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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GSC_GSC2

Z-value: 1.33

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Transcription factors associated with GSC_GSC2

Gene Symbol	Gene ID	Gene Info
GSC Ensembl NCBI GeneCards UniProt	ENSG00000133937.3	GSC
GSC2 Ensembl NCBI GeneCards UniProt	ENSG00000063515.2	GSC2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GSC	chr14_95205498_95205649	30989	0.202484	0.81	8.6e-03	Click!
GSC	chr14_95236567_95236718	80	0.983162	-0.71	3.1e-02	Click!
GSC	chr14_95237974_95238125	1487	0.529948	-0.57	1.1e-01	Click!
GSC	chr14_95205255_95205406	31232	0.201656	0.55	1.2e-01	Click!
GSC	chr14_95235460_95235620	1022	0.660084	0.49	1.8e-01	Click!
GSC2	chr22_19136647_19137197	874	0.433300	-0.70	3.5e-02	Click!
GSC2	chr22_19142720_19142871	4999	0.121362	-0.57	1.1e-01	Click!
GSC2	chr22_19136477_19136628	1244	0.304480	-0.45	2.2e-01	Click!
GSC2	chr22_19136086_19136237	1635	0.231016	-0.23	5.6e-01	Click!
GSC2	chr22_19137289_19137440	432	0.720068	-0.09	8.2e-01	Click!

Activity of the GSC_GSC2 motif across conditions

Conditions sorted by the z-value of the GSC_GSC2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_201426596_201426747	0.99	PHLDA3	pleckstrin homology-like domain, family A, member 3	11641	0.15
chr12_11733022_11733284	0.79	ENSG00000251747	.	33740	0.16
chr2_43152776_43153425	0.77	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	133368	0.05
chr5_148352238_148352777	0.74	RP11-44B19.1		2604	0.3
chr14_69544397_69544681	0.71	ENSG00000206768	.	66131	0.1
chr3_170470237_170470470	0.70	ENSG00000222411	.	89608	0.08
chr14_53301825_53302222	0.70	FERMT2	fermitin family member 2	29216	0.15
chr3_174156335_174156660	0.62	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	2280	0.47
chr9_127162086_127162596	0.60	PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	15377	0.19
chr2_45926277_45926449	0.59	U51244.2		23748	0.22
chr5_159305915_159306327	0.58	ADRA1B	adrenoceptor alpha 1B	37669	0.2
chr4_171593437_171593770	0.57	ENSG00000251961	.	219015	0.02
chr2_162949372_162949523	0.56	DPP4	dipeptidyl-peptidase 4	18395	0.18
chr8_97603049_97603490	0.55	SDC2	syndecan 2	4654	0.31
chr9_14271441_14271727	0.55	NFIB	nuclear factor I/B	36428	0.2
chr1_59481843_59482033	0.54	JUN	jun proto-oncogene	232153	0.02
chr10_31939351_31939502	0.53	ENSG00000222412	.	105638	0.07
chr1_52024489_52024927	0.53	OSBPL9	oxysterol binding protein-like 9	18143	0.15
chr11_111428191_111428342	0.52	LAYN	layilin	15989	0.12
chr1_30185013_30185164	0.52	ENSG00000221126	.	67563	0.14
chr17_73690444_73690713	0.51	SAP30BP	SAP30 binding protein	1952	0.18
chr2_159996739_159997187	0.51	ENSG00000202029	.	113309	0.06
chr1_85805501_85805652	0.51	ENSG00000264380	.	55283	0.09
chr15_46162513_46162674	0.51	SQRDL	sulfide quinone reductase-like (yeast)	187855	0.03
chr1_21478340_21478712	0.51	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	22704	0.19
chr9_117715769_117716310	0.51	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	23342	0.24
chr2_174889480_174890119	0.50	SP3	Sp3 transcription factor	59369	0.15
chr17_30068402_30068553	0.50	ENSG00000202026	.	27705	0.19
chr6_3517760_3517987	0.50	SLC22A23	solute carrier family 22, member 23	60617	0.14
chr9_132096828_132097338	0.49	ENSG00000242281	.	35657	0.16
chr17_40481304_40481455	0.49	STAT5A	signal transducer and activator of transcription 5A	23191	0.11
chr7_47366010_47366161	0.49	TNS3	tensin 3	46169	0.21
chr5_64493902_64494516	0.48	ENSG00000207439	.	75013	0.12
chr15_38288177_38288328	0.48	TMCO5A	transmembrane and coiled-coil domains 5A	60794	0.16
chr9_114727126_114727277	0.48	ENSG00000222356	.	31818	0.15
chr5_39093457_39093608	0.48	AC008964.1		11826	0.23
chr9_16143627_16143778	0.47	C9orf92	chromosome 9 open reading frame 92	72195	0.13
chr4_152666058_152666209	0.47	PET112	PET112 homolog (yeast)	16004	0.24
chr2_43496469_43496754	0.47	AC010883.5		39899	0.17
chr3_120147916_120148067	0.46	FSTL1	follistatin-like 1	21847	0.22
chr8_37783052_37783203	0.46	GOT1L1	glutamic-oxaloacetic transaminase 1-like 1	11204	0.13
chr5_149433185_149433336	0.46	ENSG00000238369	.	24245	0.12
chr3_69813399_69813761	0.46	MITF	microphthalmia-associated transcription factor	618	0.78
chr4_77468211_77468426	0.46	ENSG00000207307	.	14838	0.16
chr22_22109341_22109765	0.46	YPEL1	yippee-like 1 (Drosophila)	19430	0.12
chr18_30500917_30501068	0.46	RP11-680N20.1		33047	0.21
chr5_64500241_64500433	0.45	ENSG00000207439	.	81141	0.11
chr9_73518177_73518328	0.45	TRPM3	transient receptor potential cation channel, subfamily M, member 3	34278	0.22
chr10_3570543_3570694	0.45	RP11-184A2.3		222641	0.02
chr19_47478570_47478952	0.44	ENSG00000252071	.	27215	0.14
chr16_30724842_30725097	0.44	ENSG00000206755	.	3111	0.11
chr12_15785962_15786113	0.44	EPS8	epidermal growth factor receptor pathway substrate 8	29171	0.19
chr9_16795794_16795945	0.44	BNC2	basonuclin 2	36417	0.21
chr10_35021138_35021390	0.44	PARD3	par-3 family cell polarity regulator	82985	0.1
chr8_119017458_119017609	0.44	EXT1	exostosin glycosyltransferase 1	105120	0.08
chr6_43088179_43088500	0.44	PTK7	protein tyrosine kinase 7	9990	0.12
chr14_55242379_55242669	0.44	SAMD4A	sterile alpha motif domain containing 4A	20973	0.23
chr11_131928229_131928481	0.44	RP11-697E14.2		73800	0.12
chr3_170820342_170820493	0.44	ENSG00000207963	.	4131	0.3
chr5_156943457_156943608	0.44	ADAM19	ADAM metallopeptidase domain 19	13702	0.17
chr10_80886709_80887280	0.43	ZMIZ1	zinc finger, MIZ-type containing 1	58202	0.14
chr2_44357819_44358004	0.43	ENSG00000252599	.	24123	0.17
chr9_111396759_111396910	0.43	ACTL7B	actin-like 7B	222405	0.02
chrX_12378398_12378549	0.43	FRMPD4-AS1	FRMPD4 antisense RNA 1	14779	0.29
chr5_98396799_98396950	0.43	ENSG00000200351	.	124423	0.06
chr15_69850349_69850500	0.43	ENSG00000207119	.	99936	0.06
chr16_11098719_11098870	0.43	CLEC16A	C-type lectin domain family 16, member A	60356	0.08
chr12_68141751_68141902	0.43	RP11-335O4.3		77127	0.11
chr11_108786966_108787117	0.42	ENSG00000201243	.	89203	0.1
chr12_66341786_66341937	0.42	RP11-366L20.3		398	0.86
chr5_34487773_34488055	0.42	RAI14	retinoic acid induced 14	168428	0.03
chr20_43988664_43988912	0.42	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)	1789	0.23
chr3_159645626_159645969	0.42	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	60740	0.1
chr2_226928659_226928810	0.42	ENSG00000263363	.	594775	0.0
chr11_130752561_130752712	0.42	SNX19	sorting nexin 19	11133	0.3
chr6_52376418_52376603	0.41	TRAM2	translocation associated membrane protein 2	65203	0.11
chr7_55089353_55089504	0.41	EGFR	epidermal growth factor receptor	2617	0.41
chr2_113470510_113470661	0.41	NT5DC4	5'-nucleotidase domain containing 4	8478	0.2
chr11_111077610_111077761	0.41	C11orf53	chromosome 11 open reading frame 53	49022	0.14
chr5_142286909_142287060	0.41	ARHGAP26	Rho GTPase activating protein 26	97	0.98
chr6_138929947_138930098	0.41	NHSL1	NHS-like 1	36345	0.19
chr17_2082426_2082658	0.41	SMG6	SMG6 nonsense mediated mRNA decay factor	6070	0.13
chr7_100422531_100422682	0.41	EPHB4	EPH receptor B4	2131	0.18
chr4_122712483_122712634	0.41	EXOSC9	exosome component 9	9914	0.16
chr20_1809000_1809151	0.41	SIRPA	signal-regulatory protein alpha	66079	0.11
chr1_157983762_157983913	0.40	KIRREL-IT1	KIRREL intronic transcript 1 (non-protein coding)	11503	0.21
chr5_149886580_149886731	0.40	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	1019	0.53
chr20_33292677_33293239	0.40	TP53INP2	tumor protein p53 inducible nuclear protein 2	419	0.86
chr6_1575312_1575463	0.40	FOXC1	forkhead box C1	35294	0.21
chr20_7821639_7821790	0.40	HAO1	hydroxyacid oxidase (glycolate oxidase) 1	99407	0.08
chr1_26797459_26798053	0.40	HMGN2	high mobility group nucleosomal binding domain 2	1254	0.35
chr6_82041474_82041625	0.40	RP1-300G12.2		203081	0.03
chr3_98613485_98613636	0.39	DCBLD2	discoidin, CUB and LCCL domain containing 2	6455	0.19
chr9_79316323_79316721	0.39	PRUNE2	prune homolog 2 (Drosophila)	8631	0.24
chr1_37937094_37937368	0.39	LINC01137	long intergenic non-protein coding RNA 1137	2781	0.2
chr5_143022321_143022472	0.39	ENSG00000266478	.	37029	0.18
chr7_40619322_40619515	0.39	AC004988.1		32891	0.25
chr2_220554157_220554308	0.39	SLC4A3	solute carrier family 4 (anion exchanger), member 3	58380	0.08
chr2_217180660_217180876	0.39	AC069155.1		12720	0.18
chr7_13920733_13920884	0.39	ETV1	ets variant 1	105258	0.08
chr2_9391597_9391776	0.39	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	44792	0.18
chr1_46650137_46650288	0.39	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	8052	0.12
chr1_211210156_211210307	0.39	KCNH1-IT1	KCNH1 intronic transcript 1 (non-protein coding)	96485	0.08
chr9_37943494_37943645	0.39	ENSG00000251745	.	6804	0.24
chr1_94429653_94429804	0.39	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	47453	0.13
chr10_104387429_104387633	0.39	TRIM8	tripartite motif containing 8	16722	0.16
chr11_130642757_130642947	0.39	C11orf44	chromosome 11 open reading frame 44	100001	0.08
chr17_40568875_40569026	0.39	PTRF	polymerase I and transcript release factor	6585	0.11
chr14_103889997_103890148	0.39	MARK3	MAP/microtubule affinity-regulating kinase 3	37496	0.12
chr6_147234985_147235152	0.38	STXBP5-AS1	STXBP5 antisense RNA 1	1953	0.49
chr3_52205760_52205911	0.38	POC1A	POC1 centriolar protein A	17129	0.12
chr6_35393359_35394053	0.38	FANCE	Fanconi anemia, complementation group E	26432	0.15
chr8_61863719_61864009	0.38	CLVS1	clavesin 1	105853	0.07
chr10_131821141_131821577	0.38	EBF3	early B-cell factor 3	59254	0.15
chr7_151572690_151573025	0.38	PRKAG2-AS1	PRKAG2 antisense RNA 1	1270	0.31
chr5_159969265_159969416	0.38	ENSG00000253522	.	56981	0.1
chr8_119778762_119778913	0.38	SAMD12	sterile alpha motif domain containing 12	144603	0.05
chr1_208396700_208396908	0.38	PLXNA2	plexin A2	20861	0.29
chr11_78511494_78511645	0.38	TENM4	teneurin transmembrane protein 4	4887	0.29
chr2_228741295_228741446	0.37	DAW1	dynein assembly factor with WDR repeat domains 1	4991	0.23
chr16_68333106_68333257	0.37	SLC7A6OS	solute carrier family 7, member 6 opposite strand	4951	0.09
chr1_208382716_208382867	0.37	PLXNA2	plexin A2	34874	0.24
chr3_149954251_149954402	0.37	RP11-167H9.4		138507	0.04
chr17_43205364_43205515	0.37	PLCD3	phospholipase C, delta 3	4452	0.12
chr17_19651678_19651829	0.37	ALDH3A1	aldehyde dehydrogenase 3 family, member A1	7	0.97
chr5_149887543_149887842	0.37	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	18	0.98
chr17_79532915_79533078	0.37	NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	632	0.54
chr1_9951525_9951676	0.37	CTNNBIP1	catenin, beta interacting protein 1	1695	0.29
chr8_19045282_19045433	0.37	PSD3	pleckstrin and Sec7 domain containing 3	103117	0.08
chr11_63750040_63750285	0.37	OTUB1	OTU domain, ubiquitin aldehyde binding 1	3307	0.14
chr4_187606105_187606371	0.37	FAT1	FAT atypical cadherin 1	38771	0.2
chr8_123772200_123772351	0.37	ZHX2	zinc fingers and homeoboxes 2	21358	0.21
chr1_234700121_234700537	0.36	ENSG00000212144	.	28692	0.16
chr1_152022964_152023546	0.36	S100A11	S100 calcium binding protein A11	13744	0.14
chr15_41573424_41573575	0.36	CHP1	calcineurin-like EF-hand protein 1	24391	0.13
chr3_124277818_124277969	0.36	KALRN	kalirin, RhoGEF kinase	25613	0.23
chr11_86447090_86447241	0.36	PRSS23	protease, serine, 23	54936	0.15
chr16_66652366_66652517	0.36	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	13017	0.11
chr11_108908571_108908861	0.36	ENSG00000201243	.	32472	0.23
chr6_22367405_22367556	0.36	PRL	prolactin	69750	0.13
chr5_10478976_10479127	0.36	RP11-1C1.7		432	0.81
chr1_225959781_225959947	0.36	SRP9	signal recognition particle 9kDa	5667	0.16
chr22_27602198_27602349	0.36	ENSG00000200443	.	170423	0.04
chr8_91532720_91532871	0.36	ENSG00000199354	.	9439	0.26
chr1_214731522_214731884	0.36	PTPN14	protein tyrosine phosphatase, non-receptor type 14	7137	0.28
chr17_1690708_1690859	0.36	SMYD4	SET and MYND domain containing 4	13316	0.11
chr2_28497749_28498516	0.36	AC093690.1		35194	0.19
chr3_149469081_149469660	0.36	COMMD2	COMM domain containing 2	916	0.55
chr3_185450728_185450956	0.36	C3orf65	chromosome 3 open reading frame 65	19762	0.2
chr12_77425923_77426193	0.35	E2F7	E2F transcription factor 7	18468	0.27
chr3_123979690_123979841	0.35	KALRN	kalirin, RhoGEF kinase	32928	0.22
chr8_129187891_129188042	0.35	ENSG00000221261	.	25604	0.21
chr15_83611739_83611890	0.35	HOMER2	homer homolog 2 (Drosophila)	9659	0.14
chr1_205114875_205115026	0.35	RBBP5	retinoblastoma binding protein 5	23807	0.16
chr10_91043296_91043536	0.35	RP11-149I23.3		106	0.95
chr5_131600580_131600731	0.35	PDLIM4	PDZ and LIM domain 4	3513	0.2
chr6_149199848_149199999	0.35	RP11-162J8.2		85897	0.09
chr10_79709340_79709491	0.35	DLG5-AS1	DLG5 antisense RNA 1	22285	0.16
chr6_39855140_39855437	0.35	RP11-61I13.3		944	0.63
chr12_110388287_110388838	0.35	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	45467	0.11
chr5_139069097_139069307	0.35	CXXC5	CXXC finger protein 5	9934	0.2
chr5_77902045_77902196	0.35	LHFPL2	lipoma HMGIC fusion partner-like 2	42528	0.21
chr5_180213979_180214228	0.35	CTC-205M6.5		766	0.61
chr16_54025361_54025773	0.35	RP11-357N13.2		8314	0.19
chr12_53465095_53465401	0.35	SPRYD3	SPRY domain containing 3	7913	0.11
chr10_30236708_30236859	0.34	KIAA1462	KIAA1462	111670	0.07
chr15_74629333_74629484	0.34	CCDC33	coiled-coil domain containing 33	18497	0.13
chr6_155703153_155703304	0.34	TFB1M	transcription factor B1, mitochondrial	67610	0.11
chr8_12583298_12583449	0.34	ENSG00000266206	.	1440	0.38
chr13_111411891_111412042	0.34	ING1	inhibitor of growth family, member 1	44637	0.15
chr15_32993894_32994045	0.34	GREM1	gremlin 1, DAN family BMP antagonist	16206	0.17
chr5_82772375_82772526	0.34	VCAN	versican	4706	0.32
chr6_3743005_3743681	0.34	PXDC1	PX domain containing 1	4215	0.25
chr19_17218227_17218378	0.34	MYO9B	myosin IXB	5774	0.13
chr5_111004543_111004694	0.34	ENSG00000253057	.	51140	0.14
chr11_12307449_12307766	0.34	MICALCL	MICAL C-terminal like	840	0.61
chr4_24227998_24228149	0.34	ENSG00000222262	.	194851	0.03
chr1_200341478_200341663	0.34	ZNF281	zinc finger protein 281	37550	0.22
chr9_14251628_14251779	0.34	NFIB	nuclear factor I/B	56309	0.15
chr2_227525621_227525772	0.34	ENSG00000263363	.	2187	0.45
chr5_395973_396219	0.34	AHRR	aryl-hydrocarbon receptor repressor	24939	0.14
chr13_101959109_101959260	0.34	NALCN	sodium leak channel, non-selective	92321	0.09
chr6_14286162_14286313	0.33	ENSG00000238987	.	129544	0.06
chr12_53693833_53694662	0.33	RP11-680A11.5		149	0.73
chr3_53277561_53277865	0.33	TKT	transketolase	12303	0.14
chr2_169371779_169371930	0.33	CERS6	ceramide synthase 6	59095	0.11
chr21_37575111_37575262	0.33	ENSG00000265882	.	10950	0.15
chr18_46148945_46149096	0.33	ENSG00000266276	.	47951	0.15
chr8_101471248_101471399	0.33	KB-1615E4.2		16580	0.18
chr15_40384302_40384677	0.33	RP11-521C20.3		3456	0.2
chr12_52182216_52182367	0.33	AC068987.1	HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881	21498	0.2
chr4_77956814_77956965	0.33	SEPT11	septin 11	7019	0.23
chr11_130652591_130652742	0.33	C11orf44	chromosome 11 open reading frame 44	109815	0.07
chr1_109934550_109935130	0.33	SORT1	sortilin 1	1139	0.45
chr10_79150233_79150384	0.33	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	13434	0.23
chr1_154379358_154380147	0.33	RP11-350G8.5		712	0.52
chr14_69522934_69523085	0.33	ACTN1-AS1	ACTN1 antisense RNA 1	76251	0.09
chr6_113330842_113330993	0.33	ENSG00000201386	.	38222	0.23
chr1_223584357_223584508	0.33	C1orf65	chromosome 1 open reading frame 65	17717	0.2
chr1_150481830_150481981	0.33	ECM1	extracellular matrix protein 1	1322	0.29

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.3	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.2	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	0.2	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.2	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.2	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0045628	regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.2	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.3	GO:0031269	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0	0.2	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.2	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.2	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0051580	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.4	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.3	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.0	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.3	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.3	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0072666	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0	0.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:0072193	ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.3	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0034227	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.7	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0090493	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0060841	venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.0	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.0	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0034405	response to fluid shear stress(GO:0034405)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.0	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.1	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.0	0.1	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.0	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	1.7	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.3	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.3	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.5	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.2	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.3	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0032356	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.4	PID AURORA A PATHWAY	Aurora A signaling
0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.6	NABA COLLAGENS	Genes encoding collagen proteins
0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	PID ATR PATHWAY	ATR signaling pathway
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	PID S1P S1P2 PATHWAY	S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.0	REACTOME IMMUNE SYSTEM	Genes involved in Immune System
0.0	0.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism