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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GTF2I

Z-value: 1.20

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Transcription factors associated with GTF2I

Gene Symbol	Gene ID	Gene Info
GTF2I Ensembl NCBI GeneCards UniProt	ENSG00000077809.8	GTF2I

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GTF2I	chr7_74071229_74071632	581	0.795860	-0.80	1.0e-02	Click!
GTF2I	chr7_74081638_74081789	9356	0.225626	-0.80	1.0e-02	Click!
GTF2I	chr7_74048042_74048193	23894	0.190203	-0.77	1.4e-02	Click!
GTF2I	chr7_74074150_74074543	1989	0.380716	-0.74	2.2e-02	Click!
GTF2I	chr7_74057428_74057605	14495	0.214789	-0.73	2.7e-02	Click!

Activity of the GTF2I motif across conditions

Conditions sorted by the z-value of the GTF2I motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_10417901_10418493	1.33	ENSG00000264030	.	2560	0.25
chr19_7989733_7990535	0.76	CTD-3193O13.8		752	0.29
chr8_140716343_140716851	0.55	KCNK9	potassium channel, subfamily K, member 9	1298	0.63
chr9_94579747_94580327	0.53	ROR2	receptor tyrosine kinase-like orphan receptor 2	131125	0.05
chr7_2672947_2673687	0.46	TTYH3	tweety family member 3	1527	0.39
chr21_47714776_47715544	0.44	YBEY	ybeY metallopeptidase (putative)	8601	0.11
chr14_103986978_103987655	0.42	CKB	creatine kinase, brain	122	0.92
chr3_13045853_13046441	0.39	IQSEC1	IQ motif and Sec7 domain 1	17611	0.25
chr17_38500621_38501691	0.38	RARA	retinoic acid receptor, alpha	337	0.77
chr13_33682757_33682908	0.36	STARD13-IT1	STARD13 intronic transcript 1 (non-protein coding)	55714	0.13
chr2_42795325_42795726	0.35	MTA3	metastasis associated 1 family, member 3	132	0.97
chr1_156092867_156093791	0.35	LMNA	lamin A/C	2622	0.16
chr2_218723094_218723245	0.32	TNS1	tensin 1	16286	0.25
chr8_49565421_49565933	0.31	EFCAB1	EF-hand calcium binding domain 1	76671	0.11
chr10_134367045_134367383	0.31	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	15571	0.21
chr10_72647360_72647920	0.31	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	901	0.61
chr12_2494439_2494710	0.30	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	115632	0.06
chr7_73868587_73869056	0.30	GTF2IRD1	GTF2I repeat domain containing 1	382	0.88
chr11_65343918_65345038	0.30	EHBP1L1	EH domain binding protein 1-like 1	961	0.3
chr12_64237243_64237632	0.30	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	636	0.66
chr9_130601372_130601801	0.28	ENSG00000222455	.	1915	0.15
chr17_40994290_40994441	0.28	AOC2	amine oxidase, copper containing 2 (retina-specific)	2252	0.13
chr7_128431078_128431544	0.28	CCDC136	coiled-coil domain containing 136	153	0.93
chrX_39865307_39865929	0.27	BCOR	BCL6 corepressor	56572	0.16
chr12_133078846_133079257	0.27	FBRSL1	fibrosin-like 1	11894	0.2
chr20_2839933_2840363	0.27	VPS16	vacuolar protein sorting 16 homolog (S. cerevisiae)	2955	0.18
chr12_106533043_106533555	0.27	NUAK1	NUAK family, SNF1-like kinase, 1	512	0.83
chr1_212405280_212405592	0.27	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	53443	0.11
chr3_184287134_184287636	0.26	EPHB3	EPH receptor B3	7813	0.2
chr16_55521708_55521859	0.26	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	791	0.69
chr10_104436480_104437015	0.26	TRIM8	tripartite motif containing 8	32103	0.12
chr1_109138261_109138412	0.26	FAM102B	family with sequence similarity 102, member B	35625	0.16
chr15_41786624_41787259	0.26	ITPKA	inositol-trisphosphate 3-kinase A	868	0.5
chr17_45867102_45867637	0.26	OSBPL7	oxysterol binding protein-like 7	31767	0.1
chr7_98029982_98030440	0.26	BAIAP2L1	BAI1-associated protein 2-like 1	169	0.97
chr8_104152774_104152925	0.25	BAALC	brain and acute leukemia, cytoplasmic	89	0.91
chr11_8741654_8741805	0.25	ST5	suppression of tumorigenicity 5	1039	0.41
chrX_134185283_134186016	0.24	FAM127B	family with sequence similarity 127, member B	556	0.74
chr7_1619213_1619508	0.24	PSMG3	proteasome (prosome, macropain) assembly chaperone 3	8719	0.17
chr8_49289133_49289284	0.24	ENSG00000252710	.	68618	0.14
chr11_3159025_3159707	0.23	OSBPL5	oxysterol binding protein-like 5	8807	0.17
chr19_55593378_55593915	0.23	EPS8L1	EPS8-like 1	1886	0.2
chr17_56031434_56032135	0.23	CUEDC1	CUE domain containing 1	834	0.58
chr9_88899289_88899440	0.23	ISCA1	iron-sulfur cluster assembly 1	1688	0.36
chr22_50243343_50244155	0.23	ZBED4	zinc finger, BED-type containing 4	3741	0.22
chr6_56180319_56180615	0.23	RP3-445N2.1		16448	0.26
chr16_73081442_73081894	0.23	ZFHX3	zinc finger homeobox 3	606	0.78
chr21_46825889_46826320	0.23	COL18A1	collagen, type XVIII, alpha 1	1052	0.46
chr16_75284868_75285315	0.23	BCAR1	breast cancer anti-estrogen resistance 1	246	0.89
chr1_38471719_38472149	0.23	FHL3	four and a half LIM domains 3	757	0.54
chr14_105993130_105993899	0.23	TMEM121	transmembrane protein 121	574	0.65
chr14_24837858_24838637	0.23	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	41	0.94
chr1_207980505_207981161	0.23	ENSG00000203709	.	4965	0.27
chr12_117463931_117464197	0.22	TESC	tescalcin	20572	0.21
chr6_41513317_41513955	0.22	RP11-328M4.2		176	0.81
chr16_2518153_2518704	0.22	RP11-715J22.2		214	0.81
chr8_49341467_49342503	0.22	ENSG00000252710	.	121395	0.06
chr7_5452888_5453131	0.22	TNRC18	trinucleotide repeat containing 18	5984	0.15
chr17_57432844_57432995	0.22	YPEL2	yippee-like 2 (Drosophila)	10402	0.17
chr2_74777231_74777572	0.22	LOXL3	lysyl oxidase-like 3	815	0.34
chr14_61747742_61748391	0.22	TMEM30B	transmembrane protein 30B	107	0.63
chr16_776196_776865	0.22	CCDC78	coiled-coil domain containing 78	57	0.81
chr19_1755732_1755984	0.22	ONECUT3	one cut homeobox 3	3486	0.17
chr3_123509920_123510071	0.21	MYLK	myosin light chain kinase	2693	0.3
chr2_242746190_242746341	0.21	NEU4	sialidase 4	3655	0.12
chr15_41221926_41222903	0.21	DLL4	delta-like 4 (Drosophila)	823	0.5
chr16_28543798_28543949	0.21	NUPR1	nuclear protein, transcriptional regulator, 1	6456	0.13
chr16_744329_744818	0.21	FBXL16	F-box and leucine-rich repeat protein 16	1452	0.14
chr9_131936786_131937499	0.21	RP11-247A12.8		944	0.4
chr11_1146453_1147024	0.21	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	4842	0.22
chr11_123008436_123008892	0.21	CTD-2216M2.1		50846	0.11
chr5_157940975_157941126	0.20	CTD-2363C16.1		468964	0.01
chr1_45308919_45309214	0.20	PTCH2	patched 2	331	0.79
chr21_46713806_46714461	0.20	ENSG00000215447	.	6166	0.19
chr5_177826208_177826359	0.20	ENSG00000242341	.	21358	0.18
chr11_19791928_19792079	0.20	NAV2	neuron navigator 2	7010	0.24
chr12_6445245_6445959	0.20	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	5412	0.13
chr11_125983043_125983210	0.20	CDON	cell adhesion associated, oncogene regulated	49896	0.11
chr11_46312622_46312792	0.20	CREB3L1	cAMP responsive element binding protein 3-like 1	3970	0.21
chr7_75911267_75911842	0.20	SRRM3	serine/arginine repetitive matrix 3	378	0.84
chr6_21596350_21596989	0.20	SOX4	SRY (sex determining region Y)-box 4	2598	0.45
chr13_28534615_28535489	0.20	CDX2	caudal type homeobox 2	10224	0.14
chr19_461630_462007	0.20	SHC2	SHC (Src homology 2 domain containing) transforming protein 2	822	0.45
chr19_42781870_42782547	0.19	CIC	capicua transcriptional repressor	5964	0.09
chr3_123826537_123826688	0.19	KALRN	kalirin, RhoGEF kinase	13054	0.2
chr18_34834300_34834543	0.19	CELF4	CUGBP, Elav-like family member 4	10296	0.2
chr22_24169181_24169332	0.19	DERL3	derlin 3	11935	0.09
chr16_85784826_85785175	0.19	C16orf74	chromosome 16 open reading frame 74	265	0.86
chr7_100859763_100860679	0.19	ZNHIT1	zinc finger, HIT-type containing 1	728	0.34
chr19_44144210_44144820	0.19	CADM4	cell adhesion molecule 4	524	0.59
chr11_113345070_113345599	0.19	DRD2	dopamine receptor D2	508	0.8
chr19_13133727_13134698	0.19	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	593	0.58
chr5_71448848_71449179	0.19	ENSG00000264099	.	16281	0.23
chr11_67141426_67142374	0.19	CLCF1	cardiotrophin-like cytokine factor 1	252	0.81
chr5_72485513_72485664	0.19	TMEM174	transmembrane protein 174	16566	0.18
chr22_46525487_46525827	0.19	ENSG00000207875	.	16091	0.1
chr17_40913377_40913932	0.19	RAMP2	receptor (G protein-coupled) activity modifying protein 2	378	0.71
chr1_156675699_156676565	0.19	CRABP2	cellular retinoic acid binding protein 2	524	0.6
chr2_12958377_12958528	0.19	ENSG00000264370	.	80959	0.11
chr5_14398322_14398473	0.19	TRIO	trio Rho guanine nucleotide exchange factor	90160	0.1
chr2_232419389_232419839	0.19	NMUR1	neuromedin U receptor 1	24408	0.13
chr17_73992846_73993556	0.19	CDK3	cyclin-dependent kinase 3	3786	0.12
chr17_38501915_38502668	0.18	RARA	retinoic acid receptor, alpha	798	0.45
chr19_19245450_19245992	0.18	TMEM161A	transmembrane protein 161A	2511	0.19
chr2_235900449_235900600	0.18	SH3BP4	SH3-domain binding protein 4	2960	0.42
chr19_2097349_2098074	0.18	IZUMO4	IZUMO family member 4	830	0.37
chr6_125346782_125347068	0.18	RNF217	ring finger protein 217	22433	0.24
chr19_13206700_13207253	0.18	LYL1	lymphoblastic leukemia derived sequence 1	6705	0.11
chr5_139049687_139050600	0.18	CXXC5	CXXC finger protein 5	4878	0.24
chr5_177965097_177965248	0.18	COL23A1	collagen, type XXIII, alpha 1	24067	0.2
chr17_27459777_27460175	0.18	MYO18A	myosin XVIIIA	7460	0.15
chr11_125985239_125985390	0.18	CDON	cell adhesion associated, oncogene regulated	52084	0.1
chr19_10928760_10928918	0.18	ENSG00000207752	.	667	0.57
chr3_122803125_122803484	0.18	PDIA5	protein disulfide isomerase family A, member 5	17109	0.23
chr1_21561803_21561954	0.18	RP3-329E20.2		30697	0.15
chr22_38850403_38851076	0.18	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	466	0.74
chr15_67303268_67303419	0.18	SMAD3	SMAD family member 3	52758	0.16
chr19_1324652_1325370	0.18	MUM1	melanoma associated antigen (mutated) 1	29699	0.07
chr2_97197247_97197870	0.18	RP11-363D14.1		485	0.79
chr4_10105956_10106688	0.18	ENSG00000223086	.	11186	0.15
chr17_1534982_1535133	0.18	SLC43A2	solute carrier family 43 (amino acid system L transporter), member 2	2927	0.14
chr5_179246518_179247261	0.18	SQSTM1	sequestosome 1	870	0.42
chr5_63932962_63933350	0.18	FAM159B	family with sequence similarity 159, member B	52979	0.14
chr19_4115268_4115780	0.18	MAP2K2	mitogen-activated protein kinase kinase 2	8590	0.13
chr19_54727093_54727479	0.18	LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	92	0.92
chr19_45430034_45430698	0.18	APOC1P1	apolipoprotein C-I pseudogene 1	133	0.9
chr10_119973133_119973284	0.18	FAM204A	family with sequence similarity 204, member A	128544	0.05
chr5_172323723_172324191	0.18	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	8263	0.19
chr15_90745308_90745813	0.18	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	792	0.52
chr8_21494888_21495039	0.18	ENSG00000266630	.	87454	0.09
chr21_46347768_46348484	0.18	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	507	0.62
chr7_15498785_15499062	0.18	AGMO	alkylglycerol monooxygenase	93076	0.1
chr1_44883284_44883666	0.17	RNF220	ring finger protein 220	5705	0.21
chrX_17844639_17844790	0.17	RAI2	retinoic acid induced 2	11136	0.29
chr6_85845994_85846180	0.17	NT5E	5'-nucleotidase, ecto (CD73)	313722	0.01
chr22_50741047_50741266	0.17	PLXNB2	plexin B2	1265	0.26
chr22_29469276_29469693	0.17	KREMEN1	kringle containing transmembrane protein 1	365	0.83
chr5_151044309_151044460	0.17	CTB-113P19.1		12122	0.14
chr19_1361317_1362052	0.17	MUM1	melanoma associated antigen (mutated) 1	5321	0.1
chr21_37923566_37923717	0.17	CLDN14	claudin 14	8743	0.23
chr3_141929744_141929895	0.17	GK5	glycerol kinase 5 (putative)	14609	0.22
chr19_54637471_54637622	0.17	CNOT3	CCR4-NOT transcription complex, subunit 3	3898	0.09
chr12_2560717_2560868	0.17	CACNA1C-AS3	CACNA1C antisense RNA 3	155814	0.04
chr10_64379208_64379359	0.17	ZNF365	zinc finger protein 365	24250	0.22
chr13_94725792_94725943	0.17	ENSG00000212559	.	48015	0.19
chr3_72442498_72442652	0.17	RYBP	RING1 and YY1 binding protein	53494	0.16
chr17_10128061_10128212	0.17	GAS7	growth arrest-specific 7	26268	0.18
chr1_54685877_54686028	0.17	MRPL37	mitochondrial ribosomal protein L37	10333	0.13
chr15_66209053_66209318	0.17	RAB11A	RAB11A, member RAS oncogene family	46834	0.13
chr4_3709772_3710024	0.17	ADRA2C	adrenoceptor alpha 2C	58177	0.14
chr4_7904697_7904890	0.17	AFAP1	actin filament associated protein 1	30753	0.17
chr8_118994127_118994278	0.17	EXT1	exostosin glycosyltransferase 1	128451	0.06
chr2_197189762_197189913	0.17	ENSG00000264627	.	35704	0.16
chr1_211503644_211504001	0.17	TRAF5	TNF receptor-associated factor 5	3643	0.3
chr19_13213848_13214497	0.17	LYL1	lymphoblastic leukemia derived sequence 1	197	0.89
chr13_114885176_114885502	0.17	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	11044	0.21
chr5_139104544_139104695	0.17	ENSG00000200756	.	6944	0.22
chr17_40833679_40833973	0.16	CCR10	chemokine (C-C motif) receptor 10	35	0.91
chr3_170340455_170340606	0.16	RP11-373E16.3		33821	0.18
chr1_110922648_110923109	0.16	SLC16A4	solute carrier family 16, member 4	1073	0.36
chr5_72659852_72660019	0.16	FOXD1	forkhead box D1	84417	0.08
chr19_34311473_34312146	0.16	KCTD15	potassium channel tetramerization domain containing 15	13980	0.27
chr2_158177617_158177768	0.16	ERMN	ermin, ERM-like protein	4058	0.26
chr17_19993225_19993666	0.16	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	3110	0.28
chr9_130615331_130616090	0.16	ENG	endoglin	1205	0.25
chr9_129961402_129961553	0.16	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1	11547	0.18
chr5_5350867_5351018	0.16	KIAA0947	KIAA0947	71865	0.13
chr11_33721547_33721982	0.16	C11orf91	chromosome 11 open reading frame 91	179	0.94
chr17_76875045_76875748	0.16	TIMP2	TIMP metallopeptidase inhibitor 2	5164	0.16
chr11_72470083_72470393	0.16	STARD10	StAR-related lipid transfer (START) domain containing 10	116	0.94
chr4_10105412_10105563	0.16	ENSG00000223086	.	12021	0.15
chr5_38424510_38424661	0.16	EGFLAM-AS1	EGFLAM antisense RNA 1	2893	0.23
chr6_24901597_24902091	0.16	FAM65B	family with sequence similarity 65, member B	9351	0.22
chr19_16448880_16449487	0.16	KLF2	Kruppel-like factor 2	13532	0.14
chr11_73039124_73039275	0.16	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	16589	0.12
chr3_129311849_129312381	0.16	ENSG00000239437	.	1923	0.28
chr1_156096167_156097087	0.16	LMNA	lamin A/C	33	0.96
chr17_40492798_40492949	0.16	STAT5A	signal transducer and activator of transcription 5A	34685	0.09
chr7_492646_493023	0.16	PDGFA	platelet-derived growth factor alpha polypeptide	65311	0.11
chr16_4378324_4378965	0.16	GLIS2	GLIS family zinc finger 2	3581	0.16
chr17_66348034_66348185	0.16	ARSG	arylsulfatase G	60450	0.09
chr13_24205823_24205974	0.16	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	52379	0.16
chr20_50028653_50029381	0.16	ENSG00000263645	.	35159	0.18
chr17_38128356_38128623	0.16	GSDMA	gasdermin A	6713	0.12
chr5_31854978_31855350	0.16	ENSG00000251887	.	22618	0.13
chr1_22745301_22745452	0.16	ZBTB40	zinc finger and BTB domain containing 40	32968	0.19
chr4_1237782_1238175	0.16	CTBP1	C-terminal binding protein 1	2267	0.22
chr8_93031342_93031493	0.16	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	14	0.99
chr12_12016346_12017014	0.16	ETV6	ets variant 6	22191	0.26
chr2_47201847_47202176	0.16	RP11-15I20.1		17984	0.15
chr15_74906801_74907591	0.16	CLK3	CDC-like kinase 3	26	0.93
chr3_87003421_87003572	0.16	VGLL3	vestigial like 3 (Drosophila)	36356	0.24
chr12_63161016_63161167	0.16	ENSG00000200296	.	83590	0.09
chr8_144922026_144922763	0.16	NRBP2	nuclear receptor binding protein 2	408	0.7
chr5_175299080_175299718	0.16	CPLX2	complexin 2	414	0.87
chr10_3493784_3493935	0.16	PITRM1	pitrilysin metallopeptidase 1	278856	0.01
chr3_45127227_45127378	0.16	ENSG00000252410	.	51222	0.11
chr17_36862672_36863533	0.15	CTB-58E17.3		588	0.44
chr18_32656273_32656556	0.15	MAPRE2	microtubule-associated protein, RP/EB family, member 2	34800	0.22
chr11_43701160_43701492	0.15	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	933	0.68

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.4	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0032261	purine nucleotide salvage(GO:0032261)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0051892	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0	0.1	GO:0021508	floor plate formation(GO:0021508)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0022009	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0060492	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.5	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.0	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.0	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0090281	negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.1	GO:0071675	positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:2000649	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:1903670	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.0	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0005638	lamin filament(GO:0005638)
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	GO:0033268	node of Ranvier(GO:0033268)
0.1	GO:0071437	invadopodium(GO:0071437)
0.1	GO:0030056	hemidesmosome(GO:0030056)
0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	GO:0001527	microfibril(GO:0001527)
0.0	GO:0048179	activin receptor complex(GO:0048179)
0.1	GO:0031512	motile primary cilium(GO:0031512)
0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	GO:0070852	cell body fiber(GO:0070852)
0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.1	GO:0043256	laminin complex(GO:0043256)
0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	GO:0043205	fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.2	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.0	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis