Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FOXO4

Z-value: 2.58

Motif logo

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Transcription factors associated with FOXO4

Gene Symbol Gene ID Gene Info
ENSG00000184481.12 FOXO4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
FOXO4chrX_70319202_7031947829610.143083-0.761.8e-02Click!
FOXO4chrX_70317352_7031771711550.325046-0.694.0e-02Click!
FOXO4chrX_70317746_7031796314750.253443-0.684.3e-02Click!
FOXO4chrX_70318458_7031885222760.171452-0.675.0e-02Click!
FOXO4chrX_70316780_703170055130.651915-0.637.1e-02Click!

Activity of the FOXO4 motif across conditions

Conditions sorted by the z-value of the FOXO4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_103838670_103838952 1.59 MARK3
MAP/microtubule affinity-regulating kinase 3
12918
0.15
chr10_73292337_73292498 1.47 CDH23-AS1
CDH23 antisense RNA 1
20787
0.22
chr3_187627904_187628178 1.05 BCL6
B-cell CLL/lymphoma 6
164526
0.04
chr5_52627609_52627883 1.03 FST
follistatin
148493
0.04
chr1_31870789_31870940 1.02 SERINC2
serine incorporator 2
11548
0.15
chr7_98717947_98718887 0.98 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
23225
0.2
chr15_46162513_46162674 0.96 SQRDL
sulfide quinone reductase-like (yeast)
187855
0.03
chr18_18743331_18743728 0.95 ENSG00000251886
.
43062
0.15
chr12_47353443_47353741 0.95 PCED1B
PC-esterase domain containing 1B
119794
0.06
chr1_161880198_161880487 0.94 OLFML2B
olfactomedin-like 2B
74680
0.09
chr2_39639595_39639746 0.93 ENSG00000252239
.
18911
0.17
chr4_157242892_157243172 0.92 ENSG00000221189
.
25234
0.27
chr6_73263572_73263723 0.92 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
67873
0.12
chr18_71983992_71984143 0.89 C18orf63
chromosome 18 open reading frame 63
1019
0.6
chr6_103680064_103680234 0.89 ENSG00000202283
.
350861
0.01
chr5_158267521_158267691 0.89 CTD-2363C16.1

142408
0.05
chrX_80831633_80831793 0.86 ENSG00000264374
.
335394
0.01
chr6_112204135_112204286 0.84 FYN
FYN oncogene related to SRC, FGR, YES
9555
0.29
chr18_32353571_32353898 0.84 RP11-138H11.1

6107
0.24
chr9_91268436_91268587 0.84 ENSG00000265873
.
92309
0.09
chr3_54925868_54926132 0.83 CACNA2D3-AS1
CACNA2D3 antisense RNA 1
9282
0.27
chr7_47521967_47522354 0.82 TNS3
tensin 3
1277
0.63
chr17_48137007_48137298 0.82 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
3348
0.18
chr15_99214048_99214893 0.80 IGF1R
insulin-like growth factor 1 receptor
22197
0.2
chr1_44950843_44951385 0.80 ENSG00000263381
.
60051
0.1
chr7_28078015_28078166 0.79 JAZF1
JAZF zinc finger 1
17672
0.25
chr4_119674096_119674247 0.79 SEC24D
SEC24 family member D
5626
0.29
chr4_55147977_55148291 0.79 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
38392
0.21
chr7_41046808_41047238 0.79 AC005160.3

231866
0.02
chr9_97855804_97855955 0.78 ENSG00000207617
.
7503
0.14
chr9_97567295_97567893 0.78 ENSG00000252153
.
4650
0.2
chr5_86453164_86453315 0.78 ENSG00000265919
.
42468
0.15
chr1_12483776_12483927 0.78 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
13927
0.23
chr10_104353007_104353158 0.77 ENSG00000207029
.
1801
0.32
chr9_94579747_94580327 0.76 ROR2
receptor tyrosine kinase-like orphan receptor 2
131125
0.05
chr15_63071438_63071589 0.76 ENSG00000265317
.
7493
0.19
chr14_51118154_51118305 0.75 SAV1
salvador homolog 1 (Drosophila)
6702
0.16
chr11_35121206_35121357 0.75 AL356215.1

28934
0.15
chr10_79669456_79669735 0.75 ENSG00000243446
.
2709
0.24
chr16_18943732_18943883 0.75 ENSG00000265515
.
2203
0.23
chr16_8818593_8818759 0.74 ABAT
4-aminobutyrate aminotransferase
4100
0.19
chr1_246038886_246039037 0.74 RP11-83A16.1

157892
0.04
chr6_128828935_128829086 0.74 RP1-86D1.4

2740
0.23
chr1_212841868_212842366 0.74 ENSG00000207491
.
23489
0.13
chr12_80580882_80581068 0.73 OTOGL
otogelin-like
22258
0.25
chr6_154609795_154609953 0.73 IPCEF1
interaction protein for cytohesin exchange factors 1
41058
0.21
chr5_153666507_153666707 0.73 ENSG00000221070
.
53079
0.12
chr17_59385442_59385593 0.73 RP11-332H18.3

74629
0.08
chr9_118403979_118404130 0.73 DEC1
deleted in esophageal cancer 1
499957
0.0
chr11_12147194_12147407 0.73 MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
4278
0.32
chr12_66089003_66089154 0.72 HMGA2
high mobility group AT-hook 2
128833
0.05
chr7_123687522_123687673 0.72 TMEM229A
transmembrane protein 229A
14074
0.2
chr7_54878481_54878866 0.72 SEC61G
Sec61 gamma subunit
51006
0.13
chr21_30873206_30873481 0.71 BACH1-IT3
BACH1 intronic transcript 3 (non-protein coding)
4976
0.28
chr9_22999786_22999941 0.71 ENSG00000265572
.
46761
0.21
chr12_12813557_12813849 0.71 GPR19
G protein-coupled receptor 19
23752
0.15
chr10_127836908_127837102 0.71 ENSG00000222740
.
2854
0.38
chr6_16738097_16738621 0.71 RP1-151F17.1

23010
0.22
chr13_109567579_109568598 0.70 MYO16
myosin XVI
29571
0.26
chr6_4126077_4126228 0.70 RP3-400B16.4

9505
0.16
chr1_115842528_115842679 0.70 RP4-663N10.1

16948
0.23
chr12_32269810_32269961 0.70 RP11-843B15.2

9423
0.23
chr16_24742094_24743166 0.70 TNRC6A
trinucleotide repeat containing 6A
1596
0.5
chr14_23549622_23550020 0.69 ACIN1
apoptotic chromatin condensation inducer 1
8995
0.09
chr15_75474383_75474534 0.69 C15orf39
chromosome 15 open reading frame 39
13526
0.13
chr13_114793174_114793325 0.69 RASA3
RAS p21 protein activator 3
50189
0.16
chr4_187857949_187858100 0.69 ENSG00000252382
.
79414
0.12
chr17_26673764_26673915 0.68 TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
6407
0.07
chr6_56573158_56573456 0.68 DST
dystonin
65513
0.14
chr10_30734331_30734677 0.68 MAP3K8
mitogen-activated protein kinase kinase kinase 8
6753
0.24
chr20_8841216_8841367 0.68 ENSG00000201348
.
29458
0.23
chr1_222341096_222341247 0.68 ENSG00000212094
.
154739
0.04
chr8_108467924_108468288 0.68 ANGPT1
angiopoietin 1
39117
0.23
chr19_13133727_13134698 0.68 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
593
0.58
chr3_151893804_151894059 0.67 MBNL1
muscleblind-like splicing regulator 1
91898
0.08
chr6_2433057_2433208 0.67 ENSG00000266252
.
23263
0.27
chr8_29034119_29034418 0.67 ENSG00000264328
.
34058
0.14
chr5_71448848_71449179 0.67 ENSG00000264099
.
16281
0.23
chr5_33120670_33120821 0.67 CTD-2203K17.1

319980
0.01
chr22_28627219_28627370 0.67 ENSG00000201209
.
1517
0.52
chr17_5749312_5749463 0.67 WSCD1
WSC domain containing 1
73141
0.12
chr7_134405371_134405522 0.67 CALD1
caldesmon 1
23557
0.23
chr18_60548793_60548944 0.67 PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
21515
0.2
chr12_6198255_6198797 0.66 ENSG00000240533
.
6610
0.23
chr11_108799819_108799970 0.66 ENSG00000201243
.
76350
0.12
chr2_192128890_192129041 0.66 MYO1B
myosin IB
666
0.8
chr1_172256096_172256397 0.65 ENSG00000252354
.
61037
0.11
chr1_95487323_95487474 0.65 RP11-313A24.1

39754
0.12
chr7_55177396_55177547 0.65 EGFR
epidermal growth factor receptor
55
0.99
chr14_92864210_92864675 0.65 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
10281
0.28
chr6_140784660_140784811 0.64 ENSG00000221336
.
197115
0.03
chr3_107763286_107763437 0.64 CD47
CD47 molecule
13847
0.3
chr4_96028568_96028719 0.64 BMPR1B
bone morphogenetic protein receptor, type IB
3137
0.41
chr1_95258755_95258906 0.64 SLC44A3
solute carrier family 44, member 3
27068
0.18
chr7_78159625_78159776 0.64 MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
240696
0.02
chr2_202663671_202663822 0.64 CDK15
cyclin-dependent kinase 15
7352
0.16
chr14_59213631_59214204 0.64 ENSG00000221427
.
24047
0.25
chr1_203372120_203372271 0.64 FMOD
fibromodulin
51578
0.12
chr19_3938704_3938855 0.64 NMRK2
nicotinamide riboside kinase 2
5174
0.11
chr1_234755566_234755985 0.63 IRF2BP2
interferon regulatory factor 2 binding protein 2
10504
0.19
chr6_57127553_57127704 0.63 RAB23
RAB23, member RAS oncogene family
40550
0.15
chr6_133967781_133967932 0.63 RP3-323P13.2

120890
0.06
chr5_17378288_17378589 0.63 ENSG00000201715
.
32713
0.22
chr16_70669255_70669406 0.63 IL34
interleukin 34
11138
0.15
chr2_151348832_151348983 0.63 RND3
Rho family GTPase 3
4664
0.37
chr4_95469001_95469152 0.63 PDLIM5
PDZ and LIM domain 5
24200
0.28
chr11_43757721_43758198 0.63 HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
55628
0.13
chr1_181047325_181047476 0.63 IER5
immediate early response 5
10238
0.21
chr3_172394693_172395213 0.62 ENSG00000264711
.
5524
0.18
chr18_9018366_9018517 0.62 NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
84187
0.08
chr3_159542532_159542683 0.62 ENSG00000264146
.
2123
0.28
chr4_129438611_129438957 0.62 PGRMC2
progesterone receptor membrane component 2
228800
0.02
chr12_42958679_42958830 0.62 PRICKLE1
prickle homolog 1 (Drosophila)
24724
0.21
chr14_74163695_74163846 0.62 RP4-693M11.3

3284
0.15
chr7_25886192_25886343 0.62 ENSG00000199085
.
103339
0.08
chr15_40793575_40793726 0.62 RP11-111A22.1

6573
0.11
chr16_59732879_59733030 0.62 RP11-105C20.2
Uncharacterized protein
55764
0.17
chr2_216392438_216392589 0.62 AC012462.1

91537
0.08
chr8_141001651_141001976 0.62 C8orf17
chromosome 8 open reading frame 17
58397
0.15
chr15_68817963_68818114 0.62 CORO2B
coronin, actin binding protein, 2B
53270
0.16
chr6_112548551_112548702 0.61 RP11-506B6.6

8668
0.18
chr4_9164846_9164997 0.61 ENSG00000264372
.
5099
0.13
chr7_137638967_137639212 0.61 AC022173.2

995
0.59
chr4_157882994_157883145 0.61 PDGFC
platelet derived growth factor C
8986
0.23
chr14_52133403_52133554 0.61 FRMD6
FERM domain containing 6
14780
0.18
chr5_143075483_143075634 0.61 ENSG00000266478
.
16133
0.26
chr12_66296267_66296535 0.61 RP11-366L20.2
Uncharacterized protein
20454
0.16
chr3_42225778_42226037 0.60 TRAK1
trafficking protein, kinesin binding 1
8662
0.23
chr7_148385490_148385641 0.60 CUL1
cullin 1
9441
0.19
chr1_201716780_201716931 0.60 NAV1
neuron navigator 1
7859
0.13
chr20_9389511_9389662 0.60 PLCB4
phospholipase C, beta 4
101139
0.07
chr6_111549262_111549413 0.60 RP11-428F8.2

30900
0.13
chr7_51102884_51103035 0.60 RP4-724E13.2

17799
0.27
chr16_49733508_49733659 0.60 ENSG00000221134
.
20452
0.22
chr2_9375414_9375688 0.60 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
28657
0.24
chr17_3774444_3774636 0.60 CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
19497
0.14
chr4_114358389_114358540 0.60 ENSG00000206820
.
16985
0.2
chr19_6745452_6745603 0.59 TRIP10
thyroid hormone receptor interactor 10
4598
0.13
chr13_31390730_31391089 0.59 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
81264
0.09
chr2_168048837_168048988 0.59 XIRP2
xin actin-binding repeat containing 2
5119
0.31
chr2_12959099_12960371 0.59 ENSG00000264370
.
82242
0.11
chr13_77089835_77089986 0.59 KCTD12
potassium channel tetramerization domain containing 12
370615
0.01
chr10_115086768_115086919 0.59 ENSG00000238380
.
26341
0.25
chr13_101045927_101046215 0.59 PCCA
propionyl CoA carboxylase, alpha polypeptide
25318
0.23
chr12_65954312_65954463 0.59 MSRB3
methionine sulfoxide reductase B3
233732
0.02
chr6_15627894_15628228 0.59 DTNBP1
dystrobrevin binding protein 1
35145
0.23
chr3_16132224_16132472 0.59 GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
83808
0.09
chr13_44819054_44819205 0.59 SMIM2
small integral membrane protein 2
83736
0.09
chr2_58108331_58108482 0.59 VRK2
vaccinia related kinase 2
26380
0.27
chr6_167011503_167011887 0.59 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
29030
0.2
chr2_46975949_46976336 0.58 SOCS5
suppressor of cytokine signaling 5
49816
0.11
chr11_114224456_114224725 0.58 RP11-64D24.2

2703
0.24
chr17_37895818_37896174 0.58 GRB7
growth factor receptor-bound protein 7
224
0.88
chr10_71206366_71206517 0.58 TSPAN15
tetraspanin 15
4788
0.23
chr4_1940825_1940976 0.58 WHSC1
Wolf-Hirschhorn syndrome candidate 1
488
0.77
chr2_43540037_43540188 0.58 AC010883.5

83400
0.09
chr3_125230252_125231290 0.58 ENSG00000201800
.
5052
0.18
chr18_63533544_63533695 0.58 RP11-389J22.1

1121
0.67
chr11_101988381_101988581 0.58 YAP1
Yes-associated protein 1
5236
0.19
chr8_93033119_93033344 0.58 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
1828
0.47
chr6_121843203_121843354 0.58 ENSG00000201379
.
20494
0.2
chr1_86034688_86034839 0.58 DDAH1
dimethylarginine dimethylaminohydrolase 1
9170
0.19
chr4_159794425_159794576 0.58 FNIP2
folliculin interacting protein 2
41268
0.16
chr2_19105426_19105685 0.57 NT5C1B
5'-nucleotidase, cytosolic IB
334717
0.01
chr14_31559795_31560006 0.57 AP4S1
adaptor-related protein complex 4, sigma 1 subunit
24398
0.15
chr9_80629523_80629733 0.57 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
15892
0.29
chr9_16626415_16626566 0.57 RP11-62F24.1

816
0.74
chr3_57015356_57015604 0.57 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
4077
0.27
chr11_57047746_57047897 0.57 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
41850
0.08
chr9_113597331_113597482 0.57 MUSK
muscle, skeletal, receptor tyrosine kinase
59779
0.13
chr4_114260120_114260271 0.57 ANK2
ankyrin 2, neuronal
2673
0.37
chr1_198859851_198860145 0.57 ENSG00000207759
.
31716
0.2
chr16_86686755_86687054 0.57 FOXL1
forkhead box L1
74789
0.1
chr13_24079029_24079180 0.57 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
65405
0.13
chr6_90994564_90995525 0.57 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
11417
0.24
chr11_9173045_9173196 0.57 DENND5A
DENN/MADD domain containing 5A
834
0.63
chr6_90694678_90695035 0.57 ENSG00000222078
.
16369
0.19
chr1_150501836_150501987 0.56 ADAMTSL4
ADAMTS-like 4
19973
0.08
chr12_68744532_68744683 0.56 MDM1
Mdm1 nuclear protein homolog (mouse)
18446
0.25
chr8_134029735_134030176 0.56 TG
thyroglobulin
11
0.98
chr3_190245134_190245536 0.56 IL1RAP
interleukin 1 receptor accessory protein
13444
0.26
chr2_40630418_40630569 0.56 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
26927
0.26
chr10_75646701_75646885 0.56 CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
12450
0.12
chr2_65589085_65589236 0.56 SPRED2
sprouty-related, EVH1 domain containing 2
4624
0.26
chr11_15989853_15990583 0.56 CTD-3096P4.1

54518
0.18
chr22_41050375_41050526 0.56 MKL1
megakaryoblastic leukemia (translocation) 1
17755
0.19
chr10_69854399_69854550 0.56 MYPN
myopalladin
11438
0.19
chr6_138876604_138876755 0.56 NHSL1
NHS-like 1
9831
0.27
chr5_88880300_88880451 0.56 MEF2C-AS1
MEF2C antisense RNA 1
165751
0.04
chr4_119890040_119890192 0.56 SYNPO2
synaptopodin 2
54510
0.16
chr4_177702748_177702899 0.56 VEGFC
vascular endothelial growth factor C
11058
0.3
chr18_479028_479179 0.56 COLEC12
collectin sub-family member 12
21619
0.18
chr1_67397953_67399117 0.55 MIER1
mesoderm induction early response 1, transcriptional regulator
2609
0.29
chr3_194892755_194893085 0.55 XXYLT1
xyloside xylosyltransferase 1
3482
0.19
chr12_26899774_26900056 0.55 ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
85799
0.09
chr3_59794708_59794859 0.55 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
162800
0.04
chr5_151063563_151063813 0.55 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
1103
0.43
chr13_24183429_24183829 0.55 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
30110
0.23
chr5_131550875_131551026 0.55 P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
6834
0.18
chr16_85547620_85547771 0.55 ENSG00000264203
.
72597
0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of FOXO4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070141 response to UV-A(GO:0070141)
0.2 0.4 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2 0.6 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.2 0.6 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 0.5 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.2 0.5 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.2 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 0.9 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.4 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.6 GO:0045056 transcytosis(GO:0045056)
0.1 0.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.5 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.3 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.6 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.3 GO:0010662 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 1.2 GO:0035329 hippo signaling(GO:0035329)
0.1 0.3 GO:0071436 sodium ion export(GO:0071436)
0.1 0.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.3 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.2 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0060004 reflex(GO:0060004)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.1 0.3 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.1 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.1 GO:0044851 hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0002634 regulation of germinal center formation(GO:0002634)
0.1 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.2 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0042640 anagen(GO:0042640)
0.1 0.3 GO:0031641 regulation of myelination(GO:0031641)
0.1 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 0.5 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.2 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.2 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.4 GO:0009629 response to gravity(GO:0009629)
0.0 0.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.9 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.3 GO:0060039 pericardium development(GO:0060039)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 1.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.2 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.3 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.5 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0060592 mammary gland formation(GO:0060592)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.3 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.7 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:1904063 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0042321 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.2 GO:0007494 midgut development(GO:0007494)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.6 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.2 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0002577 regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0061515 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.6 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.0 GO:2000846 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0036445 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.4 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.0 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.0 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.0 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.0 GO:0001840 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0043931 ossification involved in bone maturation(GO:0043931) organ maturation(GO:0048799) bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) bone maturation(GO:0070977)
0.0 0.0 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.6 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.0 0.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.0 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.0 GO:0072523 purine-containing compound catabolic process(GO:0072523)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.0 GO:0033598 mammary gland epithelial cell proliferation(GO:0033598)
0.0 0.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0043090 amino acid import(GO:0043090)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 0.0 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.0 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.5 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.1 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.7 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.6 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.4 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 2.9 GO:0030016 myofibril(GO:0030016)
0.0 0.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 1.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.0 GO:0005912 adherens junction(GO:0005912)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.9 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.7 GO:0042805 actinin binding(GO:0042805)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 1.0 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.5 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.5 GO:0048185 activin binding(GO:0048185)
0.1 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0004396 hexokinase activity(GO:0004396)
0.1 0.3 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.3 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0045502 dynein binding(GO:0045502)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0015368 calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.0 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.1 ST ADRENERGIC Adrenergic Pathway
0.1 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.2 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.1 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions