Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for FOXO4

Z-value: 2.58

Motif logo

Transcription factors associated with FOXO4

Gene Symbol	Gene ID	Gene Info
FOXO4 Ensembl NCBI GeneCards UniProt	ENSG00000184481.12	forkhead box O4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chrX_70319202_70319478	FOXO4	2961	0.143083	-0.76	1.8e-02	Click!
chrX_70317352_70317717	FOXO4	1155	0.325046	-0.69	4.0e-02	Click!
chrX_70317746_70317963	FOXO4	1475	0.253443	-0.68	4.3e-02	Click!
chrX_70318458_70318852	FOXO4	2276	0.171452	-0.67	5.0e-02	Click!
chrX_70316780_70317005	FOXO4	513	0.651915	-0.63	7.1e-02	Click!

Activity of the FOXO4 motif across conditions

Conditions sorted by the z-value of the FOXO4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_103838670_103838952	1.59	MARK3	MAP/microtubule affinity-regulating kinase 3	12918	0.15
chr10_73292337_73292498	1.47	CDH23-AS1	CDH23 antisense RNA 1	20787	0.22
chr3_187627904_187628178	1.05	BCL6	B-cell CLL/lymphoma 6	164526	0.04
chr5_52627609_52627883	1.03	FST	follistatin	148493	0.04
chr1_31870789_31870940	1.02	SERINC2	serine incorporator 2	11548	0.15
chr7_98717947_98718887	0.98	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	23225	0.2
chr15_46162513_46162674	0.96	SQRDL	sulfide quinone reductase-like (yeast)	187855	0.03
chr18_18743331_18743728	0.95	ENSG00000251886	.	43062	0.15
chr12_47353443_47353741	0.95	PCED1B	PC-esterase domain containing 1B	119794	0.06
chr1_161880198_161880487	0.94	OLFML2B	olfactomedin-like 2B	74680	0.09
chr2_39639595_39639746	0.93	ENSG00000252239	.	18911	0.17
chr4_157242892_157243172	0.92	ENSG00000221189	.	25234	0.27
chr6_73263572_73263723	0.92	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	67873	0.12
chr18_71983992_71984143	0.89	C18orf63	chromosome 18 open reading frame 63	1019	0.6
chr6_103680064_103680234	0.89	ENSG00000202283	.	350861	0.01
chr5_158267521_158267691	0.89	CTD-2363C16.1		142408	0.05
chrX_80831633_80831793	0.86	ENSG00000264374	.	335394	0.01
chr6_112204135_112204286	0.84	FYN	FYN oncogene related to SRC, FGR, YES	9555	0.29
chr18_32353571_32353898	0.84	RP11-138H11.1		6107	0.24
chr9_91268436_91268587	0.84	ENSG00000265873	.	92309	0.09
chr3_54925868_54926132	0.83	CACNA2D3-AS1	CACNA2D3 antisense RNA 1	9282	0.27
chr7_47521967_47522354	0.82	TNS3	tensin 3	1277	0.63
chr17_48137007_48137298	0.82	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	3348	0.18
chr15_99214048_99214893	0.80	IGF1R	insulin-like growth factor 1 receptor	22197	0.2
chr1_44950843_44951385	0.80	ENSG00000263381	.	60051	0.1
chr7_28078015_28078166	0.79	JAZF1	JAZF zinc finger 1	17672	0.25
chr4_119674096_119674247	0.79	SEC24D	SEC24 family member D	5626	0.29
chr4_55147977_55148291	0.79	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	38392	0.21
chr7_41046808_41047238	0.79	AC005160.3		231866	0.02
chr9_97855804_97855955	0.78	ENSG00000207617	.	7503	0.14
chr9_97567295_97567893	0.78	ENSG00000252153	.	4650	0.2
chr5_86453164_86453315	0.78	ENSG00000265919	.	42468	0.15
chr1_12483776_12483927	0.78	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	13927	0.23
chr10_104353007_104353158	0.77	ENSG00000207029	.	1801	0.32
chr9_94579747_94580327	0.76	ROR2	receptor tyrosine kinase-like orphan receptor 2	131125	0.05
chr15_63071438_63071589	0.76	ENSG00000265317	.	7493	0.19
chr14_51118154_51118305	0.75	SAV1	salvador homolog 1 (Drosophila)	6702	0.16
chr11_35121206_35121357	0.75	AL356215.1		28934	0.15
chr10_79669456_79669735	0.75	ENSG00000243446	.	2709	0.24
chr16_18943732_18943883	0.75	ENSG00000265515	.	2203	0.23
chr16_8818593_8818759	0.74	ABAT	4-aminobutyrate aminotransferase	4100	0.19
chr1_246038886_246039037	0.74	RP11-83A16.1		157892	0.04
chr6_128828935_128829086	0.74	RP1-86D1.4		2740	0.23
chr1_212841868_212842366	0.74	ENSG00000207491	.	23489	0.13
chr12_80580882_80581068	0.73	OTOGL	otogelin-like	22258	0.25
chr6_154609795_154609953	0.73	IPCEF1	interaction protein for cytohesin exchange factors 1	41058	0.21
chr5_153666507_153666707	0.73	ENSG00000221070	.	53079	0.12
chr17_59385442_59385593	0.73	RP11-332H18.3		74629	0.08
chr9_118403979_118404130	0.73	DEC1	deleted in esophageal cancer 1	499957	0.0
chr11_12147194_12147407	0.73	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	4278	0.32
chr12_66089003_66089154	0.72	HMGA2	high mobility group AT-hook 2	128833	0.05
chr7_123687522_123687673	0.72	TMEM229A	transmembrane protein 229A	14074	0.2
chr7_54878481_54878866	0.72	SEC61G	Sec61 gamma subunit	51006	0.13
chr21_30873206_30873481	0.71	BACH1-IT3	BACH1 intronic transcript 3 (non-protein coding)	4976	0.28
chr9_22999786_22999941	0.71	ENSG00000265572	.	46761	0.21
chr12_12813557_12813849	0.71	GPR19	G protein-coupled receptor 19	23752	0.15
chr10_127836908_127837102	0.71	ENSG00000222740	.	2854	0.38
chr6_16738097_16738621	0.71	RP1-151F17.1		23010	0.22
chr13_109567579_109568598	0.70	MYO16	myosin XVI	29571	0.26
chr6_4126077_4126228	0.70	RP3-400B16.4		9505	0.16
chr1_115842528_115842679	0.70	RP4-663N10.1		16948	0.23
chr12_32269810_32269961	0.70	RP11-843B15.2		9423	0.23
chr16_24742094_24743166	0.70	TNRC6A	trinucleotide repeat containing 6A	1596	0.5
chr14_23549622_23550020	0.69	ACIN1	apoptotic chromatin condensation inducer 1	8995	0.09
chr15_75474383_75474534	0.69	C15orf39	chromosome 15 open reading frame 39	13526	0.13
chr13_114793174_114793325	0.69	RASA3	RAS p21 protein activator 3	50189	0.16
chr4_187857949_187858100	0.69	ENSG00000252382	.	79414	0.12
chr17_26673764_26673915	0.68	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	6407	0.07
chr6_56573158_56573456	0.68	DST	dystonin	65513	0.14
chr10_30734331_30734677	0.68	MAP3K8	mitogen-activated protein kinase kinase kinase 8	6753	0.24
chr20_8841216_8841367	0.68	ENSG00000201348	.	29458	0.23
chr1_222341096_222341247	0.68	ENSG00000212094	.	154739	0.04
chr8_108467924_108468288	0.68	ANGPT1	angiopoietin 1	39117	0.23
chr19_13133727_13134698	0.68	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	593	0.58
chr3_151893804_151894059	0.67	MBNL1	muscleblind-like splicing regulator 1	91898	0.08
chr6_2433057_2433208	0.67	ENSG00000266252	.	23263	0.27
chr8_29034119_29034418	0.67	ENSG00000264328	.	34058	0.14
chr5_71448848_71449179	0.67	ENSG00000264099	.	16281	0.23
chr5_33120670_33120821	0.67	CTD-2203K17.1		319980	0.01
chr22_28627219_28627370	0.67	ENSG00000201209	.	1517	0.52
chr17_5749312_5749463	0.67	WSCD1	WSC domain containing 1	73141	0.12
chr7_134405371_134405522	0.67	CALD1	caldesmon 1	23557	0.23
chr18_60548793_60548944	0.67	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	21515	0.2
chr12_6198255_6198797	0.66	ENSG00000240533	.	6610	0.23
chr11_108799819_108799970	0.66	ENSG00000201243	.	76350	0.12
chr2_192128890_192129041	0.66	MYO1B	myosin IB	666	0.8
chr1_172256096_172256397	0.65	ENSG00000252354	.	61037	0.11
chr1_95487323_95487474	0.65	RP11-313A24.1		39754	0.12
chr7_55177396_55177547	0.65	EGFR	epidermal growth factor receptor	55	0.99
chr14_92864210_92864675	0.65	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	10281	0.28
chr6_140784660_140784811	0.64	ENSG00000221336	.	197115	0.03
chr3_107763286_107763437	0.64	CD47	CD47 molecule	13847	0.3
chr4_96028568_96028719	0.64	BMPR1B	bone morphogenetic protein receptor, type IB	3137	0.41
chr1_95258755_95258906	0.64	SLC44A3	solute carrier family 44, member 3	27068	0.18
chr7_78159625_78159776	0.64	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	240696	0.02
chr2_202663671_202663822	0.64	CDK15	cyclin-dependent kinase 15	7352	0.16
chr14_59213631_59214204	0.64	ENSG00000221427	.	24047	0.25
chr1_203372120_203372271	0.64	FMOD	fibromodulin	51578	0.12
chr19_3938704_3938855	0.64	NMRK2	nicotinamide riboside kinase 2	5174	0.11
chr1_234755566_234755985	0.63	IRF2BP2	interferon regulatory factor 2 binding protein 2	10504	0.19
chr6_57127553_57127704	0.63	RAB23	RAB23, member RAS oncogene family	40550	0.15
chr6_133967781_133967932	0.63	RP3-323P13.2		120890	0.06
chr5_17378288_17378589	0.63	ENSG00000201715	.	32713	0.22
chr16_70669255_70669406	0.63	IL34	interleukin 34	11138	0.15
chr2_151348832_151348983	0.63	RND3	Rho family GTPase 3	4664	0.37
chr4_95469001_95469152	0.63	PDLIM5	PDZ and LIM domain 5	24200	0.28
chr11_43757721_43758198	0.63	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	55628	0.13
chr1_181047325_181047476	0.63	IER5	immediate early response 5	10238	0.21
chr3_172394693_172395213	0.62	ENSG00000264711	.	5524	0.18
chr18_9018366_9018517	0.62	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	84187	0.08
chr3_159542532_159542683	0.62	ENSG00000264146	.	2123	0.28
chr4_129438611_129438957	0.62	PGRMC2	progesterone receptor membrane component 2	228800	0.02
chr12_42958679_42958830	0.62	PRICKLE1	prickle homolog 1 (Drosophila)	24724	0.21
chr14_74163695_74163846	0.62	RP4-693M11.3		3284	0.15
chr7_25886192_25886343	0.62	ENSG00000199085	.	103339	0.08
chr15_40793575_40793726	0.62	RP11-111A22.1		6573	0.11
chr16_59732879_59733030	0.62	RP11-105C20.2	Uncharacterized protein	55764	0.17
chr2_216392438_216392589	0.62	AC012462.1		91537	0.08
chr8_141001651_141001976	0.62	C8orf17	chromosome 8 open reading frame 17	58397	0.15
chr15_68817963_68818114	0.62	CORO2B	coronin, actin binding protein, 2B	53270	0.16
chr6_112548551_112548702	0.61	RP11-506B6.6		8668	0.18
chr4_9164846_9164997	0.61	ENSG00000264372	.	5099	0.13
chr7_137638967_137639212	0.61	AC022173.2		995	0.59
chr4_157882994_157883145	0.61	PDGFC	platelet derived growth factor C	8986	0.23
chr14_52133403_52133554	0.61	FRMD6	FERM domain containing 6	14780	0.18
chr5_143075483_143075634	0.61	ENSG00000266478	.	16133	0.26
chr12_66296267_66296535	0.61	RP11-366L20.2	Uncharacterized protein	20454	0.16
chr3_42225778_42226037	0.60	TRAK1	trafficking protein, kinesin binding 1	8662	0.23
chr7_148385490_148385641	0.60	CUL1	cullin 1	9441	0.19
chr1_201716780_201716931	0.60	NAV1	neuron navigator 1	7859	0.13
chr20_9389511_9389662	0.60	PLCB4	phospholipase C, beta 4	101139	0.07
chr6_111549262_111549413	0.60	RP11-428F8.2		30900	0.13
chr7_51102884_51103035	0.60	RP4-724E13.2		17799	0.27
chr16_49733508_49733659	0.60	ENSG00000221134	.	20452	0.22
chr2_9375414_9375688	0.60	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	28657	0.24
chr17_3774444_3774636	0.60	CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha	19497	0.14
chr4_114358389_114358540	0.60	ENSG00000206820	.	16985	0.2
chr19_6745452_6745603	0.59	TRIP10	thyroid hormone receptor interactor 10	4598	0.13
chr13_31390730_31391089	0.59	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	81264	0.09
chr2_168048837_168048988	0.59	XIRP2	xin actin-binding repeat containing 2	5119	0.31
chr2_12959099_12960371	0.59	ENSG00000264370	.	82242	0.11
chr13_77089835_77089986	0.59	KCTD12	potassium channel tetramerization domain containing 12	370615	0.01
chr10_115086768_115086919	0.59	ENSG00000238380	.	26341	0.25
chr13_101045927_101046215	0.59	PCCA	propionyl CoA carboxylase, alpha polypeptide	25318	0.23
chr12_65954312_65954463	0.59	MSRB3	methionine sulfoxide reductase B3	233732	0.02
chr6_15627894_15628228	0.59	DTNBP1	dystrobrevin binding protein 1	35145	0.23
chr3_16132224_16132472	0.59	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	83808	0.09
chr13_44819054_44819205	0.59	SMIM2	small integral membrane protein 2	83736	0.09
chr2_58108331_58108482	0.59	VRK2	vaccinia related kinase 2	26380	0.27
chr6_167011503_167011887	0.59	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	29030	0.2
chr2_46975949_46976336	0.58	SOCS5	suppressor of cytokine signaling 5	49816	0.11
chr11_114224456_114224725	0.58	RP11-64D24.2		2703	0.24
chr17_37895818_37896174	0.58	GRB7	growth factor receptor-bound protein 7	224	0.88
chr10_71206366_71206517	0.58	TSPAN15	tetraspanin 15	4788	0.23
chr4_1940825_1940976	0.58	WHSC1	Wolf-Hirschhorn syndrome candidate 1	488	0.77
chr2_43540037_43540188	0.58	AC010883.5		83400	0.09
chr3_125230252_125231290	0.58	ENSG00000201800	.	5052	0.18
chr18_63533544_63533695	0.58	RP11-389J22.1		1121	0.67
chr11_101988381_101988581	0.58	YAP1	Yes-associated protein 1	5236	0.19
chr8_93033119_93033344	0.58	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	1828	0.47
chr6_121843203_121843354	0.58	ENSG00000201379	.	20494	0.2
chr1_86034688_86034839	0.58	DDAH1	dimethylarginine dimethylaminohydrolase 1	9170	0.19
chr4_159794425_159794576	0.58	FNIP2	folliculin interacting protein 2	41268	0.16
chr2_19105426_19105685	0.57	NT5C1B	5'-nucleotidase, cytosolic IB	334717	0.01
chr14_31559795_31560006	0.57	AP4S1	adaptor-related protein complex 4, sigma 1 subunit	24398	0.15
chr9_80629523_80629733	0.57	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	15892	0.29
chr9_16626415_16626566	0.57	RP11-62F24.1		816	0.74
chr3_57015356_57015604	0.57	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	4077	0.27
chr11_57047746_57047897	0.57	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa	41850	0.08
chr9_113597331_113597482	0.57	MUSK	muscle, skeletal, receptor tyrosine kinase	59779	0.13
chr4_114260120_114260271	0.57	ANK2	ankyrin 2, neuronal	2673	0.37
chr1_198859851_198860145	0.57	ENSG00000207759	.	31716	0.2
chr16_86686755_86687054	0.57	FOXL1	forkhead box L1	74789	0.1
chr13_24079029_24079180	0.57	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	65405	0.13
chr6_90994564_90995525	0.57	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	11417	0.24
chr11_9173045_9173196	0.57	DENND5A	DENN/MADD domain containing 5A	834	0.63
chr6_90694678_90695035	0.57	ENSG00000222078	.	16369	0.19
chr1_150501836_150501987	0.56	ADAMTSL4	ADAMTS-like 4	19973	0.08
chr12_68744532_68744683	0.56	MDM1	Mdm1 nuclear protein homolog (mouse)	18446	0.25
chr8_134029735_134030176	0.56	TG	thyroglobulin	11	0.98
chr3_190245134_190245536	0.56	IL1RAP	interleukin 1 receptor accessory protein	13444	0.26
chr2_40630418_40630569	0.56	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	26927	0.26
chr10_75646701_75646885	0.56	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	12450	0.12
chr2_65589085_65589236	0.56	SPRED2	sprouty-related, EVH1 domain containing 2	4624	0.26
chr11_15989853_15990583	0.56	CTD-3096P4.1		54518	0.18
chr22_41050375_41050526	0.56	MKL1	megakaryoblastic leukemia (translocation) 1	17755	0.19
chr10_69854399_69854550	0.56	MYPN	myopalladin	11438	0.19
chr6_138876604_138876755	0.56	NHSL1	NHS-like 1	9831	0.27
chr5_88880300_88880451	0.56	MEF2C-AS1	MEF2C antisense RNA 1	165751	0.04
chr4_119890040_119890192	0.56	SYNPO2	synaptopodin 2	54510	0.16
chr4_177702748_177702899	0.56	VEGFC	vascular endothelial growth factor C	11058	0.3
chr18_479028_479179	0.56	COLEC12	collectin sub-family member 12	21619	0.18
chr1_67397953_67399117	0.55	MIER1	mesoderm induction early response 1, transcriptional regulator	2609	0.29
chr3_194892755_194893085	0.55	XXYLT1	xyloside xylosyltransferase 1	3482	0.19
chr12_26899774_26900056	0.55	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	85799	0.09
chr3_59794708_59794859	0.55	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	162800	0.04
chr5_151063563_151063813	0.55	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	1103	0.43
chr13_24183429_24183829	0.55	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	30110	0.23
chr5_131550875_131551026	0.55	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	6834	0.18
chr16_85547620_85547771	0.55	ENSG00000264203	.	72597	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0070141	response to UV-A(GO:0070141)
0.2	0.4	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2	0.6	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.2	0.6	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2	0.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.2	GO:0030011	maintenance of cell polarity(GO:0030011)
0.2	0.5	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.2	0.5	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.2	0.5	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.2	0.9	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.4	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.6	GO:0045056	transcytosis(GO:0045056)
0.1	0.9	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.4	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.6	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.4	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.5	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.5	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.3	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	0.3	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.6	GO:0001553	luteinization(GO:0001553)
0.1	0.4	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.5	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.5	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.3	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.4	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.4	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.3	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	1.2	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.7	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.3	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1	0.2	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.5	GO:0060004	reflex(GO:0060004)
0.1	0.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.3	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.1	GO:0044851	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.1	0.4	GO:0006477	protein sulfation(GO:0006477)
0.1	0.4	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0042640	anagen(GO:0042640)
0.1	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.1	0.5	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	0.2	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.8	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.2	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.1	0.2	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.4	GO:0009629	response to gravity(GO:0009629)
0.0	0.6	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.9	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.3	GO:0060039	pericardium development(GO:0060039)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	1.2	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.2	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.2	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.3	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.3	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.5	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.4	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.3	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.8	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.7	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:1904063	negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0031529	ruffle organization(GO:0031529)
0.0	0.2	GO:0007494	midgut development(GO:0007494)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.3	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.6	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.4	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.2	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.2	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.0	GO:0002577	regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.2	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.0	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.2	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0042762	regulation of sulfur metabolic process(GO:0042762)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.6	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.0	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.0	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0034391	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	0.3	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0036445	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.4	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.1	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.0	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.0	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.4	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.0	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0060479	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.0	GO:0001840	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0043931	ossification involved in bone maturation(GO:0043931) organ maturation(GO:0048799) bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) bone maturation(GO:0070977)
0.0	0.0	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.2	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.6	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0048841	regulation of axon extension involved in axon guidance(GO:0048841)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0031034	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.3	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.0	GO:0072523	purine-containing compound catabolic process(GO:0072523)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0045026	plasma membrane fusion(GO:0045026)
0.0	0.0	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.0	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0043090	amino acid import(GO:0043090)
0.0	0.0	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.0	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0014014	negative regulation of gliogenesis(GO:0014014)
0.0	0.0	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0060444	branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0	0.0	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.2	1.0	GO:0016342	catenin complex(GO:0016342)
0.1	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	1.0	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.3	GO:0033643	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.7	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.3	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.6	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.5	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	1.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.5	GO:0030315	T-tubule(GO:0030315)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	2.9	GO:0030016	myofibril(GO:0030016)
0.0	0.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	1.0	GO:0016459	myosin complex(GO:0016459)
0.0	0.6	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	4.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.9	GO:0030426	growth cone(GO:0030426)
0.0	1.2	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.3	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	1.1	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	1.0	GO:0005912	adherens junction(GO:0005912)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.6	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	0.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.9	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.7	GO:0042805	actinin binding(GO:0042805)
0.2	0.6	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	1.0	GO:0030507	spectrin binding(GO:0030507)
0.1	0.4	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	1.0	GO:0017166	vinculin binding(GO:0017166)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.7	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	1.0	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.6	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.6	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.3	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.6	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.3	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	0.8	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.4	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.5	GO:0005112	Notch binding(GO:0005112)
0.1	0.4	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	1.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.5	GO:0048185	activin binding(GO:0048185)
0.1	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0004396	hexokinase activity(GO:0004396)
0.1	0.3	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.6	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.5	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.4	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.3	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.5	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	2.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.3	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0015368	calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.9	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.4	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.0	GO:0005549	odorant binding(GO:0005549)
0.0	0.0	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.1	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	1.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.1	ST ADRENERGIC	Adrenergic Pathway
0.1	1.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	3.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.7	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	3.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.6	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.2	1.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	2.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.1	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1	0.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.8	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	2.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions

Results for FOXO4

Z-value: 2.58

Motif logo

Transcription factors associated with FOXO4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the FOXO4 motif across conditions

Conditions sorted by the z-value of the FOXO4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO4

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: