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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for FUBP1

Z-value: 1.30

Motif logo

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Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
FUBP1
ENSG00000162613.12 far upstream element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_78416310_78416461FUBP1283600.127943-0.732.7e-02Click!
chr1_78439235_78439436FUBP154100.170768-0.571.1e-01Click!
chr1_78440457_78440608FUBP142130.181598-0.481.9e-01Click!
chr1_78416706_78416961FUBP1279120.128766-0.462.1e-01Click!
chr1_78436297_78436448FUBP183730.159883-0.432.5e-01Click!

Activity of the FUBP1 motif across conditions

Conditions sorted by the z-value of the FUBP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_98717947_98718887 0.36 SMURF1
 SMAD specific E3 ubiquitin protein ligase 1
 23225
 0.2
chr14_70180420_70180571 0.33 SRSF5
 serine/arginine-rich splicing factor 5
 13122
 0.24
chr3_50410474_50410625 0.31 XXcos-LUCA11.4
5653
 0.09
chr16_30066961_30067112 0.31 ALDOA
 aldolase A, fructose-bisphosphate
 2581
 0.11
chr3_107763286_107763437 0.30 CD47
 CD47 molecule
 13847
 0.3
chr2_191513228_191513379 0.29 NAB1
 NGFI-A binding protein 1 (EGR1 binding protein 1)
 318
 0.91
chr21_46312526_46312824 0.29 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 17870
 0.1
chr14_98622440_98622591 0.28 ENSG00000222066
 .
 175572
 0.03
chr12_111178547_111179341 0.28 PPP1CC
 protein phosphatase 1, catalytic subunit, gamma isozyme
 1700
 0.39
chr12_118768131_118768393 0.27 TAOK3
 TAO kinase 3
 28648
 0.21
chr6_103680064_103680234 0.27 ENSG00000202283
 .
 350861
 0.01
chr8_142231323_142231474 0.27 SLC45A4
 solute carrier family 45, member 4
 7271
 0.16
chr19_10731127_10731278 0.27 SLC44A2
 solute carrier family 44 (choline transporter), member 2
 4732
 0.12
chr6_119618545_119618696 0.26 ENSG00000200732
 .
 29826
 0.21
chr1_40512120_40512273 0.26 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
 5642
 0.2
chr21_16592051_16592291 0.26 NRIP1
 nuclear receptor interacting protein 1
 154850
 0.04
chr8_101227636_101227787 0.26 ENSG00000199667
 .
 30345
 0.14
chrX_48859192_48859344 0.26 GRIPAP1
 GRIP1 associated protein 1
 593
 0.56
chr8_33412460_33412753 0.25 RNF122
 ring finger protein 122
 12037
 0.13
chr16_8818593_8818759 0.25 ABAT
 4-aminobutyrate aminotransferase
 4100
 0.19
chr5_133387222_133387373 0.24 VDAC1
 voltage-dependent anion channel 1
 46473
 0.14
chr15_91859349_91859500 0.24 SV2B
 synaptic vesicle glycoprotein 2B
 90324
 0.09
chr19_16695114_16695265 0.24 MED26
 mediator complex subunit 26
 3223
 0.11
chr10_33798752_33798923 0.24 NRP1
 neuropilin 1
 173647
 0.03
chr17_65420745_65420896 0.24 ENSG00000201547
 .
 15823
 0.13
chrX_128756598_128756859 0.24 APLN
 apelin
 26014
 0.21
chr1_205599149_205600013 0.23 ELK4
 ELK4, ETS-domain protein (SRF accessory protein 1)
 1509
 0.35
chrX_129254186_129254397 0.23 ELF4
 E74-like factor 4 (ets domain transcription factor)
 9600
 0.2
chr8_66588910_66589255 0.23 MTFR1
 mitochondrial fission regulator 1
 6866
 0.22
chr12_93984747_93985062 0.23 SOCS2
 suppressor of cytokine signaling 2
 16070
 0.18
chr6_14123211_14123362 0.23 CD83
 CD83 molecule
 5414
 0.28
chr13_41929051_41929202 0.23 ENSG00000223280
 .
 331
 0.89
chr19_16258305_16258456 0.23 HSH2D
 hematopoietic SH2 domain containing
 3834
 0.15
chr2_174818495_174818646 0.23 SP3
 Sp3 transcription factor
 10377
 0.31
chr5_40685914_40686124 0.23 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
 6419
 0.22
chrX_109275548_109275699 0.23 ENSG00000208013
 .
 22934
 0.19
chr22_38795449_38796163 0.23 CSNK1E
 casein kinase 1, epsilon
 1279
 0.34
chr10_22540840_22540991 0.23 EBLN1
 endogenous Bornavirus-like nucleoprotein 1
 41965
 0.14
chr12_122898532_122898723 0.22 CLIP1
 CAP-GLY domain containing linker protein 1
 8489
 0.22
chr15_46162513_46162674 0.22 SQRDL
 sulfide quinone reductase-like (yeast)
 187855
 0.03
chr1_204553065_204553216 0.22 RP11-430C7.4
19023
 0.14
chr3_31975446_31975713 0.22 OSBPL10
 oxysterol binding protein-like 10
 47213
 0.14
chr1_83043773_83044235 0.22 LPHN2
 latrophilin 2
 598431
 0.0
chr20_58562413_58562564 0.22 CDH26
 cadherin 26
 1673
 0.38
chr12_54672984_54673135 0.22 CBX5
 chromobox homolog 5
 827
 0.29
chr3_182534933_182535084 0.21 ATP11B
 ATPase, class VI, type 11B
 19897
 0.21
chr16_78534160_78534433 0.21 RP11-264L1.4
6169
 0.28
chr12_24893513_24893767 0.21 ENSG00000240481
 .
 33918
 0.21
chr19_47820020_47820171 0.21 C5AR1
 complement component 5a receptor 1
 6964
 0.14
chr1_100817300_100817579 0.21 CDC14A
 cell division cycle 14A
 149
 0.96
chr15_50346989_50347245 0.21 ATP8B4
 ATPase, class I, type 8B, member 4
 7533
 0.26
chr1_100819282_100819607 0.21 CDC14A
 cell division cycle 14A
 939
 0.57
chr17_79371033_79371247 0.21 RP11-1055B8.6
 Uncharacterized protein
 1865
 0.2
chr5_148927186_148927463 0.21 CSNK1A1
 casein kinase 1, alpha 1
 2538
 0.24
chr2_201980395_201980546 0.21 CFLAR
 CASP8 and FADD-like apoptosis regulator
 357
 0.82
chr9_136933917_136934117 0.21 BRD3
 bromodomain containing 3
 360
 0.86
chr2_161289913_161290064 0.21 RBMS1
 RNA binding motif, single stranded interacting protein 1
 17299
 0.2
chr5_158267521_158267691 0.20 CTD-2363C16.1
142408
 0.05
chr2_234474872_234475097 0.20 USP40
 ubiquitin specific peptidase 40
 396
 0.86
chr21_36260768_36260938 0.20 RUNX1
 runt-related transcription factor 1
 134
 0.98
chr12_57077760_57078152 0.20 PTGES3
 prostaglandin E synthase 3 (cytosolic)
 3990
 0.14
chr1_45668899_45669050 0.20 ZSWIM5
 zinc finger, SWIM-type containing 5
 3254
 0.26
chr4_86655280_86655719 0.20 ENSG00000266421
 .
 11878
 0.26
chr21_47887630_47887781 0.20 DIP2A-IT1
 DIP2A intronic transcript 1 (non-protein coding)
 5321
 0.17
chr5_37346370_37346521 0.20 ENSG00000251880
 .
 19208
 0.18
chr20_62543850_62544001 0.20 ENSG00000199805
 .
 3617
 0.09
chr9_123960312_123961002 0.20 RAB14
 RAB14, member RAS oncogene family
 3490
 0.19
chr9_91047692_91047843 0.20 SPIN1
 spindlin 1
 44421
 0.17
chr9_100926805_100927131 0.20 CORO2A
 coronin, actin binding protein, 2A
 8198
 0.21
chr18_76738214_76738365 0.20 SALL3
 spalt-like transcription factor 3
 1986
 0.46
chr3_119806632_119806783 0.20 GSK3B
 glycogen synthase kinase 3 beta
 5806
 0.22
chr3_71751243_71751726 0.20 EIF4E3
 eukaryotic translation initiation factor 4E family member 3
 23042
 0.2
chr15_99398269_99398432 0.20 IGF1R
 insulin-like growth factor 1 receptor
 35220
 0.16
chr5_138638673_138638824 0.20 ENSG00000199545
 .
 3207
 0.14
chr19_37339471_37339622 0.19 ZNF790
 zinc finger protein 790
 1669
 0.24
chr16_12910804_12910955 0.19 CPPED1
 calcineurin-like phosphoesterase domain containing 1
 13005
 0.18
chrX_15448302_15448453 0.19 BMX
 BMX non-receptor tyrosine kinase
 33992
 0.15
chr18_59856200_59856529 0.19 KIAA1468
 KIAA1468
 1840
 0.31
chr2_101946080_101946252 0.19 ENSG00000264857
 .
 20254
 0.16
chr4_48374879_48375030 0.19 SLAIN2
 SLAIN motif family, member 2
 4964
 0.28
chr19_915577_915728 0.19 KISS1R
 KISS1 receptor
 1635
 0.17
chr15_69866363_69866514 0.19 ENSG00000207119
 .
 115950
 0.05
chr12_120884573_120884899 0.19 GATC
 glutamyl-tRNA(Gln) amidotransferase, subunit C
 356
 0.55
chr16_87767946_87768097 0.19 RP11-278A23.2
13291
 0.16
chr13_28493501_28493652 0.19 PDX1
 pancreatic and duodenal homeobox 1
 581
 0.66
chr3_47170891_47171128 0.19 SETD2
 SET domain containing 2
 34057
 0.13
chr1_145661139_145661290 0.19 CD160
 CD160 molecule
 45647
 0.09
chr19_19539763_19539914 0.19 GATAD2A
 GATA zinc finger domain containing 2A
 1502
 0.3
chr5_132288576_132288727 0.19 ENSG00000202417
 .
 7617
 0.15
chr4_103741710_103742196 0.19 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
 4746
 0.17
chr14_23386672_23386823 0.19 RBM23
 RNA binding motif protein 23
 18
 0.93
chrX_38661555_38661850 0.18 MID1IP1
 MID1 interacting protein 1
 995
 0.5
chr1_19794748_19794899 0.18 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 15756
 0.16
chr14_69401611_69401762 0.18 ACTN1
 actinin, alpha 1
 12579
 0.23
chr3_186674135_186674286 0.18 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 18535
 0.2
chr12_40627003_40627154 0.18 LRRK2
 leucine-rich repeat kinase 2
 8202
 0.24
chr19_1907912_1908063 0.18 ADAT3
 adenosine deaminase, tRNA-specific 3
 31
 0.78
chr13_33199531_33199682 0.18 PDS5B
 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
 39042
 0.19
chr10_115615104_115615263 0.18 NHLRC2
 NHL repeat containing 2
 763
 0.48
chr6_111790354_111790505 0.18 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
 13985
 0.19
chr9_139158921_139159104 0.18 QSOX2
 quiescin Q6 sulfhydryl oxidase 2
 21325
 0.15
chr10_12632571_12632722 0.18 ENSG00000263584
 .
 11894
 0.27
chrX_44884110_44884261 0.18 KDM6A
 lysine (K)-specific demethylase 6A
 34342
 0.22
chr16_84413717_84413987 0.18 ATP2C2
 ATPase, Ca++ transporting, type 2C, member 2
 11719
 0.19
chrX_119597210_119597803 0.18 LAMP2
 lysosomal-associated membrane protein 2
 5341
 0.25
chr19_50934673_50934858 0.18 MYBPC2
 myosin binding protein C, fast type
 1395
 0.23
chr1_151196545_151196783 0.18 PIP5K1A
 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
 10257
 0.1
chr2_134935532_134935768 0.18 ENSG00000263813
 .
 50954
 0.14
chr13_48799322_48799473 0.18 ITM2B
 integral membrane protein 2B
 7897
 0.27
chr12_111807867_111808018 0.18 FAM109A
 family with sequence similarity 109, member A
 1017
 0.54
chr2_228362313_228362464 0.18 AGFG1
 ArfGAP with FG repeats 1
 10600
 0.21
chr1_27577181_27577392 0.18 ENSG00000252098
 .
 4772
 0.16
chr3_188390892_188391164 0.18 ENSG00000207651
 .
 15541
 0.22
chr11_1544049_1544200 0.18 MOB2
 MOB kinase activator 2
 36148
 0.1
chr1_171705490_171705830 0.18 VAMP4
 vesicle-associated membrane protein 4
 5542
 0.2
chr3_48477048_48477199 0.18 CCDC51
 coiled-coil domain containing 51
 2505
 0.13
chr7_101708245_101708396 0.18 CTA-357J21.1
32017
 0.19
chr5_43019074_43019523 0.18 CTD-2201E18.3
385
 0.66
chr13_30158034_30158185 0.18 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 2820
 0.39
chr2_182760548_182760802 0.18 SSFA2
 sperm specific antigen 2
 3752
 0.25
chr2_12959099_12960371 0.17 ENSG00000264370
 .
 82242
 0.11
chr3_141045502_141045653 0.17 ZBTB38
 zinc finger and BTB domain containing 38
 2522
 0.33
chr8_121738828_121738979 0.17 RP11-713M15.1
34590
 0.2
chr7_157679283_157679434 0.17 RP11-452C13.1
18128
 0.22
chr20_34327925_34328154 0.17 RBM39
 RNA binding motif protein 39
 720
 0.55
chr5_55964707_55964858 0.17 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 62723
 0.12
chr7_76851520_76851672 0.17 FGL2
 fibrinogen-like 2
 22453
 0.19
chr12_66698497_66698648 0.17 HELB
 helicase (DNA) B
 2247
 0.27
chr14_45627397_45627548 0.17 FANCM
 Fanconi anemia, complementation group M
 3510
 0.21
chr7_129500510_129500817 0.17 ENSG00000207691
 .
 85809
 0.06
chr13_114119819_114119970 0.17 DCUN1D2-AS
 DCUN1D2 antisense RNA
 3322
 0.17
chr22_41683317_41683468 0.17 RANGAP1
 Ran GTPase activating protein 1
 1137
 0.35
chrX_44926778_44926929 0.17 KDM6A
 lysine (K)-specific demethylase 6A
 7551
 0.3
chr17_1082165_1082334 0.17 ABR
 active BCR-related
 829
 0.6
chr1_43411413_43411601 0.17 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 12993
 0.18
chr15_67356770_67357118 0.17 SMAD3
 SMAD family member 3
 843
 0.73
chr22_19073574_19073725 0.17 AC004471.9
35393
 0.09
chr12_10368361_10368512 0.17 RP11-656E20.5
1076
 0.38
chr3_16490080_16490231 0.17 RFTN1
 raftlin, lipid raft linker 1
 34217
 0.19
chr4_15681074_15681472 0.17 FBXL5
 F-box and leucine-rich repeat protein 5
 1904
 0.29
chr7_19155357_19155508 0.17 TWIST1
 twist family bHLH transcription factor 1
 1863
 0.27
chr4_143325972_143326254 0.17 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 26299
 0.28
chr19_46066687_46066838 0.17 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
 21315
 0.1
chr11_75380064_75380270 0.17 MAP6
 microtubule-associated protein 6
 2
 0.97
chr2_216993992_216994143 0.17 XRCC5
 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 19993
 0.19
chr15_63802358_63803207 0.17 USP3
 ubiquitin specific peptidase 3
 4863
 0.26
chr12_65091539_65091893 0.17 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 1387
 0.36
chr4_110512749_110512900 0.17 CCDC109B
 coiled-coil domain containing 109B
 30678
 0.18
chr22_40584317_40584468 0.17 TNRC6B
 trinucleotide repeat containing 6B
 10446
 0.26
chr12_69727071_69727222 0.17 LYZ
 lysozyme
 14975
 0.17
chr3_45053532_45053683 0.17 CLEC3B
 C-type lectin domain family 3, member B
 14068
 0.15
chrY_7035946_7036097 0.17 PRKY
 protein kinase, Y-linked, pseudogene
 106315
 0.07
chr6_119214221_119214767 0.17 ASF1A
 anti-silencing function 1A histone chaperone
 890
 0.63
chr17_65825111_65825409 0.16 BPTF
 bromodomain PHD finger transcription factor
 3002
 0.23
chr3_9797020_9797171 0.16 OGG1
 8-oxoguanine DNA glycosylase
 3508
 0.13
chr17_54678795_54679086 0.16 NOG
 noggin
 7880
 0.31
chr8_67526501_67526877 0.16 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 1160
 0.46
chrX_131172208_131172403 0.16 MST4
 Serine/threonine-protein kinase MST4
 14669
 0.21
chr4_84035931_84036357 0.16 PLAC8
 placenta-specific 8
 189
 0.96
chr6_137579705_137579856 0.16 IFNGR1
 interferon gamma receptor 1
 39194
 0.19
chr6_156709882_156710033 0.16 ENSG00000212295
 .
 10073
 0.33
chr6_149081739_149081986 0.16 UST
 uronyl-2-sulfotransferase
 13398
 0.3
chr15_86077549_86077700 0.16 AKAP13
 A kinase (PRKA) anchor protein 13
 9647
 0.21
chr15_77702308_77702459 0.16 PEAK1
 pseudopodium-enriched atypical kinase 1
 10059
 0.23
chr20_48321244_48321782 0.16 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 8902
 0.19
chr22_42632196_42632347 0.16 TCF20
 transcription factor 20 (AR1)
 20823
 0.18
chr8_42913895_42914749 0.16 FNTA
 farnesyltransferase, CAAX box, alpha
 227
 0.91
chr12_56609980_56610131 0.16 RNF41
 ring finger protein 41
 5430
 0.07
chr9_89562820_89562971 0.16 GAS1
 growth arrest-specific 1
 791
 0.79
chr9_20398844_20399100 0.16 ENSG00000263790
 .
 12264
 0.18
chr11_73468535_73468693 0.16 RAB6A
 RAB6A, member RAS oncogene family
 2524
 0.21
chr6_12608393_12608818 0.16 PHACTR1
 phosphatase and actin regulator 1
 109288
 0.07
chr15_92414828_92415014 0.16 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 17570
 0.25
chr11_64529641_64529792 0.16 PYGM
 phosphorylase, glycogen, muscle
 1947
 0.21
chr2_101188537_101188688 0.16 PDCL3
 phosducin-like 3
 3195
 0.21
chr20_3996709_3996860 0.16 RNF24
 ring finger protein 24
 555
 0.8
chr2_62702609_62702952 0.16 ENSG00000241625
 .
 15533
 0.23
chr9_135249138_135249289 0.16 SETX
 senataxin
 18841
 0.17
chr12_31470259_31470509 0.16 FAM60A
 family with sequence similarity 60, member A
 6712
 0.16
chr21_43149115_43149266 0.16 AP001615.9
10343
 0.18
chr2_68999011_68999272 0.16 ARHGAP25
 Rho GTPase activating protein 25
 2792
 0.33
chr17_49305755_49305970 0.16 MBTD1
 mbt domain containing 1
 3277
 0.21
chr4_169752762_169753076 0.16 PALLD
 palladin, cytoskeletal associated protein
 237
 0.89
chr16_14399831_14399982 0.16 ENSG00000207639
 .
 2082
 0.29
chr7_27190679_27190886 0.16 HOXA-AS3
 HOXA cluster antisense RNA 3
 1111
 0.21
chrX_47929101_47929252 0.16 ZNF630
 zinc finger protein 630
 1307
 0.34
chr19_35758705_35758856 0.16 USF2
 upstream transcription factor 2, c-fos interacting
 1101
 0.29
chr7_99739342_99739544 0.16 LAMTOR4
 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
 7087
 0.06
chr11_95781083_95781234 0.15 MTMR2
 myotubularin related protein 2
 123699
 0.06
chr5_72252681_72252978 0.15 FCHO2
 FCH domain only 2
 931
 0.64
chr10_131129546_131129832 0.15 MGMT
 O-6-methylguanine-DNA methyltransferase
 135759
 0.05
chr15_93062736_93063031 0.15 C15orf32
 chromosome 15 open reading frame 32
 47732
 0.15
chr2_38595705_38595856 0.15 ATL2
 atlastin GTPase 2
 7586
 0.3
chr21_45079176_45079327 0.15 HSF2BP
 heat shock transcription factor 2 binding protein
 100
 0.62
chr17_38684308_38684459 0.15 TNS4
 tensin 4
 26534
 0.13
chr21_16582150_16582301 0.15 NRIP1
 nuclear receptor interacting protein 1
 144904
 0.05
chr12_77165937_77166088 0.15 ZDHHC17
 zinc finger, DHHC-type containing 17
 7659
 0.3
chr11_117199148_117199640 0.15 CEP164
 centrosomal protein 164kDa
 575
 0.46
chr1_53739428_53739681 0.15 LRP8
 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
 1781
 0.2
chr11_35061219_35061445 0.15 PDHX
 pyruvate dehydrogenase complex, component X
 62001
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.3 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:2000051 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0060912 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 0.1 GO:0031529 ruffle organization(GO:0031529)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.0 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.0 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.0 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0031943 regulation of glucocorticoid metabolic process(GO:0031943)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0070193 synaptonemal complex organization(GO:0070193)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0044217 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0097525 spliceosomal snRNP complex(GO:0097525)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:1903561 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0015440 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.0 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants