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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GATA6

Z-value: 0.21

Motif logo

Transcription factors associated with GATA6

Gene Symbol	Gene ID	Gene Info
GATA6 Ensembl NCBI GeneCards UniProt	ENSG00000141448.4	GATA6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GATA6	chr18_19749352_19749503	23	0.968795	0.85	3.6e-03	Click!
GATA6	chr18_19750426_19750714	324	0.850451	0.76	1.7e-02	Click!
GATA6	chr18_19749074_19749225	255	0.892483	0.72	2.8e-02	Click!
GATA6	chr18_19745398_19745549	3931	0.172004	0.69	3.8e-02	Click!
GATA6	chr18_19749689_19749991	436	0.777502	0.67	4.9e-02	Click!

Activity of the GATA6 motif across conditions

Conditions sorted by the z-value of the GATA6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_130628032_130628183	0.04	ENSG00000263979	.	3667	0.1
chr1_63260192_63260486	0.03	ATG4C	autophagy related 4C, cysteine peptidase	9435	0.28
chr1_117528994_117529403	0.02	CD101	CD101 molecule	15184	0.16
chr9_100695698_100695849	0.02	C9orf156	chromosome 9 open reading frame 156	10921	0.14
chr14_61870595_61870929	0.02	PRKCH	protein kinase C, eta	13350	0.24
chr10_95171957_95172108	0.02	MYOF	myoferlin	69919	0.1
chr7_50250289_50250673	0.02	AC020743.2		68062	0.11
chr17_78676894_78677122	0.02	RP11-28G8.1		102424	0.06
chr7_50353056_50353247	0.02	IKZF1	IKAROS family zinc finger 1 (Ikaros)	4833	0.32
chr11_121460600_121460753	0.02	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	452	0.9
chr1_230331179_230331330	0.02	RP5-956O18.2		72975	0.1
chr6_159439729_159439953	0.02	RP1-111C20.4		7137	0.19
chr1_239883809_239884265	0.02	CHRM3	cholinergic receptor, muscarinic 3	1194	0.46
chr15_52524118_52524315	0.02	GNB5	guanine nucleotide binding protein (G protein), beta 5	40650	0.12
chr9_5842844_5842995	0.02	ERMP1	endoplasmic reticulum metallopeptidase 1	9802	0.2
chr6_164386761_164386912	0.02	ENSG00000266128	.	125243	0.06
chr17_74812829_74813105	0.02	MFSD11	major facilitator superfamily domain containing 11	49444	0.08
chr17_29638570_29638721	0.02	EVI2B	ecotropic viral integration site 2B	2457	0.2
chr1_160537117_160537336	0.02	CD84	CD84 molecule	12037	0.14
chr12_70321695_70321901	0.02	MYRFL	myelin regulatory factor-like	1361	0.5
chr8_97290954_97291105	0.02	PTDSS1	phosphatidylserine synthase 1	16391	0.15
chr16_27244085_27244503	0.02	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	105	0.96
chr19_16373633_16373875	0.02	CTD-2562J15.6		30632	0.12
chr13_50552535_50552686	0.02	TRIM13	tripartite motif containing 13	17414	0.12
chr1_26298239_26298465	0.02	ENSG00000207237	.	7664	0.11
chr20_57844647_57845067	0.02	EDN3	endothelin 3	30625	0.2
chr8_97293950_97294101	0.02	PTDSS1	phosphatidylserine synthase 1	13395	0.16
chr11_63648819_63649100	0.02	ENSG00000202089	.	1198	0.38
chr1_160605831_160606299	0.02	SLAMF1	signaling lymphocytic activation molecule family member 1	10746	0.16
chr21_38597297_38597914	0.02	ENSG00000263969	.	9699	0.16
chr11_67178315_67178466	0.02	CARNS1	carnosine synthase 1	4759	0.07
chr2_158767858_158768009	0.02	ENSG00000251980	.	1351	0.44
chr19_54898963_54899137	0.02	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	16885	0.09
chr6_135509935_135510087	0.02	MYB	v-myb avian myeloblastosis viral oncogene homolog	2855	0.25
chr12_9177186_9177502	0.02	RP11-259O18.4		28182	0.13
chr3_178983634_178983916	0.02	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3	984	0.55
chrX_70325744_70326037	0.02	CXorf65	chromosome X open reading frame 65	565	0.6
chr7_38231978_38232129	0.02	STARD3NL	STARD3 N-terminal like	14056	0.3
chr9_42926874_42927025	0.02	AC129778.2		67864	0.12
chr2_198144726_198144925	0.02	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	22418	0.16
chr17_32688274_32688552	0.02	CCL1	chemokine (C-C motif) ligand 1	1837	0.3
chr21_47972699_47973025	0.02	ENSG00000272283	.	17153	0.17
chr6_159529160_159529540	0.02	RP11-13P5.2		59035	0.1
chr11_114086673_114087539	0.02	NNMT	nicotinamide N-methyltransferase	41447	0.17
chr9_5843022_5843173	0.02	ERMP1	endoplasmic reticulum metallopeptidase 1	9980	0.2
chr2_112391271_112391480	0.02	ENSG00000266063	.	137336	0.05
chr2_98525890_98526041	0.02	TMEM131	transmembrane protein 131	2256	0.33
chr3_32179771_32179931	0.02	GPD1L	glycerol-3-phosphate dehydrogenase 1-like	31660	0.15
chr1_226921058_226921209	0.02	ITPKB	inositol-trisphosphate 3-kinase B	4026	0.28
chr2_217630360_217630511	0.02	ENSG00000222832	.	27888	0.15
chr5_176356741_176356900	0.02	HK3	hexokinase 3 (white cell)	30487	0.16
chr1_66773813_66773964	0.02	PDE4B	phosphodiesterase 4B, cAMP-specific	22523	0.27
chr1_206260544_206260695	0.02	ENSG00000252692	.	474	0.79
chr18_5293322_5293593	0.02	ZBTB14	zinc finger and BTB domain containing 14	1366	0.56
chr9_82482306_82482544	0.02	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	160744	0.04
chr22_40513481_40513654	0.02	TNRC6B	trinucleotide repeat containing 6B	60362	0.12
chr6_137546259_137546508	0.02	IFNGR1	interferon gamma receptor 1	5797	0.28
chr13_91796537_91796800	0.02	ENSG00000215417	.	206191	0.03
chr20_62739069_62739264	0.02	NPBWR2	neuropeptides B/W receptor 2	642	0.57
chr3_10188290_10188441	0.02	VHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	4893	0.12
chr2_169457921_169458072	0.02	ENSG00000199348	.	5010	0.25
chr9_67099892_67100043	0.02	ENSG00000265285	.	5034	0.33
chr7_77383911_77384062	0.02	RSBN1L	round spermatid basic protein 1-like	4926	0.25
chr14_38677217_38677368	0.02	SSTR1	somatostatin receptor 1	88	0.97
chr2_113428621_113428827	0.02	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	23445	0.17
chr16_25104462_25104914	0.01	LCMT1	leucine carboxyl methyltransferase 1	18362	0.2
chr21_36315540_36315813	0.01	RUNX1	runt-related transcription factor 1	53589	0.17
chr9_95728001_95728291	0.01	FGD3	FYVE, RhoGEF and PH domain containing 3	1903	0.38
chr11_112070521_112070755	0.01	BCO2	beta-carotene oxygenase 2	6441	0.11
chr1_208056573_208056724	0.01	CD34	CD34 molecule	7189	0.29
chr2_98290201_98290458	0.01	LINC01125	long intergenic non-protein coding RNA 1125	462	0.76
chrX_77038763_77038914	0.01	ATRX	alpha thalassemia/mental retardation syndrome X-linked	2864	0.32
chr5_61636869_61637070	0.01	KIF2A	kinesin heavy chain member 2A	20164	0.22
chr9_101878868_101879163	0.01	TGFBR1	transforming growth factor, beta receptor 1	11042	0.2
chr2_227702506_227702657	0.01	RHBDD1	rhomboid domain containing 1	317	0.91
chr20_17491486_17491637	0.01	BFSP1	beaded filament structural protein 1, filensin	20453	0.21
chr10_2951549_2951726	0.01	PFKP	phosphofructokinase, platelet	156888	0.04
chr3_160087726_160088066	0.01	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)	13548	0.15
chr7_101497725_101497887	0.01	CTA-339C12.1		29797	0.18
chr19_31841902_31842053	0.01	TSHZ3	teashirt zinc finger homeobox 3	1524	0.42
chr2_231417375_231417526	0.01	AC010149.4		27198	0.15
chr17_63169666_63169909	0.01	RGS9	regulator of G-protein signaling 9	36195	0.19
chr9_93277885_93278036	0.01	DIRAS2	DIRAS family, GTP-binding RAS-like 2	127426	0.06
chr8_128972530_128972700	0.01	ENSG00000221771	.	264	0.92
chr11_78165185_78165336	0.01	NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	10455	0.2
chr14_70653199_70653350	0.01	RP11-486O13.2		566	0.77
chr9_42574831_42574982	0.01	ENSG00000266353	.	5067	0.31
chr17_17048602_17048898	0.01	MPRIP	myosin phosphatase Rho interacting protein	8916	0.14
chr11_114086418_114086569	0.01	NNMT	nicotinamide N-methyltransferase	42060	0.17
chr2_217281812_217281963	0.01	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	1219	0.41
chr19_16474453_16474697	0.01	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	1811	0.29
chr8_81961331_81961482	0.01	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	62897	0.14
chr12_2901464_2901615	0.01	FKBP4	FK506 binding protein 4, 59kDa	2580	0.18
chr1_204329588_204329739	0.01	PLEKHA6	pleckstrin homology domain containing, family A member 6	619	0.72
chr7_32925349_32925561	0.01	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	5310	0.24
chr5_75810115_75810311	0.01	IQGAP2	IQ motif containing GTPase activating protein 2	33021	0.2
chr4_89526943_89527316	0.01	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	184	0.95
chr6_26478781_26479098	0.01	BTN2A1	butyrophilin, subfamily 2, member A1	13484	0.12
chr17_74117170_74117335	0.01	EXOC7	exocyst complex component 7	405	0.75
chr12_125094240_125094476	0.01	NCOR2	nuclear receptor corepressor 2	42348	0.2
chr1_40628068_40628453	0.01	RLF	rearranged L-myc fusion	1215	0.44
chr7_50254432_50254583	0.01	AC020743.2		72088	0.11
chr5_109192389_109192540	0.01	AC011366.3	Uncharacterized protein	26419	0.26
chr3_127202736_127202887	0.01	TPRA1	transmembrane protein, adipocyte asscociated 1	96469	0.07
chr10_116365078_116365229	0.01	ENSG00000238577	.	51116	0.15
chr3_71754731_71754939	0.01	EIF4E3	eukaryotic translation initiation factor 4E family member 3	19691	0.21
chr2_30482414_30482565	0.01	LBH	limb bud and heart development	27443	0.21
chr8_126275118_126275439	0.01	ENSG00000242170	.	7568	0.27
chr11_6691639_6691994	0.01	MRPL17	mitochondrial ribosomal protein L17	12731	0.1
chr12_58137526_58137677	0.01	TSPAN31	tetraspanin 31	1063	0.22
chr1_113524173_113524422	0.01	SLC16A1	solute carrier family 16 (monocarboxylate transporter), member 1	24662	0.19
chr10_4086226_4086442	0.01	KLF6	Kruppel-like factor 6	258861	0.02
chr7_150179115_150179665	0.01	GIMAP8	GTPase, IMAP family member 8	31672	0.13
chr10_31379930_31380081	0.01	ENSG00000263578	.	25029	0.23
chr13_100028628_100029061	0.01	ENSG00000207719	.	20459	0.19
chr15_66946404_66946592	0.01	SMAD6	SMAD family member 6	48068	0.12
chr7_56019828_56020016	0.01	MRPS17	mitochondrial ribosomal protein S17	266	0.64
chr13_28527067_28527218	0.01	ATP5EP2	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2	7799	0.14
chr7_36241182_36241445	0.01	AC007327.5		29403	0.18
chr12_117488779_117488930	0.01	TESC	tescalcin	4218	0.3
chr11_33925535_33925792	0.01	LMO2	LIM domain only 2 (rhombotin-like 1)	11827	0.21
chr19_51629587_51629738	0.01	SIGLEC9	sialic acid binding Ig-like lectin 9	625	0.53
chr16_75036571_75036722	0.01	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	451	0.84
chr18_77190146_77190297	0.01	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	29829	0.2
chr5_156297018_156297169	0.01	ENSG00000199468	.	55952	0.13
chr1_159055054_159055205	0.01	AIM2	absent in melanoma 2	8438	0.19
chr14_50558921_50559072	0.01	C14orf183	chromosome 14 open reading frame 183	365	0.83
chr9_21047360_21047561	0.01	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	15825	0.18
chr9_126136303_126136518	0.01	CRB2	crumbs homolog 2 (Drosophila)	5242	0.25
chr8_99953508_99953739	0.01	STK3	serine/threonine kinase 3	1176	0.44
chr6_135494903_135495054	0.01	MYB	v-myb avian myeloblastosis viral oncogene homolog	7475	0.2
chr22_38027238_38027450	0.01	SH3BP1	SH3-domain binding protein 1	8138	0.1
chr1_114456887_114457038	0.01	AP4B1	adaptor-related protein complex 4, beta 1 subunit	9139	0.12
chr5_17218896_17219047	0.01	BASP1	brain abundant, membrane attached signal protein 1	1302	0.37
chr2_75043564_75043871	0.01	HK2	hexokinase 2	17391	0.23
chr16_76690596_76690747	0.01	RP11-58C22.1	Uncharacterized protein	103357	0.08
chr19_54858812_54858963	0.01	LILRA4	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4	8466	0.1
chr10_97072027_97072178	0.01	PDLIM1	PDZ and LIM domain 1	21321	0.21
chr6_35275141_35275407	0.01	DEF6	differentially expressed in FDCP 6 homolog (mouse)	2241	0.29
chr12_104953946_104954167	0.01	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	28570	0.2
chr19_48346448_48346599	0.01	TPRX2P	tetra-peptide repeat homeobox 2 pseudogene	8822	0.13
chr2_99348262_99348529	0.01	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	806	0.7
chr8_96224676_96225073	0.01	C8orf37	chromosome 8 open reading frame 37	56555	0.13
chr3_16984516_16984667	0.01	ENSG00000264818	.	9903	0.23
chr17_58459442_58459593	0.01	USP32	ubiquitin specific peptidase 32	9819	0.21
chr2_7061705_7061856	0.01	ENSG00000228203	.	2940	0.24
chr12_92798799_92799064	0.01	RP11-693J15.4		16376	0.18
chr13_32562254_32562405	0.01	EEF1DP3	eukaryotic translation elongation factor 1 delta pseudogene 3	35612	0.17
chr6_27599270_27599557	0.01	ENSG00000238648	.	225	0.94
chr8_8195680_8195853	0.01	SGK223	Tyrosine-protein kinase SgK223	43491	0.16
chr20_42847628_42847998	0.01	OSER1	oxidative stress responsive serine-rich 1	8382	0.17
chr20_37462715_37462866	0.01	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	28423	0.15
chr6_137211346_137211580	0.01	SLC35D3	solute carrier family 35, member D3	31939	0.14
chr10_95325510_95325661	0.01	FFAR4	free fatty acid receptor 4	837	0.58
chr4_185285797_185285948	0.01	IRF2	interferon regulatory factor 2	53872	0.12
chr14_22320921_22321072	0.01	ENSG00000222776	.	72211	0.11
chr1_42610621_42610772	0.01	GUCA2B	guanylate cyclase activator 2B (uroguanylin)	8396	0.21
chr9_96362591_96362784	0.01	PHF2	PHD finger protein 2	23778	0.18
chr5_77790229_77790380	0.01	LHFPL2	lipoma HMGIC fusion partner-like 2	54670	0.16
chr5_156543326_156543684	0.01	HAVCR2	hepatitis A virus cellular receptor 2	6780	0.14
chr3_27399507_27399712	0.01	ENSG00000221573	.	4540	0.22
chr11_128550867_128551052	0.01	RP11-744N12.3		5364	0.2
chr9_117692590_117692826	0.01	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	11	0.99
chr4_99529596_99529747	0.01	TSPAN5	tetraspanin 5	49115	0.15
chr10_70832788_70833015	0.01	SRGN	serglycin	14973	0.18
chr18_56390436_56390587	0.01	RP11-126O1.4		29451	0.14
chr11_121325824_121326252	0.01	RP11-730K11.1		2316	0.33
chr18_43808800_43809044	0.01	C18orf25	chromosome 18 open reading frame 25	54922	0.13
chr4_76944504_76944655	0.01	CXCL10	chemokine (C-X-C motif) ligand 10	71	0.95
chr16_12661045_12661196	0.01	CTD-3037G24.4		9569	0.2
chr9_124412947_124413098	0.01	DAB2IP	DAB2 interacting protein	851	0.7
chr15_75447692_75447843	0.01	ENSG00000252722	.	33760	0.11
chr2_196378029_196378180	0.01	ENSG00000202206	.	656	0.81
chr2_138679588_138679739	0.01	HNMT	histamine N-methyltransferase	41927	0.22
chr9_37301207_37301358	0.01	ENSG00000216070	.	5181	0.23
chr1_206292279_206292571	0.01	C1orf186	chromosome 1 open reading frame 186	3778	0.21
chr5_58879154_58879305	0.01	PDE4D	phosphodiesterase 4D, cAMP-specific	2990	0.41
chr16_67196662_67196813	0.01	HSF4	heat shock transcription factor 4	551	0.45
chr7_93575157_93575308	0.01	AC006378.2		23522	0.14
chr7_129545877_129546028	0.01	UBE2H	ubiquitin-conjugating enzyme E2H	45215	0.1
chr13_28002327_28002478	0.01	GTF3A	general transcription factor IIIA	1693	0.33
chr5_135469095_135469294	0.01	SMAD5	SMAD family member 5	152	0.94
chr5_173392661_173392812	0.01	C5orf47	chromosome 5 open reading frame 47	23426	0.21
chr20_50087701_50087852	0.01	ENSG00000266761	.	18262	0.24
chr1_10474301_10474452	0.01	PGD	phosphogluconate dehydrogenase	14687	0.1
chr1_39718531_39718682	0.01	RP11-420K8.1		4715	0.21
chr8_27276778_27276929	0.01	PTK2B	protein tyrosine kinase 2 beta	11551	0.22
chr1_25916924_25917087	0.01	MAN1C1	mannosidase, alpha, class 1C, member 1	26954	0.16
chr15_78496258_78496409	0.01	ACSBG1	acyl-CoA synthetase bubblegum family member 1	3794	0.18
chr4_90820392_90820543	0.01	MMRN1	multimerin 1	2667	0.36
chr9_135936902_135937053	0.01	CEL	carboxyl ester lipase	388	0.79
chr6_134953808_134954009	0.01	ALDH8A1	aldehyde dehydrogenase 8 family, member A1	296391	0.01
chr5_154191716_154191876	0.01	LARP1	La ribonucleoprotein domain family, member 1	8015	0.17
chr2_58957929_58958080	0.01	FANCL	Fanconi anemia, complementation group L	489497	0.01
chr6_159480470_159480786	0.01	TAGAP	T-cell activation RhoGTPase activating protein	14444	0.19
chr19_57171861_57172196	0.01	ZNF835	zinc finger protein 835	11100	0.14
chr9_108462759_108462910	0.01	TMEM38B	transmembrane protein 38B	431	0.88
chr6_136889409_136889560	0.01	MAP7	microtubule-associated protein 7	17527	0.15
chr4_185744633_185744784	0.01	ACSL1	acyl-CoA synthetase long-chain family member 1	2480	0.27
chr17_19141339_19141495	0.01	EPN2	epsin 2	685	0.56