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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GRHL1

Z-value: 2.41

Motif logo

Transcription factors associated with GRHL1

Gene Symbol	Gene ID	Gene Info
GRHL1 Ensembl NCBI GeneCards UniProt	ENSG00000134317.13	GRHL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GRHL1	chr2_10120083_10120407	15189	0.161474	-0.72	2.8e-02	Click!
GRHL1	chr2_10106881_10107032	15129	0.174178	-0.68	4.5e-02	Click!
GRHL1	chr2_10122799_10122950	12560	0.163663	-0.63	7.0e-02	Click!
GRHL1	chr2_10109337_10109488	17585	0.167183	-0.56	1.2e-01	Click!
GRHL1	chr2_10081034_10081185	4232	0.239220	0.55	1.2e-01	Click!

Activity of the GRHL1 motif across conditions

Conditions sorted by the z-value of the GRHL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_101882560_101882711	2.01	ZPLD1	zona pellucida-like domain containing 1	64547	0.14
chr9_78830303_78830575	1.31	PCSK5	proprotein convertase subtilisin/kexin type 5	26884	0.26
chrX_2815646_2815988	1.25	ARSD-AS1	ARSD antisense RNA 1	7128	0.17
chr2_150023630_150023914	1.19	LYPD6B	LY6/PLAUR domain containing 6B	6782	0.33
chr10_11629983_11630134	1.15	USP6NL	USP6 N-terminal like	14218	0.23
chr8_28558220_28558688	1.15	EXTL3-AS1	EXTL3 antisense RNA 1	316	0.56
chr3_128444618_128444816	1.14	RAB7A	RAB7A, member RAS oncogene family	248	0.92
chr11_8742901_8743052	1.13	ST5	suppression of tumorigenicity 5	2286	0.2
chr10_31321539_31321725	1.11	ZNF438	zinc finger protein 438	766	0.74
chr1_209492900_209493051	1.08	ENSG00000230937	.	112503	0.07
chr12_48148703_48148929	1.06	SLC48A1	solute carrier family 48 (heme transporter), member 1	1117	0.4
chr1_47180812_47180963	1.05	EFCAB14	EF-hand calcium binding domain 14	3849	0.2
chr1_17572036_17572187	1.04	PADI3	peptidyl arginine deiminase, type III	3482	0.2
chr4_111106837_111106988	1.03	ELOVL6	ELOVL fatty acid elongase 6	12897	0.25
chr20_24387722_24387873	1.01	SYNDIG1	synapse differentiation inducing 1	62038	0.15
chr8_81785077_81785279	1.00	ZNF704	zinc finger protein 704	722	0.78
chr12_95071507_95071838	0.98	TMCC3	transmembrane and coiled-coil domain family 3	27334	0.23
chr19_40596172_40596384	0.98	ZNF780A	zinc finger protein 780A	86	0.82
chr2_34257_34408	0.97	FAM110C	family with sequence similarity 110, member C	12053	0.3
chr6_86175199_86175350	0.97	NT5E	5'-nucleotidase, ecto (CD73)	5825	0.29
chr1_159915900_159916142	0.95	IGSF9	immunoglobulin superfamily, member 9	635	0.57
chr6_159224800_159225738	0.95	EZR-AS1	EZR antisense RNA 1	13774	0.17
chr2_120041441_120041676	0.91	STEAP3-AS1	STEAP3 antisense RNA 1	34911	0.15
chr11_126235331_126235482	0.90	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	9537	0.16
chr5_55786776_55786927	0.90	CTC-236F12.4	Uncharacterized protein	9255	0.21
chr18_60499710_60499861	0.90	AC015989.2		6163	0.22
chr11_110066760_110066911	0.88	RDX	radixin	41776	0.19
chr17_34880270_34880421	0.88	MYO19	myosin XIX	9701	0.12
chr20_50104752_50104903	0.87	ENSG00000266761	.	35313	0.19
chr11_126252609_126252760	0.87	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	9386	0.18
chr10_91217956_91218107	0.87	RP11-168O10.6		2210	0.28
chr8_126239012_126239417	0.87	ENSG00000242170	.	43632	0.17
chr7_22473312_22473463	0.87	ENSG00000263927	.	53764	0.13
chr1_114888962_114889116	0.87	TRIM33	tripartite motif containing 33	116819	0.06
chr14_61993184_61993433	0.87	RP11-47I22.4		2538	0.3
chr6_18425072_18425223	0.86	ENSG00000238458	.	22864	0.21
chr10_119169187_119169338	0.85	PDZD8	PDZ domain containing 8	34284	0.17
chr1_36040729_36040916	0.85	RP4-728D4.2		1474	0.29
chr17_70412226_70412377	0.85	ENSG00000200783	.	247990	0.02
chr1_174935228_174935449	0.84	RABGAP1L	RAB GTPase activating protein 1-like	1433	0.35
chr2_12695125_12695442	0.84	ENSG00000207183	.	143656	0.05
chr12_92790516_92790729	0.83	RP11-693J15.4		24685	0.17
chr1_115781808_115781959	0.82	RP4-663N10.1		43772	0.18
chr4_40911168_40911319	0.82	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	15954	0.2
chr16_84390290_84390441	0.82	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	11768	0.18
chr8_81665687_81665939	0.82	ENSG00000212429	.	3885	0.28
chr16_67960353_67960504	0.81	CTRL	chymotrypsin-like	5337	0.09
chr6_167426333_167426484	0.81	FGFR1OP	FGFR1 oncogene partner	13512	0.14
chr10_50626953_50627104	0.80	RP11-123B3.2		295	0.91
chr6_108496924_108497159	0.80	NR2E1	nuclear receptor subfamily 2, group E, member 1	7074	0.18
chr21_43612405_43612556	0.80	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	7319	0.2
chr3_193509513_193509757	0.80	ENSG00000243991	.	51125	0.16
chr17_79485610_79485838	0.80	RP13-766D20.2		342	0.76
chr9_22104098_22104249	0.79	CDKN2B-AS1	CDKN2B antisense RNA 1	9504	0.26
chr15_93592088_93592239	0.79	RGMA	repulsive guidance molecule family member a	24211	0.21
chr14_59788218_59788466	0.79	DAAM1	dishevelled associated activator of morphogenesis 1	58169	0.14
chr12_11883141_11883434	0.78	ETV6	ets variant 6	22148	0.26
chr16_3012791_3012942	0.78	KREMEN2	kringle containing transmembrane protein 2	1079	0.26
chr16_75130684_75130883	0.78	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	7899	0.16
chr13_50932016_50932167	0.78	ENSG00000221198	.	5282	0.33
chr10_75815480_75815698	0.77	VCL	vinculin	27645	0.17
chr4_101351551_101351881	0.77	EMCN	endomucin	44518	0.2
chr16_85678818_85679245	0.76	GSE1	Gse1 coiled-coil protein	9007	0.17
chr9_71737791_71737961	0.76	TJP2	tight junction protein 2	1652	0.48
chr19_54982368_54982633	0.75	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5	1911	0.17
chr3_150461183_150461334	0.75	SIAH2-AS1	SIAH2 antisense RNA 1	18466	0.15
chr11_95829326_95829477	0.75	MTMR2	myotubularin related protein 2	171942	0.03
chr4_27031264_27031415	0.75	STIM2	stromal interaction molecule 2	21244	0.28
chr11_71783035_71783766	0.75	ENSG00000263742	.	52	0.94
chr2_213642051_213642202	0.75	ENSG00000221388	.	13727	0.3
chr9_518186_518337	0.75	ENSG00000264949	.	10708	0.14
chr3_87367935_87368086	0.73	POU1F1	POU class 1 homeobox 1	42273	0.19
chr17_19099525_19099830	0.73	ENSG00000264940	.	6119	0.1
chr1_202349043_202349194	0.73	ENSG00000272262	.	30217	0.15
chrX_7050343_7050602	0.73	ENSG00000264268	.	15429	0.23
chr8_102449532_102449683	0.72	ENSG00000239211	.	39446	0.16
chr18_52497228_52497379	0.72	RAB27B	RAB27B, member RAS oncogene family	1873	0.45
chr7_2549187_2549338	0.72	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	2901	0.22
chr15_93365955_93366117	0.72	FAM174B	family with sequence similarity 174, member B	13008	0.16
chr4_154388689_154389189	0.72	KIAA0922	KIAA0922	1438	0.51
chr11_14375636_14375787	0.72	RRAS2	related RAS viral (r-ras) oncogene homolog 2	335	0.93
chr13_50160162_50160384	0.71	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	554	0.8
chr12_67355263_67355414	0.71	GRIP1	glutamate receptor interacting protein 1	157372	0.04
chr17_4711269_4711435	0.71	PLD2	phospholipase D2	495	0.61
chr17_35974821_35975108	0.71	RP11-697E22.1		5177	0.17
chr7_116167296_116167447	0.70	CAV1	caveolin 1, caveolae protein, 22kDa	1024	0.48
chr2_191183153_191183456	0.70	HIBCH	3-hydroxyisobutyryl-CoA hydrolase	1312	0.49
chr1_209816372_209816523	0.70	LAMB3	laminin, beta 3	8232	0.15
chr17_79787756_79787907	0.70	FAM195B	family with sequence similarity 195, member B	3287	0.09
chr1_25894144_25894295	0.70	LDLRAP1	low density lipoprotein receptor adaptor protein 1	24148	0.17
chr2_61897669_61897960	0.69	ENSG00000206973	.	65063	0.12
chr21_16242942_16243093	0.69	AF127577.8		47838	0.16
chr9_27634943_27635114	0.69	C9orf72	chromosome 9 open reading frame 72	61164	0.14
chr9_6133801_6133990	0.69	IL33	interleukin 33	81910	0.09
chr1_228280825_228280976	0.69	ENSG00000264944	.	4064	0.14
chr8_62008130_62008281	0.69	CLVS1	clavesin 1	38488	0.22
chr19_12405667_12405818	0.69	ZNF44	zinc finger protein 44	40	0.97
chr12_25921695_25921846	0.68	ENSG00000222950	.	10733	0.28
chr12_14537097_14537641	0.68	ATF7IP	activating transcription factor 7 interacting protein	629	0.79
chr6_37103887_37104038	0.68	PIM1	pim-1 oncogene	34017	0.15
chr17_25833827_25833978	0.68	KSR1	kinase suppressor of ras 1	34866	0.16
chr4_111283130_111283281	0.68	ENSG00000199894	.	71139	0.11
chr6_18053935_18054086	0.67	KIF13A	kinesin family member 13A	66156	0.11
chr2_242209688_242209941	0.67	HDLBP	high density lipoprotein binding protein	1572	0.31
chr16_81222783_81222934	0.67	PKD1L2	polycystic kidney disease 1-like 2	7924	0.19
chr16_68268270_68268421	0.66	ESRP2	epithelial splicing regulatory protein 2	1690	0.16
chr15_99206334_99206549	0.66	IGF1R	insulin-like growth factor 1 receptor	14168	0.22
chr1_32135277_32135428	0.66	COL16A1	collagen, type XVI, alpha 1	3670	0.16
chr10_127941521_127941672	0.65	ENSG00000222740	.	107445	0.07
chr8_37403860_37404011	0.65	RP11-150O12.6		29396	0.2
chr21_46493345_46493835	0.65	AP001579.1	Uncharacterized protein	663	0.49
chr11_61463037_61463336	0.65	DAGLA	diacylglycerol lipase, alpha	15281	0.16
chr10_99168304_99168455	0.65	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	7252	0.1
chr6_73839968_73840119	0.65	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	9763	0.19
chr6_168436215_168436366	0.65	KIF25	kinesin family member 25	1612	0.45
chr12_123187557_123187708	0.64	HCAR2	hydroxycarboxylic acid receptor 2	258	0.9
chr4_170333365_170333516	0.64	SH3RF1	SH3 domain containing ring finger 1	141184	0.05
chr1_115612637_115613031	0.64	TSPAN2	tetraspanin 2	19201	0.23
chr4_177760307_177760458	0.64	VEGFC	vascular endothelial growth factor C	46501	0.2
chr17_4542217_4542549	0.63	ALOX15	arachidonate 15-lipoxygenase	794	0.48
chr2_109236323_109236550	0.63	LIMS1	LIM and senescent cell antigen-like domains 1	1286	0.53
chr4_154004111_154004403	0.63	TRIM2	tripartite motif containing 2	69388	0.12
chr1_68611188_68611339	0.63	GNG12-AS1	GNG12 antisense RNA 1	7223	0.23
chr9_37084008_37084159	0.62	RP11-220I1.2		31404	0.15
chr5_118703141_118703501	0.62	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	11591	0.21
chr12_104194037_104194232	0.62	RP11-650K20.2		19254	0.13
chr7_155526567_155526809	0.62	RBM33	RNA binding motif protein 33	12425	0.24
chr8_56826165_56826541	0.61	ENSG00000216204	.	4833	0.16
chr11_119230682_119230833	0.61	USP2	ubiquitin specific peptidase 2	4160	0.1
chr19_19706143_19706366	0.61	AC002306.1		10905	0.12
chr17_74496103_74496254	0.61	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	1275	0.29
chr17_19085056_19085346	0.60	ENSG00000263934	.	6128	0.09
chr19_6236985_6237136	0.60	CTC-503J8.4		22108	0.13
chr3_67022512_67022756	0.60	KBTBD8	kelch repeat and BTB (POZ) domain containing 8	26093	0.28
chr5_148926631_148926856	0.60	CSNK1A1	casein kinase 1, alpha 1	3119	0.21
chr7_150450811_150450962	0.60	GIMAP5	GTPase, IMAP family member 5	16450	0.15
chr5_11903259_11903410	0.59	CTNND2	catenin (cadherin-associated protein), delta 2	20	0.99
chr20_50177544_50177792	0.59	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	1500	0.54
chr1_9144622_9144884	0.59	ENSG00000252404	.	1998	0.27
chr5_1793158_1793909	0.59	MRPL36	mitochondrial ribosomal protein L36	6331	0.19
chr2_38920217_38920368	0.59	GALM	galactose mutarotase (aldose 1-epimerase)	11855	0.17
chr19_13273549_13273700	0.58	CTC-250I14.6		8617	0.11
chr16_57300234_57300438	0.58	PLLP	plasmolipin	3053	0.17
chr3_37326827_37326996	0.58	GOLGA4	golgin A4	3237	0.25
chr14_34801203_34801354	0.58	EGLN3	egl-9 family hypoxia-inducible factor 3	109195	0.06
chr2_31450999_31451150	0.58	ENSG00000201671	.	104	0.97
chr14_52332743_52333227	0.58	GNG2	guanine nucleotide binding protein (G protein), gamma 2	4943	0.23
chr12_64798932_64799366	0.58	XPOT	exportin, tRNA	323	0.88
chr18_39534789_39534940	0.58	PIK3C3	phosphatidylinositol 3-kinase, catalytic subunit type 3	307	0.95
chr10_106077859_106078132	0.58	RP11-127L20.5		6096	0.14
chr6_76462249_76462400	0.58	MYO6	myosin VI	3275	0.25
chr2_102091009_102091179	0.57	RFX8	RFX family member 8, lacking RFX DNA binding domain	71	0.98
chr11_77113463_77113614	0.57	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	9411	0.24
chr12_44201145_44201617	0.57	TWF1	twinfilin actin-binding protein 1	1203	0.49
chr16_74483930_74484081	0.56	ENSG00000251794	.	6434	0.16
chr6_71109282_71109433	0.56	FAM135A	family with sequence similarity 135, member A	13654	0.21
chr17_18973507_18973758	0.56	ENSG00000262074	.	6183	0.11
chr14_104583310_104583461	0.56	ENSG00000207568	.	357	0.84
chr8_22014494_22014879	0.56	LGI3	leucine-rich repeat LGI family, member 3	89	0.94
chr15_62598892_62599117	0.56	RP11-299H22.5		36125	0.17
chr11_70333823_70333974	0.56	AP001271.3		10201	0.17
chr10_126410305_126410507	0.56	FAM53B-AS1	FAM53B antisense RNA 1	17653	0.16
chr1_14087288_14087439	0.56	PRDM2	PR domain containing 2, with ZNF domain	10858	0.25
chr16_68670601_68670752	0.55	ENSG00000252640	.	5805	0.13
chr3_119807499_119807666	0.55	GSK3B	glycogen synthase kinase 3 beta	4931	0.22
chr11_123325382_123325669	0.55	AP000783.1	Uncharacterized protein	24467	0.2
chrX_30918576_30918727	0.55	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	33332	0.17
chr9_21546893_21547044	0.55	MIR31HG	MIR31 host gene (non-protein coding)	12700	0.16
chr1_2347801_2347952	0.55	PEX10	peroxisomal biogenesis factor 10	2640	0.15
chr1_100169867_100170018	0.55	PALMD	palmdelphin	58193	0.11
chr8_103664408_103664722	0.55	KLF10	Kruppel-like factor 10	2038	0.38
chr12_62671051_62671202	0.54	USP15	ubiquitin specific peptidase 15	1283	0.49
chr6_6800951_6801164	0.54	ENSG00000240936	.	138073	0.05
chr2_181970504_181970655	0.54	UBE2E3	ubiquitin-conjugating enzyme E2E 3	123829	0.06
chr3_185276204_185276355	0.54	LIPH	lipase, member H	5878	0.22
chr12_120667953_120668326	0.54	PXN	paxillin	3492	0.15
chr9_127030175_127030580	0.53	RP11-121A14.3		5222	0.19
chr3_32861161_32861312	0.53	TRIM71	tripartite motif containing 71, E3 ubiquitin protein ligase	1726	0.45
chr9_116364960_116365111	0.53	RGS3	regulator of G-protein signaling 3	9269	0.22
chr11_119038916_119039214	0.53	NLRX1	NLR family member X1	19	0.95
chr2_192167664_192167815	0.53	MYO1B	myosin IB	26128	0.22
chr10_102270443_102270627	0.53	SEC31B	SEC31 homolog B (S. cerevisiae)	9056	0.16
chr6_50788742_50788893	0.53	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	2378	0.45
chr6_110081297_110081448	0.52	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	6560	0.28
chr6_2542347_2542580	0.52	C6orf195	chromosome 6 open reading frame 195	92374	0.09
chr22_20868530_20868681	0.52	MED15	mediator complex subunit 15	6261	0.11
chr15_58896636_58896787	0.52	ENSG00000239100	.	4277	0.22
chr1_234862986_234863275	0.52	ENSG00000201638	.	110590	0.06
chr5_157340123_157340274	0.52	CLINT1	clathrin interactor 1	54015	0.13
chr5_139702813_139703249	0.52	PFDN1	prefoldin subunit 1	20325	0.11
chr1_178314482_178314633	0.52	RASAL2	RAS protein activator like 2	3951	0.34
chr1_89727484_89727635	0.52	RP4-620F22.2		1294	0.45
chr4_26344038_26344485	0.52	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	501	0.88
chr9_132514460_132514833	0.52	PTGES	prostaglandin E synthase	680	0.65
chr19_43959930_43960130	0.52	LYPD3	LY6/PLAUR domain containing 3	9782	0.14
chr15_99401134_99401285	0.52	IGF1R	insulin-like growth factor 1 receptor	32361	0.17
chr3_44690178_44690339	0.51	ZNF35	zinc finger protein 35	21	0.97
chr18_54128502_54128653	0.51	TXNL1	thioredoxin-like 1	153145	0.04
chr10_3929538_3929752	0.51	KLF6	Kruppel-like factor 6	102172	0.08
chr9_130396397_130396548	0.51	STXBP1	syntaxin binding protein 1	21904	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GRHL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101)
0.1	0.4	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.3	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.1	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.3	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.5	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.4	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.2	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.1	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1	0.3	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.2	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.3	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	1.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.1	0.6	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.3	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.2	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.2	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.2	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.6	GO:0007032	endosome organization(GO:0007032)
0.0	0.3	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0003356	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.4	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0048263	determination of dorsal identity(GO:0048263)
0.0	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.3	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.9	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.3	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.3	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.1	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.2	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0051095	regulation of helicase activity(GO:0051095) negative regulation of helicase activity(GO:0051097)
0.0	0.5	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0003171	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.2	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.7	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.3	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.2	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.3	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0002248	wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0009154	purine ribonucleotide catabolic process(GO:0009154)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0071333	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0061316	canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.5	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0098868	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.4	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0009437	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0035094	response to nicotine(GO:0035094)
0.0	0.1	GO:0034435	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0	0.1	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.3	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.0	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0046036	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0030032	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0032372	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.0	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.0	GO:0060192	negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.3	GO:0043928	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.3	GO:0007569	cell aging(GO:0007569)
0.0	0.3	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.1	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.0	0.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.3	GO:0042311	vasodilation(GO:0042311)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.4	GO:0016358	dendrite development(GO:0016358)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0001678	cellular glucose homeostasis(GO:0001678)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	1.0	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	0.4	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.7	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.5	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	1.9	GO:0005912	adherens junction(GO:0005912)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.3	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.3	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.3	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.3	GO:0031013	troponin I binding(GO:0031013)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.2	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.3	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.3	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.5	GO:0052742	1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol kinase activity(GO:0052742)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.5	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.3	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.3	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0046527	UDP-glucosyltransferase activity(GO:0035251) glucosyltransferase activity(GO:0046527)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.5	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.5	GO:0005518	collagen binding(GO:0005518)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.6	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.2	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.3	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.2	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.2	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.3	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.0	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling