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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXJ2

Z-value: 0.90

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Transcription factors associated with FOXJ2

Gene Symbol	Gene ID	Gene Info
FOXJ2 Ensembl NCBI GeneCards UniProt	ENSG00000065970.4	FOXJ2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FOXJ2	chr12_8184554_8184838	603	0.697667	-0.60	8.7e-02	Click!
FOXJ2	chr12_8171134_8171285	14090	0.151001	0.60	9.0e-02	Click!
FOXJ2	chr12_8188502_8188653	2621	0.229622	0.55	1.3e-01	Click!
FOXJ2	chr12_8190705_8190938	4865	0.174773	0.54	1.3e-01	Click!
FOXJ2	chr12_8182937_8183088	2287	0.254019	0.48	1.9e-01	Click!

Activity of the FOXJ2 motif across conditions

Conditions sorted by the z-value of the FOXJ2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_26704220_26704518	0.35	C7orf71	chromosome 7 open reading frame 71	26879	0.23
chr3_187627904_187628178	0.28	BCL6	B-cell CLL/lymphoma 6	164526	0.04
chr11_64078371_64078522	0.28	ESRRA	estrogen-related receptor alpha	3310	0.08
chr12_57077760_57078152	0.26	PTGES3	prostaglandin E synthase 3 (cytosolic)	3990	0.14
chr12_7123219_7123370	0.24	LPCAT3	lysophosphatidylcholine acyltransferase 3	2520	0.14
chr3_31975446_31975713	0.23	OSBPL10	oxysterol binding protein-like 10	47213	0.14
chr18_72895850_72896001	0.23	ZADH2	zinc binding alcohol dehydrogenase domain containing 2	21543	0.23
chr11_32916634_32916991	0.22	QSER1	glutamine and serine rich 1	2088	0.38
chr7_26900574_26900830	0.22	SKAP2	src kinase associated phosphoprotein 2	3463	0.33
chr10_116153047_116153198	0.22	AFAP1L2	actin filament associated protein 1-like 2	11117	0.23
chr2_110402358_110402509	0.21	SOWAHC	sosondowah ankyrin repeat domain family member C	30522	0.16
chr8_122360906_122361134	0.21	ENSG00000221644	.	161888	0.04
chr3_172281504_172281789	0.20	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	40349	0.16
chr18_74197341_74197735	0.20	ZNF516	zinc finger protein 516	5197	0.19
chr1_24284423_24284685	0.20	CNR2	cannabinoid receptor 2 (macrophage)	995	0.32
chr6_116420339_116420630	0.20	NT5DC1	5'-nucleotidase domain containing 1	1528	0.38
chr6_138913719_138913963	0.20	NHSL1	NHS-like 1	20164	0.24
chr22_38294132_38294330	0.20	ENSG00000207227	.	6877	0.1
chr1_43411413_43411601	0.19	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	12993	0.18
chr20_1784583_1784806	0.19	SIRPA	signal-regulatory protein alpha	90460	0.07
chr18_46925702_46925885	0.19	DYM	dymeclin	20774	0.15
chr3_112365839_112365990	0.19	CCDC80	coiled-coil domain containing 80	5767	0.27
chr14_91607015_91607166	0.19	C14orf159	chromosome 14 open reading frame 159	7032	0.16
chr6_37591161_37591419	0.19	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	22860	0.22
chr8_66629977_66630128	0.19	RP11-707M3.3		3039	0.28
chr3_51534436_51534590	0.18	VPRBP	Vpr (HIV-1) binding protein	503	0.82
chr4_143345126_143345417	0.18	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	7141	0.35
chr3_12435782_12435933	0.18	PPARG	peroxisome proliferator-activated receptor gamma	42886	0.15
chr20_17836751_17837016	0.18	ENSG00000221220	.	13656	0.2
chr12_14667928_14668079	0.18	RP11-502N13.2		15082	0.16
chr11_92585503_92585654	0.18	FAT3	FAT atypical cadherin 3	8072	0.28
chr14_66239499_66239650	0.18	FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	103441	0.08
chr14_68714875_68715122	0.17	ENSG00000243546	.	11742	0.27
chr3_23366935_23367198	0.17	ENSG00000206728	.	51768	0.15
chr19_17523343_17523496	0.17	MVB12A	multivesicular body subunit 12A	6465	0.08
chr6_16652590_16652871	0.17	RP1-151F17.1		108639	0.07
chr12_111807867_111808018	0.17	FAM109A	family with sequence similarity 109, member A	1017	0.54
chr11_46861994_46862145	0.17	CKAP5	cytoskeleton associated protein 5	5711	0.17
chr19_47371603_47371754	0.17	AP2S1	adaptor-related protein complex 2, sigma 1 subunit	17429	0.16
chr4_105416352_105416699	0.17	CXXC4	CXXC finger protein 4	474	0.81
chr11_10609627_10609795	0.16	MRVI1-AS1	MRVI1 antisense RNA 1	5033	0.19
chr22_18539461_18539695	0.16	XXbac-B476C20.9		20985	0.13
chr5_39148697_39148939	0.16	AC008964.1		43460	0.16
chr22_43322871_43323022	0.16	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	18933	0.21
chr3_185888596_185888848	0.16	ETV5	ets variant 5	60615	0.13
chr6_150463083_150463314	0.16	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C	1014	0.56
chr4_90756774_90756958	0.16	SNCA	synuclein, alpha (non A4 component of amyloid precursor)	20	0.94
chr9_124116966_124117153	0.16	AL161784.1	Uncharacterized protein	13434	0.14
chr5_127295498_127295826	0.16	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	123796	0.06
chr2_29339694_29340047	0.16	CLIP4	CAP-GLY domain containing linker protein family, member 4	1191	0.44
chr2_128554283_128554484	0.16	ENSG00000201470	.	2189	0.25
chr17_6581080_6581264	0.16	SLC13A5	solute carrier family 13 (sodium-dependent citrate transporter), member 5	13031	0.1
chr10_60935903_60936054	0.16	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	372	0.92
chr10_74989869_74990020	0.16	DNAJC9-AS1	DNAJC9 antisense RNA 1	17174	0.09
chr1_32040359_32040510	0.16	RP11-73M7.1		740	0.54
chr6_116772996_116773147	0.16	ENSG00000265516	.	5914	0.14
chr15_59461940_59462091	0.16	ENSG00000253030	.	1446	0.28
chrX_129254186_129254397	0.15	ELF4	E74-like factor 4 (ets domain transcription factor)	9600	0.2
chr10_14823935_14824305	0.15	FAM107B	family with sequence similarity 107, member B	7224	0.22
chr6_130924438_130924589	0.15	ENSG00000202438	.	29256	0.24
chr7_41548338_41548489	0.15	INHBA-AS1	INHBA antisense RNA 1	185101	0.03
chr14_71349673_71349956	0.15	PCNX	pecanex homolog (Drosophila)	24308	0.24
chr14_103838670_103838952	0.15	MARK3	MAP/microtubule affinity-regulating kinase 3	12918	0.15
chr12_680792_680943	0.15	RP5-1154L15.2		14785	0.13
chr10_97047146_97047394	0.15	PDLIM1	PDZ and LIM domain 1	3511	0.3
chr4_38387684_38387835	0.15	ENSG00000221495	.	147525	0.04
chr7_20830813_20830964	0.15	SP8	Sp8 transcription factor	4383	0.36
chr10_102671101_102671252	0.15	FAM178A	family with sequence similarity 178, member A	1150	0.31
chr1_81697056_81697207	0.15	ENSG00000223026	.	20343	0.27
chr16_57414802_57415099	0.15	CX3CL1	chemokine (C-X3-C motif) ligand 1	4066	0.16
chr8_18672395_18672546	0.15	ENSG00000251963	.	5334	0.24
chr9_124375460_124375641	0.15	RP11-524G24.2		37057	0.16
chr4_159705947_159706098	0.15	ENSG00000206703	.	9826	0.19
chr1_214666364_214666654	0.15	PTPN14	protein tyrosine phosphatase, non-receptor type 14	28363	0.24
chr4_15033017_15033168	0.15	CPEB2	cytoplasmic polyadenylation element binding protein 2	22665	0.25
chr3_70890218_70890369	0.15	ENSG00000206939	.	32792	0.2
chr15_99211968_99212377	0.15	IGF1R	insulin-like growth factor 1 receptor	19899	0.21
chr9_91047692_91047843	0.15	SPIN1	spindlin 1	44421	0.17
chr5_170738876_170739099	0.15	TLX3	T-cell leukemia homeobox 3	2699	0.26
chr12_72240351_72240502	0.15	TBC1D15	TBC1 domain family, member 15	6868	0.27
chr13_110651731_110651882	0.15	ENSG00000201161	.	84363	0.1
chr7_156945282_156945433	0.15	UBE3C	ubiquitin protein ligase E3C	13468	0.22
chr4_85602887_85603189	0.15	ENSG00000239466	.	6133	0.27
chr19_23437287_23437525	0.15	ZNF724P	zinc finger protein 724, pseudogene	4214	0.29
chr4_143172838_143172989	0.14	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	54072	0.19
chr19_18490843_18491034	0.14	GDF15	growth differentiation factor 15	2042	0.16
chr9_80539292_80539443	0.14	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	101452	0.08
chr8_8820590_8820741	0.14	ENSG00000207244	.	1580	0.39
chr3_43334090_43334357	0.14	SNRK	SNF related kinase	6145	0.2
chr15_68376694_68376845	0.14	PIAS1	protein inhibitor of activated STAT, 1	29855	0.22
chr18_9596078_9596229	0.14	RP11-881L2.1		8769	0.16
chrX_153265369_153265652	0.14	IRAK1	interleukin-1 receptor-associated kinase 1	14187	0.09
chr20_50108720_50109319	0.14	ENSG00000266761	.	39505	0.18
chr17_4262517_4262743	0.14	ENSG00000263882	.	5118	0.18
chr6_15381784_15381935	0.14	JARID2	jumonji, AT rich interactive domain 2	19230	0.22
chr8_102038362_102038931	0.14	ENSG00000252736	.	63375	0.1
chr16_69431934_69432085	0.14	TERF2	telomeric repeat binding factor 2	10465	0.13
chr3_42121230_42121496	0.14	TRAK1	trafficking protein, kinesin binding 1	11199	0.27
chr10_114854381_114854621	0.14	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	49178	0.18
chr5_64505728_64505879	0.14	ENSG00000207439	.	86607	0.1
chr2_112789798_112789949	0.14	MERTK	c-mer proto-oncogene tyrosine kinase	12883	0.21
chr9_4661316_4661551	0.14	PPAPDC2	phosphatidic acid phosphatase type 2 domain containing 2	865	0.57
chr17_60868423_60868627	0.14	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	15476	0.23
chr15_68177525_68177676	0.14	ENSG00000206625	.	45217	0.17
chr15_55881471_55881622	0.14	PYGO1	pygopus family PHD finger 1	401	0.89
chr2_43242041_43242192	0.14	ENSG00000207087	.	76516	0.11
chr8_18066990_18067251	0.14	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)	482	0.88
chr9_102682165_102682316	0.14	RP11-60I3.4		9938	0.18
chr17_39068896_39069135	0.14	AC004231.2		8667	0.1
chr15_71583507_71583658	0.14	RP11-592N21.2		51081	0.16
chr20_52353487_52354058	0.13	ENSG00000238468	.	68475	0.12
chr3_18468302_18468610	0.13	SATB1	SATB homeobox 1	1595	0.42
chr12_22486049_22486200	0.13	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	973	0.7
chr7_17976053_17976204	0.13	SNX13	sorting nexin 13	3963	0.31
chr1_70469306_70469482	0.13	RP11-181B18.1		18687	0.26
chr1_107598936_107599204	0.13	PRMT6	protein arginine methyltransferase 6	197	0.97
chr1_23668057_23668694	0.13	HNRNPR	heterogeneous nuclear ribonucleoprotein R	2380	0.23
chr5_55881573_55881982	0.13	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	20282	0.21
chr5_169577969_169578120	0.13	FOXI1	forkhead box I1	45127	0.16
chr13_31774982_31775836	0.13	B3GALTL	beta 1,3-galactosyltransferase-like	1336	0.55
chr10_82773983_82774134	0.13	ENSG00000265990	.	130350	0.06
chr1_53739428_53739681	0.13	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	1781	0.2
chr1_161122819_161122970	0.13	UFC1	ubiquitin-fold modifier conjugating enzyme 1	648	0.42
chr6_90868910_90869061	0.13	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	137476	0.04
chr7_5704858_5705042	0.13	RNF216-IT1	RNF216 intronic transcript 1 (non-protein coding)	15142	0.19
chr19_44087068_44087219	0.13	PINLYP	phospholipase A2 inhibitor and LY6/PLAUR domain containing	1954	0.14
chr1_51889386_51889537	0.13	EPS15	epidermal growth factor receptor pathway substrate 15	471	0.8
chr7_121170101_121170252	0.13	ENSG00000221690	.	44632	0.19
chr6_159571881_159572032	0.13	RP11-13P5.2		16429	0.19
chr18_7084430_7084600	0.13	RP11-76K13.3		7699	0.23
chr19_18575570_18575881	0.13	ELL	elongation factor RNA polymerase II	11018	0.1
chr9_124118304_124118517	0.13	STOM	stomatin	14073	0.14
chr2_219129032_219129405	0.13	AAMP	angio-associated, migratory cell protein	1586	0.21
chr17_61501531_61501682	0.13	RP11-269G24.3		6844	0.14
chr1_218633775_218633926	0.13	C1orf143	chromosome 1 open reading frame 143	49588	0.16
chr1_60391839_60392206	0.13	CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	440	0.87
chr9_20320271_20320422	0.13	ENSG00000221744	.	25344	0.21
chr6_7050238_7050389	0.13	ENSG00000251762	.	9534	0.25
chr12_54021012_54021163	0.13	ATF7	activating transcription factor 7	888	0.44
chr11_43757721_43758198	0.13	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	55628	0.13
chrX_48859192_48859344	0.13	GRIPAP1	GRIP1 associated protein 1	593	0.56
chr1_41178229_41178380	0.13	NFYC	nuclear transcription factor Y, gamma	3089	0.2
chr11_35251646_35251916	0.12	CD44	CD44 molecule (Indian blood group)	10890	0.15
chr1_172328500_172328837	0.12	ENSG00000206684	.	7012	0.18
chr15_90925903_90926054	0.12	IQGAP1	IQ motif containing GTPase activating protein 1	5472	0.15
chr2_2650026_2650177	0.12	MYT1L	myelin transcription factor 1-like	315135	0.01
chr20_19797225_19797376	0.12	AL121761.2	Uncharacterized protein	58621	0.12
chr2_48551769_48552030	0.12	FOXN2	forkhead box N2	10050	0.22
chr12_69894065_69894216	0.12	FRS2	fibroblast growth factor receptor substrate 2	29926	0.17
chr22_43559847_43560025	0.12	TTLL12	tubulin tyrosine ligase-like family, member 12	7820	0.14
chr1_83043773_83044235	0.12	LPHN2	latrophilin 2	598431	0.0
chr9_111874941_111875092	0.12	TMEM245	transmembrane protein 245	7209	0.2
chr1_172795013_172795164	0.12	FASLG	Fas ligand (TNF superfamily, member 6)	166930	0.03
chr2_61193206_61193983	0.12	ENSG00000222251	.	32293	0.14
chr15_83513364_83513515	0.12	HOMER2	homer homolog 2 (Drosophila)	5040	0.17
chr17_74259263_74259519	0.12	UBALD2	UBA-like domain containing 2	1892	0.24
chr2_25584992_25585274	0.12	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	19674	0.2
chr6_139090481_139090632	0.12	CCDC28A	coiled-coil domain containing 28A	4101	0.24
chr6_16737522_16738057	0.12	RP1-151F17.1		23580	0.22
chr20_56827001_56827171	0.12	PPP4R1L	protein phosphatase 4, regulatory subunit 1-like	264	0.93
chr5_158632936_158633295	0.12	RNF145	ring finger protein 145	1527	0.36
chr5_68798177_68798328	0.12	RP11-241G9.3		41	0.96
chr11_46130483_46130634	0.12	ENSG00000263539	.	4211	0.24
chr6_170596098_170596249	0.12	DLL1	delta-like 1 (Drosophila)	3388	0.21
chr7_32531022_32531199	0.12	LSM5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	1080	0.58
chr15_59642926_59643113	0.12	RP11-356M20.3		9069	0.13
chr6_2546230_2546381	0.12	C6orf195	chromosome 6 open reading frame 195	88532	0.09
chr10_116616195_116616346	0.12	FAM160B1	family with sequence similarity 160, member B1	4280	0.32
chr2_191583791_191583942	0.12	AC006460.2		10424	0.24
chr5_17235667_17236039	0.12	ENSG00000252908	.	4867	0.21
chr12_10794215_10794366	0.12	STYK1	serine/threonine/tyrosine kinase 1	12053	0.16
chr10_35231257_35231408	0.12	ENSG00000222909	.	565	0.79
chr9_132733431_132733683	0.12	FNBP1	formin binding protein 1	23589	0.17
chr4_88025923_88026419	0.12	AFF1	AF4/FMR2 family, member 1	55367	0.15
chr5_88047186_88047337	0.12	CTC-467M3.2		58793	0.12
chr15_71118836_71119061	0.12	RP11-138H8.6		23161	0.14
chr9_124706762_124707039	0.12	RP11-244O19.1		125169	0.05
chr9_128649834_128649985	0.12	PBX3	pre-B-cell leukemia homeobox 3	22359	0.27
chr1_186342452_186343004	0.12	TPR	translocated promoter region, nuclear basket protein	1729	0.26
chr1_173145333_173145484	0.12	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	29289	0.23
chr8_28570826_28570977	0.12	EXTL3	exostosin-like glycosyltransferase 3	3026	0.25
chr1_203653860_203654011	0.12	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	1998	0.36
chr2_208147717_208147868	0.12	ENSG00000221628	.	13644	0.22
chr7_70144187_70144338	0.12	AUTS2	autism susceptibility candidate 2	49863	0.2
chr3_171072744_171072895	0.12	ENSG00000222506	.	84496	0.09
chr6_116685228_116685657	0.12	DSE	dermatan sulfate epimerase	5568	0.22
chr9_37859453_37859604	0.12	SLC25A51	solute carrier family 25, member 51	29063	0.17
chr15_43781223_43781374	0.12	TP53BP1	tumor protein p53 binding protein 1	3986	0.18
chr22_41247543_41247694	0.12	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	2984	0.17
chr12_46949120_46949271	0.12	SLC38A2	solute carrier family 38, member 2	182545	0.03
chr7_25009452_25009603	0.12	OSBPL3	oxysterol binding protein-like 3	10233	0.27
chr3_141243275_141243445	0.12	RASA2-IT1	RASA2 intronic transcript 1 (non-protein coding)	615	0.79
chr11_32925473_32925624	0.12	QSER1	glutamine and serine rich 1	10824	0.23
chr18_21406136_21407050	0.12	LAMA3	laminin, alpha 3	7324	0.26
chr13_40260042_40260269	0.12	ENSG00000264171	.	21883	0.17
chr2_192138781_192138977	0.12	MYO1B	myosin IB	2732	0.37
chr14_89297995_89298146	0.11	TTC8	tetratricopeptide repeat domain 8	6987	0.18
chr3_130681680_130681831	0.11	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1	4477	0.2
chr7_17530312_17530463	0.11	ENSG00000199473	.	117437	0.06
chr5_88340644_88340795	0.11	MEF2C-AS1	MEF2C antisense RNA 1	79027	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.2	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0010523	negative regulation of calcium ion transport into cytosol(GO:0010523)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0030056	hemidesmosome(GO:0030056)
0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	GO:0071942	XPC complex(GO:0071942)
0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2	GO:0031528	microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	GO:0048156	tau protein binding(GO:0048156)
0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	GO:0043559	insulin binding(GO:0043559)
0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane