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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.80

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol	Gene ID	Gene Info
FOXD1 Ensembl NCBI GeneCards UniProt	ENSG00000251493.2	forkhead box D1
FOXO1 Ensembl NCBI GeneCards UniProt	ENSG00000150907.6	forkhead box O1
FOXO6 Ensembl NCBI GeneCards UniProt	ENSG00000204060.4	forkhead box O6
FOXG1 Ensembl NCBI GeneCards UniProt	ENSG00000176165.7	forkhead box G1
FOXP1 Ensembl NCBI GeneCards UniProt	ENSG00000114861.14	forkhead box P1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_72676835_72676986	FOXD1	67442	0.108864	0.92	4.3e-04	Click!
chr5_72682570_72682721	FOXD1	61707	0.118698	0.83	6.0e-03	Click!
chr5_72661006_72661157	FOXD1	83271	0.085783	-0.82	7.0e-03	Click!
chr5_72662200_72662351	FOXD1	82077	0.087325	-0.77	1.4e-02	Click!
chr5_72659852_72660019	FOXD1	84417	0.084331	-0.75	2.1e-02	Click!
chr14_29234908_29235202	FOXG1	5	0.915966	0.50	1.7e-01	Click!
chr14_29235364_29235610	FOXG1	437	0.689545	0.26	5.0e-01	Click!
chr14_29235899_29236050	FOXG1	313	0.834414	-0.16	6.8e-01	Click!
chr14_29236236_29236387	FOXG1	24	0.965660	0.09	8.2e-01	Click!
chr13_41214731_41214882	FOXO1	25928	0.208413	0.97	1.6e-05	Click!
chr13_41178815_41178966	FOXO1	61844	0.118044	0.95	6.9e-05	Click!
chr13_41220604_41220755	FOXO1	20055	0.222068	0.92	4.0e-04	Click!
chr13_41191011_41191162	FOXO1	49648	0.146335	0.92	4.7e-04	Click!
chr13_41180871_41181022	FOXO1	59788	0.122494	0.91	6.4e-04	Click!
chr1_41828111_41828331	FOXO6	627	0.760722	0.81	7.8e-03	Click!
chr1_41832819_41833062	FOXO6	5346	0.231810	0.74	2.2e-02	Click!
chr1_41828523_41828674	FOXO6	1004	0.590308	0.64	6.5e-02	Click!
chr1_41809704_41809855	FOXO6	17815	0.208373	-0.59	9.7e-02	Click!
chr1_41810525_41810676	FOXO6	16994	0.209737	0.54	1.3e-01	Click!
chr3_71408104_71408255	FOXP1	54268	0.153246	0.96	5.1e-05	Click!
chr3_71407741_71407893	FOXP1	53906	0.154091	0.95	1.1e-04	Click!
chr3_71088545_71088921	FOXP1	25344	0.265743	0.93	2.5e-04	Click!
chr3_71205873_71206024	FOXP1	25960	0.261817	0.90	9.0e-04	Click!
chr3_71201588_71201739	FOXP1	21675	0.275991	0.89	1.2e-03	Click!

Activity of the FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif across conditions

Conditions sorted by the z-value of the FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_37564990_37565229	1.67	RP1-151B14.6		2312	0.19
chr22_37565362_37565513	0.89	RP1-151B14.6		2640	0.17
chr14_99676703_99676899	0.58	AL162151.4		52048	0.13
chr6_112159911_112160062	0.46	FYN	FYN oncogene related to SRC, FGR, YES	6161	0.3
chr3_59434943_59435235	0.38	C3orf67	chromosome 3 open reading frame 67	399279	0.01
chr10_6013068_6013219	0.37	IL15RA	interleukin 15 receptor, alpha	4841	0.17
chr20_4850289_4850440	0.35	ENSG00000252096	.	734	0.64
chr10_73866244_73866447	0.33	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	17555	0.2
chr1_117352879_117353040	0.32	CD2	CD2 molecule	55870	0.12
chr15_60841099_60841376	0.30	CTD-2501E16.2		19065	0.18
chr12_94144935_94145086	0.30	RP11-887P2.5		13411	0.22
chr10_63809015_63809493	0.30	ARID5B	AT rich interactive domain 5B (MRF1-like)	284	0.94
chr5_141505684_141505835	0.29	NDFIP1	Nedd4 family interacting protein 1	17689	0.23
chr1_101396601_101396752	0.29	SLC30A7	solute carrier family 30 (zinc transporter), member 7	30708	0.13
chr1_117350633_117350815	0.28	CD2	CD2 molecule	53635	0.12
chr17_60004372_60004770	0.28	INTS2	integrator complex subunit 2	216	0.94
chr14_61803214_61803450	0.28	PRKCH	protein kinase C, eta	7628	0.21
chr1_108620088_108620978	0.28	ENSG00000264753	.	59140	0.13
chr3_60047355_60047572	0.27	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	89880	0.11
chr4_3196032_3196318	0.27	HTT	huntingtin	34086	0.17
chr5_156630584_156630798	0.27	CTB-4E7.1		20699	0.11
chr1_207497311_207497658	0.27	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	2348	0.4
chr6_159276942_159277117	0.27	C6orf99	chromosome 6 open reading frame 99	13942	0.17
chr3_195280178_195280329	0.26	AC091633.3		6834	0.16
chr19_15441932_15442146	0.26	BRD4	bromodomain containing 4	678	0.67
chr1_25887348_25887770	0.26	LDLRAP1	low density lipoprotein receptor adaptor protein 1	17488	0.19
chr11_44702466_44702617	0.26	TSPAN18	tetraspanin 18	45474	0.15
chr15_60681725_60682013	0.26	ANXA2	annexin A2	1457	0.53
chr6_91168973_91169124	0.25	ENSG00000252676	.	12557	0.28
chr2_109225621_109225839	0.25	LIMS1	LIM and senescent cell antigen-like domains 1	2113	0.38
chr13_79768933_79769084	0.25	RBM26	RNA binding motif protein 26	146339	0.05
chr1_39026144_39026517	0.25	ENSG00000200796	.	163999	0.03
chr8_18070863_18071014	0.24	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)	1207	0.61
chr2_198712818_198712969	0.24	PLCL1	phospholipase C-like 1	37911	0.18
chr4_16125042_16125292	0.24	PROM1	prominin 1	39166	0.15
chr5_130622053_130622245	0.24	CDC42SE2	CDC42 small effector 2	22356	0.26
chr16_82686424_82686713	0.24	CDH13	cadherin 13	25870	0.24
chr19_44257251_44257558	0.24	SMG9	SMG9 nonsense mediated mRNA decay factor	1346	0.32
chrX_48457426_48457577	0.24	WDR13	WD repeat domain 13	1621	0.24
chr1_198658364_198658653	0.24	RP11-553K8.5		22318	0.23
chr13_41930416_41930674	0.24	ENSG00000223280	.	1750	0.37
chr17_4078692_4078901	0.24	ENSG00000251812	.	10825	0.11
chr10_6615495_6615646	0.24	PRKCQ	protein kinase C, theta	6631	0.33
chr22_20919404_20919765	0.23	MED15	mediator complex subunit 15	14007	0.14
chr2_204812325_204812548	0.23	ICOS	inducible T-cell co-stimulator	10933	0.28
chr13_41181146_41181443	0.23	FOXO1	forkhead box O1	59440	0.12
chr2_61194054_61194261	0.23	ENSG00000222251	.	31730	0.14
chr10_22981760_22981911	0.23	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	21202	0.26
chr10_80814068_80814219	0.23	ZMIZ1-AS1	ZMIZ1 antisense RNA 1	13082	0.24
chr12_120451943_120452094	0.23	CCDC64	coiled-coil domain containing 64	24345	0.17
chr13_99704509_99704704	0.23	ENSG00000207298	.	27118	0.17
chr16_4422995_4423273	0.23	VASN	vasorin	1285	0.32
chr1_65341937_65342174	0.23	JAK1	Janus kinase 1	90132	0.08
chr10_6216160_6216311	0.23	ENSG00000263628	.	22076	0.13
chr11_1536418_1536569	0.23	MOB2	MOB kinase activator 2	28517	0.12
chr10_33408293_33408482	0.23	ENSG00000263576	.	20823	0.22
chr17_8644282_8644450	0.23	CCDC42	coiled-coil domain containing 42	3739	0.23
chrX_131119863_131120181	0.22	ENSG00000265686	.	10851	0.22
chr3_46422581_46422760	0.22	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	8509	0.15
chr20_3781968_3782119	0.22	CDC25B	cell division cycle 25B	4965	0.13
chr9_117480861_117481126	0.22	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15	73395	0.09
chr14_100559253_100559404	0.22	EVL	Enah/Vasp-like	3956	0.16
chr1_117296640_117296969	0.22	CD2	CD2 molecule	203	0.95
chr17_71583944_71584095	0.22	RP11-277J6.2		53146	0.12
chr1_154316903_154317054	0.22	ENSG00000238365	.	5759	0.11
chr16_89453069_89453220	0.22	RP1-168P16.2		25828	0.12
chr18_9142468_9142619	0.22	ANKRD12	ankyrin repeat domain 12	4982	0.18
chr10_120458675_120458868	0.22	CACUL1	CDK2-associated, cullin domain 1	55987	0.12
chr1_112143570_112143721	0.22	RAP1A	RAP1A, member of RAS oncogene family	18754	0.16
chr3_51712516_51712741	0.21	TEX264	testis expressed 264	6717	0.16
chr16_22250202_22250429	0.21	EEF2K	eukaryotic elongation factor-2 kinase	32712	0.13
chr16_27457921_27458113	0.21	IL21R-AS1	IL21R antisense RNA 1	6697	0.2
chr8_41324261_41324428	0.21	GOLGA7	golgin A7	23571	0.16
chr1_42133532_42133769	0.21	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	33022	0.21
chr1_175156305_175156626	0.21	KIAA0040	KIAA0040	5425	0.29
chr5_14704726_14704885	0.21	FAM105B	family with sequence similarity 105, member B	23146	0.19
chr20_5826585_5826792	0.21	ENSG00000202380	.	44013	0.14
chr19_30167585_30167806	0.21	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	9914	0.23
chr7_44751743_44751894	0.21	ZMIZ2	zinc finger, MIZ-type containing 2	36362	0.14
chr14_64662084_64662484	0.21	SYNE2	spectrin repeat containing, nuclear envelope 2	6627	0.26
chr1_24833869_24834165	0.21	RCAN3	RCAN family member 3	40	0.97
chr22_23479491_23479838	0.21	ENSG00000221069	.	857	0.41
chr5_122879495_122879646	0.20	CSNK1G3	casein kinase 1, gamma 3	1539	0.49
chr1_206910364_206910608	0.20	ENSG00000199349	.	10951	0.16
chr6_49430346_49430584	0.20	MUT	methylmalonyl CoA mutase	439	0.59
chr7_142420927_142421220	0.20	PRSS1	protease, serine, 1 (trypsin 1)	36246	0.15
chr14_98341769_98341920	0.20	C14orf64	chromosome 14 open reading frame 64	102539	0.08
chr1_160398823_160399143	0.20	VANGL2	VANGL planar cell polarity protein 2	28607	0.11
chr2_11092825_11092976	0.20	KCNF1	potassium voltage-gated channel, subfamily F, member 1	40837	0.17
chr10_22178362_22178513	0.20	ENSG00000201364	.	43635	0.18
chr3_176863148_176863358	0.20	ENSG00000200882	.	19345	0.2
chrX_19858890_19859041	0.20	SH3KBP1	SH3-domain kinase binding protein 1	41096	0.19
chr6_167456374_167456589	0.20	FGFR1OP	FGFR1 oncogene partner	43585	0.11
chr16_1610753_1610904	0.20	LA16c-425C2.1		19481	0.08
chr3_66355046_66355262	0.20	ENSG00000206759	.	11510	0.22
chr19_45667322_45667563	0.20	NKPD1	NTPase, KAP family P-loop domain containing 1	4034	0.12
chr12_80327026_80327185	0.20	PPP1R12A	protein phosphatase 1, regulatory subunit 12A	1390	0.36
chr1_43419507_43419668	0.20	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	4913	0.21
chr10_90762525_90762763	0.20	ACTA2	actin, alpha 2, smooth muscle, aorta	11497	0.14
chr22_42636430_42636581	0.20	TCF20	transcription factor 20 (AR1)	25057	0.17
chr6_14785385_14785536	0.20	ENSG00000206960	.	138694	0.05
chr12_14583713_14583864	0.20	ATF7IP	activating transcription factor 7 interacting protein	7093	0.25
chr5_169700107_169700517	0.20	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	5981	0.24
chr15_62350389_62350636	0.20	VPS13C	vacuolar protein sorting 13 homolog C (S. cerevisiae)	2135	0.26
chr20_55975594_55975873	0.20	RP4-800J21.3		7615	0.16
chr9_46978785_46979071	0.20	RP11-111F5.5		234751	0.02
chr6_143111835_143111986	0.20	RP1-67K17.3		42330	0.17
chr5_34930527_34930913	0.20	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	1022	0.5
chr12_104296222_104296713	0.19	HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	27418	0.12
chr4_40235715_40235866	0.19	RHOH	ras homolog family member H	33826	0.17
chr5_134240040_134240274	0.19	PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	439	0.8
chr3_43334090_43334357	0.19	SNRK	SNF related kinase	6145	0.2
chr2_242048449_242048600	0.19	MTERFD2	MTERF domain containing 2	6777	0.15
chr1_158987756_158987989	0.19	IFI16	interferon, gamma-inducible protein 16	2409	0.3
chr2_198029847_198029998	0.19	ANKRD44	ankyrin repeat domain 44	17294	0.21
chr2_219746116_219746414	0.19	WNT10A	wingless-type MMTV integration site family, member 10A	618	0.61
chr1_65418325_65418575	0.19	JAK1	Janus kinase 1	13737	0.24
chr20_37487045_37487450	0.19	ENSG00000240474	.	14166	0.19
chrX_55146325_55146476	0.19	PAGE2	P antigen family, member 2 (prostate associated)	30831	0.13
chr7_12771128_12771335	0.19	ENSG00000199470	.	30717	0.2
chr13_42968234_42968447	0.19	AKAP11	A kinase (PRKA) anchor protein 11	122051	0.06
chr17_38758982_38759133	0.19	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	29485	0.12
chr4_89535407_89535597	0.19	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	8557	0.18
chr5_118673350_118673800	0.19	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	4705	0.24
chr10_104253181_104253332	0.19	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	9179	0.1
chr11_121333986_121334216	0.19	RP11-730K11.1		10379	0.24
chr5_31973500_31973651	0.19	ENSG00000266243	.	37310	0.17
chr13_49080309_49080536	0.19	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	26791	0.22
chr5_61626221_61626490	0.19	KIF2A	kinesin heavy chain member 2A	18715	0.23
chr2_128611964_128612115	0.19	POLR2D	polymerase (RNA) II (DNA directed) polypeptide D	3484	0.18
chr5_37841386_37841537	0.19	GDNF	glial cell derived neurotrophic factor	1673	0.47
chr9_41009405_41009618	0.19	ZNF658	zinc finger protein 658	217413	0.02
chr9_4664421_4664621	0.19	SPATA6L	spermatogenesis associated 6-like	1826	0.28
chr4_38672870_38673144	0.19	RP11-617D20.1		6503	0.18
chr4_100737406_100737644	0.19	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	465	0.87
chr4_78729950_78730101	0.19	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	10192	0.27
chr2_71296245_71296452	0.19	NAGK	N-acetylglucosamine kinase	556	0.62
chr1_67677903_67678054	0.19	IL23R	interleukin 23 receptor	4629	0.17
chr4_81049792_81050281	0.18	PRDM8	PR domain containing 8	55403	0.13
chr3_50629992_50630197	0.18	HEMK1	HemK methyltransferase family member 1	15539	0.13
chr2_25531378_25531529	0.18	ENSG00000221445	.	20137	0.2
chr8_95939642_95939793	0.18	TP53INP1	tumor protein p53 inducible nuclear protein 1	13484	0.12
chr1_2065748_2065961	0.18	PRKCZ	protein kinase C, zeta	398	0.8
chr9_66039423_66039674	0.18	ENSG00000202474	.	418714	0.01
chr12_25209086_25209350	0.18	LRMP	lymphoid-restricted membrane protein	3544	0.25
chr16_68309891_68310466	0.18	SLC7A6	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	3296	0.1
chr14_89290472_89290657	0.18	TTC8	tetratricopeptide repeat domain 8	404	0.83
chr15_52964063_52964214	0.18	FAM214A	family with sequence similarity 214, member A	6280	0.23
chr3_13907045_13907277	0.18	WNT7A	wingless-type MMTV integration site family, member 7A	14457	0.22
chr1_12291292_12291653	0.18	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	1348	0.41
chr2_192012454_192012731	0.18	STAT4	signal transducer and activator of transcription 4	3105	0.29
chrX_56595115_56595757	0.18	UBQLN2	ubiquilin 2	5410	0.34
chr2_202766908_202767059	0.18	ENSG00000212184	.	25179	0.16
chr18_43247401_43247693	0.18	SLC14A2	solute carrier family 14 (urea transporter), member 2	1440	0.43
chr13_100037229_100037523	0.18	ENSG00000207719	.	28991	0.17
chr4_140235644_140235795	0.18	ENSG00000200520	.	3813	0.17
chr3_60067021_60067187	0.18	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	109521	0.08
chr9_115444388_115444539	0.18	INIP	INTS3 and NABP interacting protein	35924	0.17
chr14_62549769_62549920	0.18	RP11-355I22.7		27749	0.25
chr9_123650765_123650916	0.18	PHF19	PHD finger protein 19	11234	0.18
chr19_47690366_47690533	0.18	ENSG00000265134	.	39750	0.1
chr19_49590668_49590831	0.18	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	1012	0.26
chr8_134629707_134629903	0.18	ENSG00000212273	.	27163	0.23
chr15_66180156_66180454	0.18	RAB11A	RAB11A, member RAS oncogene family	17954	0.19
chr12_65037920_65038186	0.18	RP11-338E21.3		10746	0.13
chr2_188418719_188418870	0.18	AC007319.1		82	0.77
chr16_89002649_89002800	0.18	RP11-830F9.7		1440	0.29
chr10_43782614_43782967	0.18	RASGEF1A	RasGEF domain family, member 1A	20423	0.2
chrX_8955902_8956053	0.18	FAM9B	family with sequence similarity 9, member B	45139	0.2
chr14_106829247_106829398	0.18	IGHV4-34	immunoglobulin heavy variable 4-34	754	0.24
chr2_73053295_73053446	0.18	EXOC6B	exocyst complex component 6B	200	0.95
chr13_51002906_51003057	0.18	ENSG00000221198	.	65608	0.14
chr9_92138368_92138605	0.18	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	25441	0.19
chr6_43345681_43345832	0.18	ZNF318	zinc finger protein 318	8575	0.15
chr7_37379203_37379459	0.18	ELMO1	engulfment and cell motility 1	3036	0.28
chr7_116651248_116651444	0.18	ST7	suppression of tumorigenicity 7	3596	0.22
chr20_47432015_47432257	0.18	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	12284	0.26
chr10_6333541_6333863	0.18	ENSG00000238366	.	45908	0.13
chr6_37470810_37470961	0.18	CCDC167	coiled-coil domain containing 167	3187	0.27
chr4_81763021_81763172	0.18	BMP3	bone morphogenetic protein 3	189023	0.03
chr2_109598668_109598819	0.18	EDAR	ectodysplasin A receptor	6982	0.3
chr11_117916276_117916450	0.18	ENSG00000272075	.	21589	0.14
chr16_50717313_50717932	0.18	SNX20	sorting nexin 20	2358	0.19
chr6_119116804_119116955	0.18	MCM9	minichromosome maintenance complex component 9	33537	0.2
chr11_68249048_68249199	0.18	PPP6R3	protein phosphatase 6, regulatory subunit 3	20842	0.15
chr17_35309043_35309194	0.18	AATF	apoptosis antagonizing transcription factor	2943	0.17
chr13_42075032_42075183	0.18	RGCC	regulator of cell cycle	43412	0.12
chr2_231582997_231583148	0.17	CAB39	calcium binding protein 39	4809	0.25
chr10_104266820_104266971	0.17	SUFU	suppressor of fused homolog (Drosophila)	3059	0.14
chr15_44970648_44970859	0.17	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	1667	0.29
chr5_156642358_156642695	0.17	CTB-4E7.1		8864	0.13
chr8_144631891_144632307	0.17	RP11-661A12.5		200	0.84
chr17_1776335_1776696	0.17	RPA1	replication protein A1, 70kDa	5814	0.17
chr6_105849452_105849858	0.17	PREP	prolyl endopeptidase	1304	0.59
chr2_161946247_161946703	0.17	TANK	TRAF family member-associated NFKB activator	46944	0.17
chr19_42702815_42703281	0.17	ENSG00000265122	.	5818	0.1
chr13_113526510_113526661	0.17	ATP11A	ATPase, class VI, type 11A	503	0.81
chr4_109091305_109091456	0.17	LEF1	lymphoid enhancer-binding factor 1	1268	0.42
chr16_67191833_67192044	0.17	TRADD	TNFRSF1A-associated via death domain	1786	0.14
chr1_224575229_224575443	0.17	ENSG00000266618	.	10677	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:0001743	optic placode formation(GO:0001743)
0.1	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0060430	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.3	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.3	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0022009	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.3	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0052166	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.3	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.5	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.2	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.2	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0002839	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0043586	tongue development(GO:0043586)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.1	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0090197	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:1901071	glucosamine-containing compound metabolic process(GO:1901071)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.6	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.3	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0032914	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.0	GO:0034391	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.3	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0002832	negative regulation of response to biotic stimulus(GO:0002832)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0021697	cerebellar cortex formation(GO:0021697)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0006582	melanin metabolic process(GO:0006582)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0072487	MSL complex(GO:0072487)
0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	GO:0000145	exocyst(GO:0000145)
0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	GO:0031932	TORC2 complex(GO:0031932)
0.2	GO:0001891	phagocytic cup(GO:0001891)
0.1	GO:0005638	lamin filament(GO:0005638)
0.3	GO:0032039	integrator complex(GO:0032039)
0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.3	GO:0001772	immunological synapse(GO:0001772)
0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	GO:0034451	centriolar satellite(GO:0034451)
0.2	GO:0034464	BBSome(GO:0034464)
0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	GO:0000791	euchromatin(GO:0000791)
0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	GO:0048179	activin receptor complex(GO:0048179)
0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	GO:0032040	small-subunit processome(GO:0032040)
0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	GO:0000242	pericentriolar material(GO:0000242)
0.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	GO:0005686	U2 snRNP(GO:0005686)
0.1	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	GO:0071986	Ragulator complex(GO:0071986)
0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0032300	mismatch repair complex(GO:0032300)
0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
1.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	GO:0030008	TRAPP complex(GO:0030008)
0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.3	GO:0016592	mediator complex(GO:0016592)
0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	GO:0005652	nuclear lamina(GO:0005652)
0.8	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.7	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.4	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.7	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.5	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.0	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0016208	AMP binding(GO:0016208)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.3	PID IL5 PATHWAY	IL5-mediated signaling events
1.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
1.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.9	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	PID MYC PATHWAY	C-MYC pathway
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.0	0.7	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL

Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.80

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif across conditions

Conditions sorted by the z-value of the FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: