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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for FOXF2_FOXJ1

Z-value: 1.09

Motif logo

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Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
FOXF2
ENSG00000137273.3 forkhead box F2
FOXJ1
ENSG00000129654.7 forkhead box J1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_1407221_1407459FOXF2172710.2103290.462.1e-01Click!
chr6_1389149_1389347FOXF28210.656661-0.422.6e-01Click!
chr6_1406853_1407004FOXF2168590.2110140.383.1e-01Click!
chr6_1388815_1389115FOXF211040.5395270.353.6e-01Click!
chr6_1388553_1388704FOXF214410.438898-0.343.7e-01Click!
chr17_74137011_74137327FOXJ12110.695528-0.627.7e-02Click!

Activity of the FOXF2_FOXJ1 motif across conditions

Conditions sorted by the z-value of the FOXF2_FOXJ1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_80354102_80354437 0.83 RP13-20L14.4
4989
 0.1
chr16_49733508_49733659 0.50 ENSG00000221134
 .
 20452
 0.22
chr1_198859851_198860145 0.49 ENSG00000207759
 .
 31716
 0.2
chr6_26350885_26351036 0.48 ENSG00000252399
 .
 2304
 0.16
chr8_13089426_13089577 0.45 DLC1
 deleted in liver cancer 1
 44554
 0.17
chr5_148290573_148290835 0.45 RP11-44B19.1
59199
 0.12
chr10_79669456_79669735 0.45 ENSG00000243446
 .
 2709
 0.24
chr8_19069882_19070033 0.45 SH2D4A
 SH2 domain containing 4A
 101171
 0.08
chr4_119674096_119674247 0.44 SEC24D
 SEC24 family member D
 5626
 0.29
chr7_111078523_111078674 0.44 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
 45627
 0.21
chr4_150925367_150925518 0.43 ENSG00000207121
 .
 69914
 0.11
chr8_108470356_108470589 0.42 ANGPT1
 angiopoietin 1
 36751
 0.24
chr18_60548793_60548944 0.42 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
 21515
 0.2
chr6_56573158_56573456 0.41 DST
 dystonin
 65513
 0.14
chr1_85065842_85065993 0.41 CTBS
 chitobiase, di-N-acetyl-
 25770
 0.17
chr5_14397094_14397245 0.41 TRIO
 trio Rho guanine nucleotide exchange factor
 91388
 0.09
chr9_94539443_94539824 0.41 ENSG00000266855
 .
 141100
 0.05
chr13_33803306_33803457 0.41 STARD13
 StAR-related lipid transfer (START) domain containing 13
 23238
 0.2
chr12_109539613_109539764 0.40 UNG
 uracil-DNA glycosylase
 3765
 0.15
chr6_166985772_166986271 0.40 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 27843
 0.18
chr6_158838381_158838532 0.40 RP11-732M18.2
18863
 0.2
chr18_19904044_19904557 0.40 ENSG00000238907
 .
 63761
 0.11
chr3_64330269_64330420 0.40 PRICKLE2
 prickle homolog 2 (Drosophila)
 76689
 0.1
chr12_66089003_66089154 0.39 HMGA2
 high mobility group AT-hook 2
 128833
 0.05
chr3_189434335_189434486 0.39 TP63
 tumor protein p63
 73039
 0.12
chr3_69469991_69470142 0.39 FRMD4B
 FERM domain containing 4B
 34636
 0.23
chr8_28984494_28984645 0.38 CTD-2647L4.1
12992
 0.15
chr7_134049333_134049484 0.38 SLC35B4
 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
 47605
 0.16
chr17_48137007_48137298 0.37 ITGA3
 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
 3348
 0.18
chr1_162319832_162320115 0.36 ENSG00000207729
 .
 7637
 0.11
chr8_80672969_80673271 0.36 HEY1
 hes-related family bHLH transcription factor with YRPW motif 1
 5590
 0.28
chr1_12483776_12483927 0.36 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 13927
 0.23
chr12_43709758_43710210 0.35 ENSG00000215993
 .
 24601
 0.27
chr12_10794215_10794366 0.35 STYK1
 serine/threonine/tyrosine kinase 1
 12053
 0.16
chr11_29315204_29315355 0.35 ENSG00000211499
 .
 17043
 0.31
chr11_5310917_5311068 0.35 OR51B4
 olfactory receptor, family 51, subfamily B, member 4
 12234
 0.09
chr1_151592190_151592613 0.35 RP11-404E16.1
6562
 0.11
chr2_238365295_238365446 0.35 MLPH
 melanophilin
 28701
 0.15
chr3_119921549_119921940 0.35 ENSG00000206721
 .
 7423
 0.22
chr5_102607577_102607797 0.34 C5orf30
 chromosome 5 open reading frame 30
 12562
 0.23
chr3_72868449_72868731 0.34 SHQ1
 SHQ1, H/ACA ribonucleoprotein assembly factor
 26924
 0.21
chr11_9173045_9173196 0.34 DENND5A
 DENN/MADD domain containing 5A
 834
 0.63
chr4_78093919_78094070 0.34 CCNG2
 cyclin G2
 14415
 0.22
chr1_117908214_117909192 0.34 MAN1A2
 mannosidase, alpha, class 1A, member 2
 1368
 0.58
chr11_27448938_27449230 0.34 RP11-159H22.2
44192
 0.13
chr11_33298506_33298657 0.34 HIPK3
 homeodomain interacting protein kinase 3
 18704
 0.21
chr2_216635749_216635900 0.34 ENSG00000212055
 .
 107818
 0.07
chr7_47515286_47515437 0.34 TNS3
 tensin 3
 5522
 0.34
chr9_97628790_97628941 0.34 RP11-49O14.2
33846
 0.14
chr18_22907594_22907986 0.34 ZNF521
 zinc finger protein 521
 23367
 0.23
chr5_39420581_39420732 0.33 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 4314
 0.32
chr16_22409641_22409792 0.33 CDR2
 cerebellar degeneration-related protein 2, 62kDa
 23305
 0.12
chr16_77392856_77393007 0.33 ADAMTS18
 ADAM metallopeptidase with thrombospondin type 1 motif, 18
 69675
 0.1
chr5_173958937_173959224 0.33 MSX2
 msh homeobox 2
 192456
 0.03
chr2_218354637_218354788 0.33 ENSG00000251982
 .
 238433
 0.02
chr18_8615630_8615858 0.33 RAB12
 RAB12, member RAS oncogene family
 6301
 0.21
chr4_157699893_157700044 0.33 RP11-154F14.2
62543
 0.12
chr14_71368302_71368567 0.32 PCNX
 pecanex homolog (Drosophila)
 5688
 0.31
chr10_80865141_80865370 0.32 ZMIZ1
 zinc finger, MIZ-type containing 1
 36463
 0.19
chr13_60354193_60354344 0.32 DIAPH3-AS1
 DIAPH3 antisense RNA 1
 232617
 0.02
chr14_61244389_61244540 0.32 MNAT1
 MNAT CDK-activating kinase assembly factor 1
 30578
 0.19
chr10_76050762_76050913 0.32 ADK
 adenosine kinase
 114316
 0.06
chr7_5458267_5458922 0.32 AC093620.5
864
 0.36
chr8_18815764_18816021 0.32 ENSG00000201157
 .
 21237
 0.2
chr18_18743331_18743728 0.32 ENSG00000251886
 .
 43062
 0.15
chr3_10412398_10412669 0.32 ENSG00000216135
 .
 23713
 0.13
chr1_210551647_210551798 0.32 ENSG00000200972
 .
 4111
 0.28
chr2_123391337_123391637 0.32 TSN
 translin
 877740
 0.0
chr13_109567579_109568598 0.31 MYO16
 myosin XVI
 29571
 0.26
chr10_45473918_45474188 0.31 C10orf10
 chromosome 10 open reading frame 10
 184
 0.91
chr4_41014654_41014947 0.31 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 1602
 0.41
chr3_149119024_149119417 0.31 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 23214
 0.16
chr1_39575783_39575934 0.31 MACF1
 microtubule-actin crosslinking factor 1
 4775
 0.2
chr1_7870325_7870476 0.31 RP3-467L1.4
17002
 0.14
chr12_29895057_29895338 0.31 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
 41534
 0.21
chr10_44958607_44958758 0.31 CXCL12
 chemokine (C-X-C motif) ligand 12
 78142
 0.11
chr4_170926232_170926383 0.31 MFAP3L
 microfibrillar-associated protein 3-like
 1372
 0.48
chr3_100762310_100762461 0.31 ABI3BP
 ABI family, member 3 (NESH) binding protein
 50026
 0.16
chr21_35705528_35705679 0.31 ENSG00000266007
 .
 28173
 0.13
chr15_71347018_71347169 0.31 THSD4
 thrombospondin, type I, domain containing 4
 42198
 0.16
chr2_202663671_202663822 0.31 CDK15
 cyclin-dependent kinase 15
 7352
 0.16
chr5_37831903_37832054 0.30 GDNF
 glial cell derived neurotrophic factor
 3032
 0.32
chr22_36019288_36019458 0.30 MB
 myoglobin
 28
 0.98
chr4_47566719_47567004 0.30 AC092597.3
4585
 0.3
chr3_143489302_143489453 0.30 SLC9A9
 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
 77923
 0.12
chr1_86034688_86034839 0.30 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 9170
 0.19
chr1_95258755_95258906 0.30 SLC44A3
 solute carrier family 44, member 3
 27068
 0.18
chr17_30049392_30049543 0.30 ENSG00000202026
 .
 8695
 0.23
chr8_124683811_124683962 0.30 KLHL38
 kelch-like family member 38
 18696
 0.19
chr12_46949120_46949271 0.30 SLC38A2
 solute carrier family 38, member 2
 182545
 0.03
chr12_30947570_30947865 0.30 CAPRIN2
 caprin family member 2
 39832
 0.19
chr4_150041484_150041635 0.30 ENSG00000239168
 .
 128774
 0.06
chr21_36950874_36951025 0.30 ENSG00000211590
 .
 142064
 0.05
chr5_38783257_38783408 0.29 RP11-122C5.3
350
 0.92
chr7_33793687_33793838 0.29 RP11-89N17.2
22086
 0.22
chr9_72659789_72660086 0.29 MAMDC2
 MAM domain containing 2
 1440
 0.51
chr11_96042019_96042312 0.29 ENSG00000266192
 .
 32437
 0.17
chr2_36589813_36589964 0.29 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 6274
 0.32
chr1_30556903_30557122 0.29 ENSG00000222787
 .
 199263
 0.03
chr7_114627811_114627962 0.29 MDFIC
 MyoD family inhibitor domain containing
 53962
 0.18
chr2_114635767_114636012 0.29 ACTR3
 ARP3 actin-related protein 3 homolog (yeast)
 11648
 0.21
chr12_47353443_47353741 0.29 PCED1B
 PC-esterase domain containing 1B
 119794
 0.06
chr1_59479598_59479749 0.29 JUN
 jun proto-oncogene
 229888
 0.02
chr17_80355013_80355164 0.29 RP13-20L14.4
4170
 0.11
chr1_94095744_94095895 0.29 BCAR3
 breast cancer anti-estrogen resistance 3
 16165
 0.21
chr12_42958679_42958830 0.29 PRICKLE1
 prickle homolog 1 (Drosophila)
 24724
 0.21
chr17_43407056_43407601 0.28 ENSG00000199953
 .
 2465
 0.22
chr18_74188097_74188669 0.28 ZNF516
 zinc finger protein 516
 14352
 0.17
chr8_99014594_99014745 0.28 MATN2
 matrilin 2
 14103
 0.15
chr12_47165529_47165680 0.28 SLC38A4
 solute carrier family 38, member 4
 2517
 0.44
chr17_26673764_26673915 0.28 TNFAIP1
 tumor necrosis factor, alpha-induced protein 1 (endothelial)
 6407
 0.07
chr8_115953594_115953745 0.28 TRPS1
 trichorhinophalangeal syndrome I
 550779
 0.0
chr5_73497876_73498136 0.28 ENSG00000222551
 .
 69584
 0.13
chr1_161880198_161880487 0.28 OLFML2B
 olfactomedin-like 2B
 74680
 0.09
chr8_129179760_129180073 0.28 ENSG00000221261
 .
 17554
 0.23
chr11_35008663_35008941 0.28 PDHX
 pyruvate dehydrogenase complex, component X
 9471
 0.23
chr15_99398645_99398796 0.28 IGF1R
 insulin-like growth factor 1 receptor
 34850
 0.16
chr3_194880738_194881131 0.28 XXYLT1-AS2
 XXYLT1 antisense RNA 2
 12314
 0.14
chr4_169555148_169555325 0.28 PALLD
 palladin, cytoskeletal associated protein
 2468
 0.31
chr22_32955246_32955397 0.28 LL22NC03-104C7.1
23965
 0.19
chr22_38735164_38735315 0.28 CSNK1E
 casein kinase 1, epsilon
 21150
 0.13
chr6_150177550_150177701 0.28 RP11-350J20.12
4027
 0.14
chr13_44819054_44819205 0.28 SMIM2
 small integral membrane protein 2
 83736
 0.09
chr18_9348065_9348216 0.28 TWSG1
 twisted gastrulation BMP signaling modulator 1
 13292
 0.2
chr9_22683470_22683621 0.28 DMRTA1
 DMRT-like family A1
 236705
 0.02
chr10_73627738_73628072 0.28 PSAP
 prosaposin
 16779
 0.19
chr12_6198255_6198797 0.27 ENSG00000240533
 .
 6610
 0.23
chr17_4109949_4110100 0.27 ENSG00000207390
 .
 13961
 0.13
chr8_57633478_57633629 0.27 ENSG00000206975
 .
 196090
 0.03
chr3_171998152_171998303 0.27 AC092964.2
 Uncharacterized protein
 21459
 0.19
chr20_52353487_52354058 0.27 ENSG00000238468
 .
 68475
 0.12
chr20_9389511_9389662 0.27 PLCB4
 phospholipase C, beta 4
 101139
 0.07
chr10_124066964_124067115 0.27 BTBD16
 BTB (POZ) domain containing 16
 36218
 0.14
chr7_78159625_78159776 0.27 MAGI2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 240696
 0.02
chr7_42184494_42184645 0.27 GLI3
 GLI family zinc finger 3
 82751
 0.12
chr18_9017327_9018234 0.27 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
 84848
 0.08
chr7_95239146_95239504 0.27 AC002451.3
217
 0.94
chr3_47435871_47436022 0.27 PTPN23
 protein tyrosine phosphatase, non-receptor type 23
 13436
 0.15
chr8_104117881_104118032 0.27 ENSG00000265667
 .
 13007
 0.13
chr3_187990037_187990188 0.27 LPP
 LIM domain containing preferred translocation partner in lipoma
 32460
 0.22
chr6_12577482_12577633 0.27 PHACTR1
 phosphatase and actin regulator 1
 140336
 0.05
chr7_42147315_42147466 0.27 GLI3
 GLI family zinc finger 3
 119930
 0.07
chrX_71489517_71489668 0.27 RPS4X
 ribosomal protein S4, X-linked
 7506
 0.14
chr4_55147977_55148291 0.27 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 38392
 0.21
chr5_143075483_143075634 0.27 ENSG00000266478
 .
 16133
 0.26
chr11_66739265_66739416 0.27 C11orf86
 chromosome 11 open reading frame 86
 3408
 0.16
chr12_13043607_13043874 0.27 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 24
 0.97
chr14_51242480_51242631 0.27 NIN
 ninein (GSK3B interacting protein)
 9042
 0.17
chr4_13987753_13987904 0.27 ENSG00000252092
 .
 327577
 0.01
chr12_93483466_93483617 0.27 ENSG00000221617
 .
 7486
 0.23
chr1_61803481_61803729 0.27 NFIA
 nuclear factor I/A
 14517
 0.3
chr17_30429974_30430125 0.27 RP11-640N20.8
8098
 0.14
chr4_96471329_96471480 0.27 UNC5C
 unc-5 homolog C (C. elegans)
 1047
 0.43
chr5_134475910_134476061 0.27 PITX1
 paired-like homeodomain 1
 105482
 0.06
chr10_98727488_98727639 0.27 C10orf12
 chromosome 10 open reading frame 12
 13478
 0.19
chr4_88949160_88949362 0.26 PKD2
 polycystic kidney disease 2 (autosomal dominant)
 15152
 0.19
chr1_183009603_183009956 0.26 LAMC1
 laminin, gamma 1 (formerly LAMB2)
 17184
 0.19
chr4_157242892_157243172 0.26 ENSG00000221189
 .
 25234
 0.27
chr2_47243580_47243731 0.26 AC093732.1
24008
 0.16
chr12_52078091_52078242 0.26 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
 2041
 0.42
chr2_218715975_218716307 0.26 TNS1
 tensin 1
 9258
 0.27
chr2_27516048_27516199 0.26 TRIM54
 tripartite motif containing 54
 10793
 0.08
chr12_66290144_66290295 0.26 RP11-366L20.2
 Uncharacterized protein
 14272
 0.17
chr4_39616282_39616433 0.26 ENSG00000252796
 .
 6275
 0.19
chr12_67753116_67753506 0.26 CAND1
 cullin-associated and neddylation-dissociated 1
 60559
 0.16
chr11_74724874_74725025 0.26 NEU3
 sialidase 3 (membrane sialidase)
 24959
 0.14
chr3_59752377_59752528 0.26 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 205131
 0.03
chr12_123448783_123448934 0.26 ABCB9
 ATP-binding cassette, sub-family B (MDR/TAP), member 9
 2149
 0.23
chr6_117813949_117814100 0.26 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 10199
 0.18
chr1_39608036_39608283 0.26 ENSG00000222378
 .
 11809
 0.17
chr18_55317311_55317462 0.26 RP11-35G9.3
10699
 0.16
chr20_1796404_1796650 0.26 SIRPA
 signal-regulatory protein alpha
 78627
 0.09
chr6_52409613_52409764 0.26 TRAM2
 translocation associated membrane protein 2
 32025
 0.2
chr6_116879356_116879507 0.26 FAM26D
 family with sequence similarity 26, member D
 4518
 0.16
chr3_37156478_37156973 0.25 ENSG00000206645
 .
 22000
 0.14
chr5_67752834_67752985 0.25 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 164513
 0.04
chr5_119935266_119935417 0.25 PRR16
 proline rich 16
 17442
 0.29
chr10_3259828_3259979 0.25 PITRM1
 pitrilysin metallopeptidase 1
 44900
 0.18
chr12_22886601_22886752 0.25 ETNK1
 ethanolamine kinase 1
 108385
 0.07
chr10_6764254_6764548 0.25 PRKCQ
 protein kinase C, theta
 142138
 0.05
chr10_112083656_112083807 0.25 SMNDC1
 survival motor neuron domain containing 1
 19022
 0.23
chr2_10113482_10113633 0.25 GRHL1
 grainyhead-like 1 (Drosophila)
 21730
 0.16
chr4_38084935_38085086 0.25 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 37518
 0.21
chr10_71206366_71206517 0.25 TSPAN15
 tetraspanin 15
 4788
 0.23
chr1_45412695_45413130 0.25 ENSG00000253039
 .
 14917
 0.13
chr9_115947226_115947377 0.25 SLC31A2
 solute carrier family 31 (copper transporter), member 2
 34079
 0.13
chr9_91610255_91610406 0.25 S1PR3
 sphingosine-1-phosphate receptor 3
 1091
 0.53
chr1_170001529_170001680 0.25 KIFAP3
 kinesin-associated protein 3
 6562
 0.21
chr3_149738282_149738433 0.25 PFN2
 profilin 2
 2241
 0.29
chr10_31934113_31934264 0.25 ENSG00000222412
 .
 110876
 0.07
chr5_60625410_60625800 0.25 ZSWIM6
 zinc finger, SWIM-type containing 6
 2495
 0.42
chr6_16676788_16676939 0.25 RP1-151F17.1
84506
 0.1
chr9_90215657_90216062 0.24 DAPK1-IT1
 DAPK1 intronic transcript 1 (non-protein coding)
 47490
 0.16
chr6_140087291_140087442 0.24 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 391609
 0.01
chr7_142171579_142172312 0.24 PRSS3P3
 protease, serine, 3 pseudogene 3
 182336
 0.03
chr2_12959099_12960371 0.24 ENSG00000264370
 .
 82242
 0.11
chr6_15328781_15329139 0.24 ENSG00000201519
 .
 4257
 0.25
chr3_31419139_31419290 0.24 ENSG00000238727
 .
 18215
 0.28
chr9_6433707_6433858 0.24 UHRF2
 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
 12751
 0.18
chr9_113597331_113597482 0.24 MUSK
 muscle, skeletal, receptor tyrosine kinase
 59779
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0035929 steroid hormone secretion(GO:0035929)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.0 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0010662 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0060502 epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.2 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.0 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.0 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones