Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GATA5

Z-value: 5.03

Motif logo

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Transcription factors associated with GATA5

Gene Symbol Gene ID Gene Info
ENSG00000130700.6 GATA5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
GATA5chr20_61070547_61070698195960.147622-0.818.4e-03Click!
GATA5chr20_61062069_61062220111180.163014-0.781.4e-02Click!
GATA5chr20_61090076_61090227391250.104875-0.752.0e-02Click!
GATA5chr20_61087234_61087385362830.111256-0.722.8e-02Click!
GATA5chr20_61060616_6106076796650.165940-0.703.5e-02Click!

Activity of the GATA5 motif across conditions

Conditions sorted by the z-value of the GATA5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_8171333_8171763 1.85 AC006042.6

17893
0.2
chr12_12772724_12773143 1.68 CREBL2
cAMP responsive element binding protein-like 2
8107
0.21
chr14_98168942_98169096 1.58 RP11-204N11.1
Uncharacterized protein
60149
0.16
chr4_109031937_109032201 1.34 LEF1
lymphoid enhancer-binding factor 1
55388
0.13
chr3_46394034_46394455 1.32 CCR2
chemokine (C-C motif) receptor 2
981
0.53
chr1_226881450_226881679 1.29 ITPKB-IT1
ITPKB intronic transcript 1 (non-protein coding)
18796
0.19
chr1_101763741_101764115 1.26 RP4-575N6.5

55214
0.12
chr3_68106398_68106747 1.22 FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
51199
0.19
chr3_46004963_46005114 1.16 FYCO1
FYVE and coiled-coil domain containing 1
4885
0.19
chr12_50138993_50139144 1.12 TMBIM6
transmembrane BAX inhibitor motif containing 6
1868
0.31
chr2_204578772_204578923 1.10 CD28
CD28 molecule
7431
0.25
chr2_197014969_197015443 1.10 RP11-347P5.1

781
0.66
chr15_60856843_60856994 1.10 RORA
RAR-related orphan receptor A
27822
0.16
chr1_100858074_100858225 1.10 ENSG00000216067
.
13818
0.2
chr1_198490250_198490539 1.07 ATP6V1G3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
19410
0.27
chrX_20458891_20459042 1.07 ENSG00000252978
.
11260
0.3
chr17_76015892_76016121 1.06 TNRC6C
trinucleotide repeat containing 6C
11597
0.19
chr5_80052245_80052416 1.05 DHFR
dihydrofolate reductase
101528
0.06
chr3_136639103_136639532 1.03 NCK1
NCK adaptor protein 1
7564
0.2
chr2_143984062_143984213 1.02 RP11-190J23.1

54396
0.16
chr2_207553820_207554094 1.02 ENSG00000207319
.
11952
0.17
chr2_12850330_12850505 1.01 TRIB2
tribbles pseudokinase 2
6598
0.28
chr2_12657678_12657910 1.01 ENSG00000207183
.
106167
0.08
chr12_68597323_68597507 1.00 IL26
interleukin 26
22186
0.2
chr17_73375733_73376161 0.99 RP11-16C1.2

6130
0.1
chr12_72160885_72161036 0.97 RAB21
RAB21, member RAS oncogene family
12306
0.22
chr7_50358519_50358831 0.96 IKZF1
IKAROS family zinc finger 1 (Ikaros)
8570
0.29
chr3_105474089_105474240 0.96 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
53119
0.19
chr13_109061568_109062120 0.93 ENSG00000223177
.
108165
0.07
chr2_42362844_42363203 0.92 EML4
echinoderm microtubule associated protein like 4
33467
0.17
chr5_56499480_56499779 0.92 GPBP1
GC-rich promoter binding protein 1
10319
0.25
chr1_66809133_66809425 0.91 PDE4B
phosphodiesterase 4B, cAMP-specific
10786
0.3
chr14_45131512_45131831 0.91 ENSG00000238501
.
95462
0.08
chr4_153000457_153000739 0.91 ENSG00000253077
.
107833
0.07
chr1_115020478_115020629 0.90 ENSG00000201114
.
12793
0.21
chr4_80918707_80918911 0.90 ANTXR2
anthrax toxin receptor 2
74908
0.12
chr18_60825707_60826108 0.89 RP11-299P2.1

7354
0.25
chr11_62480758_62481047 0.89 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
3585
0.07
chr8_41826408_41826559 0.89 KAT6A
K(lysine) acetyltransferase 6A
10602
0.23
chr14_102297211_102297362 0.88 CTD-2017C7.1

8582
0.16
chr4_109027301_109027793 0.88 LEF1
lymphoid enhancer-binding factor 1
59910
0.12
chr6_24841595_24841746 0.88 ENSG00000263391
.
1377
0.42
chr7_114645798_114646091 0.88 MDFIC
MyoD family inhibitor domain containing
72020
0.13
chr3_45985263_45985436 0.87 CXCR6
chemokine (C-X-C motif) receptor 6
385
0.83
chr13_41176451_41176709 0.87 FOXO1
forkhead box O1
64154
0.11
chr13_100192828_100193120 0.87 ENSG00000212197
.
4324
0.21
chr1_168391686_168391980 0.87 ENSG00000207974
.
47071
0.16
chr14_98642580_98643004 0.86 ENSG00000222066
.
155295
0.04
chr2_106383531_106383975 0.86 NCK2
NCK adaptor protein 2
21565
0.26
chr2_68947558_68947872 0.86 ARHGAP25
Rho GTPase activating protein 25
10081
0.25
chr8_126947838_126948180 0.86 ENSG00000206695
.
34814
0.24
chr15_38844243_38844421 0.86 RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
7951
0.18
chr9_34194975_34195136 0.85 ENSG00000200141
.
150
0.94
chr20_39706690_39706988 0.85 TOP1
topoisomerase (DNA) I
49381
0.12
chrX_40585778_40585929 0.85 MED14-AS1
MED14 antisense RNA 1
8799
0.22
chr10_131905063_131905214 0.85 GLRX3
glutaredoxin 3
29525
0.25
chr3_171047710_171047974 0.84 TNIK
TRAF2 and NCK interacting kinase
104342
0.07
chr13_77594101_77594252 0.84 FBXL3
F-box and leucine-rich repeat protein 3
7109
0.19
chr4_103517654_103517805 0.84 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
18708
0.21
chr4_6701264_6701696 0.84 S100P
S100 calcium binding protein P
6684
0.15
chr18_60958829_60959054 0.84 RP11-28F1.2

22374
0.16
chr6_492948_493099 0.83 RP1-20B11.2

31148
0.23
chr6_143173561_143173779 0.83 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
15486
0.27
chr4_154452350_154452548 0.83 KIAA0922
KIAA0922
24599
0.23
chr7_7286874_7287105 0.83 C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
13038
0.25
chr3_128481294_128481586 0.83 ENSG00000244232
.
22550
0.16
chr8_59928428_59928579 0.82 RP11-328K2.1

23006
0.24
chr5_110569357_110569585 0.82 CAMK4
calcium/calmodulin-dependent protein kinase IV
9687
0.23
chr11_128293469_128293620 0.82 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
81745
0.1
chr2_204569801_204570081 0.82 CD28
CD28 molecule
1257
0.56
chr13_41932919_41933111 0.81 ENSG00000223280
.
4220
0.23
chr9_77771490_77771711 0.81 ENSG00000200041
.
24937
0.18
chr11_102291963_102292114 0.81 TMEM123
transmembrane protein 123
28145
0.14
chr4_78726984_78727206 0.81 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
13122
0.26
chr10_14569816_14570147 0.81 FAM107B
family with sequence similarity 107, member B
4728
0.27
chr11_118638953_118639104 0.81 DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
22560
0.13
chr2_235231760_235231911 0.80 ARL4C
ADP-ribosylation factor-like 4C
173409
0.03
chr13_20212803_20212954 0.80 MPHOSPH8
M-phase phosphoprotein 8
5057
0.23
chr5_66457817_66458109 0.80 MAST4
microtubule associated serine/threonine kinase family member 4
19701
0.24
chr18_33549710_33549967 0.80 C18orf21
chromosome 18 open reading frame 21
2208
0.31
chr1_101577270_101577506 0.79 ENSG00000252765
.
21321
0.18
chr1_78437254_78437415 0.79 FUBP1
far upstream element (FUSE) binding protein 1
7411
0.16
chr1_160420975_160421137 0.79 VANGL2
VANGL planar cell polarity protein 2
50680
0.08
chr2_158270502_158270653 0.79 CYTIP
cytohesin 1 interacting protein
25349
0.19
chr11_82672277_82672428 0.79 PRCP
prolylcarboxypeptidase (angiotensinase C)
9274
0.19
chr2_228363455_228363606 0.79 AGFG1
ArfGAP with FG repeats 1
9458
0.22
chr16_80598344_80598524 0.78 RP11-525K10.3

1402
0.4
chr8_22395773_22395982 0.78 RP11-582J16.4

7041
0.12
chr12_92272115_92272281 0.78 C12orf79
chromosome 12 open reading frame 79
258599
0.02
chr4_111436710_111436861 0.78 RP11-380D23.1

3876
0.28
chr4_36388271_36388560 0.78 RP11-431M7.2

5617
0.32
chr18_23646752_23646903 0.78 SS18
synovial sarcoma translocation, chromosome 18
23233
0.24
chr15_91851085_91851631 0.78 SV2B
synaptic vesicle glycoprotein 2B
82258
0.1
chr6_128255423_128255607 0.78 THEMIS
thymocyte selection associated
15739
0.26
chr5_39180897_39181128 0.78 FYB
FYN binding protein
22117
0.24
chr3_188552513_188552664 0.77 TPRG1
tumor protein p63 regulated 1
112415
0.07
chr6_119116970_119117197 0.77 MCM9
minichromosome maintenance complex component 9
33333
0.2
chr14_98657122_98657458 0.77 ENSG00000222066
.
140797
0.05
chr2_158319985_158320216 0.77 CYTIP
cytohesin 1 interacting protein
19446
0.21
chr13_75897174_75897393 0.77 TBC1D4
TBC1 domain family, member 4
18384
0.24
chr10_22957746_22957955 0.77 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
45187
0.19
chr13_97868033_97868184 0.77 MBNL2
muscleblind-like splicing regulator 2
5580
0.32
chr1_198657070_198657411 0.77 RP11-553K8.5

21050
0.23
chr12_65043306_65043516 0.77 RP11-338E21.3

5388
0.14
chr7_44668438_44669074 0.77 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
4695
0.22
chr18_9181395_9181570 0.77 ANKRD12
ankyrin repeat domain 12
902
0.57
chr18_29609160_29609324 0.77 RNF125
ring finger protein 125, E3 ubiquitin protein ligase
10907
0.15
chr6_34660977_34661157 0.76 ENSG00000238484
.
510
0.67
chr2_162020320_162020598 0.76 TANK
TRAF family member-associated NFKB activator
3222
0.27
chr2_158749980_158750131 0.76 UPP2
uridine phosphorylase 2
16841
0.16
chr7_150175695_150176207 0.76 GIMAP8
GTPase, IMAP family member 8
28233
0.14
chr18_2606333_2606484 0.76 NDC80
NDC80 kinetochore complex component
4372
0.17
chr12_27124096_27124264 0.76 RP11-421F16.3

339
0.84
chr1_198662530_198662806 0.76 RP11-553K8.5

26478
0.22
chr4_110496140_110496528 0.76 CCDC109B
coiled-coil domain containing 109B
14188
0.22
chr17_46503996_46504323 0.76 SKAP1
src kinase associated phosphoprotein 1
3393
0.19
chr6_36499711_36499862 0.75 ENSG00000239964
.
9818
0.14
chr14_75997420_75997632 0.75 BATF
basic leucine zipper transcription factor, ATF-like
8623
0.19
chr13_49017913_49018064 0.75 LPAR6
lysophosphatidic acid receptor 6
852
0.73
chr2_197995272_197995665 0.75 ANKRD44
ankyrin repeat domain 44
8011
0.27
chr12_120450626_120450780 0.75 CCDC64
coiled-coil domain containing 64
23030
0.17
chr10_33375837_33376051 0.75 ENSG00000263576
.
11620
0.23
chr1_111212434_111212585 0.75 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
5146
0.2
chr14_102287538_102287689 0.75 CTD-2017C7.2

10955
0.15
chr17_47736729_47736880 0.74 SPOP
speckle-type POZ protein
12812
0.15
chr2_68606940_68607120 0.74 AC015969.3

14314
0.17
chr3_152023320_152023535 0.74 MBNL1
muscleblind-like splicing regulator 1
5440
0.24
chr2_197053494_197053645 0.74 STK17B
serine/threonine kinase 17b
12342
0.19
chr18_2973993_2974144 0.74 RP11-737O24.1

7052
0.16
chr12_67876278_67876429 0.74 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
165765
0.04
chr2_204799302_204799466 0.74 ICOS
inducible T-cell co-stimulator
2087
0.43
chrX_118782694_118782994 0.74 ENSG00000211578
.
2033
0.29
chr16_84583603_84583764 0.74 TLDC1
TBC/LysM-associated domain containing 1
3956
0.22
chr1_100918680_100918971 0.73 RP5-837M10.4

32728
0.17
chr18_56381121_56381430 0.73 RP11-126O1.4

36429
0.12
chr6_126150884_126151117 0.73 NCOA7-AS1
NCOA7 antisense RNA 1
10996
0.18
chr12_69014637_69014850 0.73 ENSG00000206650
.
6412
0.22
chrX_131120334_131120663 0.73 ENSG00000265686
.
10375
0.22
chr2_86261271_86261552 0.73 POLR1A
polymerase (RNA) I polypeptide A, 194kDa
71867
0.08
chr2_158305057_158305360 0.73 CYTIP
cytohesin 1 interacting protein
4554
0.25
chr7_104679926_104680167 0.73 KMT2E
lysine (K)-specific methyltransferase 2E
25138
0.14
chr15_44834996_44835147 0.73 EIF3J
eukaryotic translation initiation factor 3, subunit J
5690
0.16
chr14_25162667_25162947 0.73 GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
59334
0.11
chr17_1774262_1774541 0.72 RPA1
replication protein A1, 70kDa
7928
0.16
chr3_101739896_101740103 0.72 ENSG00000202177
.
66078
0.12
chr14_98485625_98485776 0.72 C14orf64
chromosome 14 open reading frame 64
41239
0.22
chr3_108556590_108556741 0.72 TRAT1
T cell receptor associated transmembrane adaptor 1
15046
0.25
chr5_53933400_53933551 0.72 SNX18
sorting nexin 18
119882
0.06
chr17_38768487_38768663 0.72 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
19967
0.13
chr14_66394986_66395728 0.72 CTD-2014B16.3
Uncharacterized protein
75884
0.11
chr6_12125817_12125968 0.72 HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
87
0.98
chr2_191384833_191385198 0.72 TMEM194B
transmembrane protein 194B
14068
0.16
chr12_9177186_9177502 0.72 RP11-259O18.4

28182
0.13
chr6_36085891_36086042 0.71 MAPK13
mitogen-activated protein kinase 13
12132
0.17
chr3_186757014_186757165 0.71 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
4442
0.28
chr3_71128590_71128951 0.71 FOXP1
forkhead box P1
13852
0.3
chr14_22982375_22982791 0.71 TRAJ15
T cell receptor alpha joining 15
15997
0.1
chr1_14061469_14061763 0.71 PRDM2
PR domain containing 2, with ZNF domain
14282
0.22
chr8_64111990_64112141 0.71 YTHDF3
YTH domain family, member 3
11977
0.24
chr3_73061784_73062060 0.71 ENSG00000238959
.
15037
0.16
chr3_157827019_157827212 0.71 RSRC1
arginine/serine-rich coiled-coil 1
726
0.71
chr2_99341827_99342042 0.71 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
1225
0.54
chr3_56816249_56816696 0.71 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
6787
0.3
chr11_118207665_118207816 0.70 CD3D
CD3d molecule, delta (CD3-TCR complex)
3912
0.14
chr7_86997924_86998369 0.70 CROT
carnitine O-octanoyltransferase
22495
0.21
chr8_71310723_71310874 0.70 NCOA2
nuclear receptor coactivator 2
4024
0.28
chr18_13466022_13466195 0.70 LDLRAD4
low density lipoprotein receptor class A domain containing 4
1094
0.33
chr14_22998856_22999007 0.70 TRAJ15
T cell receptor alpha joining 15
351
0.79
chr7_127223009_127223160 0.70 GCC1
GRIP and coiled-coil domain containing 1
2577
0.22
chr13_74197481_74197632 0.70 KLF12
Kruppel-like factor 12
371630
0.01
chr14_76005308_76005459 0.70 BATF
basic leucine zipper transcription factor, ATF-like
16480
0.17
chrX_44942775_44943113 0.70 KDM6A
lysine (K)-specific demethylase 6A
7118
0.3
chr4_114821736_114822076 0.70 RP11-26P13.2

42506
0.19
chrX_48585011_48585162 0.69 ENSG00000206723
.
2120
0.19
chr15_60989447_60989624 0.69 RP11-219B17.2

15709
0.21
chr2_149412300_149412614 0.69 EPC2
enhancer of polycomb homolog 2 (Drosophila)
9468
0.3
chr3_114051977_114052128 0.69 ENSG00000207770
.
16636
0.16
chr3_32344523_32344885 0.69 ENSG00000207857
.
43484
0.14
chr12_21766078_21766229 0.69 GYS2
glycogen synthase 2 (liver)
8372
0.2
chr3_112627608_112627759 0.69 CD200R1L
CD200 receptor 1-like
61980
0.09
chr7_135183567_135183787 0.69 CNOT4
CCR4-NOT transcription complex, subunit 4
11147
0.25
chr16_22002852_22003138 0.69 PDZD9
PDZ domain containing 9
9424
0.16
chr16_53492869_53493169 0.68 RBL2
retinoblastoma-like 2 (p130)
9031
0.16
chr20_46139801_46139952 0.68 NCOA3
nuclear receptor coactivator 3
9191
0.17
chr3_43362518_43362690 0.68 ENSG00000241939
.
6161
0.19
chr17_63022313_63022486 0.68 RP11-583F2.5

25628
0.14
chr4_143267653_143267804 0.68 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
40631
0.23
chr11_128195267_128195435 0.68 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
179938
0.03
chr15_22548341_22548683 0.68 ENSG00000221641
.
35232
0.13
chr2_99279276_99279650 0.68 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
473
0.84
chr12_82749470_82749662 0.68 CCDC59
coiled-coil domain containing 59
2609
0.25
chr17_11959158_11959309 0.68 ENSG00000252707
.
19279
0.17
chr20_8132706_8132867 0.68 PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
19484
0.25
chr8_82087006_82087305 0.67 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
62852
0.13
chr18_2964998_2965212 0.67 RP11-737O24.1

1911
0.28
chr4_123039590_123039741 0.67 ENSG00000241037
.
30699
0.19
chr2_191929101_191929252 0.67 ENSG00000231858
.
42924
0.12
chr9_80727787_80728307 0.67 ENSG00000222452
.
52334
0.16
chr12_40023474_40023652 0.67 C12orf40
chromosome 12 open reading frame 40
3578
0.29
chr4_110571544_110571753 0.67 AC004067.5

41512
0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of GATA5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.9 0.9 GO:0002326 B cell lineage commitment(GO:0002326)
0.8 2.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.8 2.3 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.8 5.3 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.7 0.7 GO:0002664 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.6 1.9 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.6 1.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.5 1.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.5 1.9 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 3.2 GO:0007172 signal complex assembly(GO:0007172)
0.4 1.7 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.4 1.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.4 2.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.4 1.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 1.9 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.4 1.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.4 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.4 1.1 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.4 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 1.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.3 0.7 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.3 0.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.3 1.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 1.3 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 1.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 1.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.3 1.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 2.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 3.3 GO:0043368 positive T cell selection(GO:0043368)
0.3 2.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 0.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 2.0 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.3 0.8 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.3 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 1.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 0.8 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.3 0.8 GO:0072033 renal vesicle formation(GO:0072033)
0.2 0.7 GO:0042511 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510) positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.2 1.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.7 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.2 0.7 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.2 0.7 GO:0002507 tolerance induction(GO:0002507)
0.2 1.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.2 15.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.2 1.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.7 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.2 0.7 GO:0006772 thiamine metabolic process(GO:0006772)
0.2 0.4 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.2 1.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 0.2 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 0.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 2.1 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.2 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.2 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.2 GO:0033622 integrin activation(GO:0033622)
0.2 0.6 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 0.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 1.0 GO:0007097 nuclear migration(GO:0007097)
0.2 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.8 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.6 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.2 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.9 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.2 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 0.4 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.2 0.7 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.2 1.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 0.4 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.2 1.2 GO:0060037 pharyngeal system development(GO:0060037)
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 0.5 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.2 0.5 GO:0045056 transcytosis(GO:0045056)
0.2 0.3 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.2 0.2 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2 2.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 1.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.6 GO:0070670 response to interleukin-4(GO:0070670)
0.2 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.2 0.5 GO:0001821 histamine secretion(GO:0001821)
0.2 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.2 0.5 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.2 0.6 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.4 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.3 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.3 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 1.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.5 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.4 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.5 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0072111 cell proliferation involved in kidney development(GO:0072111)
0.1 0.7 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.4 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 0.2 GO:0048548 regulation of pinocytosis(GO:0048548)
0.1 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.2 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.1 0.3 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.9 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.4 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.7 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.6 GO:0070265 necrotic cell death(GO:0070265)
0.1 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.1 0.2 GO:0046877 regulation of saliva secretion(GO:0046877)
0.1 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.1 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 0.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.2 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.1 1.1 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.3 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.2 GO:0032106 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.1 1.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.1 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1 0.1 GO:0061054 dermatome development(GO:0061054)
0.1 0.2 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1 0.3 GO:0051642 centrosome localization(GO:0051642)
0.1 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.5 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.1 1.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 1.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.5 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.4 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.2 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1 2.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.4 GO:0016236 macroautophagy(GO:0016236)
0.1 0.3 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1 0.7 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1 0.2 GO:0046958 nonassociative learning(GO:0046958)
0.1 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0021610 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.1 0.2 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.4 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.1 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.1 GO:0048539 bone marrow development(GO:0048539)
0.1 2.3 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1 0.2 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.1 0.3 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 1.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.1 1.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.0 GO:1900181 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.1 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.3 GO:0022011 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.9 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.1 GO:0021561 facial nerve development(GO:0021561)
0.1 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.4 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.1 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 0.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.7 GO:0031648 protein destabilization(GO:0031648)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1 0.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.7 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.2 GO:0051775 response to redox state(GO:0051775)
0.1 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.1 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.4 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.1 0.3 GO:0034243 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 0.1 GO:0031223 auditory behavior(GO:0031223)
0.1 0.6 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.1 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.3 GO:0042098 T cell proliferation(GO:0042098)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.3 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.1 GO:0072224 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.1 0.1 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.4 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.1 GO:0001832 blastocyst growth(GO:0001832)
0.1 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.4 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.1 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.2 GO:0046033 AMP metabolic process(GO:0046033)
0.1 0.1 GO:0016556 mRNA modification(GO:0016556)
0.1 0.2 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.2 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.1 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.2 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.4 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.0 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.1 0.7 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.2 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.1 0.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.1 1.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 4.5 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.1 0.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 0.2 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.1 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.3 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.1 0.1 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.1 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.1 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.2 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:0033483 gas homeostasis(GO:0033483)
0.1 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.4 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.3 GO:0010288 response to lead ion(GO:0010288)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0006390 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.2 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 2.3 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.7 GO:0019226 transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0072234 metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 1.0 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.3 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 1.1 GO:0021549 cerebellum development(GO:0021549)
0.0 0.1 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0045136 development of secondary sexual characteristics(GO:0045136)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.2 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0051224 negative regulation of protein transport(GO:0051224)
0.0 0.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.2 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.9 GO:0042384 cilium assembly(GO:0042384)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0042345 regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.0 0.1 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0032094 response to food(GO:0032094)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0060177 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991) regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 1.5 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.3 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.1 GO:1901998 antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0015872 dopamine transport(GO:0015872)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0042754 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.0 GO:0003157 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.0 GO:0035089 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.0 GO:0032645 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645) granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.3 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0006273 lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0008595 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.3 GO:1903039 positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0048880 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.0 GO:0070664 negative regulation of leukocyte proliferation(GO:0070664)
0.0 2.7 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.3 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.0 GO:1902750 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) mitotic G2/M transition checkpoint(GO:0044818) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 2.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.3 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 2.5 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.0 GO:0032202 telomere assembly(GO:0032202)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.9 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0 0.1 GO:0002209 behavioral defense response(GO:0002209)
0.0 0.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233) negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.0 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0097028 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.1 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0072655 establishment of protein localization to mitochondrion(GO:0072655)
0.0 0.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.4 4.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 1.1 GO:0072487 MSL complex(GO:0072487)
0.3 2.6 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.0 GO:0005827 polar microtubule(GO:0005827)
0.2 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.5 GO:0032449 CBM complex(GO:0032449)
0.2 1.0 GO:0005667 transcription factor complex(GO:0005667)
0.2 0.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.2 1.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 0.4 GO:0030880 RNA polymerase complex(GO:0030880)
0.2 2.1 GO:0001772 immunological synapse(GO:0001772)
0.2 1.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.2 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.2 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 0.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.2 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 4.9 GO:0030175 filopodium(GO:0030175)
0.1 0.1 GO:0071547 piP-body(GO:0071547)
0.1 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 0.1 GO:0045298 tubulin complex(GO:0045298)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.4 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.4 GO:0000800 lateral element(GO:0000800)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 1.0 GO:0045120 pronucleus(GO:0045120)
0.1 0.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.4 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.1 1.2 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.1 6.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.3 GO:0030904 retromer complex(GO:0030904)
0.1 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0042627 chylomicron(GO:0042627)
0.1 0.5 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.5 GO:0034464 BBSome(GO:0034464)
0.1 0.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0071203 WASH complex(GO:0071203)
0.1 0.1 GO:0071817 MMXD complex(GO:0071817)
0.1 0.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.6 GO:0043209 myelin sheath(GO:0043209)
0.1 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.9 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1 0.4 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.5 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 5.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.8 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 2.3 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.0 GO:0009295 nucleoid(GO:0009295)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0000228 nuclear chromosome(GO:0000228)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0000803 sex chromosome(GO:0000803)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 6.8 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.7 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0038201 TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.4 GO:0099568 cytoplasmic region(GO:0099568)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0016460 myosin II complex(GO:0016460)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 1.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 9.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.6 GO:0044391 ribosomal subunit(GO:0044391)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 4.4 GO:0005768 endosome(GO:0005768)
0.0 52.6 GO:0005634 nucleus(GO:0005634)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.2 GO:0005874 microtubule(GO:0005874)
0.0 0.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 2.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0031672 A band(GO:0031672)
0.0 0.0 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 2.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 5.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 1.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4 3.4 GO:0030332 cyclin binding(GO:0030332)
0.4 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 1.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.4 2.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4 2.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 2.8 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.3 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 0.9 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.3 0.9 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.3 4.3 GO:0004697 protein kinase C activity(GO:0004697)
0.3 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.3 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.4 GO:0031013 troponin I binding(GO:0031013)
0.3 2.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 1.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 3.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 5.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.0 GO:0015925 galactosidase activity(GO:0015925)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.7 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 0.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 0.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.2 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.4 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.2 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 1.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 2.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 2.7 GO:0015026 coreceptor activity(GO:0015026)
0.2 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 0.6 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.2 0.9 GO:0051400 BH domain binding(GO:0051400)
0.2 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 1.0 GO:0004568 chitinase activity(GO:0004568)
0.1 1.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.9 GO:0050733 RS domain binding(GO:0050733)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 3.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 2.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.1 0.5 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.9 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 1.0 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.6 GO:0004904 interferon receptor activity(GO:0004904)
0.1 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 3.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 5.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 2.0 GO:0043621 protein self-association(GO:0043621)
0.1 0.6 GO:0060229 lipase activator activity(GO:0060229)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.6 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.1 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.3 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.1 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.6 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.5 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1 0.3 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 0.1 GO:0035197 siRNA binding(GO:0035197)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0045502 dynein binding(GO:0045502)
0.1 0.4 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.1 0.1 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 2.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.2 GO:0048156 tau protein binding(GO:0048156)
0.1 0.6 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.4 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.5 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.2 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.7 GO:0003823 antigen binding(GO:0003823)
0.1 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.3 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.2 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.1 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.2 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 2.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.3 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0033558 protein deacetylase activity(GO:0033558)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 1.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.1 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 3.5 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 3.0 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0004527 exonuclease activity(GO:0004527)
0.0 1.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 9.2 GO:0003723 RNA binding(GO:0003723)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.0 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.6 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 4.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.7 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 0.0 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.0 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.0 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 3.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0005416 cation:amino acid symporter activity(GO:0005416) L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 17.7 GO:0003676 nucleic acid binding(GO:0003676)
0.0 0.1 GO:0032934 sterol binding(GO:0032934)
0.0 0.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 21.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 2.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 3.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 4.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 6.1 PID CD40 PATHWAY CD40/CD40L signaling
0.2 4.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 1.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 7.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 2.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 3.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 4.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.0 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.4 PID MYC PATHWAY C-MYC pathway
0.1 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 5.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.5 7.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 1.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 3.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 4.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 5.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 1.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 4.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 3.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 3.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 3.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 1.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.9 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 5.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 5.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.9 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 0.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.2 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.2 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.1 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.1 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 5.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.0 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.0 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 2.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen