Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for GRHL1

Z-value: 2.41

Motif logo

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Transcription factors associated with GRHL1

Gene Symbol Gene ID Gene Info
ENSG00000134317.13 grainyhead like transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_10120083_10120407GRHL1151890.161474-0.722.8e-02Click!
chr2_10106881_10107032GRHL1151290.174178-0.684.5e-02Click!
chr2_10122799_10122950GRHL1125600.163663-0.637.0e-02Click!
chr2_10109337_10109488GRHL1175850.167183-0.561.2e-01Click!
chr2_10081034_10081185GRHL142320.2392200.551.2e-01Click!

Activity of the GRHL1 motif across conditions

Conditions sorted by the z-value of the GRHL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_101882560_101882711 2.01 ZPLD1
zona pellucida-like domain containing 1
64547
0.14
chr9_78830303_78830575 1.31 PCSK5
proprotein convertase subtilisin/kexin type 5
26884
0.26
chrX_2815646_2815988 1.25 ARSD-AS1
ARSD antisense RNA 1
7128
0.17
chr2_150023630_150023914 1.19 LYPD6B
LY6/PLAUR domain containing 6B
6782
0.33
chr10_11629983_11630134 1.15 USP6NL
USP6 N-terminal like
14218
0.23
chr8_28558220_28558688 1.15 EXTL3-AS1
EXTL3 antisense RNA 1
316
0.56
chr3_128444618_128444816 1.14 RAB7A
RAB7A, member RAS oncogene family
248
0.92
chr11_8742901_8743052 1.13 ST5
suppression of tumorigenicity 5
2286
0.2
chr10_31321539_31321725 1.11 ZNF438
zinc finger protein 438
766
0.74
chr1_209492900_209493051 1.08 ENSG00000230937
.
112503
0.07
chr12_48148703_48148929 1.06 SLC48A1
solute carrier family 48 (heme transporter), member 1
1117
0.4
chr1_47180812_47180963 1.05 EFCAB14
EF-hand calcium binding domain 14
3849
0.2
chr1_17572036_17572187 1.04 PADI3
peptidyl arginine deiminase, type III
3482
0.2
chr4_111106837_111106988 1.03 ELOVL6
ELOVL fatty acid elongase 6
12897
0.25
chr20_24387722_24387873 1.01 SYNDIG1
synapse differentiation inducing 1
62038
0.15
chr8_81785077_81785279 1.00 ZNF704
zinc finger protein 704
722
0.78
chr12_95071507_95071838 0.98 TMCC3
transmembrane and coiled-coil domain family 3
27334
0.23
chr19_40596172_40596384 0.98 ZNF780A
zinc finger protein 780A
86
0.82
chr2_34257_34408 0.97 FAM110C
family with sequence similarity 110, member C
12053
0.3
chr6_86175199_86175350 0.97 NT5E
5'-nucleotidase, ecto (CD73)
5825
0.29
chr1_159915900_159916142 0.95 IGSF9
immunoglobulin superfamily, member 9
635
0.57
chr6_159224800_159225738 0.95 EZR-AS1
EZR antisense RNA 1
13774
0.17
chr2_120041441_120041676 0.91 STEAP3-AS1
STEAP3 antisense RNA 1
34911
0.15
chr11_126235331_126235482 0.90 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
9537
0.16
chr5_55786776_55786927 0.90 CTC-236F12.4
Uncharacterized protein
9255
0.21
chr18_60499710_60499861 0.90 AC015989.2

6163
0.22
chr11_110066760_110066911 0.88 RDX
radixin
41776
0.19
chr17_34880270_34880421 0.88 MYO19
myosin XIX
9701
0.12
chr20_50104752_50104903 0.87 ENSG00000266761
.
35313
0.19
chr11_126252609_126252760 0.87 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
9386
0.18
chr10_91217956_91218107 0.87 RP11-168O10.6

2210
0.28
chr8_126239012_126239417 0.87 ENSG00000242170
.
43632
0.17
chr7_22473312_22473463 0.87 ENSG00000263927
.
53764
0.13
chr1_114888962_114889116 0.87 TRIM33
tripartite motif containing 33
116819
0.06
chr14_61993184_61993433 0.87 RP11-47I22.4

2538
0.3
chr6_18425072_18425223 0.86 ENSG00000238458
.
22864
0.21
chr10_119169187_119169338 0.85 PDZD8
PDZ domain containing 8
34284
0.17
chr1_36040729_36040916 0.85 RP4-728D4.2

1474
0.29
chr17_70412226_70412377 0.85 ENSG00000200783
.
247990
0.02
chr1_174935228_174935449 0.84 RABGAP1L
RAB GTPase activating protein 1-like
1433
0.35
chr2_12695125_12695442 0.84 ENSG00000207183
.
143656
0.05
chr12_92790516_92790729 0.83 RP11-693J15.4

24685
0.17
chr1_115781808_115781959 0.82 RP4-663N10.1

43772
0.18
chr4_40911168_40911319 0.82 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
15954
0.2
chr16_84390290_84390441 0.82 ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
11768
0.18
chr8_81665687_81665939 0.82 ENSG00000212429
.
3885
0.28
chr16_67960353_67960504 0.81 CTRL
chymotrypsin-like
5337
0.09
chr6_167426333_167426484 0.81 FGFR1OP
FGFR1 oncogene partner
13512
0.14
chr10_50626953_50627104 0.80 RP11-123B3.2

295
0.91
chr6_108496924_108497159 0.80 NR2E1
nuclear receptor subfamily 2, group E, member 1
7074
0.18
chr21_43612405_43612556 0.80 ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
7319
0.2
chr3_193509513_193509757 0.80 ENSG00000243991
.
51125
0.16
chr17_79485610_79485838 0.80 RP13-766D20.2

342
0.76
chr9_22104098_22104249 0.79 CDKN2B-AS1
CDKN2B antisense RNA 1
9504
0.26
chr15_93592088_93592239 0.79 RGMA
repulsive guidance molecule family member a
24211
0.21
chr14_59788218_59788466 0.79 DAAM1
dishevelled associated activator of morphogenesis 1
58169
0.14
chr12_11883141_11883434 0.78 ETV6
ets variant 6
22148
0.26
chr16_3012791_3012942 0.78 KREMEN2
kringle containing transmembrane protein 2
1079
0.26
chr16_75130684_75130883 0.78 ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
7899
0.16
chr13_50932016_50932167 0.78 ENSG00000221198
.
5282
0.33
chr10_75815480_75815698 0.77 VCL
vinculin
27645
0.17
chr4_101351551_101351881 0.77 EMCN
endomucin
44518
0.2
chr16_85678818_85679245 0.76 GSE1
Gse1 coiled-coil protein
9007
0.17
chr9_71737791_71737961 0.76 TJP2
tight junction protein 2
1652
0.48
chr19_54982368_54982633 0.75 CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
1911
0.17
chr3_150461183_150461334 0.75 SIAH2-AS1
SIAH2 antisense RNA 1
18466
0.15
chr11_95829326_95829477 0.75 MTMR2
myotubularin related protein 2
171942
0.03
chr4_27031264_27031415 0.75 STIM2
stromal interaction molecule 2
21244
0.28
chr11_71783035_71783766 0.75 ENSG00000263742
.
52
0.94
chr2_213642051_213642202 0.75 ENSG00000221388
.
13727
0.3
chr9_518186_518337 0.75 ENSG00000264949
.
10708
0.14
chr3_87367935_87368086 0.73 POU1F1
POU class 1 homeobox 1
42273
0.19
chr17_19099525_19099830 0.73 ENSG00000264940
.
6119
0.1
chr1_202349043_202349194 0.73 ENSG00000272262
.
30217
0.15
chrX_7050343_7050602 0.73 ENSG00000264268
.
15429
0.23
chr8_102449532_102449683 0.72 ENSG00000239211
.
39446
0.16
chr18_52497228_52497379 0.72 RAB27B
RAB27B, member RAS oncogene family
1873
0.45
chr7_2549187_2549338 0.72 LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
2901
0.22
chr15_93365955_93366117 0.72 FAM174B
family with sequence similarity 174, member B
13008
0.16
chr4_154388689_154389189 0.72 KIAA0922
KIAA0922
1438
0.51
chr11_14375636_14375787 0.72 RRAS2
related RAS viral (r-ras) oncogene homolog 2
335
0.93
chr13_50160162_50160384 0.71 RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
554
0.8
chr12_67355263_67355414 0.71 GRIP1
glutamate receptor interacting protein 1
157372
0.04
chr17_4711269_4711435 0.71 PLD2
phospholipase D2
495
0.61
chr17_35974821_35975108 0.71 RP11-697E22.1

5177
0.17
chr7_116167296_116167447 0.70 CAV1
caveolin 1, caveolae protein, 22kDa
1024
0.48
chr2_191183153_191183456 0.70 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
1312
0.49
chr1_209816372_209816523 0.70 LAMB3
laminin, beta 3
8232
0.15
chr17_79787756_79787907 0.70 FAM195B
family with sequence similarity 195, member B
3287
0.09
chr1_25894144_25894295 0.70 LDLRAP1
low density lipoprotein receptor adaptor protein 1
24148
0.17
chr2_61897669_61897960 0.69 ENSG00000206973
.
65063
0.12
chr21_16242942_16243093 0.69 AF127577.8

47838
0.16
chr9_27634943_27635114 0.69 C9orf72
chromosome 9 open reading frame 72
61164
0.14
chr9_6133801_6133990 0.69 IL33
interleukin 33
81910
0.09
chr1_228280825_228280976 0.69 ENSG00000264944
.
4064
0.14
chr8_62008130_62008281 0.69 CLVS1
clavesin 1
38488
0.22
chr19_12405667_12405818 0.69 ZNF44
zinc finger protein 44
40
0.97
chr12_25921695_25921846 0.68 ENSG00000222950
.
10733
0.28
chr12_14537097_14537641 0.68 ATF7IP
activating transcription factor 7 interacting protein
629
0.79
chr6_37103887_37104038 0.68 PIM1
pim-1 oncogene
34017
0.15
chr17_25833827_25833978 0.68 KSR1
kinase suppressor of ras 1
34866
0.16
chr4_111283130_111283281 0.68 ENSG00000199894
.
71139
0.11
chr6_18053935_18054086 0.67 KIF13A
kinesin family member 13A
66156
0.11
chr2_242209688_242209941 0.67 HDLBP
high density lipoprotein binding protein
1572
0.31
chr16_81222783_81222934 0.67 PKD1L2
polycystic kidney disease 1-like 2
7924
0.19
chr16_68268270_68268421 0.66 ESRP2
epithelial splicing regulatory protein 2
1690
0.16
chr15_99206334_99206549 0.66 IGF1R
insulin-like growth factor 1 receptor
14168
0.22
chr1_32135277_32135428 0.66 COL16A1
collagen, type XVI, alpha 1
3670
0.16
chr10_127941521_127941672 0.65 ENSG00000222740
.
107445
0.07
chr8_37403860_37404011 0.65 RP11-150O12.6

29396
0.2
chr21_46493345_46493835 0.65 AP001579.1
Uncharacterized protein
663
0.49
chr11_61463037_61463336 0.65 DAGLA
diacylglycerol lipase, alpha
15281
0.16
chr10_99168304_99168455 0.65 RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
7252
0.1
chr6_73839968_73840119 0.65 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
9763
0.19
chr6_168436215_168436366 0.65 KIF25
kinesin family member 25
1612
0.45
chr12_123187557_123187708 0.64 HCAR2
hydroxycarboxylic acid receptor 2
258
0.9
chr4_170333365_170333516 0.64 SH3RF1
SH3 domain containing ring finger 1
141184
0.05
chr1_115612637_115613031 0.64 TSPAN2
tetraspanin 2
19201
0.23
chr4_177760307_177760458 0.64 VEGFC
vascular endothelial growth factor C
46501
0.2
chr17_4542217_4542549 0.63 ALOX15
arachidonate 15-lipoxygenase
794
0.48
chr2_109236323_109236550 0.63 LIMS1
LIM and senescent cell antigen-like domains 1
1286
0.53
chr4_154004111_154004403 0.63 TRIM2
tripartite motif containing 2
69388
0.12
chr1_68611188_68611339 0.63 GNG12-AS1
GNG12 antisense RNA 1
7223
0.23
chr9_37084008_37084159 0.62 RP11-220I1.2

31404
0.15
chr5_118703141_118703501 0.62 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
11591
0.21
chr12_104194037_104194232 0.62 RP11-650K20.2

19254
0.13
chr7_155526567_155526809 0.62 RBM33
RNA binding motif protein 33
12425
0.24
chr8_56826165_56826541 0.61 ENSG00000216204
.
4833
0.16
chr11_119230682_119230833 0.61 USP2
ubiquitin specific peptidase 2
4160
0.1
chr19_19706143_19706366 0.61 AC002306.1

10905
0.12
chr17_74496103_74496254 0.61 RHBDF2
rhomboid 5 homolog 2 (Drosophila)
1275
0.29
chr17_19085056_19085346 0.60 ENSG00000263934
.
6128
0.09
chr19_6236985_6237136 0.60 CTC-503J8.4

22108
0.13
chr3_67022512_67022756 0.60 KBTBD8
kelch repeat and BTB (POZ) domain containing 8
26093
0.28
chr5_148926631_148926856 0.60 CSNK1A1
casein kinase 1, alpha 1
3119
0.21
chr7_150450811_150450962 0.60 GIMAP5
GTPase, IMAP family member 5
16450
0.15
chr5_11903259_11903410 0.59 CTNND2
catenin (cadherin-associated protein), delta 2
20
0.99
chr20_50177544_50177792 0.59 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
1500
0.54
chr1_9144622_9144884 0.59 ENSG00000252404
.
1998
0.27
chr5_1793158_1793909 0.59 MRPL36
mitochondrial ribosomal protein L36
6331
0.19
chr2_38920217_38920368 0.59 GALM
galactose mutarotase (aldose 1-epimerase)
11855
0.17
chr19_13273549_13273700 0.58 CTC-250I14.6

8617
0.11
chr16_57300234_57300438 0.58 PLLP
plasmolipin
3053
0.17
chr3_37326827_37326996 0.58 GOLGA4
golgin A4
3237
0.25
chr14_34801203_34801354 0.58 EGLN3
egl-9 family hypoxia-inducible factor 3
109195
0.06
chr2_31450999_31451150 0.58 ENSG00000201671
.
104
0.97
chr14_52332743_52333227 0.58 GNG2
guanine nucleotide binding protein (G protein), gamma 2
4943
0.23
chr12_64798932_64799366 0.58 XPOT
exportin, tRNA
323
0.88
chr18_39534789_39534940 0.58 PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
307
0.95
chr10_106077859_106078132 0.58 RP11-127L20.5

6096
0.14
chr6_76462249_76462400 0.58 MYO6
myosin VI
3275
0.25
chr2_102091009_102091179 0.57 RFX8
RFX family member 8, lacking RFX DNA binding domain
71
0.98
chr11_77113463_77113614 0.57 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
9411
0.24
chr12_44201145_44201617 0.57 TWF1
twinfilin actin-binding protein 1
1203
0.49
chr16_74483930_74484081 0.56 ENSG00000251794
.
6434
0.16
chr6_71109282_71109433 0.56 FAM135A
family with sequence similarity 135, member A
13654
0.21
chr17_18973507_18973758 0.56 ENSG00000262074
.
6183
0.11
chr14_104583310_104583461 0.56 ENSG00000207568
.
357
0.84
chr8_22014494_22014879 0.56 LGI3
leucine-rich repeat LGI family, member 3
89
0.94
chr15_62598892_62599117 0.56 RP11-299H22.5

36125
0.17
chr11_70333823_70333974 0.56 AP001271.3

10201
0.17
chr10_126410305_126410507 0.56 FAM53B-AS1
FAM53B antisense RNA 1
17653
0.16
chr1_14087288_14087439 0.56 PRDM2
PR domain containing 2, with ZNF domain
10858
0.25
chr16_68670601_68670752 0.55 ENSG00000252640
.
5805
0.13
chr3_119807499_119807666 0.55 GSK3B
glycogen synthase kinase 3 beta
4931
0.22
chr11_123325382_123325669 0.55 AP000783.1
Uncharacterized protein
24467
0.2
chrX_30918576_30918727 0.55 TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
33332
0.17
chr9_21546893_21547044 0.55 MIR31HG
MIR31 host gene (non-protein coding)
12700
0.16
chr1_2347801_2347952 0.55 PEX10
peroxisomal biogenesis factor 10
2640
0.15
chr1_100169867_100170018 0.55 PALMD
palmdelphin
58193
0.11
chr8_103664408_103664722 0.55 KLF10
Kruppel-like factor 10
2038
0.38
chr12_62671051_62671202 0.54 USP15
ubiquitin specific peptidase 15
1283
0.49
chr6_6800951_6801164 0.54 ENSG00000240936
.
138073
0.05
chr2_181970504_181970655 0.54 UBE2E3
ubiquitin-conjugating enzyme E2E 3
123829
0.06
chr3_185276204_185276355 0.54 LIPH
lipase, member H
5878
0.22
chr12_120667953_120668326 0.54 PXN
paxillin
3492
0.15
chr9_127030175_127030580 0.53 RP11-121A14.3

5222
0.19
chr3_32861161_32861312 0.53 TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
1726
0.45
chr9_116364960_116365111 0.53 RGS3
regulator of G-protein signaling 3
9269
0.22
chr11_119038916_119039214 0.53 NLRX1
NLR family member X1
19
0.95
chr2_192167664_192167815 0.53 MYO1B
myosin IB
26128
0.22
chr10_102270443_102270627 0.53 SEC31B
SEC31 homolog B (S. cerevisiae)
9056
0.16
chr6_50788742_50788893 0.53 TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
2378
0.45
chr6_110081297_110081448 0.52 FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
6560
0.28
chr6_2542347_2542580 0.52 C6orf195
chromosome 6 open reading frame 195
92374
0.09
chr22_20868530_20868681 0.52 MED15
mediator complex subunit 15
6261
0.11
chr15_58896636_58896787 0.52 ENSG00000239100
.
4277
0.22
chr1_234862986_234863275 0.52 ENSG00000201638
.
110590
0.06
chr5_157340123_157340274 0.52 CLINT1
clathrin interactor 1
54015
0.13
chr5_139702813_139703249 0.52 PFDN1
prefoldin subunit 1
20325
0.11
chr1_178314482_178314633 0.52 RASAL2
RAS protein activator like 2
3951
0.34
chr1_89727484_89727635 0.52 RP4-620F22.2

1294
0.45
chr4_26344038_26344485 0.52 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
501
0.88
chr9_132514460_132514833 0.52 PTGES
prostaglandin E synthase
680
0.65
chr19_43959930_43960130 0.52 LYPD3
LY6/PLAUR domain containing 3
9782
0.14
chr15_99401134_99401285 0.52 IGF1R
insulin-like growth factor 1 receptor
32361
0.17
chr3_44690178_44690339 0.51 ZNF35
zinc finger protein 35
21
0.97
chr18_54128502_54128653 0.51 TXNL1
thioredoxin-like 1
153145
0.04
chr10_3929538_3929752 0.51 KLF6
Kruppel-like factor 6
102172
0.08
chr9_130396397_130396548 0.51 STXBP1
syntaxin binding protein 1
21904
0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of GRHL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.3 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.3 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.1 0.5 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.4 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.1 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.3 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.2 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.3 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 1.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.1 GO:0032261 purine nucleotide salvage(GO:0032261)
0.1 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095) negative regulation of helicase activity(GO:0051097)
0.0 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0003171 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:1903504 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.7 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.3 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0002248 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0071333 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0098868 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.1 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.0 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0046036 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0032372 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.0 GO:0060192 negative regulation of lipase activity(GO:0060192)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.3 GO:0007569 cell aging(GO:0007569)
0.0 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.0 0.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0035121 obsolete tail morphogenesis(GO:0035121)
0.0 0.3 GO:0042311 vasodilation(GO:0042311)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0016358 dendrite development(GO:0016358)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 1.9 GO:0005912 adherens junction(GO:0005912)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.5 GO:0052742 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol kinase activity(GO:0052742)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0046527 UDP-glucosyltransferase activity(GO:0035251) glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.0 0.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.0 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling