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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for FUBP1

Z-value: 1.30

Motif logo

Transcription factors associated with FUBP1

Gene Symbol	Gene ID	Gene Info
FUBP1 Ensembl NCBI GeneCards UniProt	ENSG00000162613.12	FUBP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
FUBP1	chr1_78416310_78416461	28360	0.127943	-0.73	2.7e-02	Click!
FUBP1	chr1_78439235_78439436	5410	0.170768	-0.57	1.1e-01	Click!
FUBP1	chr1_78440457_78440608	4213	0.181598	-0.48	1.9e-01	Click!
FUBP1	chr1_78416706_78416961	27912	0.128766	-0.46	2.1e-01	Click!
FUBP1	chr1_78436297_78436448	8373	0.159883	-0.43	2.5e-01	Click!

Activity of the FUBP1 motif across conditions

Conditions sorted by the z-value of the FUBP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_98717947_98718887	0.36	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	23225	0.2
chr14_70180420_70180571	0.33	SRSF5	serine/arginine-rich splicing factor 5	13122	0.24
chr3_50410474_50410625	0.31	XXcos-LUCA11.4		5653	0.09
chr16_30066961_30067112	0.31	ALDOA	aldolase A, fructose-bisphosphate	2581	0.11
chr3_107763286_107763437	0.30	CD47	CD47 molecule	13847	0.3
chr2_191513228_191513379	0.29	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)	318	0.91
chr21_46312526_46312824	0.29	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	17870	0.1
chr14_98622440_98622591	0.28	ENSG00000222066	.	175572	0.03
chr12_111178547_111179341	0.28	PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	1700	0.39
chr12_118768131_118768393	0.27	TAOK3	TAO kinase 3	28648	0.21
chr6_103680064_103680234	0.27	ENSG00000202283	.	350861	0.01
chr8_142231323_142231474	0.27	SLC45A4	solute carrier family 45, member 4	7271	0.16
chr19_10731127_10731278	0.27	SLC44A2	solute carrier family 44 (choline transporter), member 2	4732	0.12
chr6_119618545_119618696	0.26	ENSG00000200732	.	29826	0.21
chr1_40512120_40512273	0.26	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	5642	0.2
chr21_16592051_16592291	0.26	NRIP1	nuclear receptor interacting protein 1	154850	0.04
chr8_101227636_101227787	0.26	ENSG00000199667	.	30345	0.14
chrX_48859192_48859344	0.26	GRIPAP1	GRIP1 associated protein 1	593	0.56
chr8_33412460_33412753	0.25	RNF122	ring finger protein 122	12037	0.13
chr16_8818593_8818759	0.25	ABAT	4-aminobutyrate aminotransferase	4100	0.19
chr5_133387222_133387373	0.24	VDAC1	voltage-dependent anion channel 1	46473	0.14
chr15_91859349_91859500	0.24	SV2B	synaptic vesicle glycoprotein 2B	90324	0.09
chr19_16695114_16695265	0.24	MED26	mediator complex subunit 26	3223	0.11
chr10_33798752_33798923	0.24	NRP1	neuropilin 1	173647	0.03
chr17_65420745_65420896	0.24	ENSG00000201547	.	15823	0.13
chrX_128756598_128756859	0.24	APLN	apelin	26014	0.21
chr1_205599149_205600013	0.23	ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)	1509	0.35
chrX_129254186_129254397	0.23	ELF4	E74-like factor 4 (ets domain transcription factor)	9600	0.2
chr8_66588910_66589255	0.23	MTFR1	mitochondrial fission regulator 1	6866	0.22
chr12_93984747_93985062	0.23	SOCS2	suppressor of cytokine signaling 2	16070	0.18
chr6_14123211_14123362	0.23	CD83	CD83 molecule	5414	0.28
chr13_41929051_41929202	0.23	ENSG00000223280	.	331	0.89
chr19_16258305_16258456	0.23	HSH2D	hematopoietic SH2 domain containing	3834	0.15
chr2_174818495_174818646	0.23	SP3	Sp3 transcription factor	10377	0.31
chr5_40685914_40686124	0.23	PTGER4	prostaglandin E receptor 4 (subtype EP4)	6419	0.22
chrX_109275548_109275699	0.23	ENSG00000208013	.	22934	0.19
chr22_38795449_38796163	0.23	CSNK1E	casein kinase 1, epsilon	1279	0.34
chr10_22540840_22540991	0.23	EBLN1	endogenous Bornavirus-like nucleoprotein 1	41965	0.14
chr12_122898532_122898723	0.22	CLIP1	CAP-GLY domain containing linker protein 1	8489	0.22
chr15_46162513_46162674	0.22	SQRDL	sulfide quinone reductase-like (yeast)	187855	0.03
chr1_204553065_204553216	0.22	RP11-430C7.4		19023	0.14
chr3_31975446_31975713	0.22	OSBPL10	oxysterol binding protein-like 10	47213	0.14
chr1_83043773_83044235	0.22	LPHN2	latrophilin 2	598431	0.0
chr20_58562413_58562564	0.22	CDH26	cadherin 26	1673	0.38
chr12_54672984_54673135	0.22	CBX5	chromobox homolog 5	827	0.29
chr3_182534933_182535084	0.21	ATP11B	ATPase, class VI, type 11B	19897	0.21
chr16_78534160_78534433	0.21	RP11-264L1.4		6169	0.28
chr12_24893513_24893767	0.21	ENSG00000240481	.	33918	0.21
chr19_47820020_47820171	0.21	C5AR1	complement component 5a receptor 1	6964	0.14
chr1_100817300_100817579	0.21	CDC14A	cell division cycle 14A	149	0.96
chr15_50346989_50347245	0.21	ATP8B4	ATPase, class I, type 8B, member 4	7533	0.26
chr1_100819282_100819607	0.21	CDC14A	cell division cycle 14A	939	0.57
chr17_79371033_79371247	0.21	RP11-1055B8.6	Uncharacterized protein	1865	0.2
chr5_148927186_148927463	0.21	CSNK1A1	casein kinase 1, alpha 1	2538	0.24
chr2_201980395_201980546	0.21	CFLAR	CASP8 and FADD-like apoptosis regulator	357	0.82
chr9_136933917_136934117	0.21	BRD3	bromodomain containing 3	360	0.86
chr2_161289913_161290064	0.21	RBMS1	RNA binding motif, single stranded interacting protein 1	17299	0.2
chr5_158267521_158267691	0.20	CTD-2363C16.1		142408	0.05
chr2_234474872_234475097	0.20	USP40	ubiquitin specific peptidase 40	396	0.86
chr21_36260768_36260938	0.20	RUNX1	runt-related transcription factor 1	134	0.98
chr12_57077760_57078152	0.20	PTGES3	prostaglandin E synthase 3 (cytosolic)	3990	0.14
chr1_45668899_45669050	0.20	ZSWIM5	zinc finger, SWIM-type containing 5	3254	0.26
chr4_86655280_86655719	0.20	ENSG00000266421	.	11878	0.26
chr21_47887630_47887781	0.20	DIP2A-IT1	DIP2A intronic transcript 1 (non-protein coding)	5321	0.17
chr5_37346370_37346521	0.20	ENSG00000251880	.	19208	0.18
chr20_62543850_62544001	0.20	ENSG00000199805	.	3617	0.09
chr9_123960312_123961002	0.20	RAB14	RAB14, member RAS oncogene family	3490	0.19
chr9_91047692_91047843	0.20	SPIN1	spindlin 1	44421	0.17
chr9_100926805_100927131	0.20	CORO2A	coronin, actin binding protein, 2A	8198	0.21
chr18_76738214_76738365	0.20	SALL3	spalt-like transcription factor 3	1986	0.46
chr3_119806632_119806783	0.20	GSK3B	glycogen synthase kinase 3 beta	5806	0.22
chr3_71751243_71751726	0.20	EIF4E3	eukaryotic translation initiation factor 4E family member 3	23042	0.2
chr15_99398269_99398432	0.20	IGF1R	insulin-like growth factor 1 receptor	35220	0.16
chr5_138638673_138638824	0.20	ENSG00000199545	.	3207	0.14
chr19_37339471_37339622	0.19	ZNF790	zinc finger protein 790	1669	0.24
chr16_12910804_12910955	0.19	CPPED1	calcineurin-like phosphoesterase domain containing 1	13005	0.18
chrX_15448302_15448453	0.19	BMX	BMX non-receptor tyrosine kinase	33992	0.15
chr18_59856200_59856529	0.19	KIAA1468	KIAA1468	1840	0.31
chr2_101946080_101946252	0.19	ENSG00000264857	.	20254	0.16
chr4_48374879_48375030	0.19	SLAIN2	SLAIN motif family, member 2	4964	0.28
chr19_915577_915728	0.19	KISS1R	KISS1 receptor	1635	0.17
chr15_69866363_69866514	0.19	ENSG00000207119	.	115950	0.05
chr12_120884573_120884899	0.19	GATC	glutamyl-tRNA(Gln) amidotransferase, subunit C	356	0.55
chr16_87767946_87768097	0.19	RP11-278A23.2		13291	0.16
chr13_28493501_28493652	0.19	PDX1	pancreatic and duodenal homeobox 1	581	0.66
chr3_47170891_47171128	0.19	SETD2	SET domain containing 2	34057	0.13
chr1_145661139_145661290	0.19	CD160	CD160 molecule	45647	0.09
chr19_19539763_19539914	0.19	GATAD2A	GATA zinc finger domain containing 2A	1502	0.3
chr5_132288576_132288727	0.19	ENSG00000202417	.	7617	0.15
chr4_103741710_103742196	0.19	UBE2D3	ubiquitin-conjugating enzyme E2D 3	4746	0.17
chr14_23386672_23386823	0.19	RBM23	RNA binding motif protein 23	18	0.93
chrX_38661555_38661850	0.18	MID1IP1	MID1 interacting protein 1	995	0.5
chr1_19794748_19794899	0.18	CAPZB	capping protein (actin filament) muscle Z-line, beta	15756	0.16
chr14_69401611_69401762	0.18	ACTN1	actinin, alpha 1	12579	0.23
chr3_186674135_186674286	0.18	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	18535	0.2
chr12_40627003_40627154	0.18	LRRK2	leucine-rich repeat kinase 2	8202	0.24
chr19_1907912_1908063	0.18	ADAT3	adenosine deaminase, tRNA-specific 3	31	0.78
chr13_33199531_33199682	0.18	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	39042	0.19
chr10_115615104_115615263	0.18	NHLRC2	NHL repeat containing 2	763	0.48
chr6_111790354_111790505	0.18	REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	13985	0.19
chr9_139158921_139159104	0.18	QSOX2	quiescin Q6 sulfhydryl oxidase 2	21325	0.15
chr10_12632571_12632722	0.18	ENSG00000263584	.	11894	0.27
chrX_44884110_44884261	0.18	KDM6A	lysine (K)-specific demethylase 6A	34342	0.22
chr16_84413717_84413987	0.18	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	11719	0.19
chrX_119597210_119597803	0.18	LAMP2	lysosomal-associated membrane protein 2	5341	0.25
chr19_50934673_50934858	0.18	MYBPC2	myosin binding protein C, fast type	1395	0.23
chr1_151196545_151196783	0.18	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	10257	0.1
chr2_134935532_134935768	0.18	ENSG00000263813	.	50954	0.14
chr13_48799322_48799473	0.18	ITM2B	integral membrane protein 2B	7897	0.27
chr12_111807867_111808018	0.18	FAM109A	family with sequence similarity 109, member A	1017	0.54
chr2_228362313_228362464	0.18	AGFG1	ArfGAP with FG repeats 1	10600	0.21
chr1_27577181_27577392	0.18	ENSG00000252098	.	4772	0.16
chr3_188390892_188391164	0.18	ENSG00000207651	.	15541	0.22
chr11_1544049_1544200	0.18	MOB2	MOB kinase activator 2	36148	0.1
chr1_171705490_171705830	0.18	VAMP4	vesicle-associated membrane protein 4	5542	0.2
chr3_48477048_48477199	0.18	CCDC51	coiled-coil domain containing 51	2505	0.13
chr7_101708245_101708396	0.18	CTA-357J21.1		32017	0.19
chr5_43019074_43019523	0.18	CTD-2201E18.3		385	0.66
chr13_30158034_30158185	0.18	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	2820	0.39
chr2_182760548_182760802	0.18	SSFA2	sperm specific antigen 2	3752	0.25
chr2_12959099_12960371	0.17	ENSG00000264370	.	82242	0.11
chr3_141045502_141045653	0.17	ZBTB38	zinc finger and BTB domain containing 38	2522	0.33
chr8_121738828_121738979	0.17	RP11-713M15.1		34590	0.2
chr7_157679283_157679434	0.17	RP11-452C13.1		18128	0.22
chr20_34327925_34328154	0.17	RBM39	RNA binding motif protein 39	720	0.55
chr5_55964707_55964858	0.17	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	62723	0.12
chr7_76851520_76851672	0.17	FGL2	fibrinogen-like 2	22453	0.19
chr12_66698497_66698648	0.17	HELB	helicase (DNA) B	2247	0.27
chr14_45627397_45627548	0.17	FANCM	Fanconi anemia, complementation group M	3510	0.21
chr7_129500510_129500817	0.17	ENSG00000207691	.	85809	0.06
chr13_114119819_114119970	0.17	DCUN1D2-AS	DCUN1D2 antisense RNA	3322	0.17
chr22_41683317_41683468	0.17	RANGAP1	Ran GTPase activating protein 1	1137	0.35
chrX_44926778_44926929	0.17	KDM6A	lysine (K)-specific demethylase 6A	7551	0.3
chr17_1082165_1082334	0.17	ABR	active BCR-related	829	0.6
chr1_43411413_43411601	0.17	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	12993	0.18
chr15_67356770_67357118	0.17	SMAD3	SMAD family member 3	843	0.73
chr22_19073574_19073725	0.17	AC004471.9		35393	0.09
chr12_10368361_10368512	0.17	RP11-656E20.5		1076	0.38
chr3_16490080_16490231	0.17	RFTN1	raftlin, lipid raft linker 1	34217	0.19
chr4_15681074_15681472	0.17	FBXL5	F-box and leucine-rich repeat protein 5	1904	0.29
chr7_19155357_19155508	0.17	TWIST1	twist family bHLH transcription factor 1	1863	0.27
chr4_143325972_143326254	0.17	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	26299	0.28
chr19_46066687_46066838	0.17	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)	21315	0.1
chr11_75380064_75380270	0.17	MAP6	microtubule-associated protein 6	2	0.97
chr2_216993992_216994143	0.17	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	19993	0.19
chr15_63802358_63803207	0.17	USP3	ubiquitin specific peptidase 3	4863	0.26
chr12_65091539_65091893	0.17	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	1387	0.36
chr4_110512749_110512900	0.17	CCDC109B	coiled-coil domain containing 109B	30678	0.18
chr22_40584317_40584468	0.17	TNRC6B	trinucleotide repeat containing 6B	10446	0.26
chr12_69727071_69727222	0.17	LYZ	lysozyme	14975	0.17
chr3_45053532_45053683	0.17	CLEC3B	C-type lectin domain family 3, member B	14068	0.15
chrY_7035946_7036097	0.17	PRKY	protein kinase, Y-linked, pseudogene	106315	0.07
chr6_119214221_119214767	0.17	ASF1A	anti-silencing function 1A histone chaperone	890	0.63
chr17_65825111_65825409	0.16	BPTF	bromodomain PHD finger transcription factor	3002	0.23
chr3_9797020_9797171	0.16	OGG1	8-oxoguanine DNA glycosylase	3508	0.13
chr17_54678795_54679086	0.16	NOG	noggin	7880	0.31
chr8_67526501_67526877	0.16	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1	1160	0.46
chrX_131172208_131172403	0.16	MST4	Serine/threonine-protein kinase MST4	14669	0.21
chr4_84035931_84036357	0.16	PLAC8	placenta-specific 8	189	0.96
chr6_137579705_137579856	0.16	IFNGR1	interferon gamma receptor 1	39194	0.19
chr6_156709882_156710033	0.16	ENSG00000212295	.	10073	0.33
chr6_149081739_149081986	0.16	UST	uronyl-2-sulfotransferase	13398	0.3
chr15_86077549_86077700	0.16	AKAP13	A kinase (PRKA) anchor protein 13	9647	0.21
chr15_77702308_77702459	0.16	PEAK1	pseudopodium-enriched atypical kinase 1	10059	0.23
chr20_48321244_48321782	0.16	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	8902	0.19
chr22_42632196_42632347	0.16	TCF20	transcription factor 20 (AR1)	20823	0.18
chr8_42913895_42914749	0.16	FNTA	farnesyltransferase, CAAX box, alpha	227	0.91
chr12_56609980_56610131	0.16	RNF41	ring finger protein 41	5430	0.07
chr9_89562820_89562971	0.16	GAS1	growth arrest-specific 1	791	0.79
chr9_20398844_20399100	0.16	ENSG00000263790	.	12264	0.18
chr11_73468535_73468693	0.16	RAB6A	RAB6A, member RAS oncogene family	2524	0.21
chr6_12608393_12608818	0.16	PHACTR1	phosphatase and actin regulator 1	109288	0.07
chr15_92414828_92415014	0.16	SLCO3A1	solute carrier organic anion transporter family, member 3A1	17570	0.25
chr11_64529641_64529792	0.16	PYGM	phosphorylase, glycogen, muscle	1947	0.21
chr2_101188537_101188688	0.16	PDCL3	phosducin-like 3	3195	0.21
chr20_3996709_3996860	0.16	RNF24	ring finger protein 24	555	0.8
chr2_62702609_62702952	0.16	ENSG00000241625	.	15533	0.23
chr9_135249138_135249289	0.16	SETX	senataxin	18841	0.17
chr12_31470259_31470509	0.16	FAM60A	family with sequence similarity 60, member A	6712	0.16
chr21_43149115_43149266	0.16	AP001615.9		10343	0.18
chr2_68999011_68999272	0.16	ARHGAP25	Rho GTPase activating protein 25	2792	0.33
chr17_49305755_49305970	0.16	MBTD1	mbt domain containing 1	3277	0.21
chr4_169752762_169753076	0.16	PALLD	palladin, cytoskeletal associated protein	237	0.89
chr16_14399831_14399982	0.16	ENSG00000207639	.	2082	0.29
chr7_27190679_27190886	0.16	HOXA-AS3	HOXA cluster antisense RNA 3	1111	0.21
chrX_47929101_47929252	0.16	ZNF630	zinc finger protein 630	1307	0.34
chr19_35758705_35758856	0.16	USF2	upstream transcription factor 2, c-fos interacting	1101	0.29
chr7_99739342_99739544	0.16	LAMTOR4	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	7087	0.06
chr11_95781083_95781234	0.15	MTMR2	myotubularin related protein 2	123699	0.06
chr5_72252681_72252978	0.15	FCHO2	FCH domain only 2	931	0.64
chr10_131129546_131129832	0.15	MGMT	O-6-methylguanine-DNA methyltransferase	135759	0.05
chr15_93062736_93063031	0.15	C15orf32	chromosome 15 open reading frame 32	47732	0.15
chr2_38595705_38595856	0.15	ATL2	atlastin GTPase 2	7586	0.3
chr21_45079176_45079327	0.15	HSF2BP	heat shock transcription factor 2 binding protein	100	0.62
chr17_38684308_38684459	0.15	TNS4	tensin 4	26534	0.13
chr21_16582150_16582301	0.15	NRIP1	nuclear receptor interacting protein 1	144904	0.05
chr12_77165937_77166088	0.15	ZDHHC17	zinc finger, DHHC-type containing 17	7659	0.3
chr11_117199148_117199640	0.15	CEP164	centrosomal protein 164kDa	575	0.46
chr1_53739428_53739681	0.15	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	1781	0.2
chr11_35061219_35061445	0.15	PDHX	pyruvate dehydrogenase complex, component X	62001	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.3	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:2000051	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.2	GO:0043584	nose development(GO:0043584)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0060912	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.0	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.0	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	GO:0043218	compact myelin(GO:0043218)
0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	GO:0042382	paraspeckles(GO:0042382)
0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	GO:0070652	HAUS complex(GO:0070652)
0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	GO:0031527	filopodium membrane(GO:0031527)
0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	GO:0070820	tertiary granule(GO:0070820)
0.1	GO:0044217	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	GO:0001652	granular component(GO:0001652)
0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	GO:0043259	laminin-10 complex(GO:0043259)
0.1	GO:0043209	myelin sheath(GO:0043209)
0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	GO:0030914	STAGA complex(GO:0030914)
0.2	GO:0032039	integrator complex(GO:0032039)
0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	GO:0072487	MSL complex(GO:0072487)
0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	GO:1903561	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	GO:0042788	polysomal ribosome(GO:0042788)
0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	GO:0008180	COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.3	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	PID MYC PATHWAY	C-MYC pathway
0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.5	PID BMP PATHWAY	BMP receptor signaling
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.3	PID IGF1 PATHWAY	IGF1 pathway
0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.5	PID FANCONI PATHWAY	Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants