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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXF2_FOXJ1

Z-value: 1.09

Motif logo

Transcription factors associated with FOXF2_FOXJ1

Gene Symbol	Gene ID	Gene Info
FOXF2 Ensembl NCBI GeneCards UniProt	ENSG00000137273.3	FOXF2
FOXJ1 Ensembl NCBI GeneCards UniProt	ENSG00000129654.7	FOXJ1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FOXF2	chr6_1407221_1407459	17271	0.210329	0.46	2.1e-01	Click!
FOXF2	chr6_1389149_1389347	821	0.656661	-0.42	2.6e-01	Click!
FOXF2	chr6_1406853_1407004	16859	0.211014	0.38	3.1e-01	Click!
FOXF2	chr6_1388815_1389115	1104	0.539527	0.35	3.6e-01	Click!
FOXF2	chr6_1388553_1388704	1441	0.438898	-0.34	3.7e-01	Click!
FOXJ1	chr17_74137011_74137327	211	0.695528	-0.62	7.7e-02	Click!

Activity of the FOXF2_FOXJ1 motif across conditions

Conditions sorted by the z-value of the FOXF2_FOXJ1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_80354102_80354437	0.83	RP13-20L14.4		4989	0.1
chr16_49733508_49733659	0.50	ENSG00000221134	.	20452	0.22
chr1_198859851_198860145	0.49	ENSG00000207759	.	31716	0.2
chr6_26350885_26351036	0.48	ENSG00000252399	.	2304	0.16
chr8_13089426_13089577	0.45	DLC1	deleted in liver cancer 1	44554	0.17
chr5_148290573_148290835	0.45	RP11-44B19.1		59199	0.12
chr10_79669456_79669735	0.45	ENSG00000243446	.	2709	0.24
chr8_19069882_19070033	0.45	SH2D4A	SH2 domain containing 4A	101171	0.08
chr4_119674096_119674247	0.44	SEC24D	SEC24 family member D	5626	0.29
chr7_111078523_111078674	0.44	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	45627	0.21
chr4_150925367_150925518	0.43	ENSG00000207121	.	69914	0.11
chr8_108470356_108470589	0.42	ANGPT1	angiopoietin 1	36751	0.24
chr18_60548793_60548944	0.42	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	21515	0.2
chr6_56573158_56573456	0.41	DST	dystonin	65513	0.14
chr1_85065842_85065993	0.41	CTBS	chitobiase, di-N-acetyl-	25770	0.17
chr5_14397094_14397245	0.41	TRIO	trio Rho guanine nucleotide exchange factor	91388	0.09
chr9_94539443_94539824	0.41	ENSG00000266855	.	141100	0.05
chr13_33803306_33803457	0.41	STARD13	StAR-related lipid transfer (START) domain containing 13	23238	0.2
chr12_109539613_109539764	0.40	UNG	uracil-DNA glycosylase	3765	0.15
chr6_166985772_166986271	0.40	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	27843	0.18
chr6_158838381_158838532	0.40	RP11-732M18.2		18863	0.2
chr18_19904044_19904557	0.40	ENSG00000238907	.	63761	0.11
chr3_64330269_64330420	0.40	PRICKLE2	prickle homolog 2 (Drosophila)	76689	0.1
chr12_66089003_66089154	0.39	HMGA2	high mobility group AT-hook 2	128833	0.05
chr3_189434335_189434486	0.39	TP63	tumor protein p63	73039	0.12
chr3_69469991_69470142	0.39	FRMD4B	FERM domain containing 4B	34636	0.23
chr8_28984494_28984645	0.38	CTD-2647L4.1		12992	0.15
chr7_134049333_134049484	0.38	SLC35B4	solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4	47605	0.16
chr17_48137007_48137298	0.37	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	3348	0.18
chr1_162319832_162320115	0.36	ENSG00000207729	.	7637	0.11
chr8_80672969_80673271	0.36	HEY1	hes-related family bHLH transcription factor with YRPW motif 1	5590	0.28
chr1_12483776_12483927	0.36	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	13927	0.23
chr12_43709758_43710210	0.35	ENSG00000215993	.	24601	0.27
chr12_10794215_10794366	0.35	STYK1	serine/threonine/tyrosine kinase 1	12053	0.16
chr11_29315204_29315355	0.35	ENSG00000211499	.	17043	0.31
chr11_5310917_5311068	0.35	OR51B4	olfactory receptor, family 51, subfamily B, member 4	12234	0.09
chr1_151592190_151592613	0.35	RP11-404E16.1		6562	0.11
chr2_238365295_238365446	0.35	MLPH	melanophilin	28701	0.15
chr3_119921549_119921940	0.35	ENSG00000206721	.	7423	0.22
chr5_102607577_102607797	0.34	C5orf30	chromosome 5 open reading frame 30	12562	0.23
chr3_72868449_72868731	0.34	SHQ1	SHQ1, H/ACA ribonucleoprotein assembly factor	26924	0.21
chr11_9173045_9173196	0.34	DENND5A	DENN/MADD domain containing 5A	834	0.63
chr4_78093919_78094070	0.34	CCNG2	cyclin G2	14415	0.22
chr1_117908214_117909192	0.34	MAN1A2	mannosidase, alpha, class 1A, member 2	1368	0.58
chr11_27448938_27449230	0.34	RP11-159H22.2		44192	0.13
chr11_33298506_33298657	0.34	HIPK3	homeodomain interacting protein kinase 3	18704	0.21
chr2_216635749_216635900	0.34	ENSG00000212055	.	107818	0.07
chr7_47515286_47515437	0.34	TNS3	tensin 3	5522	0.34
chr9_97628790_97628941	0.34	RP11-49O14.2		33846	0.14
chr18_22907594_22907986	0.34	ZNF521	zinc finger protein 521	23367	0.23
chr5_39420581_39420732	0.33	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	4314	0.32
chr16_22409641_22409792	0.33	CDR2	cerebellar degeneration-related protein 2, 62kDa	23305	0.12
chr16_77392856_77393007	0.33	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	69675	0.1
chr5_173958937_173959224	0.33	MSX2	msh homeobox 2	192456	0.03
chr2_218354637_218354788	0.33	ENSG00000251982	.	238433	0.02
chr18_8615630_8615858	0.33	RAB12	RAB12, member RAS oncogene family	6301	0.21
chr4_157699893_157700044	0.33	RP11-154F14.2		62543	0.12
chr14_71368302_71368567	0.32	PCNX	pecanex homolog (Drosophila)	5688	0.31
chr10_80865141_80865370	0.32	ZMIZ1	zinc finger, MIZ-type containing 1	36463	0.19
chr13_60354193_60354344	0.32	DIAPH3-AS1	DIAPH3 antisense RNA 1	232617	0.02
chr14_61244389_61244540	0.32	MNAT1	MNAT CDK-activating kinase assembly factor 1	30578	0.19
chr10_76050762_76050913	0.32	ADK	adenosine kinase	114316	0.06
chr7_5458267_5458922	0.32	AC093620.5		864	0.36
chr8_18815764_18816021	0.32	ENSG00000201157	.	21237	0.2
chr18_18743331_18743728	0.32	ENSG00000251886	.	43062	0.15
chr3_10412398_10412669	0.32	ENSG00000216135	.	23713	0.13
chr1_210551647_210551798	0.32	ENSG00000200972	.	4111	0.28
chr2_123391337_123391637	0.32	TSN	translin	877740	0.0
chr13_109567579_109568598	0.31	MYO16	myosin XVI	29571	0.26
chr10_45473918_45474188	0.31	C10orf10	chromosome 10 open reading frame 10	184	0.91
chr4_41014654_41014947	0.31	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	1602	0.41
chr3_149119024_149119417	0.31	TM4SF1-AS1	TM4SF1 antisense RNA 1	23214	0.16
chr1_39575783_39575934	0.31	MACF1	microtubule-actin crosslinking factor 1	4775	0.2
chr1_7870325_7870476	0.31	RP3-467L1.4		17002	0.14
chr12_29895057_29895338	0.31	TMTC1	transmembrane and tetratricopeptide repeat containing 1	41534	0.21
chr10_44958607_44958758	0.31	CXCL12	chemokine (C-X-C motif) ligand 12	78142	0.11
chr4_170926232_170926383	0.31	MFAP3L	microfibrillar-associated protein 3-like	1372	0.48
chr3_100762310_100762461	0.31	ABI3BP	ABI family, member 3 (NESH) binding protein	50026	0.16
chr21_35705528_35705679	0.31	ENSG00000266007	.	28173	0.13
chr15_71347018_71347169	0.31	THSD4	thrombospondin, type I, domain containing 4	42198	0.16
chr2_202663671_202663822	0.31	CDK15	cyclin-dependent kinase 15	7352	0.16
chr5_37831903_37832054	0.30	GDNF	glial cell derived neurotrophic factor	3032	0.32
chr22_36019288_36019458	0.30	MB	myoglobin	28	0.98
chr4_47566719_47567004	0.30	AC092597.3		4585	0.3
chr3_143489302_143489453	0.30	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	77923	0.12
chr1_86034688_86034839	0.30	DDAH1	dimethylarginine dimethylaminohydrolase 1	9170	0.19
chr1_95258755_95258906	0.30	SLC44A3	solute carrier family 44, member 3	27068	0.18
chr17_30049392_30049543	0.30	ENSG00000202026	.	8695	0.23
chr8_124683811_124683962	0.30	KLHL38	kelch-like family member 38	18696	0.19
chr12_46949120_46949271	0.30	SLC38A2	solute carrier family 38, member 2	182545	0.03
chr12_30947570_30947865	0.30	CAPRIN2	caprin family member 2	39832	0.19
chr4_150041484_150041635	0.30	ENSG00000239168	.	128774	0.06
chr21_36950874_36951025	0.30	ENSG00000211590	.	142064	0.05
chr5_38783257_38783408	0.29	RP11-122C5.3		350	0.92
chr7_33793687_33793838	0.29	RP11-89N17.2		22086	0.22
chr9_72659789_72660086	0.29	MAMDC2	MAM domain containing 2	1440	0.51
chr11_96042019_96042312	0.29	ENSG00000266192	.	32437	0.17
chr2_36589813_36589964	0.29	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	6274	0.32
chr1_30556903_30557122	0.29	ENSG00000222787	.	199263	0.03
chr7_114627811_114627962	0.29	MDFIC	MyoD family inhibitor domain containing	53962	0.18
chr2_114635767_114636012	0.29	ACTR3	ARP3 actin-related protein 3 homolog (yeast)	11648	0.21
chr12_47353443_47353741	0.29	PCED1B	PC-esterase domain containing 1B	119794	0.06
chr1_59479598_59479749	0.29	JUN	jun proto-oncogene	229888	0.02
chr17_80355013_80355164	0.29	RP13-20L14.4		4170	0.11
chr1_94095744_94095895	0.29	BCAR3	breast cancer anti-estrogen resistance 3	16165	0.21
chr12_42958679_42958830	0.29	PRICKLE1	prickle homolog 1 (Drosophila)	24724	0.21
chr17_43407056_43407601	0.28	ENSG00000199953	.	2465	0.22
chr18_74188097_74188669	0.28	ZNF516	zinc finger protein 516	14352	0.17
chr8_99014594_99014745	0.28	MATN2	matrilin 2	14103	0.15
chr12_47165529_47165680	0.28	SLC38A4	solute carrier family 38, member 4	2517	0.44
chr17_26673764_26673915	0.28	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	6407	0.07
chr8_115953594_115953745	0.28	TRPS1	trichorhinophalangeal syndrome I	550779	0.0
chr5_73497876_73498136	0.28	ENSG00000222551	.	69584	0.13
chr1_161880198_161880487	0.28	OLFML2B	olfactomedin-like 2B	74680	0.09
chr8_129179760_129180073	0.28	ENSG00000221261	.	17554	0.23
chr11_35008663_35008941	0.28	PDHX	pyruvate dehydrogenase complex, component X	9471	0.23
chr15_99398645_99398796	0.28	IGF1R	insulin-like growth factor 1 receptor	34850	0.16
chr3_194880738_194881131	0.28	XXYLT1-AS2	XXYLT1 antisense RNA 2	12314	0.14
chr4_169555148_169555325	0.28	PALLD	palladin, cytoskeletal associated protein	2468	0.31
chr22_32955246_32955397	0.28	LL22NC03-104C7.1		23965	0.19
chr22_38735164_38735315	0.28	CSNK1E	casein kinase 1, epsilon	21150	0.13
chr6_150177550_150177701	0.28	RP11-350J20.12		4027	0.14
chr13_44819054_44819205	0.28	SMIM2	small integral membrane protein 2	83736	0.09
chr18_9348065_9348216	0.28	TWSG1	twisted gastrulation BMP signaling modulator 1	13292	0.2
chr9_22683470_22683621	0.28	DMRTA1	DMRT-like family A1	236705	0.02
chr10_73627738_73628072	0.28	PSAP	prosaposin	16779	0.19
chr12_6198255_6198797	0.27	ENSG00000240533	.	6610	0.23
chr17_4109949_4110100	0.27	ENSG00000207390	.	13961	0.13
chr8_57633478_57633629	0.27	ENSG00000206975	.	196090	0.03
chr3_171998152_171998303	0.27	AC092964.2	Uncharacterized protein	21459	0.19
chr20_52353487_52354058	0.27	ENSG00000238468	.	68475	0.12
chr20_9389511_9389662	0.27	PLCB4	phospholipase C, beta 4	101139	0.07
chr10_124066964_124067115	0.27	BTBD16	BTB (POZ) domain containing 16	36218	0.14
chr7_78159625_78159776	0.27	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	240696	0.02
chr7_42184494_42184645	0.27	GLI3	GLI family zinc finger 3	82751	0.12
chr18_9017327_9018234	0.27	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	84848	0.08
chr7_95239146_95239504	0.27	AC002451.3		217	0.94
chr3_47435871_47436022	0.27	PTPN23	protein tyrosine phosphatase, non-receptor type 23	13436	0.15
chr8_104117881_104118032	0.27	ENSG00000265667	.	13007	0.13
chr3_187990037_187990188	0.27	LPP	LIM domain containing preferred translocation partner in lipoma	32460	0.22
chr6_12577482_12577633	0.27	PHACTR1	phosphatase and actin regulator 1	140336	0.05
chr7_42147315_42147466	0.27	GLI3	GLI family zinc finger 3	119930	0.07
chrX_71489517_71489668	0.27	RPS4X	ribosomal protein S4, X-linked	7506	0.14
chr4_55147977_55148291	0.27	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	38392	0.21
chr5_143075483_143075634	0.27	ENSG00000266478	.	16133	0.26
chr11_66739265_66739416	0.27	C11orf86	chromosome 11 open reading frame 86	3408	0.16
chr12_13043607_13043874	0.27	GPRC5A	G protein-coupled receptor, family C, group 5, member A	24	0.97
chr14_51242480_51242631	0.27	NIN	ninein (GSK3B interacting protein)	9042	0.17
chr4_13987753_13987904	0.27	ENSG00000252092	.	327577	0.01
chr12_93483466_93483617	0.27	ENSG00000221617	.	7486	0.23
chr1_61803481_61803729	0.27	NFIA	nuclear factor I/A	14517	0.3
chr17_30429974_30430125	0.27	RP11-640N20.8		8098	0.14
chr4_96471329_96471480	0.27	UNC5C	unc-5 homolog C (C. elegans)	1047	0.43
chr5_134475910_134476061	0.27	PITX1	paired-like homeodomain 1	105482	0.06
chr10_98727488_98727639	0.27	C10orf12	chromosome 10 open reading frame 12	13478	0.19
chr4_88949160_88949362	0.26	PKD2	polycystic kidney disease 2 (autosomal dominant)	15152	0.19
chr1_183009603_183009956	0.26	LAMC1	laminin, gamma 1 (formerly LAMB2)	17184	0.19
chr4_157242892_157243172	0.26	ENSG00000221189	.	25234	0.27
chr2_47243580_47243731	0.26	AC093732.1		24008	0.16
chr12_52078091_52078242	0.26	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit	2041	0.42
chr2_218715975_218716307	0.26	TNS1	tensin 1	9258	0.27
chr2_27516048_27516199	0.26	TRIM54	tripartite motif containing 54	10793	0.08
chr12_66290144_66290295	0.26	RP11-366L20.2	Uncharacterized protein	14272	0.17
chr4_39616282_39616433	0.26	ENSG00000252796	.	6275	0.19
chr12_67753116_67753506	0.26	CAND1	cullin-associated and neddylation-dissociated 1	60559	0.16
chr11_74724874_74725025	0.26	NEU3	sialidase 3 (membrane sialidase)	24959	0.14
chr3_59752377_59752528	0.26	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	205131	0.03
chr12_123448783_123448934	0.26	ABCB9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	2149	0.23
chr6_117813949_117814100	0.26	DCBLD1	discoidin, CUB and LCCL domain containing 1	10199	0.18
chr1_39608036_39608283	0.26	ENSG00000222378	.	11809	0.17
chr18_55317311_55317462	0.26	RP11-35G9.3		10699	0.16
chr20_1796404_1796650	0.26	SIRPA	signal-regulatory protein alpha	78627	0.09
chr6_52409613_52409764	0.26	TRAM2	translocation associated membrane protein 2	32025	0.2
chr6_116879356_116879507	0.26	FAM26D	family with sequence similarity 26, member D	4518	0.16
chr3_37156478_37156973	0.25	ENSG00000206645	.	22000	0.14
chr5_67752834_67752985	0.25	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	164513	0.04
chr5_119935266_119935417	0.25	PRR16	proline rich 16	17442	0.29
chr10_3259828_3259979	0.25	PITRM1	pitrilysin metallopeptidase 1	44900	0.18
chr12_22886601_22886752	0.25	ETNK1	ethanolamine kinase 1	108385	0.07
chr10_6764254_6764548	0.25	PRKCQ	protein kinase C, theta	142138	0.05
chr10_112083656_112083807	0.25	SMNDC1	survival motor neuron domain containing 1	19022	0.23
chr2_10113482_10113633	0.25	GRHL1	grainyhead-like 1 (Drosophila)	21730	0.16
chr4_38084935_38085086	0.25	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	37518	0.21
chr10_71206366_71206517	0.25	TSPAN15	tetraspanin 15	4788	0.23
chr1_45412695_45413130	0.25	ENSG00000253039	.	14917	0.13
chr9_115947226_115947377	0.25	SLC31A2	solute carrier family 31 (copper transporter), member 2	34079	0.13
chr9_91610255_91610406	0.25	S1PR3	sphingosine-1-phosphate receptor 3	1091	0.53
chr1_170001529_170001680	0.25	KIFAP3	kinesin-associated protein 3	6562	0.21
chr3_149738282_149738433	0.25	PFN2	profilin 2	2241	0.29
chr10_31934113_31934264	0.25	ENSG00000222412	.	110876	0.07
chr5_60625410_60625800	0.25	ZSWIM6	zinc finger, SWIM-type containing 6	2495	0.42
chr6_16676788_16676939	0.25	RP1-151F17.1		84506	0.1
chr9_90215657_90216062	0.24	DAPK1-IT1	DAPK1 intronic transcript 1 (non-protein coding)	47490	0.16
chr6_140087291_140087442	0.24	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	391609	0.01
chr7_142171579_142172312	0.24	PRSS3P3	protease, serine, 3 pseudogene 3	182336	0.03
chr2_12959099_12960371	0.24	ENSG00000264370	.	82242	0.11
chr6_15328781_15329139	0.24	ENSG00000201519	.	4257	0.25
chr3_31419139_31419290	0.24	ENSG00000238727	.	18215	0.28
chr9_6433707_6433858	0.24	UHRF2	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	12751	0.18
chr9_113597331_113597482	0.24	MUSK	muscle, skeletal, receptor tyrosine kinase	59779	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.3	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.2	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.1	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.0	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0034405	response to fluid shear stress(GO:0034405)
0.0	0.0	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.2	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.0	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.2	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.4	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0005902	microvillus(GO:0005902)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.0	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.5	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones