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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for GTF2I

Z-value: 1.20

Motif logo

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Transcription factors associated with GTF2I

Gene Symbol Gene ID Gene Info
GTF2I
ENSG00000077809.8 general transcription factor IIi

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_74071229_74071632GTF2I5810.795860-0.801.0e-02Click!
chr7_74081638_74081789GTF2I93560.225626-0.801.0e-02Click!
chr7_74048042_74048193GTF2I238940.190203-0.771.4e-02Click!
chr7_74074150_74074543GTF2I19890.380716-0.742.2e-02Click!
chr7_74057428_74057605GTF2I144950.214789-0.732.7e-02Click!

Activity of the GTF2I motif across conditions

Conditions sorted by the z-value of the GTF2I motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_10417901_10418493 1.33 ENSG00000264030
 .
 2560
 0.25
chr19_7989733_7990535 0.76 CTD-3193O13.8
752
 0.29
chr8_140716343_140716851 0.55 KCNK9
 potassium channel, subfamily K, member 9
 1298
 0.63
chr9_94579747_94580327 0.53 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 131125
 0.05
chr7_2672947_2673687 0.46 TTYH3
 tweety family member 3
 1527
 0.39
chr21_47714776_47715544 0.44 YBEY
 ybeY metallopeptidase (putative)
 8601
 0.11
chr14_103986978_103987655 0.42 CKB
 creatine kinase, brain
 122
 0.92
chr3_13045853_13046441 0.39 IQSEC1
 IQ motif and Sec7 domain 1
 17611
 0.25
chr17_38500621_38501691 0.38 RARA
 retinoic acid receptor, alpha
 337
 0.77
chr13_33682757_33682908 0.36 STARD13-IT1
 STARD13 intronic transcript 1 (non-protein coding)
 55714
 0.13
chr2_42795325_42795726 0.35 MTA3
 metastasis associated 1 family, member 3
 132
 0.97
chr1_156092867_156093791 0.35 LMNA
 lamin A/C
 2622
 0.16
chr2_218723094_218723245 0.32 TNS1
 tensin 1
 16286
 0.25
chr8_49565421_49565933 0.31 EFCAB1
 EF-hand calcium binding domain 1
 76671
 0.11
chr10_134367045_134367383 0.31 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 15571
 0.21
chr10_72647360_72647920 0.31 PCBD1
 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
 901
 0.61
chr12_2494439_2494710 0.30 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 115632
 0.06
chr7_73868587_73869056 0.30 GTF2IRD1
 GTF2I repeat domain containing 1
 382
 0.88
chr11_65343918_65345038 0.30 EHBP1L1
 EH domain binding protein 1-like 1
 961
 0.3
chr12_64237243_64237632 0.30 SRGAP1
 SLIT-ROBO Rho GTPase activating protein 1
 636
 0.66
chr9_130601372_130601801 0.28 ENSG00000222455
 .
 1915
 0.15
chr17_40994290_40994441 0.28 AOC2
 amine oxidase, copper containing 2 (retina-specific)
 2252
 0.13
chr7_128431078_128431544 0.28 CCDC136
 coiled-coil domain containing 136
 153
 0.93
chrX_39865307_39865929 0.27 BCOR
 BCL6 corepressor
 56572
 0.16
chr12_133078846_133079257 0.27 FBRSL1
 fibrosin-like 1
 11894
 0.2
chr20_2839933_2840363 0.27 VPS16
 vacuolar protein sorting 16 homolog (S. cerevisiae)
 2955
 0.18
chr12_106533043_106533555 0.27 NUAK1
 NUAK family, SNF1-like kinase, 1
 512
 0.83
chr1_212405280_212405592 0.27 PPP2R5A
 protein phosphatase 2, regulatory subunit B', alpha
 53443
 0.11
chr3_184287134_184287636 0.26 EPHB3
 EPH receptor B3
 7813
 0.2
chr16_55521708_55521859 0.26 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
 791
 0.69
chr10_104436480_104437015 0.26 TRIM8
 tripartite motif containing 8
 32103
 0.12
chr1_109138261_109138412 0.26 FAM102B
 family with sequence similarity 102, member B
 35625
 0.16
chr15_41786624_41787259 0.26 ITPKA
 inositol-trisphosphate 3-kinase A
 868
 0.5
chr17_45867102_45867637 0.26 OSBPL7
 oxysterol binding protein-like 7
 31767
 0.1
chr7_98029982_98030440 0.26 BAIAP2L1
 BAI1-associated protein 2-like 1
 169
 0.97
chr8_104152774_104152925 0.25 BAALC
 brain and acute leukemia, cytoplasmic
 89
 0.91
chr11_8741654_8741805 0.25 ST5
 suppression of tumorigenicity 5
 1039
 0.41
chrX_134185283_134186016 0.24 FAM127B
 family with sequence similarity 127, member B
 556
 0.74
chr7_1619213_1619508 0.24 PSMG3
 proteasome (prosome, macropain) assembly chaperone 3
 8719
 0.17
chr8_49289133_49289284 0.24 ENSG00000252710
 .
 68618
 0.14
chr11_3159025_3159707 0.23 OSBPL5
 oxysterol binding protein-like 5
 8807
 0.17
chr19_55593378_55593915 0.23 EPS8L1
 EPS8-like 1
 1886
 0.2
chr17_56031434_56032135 0.23 CUEDC1
 CUE domain containing 1
 834
 0.58
chr9_88899289_88899440 0.23 ISCA1
 iron-sulfur cluster assembly 1
 1688
 0.36
chr22_50243343_50244155 0.23 ZBED4
 zinc finger, BED-type containing 4
 3741
 0.22
chr6_56180319_56180615 0.23 RP3-445N2.1
16448
 0.26
chr16_73081442_73081894 0.23 ZFHX3
 zinc finger homeobox 3
 606
 0.78
chr21_46825889_46826320 0.23 COL18A1
 collagen, type XVIII, alpha 1
 1052
 0.46
chr16_75284868_75285315 0.23 BCAR1
 breast cancer anti-estrogen resistance 1
 246
 0.89
chr1_38471719_38472149 0.23 FHL3
 four and a half LIM domains 3
 757
 0.54
chr14_105993130_105993899 0.23 TMEM121
 transmembrane protein 121
 574
 0.65
chr14_24837858_24838637 0.23 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 41
 0.94
chr1_207980505_207981161 0.23 ENSG00000203709
 .
 4965
 0.27
chr12_117463931_117464197 0.22 TESC
 tescalcin
 20572
 0.21
chr6_41513317_41513955 0.22 RP11-328M4.2
176
 0.81
chr16_2518153_2518704 0.22 RP11-715J22.2
214
 0.81
chr8_49341467_49342503 0.22 ENSG00000252710
 .
 121395
 0.06
chr7_5452888_5453131 0.22 TNRC18
 trinucleotide repeat containing 18
 5984
 0.15
chr17_57432844_57432995 0.22 YPEL2
 yippee-like 2 (Drosophila)
 10402
 0.17
chr2_74777231_74777572 0.22 LOXL3
 lysyl oxidase-like 3
 815
 0.34
chr14_61747742_61748391 0.22 TMEM30B
 transmembrane protein 30B
 107
 0.63
chr16_776196_776865 0.22 CCDC78
 coiled-coil domain containing 78
 57
 0.81
chr19_1755732_1755984 0.22 ONECUT3
 one cut homeobox 3
 3486
 0.17
chr3_123509920_123510071 0.21 MYLK
 myosin light chain kinase
 2693
 0.3
chr2_242746190_242746341 0.21 NEU4
 sialidase 4
 3655
 0.12
chr15_41221926_41222903 0.21 DLL4
 delta-like 4 (Drosophila)
 823
 0.5
chr16_28543798_28543949 0.21 NUPR1
 nuclear protein, transcriptional regulator, 1
 6456
 0.13
chr16_744329_744818 0.21 FBXL16
 F-box and leucine-rich repeat protein 16
 1452
 0.14
chr9_131936786_131937499 0.21 RP11-247A12.8
944
 0.4
chr11_1146453_1147024 0.21 MUC5AC
 mucin 5AC, oligomeric mucus/gel-forming
 4842
 0.22
chr11_123008436_123008892 0.21 CTD-2216M2.1
50846
 0.11
chr5_157940975_157941126 0.20 CTD-2363C16.1
468964
 0.01
chr1_45308919_45309214 0.20 PTCH2
 patched 2
 331
 0.79
chr21_46713806_46714461 0.20 ENSG00000215447
 .
 6166
 0.19
chr5_177826208_177826359 0.20 ENSG00000242341
 .
 21358
 0.18
chr11_19791928_19792079 0.20 NAV2
 neuron navigator 2
 7010
 0.24
chr12_6445245_6445959 0.20 TNFRSF1A
 tumor necrosis factor receptor superfamily, member 1A
 5412
 0.13
chr11_125983043_125983210 0.20 CDON
 cell adhesion associated, oncogene regulated
 49896
 0.11
chr11_46312622_46312792 0.20 CREB3L1
 cAMP responsive element binding protein 3-like 1
 3970
 0.21
chr7_75911267_75911842 0.20 SRRM3
 serine/arginine repetitive matrix 3
 378
 0.84
chr6_21596350_21596989 0.20 SOX4
 SRY (sex determining region Y)-box 4
 2598
 0.45
chr13_28534615_28535489 0.20 CDX2
 caudal type homeobox 2
 10224
 0.14
chr19_461630_462007 0.20 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 822
 0.45
chr19_42781870_42782547 0.19 CIC
 capicua transcriptional repressor
 5964
 0.09
chr3_123826537_123826688 0.19 KALRN
 kalirin, RhoGEF kinase
 13054
 0.2
chr18_34834300_34834543 0.19 CELF4
 CUGBP, Elav-like family member 4
 10296
 0.2
chr22_24169181_24169332 0.19 DERL3
 derlin 3
 11935
 0.09
chr16_85784826_85785175 0.19 C16orf74
 chromosome 16 open reading frame 74
 265
 0.86
chr7_100859763_100860679 0.19 ZNHIT1
 zinc finger, HIT-type containing 1
 728
 0.34
chr19_44144210_44144820 0.19 CADM4
 cell adhesion molecule 4
 524
 0.59
chr11_113345070_113345599 0.19 DRD2
 dopamine receptor D2
 508
 0.8
chr19_13133727_13134698 0.19 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 593
 0.58
chr5_71448848_71449179 0.19 ENSG00000264099
 .
 16281
 0.23
chr11_67141426_67142374 0.19 CLCF1
 cardiotrophin-like cytokine factor 1
 252
 0.81
chr5_72485513_72485664 0.19 TMEM174
 transmembrane protein 174
 16566
 0.18
chr22_46525487_46525827 0.19 ENSG00000207875
 .
 16091
 0.1
chr17_40913377_40913932 0.19 RAMP2
 receptor (G protein-coupled) activity modifying protein 2
 378
 0.71
chr1_156675699_156676565 0.19 CRABP2
 cellular retinoic acid binding protein 2
 524
 0.6
chr2_12958377_12958528 0.19 ENSG00000264370
 .
 80959
 0.11
chr5_14398322_14398473 0.19 TRIO
 trio Rho guanine nucleotide exchange factor
 90160
 0.1
chr2_232419389_232419839 0.19 NMUR1
 neuromedin U receptor 1
 24408
 0.13
chr17_73992846_73993556 0.19 CDK3
 cyclin-dependent kinase 3
 3786
 0.12
chr17_38501915_38502668 0.18 RARA
 retinoic acid receptor, alpha
 798
 0.45
chr19_19245450_19245992 0.18 TMEM161A
 transmembrane protein 161A
 2511
 0.19
chr2_235900449_235900600 0.18 SH3BP4
 SH3-domain binding protein 4
 2960
 0.42
chr19_2097349_2098074 0.18 IZUMO4
 IZUMO family member 4
 830
 0.37
chr6_125346782_125347068 0.18 RNF217
 ring finger protein 217
 22433
 0.24
chr19_13206700_13207253 0.18 LYL1
 lymphoblastic leukemia derived sequence 1
 6705
 0.11
chr5_139049687_139050600 0.18 CXXC5
 CXXC finger protein 5
 4878
 0.24
chr5_177965097_177965248 0.18 COL23A1
 collagen, type XXIII, alpha 1
 24067
 0.2
chr17_27459777_27460175 0.18 MYO18A
 myosin XVIIIA
 7460
 0.15
chr11_125985239_125985390 0.18 CDON
 cell adhesion associated, oncogene regulated
 52084
 0.1
chr19_10928760_10928918 0.18 ENSG00000207752
 .
 667
 0.57
chr3_122803125_122803484 0.18 PDIA5
 protein disulfide isomerase family A, member 5
 17109
 0.23
chr1_21561803_21561954 0.18 RP3-329E20.2
30697
 0.15
chr22_38850403_38851076 0.18 KCNJ4
 potassium inwardly-rectifying channel, subfamily J, member 4
 466
 0.74
chr15_67303268_67303419 0.18 SMAD3
 SMAD family member 3
 52758
 0.16
chr19_1324652_1325370 0.18 MUM1
 melanoma associated antigen (mutated) 1
 29699
 0.07
chr2_97197247_97197870 0.18 RP11-363D14.1
485
 0.79
chr4_10105956_10106688 0.18 ENSG00000223086
 .
 11186
 0.15
chr17_1534982_1535133 0.18 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
 2927
 0.14
chr5_179246518_179247261 0.18 SQSTM1
 sequestosome 1
 870
 0.42
chr5_63932962_63933350 0.18 FAM159B
 family with sequence similarity 159, member B
 52979
 0.14
chr19_4115268_4115780 0.18 MAP2K2
 mitogen-activated protein kinase kinase 2
 8590
 0.13
chr19_54727093_54727479 0.18 LILRB3
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
 92
 0.92
chr19_45430034_45430698 0.18 APOC1P1
 apolipoprotein C-I pseudogene 1
 133
 0.9
chr10_119973133_119973284 0.18 FAM204A
 family with sequence similarity 204, member A
 128544
 0.05
chr5_172323723_172324191 0.18 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 8263
 0.19
chr15_90745308_90745813 0.18 SEMA4B
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
 792
 0.52
chr8_21494888_21495039 0.18 ENSG00000266630
 .
 87454
 0.09
chr21_46347768_46348484 0.18 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 507
 0.62
chr7_15498785_15499062 0.18 AGMO
 alkylglycerol monooxygenase
 93076
 0.1
chr1_44883284_44883666 0.17 RNF220
 ring finger protein 220
 5705
 0.21
chrX_17844639_17844790 0.17 RAI2
 retinoic acid induced 2
 11136
 0.29
chr6_85845994_85846180 0.17 NT5E
 5'-nucleotidase, ecto (CD73)
 313722
 0.01
chr22_50741047_50741266 0.17 PLXNB2
 plexin B2
 1265
 0.26
chr22_29469276_29469693 0.17 KREMEN1
 kringle containing transmembrane protein 1
 365
 0.83
chr5_151044309_151044460 0.17 CTB-113P19.1
12122
 0.14
chr19_1361317_1362052 0.17 MUM1
 melanoma associated antigen (mutated) 1
 5321
 0.1
chr21_37923566_37923717 0.17 CLDN14
 claudin 14
 8743
 0.23
chr3_141929744_141929895 0.17 GK5
 glycerol kinase 5 (putative)
 14609
 0.22
chr19_54637471_54637622 0.17 CNOT3
 CCR4-NOT transcription complex, subunit 3
 3898
 0.09
chr12_2560717_2560868 0.17 CACNA1C-AS3
 CACNA1C antisense RNA 3
 155814
 0.04
chr10_64379208_64379359 0.17 ZNF365
 zinc finger protein 365
 24250
 0.22
chr13_94725792_94725943 0.17 ENSG00000212559
 .
 48015
 0.19
chr3_72442498_72442652 0.17 RYBP
 RING1 and YY1 binding protein
 53494
 0.16
chr17_10128061_10128212 0.17 GAS7
 growth arrest-specific 7
 26268
 0.18
chr1_54685877_54686028 0.17 MRPL37
 mitochondrial ribosomal protein L37
 10333
 0.13
chr15_66209053_66209318 0.17 RAB11A
 RAB11A, member RAS oncogene family
 46834
 0.13
chr4_3709772_3710024 0.17 ADRA2C
 adrenoceptor alpha 2C
 58177
 0.14
chr4_7904697_7904890 0.17 AFAP1
 actin filament associated protein 1
 30753
 0.17
chr8_118994127_118994278 0.17 EXT1
 exostosin glycosyltransferase 1
 128451
 0.06
chr2_197189762_197189913 0.17 ENSG00000264627
 .
 35704
 0.16
chr1_211503644_211504001 0.17 TRAF5
 TNF receptor-associated factor 5
 3643
 0.3
chr19_13213848_13214497 0.17 LYL1
 lymphoblastic leukemia derived sequence 1
 197
 0.89
chr13_114885176_114885502 0.17 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 11044
 0.21
chr5_139104544_139104695 0.17 ENSG00000200756
 .
 6944
 0.22
chr17_40833679_40833973 0.16 CCR10
 chemokine (C-C motif) receptor 10
 35
 0.91
chr3_170340455_170340606 0.16 RP11-373E16.3
33821
 0.18
chr1_110922648_110923109 0.16 SLC16A4
 solute carrier family 16, member 4
 1073
 0.36
chr5_72659852_72660019 0.16 FOXD1
 forkhead box D1
 84417
 0.08
chr19_34311473_34312146 0.16 KCTD15
 potassium channel tetramerization domain containing 15
 13980
 0.27
chr2_158177617_158177768 0.16 ERMN
 ermin, ERM-like protein
 4058
 0.26
chr17_19993225_19993666 0.16 SPECC1
 sperm antigen with calponin homology and coiled-coil domains 1
 3110
 0.28
chr9_130615331_130616090 0.16 ENG
 endoglin
 1205
 0.25
chr9_129961402_129961553 0.16 RALGPS1
 Ral GEF with PH domain and SH3 binding motif 1
 11547
 0.18
chr5_5350867_5351018 0.16 KIAA0947
 KIAA0947
 71865
 0.13
chr11_33721547_33721982 0.16 C11orf91
 chromosome 11 open reading frame 91
 179
 0.94
chr17_76875045_76875748 0.16 TIMP2
 TIMP metallopeptidase inhibitor 2
 5164
 0.16
chr11_72470083_72470393 0.16 STARD10
 StAR-related lipid transfer (START) domain containing 10
 116
 0.94
chr4_10105412_10105563 0.16 ENSG00000223086
 .
 12021
 0.15
chr5_38424510_38424661 0.16 EGFLAM-AS1
 EGFLAM antisense RNA 1
 2893
 0.23
chr6_24901597_24902091 0.16 FAM65B
 family with sequence similarity 65, member B
 9351
 0.22
chr19_16448880_16449487 0.16 KLF2
 Kruppel-like factor 2
 13532
 0.14
chr11_73039124_73039275 0.16 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 16589
 0.12
chr3_129311849_129312381 0.16 ENSG00000239437
 .
 1923
 0.28
chr1_156096167_156097087 0.16 LMNA
 lamin A/C
 33
 0.96
chr17_40492798_40492949 0.16 STAT5A
 signal transducer and activator of transcription 5A
 34685
 0.09
chr7_492646_493023 0.16 PDGFA
 platelet-derived growth factor alpha polypeptide
 65311
 0.11
chr16_4378324_4378965 0.16 GLIS2
 GLIS family zinc finger 2
 3581
 0.16
chr17_66348034_66348185 0.16 ARSG
 arylsulfatase G
 60450
 0.09
chr13_24205823_24205974 0.16 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 52379
 0.16
chr20_50028653_50029381 0.16 ENSG00000263645
 .
 35159
 0.18
chr17_38128356_38128623 0.16 GSDMA
 gasdermin A
 6713
 0.12
chr5_31854978_31855350 0.16 ENSG00000251887
 .
 22618
 0.13
chr1_22745301_22745452 0.16 ZBTB40
 zinc finger and BTB domain containing 40
 32968
 0.19
chr4_1237782_1238175 0.16 CTBP1
 C-terminal binding protein 1
 2267
 0.22
chr8_93031342_93031493 0.16 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 14
 0.99
chr12_12016346_12017014 0.16 ETV6
 ets variant 6
 22191
 0.26
chr2_47201847_47202176 0.16 RP11-15I20.1
17984
 0.15
chr15_74906801_74907591 0.16 CLK3
 CDC-like kinase 3
 26
 0.93
chr3_87003421_87003572 0.16 VGLL3
 vestigial like 3 (Drosophila)
 36356
 0.24
chr12_63161016_63161167 0.16 ENSG00000200296
 .
 83590
 0.09
chr8_144922026_144922763 0.16 NRBP2
 nuclear receptor binding protein 2
 408
 0.7
chr5_175299080_175299718 0.16 CPLX2
 complexin 2
 414
 0.87
chr10_3493784_3493935 0.16 PITRM1
 pitrilysin metallopeptidase 1
 278856
 0.01
chr3_45127227_45127378 0.16 ENSG00000252410
 .
 51222
 0.11
chr17_36862672_36863533 0.15 CTB-58E17.3
588
 0.44
chr18_32656273_32656556 0.15 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 34800
 0.22
chr11_43701160_43701492 0.15 HSD17B12
 hydroxysteroid (17-beta) dehydrogenase 12
 933
 0.68

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1 0.4 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.2 GO:0032261 purine nucleotide salvage(GO:0032261)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0051892 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.5 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.0 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0071675 positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:2000649 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.0 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0006168 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.0 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:2000258 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.0 GO:0043205 fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis