
chr22_28641976_28642127	0.71	ENSG00000201209	.	13240	0.26
chr2_133607064_133607215	0.71	AC016909.1		65991	0.14
chr2_216372275_216372914	0.71	AC012462.1		71618	0.11
chr8_99191274_99191425	0.71	ENSG00000252558	.	13192	0.2
chr2_145823231_145823382	0.71	ENSG00000253036	.	269332	0.02
chr9_115947226_115947377	0.71	SLC31A2	solute carrier family 31 (copper transporter), member 2	34079	0.13
chr12_13025413_13025645	0.70	GPRC5A	G protein-coupled receptor, family C, group 5, member A	18187	0.14
chr21_32591799_32591950	0.70	TIAM1	T-cell lymphoma invasion and metastasis 1	57209	0.16
chr3_149015625_149015955	0.70	RP11-206M11.7		13221	0.19
chr15_63142711_63142998	0.70	RP11-1069G10.1		6074	0.22
chr5_14178416_14178612	0.70	TRIO	trio Rho guanine nucleotide exchange factor	5393	0.35
chr2_192128890_192129041	0.70	MYO1B	myosin IB	666	0.8
chr15_77437829_77437980	0.70	TSPAN3	tetraspanin 3	61578	0.12
chr16_70779927_70780078	0.69	RP11-394B2.6		958	0.42
chr9_6564725_6564876	0.69	ENSG00000252110	.	1625	0.4
chr20_13010280_13010431	0.69	SPTLC3	serine palmitoyltransferase, long chain base subunit 3	20358	0.28
chr9_18493407_18493558	0.69	ADAMTSL1	ADAMTS-like 1	19251	0.26
chr8_98102165_98102316	0.69	KB-1958F4.2		43367	0.16
chr15_40384302_40384677	0.69	RP11-521C20.3		3456	0.2
chr3_71153764_71153915	0.69	FOXP1	forkhead box P1	25905	0.27
chr10_100134830_100134981	0.68	ENSG00000221419	.	20159	0.18
chr2_37699621_37699772	0.68	ENSG00000253078	.	36945	0.18
chr13_109567579_109568598	0.68	MYO16	myosin XVI	29571	0.26
chr6_155593827_155593978	0.68	CLDN20	claudin 20	8755	0.2
chr1_161235969_161236120	0.68	PCP4L1	Purkinje cell protein 4 like 1	7527	0.09
chr14_79416720_79416871	0.68	CTD-2243E23.1		124310	0.06
chr8_141001651_141001976	0.68	C8orf17	chromosome 8 open reading frame 17	58397	0.15
chr2_144842252_144842403	0.68	AC016910.1		147687	0.04
chr11_86651165_86651376	0.68	FZD4	frizzled family receptor 4	15163	0.22
chr18_12336971_12337122	0.67	TUBB6	tubulin, beta 6 class V	26080	0.14
chr15_85888485_85888636	0.67	AKAP13	A kinase (PRKA) anchor protein 13	35258	0.15
chr3_25518094_25518245	0.67	RARB	retinoic acid receptor, beta	18368	0.25
chr4_119744605_119744756	0.67	SEC24D	SEC24 family member D	12613	0.26
chr1_30161111_30161262	0.67	ENSG00000221126	.	43661	0.21
chr9_116336420_116336661	0.67	RGS3	regulator of G-protein signaling 3	6400	0.23
chr4_14061132_14061426	0.67	ENSG00000252092	.	401028	0.01
chr15_29963760_29963911	0.67	RP11-680F8.1		3359	0.27
chr1_200340980_200341213	0.67	ZNF281	zinc finger protein 281	38024	0.22
chr3_194286532_194286683	0.67	TMEM44-AS1	TMEM44 antisense RNA 1	18133	0.13
chr18_12598337_12598791	0.67	SPIRE1	spire-type actin nucleation factor 1	54520	0.09
chr1_68663652_68663803	0.67	ENSG00000221203	.	14434	0.21
chr6_136934256_136934407	0.66	RP3-325F22.3		15979	0.16
chr17_19167294_19167445	0.66	EPN2	epsin 2	6136	0.13
chr6_144327355_144327506	0.66	PLAGL1	pleiomorphic adenoma gene-like 1	1968	0.44
chr2_151336761_151336912	0.66	RND3	Rho family GTPase 3	5060	0.36
chr18_60153206_60153357	0.66	ZCCHC2	zinc finger, CCHC domain containing 2	36959	0.19
chr15_90541462_90541613	0.66	ZNF710	zinc finger protein 710	3087	0.2
chr3_98642134_98642285	0.66	ENSG00000207331	.	14906	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	0.5	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2	0.5	GO:0007144	female meiosis I(GO:0007144)
0.2	0.5	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.2	0.5	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.5	GO:0045056	transcytosis(GO:0045056)
0.1	0.1	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.8	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.3	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.4	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.3	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.3	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1	0.3	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.2	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.4	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.4	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.3	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.8	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.5	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.8	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.5	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.1	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.4	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.3	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.2	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.1	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.2	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.4	GO:0009629	response to gravity(GO:0009629)
0.1	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.3	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.1	0.3	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.7	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0048263	determination of dorsal identity(GO:0048263)
0.0	0.2	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.4	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.3	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0021843	substrate-independent telencephalic tangential migration(GO:0021826) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0061213	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.3	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.4	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.2	GO:0061377	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0	0.0	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0	0.2	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.3	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.4	GO:0098764	meiosis I cell cycle phase(GO:0098764)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.2	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.2	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.4	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.2	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.5	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.0	0.1	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0006949	syncytium formation(GO:0006949)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:0007619	courtship behavior(GO:0007619)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.3	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.0	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.3	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.3	GO:0019079	viral genome replication(GO:0019079)
0.0	0.1	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.9	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.0	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0042441	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.0	GO:0060433	bronchus development(GO:0060433)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0071398	cellular response to fatty acid(GO:0071398)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.0	GO:0003170	heart valve development(GO:0003170) atrioventricular valve development(GO:0003171) heart valve morphogenesis(GO:0003179) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.0	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0018995	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.3	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0032449	CBM complex(GO:0032449)
0.1	0.5	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.6	GO:0008091	spectrin(GO:0008091)
0.1	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.5	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.7	GO:0005811	lipid particle(GO:0005811)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	1.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.6	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	3.0	GO:0030016	myofibril(GO:0030016)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.7	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.0	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0030990	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	3.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0030027	lamellipodium(GO:0030027)
0.0	1.8	GO:0015629	actin cytoskeleton(GO:0015629)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0045545	syndecan binding(GO:0045545)
0.1	0.4	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.6	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.8	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.5	GO:0017166	vinculin binding(GO:0017166)
0.1	0.3	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	0.6	GO:0005112	Notch binding(GO:0005112)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.2	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.2	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.3	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.8	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0005372	water transmembrane transporter activity(GO:0005372)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	1.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.0	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.0	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.0	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.0	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.0	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	ST ADRENERGIC	Adrenergic Pathway
0.1	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.8	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	3.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.8	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.4	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters

Results for FOXA1

Z-value: 2.87

Motif logo

Transcription factors associated with FOXA1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXA1 motif across conditions

Conditions sorted by the z-value of the FOXA1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: